LOCUS       c00226_gnlPro..         4245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OAOLEDGK_226.
ACCESSION   c00226_gnlPro..
VERSION     c00226_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:51:48
            Original ID  :: gnl|Prokka|OAOLEDGK_226
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4245
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1404
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg226_1"
                     /sec_met_domain="ILVD_EDD (E-value: 3.5e-168, bitscore:
                     548.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AMRLNIPTVFVSGGPMEAGEWNGQHLDLIDAMIKSADESVGDKEV
                     AQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHENRKKLFEDAARLIV
                     ENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLHLLAVAHEAGADFKMD
                     DIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGGLVDTNVHRVDGMTLA
                     EAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELDTDRATGCIRDLEHAY
                     SKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDAACDGILGGKVVSGDV
                     VVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHVSPEAAA
                     GGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNREVSKALKAYASMVSSA
                     DKGAVRLID"
     protocluster    1..4245
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3833]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3833
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4245
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1489..3240
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg226_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-47, bitscore:
                     149.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRVFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIEEMIVTDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             3273..3833
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg226_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.4e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             3830..4243
                     /locus_tag="ctg226_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDY"
ORIGIN
        1 gctatgaggc tgaatatacc gactgtgttt gtttcaggcg gtccgatgga agccggggaa
       61 tggaacggac agcatttgga tttgattgat gccatgatta aatctgctga tgaaagtgtg
      121 ggcgataaag aggtggcaca gattgagcaa catgcctgcc ccacttgcgg atgctgttca
      181 ggcatgttta ccgctaattc catgaattgc ttgaatgaag cgattggatt ggcactgccc
      241 ggtaacggca cgattgtagc cactcacgaa aatcgcaaga aactatttga ggatgcagcc
      301 aggttgattg tagagaatgc ctttagatat tatgaagaag gggatgagag tgtactcccg
      361 cgcagtattg ctacccgcga ggcatttttg aatgccatga cgctggatat tgcgatgggc
      421 ggttccacta atacggtact tcatttgttg gctgtggctc acgaagccgg agcggatttt
      481 aagatggacg acattgacat gctctcccgc aagaccccct gcttatgcaa ggtggctccc
      541 aatacccaaa agtatcatgt acaagacgtt aaccgtgccg gtggcatcat tgccatcatg
      601 gatgagcttg ccaagggcgg attggtcgat acgaatgtcc atcgtgtgga tggaatgacg
      661 ttggcagagg caatcgaccg gtatagtatt accagctcta atgtatgtaa agaggcaatc
      721 aagaaatact ccagtgcggc agccggaaag ttcaatctgg tactcggctc acaaaatgcg
      781 tcttataagg aactcgatac ggaccgtgcg accggttgta tccgtgattt ggaacatgca
      841 tacagcaagg atggcggtct ggcggttttg aagggaaata tagctcagga cggttgcgtt
      901 gtcaagactg ccggtgtaga cgagagtatc tggaaattta cggggccggc gaaagttttc
      961 gactcacaag atgcggcttg cgatggtatt ttgggtggaa aggtagtcag tggagacgtc
     1021 gtcgtcatta ctcacgaagg accgaaaggt ggaccgggta tgcaggagat gctttatcct
     1081 acttcttata tcaaatcccg ccatctgggt aaggagtgtg cattgattac tgacgggcgt
     1141 tttagtggtg gtacttccgg actgagtatc ggacatgttt ctcccgaagc ggctgccggt
     1201 ggtaatatcg gtaagattaa ggatggggat attatcgaaa ttgatatacc gaaccgttct
