LOCUS       c00071_gnlPro..        16695 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NMEGLINO_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:26:12
            Original ID  :: gnl|Prokka|NMEGLINO_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16695
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16695
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8937:12408]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8938..12408
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16695
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16695
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(42..503)
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MKVIRAFCLCWLLMLADGVSAQLVDKVLSVLGEDSVGSVTVARTD
                     SDSIQLSLVRQELETARLNEANLRMEMEQMKLAGYAADSVKLALQKQRIDSLRTVTPGI
                     PVVVEKDTLFYLYAKRGGHTPQQRAKDVSNVIEALGTRFNLRPDSVYLT"
     CDS             618..1652
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="MKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIF
                     LSYTFAIAKRDGSMKEPEKEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVL
                     IYNL"
     CDS             1803..2939
                     /locus_tag="ctg71_3"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             3057..4991
                     /locus_tag="ctg71_4"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRTAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             4988..5446
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="CTP_transf_like (E-value: 6.3e-19,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             5469..7091
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(7165..7767)
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGIPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             7873..8775
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNCM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             8938..9636
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_9"
                     /sec_met_domain="SucD_FumR (E-value: 1e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             9673..11619
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.7; E-value:
                     2.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_10"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.8e-62, bitscore:
                     199.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAIQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             11653..12408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_11"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4.1e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(12547..13494)
                     /locus_tag="ctg71_12"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHPRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(13559..14527)
                     /locus_tag="ctg71_13"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATAMASVATFDAMKEFMTDVKVTYSAPNWSLTGGTYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAAGAIYPSITYTVADVAAQTDLVAAKVTDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSTWKSQEGTATYA
                     HTIAGSALEVNTTGVEMNAAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSTIDLDGT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             complement(14573..15577)
                     /locus_tag="ctg71_14"
                     /transl_table=11
                     /translation="VASNVGEMSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSG
                     VQIKLDWKGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNT
                     ESIQIRGDESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLDWK
                     PEAVVDHYSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLL
                     WGYFSSFVLLKDAKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPN
                     VGVPGSEIHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(15553..16176)
                     /locus_tag="ctg71_15"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKVSLVWLLTSGR"
ORIGIN
        1 acattagata cacaacttac actgttttga attcgtcgaa ctcacgttaa ataaacagag
       61 tccggacgca gattgaaacg cgtacccaat gcttcgatga cgttgcttac atctttggct
      121 cgctgttggg gcgtatgccc tccacgcttg gcatacagat agaacaaagt gtccttctcc
      181 accaccaccg gaatacccgg tgtcaccgtc cgcaacgaat caatgcgttg tttctgcaat
      241 gccagcttca ccgaatcggc cgcatagccc gccaacttca tctgctccat ttccatccgc
      301 aggttcgcct cattcagccg ggctgtttcc aactcctgcc ggacaagcga caactgaatc
      361 gaatcggagt cagtccttgc cactgtgaca ctccccacac tatcctcacc taaaacactg
      421 agcactttat ctaccaactg agctgacact ccgtctgcca gcatcaacag ccaacaaaga
      481 cagaaagcac ggataacctt catatataaa cttcttgatt tgattcttta attatgcaaa
      541 tatacccaat aaatgcttca aacatacgga atgtttttaa cttcctatcc taatcaacat
      601 aactttttca tgcaaacatg aaagttctgt atccggtttg cattatcttt gtactcaaaa
      661 ttgacatacc tatggatata ttgtttcttg tcggaggact gctcctcatt cttctgggtg
      721 ccaatggctt gacagacggt gccgcatccg ttgccaaacg tttccacata ccgtccatcg
      781 tcatcgggct caccattgtt gccttcggca cttccgcacc ggaactcacc gtcagcatat
      841 cctctgccct aaaaggcagt gcagacattg ccatcggcaa tgtggtggga agcaatacgt
      901 tcaataccct gatgattgtg ggttgtacgg ccctttttgc cccgatagcc attacccgta
      961 acacactgaa acgcgaaata cccctttgca tcctttcatc cttcgccctg ctgatttgtg
     1021 ccaacgacgt cttactggac agcagtgggg agaacatact cagcatcacc gacggcctat
     1081 tgctgctatg cttctttacc attttcctga gttatacttt tgccattgca aaaagggatg
     1141 gaagtatgaa ggaaccggaa aaggagcact tacaggaaga agacgaaatc aggctgttac
     1201 ccgcgtggaa gtccgcccta tacattctcg gcggacttgc cggcctcatc atcggaggta
     1261 atttctttgt agacggtgcc agcggcatag cccgcggatt gggtgtcagc gaatccatca
     1321 tcggtctcac gctcgtagca ggcggcactt cattacccga actcgccacc tccatcgtag
     1381 ccgccttgaa gaaaaacccc gaaatagcca tcggaaacgt catcggaagt aatctcttca
     1441 atatattctt cgtactgggt tgttcggcct ccatcactcc actgcgtctg acgggcatca
     1501 ccaatttcga tttgtgggta ctcgtagggt ccagcatcct gctttggctg ttcggtatct
     1561 ttttcgggaa acgcatcatc acccgggtgg aaggaagcat tctgattctc tgctacattg
     1621 cctacacagc ggtactgata tacaacctct aacagcaaat ttacaaacac cctacgcggt
     1681 attttaaaga ttatcacgta tttttaaata aggcaagctg tacctcggca taaaaaataa
