LOCUS       c00129_gnlPro..         6505 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PGLABOLB_129.
ACCESSION   c00129_gnlPro..
VERSION     c00129_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:42:33
            Original ID  :: gnl|Prokka|PGLABOLB_129
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6505
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6505
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[896:6503]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      897..6503
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6505
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6505
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..548)
                     /locus_tag="ctg129_1"
                     /transl_table=11
                     /translation="MNTTTTTTTAAAKRSSTLYMVELAMMIAIILLMSFTPLGYLRTPG
                     LSITLLTIPVAVGAIILGPKGGAVCGLAFGATSFYMAVTGSSAFAAALFNINPFGTFIV
                     CIVARVLEGWLTGLIFAALYKSPAKKFSYYIASLACPLLNTFFFMGFLCLFFYNTDYIQ
                     GIVSSLGVSNPVVFVAAFV"
     CDS             complement(897..1256)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_2"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-23, bitscore: 70.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIK
                     VFNCSREDKAELFQIAETFKAKVIDYGKDSLLLEFVQTAIKNDAVVKLIKEEFHRIEVV
                     RGGSVGIESISMMER"
     CDS             complement(1457..2170)
                     /locus_tag="ctg129_3"
                     /transl_table=11
                     /translation="MYLSDIHTHSIASGHGTTCTISDMAKAASKKGLKLLGISDHGPGT
                     LASGTSSYFRSLPFYPRKRFGIDILYGVELNILDSAGHTDLSDELLNNLDYAIISMHRQ
                     NYRSGSVSQNTEAYINAMKHPAVKILGHCDDTHFPVDYETLARAALRENVIFEINEASL
                     APGGYRGDTRANAARILYLCQKYQLPVILSSDSHGKEHVGDFTYAEEFVHQLMFPETLI
                     LNNQLPRLKVFLQTR"
     CDS             2933..4189
                     /locus_tag="ctg129_4"
                     /transl_table=11
                     /translation="VKSTERLIFHIDVNSAFLSWESARRVSQGLPDLREIPSCVGGDPK
                     KRTGIVVAKSIPAKKYGIQTGEPVAMALRKCPNLVIVPSDFELYDKCSRAFKAICASFA
                     PVMESFSIDEVFLDMTGTSLIYPDPVAAAHELKGKIHRELGFTVNVGISTNKLLAKMAS
                     DFQKPDRVHTLFPDEIPEKMWPLPIRNLLFLGKASEQKLLNQGIRTIGDLARERASNVQ
                     YWLGEKTGHQLWQYARGIDDSPVKAVPDEAKGFSVETTFNDDITSIEQVFPILLEQCDV
                     LATRMRRKDKKCNCISVTFRTLDFRNRSHQTKLENATDLTDEIYINATRLFKEFWKGQP
                     LRLIGVALTGLTDGTYEQMSLFEDTENKERHRKLDAAMDEIRMKFGNDKITRASIMNSN
                     ARIGRKAKAQMKNEKTEEP"
     CDS             complement(4258..4767)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_5"
                     /sec_met_domain="ALS_ss_C (E-value: 2.6e-23, bitscore:
                     70.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGMKKRWISLYVENQVGVLSKISGLFSGKCYNLDSLTVGTTED
                     PTVSRMTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIKVFNCSKEDK
                     VELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVRGGSVGIES
                     ISMMER"
     CDS             complement(4785..6503)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-49, bitscore:
                     155.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQISGNKLLVKALKEEGVEYLFGYPGACTIDISDELYKQDDVKI
                     ILPRHEQALVHEADAYARTTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVA
                     RHLIGNDAFQEVDIVGITRSITKYGVTVRRREDLGRIIKEAFYIARTGRPGPVLIDLPK
                     DVMAELGSAEYPKNVNIRGYKPNTDVHIGQLKRAIKLLNKAKRPLFLAGGGVVISRAHE
                     IFREVVEKTKVPVVTTVMGKGSIPTDHPLYIGNLGMHGAYAANMAVSNCDVLFSIGTRF
                     NDRITGKLHEFAPHAQIIHIDIDTASISRNIQVDIPIVADAKEAITKMNEYVQECSTDK
                     WLNLIKNWKEEHPLKMRPNDLLSPMDILKEINEQFENSIIVTDVGQHQMLVSQYAEITE
                     GKQMIMSGGLGTMGYGLPGGIGAKIGNPDRPVIVISGDGGVQMNIQELATAVLEELPVI
                     LCIFNNEYLGMVRQWQKLFYGKRYAMTNLRAGALSRRTEGMEYPQYTPDFIRLAESYRA
                     KGIRVTKKEEIAAAFEEAKKNTKAPTVIEFIIDPEEMVYPMIKPGGTLEDMIMDC"
ORIGIN
        1 cccacaaaag cagcaacgaa gacaacagga ttgcttactc caagactgga aacaataccc
       61 tgaatgtaat ctgtgttgta gaagaagaga cataaaaagc ccatgaagaa gaaagtattc
      121 agtaacgggc atgccagtga agcaatgtaa taggaaaatt tctttgccgg tgatttatat
      181 aatgctgcga aaataagtcc tgtaagccat ccttccagca cacgtgccac gatacataca
      241 ataaaagtac caaatggatt gatgttgaaa agtgcggcag caaaagctga acttcctgtg
      301 acagccatat agaagctggt tgcaccgaaa gcaagtccgc atacagcacc acctttcggt
      361 ccgaggatga tagctcctac agctaccggg atggtgagaa gagtgatgga taagccggga
      421 gtacgaaggt agcccagcgg ggtaaaggac atgagcagaa taatggcgat catcatagcc
      481 agctctacca tgtaaagagt gctgcttctt tttgcggcag ctgttgtagt ggttgttgtt
      541 gtgttcatat gaattctcct tttggtctga taaaacggcg caatgcgtcc cctgcttttc
      601 agacagttta gagtatgggg atcaggcgtt atgaaaaata tacatcagaa caaaagaaaa
      661 atttccggtg tgtagacgcc ttataggtcg cctcacaaat ttaaccagac tgtgaagtgg
      721 atgactttat ccaccagact gtcagatgtg gaaatcagat gcattttctt tcgaataacg
      781 ctcccgtaaa caataacaca tttgattaaa aactgcaata ttttatagta tgtttgaaaa
      841 taaatacagg atatagagac gtttctatat tctgcaaaaa atattgatta tgagatttag
      901 cgttccatca tgctgatgga ttcaattccc acacttccac cacgtactac ttcgattctg
      961 tggaattctt ccttgatcag tttgacaact gcatcattct tgatggctgt ctggacaaat
     1021 tccagaagca ggctgtcttt gccgtagtca atgacttttg ccttgaaggt ttctgcaatc
     1081 tgaaacagtt ctgctttatc ttccctggag cagttgaaaa ccttgatgta gagaatttct
     1141 ttcattctga caaatacatc tgtgaagtcg attaccttga taacctcgat catgcggttt
     1201 aattgttttt tgatctgttc aaaggtttca tcatcgctga ctgttgcgat agtcattcgg
     1261 gatactgtag gatcctcggt ggttcctaca gtaagactga tctatcacga gatatgtaaa
     1321 tggttaagtg agttttgtta attaaaatgt actaaaatgt cgtctttttt gataagaaat
     1381 tatagaaaat aaacaaaata acacaatgca aaaaacaatg cataaaataa aagaatgtcc
     1441 ctttgagaac attcttttaa cgtgtctgaa ggaaaacttt taatctggga agctggttgt
     1501 taaggataag agtttccgga aacatgagct ggtgaacgaa ttcttcggca taggtgaaat
     1561 ctccaacatg ttcttttccg tggctgtcgc tggacaaaat aacaggaagc tgatatttct
