LOCUS       c00008_gnlPro..        13325 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNHALEOO_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:22:06
            Original ID  :: gnl|Prokka|CNHALEOO_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13325
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13325
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[366:3325]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      367..3325
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13325
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13325
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..154)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCLSATN
                     AENQQI"
     CDS             367..2595
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="Gly_radical (E-value: 2.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2600..3325
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.8e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3557..4819)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4871..5419)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTVLQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5607..6359
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6464..7462)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.9e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7532..8005
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8109..9107)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.8e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9162..10430)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_10"
                     /sec_met_domain="MFS_1 (E-value: 5e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10680..11693)
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDCSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11716..12852)
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 caatctgctg attttcagcg tttgttgcgg agagacaggg attcgaaccc cgggtacctc
       61 gcagtacaac ggttttcaag accgccgcaa tcgaccactc tgccacctct ccagaactac
      121 ggttaagtag tgcttttctc ttaaagcgct gcaaaggtac gaatcatttt ttaacttgca
      181 aattattccg caaaaaaata ttagaaaagt atatttggaa gtaataactg ctatctggct
      241 tctccccata aataggtatt tttatgctat tcaacataaa ataggaccct tttatatacc
      301 taaaccgaaa aaaggttgta aatttgcgcg ctctaaagga taactaacca ctaactgatt
      361 aattttatgg aactgaataa gacctttaaa gatggacttt ggagcaaaga aatcaatgta
      421 agggatttcg ttagtaacaa catcactcct tatgaagggg atgcttcttt cctgcaagga
      481 cctaccgaac gcaccaaagc tgtctggaat cactgtctca aagctctcga agaagagaga
      541 aacaataatg gtattcgtgc actcgactac acaactgtat ctactataac ctctcaccct
      601 gccggctaca tcgataaaga aaacgaactg atcgtcggac tacagaccga tcaggtgtta
      661 aaacgtgcca tcaaaccgtt tggcggaatc aatgtggtta tgaaagcttg ccgtgaaaac
      721 ggagtggaag tagatgacag agttaaggat atcttcactc actatcgcaa gactcacaat
      781 gatggggtat tcgatgtgta taccgaagaa attcgttcgt tccgttcctt gggattcctt
      841 accggacttc ccgacaacta tgcacgcgga cgtatcatcg gtgattatcg ccgcctggct
      901 ctctatggtc ttgaccgtct gatagaagct aaaaaagaag atctgcataa tctgacaggt