     1261 atcaatgtga agttgacgga tgaagagctt gcagcacgcc ctatgactcc ggtaacccgc
     1321 aaccgtgaag tctccaaagc attgaaagca tatgccagta tggtgagttc cgctgacaaa
     1381 ggggctgtga ggttgattga ttaaaggcct cacccccgac ccctctccga aagagagggg
     1441 aggagggaat gatacaaatt tccgaagttt ttaataaaaa gataaagtat ggctgataat
     1501 aataaaaaga gtaacttttc ctccctctcc caaggagagg gtcggggtga ggctctaata
     1561 acaggcgcag aagcattgat gcgctctctg gagcatcagg gagtaaagac tattttcggt
     1621 tatccgggag ggagcatcat gccggtattc gatgccttat acgaccaccg gaaggaattg
     1681 aaccatatcc tggttcgcca tgaacaagga gccacccatg cggcgcaagg ctttgcacgt
     1741 gtgtcgggcg aggttggcgt ttgtctggtt accagtggac caggtgctac caatactatc
     1801 acgggcattg cagatgccat gattgacagt acgcctatcg ttgtcattgc cggccaggta
     1861 gggacgaact tcttgggtac ggatgcattt caggaagtgg acttggtagg cattactcag
     1921 cctatcacga aatggagtta ccagattcgt cgtgcagaag atgtggcctg ggcagtggca
     1981 cgtgctttct atgtggcaaa gagcggacgt ccgggaccgg tcgtgctgga ttttgctaaa
     2041 aacgcccaag tggagaaaac agaatatgcg cctactaagg tggactatgt ccgtagctat
     2101 cttcccgttc ccgaaatgga gccggaggcc atacggaagg ctgctgaatt aataaatggt
     2161 gcggaacggc ctttggtgct ggtaggacaa ggcgtggagc tgggagaagc ccagcaagag
     2221 cttcgtgttt tcattgagaa agccggaatg cctgccggat gcactttatt gggactttcc
     2281 gcattaccta cgaaccatcc gttgaacaaa ggaatgcttg gtatgcacgg taacctgggg
     2341 cccaatatca ataccaataa atgtgatgtc cttatcgccg taggcatgcg ctttgatgac
     2401 cgtgtgacgg gtaaattgga aacatatgcc aagcaggcga agattatcca ctttgatatt
     2461 gaccctgccg aaatagataa gaatgtaaag accgatgttg ctgtcctggg agattgcaaa
     2521 gagacactgg ctgccgttac ccaattgctg gaacccgcca accatcagga atggattgac
     2581 agtttccggc aatacgagga agtggaagag gaaaaggtaa tccgtccgga attacatccg
     2641 gcaggaaaag cgctaagcat gggtgaggtg gtgcgtgctg tgagtgaggc tacccataac
     2701 gaggcgatat tggtgactga tgtcggccag aatcagatga tgtctgcccg ttatttcaaa
     2761 tacagcaagg aacgtagcat tgttacttcc ggtggcctgg gtactatggg cttcggcctt
     2821 ccggcagcta tcggtgccac ttttggacgt ccggaccgca cggtatgcgt attcatggga
     2881 gacggcggct tgcagatgaa cctgcaggag ctgggtacca tcatggaaca aaaggctccg
     2941 gtgaagatga ttctgttgaa caataacttc ttgggtaatg ttcgtcaatg gcaggcgatg
     3001 ttcttcaatc gtcgctattc gtttactccg atgatgaatc cggattatat gaagattgct
     3061 tcggcatatg atattcctgc acgcagggta atgacccgtg aggagttggc aaaagcgatt
     3121 gaagagatga tagtaactga cggaccgttc ctgctcgaag cttgtgtgga ggaagaagga
     3181 aatgtaatgc cgatgacacc tccggggggt tcggtcaatc agatgttgtt ggaatgctga
     3241 agtcatgcga aattaaagaa tttactctat ctatggataa aaaactatat acaatcattg
     3301 ttcattcgga aaactttgcc ggtttgctga atcaggtgac ggctgtgttt acccgccggc
     3361 agataaacat cgagagtttg aatgtatcgg cctcctccat caagggggta cataaatata
     3421 ccattaccgc ttggacggac aaggatacca ttgaaaaggt gaccaagcag attaccaaga
     3481 aaatagatgt gctgcaagcc cattatttca cggatgatga aatctatcag cacgagattg
     3541 ccctttataa aataacgacc cctacgctgg aagaaaaacc ggaggtgtcc aaagtaatcc
     3601 gtaagtacaa tgcccgtatt gtggaggtga atgctgtatt tgccattgtt gagaagaatg
     3661 gcatgagtga ggaaataacc aatctttatg aggagttgcg ccagttggat tgcgtacttc
     3721 agttcgtccg ttcgggtcgc gtagccatta cgaccagctg ttttgagcgt gtcaatgaat
     3781 atctggcgga ccgtgaagca aaatatcgtc aaagtaaaca ccaagaatca tgatgagcga
     3841 gaacaataag ataggtacct acaagtttgt tgccgaaccg tttcatgtcg actttaccgg
     3901 acggctgaca atgggagtat tgggcaacca tttgttgaat tgtgcgggtt tccatgccag
     3961 cgaccgcggt tttggcatcg cgactctaaa cgaggacaat tatacttggg tattgtcccg
     4021 tctggctgtc gaactggatg aaatgcctta tcagtacgaa gatttctcca ttcagacttg
     4081 ggtggagaat gtctatcgcc tttttacaga ccgtaatttc gctatcatcg ataaggaggg
     4141 caagaagatt gggtatgcac gttccgtttg ggcgatgatt agcatgaata cccgtaagcc
     4201 ggcagatttg ctggctcttc atagtggcag cattgtagat tatgt
//
