LOCUS       c00011_gnlPro..        14321 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EOPLJNPH_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:54:34
            Original ID  :: gnl|Prokka|EOPLJNPH_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 24478
            Orig. end    :: 38799
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14321
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[34478:38717](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14239
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14321
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14321
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2020..3729)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_25"
                     /sec_met_domain="Dak2 (E-value: 3.4e-40, bitscore: 128.9,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNSHTIDAKTFQKLFLAGANRINSRKDYINELNVFPVPDGDTGTN
                     MSLTILAAAKEVGAVAEPTMATICKAISNGSLRGARGNSGVILSQLFRGFTKAVSKADS
                     LGKDEITAGFTRAVETAYKAVMKPKEGTILTVAKGMADKAEELVDEDMDVIAFCEAIVA
                     YGYEVLSKTPDMLPVLKEAGVVDSGGQGLMEVLQGIVDALTGKVTDIEVPAEAASMSSA
                     VISAPKADISTADIKFGYCTEFIILLDKPLTKEDEKGLKKFFLSIGDSLVLVADEEICK
                     VHVHTNHPGEAFEKALTFGALSNMKIDNMRLEHQEKLIKDAENEAARQRQQEAEEEELA
                     AKEAAAEKPAKEVGFIAVSVGEGLTDIFKGLGVDYLIEGGQTMNPSTEDMLNAIEQVNA
                     KNIFILPNNKNIILAAEQARDLIEDKKIIVLPTKTIPQGISAMIGYMPEAGVDENEENM
                     KEAYQDIASGQVTYAVRDTVIDGKEIHNGDIMGINDDGIAAVGKNLTETTLELLSTMAD
                     EDSELICLYYGADVTKDDADTLSDAIEDKFPECEVEVNFGGQPIYYYMISVE"
     CDS             complement(3898..4254)
                     /locus_tag="ctg11_26"
                     /transl_table=11
                     /translation="MKGQMHTDLGQVIIDEEVIATYAGINAIECFGIVGMASVNMKDGF
                     AQLLKRDNVSKGVHIKINDNKIYIDFHIIVVYGVSIATVTENLIQNVKYRVEKFTGMSV
                     EKINIYVEGVRIVD"
     CDS             complement(5095..5535)
                     /locus_tag="ctg11_27"
                     /transl_table=11
                     /translation="MDKQNFDTTVNSLFSGMDHVLSSKTVVGEPQVIGDTIILPLVDIS
                     FGMGAGAFNKEKGSSAGGGIGGKMSPSAILVIHNGQTKLVNIRDQDAVTKVLDMVPDAV
                     NKVVSIIKGEDAEDKVDPEVESAVNKAAQAEASVVDVDGAGI"
     CDS             complement(5551..6666)
                     /locus_tag="ctg11_28"
                     /transl_table=11
                     /translation="VLYVLLLLLKILGILLLLLIGLVLLVLLTPIRYSFELEKEEQKEP
                     KFMVRVTWLFWLFYFKTSYIEKVFNYRIRILGYQIAGNQPEFLEKQKERQKKKSQKEKA
                     KEERKKNKEDREKQQEEKSGKPNKKKNPEESVKDTQAAVTEKELPVKKEPEEDILRSNA
                     SADIPQSMSAETLAEGKSRSIDSVSKQKAEKAAPKEKSLDVSEGREKTKEKDSGDDKNS
                     KDKKKNKEKKQKDGKKPKKESSLKKIKSKIKSLKETKVNLDKMPWREWLELGKDVLIRF
                     LKHVLPGKIEGNIAFGTGNPEYTGYITGIAAVFYPKYGEYFSLYPDFERKLFEAKCRGR
                     GRIRLGYMLVLAVSILKEKSVRTMIKNIILG"
     CDS             complement(6682..6858)
                     /locus_tag="ctg11_29"
                     /transl_table=11
                     /translation="MYILSSREMRQKFYQNNDLKLLGLAGSMKEAYEIVLKLVQMGYNN