      961 cctatgactg aagcccgcat tcgtcttcgc gaagaagtag ccgagcaaat caaggccctg
     1021 aaagagatta aagtattggg cgaatattat ggtttggatc tgagccgacc ggcatatacc
     1081 gcacaggaag ctgtacaatg ggtgtatatg gcttatctgg ctgccgtaaa agagcaggat
     1141 ggtgctgcca tgtcactggg taatgtatct tcattcctcg acatctatct tgaatatgaa
     1201 ttaagccagg gtacgataac cgaaacattc gctcaggaac tgatcgacca attcgttatc
     1261 aaactccgta tggtacgcca cttgcgtatg cagtcgtaca acgatatttt tgcgggtgat
     1321 cccacatggg tgaccgaatc tatcggtgga cgtttcaatg atggacgtac caaagttact
     1381 aaaacttctt tccgcttctt gcagacactt tataacttag gcccgtcacc ggaacctaac
     1441 atgactgtac tatggagccc tgagttaccc gaaggtttca aagcattctg tgcacaagta
     1501 tctatcgaca cttcttccgt acaatacgaa aacgacgacc tgatgcgtga agtccgtcaa
     1561 tcggatgact acggaatcgc ttgttgtgtt tcatatcagg aaatcggaaa gcagattcag
     1621 ttcttcggtg cacgtgccaa ccttgccaaa gccctgctac tggctatcaa cggaggacgt
     1681 tgcgaaaata caggtacagt tatggtaaaa gacatccctg tattgaccgg tgaaacactg
     1741 aagttcgaag aagtaatggc caactataag aaagtattga tacaaattgc acgtgtatac
     1801 aacgaagcaa tgaatatcat acattacatg cacgataagt attactacga aaaggcgcag
     1861 atggctttcg tggatactga tccccgcatt aacctcgctt atggtgtagc cggactttca
     1921 atcgccatcg attcactgtc cgccatcaaa tatgcacatg tgaaagcccg tcgcaacgac
     1981 atcggactga cggagggatt cgatatcgaa ggtgctttcc cttgtttcgg taatgacgat
     2041 gaccgtgtag accacctggg tgtggacctg gtatatttct ttagcgaaga attaaagaaa
     2101 ctccccgtat ataagaatgc ccgtcctacc ctttcgctgc tgactatcac ttcgaacgta
     2161 atgtatggca agaagaccgg tgccactcct gacggacgcg ccaaaggcat tgcctttgct
     2221 cccggtgcca accccatgca cggacgtgat aaaaatggtg caatcgcctc actgagttct
     2281 gtagccaagt tgcgttatcg cgactcacag gatggtatca gcaatacatt ctcgatcgtt
     2341 cccaaatcat tgggagcaac acaagaagac cgtatcgaca atctggtgac catgatggac
     2401 ggatatttta caaaaggcgc acaccacctg aacgtaaacg tgctgaaccg ggaaatgttg
     2461 caggatgcga tggaacatcc cgaaaagtat ccgcaactga ctatccgtgt ctcaggatat
     2521 gccgttaatt tcgtgaaatt gagccgcgaa catcagttgg aagtaatcag ccgcagtttc
     2581 cacgaaagaa tgtaattgaa tgataaacgt acactcatac gagtcaatgg gaacattcga
     2641 cgggccgggt ctccggctcg tcgttttcct tcaagggtgt aacttccgtt gcctctattg
     2701 tgccaatccg gacacaattg aagccaaagg agggacagca accgaccctg aggaaatagt
     2761 tcgcatggcc gtcagtcaga aagctttctt cggtaaaaag ggaggtatca ccttttccgg
     2821 cggagagcct acttttcaag caaaatcgct tatcccactt tttaaaagac taaaggaagc
     2881 aggaatccat atttgccttg ataccaatgg cgggctatgg aacaatgatg tagaggaact
     2941 attggaattg actgatctgg ttttattaga tatcaaagaa tttaatccgg aacatcatca
     3001 gtctttaacc ggaagaagca acgagcagac cctgaaaacc gcagcctggc ttgaaaccaa
     3061 tcataaacca ttctggttgc gatacgtatt agtgcccggc tacagtgact tcgaagacga
     3121 tatccggcag ctgggagagc atcttggaac gtaccagatg attcagcgtg tagaaatatt
     3181 gccttaccac accttgggtg ttcacaaata tgaagcaatg aacaaagaat atatgctgaa
     3241 aggagtgaaa gagaatactc cagagcagat agaaaaggct gagaaactat tcaggcaata
     3301 tttccagacc gtacaagtaa attgacttat ataagtgtcg aaattcgtat tcaccacaga
     3361 ttacacgaat ttacacaaat aaagatcatt ggcaatcaat agattaagtt cattctgcgg
