LOCUS       gnlProkkaDAGPJMLO_31   18450 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DAGPJMLO_31.
ACCESSION   gnlProkkaDAGPJMLO_31
VERSION     gnlProkkaDAGPJMLO_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:05:18
            Original ID  :: gnl|Prokka|DAGPJMLO_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 25525
            Orig. end    :: 43975
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18450
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10405]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..18450
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18450
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(1481..2074)
                     /locus_tag="ctg31_33"
                     /transl_table=11
                     /translation="MKHSRSKNAVLLMIIFICSICLNNVWARETGTMDQLEKENPDDVD
                     KMNKVLYYYNTLFFENYTEEELKQQEKFQKSIHLLNELYFEYGSLENIPILPFDPENIR
                     EGDSLFTEVVAVINTENNETYFVTENDDMKLLKKCLEKLQYYNGNSVTKSNEELTEAIK
                     NFQKEEGLTIDGIAGNEVWRKIDILMLNKVIEDD"
     CDS             complement(2484..4733)
                     /locus_tag="ctg31_34"
                     /transl_table=11
                     /translation="MEKYIIMKKVNKFKLLAAGLLIGVAFWLLGSDFFTFMIWWEILWI
                     LGLVFMPITAQIFKGFDDNGWMYSKVIAIVICGYGVWILTSIKVVHFTTLSSIVITTLC
                     GGSSIAYGIYGKQRKVFLWKHMELVYWEEVIFFVVFLLWTYMAGFHPAAHGTEKYMDFG
                     FMKSMMRSTTLPSEDMWYAGKAFNYYYGGQYFAVFLTKLTGTKVEITYNLMRTMIAAFA
                     FVLPFSLVRQMLKDKLGKRGRAWITDFGGILAGLSVSMSGNLHYIIYGKIFTLLGIRED
                     YWFPSTTRFIGFDPPVTGDETIHEFPSYSFVLGDLHAHVINVFFVLAVLGILYAWIKRN
                     SGKSWKQKEIFLLGLFLGIFLFSNTWDFMIYYVVICGTLFFGNLKRYLNSTDIKPSDMR
                     TGIKWSVVQWIELLLTAVLISLPFHLQFKSVMVQGIGIVKIHTAFYQFCVLWAFPLLIC
                     GLFVVSTLIKNRNFTNKKNRNLFYKINVSDLYGVVLSLCAMGLILIPEIIYVRDIYEKT
                     APRANTMFKLTYQAYILFALMMSYILVFFVADRIKILQETKLDNRYEKKVRLSKVQITV
                     GGMAIILLISTCGYFINATTNWFTGFPLKNKYQTLNATAYLENAIPEDAAAIRWLNKNI
                     TGQPTVLEACGDSYKDYDNRVSAMTGLPTVLGWYVHEWLWRNNLDEENKRRTDVETIYT
                     STDKKEVQELLDKYEVNYIFIGSCEYQKYEGVNVALLSSLGEIVFKKENTMIVKL"
     CDS             complement(5022..6263)
                     /locus_tag="ctg31_35"
                     /transl_table=11
                     /translation="MFALITTLSTNLLRTYIIYRFMRLFFWTDIEEKKKERACYVLFFV
                     LTAVVHLIFCSPGMSVITNIVLIFLITVCYEGALKKKIFVTLLVYGTNMGCDLVAVHLL
                     TDYSITGKVGECAAYITVLLLLICDVISEKILIKNKGEDKTPHGMILAVISALCLAELL
                     IVEQELKNRILLVLFGCCVLAVVLLIFYLYDVLISAYKKLEEQSLMEKQMLIYSHQLDV
                     LMQSEEKVKALRHDLKNHLGELALMAGNQNNEEIWKYIQDMGEYMQNQSELVSCGNKNL
                     DSLLNYLLGQAKKKLNHVEYEVRVPSDLCISAFDLNVILGNLTENAIEAAEQTKDKWMS
                     VDIYYEKGMLSMEIKNSFQHELAVEKNKLLSTKEEKGHGIGLANVRKMVEKYQGFMDVS
                     NTNQIFTVKVMLYL"
     CDS             complement(6264..6557)
                     /locus_tag="ctg31_36"
                     /transl_table=11
                     /translation="MNDRIWSVFFAFSILFVSIFLLDFKVVEFNGKLKEIAKKIPGNFI
                     QIHQSYLINFDYIEECSYESVKMKNGDTIPISQPYRKSVRKQLAERVWRDRE"
     CDS             6570..7265
                     /locus_tag="ctg31_37"
                     /transl_table=11
                     /translation="MDGDGIPLAFSTFAENVNEQTSLKPLEKKILGEFGCQKFIYCSDA
                     DLGSESIREYNHMGERAYIVTQSIKKLKKEEKEWALDPQGFKKVSDDTPVDITKLNSND
                     KGLYYKDEPYTTKKLHQRLIITYSPKYAAYQRTIRDKQVERAQKMLDSGNTKKNRKNPN
                     DPARFIEKTAVTPEGEAADIKYSLDENKITEETLYDGLYAVCTDLLDDNVANILKVSEG
                     RWQIEESRL"
     CDS             complement(7465..8196)
                     /locus_tag="ctg31_38"
                     /transl_table=11
                     /translation="MGERTYIVTTFIKKLKKGEKEWVLSPQGFKRVSDDKTVDISKLPE
                     DDKGLYYKDEPYTTKKLQQRLIITYSPKYALYQKSIRSKQIERAQAMLDSGNTKKNRRN
                     PNNSARFIGTAAVTKESETADIRHYLNEHKISEESQYDGLYAVCTNLSDDEVSDILKVS
                     EGRWQIEECFRIMKTDFSARPVYLRDEKRIKAHFLICFLALMIYRFFGRKLNYKYTCEE
