LOCUS       gnlProkkaEOPLJNPH_52   11370 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EOPLJNPH_52.
ACCESSION   gnlProkkaEOPLJNPH_52
VERSION     gnlProkkaEOPLJNPH_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:34:07
            Original ID  :: gnl|Prokka|EOPLJNPH_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11370
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11370
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2:1370]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..1370
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11370
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11370
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             3..1370
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6.3e-33,
                     bitscore: 103.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.5e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.8e-20, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIE
                     NELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNL
                     ACRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKE
                     VVEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPT
                     RNGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPV
                     VGQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLS
                     GCGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCK
                     DCFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             1371..3146
                     /locus_tag="ctg52_2"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAEDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEVFLEIAAMATVCDVMPLCDENRIIVKEGLRRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHANDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDGFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             3317..4162
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 175.4; E-value: 2.8e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_3"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     EIYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGKIEDLAVTCSLGNNLEINGATCNKGDAMLNLGKILDIP
                     IESIMACGDGNNDFEMVKMAGVGVAMKNGEESLKEVADFVTKTNDEEGVAYAIEHFCNV
                     "
     CDS             4265..4822
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MPDLGAERVDKVKKLEDYVINIPDFPKPGIIFRDITSILRDPEGL
                     KLSVHELMHCLEGTEFDVVVGAESRGFLFGMPLAYNKSKGFVPVRKKGKLPRETVSKEY
                     ALEYGTAEIEIHKEDIRPGQRIVFVDDLLATGGTAKAAIDLIEELGGVVVKVLFVMELE
                     GLHGRDVLKGYDVESVITYPGK"
     CDS             4969..5889
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MEYYEIYLILQNRWKNRVEHLNLLQRIEKKSSEFSKGQRRLAQYI
                     TENYDIAAYLTASKLGKEAGVSESTVVRFAYQLDYEGYPELQKAIQVIVKTNSNSIQRM
                     SLSSKRYQEKGVLKSILYTDAERLRDTIQSGVDEEEFNRSVMLINDARRLYILGARSAA