     3421 tgaattatga cgactgcact tatttataat tttgtaagtc acgatataaa agtctccctg
     3481 ttcttgcctt aattcattac aatacaaggc aagaacaggg agataatgta accggcatat
     3541 tttttgccat cctactttaa taagtgaatc gcaatcctgc ctgcaagtta aagttacaag
     3601 gcctttcttt tcggatggtt tgtactttgg agccatcatc aaagaaatac gaaactcccg
     3661 gttccacata taggccgaca tgatctgtcg cattgaattg cgctcccacg gcaccggcta
     3721 cagaaaattg caaaggcttc acattcacct tatcatccgc caactttcca taaacacact
     3781 tttcaaccat tcctccggca gatacataga gtgtaaaata tttcttttcc agaaaattcc
     3841 agtttccacg tacaggaata cctatataat gcaatttctg actctgcatc ttggtatccc
     3901 cctgccgttt gatgtcagaa gacaacaacg tataagtcaa tcccgtctct acagagaaac
     3961 ctttgggaag agacttacgt acagacagtc cgaagctaac cggctgatga tgttcataat
     4021 ccaccacggc agttgtattg gacttcaggt aagggactcc ttcttcaaat ataacttcct
     4081 gatcggcagg aatactcaca gctccattca tgatcgtcat caagtcgacc ctgttagtca
     4141 tcggacgggg cgcaaaattt tcggaaccat ttgtcggaag tccacctcca ttaccgatac
     4201 ccactcccat cgaccattta ccaccacgtt tagcagaaga gtctccgata ggcaactgat
     4261 acttgtcttt accggacggt cgccgcgctt ctttcctctt tggaggctgc gccgtcgcac
     4321 tttctttttt ctcgattgca gcaattgctt cctgttgcgg ctcagatctc ttttcctccg
     4381 tcactgcctc cggtcgcttc tctaccaggg aggatacctc cggaacaatc accggatcag
     4441 tattctttgc caaatagccc gaaacagggt taatactcgt cgttcctacc ggcttaactg
     4501 gttcggatac agctacctgt acatccggca aggcaggttc cggcaataca tccgggttga
     4561 cagccagtga aggagccgtt gcataacgga tttcatcagc taccggacta ttcagaaaat
     4621 acaaactgac agcagtcgtt accaccaata ccacagctgc cgcagcaacc gcccaccggc
     4681 gatacggata tattcgtttt tcggttacag gcatcagttc cctttccagt cgttcccaac
     4741 cggaagcagg catcggctcc gaataatctt cgagcttatc cttgaatgct ttaatccatt
     4801 tttcgtcttc tttcatcatt ctatttcatt tttgaaatcc aaggttcacc tcagtatctg
     4861 taaatacatg tcaaccattg gtcaccaacc attctttcac tttctttgcc aatacacttt
     4921 ttgcgcgaaa aagctgtgag gcagaagatt tttcattaat ccccaacatc tgtgcgattt
     4981 ccttgtgcga cttatcttca aaggtgtata aattgaatac ggtacgatat ccggcgggga
     5041 gttcattaat aaattgcatc agcactttct gtggtattgc ttcaacagcc gaagcatccg
     5101 gttcttcata cgtttcggga acttcatcca gtgccgtggt ctggttcatc acgtcgttct
     5161 ttcttaagaa ctgtaaaacc gtattcacca ttacacgctc catccatgct ctcagagagc
     5221 cttcaccccg ccaggtaaac ttgtcgaagg agtcgaaaat cttcaggaaa ccgtcgtgta
     5281 ccaagtcttg tgccatgtcc ctgtctccgg cataacgaag acagacacca agcatgcgcc
     5341 ctgcgtactg ctcataaagt tctttgcggg cacgattatc tccctgcctg caacgttccg
     5401 acagctctaa ttcattcatt ctcctaaaca cgtgtttacc ttataaatgc agcaaagata
     5461 gaaatactgc acagagagaa caactctttt atcacttttg tttctttaac attttaggat
     5521 gcaatatttc atcacttcct gcattttctc aatacaataa agaataaatc tcaatggata
     5581 aataggataa aaccaacaag aaacttatga agaaatttaa tttaataact tttgccgtca
     5641 tcctgatgtt attgcccatt ttacagtcat gtctggacga tgccaacaac gacgagtggg
     5701 tcacttgtcc tccgggtgga atattggcca tcggcacaat gaagattccc aatgcggaca
     5761 ctccaaggga ctttttcatt gcattggaca atggagacaa tgtacttccg gcagatacgg
     5821 ccgatatacg caacaggaaa tacactgttg cagaaggtca aagagtcttc gttggctatc
