LOCUS       c00001_gnlPro..        15148 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DFDIIAHB_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:17:52
            Original ID  :: gnl|Prokka|DFDIIAHB_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15148
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15148
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1677:5148]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1678..5148
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15148
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15148
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(77..1492)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MNNLYTFAYMRKDLNGSRHFSIGIKFTILLFTIVILVLVLFSYRS
                     DKHGNLFWQVEKLIPHHPDSALVLLDKVRDINGLSLREKARYCLLWTESRDEAGLRHTS
                     DSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPSLALECYLRALEYEGENWDYEF
                     WGRLYNQMGMLYAEQELYGKAMSFLRKASAQYQLLNDAAGQDRILTEVKKYEMLRDSIG
                     SLSARESIYQITSRYDVRPIREDLSKKELMLLQRGQERYLYAFIIGIILFICFLLYRRW
                     RNTQENALRREEALRRSIASQQQRMREEKEENERQITLLEKRITKIKEEKDQELMLVSL
                     QLEKQRLEICNESILNKESKHLLSVAILRKSEVYEKFHDRDAGKIISEDWELLEVLLNK
                     AYDDFTLRLKKLYPVISDTELKACMLTKIGVPANQITRVLKYNSSVLRPRLFRKIFKKE
                     GSTEAFVEFISNF"
     CDS             1678..2370
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="SucD_FumR (E-value: 4.6e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             2419..4362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.1e-60, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.8e-38,
                     bitscore: 122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             4393..5148
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Fer2_3 (E-value: 5e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             5571..6782
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="Radical_SAM (E-value: 2.9e-16, bitscore:
                     51.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIVAIGHGYKANCW
                     CTHGCWITSSIIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             6816..8048
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNIDPDWTFKWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIDSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGLKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(8063..8155)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MKKPRCKYTELLLFVNSLSAKLCFVTCNKI"
     CDS             complement(8254..11343)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="LILCLIAGMPTPAYGSSSYPVKEESYVLVINSYVDGERWSGNLLN
                     MISKFATPEEYTLRIDHISVMLVDTPEKLKEKQEVFFEANKKKPDGIIYLGVNGWAFMR
                     DKIREKWGDIPTLVCSETGEMAENECYFNQRHSSDRVIPLQEAVKGYNATGLVIPYYVK
                     GSIDLVKELIPGLKRLIFISDRRYVSTWLRDEMEKHMETSFPEGKVDFYTEGSCSMDSL
                     LAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGISRHPVFSLYDMGVEEG
                     YTIGGYYNSAKTIETALIPLLQQVYNGEDMGKIPVSTVNDPHKYLNYASLISAISNEDN
                     FPRDAIYLNAPPSFLEKYWMQLLGFLIFFLVVVFLAWHYVYRSKQKMKEVELRLLSRYR
                     DLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFVVNKRGKEIANLIGGSY
                     PLLLSAVPTVLESGKSFTYEYYFEPTGLYYTIIIMPTSEENVVDAFFIDITDIHKFQTH
                     LKAMNHKLAMALEAADLLPWRYNLAEEKIIYESKVHPGDNIETAEVHTHEVSLKEYFSK
                     IHPSFRACVEKAFDDLCNGKIKKVRKEYCLERLIPGEDRHEWEEIQVMVEYDASGKPKA
                     LIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEIRTPLNAIVGFSNILAS
                     TDNLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTYDYVDINAVLRDLEQSA
                     HLKNKNPDVQISFKDYLEPCVIYTDRNRLSQLMINLLNNAMKFTQAGLISFGYKLRDDN
                     TLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICEMIVTQMKGTIGVDSME
                     GKGSKFWFTLPFQPKKELFPSEEQKPVTLEKIARSEVTILIAEDNSSNYRLFESILKPE
                     YKLIHAWNGKEAVELFYQHKPQLILMDIKMPVMDGYEATAEIRKVSASVPIIAVTAYAF
                     AQDEQRIINSGFDAYTAKPINGKILKDKISTLLTHRIILM"
     CDS             11631..12398
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MDMKDYDINFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPSLFD
                     LLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRVYWPLGLILL
                     GLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHIVLD
                     PVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVGSFLA
                     GCQDMRELTEATDMTHTLYICGDLSFSGLELRD"
     CDS             12406..13200
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLPLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGARIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             complement(13540..14064)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQM
                     LVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGSFINGEVFDDRSFEAG
                     EPAVMEVYKMTDGFATALQNMHPGDKWEIWVPSQLGYGEAGYKNPNTGAVVVKPCTTMI
                     FEMEVVGIVEE"
ORIGIN
        1 atatctcaca aatcacataa taaatgagaa caaaaatgag aacaaacctg ccaagaccgc
       61 tataaatata taataatcaa aagtttgata taaactccac aaatgcctcc gtagaacctt
      121 ctttcttaaa aatcttccgg aatagacgag gacgaagtac cgaactatta tatttcaata
      181 cccgtgtgat ctggttggcg ggaacaccga ttttcgtgag catacaggcc ttcaactccg
      241 tatcggaaat aacaggatat agctttttca gccgtaaggt aaagtcatca taagccttat
      301 tcaacaaaac ctccaaaagc tcccaatcct cagagataat cttgccggca tcccgatcgt
      361 gaaacttctc atagacctcc gatttccgca agatcgcgac agataataaa tgcttactct
      421 ccttattaag aatcgactcg ttacaaattt ccagccgttg tttttccaat tgtaaggaaa
      481 ccaacatcaa ctcttgatcc ttttcttcct ttattttcgt aattcttttt tccaaaaggg
      541 tgatttgccg ttcattctct tctttttctt ctcgcatacg ttgttgctgg ctagcaatcg
      601 aacgtcgcaa ggcttcttcc cttcgaagag cgttttcctg cgtatttctc catcgccgat
      661 aaaggaggaa gcaaataaat aggattatgc cgataataaa tgcgtacaga taacgctcct
      721 gtcccctttg taatagcatc aactctttct tagacaagtc ctcacggatc ggccttacat