                     YLAGLMGYYFKMMFDNVIIVDANSTSETLEQIYDISDKDVMMGITFPRYSKRTICALQY
                     AKNHGAKTIALTDNMQSPIVEYADCKLIAKSDVMTIVDSLVCPLSVVNAMVTAIALLRK
                     DDVEKRLMALEELWNEYDVYNRSLL"
     CDS             5889..7130
                     /locus_tag="ctg52_6"
                     /transl_table=11
                     /translation="MNKVIIVGGGAAGMMAAISASKEGKKACILEKNEKLGKKLFITGK
                     GRCNITNACPADEFLTHVVTNPRFLYSTFSQFNNEDMMDYLEEICLPIKTERGQRVFPQ
                     SDRSSDVIDALKKQCKKGGVQIYYHTEVKELLFDEEKENCVGVLLSDGKKMMGDSVILA
                     CGGFSYASTGSNGSGYTLAKQAGHKIKSIEPSLVPFEMKEMWCKDLMGLTLKNIGVRIK
                     AKKKTVYEGFGEFLFTHFGVSGPLVLTASTCLGKYQKELEAGELKLILDLKASLTPEQL
                     DKRFLREFDTYRNKNISNVMERLLPKKMIPVFLEEAQIPEHKKIRDISKKERRHMIELM
                     KNFEMHITGVRGFNEAIVTRGGVNVKEINPSTMESKKVKHLFFAGEMMDLDAVTGGYNL
                     QIAWTTGYVAGKNA"
     CDS             7266..7931
                     /locus_tag="ctg52_7"
                     /transl_table=11
                     /translation="MYSIAIDGPAGAGKSTIAKAIAEDIGFIYVDTGAMYRAIALYFLR
                     KGIDGHDRKLVAAECPNIHVTLEYDEEGKQQVILNGENVTGYIRKEEVGKMASVTSAVP
                     EVRAALLDLQRDMAKTSDILMDGRDIGTNVLPDASLKIYLTASADVRAKRRYDELKEKG
                     ADCDIEQIKTDIIARDKQDMEREIAPLCQAEDAILVDSSDMSIPQVIDTIISEFKKIK"
     CDS             7949..9832
                     /locus_tag="ctg52_8"
                     /transl_table=11
                     /translation="MKINIAKSAGFCFGVKRAVDTVYKESSKKNVYTFGPIIHNDEVVA
                     DLERQGVHVINDSEDFKSLSEGTIIIRSHGVSKAIYDEILNAGLDLVDATCPFVRKIHK
                     IVERESGDGRVIIIIGNNHHPEVEGIMGWCHTHPIVIENREQAEGIELDADTKISIVSQ
                     TTFNYNKFQDLVEIISEKGYDINVFNTICNATEERQTEVRELAKKSDAMIVIGGRHSSN
                     TQKLFEISKKECSNTFYIQTKNDLNMEDFSNIGMLGITAGASTPNNIIKEVHESMAEMS
                     FDQMLEESFKTIRNGEVVQGTIIDVKEDEIILNIGYKADGIISRNEYSNDQNLDLTTVA
                     KVGDEMEAKVLKVNDGEGQVLLTYKRLKAEKGNKRLEEAFNNHEVLKAPVAKVLDGGLS
                     VVVEETRVFIPASLVSDTYEKNLKKYDGQEIEFVITEFNPRKRRIIGDRKQLLVAEKKA
                     KQEALFAKIEAGMTVEGTVKNVTDFGAFIDLGGADGLLHISEMSWGRVENPKKVFTVGE
                     KLNVLIKDIQGEKIALSLKFPETNPWLHADEKYAVGNEVTGKVARMTDFGAFVELEPGV
                     DALLHVSQIAKEHIEKPSDVLKVGQEVTAKVVDFKKDDRKISLSIKALDNE"
     CDS             complement(10368..10874)
                     /locus_tag="ctg52_9"
                     /transl_table=11
                     /translation="MNLEQYTKINNFFIRHSTAFSLLLTANRLLTACGFLLYPLLLLCL
                     LTKKNIAMLISFIAIPALCFLAVTIFRKVVNKKRPYEKLPIQSLIKKDKKGQSFPSRHV
                     FSIFLIATLWFCFWKPVGIFLFIAGVFLAIVRVIGGVHFVTDVCAGALLGVLAGLISNY
                     VFLIC"
     CDS             11053..11370
                     /locus_tag="ctg52_10"
                     /transl_table=11