     5881 tgcagatggg agaagagaaa cctggatatg agaacggtaa aatattcacg atagaagata
     5941 tattgacgaa agagatcatc ccactgacgg aagctacagc agacagcatt ggagacgacc
     6001 gtatcaacgt cacagcgcat gcacttacga aagattatct gaccatcgaa tatcaatatc
     6061 tgggcagcat gaatgaaaat aaaaaacaca tgctgaactt ggtacaaaac gaaataacag
     6121 gtcccataaa agatgacgga tatatctatc tggagttccg gcataatgcc tttaatgact
     6181 cccccaatca attgggttcg agccttgttt ctttcaagct ggatagtata gccgagcaat
     6241 tggcgacagc caaaggaata aaactccgtg tgaacaccat ttatgacaat atacagtatg
     6301 tcacaataga tatcaacgaa gacaaaaact taaaaataaa atcatttcat tctcaataaa
     6361 acaacaagaa acacctacac aatcaggcaa aacgagtaat aattctgata cataaaagaa
     6421 ataaggcggc gatgtttgtg aaaatatcgc cgtcgttttt atattatacc agacactgaa
     6481 cggcctgcag ggtaagcatc tccttgggaa ccgccgcctg aatctcctct ttcaaaacct
     6541 gcagcagact ggtgcggatg aagtctttcc gggtcaccag gacaatctga cgggtaggcc
     6601 gcgggatagc aaacggacgg accagttctt tctgctcttc gctcaattgc atcactgcca
     6661 gttcgggaat aaacgtaatc cccttaccac tctctaccat atgcataaag gtttccatac
     6721 tacccagccg atacgccatt tggctgatct taaccgcttc catctgacaa aaacgaacca
     6781 actgatcgcg gaagcaatgc ccttcgtcaa gaagccaaag ccgttcccct gtcacatcgg
     6841 acgtacgaat cacatcgtgc ttgaacaacg gttccttctt tgagacatag cccaggaatt
     6901 gctcgtagaa taaggtctct tccgttaatg cggcatcatc cagcatgctg gcaatgatag
     6961 cagcatccgc ttcaccggtc agcagagcct tgcgaatgtc gggcgtcttc atctccatca
     7021 cccgtatatc aagatccggg tatttctcca tcagttgcgg aaagaaacgg ggcagaagat
     7081 aaggtgcaat cgtcggtaac actgccaatc ggaatgtacc cgacagggag tgctgttctt
     7141 cgctgatgat ctccttgaca cagataactt ccgaaagaat cttacgggcc tgttccagca
     7201 ctttcttacc aatggcagta gggcaaaccg gtgtcatgct acggtcgaac agtttcaccc
     7261 ccaattcgtc ttccagcttt tggatcattg cactcaaagt aggttgcgtc acccggcaat
     7321 actcggcagc tttagcaaaa tgccggaact ggtccacagc cagaatatat tccaattgtt
     7381 gtatagtcat cgttctctga tttattaaag atatagaatc tatcaatgca aagatagaaa
     7441 ttttcagttt gacacgaatc attttgtgcc gtatctttgt tccagataaa aagaagaaat
     7501 atagtattaa ctcaaaaaaa acaatatcat tatgaagact ttaaattata cacatttgga
     7561 agaaaaagga gctaacacca tcgtactgtc attacagcaa ctgcttgccg attttcagat
     7621 tcattatgca aacctgagag gatttcactg gaacatcaaa ggacacggtt tcttcgtact
     7681 gcacagcaag tttgaagatt tatataatgg agccgccgaa aaggtggacg aaatagccga
     7741 acgtatactg atgctgggag gaactcccgc caataaatac agtgactatc tgaagatggc
     7801 gcagatcaag gaagtggacg gagtgaataa ggccgacgac gctctgaatc atattctcga
     7861 aacttacggg catctgattg cggaagaacg taaaatcctg tctctcgcct cttcacacaa
     7921 cgacgaagta acagtggcca tgatgagcga ctacctgaaa gaacaggaaa agatggtttg
     7981 gatgctgact gcatacaacg gataacagcc gaaagggtgt agccatctga ccgaaaaggt
     8041 gtagccatac aagcaaaagg gtgtagccat cccggcggga tagctacacc ctttctgttt
     8101 tattcgattc agatgatact tgtacgtttg gtaaattcaa taatctccgg aatgtatccg
     8161 aatgcgagcc cggtcactgt atccgcacac ccataataga tggcaatccg tccggtctcc
     8221 gaatcatgaa gcgccgcgca tgggaaacag acattaggca catcacccat acattcgtaa
     8281 tccttctgag gtgaaatcag ataaggcccc gaacggaatt ttactttcca gggttgatcg
     8341 atgtcaagca gtgccgaacc aaaactatac acaaaaccgt tgcaggaagc caatacacca
