LOCUS       gnlProkkaKIIOHMHI_14   14905 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIIOHMHI_14.
ACCESSION   gnlProkkaKIIOHMHI_14
VERSION     gnlProkkaKIIOHMHI_14
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:09:38
            Original ID  :: gnl|Prokka|KIIOHMHI_14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 22528
            Orig. end    :: 37433
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14905
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12682]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12682
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14905
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14905
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             87..1238
                     /locus_tag="ctg14_18"
                     /transl_table=11
                     /translation="MEIIKDLPEVFEEFAEQRKNSFLAIKKIKDQNIPVIGSYCTYFPQ
                     EIAMAMGAASVGLCSMSDETIPVAEQTLPKNLCPLIKASYGFAVTDKCPFFYFSDVVVG
                     ETTCDGKKKMYEFMSEFKDVFILELPHKQTEAALQYWKSEIIRFKEYLEKKFEVEITEE
                     KLREAVRISNEGRRALKDFYELMKQDPAPMKGENLYNVLYGTTFKFDRSKVPAEIDALT
                     VKLKEEYAAGKNEGKKHRILITGCPMGGATMKVVKAIEENGGVVVAFENCSGAKSVDRL
                     IDENDPDIYEAIARRYLNIGCSVMTPNPNRFELLNELIDEYQVEAVVEMTLQACHTYNV
                     EAGKVGRFVREEKKIPYLHVETDYSQSDVGQLNTRIAALIEML"
     CDS             complement(1498..1611)
                     /gene="allorf_24026_24139"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_24026_24139"
                     /protein_id="allorf_24026_24139"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTCCLMVMNIRKALSAGKIHPTERASVFCPYFLVSGL"
     CDS_motif       complement(1561..1611)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MTCCLMVMNIRKALSAG"
                     /locus_tag="allorf_24026_24139_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1498..1560)
                     /prepeptide="core"
                     /locus_tag="allorf_24026_24139_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="2210.6"
                     /monoisotopic_mass="2209.2"
                     /core_sequence="KIHPTERASVFCPYFLVSGL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTCCLMVMNIRKALSAG"
                     /leader_location="[1560:1611](-)"
                     /alternative_weights="2228.6"
                     /alternative_weights="2246.6"
     CDS             1844..4384
                     /locus_tag="ctg14_19"
                     /transl_table=11
                     /translation="MTDMVLPGGEIGTEYQVQLEADTDVSWSLEEGSELPAGLTLSSGG
                     VISGTPQKEGSFSFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALINLGIH
                     AEGEQSRKRLFLYNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDGEMQPGSCAAVDIDD
                     KKDLPAGNYEETVTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDP
                     EFRVEKYVVVRNSGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLY
                     FYILPKQEYGIYDETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQW
                     GYKTLPEAKTYILKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSV
                     GKYSFQVTVTAKTVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADAL
                     HLPKSLEVYGAEVNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEG
                     LDTAVQIMVQVDAYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDL
                     KEGNYTAQTKITNSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVK
                     AKTPDAPVVQKVQVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGS
                     SKELILRGVPAGTWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKV
                     SRQGTKRNVAVTFTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFK
                     NVKPGVYYLAGRAYVKGYAKSYTKWSKIKKIVVK"
     CDS             4666..5424
                     /locus_tag="ctg14_20"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTFDGKENSNQTADKKTKVFASSNNAGDVQNSGNGTDGTAG
                     TDTDDSQTTGVDTSTSEDNGSTGNDGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5566..6459)
                     /locus_tag="ctg14_21"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQNYYNFPWDCVLRYTKDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(6646..6981)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg14_22"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7100..7654