                     DCIYEMNDYLEKF"
     CDS             complement(7108..7923)
                     /locus_tag="ctg11_30"
                     /transl_table=11
                     /translation="MNWLDKLERKFGRYAIRNLPLYIVMLYAIGAVLNILTKGSYYYYV
                     ALNPYMILHGQIWRLLGFLIVPPNASLIFIIFVLMFYYSIGESLVQVWGAFRFNMYILI
                     GVLATIVASFIVYFIYPSTMIFMDTFYLNLSMFLAYATIFPEMRVYLYGILPLKVKWMA
                     WFDVALLVWQFVVGGLGARIAIVVSLLNFLLFYFSSRNYKKVSPKEIHRKRAYRKASSV
                     ASNKPYRHKCAVCGKTELDDPNLEFRYCSKCNGNYEYCNEHLFTHTHVK"
     CDS             complement(8070..8960)
                     /locus_tag="ctg11_31"
                     /transl_table=11
                     /translation="VAEEGCWIALTNPTAEELSTTADQFNIDVDDLKSPLDEEERSRIQ
                     VEENYTLIILDIPTIEERKGREYFYTIPFGIIFTDKYIFTVCLVDSPVLTVFMDGRVRD
                     FYTYKRTRFIYQMLYRNATMFLQYLKIIDKKSDEVEKKLHISQRNQELIEMLDLEKSLV
                     YFTTSLRGNEVVLEKLMRNTSIPRYEDDEELLEDVIIENKQAIEMAKIYSDILSGTMDA
                     FASVISNNLNIAMKFLSVITIVLTVPTIVTSALGMNVAGIPFANNPYGFWIVVGISLLL
                     TLIAGAIIAKNKHFK"
     CDS             complement(9204..9575)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_32"
                     /sec_met_domain="LysM (E-value: 3.2e-14, bitscore: 44.0,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKVYVNICDTKKCPGLVYAVKTGDTLYSIAQRHHCRVRTLLDL
                     NPFVDIYNLQPGEEICVPDCRGQGKVDFRPYVVKEGDTLKIILKNVSMTFEELAKVNRI
                     LYNLTVPAGTILLVPAKKE"
     CDS             10001..14239
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_33"
                     /sec_met_domain="HGD-D (E-value: 9.3e-64, bitscore: 207.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.2e-37, bitscore:
                     118.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHALGIDIGSTTVKVTVINESHDILFSDYKRHFANIKGTLQTLL
                     SEAREKLGNLTIHPTVTGSGGMAISEYLHIPFCQEVVCVANALQDYEPKTDVAIELGGE
                     DAKIIYFNNGIEQRMNGVCAGGTGSFIDQMASLLQTDATGLNEYARDYDTLYPIAARCG
                     VFAKSDIQPLINEGATKENLAASIFQAVVNQTISGLACGKPIKGYVAFLGGPLHFMPEL
                     KNAFIRTLNLDEEHIIDPPYSHLFAAKGAALNAKEECSFTLDDLLKEFESDIQLAVEVE
                     RMEPLFKDEKEYDEFIEEHNQFKVKKADLATYSGKCYLGIDAGSTTTKLALVGEDGSLL
                     YRFYDNNNGSPLNTTIRAMKELKELLPPAAKISGSCSTGYGEALIKAALQLDHGEVETM
                     AHYYAAAFFEPDVDCILDIGGQDMKCIKIRNHAVDNVLLNEACSSGCGSFIETFAKSLN
                     YSVADFAKVALFAPSPIDLGSRCTVFMNSKVKQAQKEGASVGDISAGLAYSVIRNALLK
                     VIKLTDPKQLGKKIVVQGGTFYNDAVLRSFERISGCHAVRPDIAGIMGAFGAALIARER
                     EEETGDTQMLSIDEIINLEYSTSMSRCQGCNNHCILTINKFNNDRQFISGNRCERGLGL
                     EKNHEHVPNLYEYKYKRIFGYKALKPDEAKRGVIGIPRVLNMYENYPFWYTFFTNLSFR
                     VLLSPKSSRKIYELGIESIPSESECYPAKIAHGHVMWLLKKGINTIFYPCVPYEEDQME
                     GANNHYNCPIVTSYAENIKNNMEELRDPNVLFMNPFLALDNADALKVRLYDELSKHFDV
                     TKEEIDHAVDEAYKEAAQVRKDVQAKGEETLAYLAETGKMGIVLCGRPYHIDPEINHGI
                     PELINSFGIAVLSEDSICHLGHVERPLIVSDQWMYHSRLYAAANYAKKNKQLEVIQLNS