      781 catagcggga agtgatctga taaatcgatt ctctcgctga tagtgatccg atagaatccc
      841 gtaacatctc gtatttcttg acctcggtca gtatccggtc ttgtccggcc gcatcgttca
      901 ataactgata ttgagcactc gcttttctca aaaaagacat agccttgcca tataattcct
      961 gctcggcgta cagcatcccc atttggttat ataaccttcc ccagaattca taatcccaat
     1021 tctctccctc atattccaac gcacgtaaat agcattccaa agctagggac ggttgatcca
     1081 tatcctcata gactttcccc cggtaaaacc aagctttggg aggccagtaa cagcctcgtg
     1141 tcgtcctata ataatccgta gcgatagaga ttatggaatc cgatgtatgc ctcaatcccg
     1201 cctcatcccg tgattcggtc cataacagac aataacgggc tttctctcga agcgataatc
     1261 cattgatatc cctcacttta tctaataaca ccaaagcact gtccggatga tgcggaatca
     1321 atttctctac ctgccagaac aggttgccat gcttgtcgct cctatatgaa aaaagcacaa
     1381 gaaccaagat cacgatcgta aataataaga tcgtaaactt gatccctatg gaaaaatgcc
     1441 gtgacccatt caaatcctta cgcatatagg caaatgtata taaattattc ataaggaaag
     1501 ccttttcctt ccgcattatt ccatgtgtcg ggacacatgc cctgacctct cccattaatg
     1561 cagaaatatt tctttaatcg tttgcgcaat atatggattt agcatacctt tgcgtgataa
     1621 ttacatagtt taagtagaaa tttctaaata caattaaata acttaaatta ttatcttatg
     1681 tggttactta attcttctat cgggaagaag ctgataatga gtatatcagg cctctttctt
     1741 gttctgttct tattgttcca cctgtcgatg aacgtggcgg ccgttttctc cggagaggct
     1801 tataacatgg tttgttcgct gttgggctct aattggtacg ctgtggcagc tactctcgta
     1861 ttggccgcag gcgttgtgat ccacttcgtg tacgctatca ttcttacctt gcaaaaccgt
     1921 aaggcacgtg gtaacgaccg ttacgctatc aacgctcgtc cgaaaggcgt ggaatgggca
     1981 tctcagaaca tgttcgtttt gggtttgatt gttatcctgt tcatgctgtt gcacttcagc
     2041 cagttctggt ataagatgat gttcgccgaa ttgatcggtc atcacgaagt tgcattgggg
     2101 tcagctatgg tatctccaca agacggagcc gcttttatca actattactt ccaaggtaat
     2161 gccgtgatca ctgttcttta tttgatctgg tacgtggctt tgtggttcca cttgactcac
     2221 gggttctgga gcgctatcca aacaattggt tggaataata cgatctggat gaaccgttgg
     2281 gaatgtatct ctaagatcgt agctacggtt atttgcggac ttttcgcgat cattactatc
     2341 atcttcttcc taaacggagt aggtgcttaa ttgcaagcta caggttttat aattaagaac
     2401 ttttgaaatt aaatcattat gtctgaaata aattctaaaa tacctcaagg cccgttggct
     2461 gagaagtgga ctaattataa aaatcaccag aaattggtga accccgctaa caagcgtcgt
     2521 ttggatgtta tcgtagtcgg tacaggtttg gccggagctt ccgctgccgc atctttggca
     2581 gagatgggat tcaacgtatt gaacttctgt atccaagatt ctccccgccg tgcgcactct
     2641 atcgccgctc aaggtggtat caacgccgct aagaactacc agaatgatgg tgactctgtt
     2701 taccgtttgt tctacgatac gatcaaaggt ggtgactacc gtgctcgtga ggctaacgtt
     2761 tatcgtttgg ctgaggtttc taactcaatc atcgaccagt gcgtggctca aggcgttcct
     2821 ttcgctcgcg aatatggtgg tttgttggat aaccgttcat tcggtggcgc tcaggtatcg
     2881 cgtacgttct acgcccgtgg ccagacgggt cagcagcttt tgttaggcgc ttattcagcg
     2941 ttgagccgtc agatcggttt gggtaaggtt aagatgtaca ctcgtcatga gatgttggat
     3001 gtagttaagg tagacggtcg tgctcgtggt atcatcgccc gcaacttgat tacaggtaag
     3061 atcgagcgtt acgccgctca cgctgtagtt gtagctacgg gtggttacgt taatacgttc
     3121 ttcttgtcaa ccaacgctat ggcatctaac ggttccgccg catggcaatg ctacaagaaa