     1741 gcaagcttat tttgttctgc tctcagtttg cattaccttt gtggtctcaa tattgaacaa
     1801 ctatggcaat tacaatcaag aaagtaacca caagacggga actggagcgc tttatccgtt
     1861 tcaactacct gctatacaaa aacaaccctt attccgtccc cgaccttttc gatgacatgc
     1921 tcaacacctt caacaagaag aaaaacgctg cattcgaatt ttgtgaagcc gactatttcc
     1981 tggcttatcg ggaaggtaaa atcgtaggac gtgtagctgc catcatcaac cacaaggcaa
     2041 accaaacctg gaacaaaaag gaagtccgct tcggctggat agacttcatc gatgatgcgg
     2101 aagtctccga tgccctgatt cgcaccgtgg aagaatgggg aaaagaacgg ggaatgacac
     2161 atatacaagg cccgctggga ttcacagatt tcgatgccga aggtatgctc atcgaaggat
     2221 tcgaccagct cagcaccatg gccaccattt ataactatcc ctactatccg caacatctgg
     2281 aacgcatggg ctttgagaag gatgccgatt gggtggaata caaaatctac attcccgacg
     2341 ccatacccga caagcacaag cgcatctccg acctcatcca gcgcaagtat aacctcaagg
     2401 taaagaaata cacatctgcc aagaagattg cccaagacta cggtcaggcc atcttcgaac
     2461 tgatgaacga agcctatcag ccactctatg gctattctgc actgagccaa cggcagattg
     2521 accaatacgt caagatgtac ctgcccatcc tcgacctacg catggtgaca ttgattaccg
     2581 atgccgatga ccagctgctt gccgtaggca tttccatgcc gtcactcgcc gaagcgttgc
     2641 aaaaagccca cgggcgcctg cttcctatgg gttggtatca cctggccaag accatcttct
     2701 tgaagaaata tcccaagatg ctcgatttgc tgctggttgc cgtgaaaccg gagtatcaga
     2761 acaagggggt aaatgcattg ttgttctccg accttatccc cgtctatcag caacttggtt
     2821 tcgagtatgc cgagagtaat ccggagctgg agctgaacgg caaggtgcaa gcgcagtggg
     2881 agtacttcaa gacggaacag cataaacgga gaagatgctt tgtgaaagga ataaaataag
     2941 ttctaaatcc agaatataag cttgtcagaa gtccataaaa gacattattt ttttgcgaac
     3001 ccccgaattt ctcattacct ttgtcgcaat gcgcaatatg aaggaataac gtacttatgg
     3061 aagataacaa caatatgacc ctgccgctgg aagaagcaga caacaatatc acagagagcc
     3121 ccgtttccag cgtggaatat accgacgaca acatccgcca cctggacgac atggagcata
     3181 tccgtgtccg ttccggtatg tacataggcc gtctgggcga cggctcacag aacgatgacg
     3241 gcatctatgt gttgctgaaa gaagtgatgg acaacagcat cgacgagttc aagatgggtg
     3301 ccggaaagcg tatagaagtg actatagaag acagtctgcg tgtcagcgta cgcgactatg
     3361 gacgaggcat tccgcaaggc aaactggtag aggcggtcag caaactgaat accgggggta
     3421 aatatgactc gaaggctttc aagaaaagtg tcggactgaa cggcgtgggc atcaaggcgg
     3481 tcaatgcgct gagtagccgt ttcgaggtac gcagttaccg cgacggcaaa gtacgtaccg
     3541 ccatcttcga gaaaggaacg ctgttgagtg atgtgaccga agactcgaca gaagaaagcg
     3601 gaacctatat cttcttcgaa ccggacgcca cactcttcct gaactattcc ttccagaacc
     3661 agttcgtaga aaccctgctg cgcaactaca cctacctgaa tacgggcctc accttcattt
     3721 acaacggcca gcgcatcgtt tcccgccacg ggctggagga cttgctgaaa gacaacatga
     3781 ccagcgaagg cctttacgac atcatccacc tgaaaggaga ggacatcgag attgccttca
     3841 cacacaccaa ccaatacggc gaagagtact actcctttgt caacgggcaa cacaccaccc
     3901 aaggcggcac acaccagact gccttgaagg aacacattgc ccgtaccatc aaggagttct
     3961 acaacaagaa ccaggaatat gccgacatcc gcaacggact ggtagccgcc attgccatcg
     4021 acgtggagga acccatgttc gagagccaga ccaaaacgaa actgggcagc aacaacatgt
     4081 ggcctgccgc gccgcaggaa cacaagcccg ccggccccac ggtgaacaaa tacgtaggag
     4141 acttcatcaa gacggaagtg gacaactacc tccacaagaa cccgcttgtg gccgaagtga
     4201 tgctgcaaaa gatacaagac tccgagaaag agcgcaaagc cattgccggc gtcaccaagc
