LOCUS       c00187_gnlPro..         4508 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PGLABOLB_187.
ACCESSION   c00187_gnlPro..
VERSION     c00187_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:42:33
            Original ID  :: gnl|Prokka|PGLABOLB_187
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4508
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1116)
                     /locus_tag="ctg187_1"
                     /transl_table=11
                     /translation="MRSLAVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNKYIVQRFFILILMAALGLASSITAQFFAAKASVGFATKLRQAVYDHVQRLSFTEL
                     DTLGTDTLITRLTDDINQVQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKK"
     protocluster    1..4508
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1510:4454]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1511..4454
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..4508
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4508
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             1511..2782
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_2"
                     /sec_met_domain="HGD-D (E-value: 1.2e-56, bitscore: 180.4,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAVDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVHQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             2775..4454
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_3"
                     /sec_met_domain="HGD-D (E-value: 3.7e-18, bitscore: 54.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.8e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPDGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKPHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADA"
ORIGIN
        1 cttttttaca gaaaaactga tatgggaaag actgggggca ccggctttgc tgtactcaaa
       61 ggttacgtca ttgaatacga tggcattttc agaaagtgat gcatcagcag ttgctgttgc
      121 aaggtccttc gatatctgag cagaatatgt ggaggaagag gggtaatcca tagtagattt
      181 cactttcagg atatctgcca cacgtcctgc gcaggctgca gatttgttca gggtgatgat
      241 cagggaggca agcttgatca gttccacgat catctgagcc atatagttat aaagggcaac
      301 aacctgtccc tgctgcatac cgccaagatt tacttctact cctgctttct ggatcagaat
      361 aacagtagca atattgatca gtacgtaagt gaccggattt aacaaagcgg aaagctttcc
      421 tacaaagaga tttaactttg tcagctcctg attgcgggta tcaaattctg caactgcctc
      481 tttttcgcgg cagaatgcac ggataacgcg gacgcctgta agattttctc tggtcagtcc
      541 ggttactgtg tccagttttc cctgtacttt tttaaacaga ggaatactga gaaacataat
      601 gacaaagaca accagaaaca gaaacgggat cgcaacagca aaaaccaggg cacatttaaa
      661 gtcaatggta aatgccatga ccatggaccc aagtacgata aacggacttc gaagaagaag
      721 acgaagcccc atgttcagtc cgttctggac ctgattgata tcgtcggtaa gtcttgtgat
      781 cagggtgtct gttcccaggg tatccagctc tgtaaaggac agacgctgta catggtcata
      841 aactgcctgt cttaatttag tggcaaagcc cacgctggct ttggctgcaa agaattgagc
      901 tgtaatgctg ctggcaagac caagagctgc cattaaaata agaataaaaa atctctggac
      961 aatgtatttg ttgtcatggt ttgcaatacc tacatcaatg atctgtgcaa tgacgatagg
     1021 aacgatcagg tcaaatacaa cctccagaaa tttaaaaaat ggcgccagga tgctttcttt
     1081 tttgtagttc tttaaataaa ctgccaatga acgcatttta aaaattcctt cctttcgtaa
     1141 aaatctttct tatattattc cttctttttt ttgaaaaata atacattcaa aagtgtatca
     1201 tttgagactt ttttgtcaag aagaatgtac aaaaacaggt gaactttgga gaaaattcgt
     1261 tactgttcac tccgttcaca gtaacttagc caaaattcat tccagattgc ctgcggcaat
     1321 ggaattttgg cttgtatgtc tcgggatttt ggcatattca tgccaaaaca cctcgcagaa
     1381 tagtggtgtg tgaacagtaa cgaaaattca acttgacttc caaaaaagat attattaaaa
     1441 tattccgtgg cactatttgt gcactgacaa ttgataaatt attattacca taatgaggaa
     1501 gagacagact atggagatta ttgagacatt tggtcattat gtggaaaatc tgacggataa