                     SLDTLKAMNFAEIQEQGFIPL"
     CDS             complement(8569..9642)
                     /locus_tag="ctg31_39"
                     /transl_table=11
                     /translation="MVKKLFFVMLTGMICFSSCFCETAFAKTSKVRVYDAEKGTTSFTS
                     FTYSDNKKDESLAPSEGTGAISSASQKAVIFHQADGSTTTRKADSNGKVTLPAIKNETG
                     YTFLGWSTKPDQTQNPQYQAGQVIQVRKKTHLYAVMYNWQQEPDIQVNNLAAQLSEYSG
                     IIFVGDSRTYFMQKTLLQEYGKDAVAKVSFVCKTGEGLSWFETAGERVMRSEIARLQSD
                     SDKPVAVIFNLGVNDLSSHNSGNGVDYKGEANAYLARMNTLAEELESDCRLFYMSVNPV
                     NTAMKPTRKEAQLRYFNDRLQSRLNKRFQWIDTYKYLMKNGYSTYNEFKGNIDDGVHYS
                     TRTYKRIYKYCMNAIRK"
     CDS             complement(9849..9989)
                     /locus_tag="ctg31_40"
                     /transl_table=11
                     /translation="MYVLCIFLNFTAIRSIAITVGVTNLTVGGCVIVGKIKNFVLNSLQ
                     I"
     CDS             complement(10001..10405)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_41"
                     /sec_met_domain="AgrB (E-value: 2.4e-34, bitscore: 109.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METQTFSKEEKEEIIRYGLDRIKSICTMTFVTLLMGCIFQVFFQS
                     IIFLVCFIALRKYAGGYHADTQNRCYVISTAIIAVALLAIRYMSDGSDNEIFILLQSLN
                     FILLYFLVPVDNKNHRLEYWEKEKYGKKQE"
     CDS             complement(10791..12032)
                     /locus_tag="ctg31_42"
                     /transl_table=11
                     /translation="MFALITTLSTNLLRTYIIYRFMRLFFWTDIEEKKKERACYVLFFV
                     LTAVVHLIFCSPGMSVITNIVLIFLITVCYEGALKKKIFVTLLVYGTNMGCDLVAVHLL
                     TDYSITGKVGECAAYITVLLLLICDVISEKILIKNKGEDKTPHGMILAVISALCLAELL
                     IVEQELKNRILLVLFGCCVLAVVLLIFYLYDVLISAYKKLEEQSLMEKQMLIYSHQLDV
                     LMQSEEKVKALRHDLKNHLGELALMAGNQNNEEIWKYIQDMGEYMQNQSELVSCGNKNL
                     DSLLNYLLGQAKKKLNHVEYEVRVPSDLCISAFDLNVILGNLTENAIEAAEQTKDKWMS
                     VDIYYEKGMLSMEIKNSFQHELAVEKNKLLSTKEEKGHGIGLANVRKMVEKYQGFMDVS
                     NTNQIFTVKVMLYL"
     CDS             complement(12033..12755)
                     /locus_tag="ctg31_43"
                     /transl_table=11
                     /translation="MFCIGICDDDEGLCGELEKMLYDYGKEHKIQMNIDIWYQGESLCR
                     FLRENKKILDVLFLDIELLTTNGIEVGRFIREEQENMETAIVYISANSSYAMDLFRVQP
                     TDFLIKPLDKIKVGNVMNRIQKISEVRKGIFEYFGSGYYFKVLYKDILYFSSQNKKVHL
                     VLKDGQKEFNGKLKEIAKKIPGNFIQIHQSYLINFDYIEECSYESVKMKNGDTIPISQP
                     YRKSVRKQLAERVWRDRE"
     CDS             complement(12880..14229)
                     /locus_tag="ctg31_44"
                     /transl_table=11
                     /translation="MGKTLYLECYSGISGDMTVAALLDLGADRSVLDRVLKSLKVSGFE
                     TKISRVVKSGIDACDFDVVLDKEHENHDHDMEYLHGHHHEGHESNHAHGTGTAQDHHHH
                     EHRGIKEITYIIEHSAMTENAKKIALRIFEILAEAESKAHNVPVDQVHFHEVGAVDSIV
                     DIVSVAVCLDNLDVTEVIVPVLCEGRGTVRCQHGILPIPVPAVANIVSANHLHLKMTEV
                     EGELVTPTGAAIVAAVKTKDKLPETFEIQKIGIGAGKRQYECPGILRAMIISQSAEIDE
                     EKAQTEEFKNAEIGNNPKAENQETKDTIIKMETNIDDCSGEVLGFVMERLMKAGARDVH
                     YVPVFMKKNRPAWVLNVICKEEDIETLQNIIFEETTTIGIRYSIMERTILPRETRTLPT
                     PWGEVQVKVCTLNGKEQLYPEYESVAQLSREKEIPFTEIYRYIVLANKEK"
     CDS             complement(14232..14993)
                     /locus_tag="ctg31_45"
                     /transl_table=11
                     /translation="MTLQEILESVKSGSVSVEEAERILKKESYEEMGYAKLDTSRKART
                     GFAEVIYCSNKADEHLLNIFERLYREDGEVFGTRASQHQYELVKEKFPETEYDPISRIL
                     KVEKKDKKRIGKIAVCSAGTADIPVAEEAAQTAEYFGTNVERIYDVGVSGMHRLFSRLE
                     TIQSANCVIAVAGMEGALASVMGGLVSRPVIAVPTSVGYGASMHGLSALLTMINSCANG
                     IAVVNIDNGYGAGYLATQINRLAAGTDEKGN"
     CDS             complement(14971..15105)
                     /locus_tag="ctg31_46"
                     /transl_table=11
                     /translation="MITAKSSFVEEKYAAQYYSGNGCLYVSGAGGVLKGGIHDLTGNS"
     CDS             complement(15102..16286)
                     /locus_tag="ctg31_47"
                     /transl_table=11