                     FGCGLDAVTTDQVNDIMTNSGRIYTVLKIDEVNNLGAARIRIRSLIAAVKIRNRKHIEP
                     HPVPANIEKVEFTKEMKKDYTILIPQMSPIHFDLLTPAFRHCGYNVEILPEMGKQAVDT
                     GLKYVNNDACYPSLIVVGQIMTALTSGKYDLNKTAVIISQTGGGCRATNYIGFIRRALA
                     KNGYGQIPVISLSVQGIEKNEGFKFTPALLVRALQGVIYGDLFMRVLYRVRPYEKVKGS
                     ANHLHEVWKKRCIKSLEKARYGEFKKNIRGIIRDFDRLPITDEKKPRVGIVGEILVKFL
                     PDANNHLVELLEEEGAEAVMPDLLDFMFYSFYNSNFKAEYLGKSTKAAKLCNMAISALE
                     AYRGFLRKELERSDRFTAPPHIEELAEYAKPIVSLGNQTGEGWFLTGEMVELIKQGAPN
                     IVCTQPFACLPNHVVGKGVIKELRRKYPESNIVAIDYDPGASEVNQVNRIKLMLATAEK
                     KLKSDLPQAR"
ORIGIN
        1 tacaccaaaa aactctcccg gaccacgaag ttttaaatct tcattggcaa tctcaaatcc
       61 atcattagaa tgtccgataa tggaaagacg ttccatcgct tcttcttttt ctgaaccaga
      121 aataaagaca cagtatgact gtgcttttcc tcttccaaca cgtccgcgga gctgatggag
      181 ctgagcaagg ccaaaccgtt ccgcattctc tatgagcata acggttgcat ttggaacatc
      241 aataccgact tctacaacgg tagtagaaac taaaatctga atttcattct tcgaaaagcg
      301 ttccataata tcattctttt ctgccgggcg catatgtcca tttaaagctt caacggtaat
      361 agaaggcggt aatgcctgcg aaagcattct tgcatactct tccacatttt ccaaatccat
      421 tttttcattt tcctcaatca tcggacagat cacatatgcc tgatgtccaa gtgctacctg
      481 ctttcttata aattcccatg cagccggacg ataggaagtt cccacaacag aatttttaat
      541 cggcagtctg gaagccggca tttcattcat aatgctaaca tctaaatctc tgtacaaaat
      601 aattcccagt gtacgtggaa tcggcgtcgc actcattaca agaacatggg ggtctttccc
      661 ttttttcata aaggcatctc tttgttttac tccaaaacga tgctgctcat cggtaacaat
      721 aaatgcaaga ttgtcaaaag ctacatcgtc ctgtatcact gcatgcgttc caattaaaat
      781 ttgaatctca ccagaggcac aggctgcctt tatctctctt ttttcctttg cttttgtgga
      841 accggtaagc agggcaacgg taatcccaag tggggaaagg agtttcacaa agttctggta
      901 atgctgttct gcaagtacct ctgtcggagc catcaacgcc gcttggtaac cggcaagaac
      961 agcagcatac atcgctgtca ttgctacaat cgtctttccc gaaccaacgt ctccctgtaa
     1021 aaggcggttc attgccattg tatcggaaaa gtcctggcga atttcattta acaccttttt
     1081 ttgtgcccct gtaagaggat acggtaaatt ttctacaaac ctctttacgg gttcttccat
     1141 tggaataata tagtgattga gtgcttgttc ctccctgtct ttgacaagtt ctaacgcact
     1201 gaaaaaacgg aaaaattcat caaaaatgat tcgctttttc gcctccatca aatgttcggt
     1261 ccctgtagga aaatgtactt ctctaagtgc tgtattcact ggttctaaat cataataatt
     1321 tcgaacggtt tccggaagat actcttcttc tctgtacctt tcaaatgcag ctgcctgtgc
     1381 tttttgtact gtcttattcg acaatcctgt tgtgagaggg taaatcggct gaaatgtttc
     1441 cattaactgc aaatattttt ccctcttaca gtactccggc tgttctaaca taagacgtcc
     1501 atctttataa atcggagttc ctgtaaaaat ccaccgttct ccctgtttta atgtatttcg
     1561 aagatatggc atattaaacc agcgcacaaa aagctgtccg ctgacatctg cgataagccc
     1621 ggtacaaagt tttaacttcc gaacagtctt tagatgaatc ggggaagcaa tttctgcctc
     1681 aatcgaacat ctttgtcctg tctttatctc tgatatggaa attggctctg gataagtcgt
     1741 gtagcaacga ggatagtgat gcaccaactg atccacggtc tctatgtcaa gctttgcaag
     1801 taacttttcc gtcttttctc caattccttt aatttccctt actggtattc ccaactgaga
     1861 ttctccttcc tccacatgca tcatgtggta atattatttt atcttaatca aaacactctt