     1561 aaagcctcag tcagcccgcc ggctgttaaa aaccggctgg gaggcacaga atctgaagtt
     1621 ccgttatatg caggacaaga gactgatgcc tgcagacagg catcttgcaa atctgatgat
     1681 ggataccatg ctgcgtcccc ttcagaaacc ggaagattct gttattgtaa gcatttttac
     1741 tccctgcgaa atgatgcagg aggtgggatt acatccctat aatgtagaag gattttcctg
     1801 ctatctttct gcaagcaaag cagagagggc atttttgcag caggcagaga atcagggaat
     1861 tgcagagaca ctgtgcagtt atcacaagac atttcttggt gcagcgcaga aaggactcct
     1921 gccaaagccc aaatgtattg tttataccaa cctgacctgc gatgctaacc tgctcacctt
     1981 ccgtaccctg gcagattttt accaggtacc tgtatttgcc gttgatgtac catggaatca
     2041 gaccacagag aatgtacagt atgtggcaga tcagttaaag gatttaaaaa tatttctgga
     2101 aaaaaataca ggaaaaacaa tctctgagga cagattaaag gaacgtcttg cctgcagtaa
     2161 gcggactctg gagaattaca aaaaatatca gcagatgcgt gcagacagat atgtgccctc
     2221 tgatctggtc acacccttgt atgcaggaat gacaaacaat atccttctgg gaacagcaga
     2281 agaagagaag tatacacaga tgcttcttga agatattaag aaagcaccgg cagcgaaagg
     2341 gaaacacatt tactggatgc ataccatacc attctggtcg gatgcagtgc accaggagct
     2401 ttgcttcagt gagaaagccc agattgtggg atgcgaactt gcagaaacct gtgagccgga
     2461 ctttgatcct gagaatcctt ttgaagcaat ggcagaaaga atggtatatc attcactgaa
     2521 cggaagtgcc cttagaagga ttgaagccgg tatccgccat gcgaaacagg caggagcaga
     2581 cggtgctgtg tggtttggac attggggatg taaacatacg cttggtgcgg cacagcttgc
     2641 aaagaagaag ttcgaggaag ccggtctgcc ccttttgatc ctggacggtg acgggtgtga
     2701 tcgaagccat ggaggagaag gacagacttc caccaggctg ggagcttttc tggaaatgct
     2761 gggaggtgct gagaatgaat aaaacttatt atgtctgtaa atataccccc attgagcttc
     2821 tggaatctct tggcggggaa tgtgagaact ttaaccatat gccggatggc tttgaccttg
     2881 cagatcaggt ttcccatccc aatatctgtg gttttggaaa aacacttctg gaaggagtca
     2941 tggagggaaa aatcaaggaa cttgtcctgg tgagctgctg tgataccatt cggagtgtct
     3001 atgacattct gctggaaagc ggcaagctgg attttcttta tattttggat gtgcttcact
     3061 gtgacagtgc ctgcagcaga gagcgtatgg ctgtacagtt aaaagggctg gccaaggctt
     3121 atgcacagta caaaggcaca gagtttgatg ccggaaaatt ccgggctgct ttccatgcac
     3181 aggagaaaat cacaaagcct catattgcag tgcttggtgc cagaatgggg caggaattat
     3241 ttgaaatgac cagcaaggct atgccccttc ctgtagagaa tgatacctgt gtgcataacc
     3301 gttctgtggg aaatatactt ccaccggagg gtgcttcttt tgatgaactg atggactggt
     3361 atgcaggtga gattctgggg cagattccat gtatgcgtat gatggacccg acaggccgta
     3421 agaagcttta taatgatccg tctgttgcgg ggattattta tcatacagtg aagttttgtg
     3481 atttttacag cttcgaatat gctgagatca agaatcatac agatgtacct cttttaaaaa
     3541 tcgaatcaga ttatactatt cagagcagcg gtcagcttct taccagactg gaagcttttg
     3601 cagagagcat tcagcctgaa acactggagc agaccataga tggagacaca aaaggagaga
     3661 gaaaaatggg aaaaggttat ttcgcaggga ttgacagtgg ttccaccagt acagatgtgg
     3721 tgattttaaa taaagatcat gagattgtga ccagtattat cctgcctaca ggagcaggag
     3781 ctgctatcgg agcagaccgt gcccttgcag aagcattgaa ggaggccgga ttgcagagag
     3841 aagatattga tgcgctggtt actaccggat acggacgtac agctattaaa aatggtgata
     3901 agagtatcac agagatcacc tgtcatgcaa gaggtgcgca tttcctgaat ccggaagtcc
     3961 gtactgttat tgatattggc ggacaggaca gcaaggtgat ccgactggat gagaacggtg
     4021 cagttgcaaa ctttgttatg aatgacaaat gtgcggcagg aaccggacga tttctggaaa
     4081 tgatggcacg taccatggaa atgaatctgg atcagatgag tgaatgtggg ctggaattca
     4141 aagaagatat tacaatttcc agtatgtgta cagtatttgc agaatcagaa gttgtatccc
     4201 tgatcgccca gaataaggca acagatgata ttgttcatgg tctgaataag gcggttgccg
     4261 taaaaaccgc agctcttacc agacgtgtgg gcggtgagga gaaatatatg atgaccggtg
     4321 gtgtttctaa gaataagggc ctggtaaaga cactggaaga gaagctagga acaaagctgg
     4381 tgatcagtga caaggctcag ctttgcggtg cacttggcgc agcactgttt gcggctgata
     4441 tggctgatgc gtaaattttt atactttttt tataaaagtt taattttcta ttgacgagtt
     4501 caaattta
//