     4261 tggcacgcga acgcgccaag aaagccaacc tgcacaaccg caagctgcgc gactgccgct
     4321 accacttgag tgacggtaaa ggcaaagacc aggaaaccga atcctgcatc ttcattaccg
     4381 agggagactc tgccagcggt tccatcacca agagccgcga cgtgaatacc caagcagtat
     4441 tcagcctgcg tggtaaaccg ctaaattcct acggactcac caagaaagta gtttatgaaa
     4501 acgaagaatt caacttgctt caagcagcct tgaatataga agacggcata gagacactgc
     4561 gctacaacaa agtcatcgta gctaccgatg ccgatgtgga cggcatgcac atccgcctgc
     4621 tcatcatcac cttcttcctg caattcttcc ccgacctgat aaagaaaggg catgtatata
     4681 tcctgcaaac ccctctcttc cgcgtgcgca acaaaaagaa gacaagttat tgctatacag
     4741 aggaggaacg tgtgaaagcc attgaagaac tgggtcccaa ccccgaaatc acccgattca
     4801 aaggtctggg agaaatctcg cccgacgagt tcaagcattt tatcggcaag gatatgcgtc
     4861 tggaacaagt gtccctgcgc aagacagacc tcgtaaaaga gctgctggaa ttctacatgg
     4921 gtaagaatac catggaacga caaaacttta ttatcaacaa cttggttata gaagaagatt
     4981 tggcatcatg agaagagcta tctttccggg aacattcgac ccgtttacta tcggacactc
     5041 ttcggtagtg agccgtgcac tgacttttat agacgaaatc gtcataggca tcggcatcaa
     5101 tgaaaataag aatacgtatt tccccttgga aaagcgcgaa caaatgatac gagactacta
     5161 ccggaacgag ccgcgcatca ttgtgcagtc ctatgactgc ctgactatcg actttgcccg
     5221 gcaggtagat gccagtctga taatacgcgg catacgcacc gtgaaggatt tcgaatacga
     5281 ggaaaccatt gccgacatca accgcaaact gaccggcata gaaaccatcc tgctcttcac
     5341 cgagccagaa cttacctgcg tcagttccac caccgtgcgc gaactgctgc aatacggcaa
     5401 ggacataagc atgttcatac cggagggaat ggagattagg gattaaggat aaaggattag
     5461 ggattaaaat ggaaatgatg aaaaaactat ttactattat aatatgtata tgcgcggtga
     5521 cggcacaagc gcaaaagccg aacaatgaag ccctgcgcaa actgcaaatg gcagagtttg
     5581 ccatcaccaa cctttatgtg gacaaggtgg atgaagacaa actggtggaa gaagccatca
     5641 tcaagatgct ggcacaactc gacccgcact ccacctacaa caacgccgaa gaagtgaaga
     5701 agatgaacga gccgttgcaa ggcaatttcg agggcatcgg cgtacagttt cagatgatag
     5761 aagataccct gcttgtgata caacccgtga gcaacggacc ttccgagaag gtgggcatcc
     5821 ttgccggcga ccgtatcgta gccgtcaatg acagcgccat tgccggagta aaaatgagca
     5881 cggaagatat tatgagccgc ctgcgcggac cgaaagactc ggaagtgaaa ctcaccatcg
     5941 tgcgccgtgg cgtggacgac cagctgtact tcaccgtgaa gcgtgacaaa attcccatcc
     6001 tcagcctgga cgcatcttac atgatacaac ccaaaaccgg ctatatccgt atcaaccgct
     6061 tcggggcaac caccgccgaa gagtttgcag aagccctgaa aagcctgcaa aagaaaggaa
     6121 tgaaagacct catcctcgac ctgcaaggaa atggaggagg gtatctgaat gccgccatcg
     6181 accttgccaa cgaatttctg aagcaaaaag aactcatcgt ctacaccgaa ggaagggccg
     6241 cacgccgcag tgatttcttt gccaaaggta cgggcaactt caagaacggc cgtctcatca
     6301 tattggtgga cgagtactcc gcttctgcca gtgaaatcgt gaccggagcc atccaggact
     6361 gggacagagg cgtggtagta ggacgccgca ccttcggcaa gggattagta cagcgtccta
     6421 tcgacctgcc ggacggttcc atgattcgcc tcactatcgc ccgctactat actccttcgg
     6481 gccgttgtat ccagaagcct tacgacagca ccgccaacct cgacggccgc ctaaccggcg
     6541 agaacagtca ggataagtat aaccaggaac tgatagaccg cttcaatcat ggagaaatga
     6601 ttcatgcgga cagtatccat tttgccgact ccctgaaagc acagaccaag cgtatgggac
     6661 gtaccgttta cggaggtgga ggtatcatgc ccgacttctt cgtccccatc gacactaccc