     8401 tgatagatca gcaaccagcc ttccgaggtt tcaatcggga taggccctgc accgatcttg
     8461 gtacactgcc aggcactgtc ttcgaacgga gccggcgaca taacatgacg atgacgtccc
     8521 caaaactcca tatcgggaga ctcgctatag aaaatatctc caaaaggagt atgcccatta
     8581 tcactcgggc ggctcaacat cgcaaaacga ccgtttatct tacgagggaa caagactcca
     8641 ttccgattga aaggaataaa ggcattctcc aactggtgaa aagtaacaaa atcataggtg
     8701 taggccacac cgatagtagg accatgatag ccattacacc aggtcacata gtagcggtct
     8761 tcgataaagc aaacccgtgg gtcatatcca tagacccagg ttccaacctc agcatcatca
     8821 cattgaaact ttaacggttc ttcgttgata tcccaatgaa cagcatcctt gctgaatccc
     8881 acatgcaaac gcatgcgacg attagtatca tcacaacgga acacccctgc atagccatcc
     8941 ttaaacggaa ctacggcact gttgaatata ctgtttgaag tagggagcaa gtcgcgcgga
     9001 ataatcggat tggccgaaca acgccacact acatctttac atcctgccgg acgttcttcc
     9061 caaggcatag ccggcaaagc agcacctgca attttaattt cttccatgat tcgattaaat
     9121 taatattatg tatatatctt gtttatattg aaaatctctt tttatttctt ctttccgtcc
     9181 ggatatgtga aaggtaccag ccaagtcacg ataaaagccg gtatggtagc gataagtacc
     9241 cagataaaga aatcgcgata acccagccaa tcgctcaggt atccgctcat cattccggga
     9301 agcatcaccc ccagattcat aataccggta gcaaaagcat aatgtgccat ctgatgtttg
     9361 ccgggagcca cttgctgcat cataaagagc atcaatccga caaaaccaaa cccgtaaccc
     9421 aagtattcag acacaatggc cataccaata atccatagat cggaaggctg gtaaagggct
     9481 aacaggaaat ataccaagaa cggaatatta aaagcgcaac ataaagaaaa caaagtcttc
     9541 cgaagtccga aagccgaaat gtaataaccg gccaaaagcg aaccgagaat aaaagctccc
     9601 gctccgaacg taccatatac cagtccgata tcctgagtgc tgagtcccaa tccaccatcc
     9661 gcaaccgacg ctttcaggaa caacggtaca atcttgatgg catatccttc ggcaaaccgg
     9721 tacaaaatga taaagacaat gtagaaagca atatgttttt tttggaaaaa agagcggatg
     9781 acttcccaaa gcatattcaa tgcgtcactc atcgtattca cttcaccgga agcgcctcct
     9841 cccgaaggca aaatccggat gtggtaaaga ccgatcagaa tcataatacc cgcacacatc
     9901 aacatgacaa tcatccaggc atgtaccact ccaaattcat ccttcagcat acctgccagc
     9961 caaaccaagc ctccgttggc aagtatcttg gccagattat aaaaagctcc ctgccaaccg
    10021 atatacttgg cttgctgggt agcagtcagt tcagtcaggt atactccgtc acccgcaatg
    10081 tcatgagtcg caccactgag agcaatgatc cccatcagag cgatggcata acgaaaaaag
    10141 tcgggcagcg gcagcgaaag tgctaccaat gcaaatgcca gtccggtaat gatttccgta
    10201 gcgacaacaa agtatttctt cgttttaaac atttccagaa acggactcca taaaggcttc
    10261 aatgtccagg gaagcataat gagagaagtc cagaaagcaa tctgtgcatt cgacacttcc
    10321 atatcggaaa acataaggac agaaaccatc gaaagggcca caaacggcaa tcccatagca
    10381 aagtaaacag taggcaccca acatacaggg cttatcggct ttttattcat cagttagttt
    10441 tttataataa ttccatcggt taacaattcc agtaagcaaa gataggggat attaaaaaca
    10501 taacccaaga ttacgacaag aagttgcttt cattatttaa taatacaact cacccgggaa
    10561 aactactaac ctctatcacc ctttttttat taaactttat caatacaata cacgcaaaga
    10621 agcaccgaag actttcatcc ccgatgcctc tcgccccctt atctacaatc taaacacctc
    10681 tattgcttca catataaatt tatctcagca aacccggtat aattatccgg agtcagacag
    10741 tttattctga attcctttac attcgggata ggtggttcga tggccgcata ttgcggatca
    10801 gcccctttaa aatttctgaa agtcaagact ctcgggtaag taacccactc ggtttcaccc