                     /translation="MNTISVEELEKIDSSKITIVDVRPADQYSRGSFPGAVNIPLDEFE
                     ERMESVDREKMVYVLCHTGDRSRDCVEKLSDAGYEAVNIEGGYRAYLRLSLSRFMENDA
                     KEQKELKTKEIEHSIIKTFRKTVWRPFTKALNEYQLIQEGDKIAVCISGGKDSMLMAKL
                     LQELKRHGKIHFELVFLVMNPGYNADNWKIIQDNAELLGIPLTVFESDIFDTVAEIENN
                     PCYLCARMRRGYLYSHAKELGCNKIALGHHFDDVIETILMGMLYSGKVETMMPKLHSQN
                     FEGMELIRPMYLIKESAIKAWRDTNGLHFIQCACRFTENCVSCGGGRGSKRDEMKELVA
                     QFRNTSSVIETNIFNSVRDINLRTVMGYHKDGEYYNFLDDYDQRGNKGVDKDKE"
     CDS             complement(16619..18019)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210:glycerol kinase (Score: 167.4; E-value: 7.5e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_48"
                     /transl_table=11
                     /translation="MAAYYLAVDIGASSGRHILGHMENGKMVLEEIYRFENGMVKKDGE
                     LCWEFDRLFKEVVNGLKKCKEIGKIPVSMGVDTWGVDFVLLDKNDNVLGNTVGYRDHRT
                     EGMDKEVYKAISLKDLYARTGIQKADYNTIYQLMAVKKKHPEYLEQAETLLHVPDYFHF
                     LLTGQKTCEYTEATTGQLVSPITKDWDYELIDMLGYPRKMFQKLIMPGTGIGHLSDKIR
                     EEVGFDLEVVAPATHDTGSAVLAVPANDDDFIYISSGTWSLMGIERKEADCSEKSCEMN
                     FTNEGGYAGRFRYLKNIMGLWMIQSVRHEVNDAYSFAEICAMAEEAKDFPSRVDANDEC
                     FLSPDNMTEEVKDYCRRTGQKVPETLGEIATVIYTSLAECYAKTAKELEEMTGRTYSRI
                     HIVGGGSNAGYLNELTAKATKKEIHAGPGEATAIGNITAQMLKAEEFKTIEEARTIIHE
                     SFGVKVYK"
     CDS             complement(18322..18450)
                     /locus_tag="ctg31_49"
                     /transl_table=11
                     /translation="MYAIYALTAAANGQELEDVPTDGYWYDSTNMDSEEIAPNLYD"
ORIGIN
        1 catcaaagac aacttcatgg acaatgaaga aacatctgga ttcgttctcg gcgcaaaggt
       61 aaaaggactt gcaaataatc cggaagatta caaacgcttc tatcacaatg taaacggtca
      121 gaagatccgc cacgacaagg tacataacct gtttggctat aacatgaccc gtgcagcagg
      181 tgaagcattt gaaaaaatcg cacctggcaa acgttttctg atgttctccc gttcctccta
      241 tgtgggaatg cacagatacg gtggaatctg gatgggagac aacaaatcct ggtggtcaca
      301 catccttctg aacttaaaga tgcttccatc cctgaatatg tgcggtttcc tttacacagg
      361 tgcagatctg ggcggtttcg gtgcagatac cacacgtgac ctggtactgc gctggctggc
      421 acttggtgta ttcacacctc ttatgagaaa ccactccgct ctgggaacca gagaacagga
      481 agcttaccag tttgaaaata tcgaagactt ccgccatgtg atcggtgtca gatatcgcct
      541 tgttccatat ctgtacagtg aatacatgaa agcagcatta aacgacgaca tgatgttccg
      601 tccgctggca tttgactaca cagacgatgc attcgcaact caggtagagg accagcttct
      661 ccttggaaac gaaatcatga tcgcacctgt ttatacacag aatgcaaaag gccgctatgt
      721 atatctgcca gaagaaatga tgttcgtaaa attcctgcct gacggaacaa tttctcagga
      781 gattcttgaa aaaggacatc actatgtaga agttgccctg aatgaagttc cactgtttat
      841 tcgcaaagga aaagcaatcc cggttgctga tgttgcgcag acagtaaagg atatcgatcc
      901 ttctactatc cgcatgatcg gatatgaggg agctgaatat gaccgttatg atgatgacgg
      961 agtaagtgct ctgtaattta accaaattaa tcagatttat ctgcctcaat tacaggaatt
     1021 accagacagc agttagaatt gaacgagatg tcacctcata aaaaataaaa agaaacagtc
     1081 acatgtatcc aatgaatatc aatatattct ttcagttatg tgactgtttt cttttaattt
     1141 atcaattctc caaaagaacc tggttttgcc ggaacaaaat ttccaccttc atcaattgtt
     1201 ccaaattttt cttgatattc tccttcagta cgcgaaattt taggttttta ttctctttag
     1261 cagattctac tcatggggag aacatactca tacccattgt atccatggaa gccatactta
     1321 cgctgtaggg ctttctatcc tccccataga aacgcttctc cgaagaagtg ggcaaaccta
     1381 taacataaga agtaacatac ttacttaatt ccgttaaaaa ttaatacgta ttccatgcag
     1441 gaacatcgga atcacctcca acataatagg attatctttt tcaatcatct tcaatcactt
     1501 tgttcagcat caaaatatct attttcctcc atacctcgtt tccagctatt ccatcaattg
     1561 ttaatccttc ttctttctga aagttcttta ttgcttccgt tagttcttca tttgattttg
     1621 taacagagtt tccattgtaa tattgtaatt tttccaaaca tttttttaac aacttcatat
     1681 catcattttc tgttacaaaa tatgtctcat tattttctgt atttatcaca gcaacaactt
     1741 ccgtaaataa tgaatcaccc tccctgatat tttccgggtc aaaaggcaaa atcggaatat
     1801 tttctaaaga tccatattca aaatataatt cattcaataa atgaatactt ttctgaaatt
     1861 tctcctgctg tttcaattct tcttccgtat agttttcaaa aaataaagta ttataataat
     1921 ataatacttt attcatttta tctacatcat ccggattctc tttttccagt tgatccatcg