                     /translation="MGKNIPKERKEGMYKAILELKSLEECFDFFEDICAMTELRSMEQR
                     FEVASMLKKEKVYTEIMSETNASSATISRVNRMLNYGTGCLGEVIDRLNQKEGSEEAKE
                     S"
ORIGIN
        1 ttaacgtgat tcaccagtat aaaaataatg gatataatat tgtcatggat gtgtgcagtg
       61 gtgccattca tgttgttgat gatgtaactt atgatgtcat tgctttatat gaagaaaaaa
      121 gcttagaaga aatagaaaat gaactttctt acagcaagga agatattgag gaagcatata
      181 aagaggtaac ttctttaaaa gaagagggac ttttatttac agaagatatt tacgaagatt
      241 atattaaaga ggtaaagagc agaaagacag tagtaaaggc actttgcctg catattgcgc
      301 atgattgtaa tcttgcctgc cgctattgtt ttgcagaaga aggagagtat aaaggacacc
      361 gtgaacttat gagtgcaaag gttggaaagg ctgcccttga tttccttgta gccaattctg
      421 gaaaccgtca taatcttgaa gttgacttct ttggcggtga gccaacaatg aacttcggtg
      481 ttgtaaagga agttgtagaa tatggacgtt ctcttgaaga aaaacataac aaacatttcc
      541 gtttcacttt gacaaccaat ggtgtgctgt taaatgacga gattatggaa tttgccaata
      601 aagaaatgga caacgttgtt ttaagtgtcg atggacgtaa agaaatccat gattacatgc
      661 gtcctacaag aaatggtaag ccaagctatg accttatcat gccgaagttt atccgttttg
      721 cagagtccag acatcagcag aaatactatg taagaggaac atttaccaat agaaatcttg
      781 atttttccaa agatgttctt catcttgcag acttaggatt tgaacagatt tccatggaac
      841 cagttgttgg acagccagaa gagccgtacg caattcagga aaaagacctt ccacagattt
      901 ttgatgagta tgacagactt gcaaaagaaa tgattaagag agaaaaagca ggaaaaggct
      961 ttaatttctt ccactttatg attgacctta caggtggtcc atgtgtagca aaaagacttt
     1021 ccggctgtgg aagcggaaca gagtatttag cagtaacacc atggggagat ttatatcctt
     1081 gtcaccagtt tgtaggagaa gagaaattcc ttcttggtaa cgtttttgat ggaatcaagc
     1141 gtaccgatat ttgtgacgaa ttccgttcct gcaacgtata cacaaagaaa aaatgtaaag
     1201 actgttttgc gagattctac tgtagcggcg gctgtcctgc aaactcttat aatttccatg
     1261 gaacaattga tgattcttat gatttaagtt gcgatatgga gcgtaagaga gtagaatgcg
     1321 caattatgat taaggctgca ttagcagata cagaaggcga agaagaatag atggaaaagt
     1381 ggtttatcgc ttcaaaaaga gcagatttta ataaaattgg tgagatattt catatcagcc
     1441 cggtaacggc gcgtctgatg agaaatagga gcttaacaac agttagggaa atgcagcgtt
     1501 atctttatgg ttctctgtct gatttatatg attctcatct tttgaaagat gccgataagg
     1561 gagcggaaat cataaaagag aagatagaaa caggcaaaaa gattcggatt atttcggatt
     1621 atgatgtaga tggtgtttcg tcaaactata ttttatatca gggattaaaa cgctgtggtg
     1681 cggatgttga ttataagatt cctgaccgtg tggaagacgg ttatggaatt aatgaacatc
     1741 tgatagaaaa ggcagcagag gacggaattg atacgattat cacctgtgac aatggaattg
     1801 cggcagcaga acagattgct tatggaaatt ctttaggact caccctgatt gtgacagatc
     1861 atcatgatat tccgtttcaa aggcaagaag atggaagcat ttcttataat ttgccgtcag
     1921 ccgctgccgt tattaatccg aagcaaaaag attgtccgta tccatttgaa aatatatgcg
     1981 gagcggttgt tgtctacaag tttattcagg tgctttatga tttgtttgga attgaccgta
     2041 gagaaagtga agtatttctt gagattgcgg cgatggcaac agtctgtgac gttatgccat
     2101 tgtgtgatga gaaccgtatt atcgtaaagg aaggcctgcg acggatacag catacgaata