     6721 agtacacaga ctatcaccgc aacctcgtag ccaaaggcgt ggttatcaaa gccactaccg
     6781 gctacatcga gaagcaccgg aaggagttgc agaacaaata caagaaattc gaagccttca
     6841 acgagaagtt cgagatagac gataacttcc ttgccgaaat acgtacgctt gccgacaaag
     6901 agaaaatcaa gtttgacgag aaacagtaca accaatccct accgctcatc aagacacaac
     6961 ttaaagcctt gatagcccgt gacctatggg acatgaacga atacttccag gtgatgaaca
     7021 gcacgaacca gagcgtgcag caagctctaa aagtgttgaa cgaaggcatc tacagcacta
     7081 ttatccaata gccgacttga aacaaactta ggcgcggatt atgcggattt agtttatcta
     7141 attccgcgta attcgcgcct aaaatcattc tccgaacagc cacttattca gccacttgtt
     7201 gacgtagatg ttgaccacag cacatccagc accgattgca gcccccgcca acacatccga
     7261 cggataatgc actccctcgt tcatacggga aactcccacg gaacaagccc acagggcaga
     7321 cggagctatc acataccatt taggatactt tacactgagc gaggtggcaa gggcaaaagc
     7381 cgtcgccgta tgtccggaag gaaaagacgg gctgccttca tggctatatg catgcactct
     7441 gtcgggatat ttatcataag gacgctcacg gtccaccaga tatttcattc cataagtcac
     7501 aacaaaagcc cccgctacac ttgtacctac gtagaccgca tctttcagca aacccttatc
     7561 atgttttatc caagcggcaa ccgccatcgc caccggaata ccgacagcaa catagggctc
     7621 cgaacgtgaa attatcttat tatagttacg gacaaacttg ccatcccaac tgttaacccg
     7681 gtgcaaagtg ttaatatccc aattctgtgc cgaaagaccg gatacaacaa ggcagataaa
     7741 atatacaaaa aaaatagcct ttttcataag tcctttatat tagtttgacg caaagatagg
     7801 acaaatagat agagttttca caaaaaaatt ctatctttgt tgccacattt ataataattc
     7861 gctaatcatt tcatgagact ggaaacttgc tgcaaccgac agattgattg tatggtatgt
     7921 ccccaaaaat cagaaggagt attggtttac cgccactacc ccaagggaca acatttctct
     7981 gctgaaaagt gcacacagaa ctgcatgata tttatgctga aaggtgaatt acttgtaaac
     8041 agtgacgaat atccgggcac cactctccaa agccgccagc tcatcttgca agccatcggc
     8101 tccaaagtag aactcctggc tttgaccgaa gtggaatata ttgtctattg gttcaccgag
     8161 cttcctctga tttgcgaaga gcgctacaag gagatactga aacgctcgga agcccccttg
     8221 acttataccc cgcttaccgc gatttccatg ctcgaagggc tcctgaaaag ccttgcctgc
     8281 tacctcaacg agcaacccta tgcgtgcagc aaatacattg aaatgaaatg ccaggaattg
     8341 gtatacatat tgacatgcta ctatccgcta caccaaatca gtacattctt ctaccccatc
     8401 agcacttata cggaaagctt ccaatatttc gtcatgcaga actacgacaa ggtgaagaat
     8461 gtggaagagt ttgcccacct cggtggatat accaccacca cattccgccg tctgtttaaa
     8521 aatatgtatg gggtcccggt ctatgaatgg attctggaca agaaacgtga aggaattctg
     8581 aacgacctgc aatacaccaa acaacgcatt tcagtcatca gcgcccgcta tggctttgat
     8641 tccctatccc actttgccca cttctgcaaa gactctttcg gagacacgcc ccgcgccctg
     8701 agaaaacgtt cagcaaacgg agaaaagatt tccattatct gcaaagagca aggcaaagac
     8761 caggaggacg agtaaacctt ttacttgtcc gtaaacttcg cattctgccg gattacggaa
     8821 ttatttcttt aatcgcttgc tttatcgctg gatttctcct atttttgcga aacatttaca
     8881 gaagtatcct gatagaacaa attttcaaac tattaaataa cttaaattca atcatttatg
     8941 tggttaagta attcatctgt aggaaggaaa gtggtgatga gcgttaccgg tatcgccctt
     9001 gtcctgtttc tgacatttca catggcgatg aacctggttg cattagtctc ggctaatggc
     9061 tacaacatgg tttgtgagtt cctgggagca aactggtacg cattggtggc tacggtaggt
     9121 ctggctgcct tattcatcat ccacatcatc tacgctttct ggctgactat gcagaaccgt
     9181 aaggcacgtg gtagcgaacg ctatgccgtt acggaaaagc ccaagactgt ggaatgggct