     1981 tccctgtttc acgagcccac acattattca aacaaatact acaaataaag ataatcatca
     2041 ataacactgc gtttttgctt ctgctatgtt tcatttgata cttctccttt cttcagatac
     2101 atttcagttc ttcttactta tatttaaatg ataacacatt cgtcgcaaaa ttttatgaaa
     2161 cagcgaaatt catatataaa ttggcgaaat tcgttttttc aaaacatagt gtgtttttta
     2221 taaggttttt tgccacaatt cctctccaat atttctgtaa tgttgcacaa acagtaaaag
     2281 atattgaacc cgcttttatc tgcatgatca gatatgagga agctaaatat agccgttata
     2341 atagcgacag tataagtatg ctgtaatcat ctgcccaaaa cagttacctc aaaaatagca
     2401 ataaaaagaa acagtcactt acatctgatg aattaagata ttcactcaaa tatgtgactg
     2461 ttttcttttt gaaatctgtt ttattacagc ttcacaatca ttgtattttc ctttttaaaa
     2521 actatttctc ccaatgaact taaaagtgct acattaaccc cttcatattt ttgatattca
     2581 cagcttccaa taaaaatata attcacctca tatttatcaa gcagttcctg tacttctttt
     2641 ttatctgttg aagtataaat agtttccacg tctgttcttc ttttgttttc ttcatcaaga
     2701 ttatttcgcc ataaccattc atgaacatac catcccaata ccgtcggcaa tcctgtcata
     2761 gcagaaaccc ggttgtcata gtctttataa ctgtcgccgc aagcttcaag aacagttggc
     2821 tgacctgtta tatttttatt cagccatcgt attgctgccg catcttcagg aatggcattt
     2881 tctagataag cagttgcatt gagagtttgg tatttatttt tcagaggaaa acctgtaaac
     2941 caatttgttg tagcatttat gaaatatcca caggtagata taagaagtat tattgccatt
     3001 cccccaacgg ttatctgcac ttttgataat cttacctttt tctcatatct attatccaat
     3061 ttagtttctt gcaaaatttt tattctgtct gccacaaaaa ataccagaat atacgacatc
     3121 ataagcgcaa aaagtatata tgcctgataa gtcaacttaa acatagtatt tgctcttggt
     3181 gctgtttttt catagatatc tcttacataa atgatttccg gaatcaatat tagtcccatt
     3241 gcacaaagag aaagtacaac tccgtataaa tcagaaacat taattttgta aaataaattc
     3301 ctgttttttt tatttgtaaa attcctattt tttatcagcg tagatacgac aaataatcca
     3361 catataagca atggaaaagc ccataataca caaaactgat aaaacgccgt atgaattttc
     3421 actattccga ttccctgtac cataacactt ttaaactgta aatggaatgg taacgaaatc
     3481 aacaccgcag tcagcagaag ttctatccat tgcacaacgc tccattttat accggttctc
     3541 atatctgaag gtttgatatc tgtagaatta agatatctct tcaaatttcc aaaaaacagt
     3601 gttccacata ttacaacata ataaatcata aaatcccatg tatttgaaaa caggaaaatt
     3661 ccaaggaaca gtcccagcag aaatatctct ttctgtttcc agcttttacc ggaatttctt
     3721 tttatccatg catataaaat ccccaatact gccaaaacaa aaaacacatt aatcacatgc
     3781 gcatgtaaat ccccaagaac aaaagaatat gaaggaaatt catgaattgt ctcgtcccct
     3841 gtcacaggtg gatcaaatcc tataaatcgt gttgtgcttg gaaaccagta atcttctctt
     3901 atccccagta atgtaaaaat ttttccatat ataatataat gaaggtttcc actcatggat
     3961 acagataaac ctgctaaaat acctccaaaa tctgttatcc atgctcttcc ccttttacct
     4021 aatttatcct taagcatctg acgcacaaga ctaaatggca atacaaacgc aaatgcagct
     4081 atcatggtac gcataagatt gtatgtaatc tctacctttg ttcctgtaag tttcgtaaga
     4141 aacaccgcaa aatattgacc accataatag tagttaaaag ctttgccagc ataccacata
     4201 tcttctgacg gaagtgttgt gctacgcatc atagacttca taaaaccaaa atccatatat
     4261 ttttcagttc catgagctgc cggatgaaat cctgccatat atgtccacaa aagaaataca
     4321 acaaagaaaa tcacttcttc ccaataaaca agttccatat gtttccacag aaaaaccttt
     4381 ctttgttttc catatattcc ataagcaata ctgctccccc cacataaggt agtaattacg
     4441 atagaactca atgtggtaaa gtgaaccact tttatagaag tcaaaatcca tactccatat
     4501 ccgcatatca ctattgctat aacctttgaa tacatccatc cattatcatc aaaacctttg
     4561 aatatctgag ccgttatcgg cataaatacc aatccaagaa tccataaaat ttcccaccat
     4621 atcatgaatg taaagaaatc ggatcctaac agccaaaaag caactcctat caatagccct
     4681 gctgccagta atttaaattt atttactttt ttcataataa tatatttctc cataattttt
     4741 tttataatta agcaaaaata taccagtcac ttcatcatat aagctacaat agctctatat
     4801 ctttttttgc atcatttgta tttgaataat atcatattta ttgcaaaatt ttctaaaatg
     4861 gcgaaattca tatataaatt ggcgaaattc gtttttcgag aacatattgt ggttttttat
     4921 gatgttttct gtcacaatat tttccctctt gactaatttt ctgcaaaata aaagacagcg
     4981 cagtcctacc actacactat ctttcataga ttctacataa tttataagta cagcattacc
     5041 tttacagtaa aaatctgatt tgtattcgaa acatccataa atccctgata tttctctacc
     5101 atcttcctga catttgcaag accaatgcca tgtccttttt cttccttcgt tgacaataat
     5161 ttatttttct ctacagccaa ttcatgttga aagctgtttt ttatttccat ggaaagcatg
     5221 cccttttcat agtatatatc cactgacatc catttatctt tcgtctgttc tgctgcttct