     2161 ttaccgggct gcaagcttta attgaggcaa atcatcttga agaaaaaaag atatcttctt
     2221 atcactttgg atttattctc ggtccgtgta ttaatgcttc cggtcgtttg acctctgcaa
     2281 aagatgcgtt agaacttctt ctatgcgaag ataaagaact ttgcaggcag aaagcagaag
     2341 cactcacaca gctaaatgca gagcgaaaag aaatgacagc taacggggta aaagctgcaa
     2401 aagaatatct cgaaagcacg ggacatgcaa acgataaggt acttgttgta tatcttccaa
     2461 actgtcacga aagtatcgcc ggaattattg ccggaagaat gaaagaacat taccataagc
     2521 cagtatttgt catcacaaga acaaaagaag gattaaaagg ctctggccgt tctatcgaag
     2581 cctatcatat gtataaggaa atgaacaaaa tcaaggaatg tttcgataaa ttcggtgggc
     2641 acccgatggc agcaggattt tctatgcagg aagaccgctt agaagaattc cgggaaaaat
     2701 taaatgccaa cgcaaccctt accgaagatg atttcgcaga aaaagttcac attgatgtag
     2761 ccttgccgat atcttattta tccgaaagtc tcatcaatga atttgaatta ctagaaccat
     2821 ttggaaatga aaacacaaaa ccgctctttg cacaaaaaga cctttacata aaaggaatgc
     2881 gggtactcgg aacaacaggc agatgtttaa aactcttcct gtcggatgcc aatggaacaa
     2941 gcatagatgc catgtatttt ggagaatccg atggattttt agaagaactc atctcttttt
     3001 gtggaaaaga agaggcacag agaattcaaa aaggcctgtc acatcatata tggatggatg
     3061 tgacttatta tccacaggta aatgaatggc gagggcagaa gaatatccaa atcgtcatcc
     3121 agaattatcg ttttaaaaat ttatgagata aattttttag tgcttctttc gcatattttt
     3181 tcgtctgttt agattcccaa ttaataaaaa actatcctaa tttgacaaat aaggcgagaa
     3241 tcaatagaat aatatgagga tgaaaagaga gatacatcaa aatcgctatg aattaagaga
     3301 tagataagga gaaaatatgg aacaggagaa aaaacagcca gatgtcagat tgataggatt
     3361 agatttagat ggaacaacgc tcacttcaga taaggtgtta actccacata caaaggaagt
     3421 acttgagaaa tgtcttgcgg aagggattca ggttttaccg gcaacaggaa gagtaaaatc
     3481 gggtattcca gagtatttaa cacagattga agggatgaga tatgttattt tatccaatgg
     3541 tgcaagtgta ttagatttaa aagaggataa agttctttat cagaattgta ttccgtggga
     3601 gagagcattg gagttattcg atgtgttaga aatatatgat acattttatg atatttatgc
     3661 attaggagct ggctggtgtg aggctcgctt ttatgataat gtagaaaact atggaattga
     3721 gaaacatatc gagaagctag ttcgtacatc acgcaatcgt attgatgatt taagagagtg
     3781 gatgaaagaa aataaagctc cagtggagaa gataaatatg ttctttgcaa aggaagaaga
     3841 cagacagaga gctttccgtg aacttggaaa gatagaagat ttggcggtta cctgttctct
     3901 tggtaataat cttgagatta atggggcaac ttgtaataaa ggagatgcga tgctcaatct
     3961 tggaaaaatt cttgatattc cgatagaaag tattatggcg tgcggcgatg gcaataacga
     4021 ttttgagatg gttaagatgg ctggtgtcgg tgttgctatg aaaaacggag aagagtcttt
     4081 gaaagaggtt gcagattttg tgacaaagac aaatgatgag gagggcgtag catatgctat
     4141 cgagcatttt tgtaatgtgt aagtagaaat aaacgttttt ctgttgtttt ttacataaaa
     4201 aatctgttat aattaatcat aagaagaaaa agcgcgaaga taaaagtctg tgcttaatag
     4261 ttttatgcct gatttggggg cagaaagggt ggacaaagtg aaaaaacttg aagattatgt
     4321 cattaatatt ccagatttcc caaagccggg aattattttc agagatatta cctctatttt
     4381 acgtgatccg gagggactga aacttagcgt acatgaattg atgcattgct tagagggaac