     9241 tctcaaaaca tgctcgtact gggtatcatc gtaatcgtgg gtttgggcct gcacctggta
     9301 aacttctggg ctaaaatgca gcttcccgag ttgatgcaca acatgggcat gcatgctgac
     9361 accctcacgc tggcatatgc agccaacggt gtctatcaca ttcaaaacac cttcagcaat
     9421 ccggtattcg tagtgcttta cctcgtttgg ctgggcgcat tgtggttcca cctcactcac
     9481 ggtttctgga gctccatgca gtctttgggc tggaacaaca aagtatggat taaccgttgg
     9541 aaatgtatct ccaacatcta ttctactatc gttgtcctct gcttcgctct ggtagttgtc
     9601 gtattctttg caaaatcatt gtgcggcgct tgctaaattc aaattgtaaa tgactaaatt
     9661 gtaaattgca ttatgactaa gatagattct aaaataccgg aaggaccggt ggctgagaaa
     9721 tggaccaatt ataaggctca ccaaaaatta gtaaaccctg ccaacaaacg tcgtctggac
     9781 atcatcgtag taggaaccgg acttgccggt gccagtgctg ccgcctctct gggcgaaatg
     9841 ggtttcagag tattcaactt ctgcatccag gactctccgc gccgtgcaca ctccatcgct
     9901 gcacaaggtg gtatcaatgc tgctaagaat taccaaaacg acggtgactc tgtataccgt
     9961 ctgttctacg atacagtaaa gggtggcgac taccgtgccc gcgaagctaa cgtttaccgt
    10021 ctggctgaag tatccaacaa tattatcgac caatgcgttg cacaaggtgt tcctttcgcc
    10081 cgcgaatacg gcggtacact ggacaaccgt tctttcggtg gtgctcaggt atcccgtact
    10141 ttctatgcca agggtcagac cggacagcag ctgttgctgg gtgcatactc tgcattgagc
    10201 cgccaggtga acgtaggcac tgtgaaactg tatacccgct acgaaatgga agacgttgtc
    10261 ctcattgacg gacgtgcccg cggtatcatt gcaaagaacc tcgttaccgg taaattggaa
    10321 cgttttgccg cccacgctgt ggtaatcgct accggtggtt acggcaatgc ctacttcctt
    10381 tctaccaatg caatggcatg taactgctct gcagcaatgg cttgctatcg taaaggtgcc
    10441 tggtttgcta accctgctta cgtacagatt caccccactt gtatcccggt tcacggtgac
    10501 aagcagtcta agctgacttt gatgtccgaa tctctgcgta acgatggtcg tatctgggtt
    10561 ccgaagaagc tggaagatgc caagaaactg caggaaggta cactgcaagg aaaagatatt
    10621 cccgaggaag accgcgacta ctacctggaa cgccgttatc cggcattcgg taacctcgtt
    10681 ccgcgtgacg ttgccagccg cgctgccaaa gaacgctgcg acaagggctt cggcgtaaac
    10741 aacaccggtc ttgccgtatt ccttgacttc tccgaagcta tcaaccgtct gggtaaagat
    10801 gtcgttgcac aacgttacgg caacctcttc gatatgtatg aagaaatcac tgatgtcagc
    10861 ccatacgaaa acccgatgat gatttatccg gctatccact ataccatggg tggtatctgg
    10921 gttgactacg aactgatgac ctccatcaag ggactgttcg ccatcggtga atgtaacttc
    10981 tccgaccacg gtgcaaaccg cctcggtgct tccgccctga tgcaaggtct ggccgatggt
    11041 tacttcgtat tgccttacac tatccagaac tatctggccg accagattac agttccccgt
    11101 ttctctaccg acctgcccga atttgcagct gcagaaaagg ccattcagga gaagattgac
    11161 tggatgatga acatcaaggg taagaagtct gtagactcta tccacaagga actgggccac
    11221 attatgtggg aatatgtagg tatgggacgt acggccgaag gcttgaagga aggtctgaag
    11281 aagctgaaag aagtccgcaa ggagttcgag aaagaactgt tcatcccagg cgacaaggaa
    11341 ggtatgaatg tagaactcga caaggctatc cgtctgtacg acttcatcac tatgggcgag
    11401 ctggttgctt acgatgcact gaaccgtaac gaaagctgcg gcggtcactt ccgtgaagaa
    11461 tatcagactg aagaaggcga agccaagcgt gacgatgaaa actacttcta cgtggcttgc
    11521 tgggaatatc agggttctga cgaaaaggaa ccggtattgc tgaaagagcc gctggtttac
    11581 gaagcaatca aggtacagac tcgtaactac aagagctaat cgggaagttg aacatttaaa
    11641 gaattaaaga aaatggataa aaatatatca tttacgctca aggtatggcg ccagaagggt