     5281 attgcgttct ctgtcaggtt tcccaaaatc acattcagat caaatgctga tatacacaaa
     5341 tcagatggta cccgtacctc atactctaca tgattcagtt tcttttttgc ctgtcccaga
     5401 agataattca gcagactgtc aagattctta ttcccacagc tgaccagttc agactggttc
     5461 tgcatatact cccccatgtc ctgtatatat ttccaaattt cttcattatt ctgatttcca
     5521 gccataagtg caagttctcc cagatgattt ttcaggtcat ggcgtagagc ttttactttc
     5581 tcttccgatt gcatcaacac atccaactgg tgagaataaa tgagcatttg tttttccata
     5641 agagattgtt cttccagttt cttatacgca cttatcagaa catcatataa atagaaaatc
     5701 aataatacaa ctgccaaaac acaacatcca aataacacca gcaggatacg attttttagt
     5761 tcctgttcaa caataagcaa ttctgccaga caaagtgctg aaataaccgc cagtatcatc
     5821 ccatgcggag ttttatcttc tcctttattc ttaatcaaga ttttttctga aataacatcg
     5881 caaatcagca ataatagtac agttatatac gcagcacatt caccgacttt ccctgttatt
     5941 gaataatctg tcagtaaatg aacagctact aaatcacatc ccatattagt tccatataca
     6001 agtagtgtca caaatatttt ctttttcaat gctccttcat aacacactgt aatcaaaaaa
     6061 atcagcacta tatttgttat cacactcata cctggcgaac aaaatatcag atgtaccact
     6121 gctgtcaaaa caaaaaacaa tacataacag gctctttctt ttttcttttc ctcaatatct
     6181 gtccaaaaga acaacctcat aaagcgatag attatatatg tacgcaaaag attcgtgctt
     6241 aatgtagtta tcaacgcaaa catttactct ctgtccctcc acacacgttc cgccagttgc
     6301 tttctcactg atttccgata tggctggctg atcggaattg tatctccgtt tttcattttc
     6361 acagattcat aagaacattc ttcgatataa tcaaaattga tcaggtacga ctgatgaatc
     6421 tgaatgaaat ttcccggaat tttctttgct atttctttca gtttgccatt aaattctact
     6481 actttgaaat caagcaggaa gatggaaaca aaaagtatgg aaaaagcaaa gaacacagac
     6541 caaatccgat cattcaaatg gatatgttta tggatggcga cggcatccct cttgcatttt
     6601 ctacctttgc agaaaatgta aacgaacaga catccctcaa accattggaa aaaaagatac
     6661 ttggagagtt tggatgccag aaatttattt actgcagtga tgcagacctg ggttccgaat
     6721 ctatccgtga atacaaccat atgggggaac gtgcttatat cgtaactcag tccattaaaa
     6781 aactaaaaaa agaagaaaaa gaatgggcat tagatccaca gggatttaaa aaagtatccg
     6841 atgacactcc tgttgatatc actaagctca atagtaatga caaaggtctt tattacaaag
     6901 atgaacctta taccacgaaa aagctacacc agcgtctgat cattacttat tcaccgaaat
     6961 atgcagctta tcaaagaaca atccgtgata aacaagtgga acgtgcacaa aaaatgctgg
     7021 attcagggaa tacaaaaaag aaccgtaaaa accccaatga tccggcacgt tttatcgaaa
     7081 agacagcagt tacgccagaa ggagaagcgg ctgatatcaa atattccctg gatgaaaaca
     7141 agattactga agaaactctg tatgatgggc tttacgcagt atgtaccgat cttcttgatg
     7201 ataatgttgc taatattttg aaggtaagtg aaggacggtg gcagatagaa gaatcccgtc
     7261 tttgacagtt tgtaaaagaa aaaaacgctg caacccttgt atttactggg ctgtggcgat
     7321 ttttctcatc atcacgaagt atggtaattt attcttttct tttacttttt tctggatttt
     7381 tttcattctg cttttcgtta taaattgata atccgttcga aagccccagg cttcatgaag
     7441 atcatcagta atagcttccc gtttctataa aggtataaat ccctgttcct ggatctctgc
     7501 aaaattcatt gcttttaatg tatctaatga ttcctcacaa gtatatttat agttcaattt
     7561 tctcccaaag aaacgataga tcattaatgc cagaaaacag atcagaaaat gtgctttgat
     7621 ccgtttttca tcccgcagat aaacaggtct tgcggaaaag tctgttttca tgatccggaa
     7681 acattcttcg atctgccatc ttccttcact tacttttaaa atatcgctga cttcatcgtc
     7741 tgacaggttc gtgcatactg cataaagtcc atcatactgg ctttcttcag agatcttatg
     7801 ttcattaaga taatgccgga tatcggcagt ctcactttct tttgttactg ctgctgttcc
     7861 aataaatctg gctgaattgt ttgggttcct gcggttcttt tttgtgttcc cggaatccag
     7921 catcgcttgt gcacgttcta tctgtttgct acgaatggat ttctggtaaa gggcatattt
     7981 aggggaataa gtaatgatca aacgctgctg taacttttta gtggtatatg gctcatcttt
     8041 gtaataaagt cctttgtcgt cctcgggcag ttttgagata tcaacagttt tatcatcaga
     8101 tacccttttg aatccctgcg ggcttaaaac ccattccttc tctccttttt tcagcttttt
     8161 aataaacgtg gtcacaatat aggtccgttc ccccatatgg ttatattccc tgataaattc
     8221 gaatcccaga cctgcatcgc tgcagtaaat aaatttctga tattcaaaat cttcgaggat
     8281 tttttgctct aatggtttca gcgatgtctg ttcgtttgaa ttccctgaaa agagggagaa
     8341 agcaaggagc cctatgggtc ccttttactc aaaacaaaag aggctgtcat ttaacaatga
     8401 tttccaacat cgtcagctcc aaataaaact atcccggcaa gtacaagact tttattcttt
     8461 gtagcttgtt cgggatagtt ttattttaag aaacaaattt tatttttgaa cgaaaaaact
     8521 tatctgaaat tttgcatcca tattcgatta aatccatatt cttctttctt attttctgat