     4441 agagtttgac gtagttgttg gagcggaatc ccgtggattt ttatttggta tgcctcttgc
     4501 ttacaataaa agcaagggat ttgttcctgt ccgtaagaaa ggaaagctgc caagagagac
     4561 tgtaagcaaa gaatatgctt tagagtatgg aacagcagag attgaaatcc ataaagagga
     4621 cattcgtcca ggacaaagaa tcgtatttgt ggatgacctt ttagcaactg gtggaacagc
     4681 aaaggctgcg attgatttaa tcgaagaact tggtggcgtt gtcgtaaagg ttctgtttgt
     4741 tatggaactt gagggattgc atggccgtga tgtattaaaa ggctatgatg tagagtctgt
     4801 tattacttat cctggaaagt aattttgaag gaaaagaaac tgtgcggatg gaattttttg
     4861 gaagcacagt ttctctttgt gtaaaaattg ttctgtagtt ataaagttga atttctattt
     4921 gcaatttctt cctttaaatc ctgcattttg ctttacaaaa agaagaaaat ggagtattat
     4981 gaaatatact taattttaca gaataggtgg aagaatagag tggaacattt aaatttatta
     5041 cagagaatag agaagaagtc ttccgagttc agtaaaggac agagaagact ggctcagtat
     5101 attacagaga actatgatat tgcggcgtat cttaccgctt caaagcttgg aaaggaagca
     5161 ggagtcagtg agtctacagt ggttcgtttt gcttatcagc ttgattacga gggatatcca
     5221 gagttgcaga aggcaattca ggttattgta aagacaaact caaactccat tcagagaatg
     5281 tccctttcct caaaaagata tcaggaaaaa ggtgtattaa agagtatttt gtatacagat
     5341 gcagagcggc ttcgcgatac gattcagagc ggtgtagatg aggaagaatt taacagatcc
     5401 gttatgctta tcaatgacgc aagaagatta tatattttag gtgcgagaag tgcagcctat
     5461 cttgccggtc tgatgggata ttattttaag atgatgtttg acaatgtaat tatcgtagat
     5521 gccaacagca cgtccgagac attagagcag atttacgata tcagtgataa ggatgttatg
     5581 atgggaatta cttttccaag atattcaaag agaaccatct gtgcgcttca gtatgcgaag
     5641 aatcatggag cgaagacaat cgcacttacc gacaatatgc agtctccaat tgtagagtat
     5701 gcagattgta aattaattgc aaagagtgat gtaatgacaa tcgtggattc tttagtatgt
     5761 ccgttaagtg tggtgaatgc gatggttaca gcgattgcat tgcttcgtaa ggatgatgta
     5821 gagaagcgtc ttatggcact tgaagaactc tggaacgagt atgatgttta taacaggagt
     5881 ttactataat gaacaaagta attattgtag gcggaggggc agccggtatg atggctgcca
     5941 tttctgcgtc taaagagggg aaaaaggcct gcattcttga aaagaacgaa aaacttggca
     6001 agaagctttt tattacgggg aaaggcagat gcaatattac aaatgcctgc ccggcagacg
     6061 aatttcttac ccatgtggta acaaatccaa gatttttata cagtacattt tcgcagttta
     6121 ataatgagga tatgatggac tatttagaag aaatctgtct tccgataaag acagagagag
     6181 gacagagagt atttccacag tccgaccggt cttcggatgt aattgatgca ttaaagaaac
     6241 agtgtaaaaa aggcggggta cagatttact atcacacaga agtaaaagaa ctactttttg
     6301 atgaagaaaa agaaaactgt gtcggtgtac ttttgtctga cggaaagaaa atgatgggag
     6361 attctgttat ccttgcctgc ggcggctttt cctacgcttc taccggttcc aatggatcgg
     6421 gatatacact tgcaaagcag gcaggacata agattaagtc tatagaacca tctttagttc
     6481 catttgagat gaaagaaatg tggtgcaaag atttgatggg acttacttta aagaatatag
     6541 gggtgcgtat caaagcaaag aaaaagacag tttatgaagg atttggagaa tttctcttta
     6601 cgcattttgg agtgagtggt ccgcttgttc ttacggcaag tacctgtctt ggcaaatatc
     6661 agaaagagtt agaggcaggc gaattaaaac tgattcttga tttaaaagcc tctcttaccc
     6721 cggaacagtt agataaacgg tttttaagag aatttgacac ttatcgtaat aaaaatattt