    11701 ccgaaagcaa aaggcgcttt tgaaacatac caaatgaaag atatcccggg cgatacttca
    11761 ttcctcgaaa tgctggatat cttgaacgaa cagctgattt ctgaaggtaa agaaccggtt
    11821 gtattcgacc acgactgccg cgaaggtatc tgcggtatgt gttcgctcta catcaacgga
    11881 cacccccacg gtcctgcaac cggcgctacg acttgccaga tttatatgcg tcgtttcaac
    11941 gacggcgata ccatcactgt tgaaccgtgg cgctctgccg gttttccggt tatcaaggac
    12001 ttgatggtcg accgtacggc ctacgacaag attatgcagg caggcggcta cgtcagcgta
    12061 cgtaccggtg ctccccagga tgccaacgct atcctgattc cgaagcccat cgctgacgag
    12121 gctatggatg ctgccagctg tatcggttgt ggtgcttgtg tggctgcttg taagaacggt
    12181 tctgctatgc tgttcgtttc tgccaaggtg agccagctga acctgttgcc ccaaggcaaa
    12241 ccggaagcat tgcgccgtgc caaggctatg ttgagcaaga tggacgaact cggtttcggt
    12301 aactgtacaa acactcgtgc gtgcgaagct gaatgcccga agaatgtttc catcagcaac
    12361 attgctcgcc tgaaccgcga ctttatcatt gcgaaactga aagactaatc cggtctttct
    12421 gcaaataata taggatgcgc ttcggataaa ccttttgagc aagctcagat ttatcactca
    12481 gctttcacta tatttgatta atatcacaag agactcctct gccgggaaac cgccggagga
    12541 gtttttttat gacatgccgt ttacttcaga taaattgccg gcacgcaagc tacggggaga
    12601 agccccgaaa ttctttttgc agaaattgga aaaatgaggc agcgattcaa agccatattt
    12661 atagcaaatc tctgatatag aagcatccgt ataacgaagt tcataaacca cgctttcctt
    12721 cctccgttcc atcatccact cgtacaccgg ttgatgaaaa acagaattga atatacgccg
    12781 gaaagtagct actgtatatc ctcccaactg ggcaagttcc tctaccgtct tgactttggc
    12841 atgattctgc aagacaaagt agtggaagga attagtatac tgggcaagag gatgtatcag
    12901 catggaaagc tcatagtcgg agtagtaatt tccaagaatg aaagcaagtt ctttccgttt
    12961 gaaacaaagc atttcccggc aaatcttctc ctcggacaaa taggccttgg aactttccag
    13021 aaagagctgc aactcgggag taatggtcaa aggatagaat atcaatggag gggtaacctc
    13081 tttcataata tggttatacc ggtcctcaca gaagaattca ggcttactga accggtaaca
    13141 aacgcattcc acatccgtca tggcaagtat ttcgtacttg gaaccaatag cttgaaggat
    13201 gaactcacct gcatgcaaca cagttcccgc atactcctta ctgttgacaa gcacttctcc
    13261 tttcagcagg aaaattataa tattttcctc acactttcgc gccggcagat ggaatcctct
    13321 ggggtgggaa gcatatatta ttgcattgtc cacagccttg ggacattgag cgcattgttt
    13381 tttacctctg caagcagaag agttgggcat cggcaagtag atttgtttgt ttgttgcagt
    13441 gacaaaaata gataaataat actcataaaa gaaacattcc ccgaaaactt tcataaagaa
    13501 gtttcgggga atgaataaaa tagaagtaat tcagtttttt attgcggaca gtgccgtttt
    13561 atttttccac gttcgtatca tcagccgtac tccatggacc aacttcaggt acaaaggtta
    13621 cttttgccgc cttattggcc agcgtcagcg tataacgtat ctttttgcct tcaccccagg
    13681 cttgtgtacc atccaagtca atggtggaag ttacagtatc aagaagaacg tctttctcat
    13741 agatgtcata gacaacattg attttggcat tcgtatccaa cgtctggggc atcaacatcc
    13801 aggctgcatt catttccaca cccgttgtat tcacttccaa tgcactgccg gcaatcgtat
    13861 gcgcataagt ggctgttcct tcttgtgact tccatgttga atcatcaaaa ccataagttc
    13921 ccttattgtg cacgccggat attgtaagtg ttttcagttt ataagtcaaa gcgtcggctg
    13981 ccttgacagt gaaatttatt tgggtcagta tatggccgaa tttcaaagat accccactgg
    14041 catttgatgc cttggttgca tccgtcactt tcgcggctac caagtccgtt tgggcagcta
    14101 catctgctac cgtataagta atggaaggat atatagcacc agcagccggt tgattgtacg
    14161 tcaaggctcc ggtacccgga ttcccgtaag caaagaactg caagttatcc gtcattggcc