                     /locus_tag="ctg14_23"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7660..8367
                     /locus_tag="ctg14_24"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIQMPGENGIEAAREIRRLYPDSVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLLQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             8364..8471
                     /locus_tag="ctg14_25"
                     /transl_table=11
                     /translation="MKNAESFIVWAGNVYGDWDRCLDIWTDVSEKKYGN"
     CDS             8443..9840
                     /locus_tag="ctg14_26"
                     /transl_table=11
                     /translation="MFPKRSMETEKDKTVWKIILIILLYFTAYSFCGSYLENNIETKKT
                     ILIILLVLGVICLIPDCVVRLKRIRNFQNVLFFVMIVVLVTCQYWTAYISGNVIVFGNL
                     YLPIFLTIFFQCTFIQSYIWEFLYLTNIGLLKLLYIITVCVIKKRKIGEYIYFQNMHSY
                     SSGIYLLVISVVIILLLKLFRVNKYAGDIFRGNQKFFYGFALVEYILLYFLLGIQNKIL
                     KIENLVITIVVVSGIAVVLMILFMFFFVKSVNIEKNILEVKNRAVEQQYQELEDAYQKY
                     RCIIHDQKHMLSFIQECIENKDLNGIAAYVADNQKKFRDEEKKFWTGIDVLDKTITMKK
                     RKMDALDINFELDASVDDTIINTTDLVIILSNLFDNAIDAAVKSKEKKICLRIKNINDV
                     LMMKMWNTSTRIPDVKRGKFVTDKLEAEGHGWGIESVKRLVKRYDGNITFKYDSDFFQV
                     IIILSKS"
     CDS             9856..9984
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_27"
                     /transl_table=11
                     /translation="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNGSFFSICC"
     CDS_motif       9856..9960
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /locus_tag="ctg14_27_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9961..9984
                     /prepeptide="core"
                     /locus_tag="ctg14_27_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="769.9"
                     /monoisotopic_mass="769.3"
                     /core_sequence="SFFSICC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /leader_location="[9855:9960](+)"
     CDS             10001..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.4; E-value: 5.9e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_28"
                     /sec_met_domain="DUF4135 (E-value: 1.7e-93, bitscore:
                     304.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-52, bitscore:
                     169.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFNHYNNAISERIFILSIHEQKAKGNLKGNTSEEQYDYYEKKY
                     LNNATYIKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKFSGT
                     VGIYMSKGDTHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISCRTV
                     QYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHGEYP
                     VIIDMETYPGYLKQQSEKDGSSVEEKISKSTEIKLANSVIHTGMLPVLTWGRGNSRVLI
                     SAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTECII
                     RGFCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRECRKA
                     LLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPCTPY
                     ESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYNTDKERKIYSQIR
                     KIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHDFEE
                     KNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTGKRV
                     WMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEKDLW
                     KKGQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAMLYECDHKVEYADKIQLLLRYED
                     SLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADS
                     LFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGT
                     EYLNLAFMNGISGTGMALMEIL"
     CDS             complement(12735..13250)
                     /locus_tag="ctg14_29"
                     /transl_table=11
                     /translation="MKTLTELIQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDSTQE
                     LYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSLQAP
                     DSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIAQKLKLSRQYVNRMKKKLI
                     LRYISENK"