     1921 atatgaaaat agcagcgatt ccatgtcaat acacggaatt gctgccacaa aggagtgatt
     1981 tattccctct tttttcatta tatcattatt tcatttatct tactcgacag aaatcatata
     2041 gtaatagatt ggctgtccgc caaagttgac ctctacttcg cattctggga acttatcctc
     2101 aattgcatcg gaaagtgtat ctgcatcatc tttggttaca tcggctccat agtaaaggca
     2161 aataagttcc gaatcttcat ctgccattgt agaaagtaat tctaatgttg tctcagtaag
     2221 attctttcct actgcagcga ttccatcatc attgattccc atgatgtctc cattatgaat
     2281 ttcctttcca tcaattactg tgtctcgtac cgcgtaagta acctgaccgc ttgcaatatc
     2341 ctgataagcc tctttcatat tctcttcgtt ctcatccaca cctgcttctg gcatatatcc
     2401 aatcattgcg gatattccct gtggaattgt ctttgttgga agaacgataa tcttcttgtc
     2461 ttctattaaa tctctggcct gctctgctgc aagaataata ttcttattat ttggcaggat
     2521 aaagatattc tttgcattga cctgctcgat tgcgttaagc atatcctctg tgctaggatt
     2581 catcgtctgg ccgccttcaa taaggtaatc tacaccaaga cctttgaaaa tatcggtaag
     2641 tccctcacca acagatactg caataaatcc aacttctttg gctggttttt ctgcagctgc
     2701 ttctttagca gcaagttcct cttcttctgc ttcctgctgt ctctgacggg ctgcctcatt
     2761 ctctgcatct ttgatgagct tctcctgatg ctctaagcgc atattgtcaa tcttcatatt
     2821 agaaagcgca ccaaatgtta aggccttttc aaaggcttct cctggatgat ttgtgtgtac
     2881 atgtacttta caaatctctt catccgcaac taatactaaa gaatcaccta tagaaaggaa
     2941 gaacttcttt aatcccttct catcttcttt tgtgagcggc ttatctaaca aaataataaa
     3001 ttctgtacag tagccaaact tgatatctgc tgtagaaata tctgcttttg gtgcactgat
     3061 tactgcagat gacatagacg ctgcctctgc cggaacttca atgtctgtta ccttgccggt
     3121 aagagcatca acaattccct gtaacacttc cataagaccc tgtccgccag aatctactac
     3181 acctgcctct tttaataccg gaagcatatc tggtgtctta gaaaggactt cgtagccgta
     3241 ggcaacgatt gcctcgcaga atgcgataac atccatatcc tcatcgacta actcttctgc
     3301 cttatctgcc attccttttg caaccgtaag gatagttcct tcttttggct tcataactgc
     3361 cttatacgct gtctctactg ctcttgtaaa tccggctgta atctcatcct taccaagaga
     3421 atccgcttta gaaactgcct ttgtgaatcc tcggaatagc tgggaaagga ttacaccaga
     3481 gttaccacgg gctccacgaa gagaaccatt gctgatagct ttacatattg tagccattgt
     3541 aggttcagca actgctccaa cttccttagc tgctgctaaa attgtcaggg acatatttgt
     3601 tccggtatct ccatcgggaa ccggaaatac attcagttcg ttgatataat cttttctgga
     3661 attaatacgg tttgcaccgg ctaaaaacaa tttctgaaaa gtttttgcgt ctatggtgtg
     3721 actgttcaca acatttcctc cttatttacc tgttttatct ataattcata gtagttatct
     3781 tgttctttta ttctataaaa aggaatccct tctaaagcgt tatcttagag cgtgtttgaa
     3841 aaatcattcc agcaacctgc acgccccaat ttgcagaaag catttttcaa acacgttcta
     3901 atctacgata cggactccct ctacataaat attaattttc tctacactca taccggtaaa
     3961 cttctccacg cggtacttta cattctgaat taaattctct gtaactgtag ctatggagac
     4021 accatatact acaataatat gaaaatctat ataaatcttg ttatcattta tcttgatatg
     4081 aacgcccttg cttacattgt ctctctttaa aagctgggca aaaccatctt tcatattcac
     4141 agatgccatt ccaacgatac caaaacactc aatcgcgtta attccggcat aagttgcaat
     4201 aacctcttca tctataataa cctgacctaa atcggtgtgc atttgtccct tcatatacta
     4261 tccctccgtt ttattatcgt tttctatagt ataacctctt ttcggtgaaa ttggaaccac
     4321 aaacataaaa ttcttccatt taagtacttt ctcctgaaac aaaaaaagta tcttcccata
     4381 tactattata aggaacatat tggggagatt ttatgaaaaa attatgcgga ttcgctcttt