    10861 tctttccgaa ccttaatctc agcacttctc agattataac ccgatccgta ggcactctgt
    10921 ttagtgaccg aaaatccggt taaggtaaca ggccggtcca gtaccgtatt ccaccaacac
    10981 tctccggcat tagccactcc ccatgtaaac caagtagtat ttatctcacc gtcaatagcc
    11041 agatgtgcac catatttggc atcatcatcg gcataaacat tgctgcaact tacactccac
    11101 gcactgcaat ctacagcgga ccaattcccg ggtttcgtat aactggtata aagcacgctg
    11161 gtataaatcc ggatataaac cgtcttcata gatgtactga cagcctgttc gtccatgccc
    11221 gtaactcctt taagcgtcac gggaagcaca tatccgtcag gattagtcaa cttttctata
    11281 ttcttcaaaa cgacctgaaa agatgaatcg gccactgtct gtcccgtttt taagacaact
    11341 tcacttgttt caatagtata attatcttgg ggcaacaact tacatttcgt cttattggca
    11401 gaattgtaag tatccacttt cagcgtatct actcccaaag cggcagtgac atcccgcgta
    11461 accggctgta cggcacacaa ttgtatttca aaatcagaac ggtcggcagt agaggaattg
    11521 ctcacacaat ccaccactac cgcagcaccc atttcggccc ccggtgcaac tcccgttctg
    11581 atatatatct tttgatattt gtccatttca tcatcatcgt tgctgcacga agccaacgat
    11641 acaaagcctg ttatcaggca gattaaggtc acaaaattca aatgtctatt catatcttat
    11701 cttcttttta catagttatt gcttatcaaa acgaacatgc tctttccaga caagagttcc
    11761 tcctgccacc aaatcgtatc cgtgtccggt acagtcggca aaggcatttc ctttaccttc
    11821 atccattttc caatagccta tcaggttcgg atcggcgggt ttcacggcaa aatacatgtt
    11881 ggactgaatt tgcgtctggc tgattgcgct cttccaaaga cgcacctggg ccatctgaca
    11941 attgttgcgg aagtagctac cgctcgaaac catgttcatc ttgtcgaatc ttaccgggcc
    12001 accctttgtc tgcagagtca cgtcgagcac tccgttgata taaatcgaca ataacccgga
    12061 agaattataa acgaaggcca gatgatacca cttattcttc tcaaacaaag tcaccgtatt
    12121 gacctgactt ccaagtgtct tcacctgtaa tgaattataa gggatcatag cgtcaccgaa
    12181 acggatataa acctcgtggt cgctgctgcc cgaattaaat atagcctgat tattaatatc
    12241 gaatccgtcc atctgtaccc aagcctcgag tgaccattca ttggttgtca ctccccacaa
    12301 ttcgtccttg gcgggcttca cggcattggt cgtattcata aacggtacag actgtatcag
    12361 cggcttatcc agcaaaatga taaacttcga cgaaagcccg attgtggaca ccggtccctg
    12421 aatttctgtg agagataccg gaatagcata caattctccg ttttcgtttg aataaggttt
    12481 cactctaaac tcactgggga ttgcgctaac atcgcctgcc gctatcttta tctctttgtc
    12541 ataagtaaaa tactgctcgg gaaggacttc gtacgaagtt tcattagctt cattgtactc
    12601 tttaagaata gaaggatcta ccgtcaggac agcagtcaca ttttcggtta caggctgtcc
    12661 cacacgtacg gtcagagtag ttgttgttac attttcagga tcaacggtaa cctttgccga
    12721 accattctcg gatgcttcat tcaaataaat cgcattgtcg ataacctggt aatcggcatc
    12781 gttgcatcct gccaggatca tcggcagaac gaaacaggca agcaaacatt gttttattgt
    12841 tattcttttc ataatcaaat tctttaaagt cattttacag caggattcat tattctgatt
    12901 gcttcacgca ggtacttata ttcgatgtcg cccggatagt catattccat gtgataggtg
    12961 cctactccac ccttccgtac ctgttttccg tcaatagtcg gagtccagcg tgccatgccg
    13021 gcaagtgctc tcattttgtt tccgtaacga tctacataat cacctcctcc tgtcggagca
    13081 taagattcga aattctccgt aacgatgtac atattagcca ctttctccgg aggaagtatt
    13141 cctttaaagt tggcaatcgt accagccaga cgtctgtcaa gattagcgtc ggaattaccc
    13201 gcaaggttag agtatgcctg cacaatgaaa tagtcaaagt aaggcccggt ttccggatga
    13261 atactttgag gctcgccatc aatcacaagt aaccgtcccg tacccgattt aggtccgatt
    13321 ctttc
//