     8581 cgcattcata caatatttat aaattctttt ataggtacgt gtagaatagt gaacgccgtc
     8641 atctatattt cccttaaact cattgtatgt actgtaaccg tttttcatca gatatttata
     8701 ggtatctatc cattgaaatc tcttatttaa cctgctctgc aatctgtcat taaagtaacg
     8761 taactgcgct tcttttcggg ttggtttcat tgctgtattt accggattca cagacatata
     8821 aaacaatctg cagtcacttt caagttcctc tgcaagagtg ttcatacgcg caagatatgc
     8881 atttgcctcg cctttataat caaccccatt cccggaatta tgactcgaaa gatcattcac
     8941 accaagatta aaaataactg ctacgggctt atctgaatct gactgcagac gggcaatttc
     9001 acttctcatt actctctctc ctgctgtctc aaaccagctc agtccctccc ctgtcttaca
     9061 cacaaatgat acttttgcaa ctgcatcctt tccatattcc tgaagaagag ttttctgcat
     9121 aaaatacgtt ctggaatctc ccacaaaaat aattccggaa tactccgaca gctgagctgc
     9181 cagattattg acctgaatat ccggctcctg ttgccagtta tacataactg catataaatg
     9241 ggttttcttc cttacctgta tcacctgtcc cgcctgatac tgcggattct gagtctgatc
     9301 cggcttcgtg ctccatccaa gaaaagtata tccggtctcg ttctttattg caggaagtgt
     9361 cacttttcca ttactgtctg cttttcttgt tgtcgtagac ccatctgcct gatggaaaat
     9421 aaccgccttc tgagaagcag atgaaatcgc tcctgttccc tccgacggag ccagtgactc
     9481 atccttttta ttatccgaat atgtaaaaga tgtgaagctt gtggttcctt tttccgcatc
     9541 gtaaaccctt actttgctgg ttttcgcaaa agctgtttca caaaaacacg aactgaaaca
     9601 aatcattcct gtcaacatta caaaaaacaa tttttttacc ataatattta tctccttaca
     9661 caaacagttt ctcccggata ttttccgagc agaagctgtt tttttattat taatcatcta
     9721 taagatttaa caaaattata taaataattc ccaaatcttg ttcctatatt tacactaaaa
     9781 tccagtctcc tatccattgt tttgttgtac aattatataa acgtttatac atctttccgt
     9841 ttatgatttt atatttgcag actgtttaat acaaaatttt ttatttttcc tacaatcaca
     9901 catcctccaa cagtcagatt tgttactcca actgtaatgg ctatgcttct tatcgcggta
     9961 aaattcaaaa agatacatag cacatacata caccctattc tcactcttgc ttttttccat
    10021 atttttcttt ttcccaatat tccagacgat gattcttatt gtccactgga acaagaaaat
    10081 acagaagaat aaaattcaga ctttgcagaa gaataaaaat ctcattatca ctaccatcag
    10141 acatatagcg gattgccaat aatgcaactg caataattgc tgttgaaatc acatagcacc
    10201 gattttgtgt atctgcatga taaccaccgg catatttcct taaagcaata aagcatacaa
    10261 gaaaaattat gctttgaaaa aacacctgaa agatacatcc catcagtaat gtcacaaatg
    10321 tcatagtgca gatacttttt attctgtcaa gtccatagcg aataatttcc tctttttctt
    10381 cctttgaaaa agtttgtgtt tccatatcaa tgttttctta atttttttgc agtttctggt
    10441 actttaggct gatatgtaag ccaggagcat gtttcattta catttgaagc agcagcttta
    10501 aatgcaattc tttcaatgac ttttttcaat tcctttctcg tttcttgtta tcctcccttc
    10561 ggatatattt catttcttct taccttgtat ttgaataata acatatttat cgcaaaattt
    10621 tctaaaatgg cgaaattcat atataaattg gcgaaattcg ttttttcaga acatattgtg
    10681 gttttttata aggttttctg tcacaatatt ttccctcttg actaattttc tgcaaaataa
    10741 aagacagcgc agtcctacca ctacactatc tttcatagat tctacataat ttataagtac
    10801 agcattacct ttacagtaaa aatctgattt gtattcgaaa catccataaa tccctgatat
    10861 ttctctacca tcttcctgac atttgcaaga ccaatgccat gtcctttttc ttccttcgtt
    10921 gacaataatt tatttttctc tacagccaat tcatgttgaa agctgttttt tatttccatg
    10981 gaaagcatgc ccttttcata gtatatatcc actgacatcc atttatcttt cgtctgttct
    11041 gctgcttcta ttgcgttctc tgtcaggttt cccaaaatca cattcagatc aaatgctgat
    11101 atacacaaat cagatggtac ccgtacctca tactctacat gattcagttt cttttttgcc
    11161 tgtcccagaa gataattcag cagactgtca agattcttat tcccacagct gaccagttca
    11221 gactggttct gcatatactc ccccatgtcc tgtatatatt tccaaatttc ttcattattc
    11281 tgatttccag ccataagtgc aagttctccc agatgatttt tcaggtcatg gcgtagagct
    11341 tttactttct cttccgattg catcaacaca tccaactggt gagaataaat gagcatttgt
    11401 ttttccataa gagattgttc ttccagtttc ttatacgcac ttatcagaac atcatataaa
    11461 tagaaaatca ataatacaac tgccaaaaca caacatccaa ataacaccag caggatacga
    11521 ttttttagtt cctgttcaac aataagcaat tctgccagac aaagtgctga aataaccgcc
    11581 agtatcatcc catgcggagt tttatcttct cctttattct taatcaagat tttttctgaa
    11641 ataacatcgc aaatcagcaa taatagtaca gttatatacg cagcacattc accgactttc
    11701 cctgttattg aataatctgt cagtaaatga acagctacta aatcacatcc catattagtt
    11761 ccatatacaa gtagtgtcac aaatattttc tttttcaatg ctccttcata acacactgta
    11821 atcaaaaaaa tcagcactat atttgttatc acactcatac ctggcgaaca aaatatcaga