     1621 gacagagata caggattctg gctgcattgg ctcttgtgtc tccccgatat cctccgggtg
     1681 cgagggaagc ttcgtttatt tcaaaaataa cattttcccg taaagctgct cttgccagcg
     1741 tttcataatc tacagggaaa tgtgtatcgt cgcagtggcc gagtattttt acagcaggat
     1801 gtttcattgc attgatgtaa gcttctgtat tctgagatac agagcctgaa cggtagttct
     1861 gccgatgcat actgatgata gcgtaatcca agttattcag cagttcatct gacagatctg
     1921 tatgtcctgc actgtccagg atgtttagtt caactccgta aagaatatct atgccgaatc
     1981 tttttctggg ataaaaagga aggcttctga aataagaaga agttccggaa gccagagttc
     2041 ccgggccgtg gtcagaaatc ccaaggagtt tcagtccttt tttgctggct gcttttgcca
     2101 tgtcagagat ggtacaggtg gttccgtgac cgctggcgat agaatgtgtg tggatgtcag
     2161 aaagatacat tgtttgtctc ctttccagag cggtttctat atatgataag agccttacgg
     2221 gagatgcaaa gttgctgttt gatggtacat tcgttatatt caagtatgac agatgaggat
     2281 ttaaatgtca atgaggaaac aaaataaaaa caactgaaat acaacaaaaa tcaaataaaa
     2341 aacaacataa ataaatggct gatacatgtt aaattatgtt gacttcggga aaatgagaag
     2401 gtataatgga actatatgaa aacacggggg cttattgctg atcaatgaca gcgatagcac
     2461 tgtttgctta tgtgtagaca gttacttcat gagaagggag taacatggaa atatttcaaa
     2521 catcagacat tcccggaatt ctcttatgaa tggctggaga ctgaactgga tactggtatg
     2581 attccacaaa tatggacagc gaagaaattg ctcctaacct ttatgactaa tcgataagta
     2641 tatatcgaga ggaaatgaat tctcagaatt aagtaaaaaa agttaccggg aacaatgtga
     2701 ctggtagcga aatacagacg ccgcactgcc gtatggcaag tgcggcgttg ttgttcaaaa
     2761 ctctgatagc agagtgaaat caaacaaata taaatacagt aacagctcag acaagatgat
     2821 gcaaataaag acactttttt ggacaaacga ggttcttacc ctggagagca gatcagggta
     2881 aaatgaaatc atcagatatg aagagcgcaa ttcatatatt ggaggaagaa cagtgaaaag
     2941 tacggaacgg ttaatttttc atattgatgt aaacagtgca tttctttcct gggaatcagc
     3001 cagaagggtg agccaggggc tgccggatct cagagaaatt ccttcctgtg taggaggaga
     3061 tccaaagaaa cggacaggta tcgtggttgc caaatctatc cctgcaaaaa aatacgggat
     3121 tcagaccggc gagccagtag ccatggctct tcggaaatgt cccaatctgg tgatcgttcc
     3181 cagtgatttt gaattatacg ataaatgttc ccgggcattt aaagcaatct gtgcttcctt
     3241 tgcacctgtg atggaatctt tttccattga tgaggtattt ctggatatga caggtacttc
     3301 tctgatctat cctgaccctg tagctgctgc tcatgagctg aaaggcaaga ttcacagaga
     3361 gctgggattt acagtaaatg taggaatttc taccaataag cttttggcaa agatggcatc
     3421 agatttccag aagccggaca gagtacacac tctgttcccg gatgaaatcc cggagaaaat
     3481 gtggcctctt cctatccgta atctgctgtt tctgggaaaa gcttccgagc agaagcttct
     3541 gaatcagggg atccgtacca tcggtgatct ggcaagagaa agagcatcca atgtgcagta
     3601 ctggcttggg gaaaaaacgg gacatcagct atggcaatat gccagaggta ttgatgattc
     3661 ccctgtaaaa gcagtgcctg atgaggcaaa aggtttcagt gtggaaacta cttttaacga
     3721 tgatattact tccatagagc aggtgtttcc catacttttg gagcagtgtg atgttctggc
     3781 aaccagaatg cgcagaaaag ataagaaatg caactgtatt tccgtgactt tccgtacttt
     3841 ggatttcaga aaccgttcac accagacaaa gctggaaaat gctacagatc ttacagatga
     3901 aatttatata aatgctacaa gactttttaa agaattctgg aaaggacagc cgctgcgtct
     3961 gattggtgtg gcactgacag gccttacaga tggcacttat gaacagatgt ctctgtttga
     4021 agatacagaa aataaagaac gccacagaaa gctggatgca gctatggatg agatccggat