     6781 ctaatgtgat ggaacgtctt cttccaaaga aaatgattcc tgttttctta gaagaagcac
     6841 agattccgga acataaaaag ataagagaca tcagcaaaaa agaaagaagg catatgattg
     6901 agctgatgaa gaatttcgag atgcatatca caggagtccg tggctttaat gaggcaatcg
     6961 tcacgagagg cggagtaaat gtaaaagaaa ttaatccgtc tacaatggag tctaaaaaag
     7021 taaaacattt attttttgcc ggagaaatga tggatttaga tgctgtcaca ggcggctata
     7081 acctgcagat tgcatggaca acaggctacg tagcaggtaa aaatgcgtaa agaaaacgta
     7141 aaatttaaaa aattataaaa aaatagtttt ttttttcgga aaaatatgtt acactaatca
     7201 agtgtaggta aaagtgaaat cactgtatac gcagtcaggt ttcaaaagaa tgggaggaaa
     7261 tgtccatgta cagtatagca attgatgggc cagcaggagc tggaaagagc acgattgcaa
     7321 aggcaatcgc agaagatata ggttttatat atgtagatac cggagcaatg taccgggcaa
     7381 tcgctttata ttttttgcgt aaaggtattg atggacatga caggaagctc gttgcggcag
     7441 aatgtcctaa cattcatgta actttagaat atgacgagga aggaaaacag caggttatct
     7501 taaatggtga gaatgttacc ggatatatcc gtaaggaaga agtcggtaag atggcatcag
     7561 tgacatccgc tgttccagaa gtaagagctg cactgcttga tctgcagcgc gatatggcga
     7621 agacttcgga tatcctcatg gatggaagag acattggaac gaatgtcctg ccagatgcat
     7681 ctcttaagat ttatctgacg gcctctgctg atgtaagagc gaagagacgt tatgacgaat
     7741 tgaaagagaa aggtgcagac tgtgatatcg agcagattaa gaccgatatt atagcaagag
     7801 ataagcagga tatggagaga gagatcgctc cattatgcca ggcagaagat gccatactgg
     7861 tagattcttc tgatatgtca attccgcagg tgattgatac gattatctcc gaatttaaaa
     7921 aaataaaata atattgccgg agtaaatgat gaaaattaac atagcaaaat ctgctggctt
     7981 ttgttttgga gtaaagagag ctgtagatac cgtgtataaa gaatcttcta agaagaatgt
     8041 ttatacattc gggccgatca ttcacaatga tgaagttgtc gcagatctgg aaagacaagg
     8101 ggttcatgtc atcaatgaca gtgaagattt caagtctctt tcagagggaa cgattattat
     8161 tcgttctcac ggcgtgtcaa aagcaattta tgatgagatc cttaatgcgg gtcttgattt
     8221 agtggatgcg acctgccctt ttgtgagaaa gattcataaa atcgtcgagc gggagagtgg
     8281 ggatggcaga gtaatcatta ttataggcaa taaccatcat cctgaagtag aagggattat
     8341 gggttggtgc catacgcatc cgattgtaat tgaaaatcga gagcaggcag aaggaattga
     8401 gttagatgct gatacgaaga tatctatcgt gtcccagacg acatttaact acaataagtt
     8461 tcaagattta gttgaaatta tctcagaaaa gggttatgat ataaatgttt ttaacacgat
     8521 ttgtaatgcg actgaggagc gtcagacgga agtcagggaa ctggcgaaga agtccgatgc
     8581 gatgatagta atcggtggca gacacagttc gaatactcaa aaactttttg agataagtaa
     8641 aaaagaatgt agtaatactt tttatataca aacaaaaaat gatttgaata tggaggattt
     8701 ttctaatatc gggatgctcg gtattactgc aggggcttca accccaaata atattatcaa
     8761 ggaggttcat gaaagcatgg cagaaatgag ttttgaccag atgctggaag aaagttttaa
     8821 gacaatcaga aatggagagg tagttcaggg tactattatc gatgtaaaag aggatgaaat
     8881 catcttaaat attggatata aagccgacgg tatcatttca agaaacgaat attccaacga
     8941 ccagaattta gacttaacaa cagttgctaa agttggtgac gagatggaag ctaaagttct
     9001 taaagtgaat gatggcgaag gacaggttct cttaacatat aagagactta aagcagaaaa