     3181 ggcgcttact tcgctaatcc ttgtatggtt cagatccacc cgacttgcgt accggtgaaa
     3241 ggtgacttcc aatctaaatt gactttgatg tccgaatcct tgcgtaacga cggccgtatc
     3301 tgggttccga agaaactgga agacgctaaa gctctacagg ccggaacgaa gaaaggtaaa
     3361 gatattcccg aggcagaccg tgattattat ttggagcgtc gttatccggc attcggaaac
     3421 ttggttcctc gcgacgtggc ttctcgtgcc gctaaagagc gttgcgacgc aggtttcggc
     3481 gtgaacagca cgggcttggc cgtattcttg gatttctccg acgcgatcaa tcgcttgggt
     3541 aaagaggtcg ttaagcagaa atacggtaac ttgttcgata tgtacgaaga gatcacgaac
     3601 gataatccat acgagactcc gatgatgatc tacccggcat tgcactactc aatgggtgga
     3661 ttgtgggttg actatgagtt gatgacctcc attccgggtc tgttcgctat cggtgaggca
     3721 aacttctccg atcacggagc gaaccgttta ggtgcttccg ctttgatgca gggattggcc
     3781 gatggttatt tcgtattacc atacacgatc cagaactatt tgtccgacca aatccaagtt
     3841 cctcgcttca gcacggatct gccggagttc gtcgaggcag aaaaggccat caaggatcgt
     3901 atccaaaaat tgatgaacgt caagggtaaa gaaaccgtag acactatcca ccgcaaacta
     3961 ggtcatatca tgtgggaaca tatcggtatg gcacgcgacg caaaaggttt gcaagaagct
     4021 atccagatgc tgaaagactt gaagaaagag ttctggagca acgtattcat cccaggcaac
     4081 gcagacaact tgaataccga gttagagaaa gcattacgtg tagctgactt tatcgagatc
     4141 ggtacattga tggcacacga tgctttggac cgcgctgagt cttgtggtgg tcacttccgt
     4201 acggagcacc agacagaaga aggtgaggcc ttgcgtcatg acgataagtt catgtacgta
     4261 tcttgctggg agtaccaagg cgaggacaaa gatcctgtca tgttgaaaga ggatttgaac
     4321 tatgagttcg ttgttcctca aacacgtaac tacaagaagt aataatcatc aatctcagaa
     4381 aaaattagaa tcatggataa agatataagt gtaacactta aggtttggcg tcagagaggt
     4441 ccgaaggaga aaggacagtt cgagacatac aaaattgaga agatcaatca gagtgtctct
     4501 ttcttggaaa tgttggatat cttgaacgag cagttggtca acgagggtaa ggaaccgatc
     4561 gtattcgatc acgactgccg cgagggtatc tgtggcatgt gttcattgta tgtaaacgga
     4621 cacccgcacg gaccggcaac tggagctacg acttgccagt tatatatgcg tcgtttccac
     4681 gatggagaga cgatcacgat cgaaccgtgg cgttccgcag gtttccctgt tatccgcgac
     4741 ttgatggtag accgctacgc ttacgacaaa atcatccaag cgggtggttt cacatctgtc
     4801 aacacaggtg gtgtacccga cgctaatgcg atacctatcc caaagaagga cgcagactta
     4861 gccatggacg ctgccgcttg tatcggttgt ggcgcttgtg ctgccgcttg taagaatggt
     4921 tccgctatgt tattcgtatc cgctaaggtt agccagctgg ctttgttgcc tcaaggtaaa
     4981 gtcgaggctg ctcgccgtgc caaagctatg gtcgctaaaa tggatgagct tggcttcggt
     5041 aactgtacga acacacgtgc ttgcgagatg gaatgtccga agaatatctc cgttagcaac
     5101 atcgctcgtt tgaaccgcga gttcatttgc gctaaattac aagactaata tttgattagt
     5161 atatcatgga aaaggcgtct ttctctaaaa gaaaggcgcc tttttgtttt tgttatatgt
     5221 cgtaaaacat aatttagcat tataatcctt gacaggaatt gaaaagtccg tatatttgca
     5281 tcgtggtttt ttcataatag tattagattt aaggttaaca aagtttggtt agggcttgtc
     5341 gtgagacagg ctttaattgt ttatagacct accttttaaa catggaccat aaaatactgc
     5401 aaatagagat tgtttagcgt cattttatcg tcgatctttg cctttaaaga tcatatagta
     5461 tatgctaata agtattttat ttggcttctt atgttatttt ctccgggtgt tgatcaaaca
     5521 caaggaaaaa atcatgcgcc agataagaca aatggtaaaa caaaaataaa atggacaaaa