     4081 gaaatttgga aatgataaga tcacccgtgc cagtattatg aacagcaatg cacggattgg
     4141 gcgaaaagcg aaagcacaga tgaaaaacga aaagacagaa gaaccgtaag taaagggagg
     4201 actgagcatt aagaataatg cgacaatcct ccctttataa aaatttcaga aaaagtttta
     4261 tcgttccatc atactgatag attcgattcc tacacttcct ccacgtacca cttcaattct
     4321 gtgaaattct tccttgatca gtttcactac tgcgtcattc ttggttgctg tctggacaaa
     4381 ttccaggagc agactgtctt tgccatagtc aatgaccttt gccttgaagg tttcggcaat
     4441 ctgaaacagt tcaaccttat cttctttgga acagttaaaa accttaatat acagaatctc
     4501 tttcatgcgg acaaatacgt ctgtgaaatc aataacctta ataacctcga tcatacggtt
     4561 caactgtttt ttgatctgct caaaagtttc atcatcactg acagttgcaa ttgtcattcg
     4621 ggatactgta gggtcttctg ttgttcctac tgtaagactg tccaggttat aacattttcc
     4681 ggaaaaaaga ccggaaattt tggacagaac acccacctgg ttctcaacat agagagaaat
     4741 ccatcttttt ttcattcctt tatccataat aattttcctc ctgatcaaca gtccataatc
     4801 atatcttcca gagttccgcc tggtttgatc ataggataaa ccatttcctc agggtcaatg
     4861 atgaattcaa ttactgtagg tgcctttgtg ttcttttttg cttcctcgaa ggctgctgca
     4921 atttcctctt tctttgtgac acggattcct tttgccctgt agctctctgc aagtctgatg
     4981 aaatccggtg tgtactgtgg atattccatg ccttcagtgc ggcgggaaag tgctcctgcg
     5041 cgcagattgg tcatagcata gcgtttgccg tagaaaagct tctgccactg gcgtaccatt
     5101 ccaagatatt cattgttaaa gatgcacagg ataacaggaa gttcttccag aactgcagtt
     5161 gcaagctcct gaatgttcat ctgcacaccg ccgtcaccgg agataacgat gacaggtctg
     5221 tcgggatttc cgattttggc tccgatgccg cctggaagac catagcccat tgttcccaga
     5281 ccaccggaca tgatcatctg tttgccctct gtgatttccg catactggga gacaagcatc
     5341 tgatgctgtc ctacatctgt tacgataata ctgttctcaa actgttcgtt gatctctttc
     5401 aggatatcca tcggacttaa aagatcattt ggacgcattt taagcggatg ctcttctttc
     5461 cagtttttga tcaggttaag ccacttgtcc gttgaacatt cctggacgta ttcgttcatt
     5521 ttggtgatag cctcttttgc atcagcaaca atggggatat ccacctgaat gtttcgggaa
     5581 atggatgctg tatcaatatc aatgtggata atctgggcat gtggtgcaaa ttcatgaagt
     5641 tttccggtga ttctgtcatt gaatctggtt ccgatggaga acagcacatc gcagttgctg
     5701 actgccatgt ttgctgcata ggcaccatgc atgccgaggt ttccgatata aagcggatgg
     5761 tcagtaggaa tggaaccttt gcccattacg gttgtgacaa ccggtacttt tgttttttct
     5821 actacttccc ggaagatttc gtgggcgcgg gagattacta caccgccgcc tgcaaggaat
     5881 aaaggacgtt ttgccttgtt taaaagtttg atggcacgtt tgagctggcc gatatggaca
     5941 tctgtgttgg gcttgtatcc gcggatattt acatttttag gatattcagc gctgccgagt
     6001 tctgccatta cgtcctttgg aaggtcgata aggacaggtc ccggacggcc ggtgcgggca
     6061 atgtagaagg cttctttgat gatacgtccc aggtcttcac gtctgcggac agtaacgccg
     6121 tatttggtga tgcttctggt gattcctacg atgtctactt cctgaaatgc atcgttgccg
     6181 atgaggtggc gggctacctg gccggtgaag catacaagag gtacgctgtc atagttggcg
     6241 gttgcaagtc ctgttacaag gttggttgct ccgggaccgc tggttaccag acatacgccg
     6301 actttgccgg tggttctggc gtaggcgtcg gcttcgtgga caagggcctg ttcgtgacgg
     6361 gggaggatga ttttgacatc gtcctgtttg tagagttcat cactgatgtc gatggtacag
     6421 gctccggggt agccgaagag gtattctacg ccttcttctt ttaaggcttt gactaagagt
     6481 ttgttgccgg atatttgttt catat
//