    14221 aataatatgt tcccccagtc aaactccagt tgggagcact ataggttact ttaacatctg
    14281 tcatgaattc cttcatcgca tcaaaagtcg caacggaggc cattgctgtc gctcccgtat
    14341 tataagcata cacagtgaac cctaccttct gcaattccgg caaatcagtc actgtggctc
    14401 tcgtagtgtt acccactact gttcccaatt taatctctgc cttttgtccg gcattctcta
    14461 tctcctcact ttccgagcaa ctcattactg ctgctgcagc caaagccaaa aataaaacct
    14521 tcttcataat tgtctgttat taaagttaat atatttattt gtctgtttgc tatcaattca
    14581 ccggtagctc cacatccgtc tcatcatccc aatcatccac atcgccacca atccctccat
    14641 ctccttcatc ggttcccggt tccaaatcat ccaccacaac cttgtcctcc ggtacgggaa
    14701 cctcgatatg gatttccgac ccaggaacgc ccacattagg ttcttcttcg cctcctcccg
    14761 agggaggagc tgtttcaatc acttccgtga tgtctacctt cacctcttga accgttttat
    14821 ctcgtttcac aatcttcagt gtcagcaaca taggactatc cgcacgggtc ttggcatctt
    14881 tcaataatac aaaactggag aaataccccc ataaaagccc gttttcacgt tttgtatcca
    14941 cacatatagg tacctcgctc aaatggcaag cacggttgcc tataaagtaa cttccgttca
    15001 agccgtccac atggcagatg atgctcgata ttctatccca tccttccacc tttatatcaa
    15061 aggaataatg gtccactacc gcttccggct tccagtccaa cggaagcgcc acatcactct
    15121 gccttatttc cacctcgtcc aaagccacca catacaaagg gtcgggcgac caaaccatat
    15181 cttcgtgtac atccagcccc gtacagtgtc ccgtaaaagc ctcaatcgtc tcataactct
    15241 cgtcgccccg tatctgtata ctctccgtat tgaagttata ggccaccacc gcatacttcc
    15301 ccggcggtac cttcacctca ccccctccgg caggcagata actttcaacc tttctcccct
    15361 gagtatcttt cggatagaag ataatccgca tggtctgcgg cagcttatcc gtcacccctt
    15421 tccaatccag tttaatctgt actccgctaa cgggataatc atccagcata tcgcggaagt
    15481 cacagcttcc cagcattggc aacagcccga agaacagcca gagaatcata tgccgtgcat
    15541 ctttcatacc actcatctcc ccgacgttag aagccacacc aaagaaactt ttgcttttgt
    15601 cggcccgata aagtgatact ttccactgct gacccaaacc aagtcatttc cataagaagt
    15661 atatttcctg tactccgtat ccaagtatcc aatgcccaca ctgaattcaa tcgccagatg
    15721 ccgagccagt ggacgcacgt atccataagt tattcctgca gctgcgtaat acttcccccg
    15781 gtatcccttc tcctttttca actgaaaatc ataggtacct ccttcggcat atgctcccag
    15841 gaagtgtccg gacaatcttc cgcgcgtatg gcggtttccc aaccagtaac gcgcctctgt
    15901 ccctcccgaa aggagctgat agcagaaatt acatccgctg tcagaccacc aagggcattt
    15961 gtactcaaca ttcaaagacc acctctttcc caatggcagc tccacttcta tgttcggagc
    16021 caaggccagg tcgtaaagca aattattttt taacgccagc accgttttac aagtatggct
    16081 atgggattct accgacttat tctgccctat tacctgcccc gacatcatgc aaaaaaggag
    16141 tagccaaaag acatatataa aaatgcgttt tcccataatt tcgcgttgta tacaaacaaa
    16201 agtagaagat aattaccgaa taaaaatcac tttccatcac tcttttcaaa ggctgaaagg
    16261 ttctgtgaaa cgattgaaac agatttgcaa cttctgcctt atccgggacg ctgtgaatag
    16321 attcttctct ctcaaaaagt caatccgtgt gcgaaaacag taaaattcag tgaaagaaat
    16381 acaaaagaag tagcaggaac attctgaaat ttggaagata acaacgggaa ccttacattt
    16441 gtaatgtgat ttttttcata gtattagatt taaggttaac aaaggttgga gtacagcggt
    16501 actccttttt ttatgcccat acgtttctcc gaatgacaaa aaatagctat ctttgatggc
    16561 ttttataact gttaaagaag aaaacatcac cacttgagcc cattatgaaa aaaccggtac
    16621 tcgcattgct ttccataatc ctaacgtgag ttcgacgaat tataactatc tataaatttg
    16681 gtgattagcg aaaat
//