    11881 tgtaccactg ctgtcaaaac aaaaaacaat acataacagg ctctttcttt tttcttttcc
    11941 tcaatatctg tccaaaagaa caacctcata aagcgataga ttatatatgt acgcaaaaga
    12001 ttcgtgctta atgtagttat caacgcaaac atttactctc tgtccctcca cacacgttcc
    12061 gccagttgct ttctcactga tttccgatat ggctggctga tcggaattgt atctccgttt
    12121 ttcattttca cagattcata agaacattct tcgatataat caaaattgat caggtacgac
    12181 tgatgaatct gaatgaaatt tcccggaatt ttctttgcta tttctttcag tttgccatta
    12241 aattctttct gtccgtcttt taaaaccaga tgcacttttt tattctgact gctgaaatac
    12301 agaatatctt tatacagcac cttgaaataa tatccactgc caaagtactc gaaaatacct
    12361 tttctgactt ccgaaatttt ctgaatcctg ttcatgacat tcccaacttt tattttgtct
    12421 aaaggtttga tcagaaaatc tgtaggctgt acacgaaata gatccatcgc ataactgctg
    12481 ttcgctgaaa tgtaaacaat tgcagtttcc atgttttcct gttcttctct tataaaacgt
    12541 cccacttcaa ttccatttgt tgtcagtaat tctatatcca gaaataacac atcaagaatc
    12601 ttcttgtttt ctctcaggaa ccggcacagg ctttctccct gataccagat atcaatattc
    12661 atctgaattt tatgctcttt tccataatca taaagcattt tttccagttc cccgcagaga
    12721 ccctcatcat catcgcaaat gccaatgcaa aacattcctt ttctcccttc atactacatg
    12781 cagtatacag ctcttacaac tctatttcaa gacaaaagta ccctttgatt tcgcgtggag
    12841 tactctcagg gaaaccaaag ggttcacata tgaaagttat tatttttctt tatttgccaa
    12901 aacaatataa cggtaaattt ctgtaaacgg gatctctttt tctctgctca actgtgcaac
    12961 gctctcatat tccggataaa gctgctcttt tccattcaaa gtgcatacct ttacctgaac
    13021 ttctccccat ggagtcggaa gggttctcgt ttctctggga agaatcgtac gttccattat
    13081 gctataacga attccaatcg tagtagtttc ttcaaaaata atattctgaa gcgtttctat
    13141 atcttcttcc ttacagatta cattcagaac ccatgcaggt ctgttttttt tcataaaaac
    13201 aggcacataa tgcacatctc tggcaccggc tttcatcaga cgttccatga caaatcccag
    13261 aacttctcca ctgcagtcat caatgtttgt ctccatcttg ataatcgtat ctttggtttc
    13321 ctgattttca gctttcggat tatttccgat ttccgcgttt ttgaattctt ctgtctgagc
    13381 cttttcttca tctatttctg cgctctgtga gataatcatt gcccttagga ttcccggaca
    13441 ctcatactgg cgtttacctg caccgattcc aatcttctgg atttcaaatg tttccggaag
    13501 tttatccttt gtttttactg ctgccactat cgccgcacct gtaggcgtta caagttcacc
    13561 ttctacctct gtcattttca gatgtaaatg attggcactt actatatttg caactgccgg
    13621 aaccgggatt ggcaggatgc catgctgaca acggacagtt ccacgtccct cgcagagaac
    13681 aggaacgatc acctctgtaa catccagatt atccaggcag actgccacag acacaatatc
    13741 cacaatagag tccactgctc ccacctcatg aaaatgcacc tgatccacag gcacattgtg
    13801 tgctttactc tctgcctctg caagaatttc aaatatacgc aatgcgatct tctttgcatt
    13861 ctcagtcatt gcgctatgct ctataatata ggtaatttct tttattccac ggtgctcgtg
    13921 atggtgatgg tcttgcgctg ttcctgtgcc atgggcgtga ttgctctcat ggccttcatg
    13981 atgatgtcca tgcagatatt ccatatcatg gtcatgattt tcatgctctt tatccagcac
    14041 aacatcaaaa tcacatgcat ctattccgga cttcacaact ctgctgatct ttgtctcaaa
    14101 tcctgatacc ttaagactct tcagcaccct gtccagcact gagcggtcag ctcccagatc
    14161 aagaagagcc gcaaccgtca tatcaccact tatccctgaa taacattcca gatataatgt
    14221 tttccccata atcaatttcc tttctcatct gtacctgctg ccagacggtt gatctgtgtt
    14281 gccagatagc cggcaccgta gccgttatca atattcacca cagcaatccc attcgcacag
    14341 gaattgatca tggtaagaag tgccgaaaga ccatgcatac ttgcaccata acccacagaa
    14401 gtcggtactg cgattaccgg tctgctcacc agaccgccca tcacactggc aagagctccc
    14461 tccattcccg caactgcaat tacacagttc gcactctgga ttgtctccag tctggaaaat
    14521 aaacgatgca ttccgctgac tcccacatca taaatccgtt caacatttgt accaaaatat
    14581 tccgctgtct gtgcagcttc ctcagcaacc ggaatatctg cagttcctgc tgaacacacg
    14641 gcgatcttac caatacgctt cttatctttc ttttcaacct ttaagatgcg tgagatcgga
    14701 tcatattctg tttccggaaa cttctctttc accagttcat actgatgttg ggaagctctg
    14761 gttccaaata cctcgccgtc ttctctgtat aatctttcaa aaatattcag aagatgttca
    14821 tctgccttat tactgcagta gattacttct gcgaaaccgg ttcttgcctt gcggcttgta
    14881 tccagcttcg catatcccat ttcttcataa ctttctttct taaggattct ctctgcctct
    14941 tctacagata cagaaccact ttttacactt tcaagaattt cctgtaaggt catggattcc
    15001 tccttttaga acaccacctg caccagaaac atacagacaa ccgttcccac tataatactg
    15061 agcagcgtat ttctcttcca caaatgaaga ttttgctgtt atcattcttt atccttatca
    15121 acgcccttat ttccacgctg atcatagtca tccaggaaat tataatattc tccatcttta