     4441 tttgcttttc ctttggtctg ttcctgagct gctttctcac cggctttgca gtaaagttca
     4501 ttattctggt catcagcatc ctgcttggat atctgctgtt ttgtgaccga ttttaacaga
     4561 aaagaaaaaa gagggaatca ctgattccct cttaactcat atctgcatac attcctgtaa
     4621 ggacaaagat tagagtcttc tcttatcctc agtgacagta aaactacgca cgttctactt
     4681 tacctgatct taaacaagaa gtacaaacat acattttctt agaagctccg ttcactttca
     4741 ctcttacaga cttaatgttg gatttccaca ttttgtttga tcttctatgt gaatgactca
     4801 ctttgatacc gaaatgagca cctttgtcac aaatagcgca tcttgccatg atagcacctc
     4861 ctcgcgaata tacttaagtc tgacagactt acaacgagtc tatactatca gaaatcaaaa
     4921 caaattgcaa ggaaaacttt taaaaatctt cacttttttt atttgattga tctaaggcaa
     4981 cccaaagtgt gtttaaaaac cgctttctat acgatatgca ttacacttcg tggaagattt
     5041 ttcctgcacg aaagtaacgt ggtaatctca cgttaactga ataccgaata ccttttaaat
     5101 tcctgcgcca tctacatcta caacagaagc ctctgcctgt gctgctttat tcaccgcaga
     5161 ttctacttcc gggtcaactt tgtcctctgc gtcctctccc ttaataatag aaacaacttt
     5221 atttacggca tctggaacca tatcaagtac tttggtaacg gcatcctgat ctctgatatt
     5281 gacaagcttt gtctgtccgt tatgaataac taaaatagca cttggggaca ttttacctcc
     5341 gattccaccg cctgcactgc ttcccttttc tttattaaag gcacctgctc ccattccaaa
     5401 ggaaatgtca acaagtggca gaataatcgt atctccaata acctgtggtt ctccaacaac
     5461 tgtctttgaa gataatacgt ggtccattcc actaaataaa gaattcactg ttgtatcaaa
     5521 gttttgttta tccattgtac gccctcctgt ttaacctaaa atgatgtttt taatcattgt
     5581 tcttacactt ttctctttta atatagaaac agccagaaca agcatatatc ccagccggat
     5641 tcttcctctt cccctgcact tggcctcgaa cagctttctt tcaaaatccg gatatagaga
     5701 aaaatattct ccatatttcg gataaaaaac agccgcaatt cctgtaatat atcctgtgta
     5761 ttccggatta ccagttccaa atgcaatgtt tccttctatc tttcccggaa gaacatgctt
     5821 tagaaagcga ataagaacgt cctttcccag ctctaaccat tcccgccacg gcattttatc
     5881 taaattaacc tttgtttctt ttaagctttt tattttgctt tttatttttt ttaaagaaga
     5941 ctctttcttt ggtttctttc catctttttg ctttttttct ttattctttt tcttatcttt
     6001 actattttta tcatctccag agtctttctc ttttgttttt tctctgcctt ctgacacatc
     6061 taaggatttc tctttagggg ctgccttttc cgctttctgt ttagaaacag aatctatgct
     6121 tcgacttttt ccctctgcca gtgtctctgc tgacatactt tggggtatat ctgccgatgc
     6181 atttgaccga agaatatctt cctccggttc tttcttcaca ggcagttcct tctctgttac
     6241 cgcagcctgt gtatccttga cagattcttc tggatttttc tttttgttcg gttttcccga
     6301 tttttcttct tgttgctttt ccctgtcttc tttgtttttt ttacgttctt cttttgcttt
     6361 ttccttttga gacttctttt tttgccgttc tttctgtttt tcaagaaatt ccggctgatt
     6421 cccggcaatc tgatacccca gtatacgtat ccggtaatta aagaccttct ctatgtaact
     6481 ggtcttaaaa taaaaaagcc agaacagcca ggtaactctt accataaact ttggttcctt
     6541 ctgttcctcc ttttcgagtt caaaagaata ccgaatcggc gttagcaaaa caagcaaaac
     6601 aagtccgata agtaacagga gcagtattcc aagtattttt aatagtaata ataatacata
     6661 cagcacattt ctcctcctgt tttaaaactt ctccagataa tcattcatct catagataca
     6721 atcattatta tatcccatct gcacaagttt taacacaatt tcataagcct ctttcataga
     6781 acctgcaagt cctaacagct ttaaatcatt gttctgataa aacttctgcc tcatctctct
     6841 tgaagaaagg atatacatga tcgcatcttt ctcacaggaa gtcgtaatac cataccaaag