     5581 aacgaaccac cagttctttc agggcaatga gcacggaaag aaaactcgag tcgatcttcc
     5641 ttttcgtaac aggccgatgc aacgccaaat gcgcaatgtg tttctatgcc caagaaatgg
     5701 ataagaagca acccgacctc actttcgatg aaatcaagaa gatatcagaa accgccgggc
     5761 aattcaatcg attatggata tccgggggtg agcctacctt gcgtgaggat ctaccggaaa
     5821 tattggagtt attctacaaa aacaaccata tcaaagatgt gaacatccct acgaacggct
     5881 taaaaccaga ccggatcgtc gaatgggtaa aacggttccg ccagaactgc ccggattgta
     5941 atattaacgt aagcctttcc ttggatggtt tcggtacgac ccacgataca cagagaggcg
     6001 taccgggaaa cttctataag gccttggaaa ccctgcgtaa gatacaggag aatttcggag
     6061 atgacggcaa agtcttaaaa aatatagcaa ccgttatcac gaaatacaat atagaccaga
     6121 tagaagactt catgacttgg gtatacggac gtttccgtac ctccacgcat acgattgagg
     6181 ctgccagagg catgacccgt gacgatggcg tgaaaatcct aaccgagtca acgctacgca
     6241 aaatacaaga tgacatatcc cctatctatt ctgcttatgc ggatcggatg gtagcggata
     6301 ccaccggctt aaggaaaccg atcacacgct tcttctatct cggccttata cgtaccttat
     6361 ataatgtgcg tgccagcaac atagatcacc cgaccccttg ggggatggat tgtacggccg
     6421 gagagactac cttggtaatc gactacgacg gacgttttcg tgcctgcgag ctacgggaac
     6481 cgctcggaaa tataaaagag tatggttgcg atataagtaa agtgatgaat agcgaagcga
     6541 tgaaacagga aatagtcgct atcggacatg ggtataaagc caactgttgg tgtacgcacg
     6601 gctgttggat cacctcatcc atcattttca atccacgtaa gatgattcgc tccgtatata
     6661 aaggataccg ggaaacaaaa cgattgaatc atcccctagc catcaatgag cagaaactac
     6721 aaacgatgga agccaaatac catctggaca tcgagcgttt gcgtcaactg aatatccggt
     6781 aaacaagatc ctcatagccc ataaataaac gtagcatgaa aatactatta gtaaccagag
     6841 gctcacaagg cgacgtcctt ccttatttgg ccatagcggc cgaattggaa agacgtggcc
     6901 atgaggtgac catcaatctc cctcaaatat tcgaggagac cgttaaaccc tacggattta
     6961 aatacgtatt gcagcagttt gacgatatcg gcggcatgat cgatagcgca gcgcaaaact
     7021 cacataaatt ccggccattc cttaaatgga tgaggaacgt gatcgataaa cagttcgatc
     7081 aattgattcc cctactaaaa gagcatgata ttttagtatc gaccaactcg gaatttgctg
     7141 tcgcaagtat cgccgagtat tgcaagaagc ccttgatacg taccgcctac gccccgttct
     7201 tgccgggtaa gaagattccc ccggccgtat tgccatttcc caaacccaac ccgatcatca
     7261 cccctgccat cttatggaag ttgatgaacc ggatgaccaa tttcatggtc aaagacacga
     7321 tcaacaagaa ccgggctaaa tacggactcg caccgattcg taattttggt tatcatgcgg
     7381 gagagcgttc atataattac ttgcttttca gccagcacct aggaaacata gatccggact
     7441 ggacgttcaa atggtcgatc ggaggctatt gcttcaatga cacttttcaa tatgatgaga
     7501 aggcttacga ggaaatgata tcattcgtcg acagcgctca aagccctatt atctttttta
     7561 ccctcgggag ttgtagttcc aaggatggta accgttttag caaagccttg gtcgatattt
     7621 gcaagaaaca tgattatcgg ctcatcatcg attccggttg ggcaaagaca ggaatcacct
     7681 tacaagcgga taaacattta ttcttaatga agcagccggt tccgcataat ttgatatttc
     7741 cgcactgcga cggcgttatc catcatggag gttgcggcac gacccatagc gtaggaaggg
     7801 cgggaaagcc ccaattaatc actccgttga ttatcgatca accctattgg tcctatcgaa
     7861 tccaccaatt agggttaggg ccggaagggc ttaagatagc gaaagcgagc gagcaggaga
     7921 tcgaacgcaa ggtttgtgat ctggtcacca atccgcttta taagaaaaat gccgctcata