    15181 tgatatccca taacagtacg aagattaata tcccgcacac tgttaaagat attcgtctcg
    15241 atcacactac ttgtatttct aaactgtgca accaactctt tcatctcatc acgcttggaa
    15301 ccacgtccgc ccccacagct tacacagttc tcggtgaaac ggcatgcaca ctgaatgaag
    15361 tgcaacccat tagtatctct ccatgccttg atcgcagatt ccttgatcag atacatggga
    15421 cggatcagtt ccattccctc aaaattctga ctgtgcagct tcggcatcat agtctccacc
    15481 ttaccactgt acagcatacc catgaggatt gtctcgatca catcatcaaa atgatgtccc
    15541 agcgcaatct tattacatcc cagctccttg gcatgagaat acagataacc acgtctcatt
    15601 ctcgcacaaa gataacaggg attattctca atttctgcca ctgtatcaaa aatatcactt
    15661 tcaaaaaccg taagaggaat tcccagaagc tctgcattat cctgaataat cttccagtta
    15721 tccgcattat agcccggatt cattaccaga aacaccagtt caaaatgaat cttcccatgg
    15781 cgcttcagct cctgaagcag cttcgccatc aacatagagt ccttaccacc tgaaatacag
    15841 acagcaatct tatctccctc ctgaatcagc tgatactcat tcaaagcctt ggtaaacggt
    15901 ctccagaccg tctttctgaa cgtcttgata atactgtgct caatctcttt cgtcttcagt
    15961 tccttctgct ccttagcatc attctccata aaacggctca gagaaagtct cagatacgca
    16021 cgatatccac cttcaatatt cacagcctca taccctgcat cactcagctt ctccacacaa
    16081 tcccggcttc tgtcccccgt atgacagaga acatacacca tcttctccct gtccacagac
    16141 tccattcttt cctcaaactc atccagcgga atattcactg cccccggaaa agatcccctg
    16201 ctgtactgat ccgccggccg cacatccacg atcgtaatct tagaagaatc aatcttctcc
    16261 agctcttcca cactaattgt attcatatat aacctgcctt tatctattaa aatcaatcac
    16321 ttacctctga tgaatcaccc tgtatttccg cccaattcac cagccatcat tatactttga
    16381 aaccccatga tagtcaacat attccctcgc cgttgactcc tttctcacag ccacagttac
    16441 tgttcactcc gttcacagta acgaatgatt ttccaaacac cttttaacct cattatatac
    16501 gattcatttt tttcagacaa ccttctcaga tatataaaat taaaacctcc cggttgaaat
    16561 ttttttctta ttatcgcaga cacaaaagga acagagccaa cgccctgttc cctttttatt
    16621 atttataaac ttttacacca aaggattcat gaatgatagt acgagcctct tcaatggttt
    16681 taaactcttc tgctttcagc atctgtgctg tgatatttcc gattgcagtt gcctctcctg
    16741 gacctgcatg gatttctttc tttgttgcct ttgcagtcag ctcattgaga tatcctgcgt
    16801 tggaaccgcc gcccacgata tgaatacggc tgtaagtcct gcctgtcatc tcttccagct
    16861 cttttgctgt ctttgcatag cattccgcaa gacttgtgta gataactgtt gcaatctctc
    16921 ccagagtttc cggaaccttc tgtcctgttc tgcggcagta atccttaact tcctctgtca
    16981 tattgtcagg agaaaggaaa cactcatcat ttgcgtctac tcttgacggg aaatcctttg
    17041 cttcctctgc cattgcgcag atttctgcaa agctgtatgc atcatttact tcatgacgca
    17101 cagactggat catccagagt cccatgatat tcttcaggta acggaaacgg cctgcataac
    17161 cgccttcatt tgtgaagttc atctcacagc tcttctcaga gcagtcagct tcttttctct
    17221 caattcccat cagtgaccat gttccggagc tgatgtagat aaaatcatcg tcatttgcag
    17281 gaactgccag tacagcggat cctgtatcat gtgttgcagg tgcaaccact tccagatcaa
    17341 agcccacttc ttctctgatc ttatctgaca aatgtccgat gcctgttccg ggcatgatca
    17401 gcttctgaaa catttttctc ggataaccga gcatatcgat cagttcataa tcccagtcct
    17461 tagtaatcgg gcttacaagc tgtcctgtcg tagcttctgt gtactcacag gttttctgtc
    17521 ctgtaagaag gaaatggaaa taatccggca catgaagaag tgtctccgcc tgttccagat
    17581 attccggatg tttctttttc actgccatca gctgatagat cgtattataa tcagctttct
    17641 ggatacctgt tcttgcatag agatctttca gggaaattgc cttataaact tctttatcca
    17701 ttccctctgt acggtggtca cgatatccta ctgtatttcc aagaacattg tcatttttgt
    17761 ccagaagtac gaagtcaacg ccccatgtgt ccacgcccat acttaccgga atcttgccga
    17821 tttctttaca tttcttcaga ccatttacta cctctttgaa aagacggtca aattcccagc
    17881 agagttctcc gtctttcttt accattccat tctcaaaacg ataaatttct tccagaacca
    17941 tttttccgtt ttccatatgt ccaaggatat gacgtccgct ggatgctccg atatctactg
    18001 ctaaataata tgctgccatt gcaaaacctc ctcaatatat gaatttatac gctcttcata
    18061 tctgatgatt tcattttatc tcaacttact cccccaaaat aagaaccttg tttgtctgaa
    18121 aaagtgtcct tatttgctat tttgaaatct atcgtcgaaa taagtatctt tacaacttaa
    18181 taaaatcatc atttccaatc attgttttat tgtttgaaca acaacgccgc acttgccata
    18241 cggcagtgcg gcgtctgtat ttgtattaat aattaatact taattctaag gattcatttc
    18301 ctctcgatat ttacttatcg attagtcata aaggttagga gcgatttctt cgctgtccat
    18361 gtttgtggaa tcataccagt atccatctgt aggaacatct tcaagttcct gtccgttagc
    18421 tgctgctgtc agagcgtaga ttgcatagta
//