     6901 tcctttcttc catataaaag gatggcggac tccccgcaat atagccttcg catcgtggga
     6961 aatcgtctcc ccaattatga tgtgttctga tattatcaac aaaagaccgc ctcctatcat
     7021 gatttatttg ctacttatgt tataccttta ttctatccat taatttttca gatttctatg
     7081 aaagaatata actcttttaa tattgcttta ttttacatgc gtatgtgtaa ataaatgttc
     7141 attacaatat tcataatttc cattacactt tgagcagtaa cggaattcta aatttgggtc
     7201 atctaattct gtcttaccac agactgcaca cttatgacga tatggtttat ttgaagccac
     7261 agatgatgcc ttccggtatg ctctctttct gtgaatctct tttggagaaa cctttttata
     7321 attccttgat gagaagtaaa acagcagaaa gttcagtaaa cttactacaa tagcaattct
     7381 tgctccaagt cctccaacga caaactgcca aactaaaagc gccacatcaa accacgccat
     7441 ccactttact ttcagcggaa gaataccata aagatatacc cgcatctccg ggaatatcgt
     7501 ggcgtaggct aaaaacatgg ataagttcaa ataaaaagta tccatgaaaa tcattgttga
     7561 tggataaata aaatatacaa taaatgatgc cacaattgtc gcaagaactc ctataaggat
     7621 atacatatta aagcgaaatg ctccccatac ctgtactaaa gattctccaa tcgaatagta
     7681 aaacatcagt acaaaaataa taaaaatgag acttgcattc ggtggcacaa taaggaaacc
     7741 aagcagtctc caaatctgtc catgaagtat catatacgga tttaatgcga cataatagta
     7801 ataagaacct tttgtcaaaa tattaagtac cgctcctatc gcatacagca taacgatata
     7861 cagcggcaga tttcgtatcg catatcttcc aaatttacgt tccagcttat ctagccaatt
     7921 catggcactc ctcctttaac tttcaatgta ctgacaagaa accttctgca aaaacaagtg
     7981 cagtaaaaat cccaagcgta cattcttaat aaaatatttt tgtttataaa tgaacagccg
     8041 gaaatcccgg ctgtctcata catattcaat tatttaaaat gtttattctt ggcaatgatt
     8101 gctccggcaa tcagagtcag taataaagag attcctacaa caatccaaaa tccatatgga
     8161 ttattcgcaa atggaattcc tgctacgttc ataccaagcg cacttgtaac aatcgttggt
     8221 acagtaagca caatggtaat aactgacaaa aacttcatcg caatatttaa gttattcgat
     8281 ataacagaag caaaggcatc cattgttcca cttaaaatat cactataaat cttcgccatc
     8341 tcaatcgcct gcttattctc gatgataaca tcttcaagta actcctcgtc atcttcataa
     8401 cgtggaatgg atgtattacg catcagtttc tcaagaacaa cctcgttgcc tcgcagagaa
     8461 gttgtaaaat atacaagact cttctctaaa tcaagcattt caatcaattc ctgatttctc
     8521 tgagaaatgt gaagcttctt ctccacttca tcactcttct tgtcaataat cttcagatac
     8581 tgcagaaaca tcgtcgcatt gcggtataac atctggtaga tgaaacgagt tctcttatac
     8641 gtataaaaat ccctcactct tccatccata aatacggtca gtaccggtga gtctacaaga
     8701 cagacggtaa atatatactt atcagtaaag ataattccaa acggtatcgt atagaagtat
     8761 tctcttccct tacgctcttc gattgttgga atatccagga taattaatgt gtaattttcc
     8821 tccacctgta tacgggaacg ttcctcctca tccaaggggc tttttaaatc gtcaacatca
     8881 atgttaaact ggtctgctgt ggtacttagt tcttctgccg taggattggt aagggctatc
     8941 cagcatcctt cctctgccac tgcaactttg cgaatccctg aatcggtcgt tttaaaaatt
     9001 cttatcatga gacttccctc tttcaacagt ttatcgtatc tcagtctgca tcttctctat
     9061 cttggcaaaa cgaaagaaag agtccgtttc gcggactctt acataactga aaccgtttaa
     9121 atttattata agaaatatct aatactttgt caaacgcatt tctgtgattt ttttactatt
     9181 ttttaactgc ttttcttttt catttattct ttttttgcag gaacgagcag aatcgttccc
     9241 gctggtacag taagattata caaaatacgg tttacctttg ctaattcttc aaaggtcatt
     9301 gaaacatttt tcaggataat ttttaatgta tccccttctt ttactacata aggccggaaa