     7981 taggcgagat gatccaaaaa gagggaggta taaagaatat atgcgactct atcgaaagat
     8041 ttcaatgagg cataagttcc tattagattt tattacatgt tacaaaacac aatttagcac
     8101 ttaaactatt gacaaataat agtaactccg tatatttgca tcgtggtttt ttcataatag
     8161 tattagattt aaggttaaca aagtttggtt agggcttgtc gtgagacagg ctttaattgt
     8221 tttataaggt ctgcttcccg caaagccctt cgattacatc agaataatcc gatgcgtcaa
     8281 taaagttgat atcttgtctt ttaagatctt cccattaatc ggtttcgccg tataggcatc
     8341 aaatccacta ttaatgatcc gttgctcatc ttgggcgaaa gcataagccg tcaccgcgat
     8401 aataggcacg ctagcagaaa ccttacgaat ctctgcggta gcctcgtatc catccatgac
     8461 cggcatcttt atatccatca agatcaactg aggtttgtgc tgataaaata gctccacagc
     8521 ctcctttcca ttccatgcat gaatcaattt atattcaggc ttcaatatag actcaaacag
     8581 gcgataatta ctggaattgt cctcagcgat caagatcgta acctcacttc gggcgatctt
     8641 ctccaaagta acaggcttct gctcttcact aggaaataat tctttcttcg gctgaaaagg
     8701 caatgtaaac cagaacttag agcctttccc ttccatagaa tcaaccccga tcgttccttt
     8761 catctgggta acaatcatct cacagatgct taaacccaat cctgttcctt gagcgaaagt
     8821 gttcagtttc acaaaacgtc cgaaaatatc tttccgttta ttctccggga ttccgcagcc
     8881 cgtatcctct acatagaacc acaacgtatt atcatcccgc agtttatagc caaatgagat
     8941 caatcctgcc tgcgtaaatt tcatggcatt gttcaacaga ttgatcatca gttgggacag
     9001 acgatttcga tccgtataaa tcacgcaagg ctccagataa tccttaaatg agatctgtac
     9061 atccggattc ttattcttca aatgagccga ttgctccaaa tccctcaata cagcgttaat
     9121 atccacatag tcataagtaa actccaaggt acccgcctca atttttgaca aatccaagat
     9181 atcgtttatc aactgcaaca atagggaatt attattctcg ataatatcag cgaattcctt
     9241 cttatcctca aggttatcgg tcgaggcgag gatattagag aaacctacga tcgcattcaa
     9301 cggtgtacgt atctcatggc tcatattagc taaaaacgca gatttcaatt tattcgactc
     9361 ctccgcctta tccctagcca ttcgaaggtc atgttccaat tgcttacgct cggtaataga
     9421 tatcgtagac ccgatcaacg ctttcggttt accggaagca tcatattcga ccattacctg
     9481 tatctcctcc cactcatggc gatcttctcc cggaatcaac cgctccagac aatattcttt
     9541 tcgtactttc tttattttcc cattacacaa atcatcgaaa gccttttcca cgcaagccct
     9601 gaaagacggg tgtatcttgc tgaaatattc cttcaacgaa acctcatggg tatgcacctc
     9661 tgctgtctct atattatctc ccggatgtac tttcgactca tagataatct tctcttcagc
     9721 cagattatat cgccacggta aaagatctgc cgcctctaac gccatagcca gcttatgatt
     9781 catggctttc aaatgcgtct ggaatttatg gatatccgta atatcaataa aaaacgcatc
     9841 aaccacattc tcttccgagg taggcatgat gataatcgta tagtaaagcc ctgtcggctc
     9901 aaaataatac tcataagtga aggattttcc actctctaaa accgtaggca ctgccgatag
     9961 aagcaaagga taactcccgc caatcaaatt tgcgatctct tttccacgct tatttaccac
    10021 aaaatcttta ggagcgattt tctcctcgaa agcatggttc acatctaaaa cctgcacatc
    10081 gatttgcgta ccttctcgaa tcagtcgctg ccgtatataa ggtaacggca tattattaaa
    10141 taaatcacgg taacgggaca ataacctcaa ctctacttcc ttcatctttt gcttagaacg
    10201 atacacgtaa tgccacgcta aaaacacgac taccagaaag aatatcagaa agcctaacag
    10261 ttgcatccaa tatttttcca agaaagaggg aggcgcattc aagtagatcg catcacgcgg
    10321 gaaattatct tcattagata tcgcacttat caacgaagca taattcaaat atttatgagg