     9061 aggtaataag agattagagg aagcatttaa caaccacgaa gtattaaaag ctcctgtagc
     9121 taaagttctt gatggtggtt taagtgttgt agtggaagaa acaagagtat tcatccctgc
     9181 aagccttgta tccgatactt acgagaagaa cttaaagaaa tatgacggac aggaaatcga
     9241 gttcgttatt acagagttca accctcgcaa gagaagaatc atcggtgacc gtaagcagct
     9301 tttagtagca gagaagaaag caaaacagga agcactgttt gcaaaaatcg aagctggtat
     9361 gactgtagaa ggaactgtaa agaacgtaac agattttggt gcattcatcg atttaggtgg
     9421 agcagacgga cttcttcaca tctctgaaat gagctgggga cgtgttgaga atcctaagaa
     9481 agttttcaca gtaggtgaaa aattaaacgt tcttatcaaa gatatccagg gagaaaagat
     9541 tgcattatcc ttaaaattcc ctgaaacaaa cccatggctt cacgctgacg aaaaatacgc
     9601 agtaggtaac gaagtaactg gtaaagttgc tcgtatgaca gacttcggtg cattcgttga
     9661 attagagcca ggcgtagatg cattacttca tgtttctcag attgctaaag agcacatcga
     9721 gaaaccatct gatgtattaa aagtaggtca ggaagttaca gctaaagttg tagatttcaa
     9781 gaaagatgat cgtaagatca gcttaagcat caaagcttta gataacgaat aatatttagc
     9841 ggaatttggc taggtagacg aaaataaaaa agacttataa tagcacctgt gactttagtc
     9901 gcggcgtgtt gaatgttcgc ttaagggctc gcatccaaca cttgctccga ggtcacatct
     9961 gctattataa gtctttttca ttttctgact ttggcgcaaa ttccgctgtg gaggatttga
    10021 ggattctcca gaagaggatg ggagtgggtg gaaaattttc ttcgttatag ttaatgtttc
    10081 actggcattt tatataattt tgctataaat aaaacttctt ataagtataa tatatattat
    10141 gtgaaaattt atatagaaag catttttaag tccacattta aaaaagcagg aattagattt
    10201 ctgcaattct cactttaatt tatcaaaaaa cagaaaaaag cccctattaa tcctcccaga
    10261 tgtgacctcg gagcaagtgt tggatgcgag ccttttagcg aacattcaac acgtagcgac
    10321 taaagtcaca tctgggagga ttaatagggg cttttttcgt ctgtttttta gcaaatcaaa
    10381 aagacatagt tggaaatcaa tcctgccagc accccgagga gtgccccggc gcatacatca
    10441 gttacgaaat gtaccccgcc aattactctg acaatcgcaa gaaagacacc agcaataaaa
    10501 agaaagattc caacaggttt ccaaaagcaa aaccataatg tagcgattaa aaagatagaa
    10561 aacacatggc ggcttggaaa agactggcct tttttatctt ttttaattag ggattgaatt
    10621 ggaagttttt catatggacg ctttttattc actacttttc taaaaatggt tactgccagg
    10681 aaacagagtg ctgggatagc gataaaacta ataagcatag caatgttctt ttttgttaaa
    10741 agacatagta ataataatgg ataaaggaga aaaccacagg cagtcaataa tcgatttgcc
    10801 gtgagtaata atgaaaaagc agtggagtgt ctgatgaaaa aattattgat ttttgtatac
    10861 tgttctaaat tcataaataa acctcattat caaaaagata gattaagtat agcataaaaa
    10921 gcgagtcaag ggaattatta tagtgttttt gttgtttaaa ggaaaatctc tttaacacat
    10981 taaacttttt atttacgaaa tcaaaaaaag atggtatcat aagattatat ttcgtaaagg
    11041 aaggaacatc ttatgggaaa aaatattcca aaagaacgta aagaaggcat gtataaggct
    11101 attctggagt taaaaagttt agaagaatgt tttgattttt ttgaagacat ttgtgcaatg
    11161 actgaacttc ggtctatgga gcagcgcttt gaggttgcaa gtatgttgaa gaaggaaaaa
    11221 gtttatacgg agattatgag tgagacaaac gcaagttctg ctacaattag tcgtgtaaat
    11281 cgtatgctta attatggaac aggctgtctt ggagaggtaa ttgacagact gaaccaaaaa
    11341 gagggaagcg aagaggctaa agaatcttag
//