     9361 tctactttcc cctgtcccct gcagtctggt acacagattt cctcacccgg ctgcaaatta
     9421 tatatatcta caaaagggtt tagatcaaga agtgttctta cccggcaatg atgcctttgt
     9481 gcaatgctat acagcgtatc tcctgtcttt actgcataca ccaggccggg gcattttttg
     9541 gtgtcacata tgtttacata aactttttca ctcatagatg ctcttccttt ttcttcctca
     9601 attataaaat atgacagtca gagaaaaagg tactttatcg tgaaaaactc ctcatacaaa
     9661 tactcccctc ttcttttgct ttttgtaaac attttccatt cattatatct ttttttcgaa
     9721 atttgttgta ttttacgttc aactcgttta taatggtttg gatattgaga aatttatcta
     9781 tatatagtga ttcagagcca tagtgtctgt ctcattgcct ttctgtcaaa taacgcagaa
     9841 tgctttttca tcaacaaagt gactgaacaa gacgatacgg tggcatcggc aagcgaagtg
     9901 tatcgcggac ggtgttataa atgtattctg aacattagat taccttattt taatacacaa
     9961 catgaataca cattttacta aaggagatga ttgattaatc atgaaacacg cattaggtat
    10021 tgatattggt tctactaccg ttaaggtaac agttatcaat gagagccatg atatcctttt
    10081 ttccgattac aaacgacatt ttgcaaatat taaaggaact ttacagacct tattatctga
    10141 ggcgagagaa aagctaggca atctcacaat ccatccaacc gtaactggtt ccggtgggat
    10201 ggcaatctca gaatacttac atattccatt ctgtcaggaa gtagtttgtg tggcgaatgc
    10261 cttacaggat tatgaaccaa aaacagacgt agcaatcgaa cttggcggtg aagacgccaa
    10321 gattatttat tttaataacg gaattgagca gcgtatgaac ggtgtatgtg ccggtggtac
    10381 tggttctttc atcgaccaga tggcaagtct tttacagaca gatgcaaccg gtcttaatga
    10441 atatgcccgt gattacgata ccctctatcc aatcgccgct cgttgcggtg ttttcgcaaa
    10501 gtctgatatt cagccattaa tcaatgaggg ggcaacaaaa gaaaatcttg ctgcttctat
    10561 cttccaggct gtagtaaacc agacaatcag tggtcttgcc tgtggtaaac caatcaaggg
    10621 atatgtcgct ttccttggtg gtcctcttca ctttatgcca gaattaaaga atgcatttat
    10681 ccgtacttta aatctggacg aagaacatat tatcgaccct ccatactctc atctttttgc
    10741 agcaaaaggt gccgcattaa acgcaaaaga agaatgttcc ttcacattag atgatctctt
    10801 aaaagagttt gaatccgaca ttcagcttgc tgtagaagta gaacgtatgg agcctctttt
    10861 taaagacgaa aaagaatatg atgaatttat cgaagagcac aaccaattca aggtgaaaaa
    10921 ggcagactta gctacctaca gtggcaaatg ctatctcggt attgatgccg gatctacgac
    10981 aacaaagctt gctttagttg gagaagatgg ttccctctta taccgtttct acgataataa
    11041 taacggaagt ccgttaaata caacaattcg tgctatgaaa gagttaaagg agttacttcc
    11101 tcctgctgcg aagatttccg gttcctgttc tactggttac ggtgaagcat taattaaggc
    11161 tgcactgcag cttgaccacg gcgaagtaga gacaatggca cattactatg ctgccgcttt
    11221 cttcgagcca gatgtagact gtattttaga tatcggcgga caagatatga aatgtatcaa
    11281 gattcgtaac cacgctgtag ataacgtact tttaaatgag gcctgttctt ctggatgtgg
    11341 ttctttcatc gaaactttcg caaaatctct gaactattct gtagctgatt ttgcaaaggt
    11401 tgcgctgttt gccccatctc caatcgactt aggttcccgc tgcactgtat ttatgaactc
    11461 caaggtaaaa caggcacaaa aagaaggcgc aagcgttggt gatatttctg ctggccttgc
    11521 ttattccgtt atccgtaatg ccttattaaa agttattaag ttaaccgacc ccaaacagct
    11581 tggtaaaaaa atcgttgttc agggtggtac attctataat gatgcggtac ttcgaagctt
    11641 tgaacgtatt tccggctgtc acgccgttcg tccagatatt gccggtatca tgggtgcttt
    11701 cggtgcagcc ttaattgcaa gagagcgtga ggaagaaact ggagatacac agatgctctc
    11761 catcgacgag attatcaact tggaatacag cacttccatg agccgctgtc agggatgtaa