    10381 atcatttacc gtcgaaaccg ggatcttgcc catatcttca ccgttataaa cttgttgtag
    10441 caaggggatt agagcagtct caatcgtttt agcgctatta taatatccac caatcgtata
    10501 tccttcttcc acacccatat catataaaga aaaaacagga tgcctagaaa taccgtttat
    10561 accttgatat aaagtactat ataataacga gtgattcaag aaaggtttct cggtaatcca
    10621 cgagtaatac atcacggctg tcgctcgatg cggatctttc tccgacagaa ccgccaataa
    10681 actatccatg gagcaagaac cctccgtata aaaatccact ttcccctcag ggaaagaagt
    10741 ttccatatgt ttctccatct catcccggag ccatgtggaa acataacgtc tgtcggatat
    10801 gaaaatcaga cgtttcaaac ccgggattaa ttccttcacc aagtcgatcg aacctttaac
    10861 ataataaggg ataaccaatc ccgtagcgtt atacccctta accgcctctt gtaaaggaat
    10921 caccctatca gaggaatgcc tctgattaaa ataacattca ttttctgcca tttcccccgt
    10981 ctccgaacag accagagtgg gaatatcccc ccatttctcc cggatcttat cccgcataaa
    11041 agcccatcca tttacgccta agtagataat tccatccggc ttcttcttgt tagcttcaaa
    11101 gaagacctct tgtttctctt ttaatttctc tggcgtatca accaacatca cgcttatatg
    11161 atctatccgg agagtgtact cctccggggt agcgaacttc gagatcatgt ttaataaatt
    11221 accagaccaa cgttcgccat ccacatatga atttatcacc aatacatacg attcctcctt
    11281 gaccggatat gaagaactcc cataagccgg agtcggcata ccggctatca agcataaaat
    11341 caatcgaaaa taaagtatta ttgcctttaa atttataata tttcgtatca ttccctacat
    11401 tcctctattg cagttgtaaa gacaaagata ttccttaatt atcaactaat cttatcaaac
    11461 tagttttttt atcaagtttt ggtgtcaaat tcacgtttct tacaaactaa aggctttttt
    11521 aatcgggatt attcggttat ttaccgatac tcgtatagaa atcagcggta tttacttgtg
    11581 tatagaatga cgaacccgta catttgataa aaaacaaaaa aattgaactt atggatatga
    11641 aagattatga catcaatttt aaagagaaga ggacaaacgg gtatctgatc gctaccttat
    11701 ttatcattgt cggtatatta tttttactgc ggaatctagg aatgatagat ccatccttat
    11761 ttgacttgct tgtatcttgg ccgatgctgc ttgtcgtgtc gggcatcttt acgattttcc
    11821 accgtaatcc ggtaggaggt atgctcctcg tgggcgtggg agtctatttc cttttcccgc
    11881 agttaaattg gatcacgaac gattttttac gtgtatattg gccgttagga ttaatcctgt
    11941 taggattggt catcatgctg aagcggaaag attctatccg cacgaaaaag cataaacgtc
    12001 cctttaacca tccccctttc gggcacagaa agcctaacga tgagatcaac tacgagacag
    12061 ataacggttt cgtatcggtt gacaccactt tcaactcggt aaggcacatc gtactggacc
    12121 ccgtattcaa gggggcggac atagacgtat ctttcggcaa cgtgattctt gatcttaaaa
    12181 aaacaacatt agaggctgat gaaaccatca taaacataga tagctccttc agcggcgtag
    12241 taatatacgt tcctaaagga tggctggttc gtctaaaggt tggttctttc ttggctggat
    12301 gccaagatat gagggaactg acagaagcaa ccgacatgac gcatacacta tacatatgtg
    12361 gagacttgtc gttcagcggc cttgaactaa gagactaaac tcatcatgca agaacatcct
    12421 attacaacat ccatattaca taaagggctg ggaagcctat tactactttt agccatagcg
    12481 atccaatgcg cattattaac tctttatggc gatcttccgt tgagcatcac tttggtcgat
    12541 agcctacttt ccatcgcatt gttcgccgta gcgggatatt atctttggta tgtacaatgt
    12601 acgttacata tcatgcaagc acgagtggct ttcgccgtac tcgtacaaat cgcttgcata
    12661 gccggatgct cgatcttgct acaaatattc ggattggaag attgggagga attctcaatc
    12721 acgattcctt ttcgattcct gttcggccta atggcatgga tcattctatc ccaatggtat