    11821 caaccactgt atccttacca ttaataagtt taacaacgac cgtcagttta tttctggtaa
    11881 ccgttgtgaa cgtggtcttg gccttgaaaa gaatcatgag catgtaccaa acctttacga
    11941 atataaatat aaacgaattt ttggatataa agcattaaaa ccagacgagg caaaacgtgg
    12001 tgttatcggt attccacgag tactgaatat gtatgagaac tatccattct ggtatacatt
    12061 ctttacaaac ctttctttcc gggtattgct ttctccaaag tcttcccgaa agatttacga
    12121 gcttggtatt gagtccattc caagtgaatc cgaatgctat cctgcaaaga ttgcacacgg
    12181 acatgtaatg tggcttttaa agaagggtat caacaccatt ttctatcctt gtgttcctta
    12241 tgaggaagat cagatggaag gtgccaacaa ccattacaac tgcccgatcg taacatctta
    12301 tgcagaaaat attaaaaaca acatggaaga gctccgtgat ccgaatgtcc tttttatgaa
    12361 cccattctta gcactcgata atgcagatgc cttgaaggta cgtctttatg acgagttatc
    12421 taaacatttc gatgtgacaa aagaagagat tgaccatgcc gtagatgaag cttataaaga
    12481 agctgcacag gtaagaaaag atgtacaggc aaagggcgaa gaaacacttg cttatctcgc
    12541 agaaactgga aagatgggta ttgttctttg tggtcgccct taccatatcg acccagagat
    12601 taaccacggt attcctgaac tgattaactc ttttggcatc gccgtattaa gtgaagattc
    12661 catctgtcac ttaggtcatg ttgagcgtcc attaatcgtt tctgaccagt ggatgtatca
    12721 ttcccgtctg tacgctgccg caaactacgc aaagaagaac aagcagttag aagtcattca
    12781 gcttaactcc tttggctgtg gtcttgatgc ggtaactacc gaccaggtaa atgatattat
    12841 gacgaattcc ggacgtattt ataccgtcct taagattgat gaggtaaata acttaggtgc
    12901 tgccagaatc cgtatccgtt ctctgattgc tgccgtaaag atcagaaacc gtaagcacat
    12961 tgagccacat ccggttccgg caaatatcga aaaagtagaa tttacaaaag aaatgaaaaa
    13021 ggactacacc attctgattc ctcagatgtc cccaattcat tttgacctgc tcacccctgc
    13081 cttccgtcac tgtggctata acgtagagat tttgccggaa atggggaaac aggcagtaga
    13141 tactggatta aaatatgtaa ataacgatgc ctgctatcca tcccttatcg ttgttggaca
    13201 gattatgact gccttaactt ccggcaaata cgacctgaac aaaacagccg ttatcatctc
    13261 ccagactggt ggtggctgtc gtgcgacaaa ctatatcgga ttcatccgcc gtgcattagc
    13321 taagaacggt tacggtcaga ttccagttat cagtttaagc gtacagggaa ttgagaagaa
    13381 tgaaggtttt aaattcactc cggcactttt agttcgtgcc cttcagggag ttatttacgg
    13441 agatttattt atgcgtgttc tctaccgtgt ccgcccatac gaaaaagtaa aaggttctgc
    13501 aaatcattta catgaagtat ggaaaaagcg ttgtattaaa tctcttgaga aagcacgata
    13561 tggagaattt aagaaaaata tccgcggcat tatccgcgac tttgacagat taccaatcac
    13621 agatgagaag aaacctcgtg ttggtatcgt tggagaaatc ctcgtaaaat tccttccaga
    13681 cgcaaacaac catctggtag aacttttaga agaagagggg gcagaggcag taatgccaga
    13741 tttattagac tttatgttct actccttcta caatagtaat tttaaagcag aatatctcgg
    13801 aaaatctaca aaagctgcta agttatgtaa tatggcaatc tctgcactgg aagcttaccg
    13861 aggcttcctg cgaaaagaat tagaaagaag cgatcgtttc actgcaccac ctcacattga
    13921 ggaacttgcc gagtacgcaa aaccaatcgt atccctcggt aaccagaccg gtgagggatg
    13981 gttcttaact ggtgaaatgg ttgaacttat caaacagggt gccccaaaca ttgtatgtac
    14041 acagccattt gcctgcctgc caaaccacgt tgtaggtaag ggtgttatca aggaactgcg
    14101 ccgtaagtat ccggaatcta atatcgtcgc aattgactac gatccgggag caagcgaagt
    14161 aaaccaggta aaccgaatta aattgatgct ggcaacagcg gagaagaagt tgaaatctga
    14221 tttgccgcag gcaagataga cgccaaacaa acgccctctg agaatgaaat ggtatgctcc
    14281 cttttaggta gacagttgaa aaaaataaaa ctgtttatct g
//