    12781 gccagtcggg aaagaaagag tgaggcggaa cctatcgtga gacaaatgga ggaaaagacg
    12841 gcacctcccc cgactaccgt tccggaggag attctagatc gtatatccgt aaaagacggg
    12901 gcacgtattc atatcatccc gataaaagag atattctatt tgcaagcatg tggcgactat
    12961 gtgaccttat tcaccacttc cggtcagcac gtaaaggagc aaaccatgaa gtatttcgag
    13021 cgaagccttc cttctccgga gttcgttcgt atacaccgct cttatatcgt taatacggaa
    13081 cagatattgc gagtagaact attcggaaaa gaaacctatc aagtacgatt aaaggatgga
    13141 acctatcttc gtgccagtag cgctggctat aagctactca aagaacgtct ttccctttag
    13201 cagtcctatg aaagggatct aatcatcgtt aaaattagaa gattttgact gtaatatata
    13261 gagttttgtg ttgtgtaaca ctttttggca agcatcgata tgttacttaa catatattag
    13321 ttgcaaaaga cttgacaaat ggtcttgacg aacgtatctt tgcatcgtgg ttttttcata
    13381 atagtattag atttaaggtt aacaaagttt ggttagggct tgtcgtgaga caggctttaa
    13441 ttgtttatag ggatttgctt ccctagattt acatataact ataaaaaaac ggccacccct
    13501 aaaaagaggc ggccgtaatt ataccataag ataggatttc tattcctcaa caatacctac
    13561 gacttccatt tcaaaaatca tcgtagtgca aggttttaca acaacagccc cggtattagg
    13621 attcttatat cccgcttctc catatccaag ttgcgaggga acccaaatct cccatttatc
    13681 accgggatgc atattctgta aagccgtggc aaagccatca gtcatcttgt acacttccat
    13741 caccgcaggc tctccagcct cgaaagaacg atcatcaaaa acttcaccat ttataaaaga
    13801 gcctttataa taacattcca ccttgctcgt ataataaatc ggctccttac tctccccagt
    13861 cttcaagacc ttgtaaagga taaatccggc attactttga gaactcaatt gctcgaaacc
    13921 cggaaccagc atctgggctt gaaaagcctc ctcattctgg accttccaaa cctcatccac
    13981 ctctagtgcc tcatcatcat ccccacaaga ggtgatcatg agcacgcaaa acaacatcaa
    14041 cgcaatatgc cagtacttct tcattcgttt actctattac ctttttcaat aaattcttca
    14101 tgctcacctt ctccgtgata atatcgtgaa gcttatcgat gcttacgcgc tcttgctcca
    14161 tcgtgtcacg gaaacggatc gttacgcagt tatccttcaa ggtgtcatgg tctaccgtaa
    14221 tacaatacgg ggtaccgatc gcatcctgac ggcgataacg cttaccaata gaatccttct
    14281 cgtcgtattg gcaacggaag tcgaaacgca acatatttat aatctcctca gctttctcgg
    14341 gcaggccatc tttcttcacc aatggcaata cggccaattt gatcggagcc aaggctgcgg
    14401 gcaacttcaa taccacacgg ctctcgccat tcgccaacgt ctcctcgcag taagaacccg
    14461 ccatgatgct caagaacaca cggtctacac cgatcgaggt ctcgattaca tacggagtgt
    14521 aactctggtt caactccgga tcgaaatatt ggatcttttt accggaaaac ttctcatgct
    14581 gactcaagtc gaagttcgta cggctatgta taccctccac ttccttaaat ccgaatggca
    14641 tctcgaactc gatatccgta gccgcattag cgtagtgagc caatttctca tgatcgtgat
    14701 agcgatactt ctcatcgccc aaacctaggg cttgatgcca tttcaaacga gtagacttcc
    14761 atttcttaaa ccactcgatc tcctcacccg gacgaacgaa gaattgcatc tccatttgct
    14821 cgaactcgcg catacggaag ataaactgac gagccacgat ctcattacgg aacgccttac
    14881 cgatctgggc gataccgaac gggatcttca tacggccagt cttctgcaca ttcaagaagt
    14941 tcacgaaaat accttgagcc gtctccggac gaagataaat cttagtcgct ccatcagcgg
    15001 tagaacccat atccgtagag aacatcaagt taaactggcg aacctccgtc cagttacgag
    15061 ttccggaaat cgggcaaacg atctcgcaat ccaagatcaa ttggcgaaga tcctcgaagt
    15121 tagactcgtt catcgcctta ctataacg
//