     CDS             13551..13781
                     /locus_tag="ctg14_30"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             14384..14905
                     /locus_tag="ctg14_31"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKST"
ORIGIN
        1 gaggataata aggactgcaa cagttggcga atggtatgaa agaagtaaaa aataatataa
       61 aaacgataga aagatgaggt acaaagatgg aaataattaa agatttacca gaagtatttg
      121 aggagtttgc ggagcagagg aagaattcat ttcttgctat caagaagatt aaggatcaga
      181 atatcccggt aattggttct tactgtacat attttccaca ggagattgca atggccatgg
      241 gagctgcttc tgtaggttta tgttccatgt ctgatgaaac aatcccggta gccgagcaga
      301 cattgccgaa aaatctctgt ccactgatca aggccagtta tgggtttgca gtgacagata
      361 aatgtccatt cttttatttt tcagatgttg tagttggtga aactacctgt gacggaaaga
      421 aaaaaatgta tgaatttatg tccgaattta aggatgtatt tattctggag cttcctcata
      481 aacagacaga ggctgcactt cagtactgga agagtgagat tatccgtttc aaagaatatc
      541 tggagaagaa atttgaggtg gagatcacag aggagaagct tcgtgaggca gtccgcatca
      601 gcaatgaggg acgtcgtgct ttgaaagatt tctatgaact gatgaaacag gatccggctc
      661 caatgaaggg tgagaatctt tataatgtat tgtatggaac tacctttaag tttgaccgtt
      721 ccaaagtccc ggcagagatt gatgcactga cagtgaagct gaaagaagaa tatgcagcag
      781 gcaaaaacga aggaaagaaa catcgtattc tgatcaccgg atgtccaatg ggcggagcta
      841 ccatgaaagt agtaaaagca attgaagaaa atggcggtgt ggtagttgct tttgaaaact
      901 gctccggtgc aaagagcgta gacagactga ttgatgaaaa tgatccggat atttacgaag
      961 caattgcaag acgttatctg aatatcggct gttctgttat gactccgaat ccgaaccgtt
     1021 ttgaactgtt aaatgaactg atcgatgagt atcaggtaga agctgttgtg gaaatgactc
     1081 ttcaggcctg tcatacttat aatgtggaag ccggtaaagt tggcagattt gtaagagaag
     1141 agaaaaagat tccttatctg catgtggaga cagattattc tcagtctgat gttggacagc
     1201 taaatacacg tattgcggct ctgatagaaa tgttataact gtgaaggtat tataagatta
     1261 tacgaaaaat gtcgaattgt atgtatttta ttatagcaat cctttgaaat aatgcatctt
     1321 aatccagccc atcagagtgt gaaatcctgc gtcagatatc tttgccgtgc gtcagcacgc
     1381 ctgcagatat cttccttgtc tttcgcgctc tgctgaactg tcttaaatgc attatttacg
     1441 aggattgcta tagaaaaaaa tatgtataag caataaatga caagcgactg atcaaattta
     1501 taaaccagaa actaaaaaat atggacagaa aacagaagct ctctctgtgg gatgaatttt
     1561 tccggcggac agggcttttc tgatattcat gaccattaga caacatgtca ttccgtaatt
     1621 acagaaacat tcccgtccag tggtatatta atattaatta ggtaaattga tacttttata
     1681 ttttattatc tggaggagaa gaatgaaaag taattacaaa atttttacag cagttttttt
     1741 atcggcaatt atgacagcag cagctccgtt aacagtatgc ggggcggaag ttttttcggc
     1801 gggagaatct ttcagtgatg gaacagggag tattcctgcc atattgacag atatggttct
     1861 gccgggtgga gagattggaa cagaatatca ggtacagctt gaagctgata cagatgtgag
     1921 ctggagtctg gaggagggaa gcgagcttcc ggcgggactt acgttgtctt ccgggggagt
     1981 gatcagcgga acaccgcaga aggaagggag tttcagcttt actgtacagg cggacaatgg
     2041 tattggagtt tcttcacagg aactgagcct ttatgttgca cagcgtgagc aggaacctgt
     2101 tataaagcag tatgagctga catcaggtac tgctttgatc aatctgggaa ttcatgcaga
     2161 gggagaacag tcacgtaagc ggttatttct ttataatgca ggaacagatt cgcttcatct
     2221 ctctgatttt ccgcagagca gatattttga tttttcctac gcaccgattt tcgatacaaa
     2281 tacggatgga gaaatgcagc ccggaagttg tgcggctgtg gacattgatg ataagaagga
     2341 tctgcctgcc ggaaattatg aagagacagt gacatttgag acaaaagagg gtgcttcctg
     2401 taaggttact ctgaaagtaa ttgtgggagc ttcctctgaa aaagattatg agctgagtat
     2461 agaaacaggt acagaagaag aatttacaga aagcgatttc tatgacccgg aatttcgtgt
     2521 ggagaagtat gtagtggtca gaaattcagg aaaaaaggaa accagaatac ggatagatac
     2581 ttctggtctt aagaattttg aagtggatga ccagatggca aagtggacag aagattatga
     2641 ggaacaggat tccaaaaagc tgctgaaacc gggagaaacg ctttattttt atatattgcc
     2701 gaagcaggaa tacggaattt atgatgaaac gtttgcattt ctcgcagatg acggaagcag
     2761 atatcctctt catgttacaa tgaacagaga gaagaatccg acagaaaaga agcagctgga
     2821 aattactgaa aagtctgccg ggggttttcc gacaatgcag tggggctata agacacttcc
     2881 ggaagcaaag acatatattc tgaaaaatgt tactgataca gatatgaagc tgtcttttaa
     2941 ccgtagtaaa gaatgtagtg tgttattatc tggaaatgct tatctggcac caggggagag
     3001 cacagaactg agactctggc ccaaactggg gctttcggtg ggaaaatata gttttcaggt
     3061 gactgtgact gcgaaaacag tggcaggaga acacctgaca acgcagaatc tgtataattc
     3121 ttttattgta ggagaccgga cttatcaggg actggcagat gctgttgcgc ctgtgaccgg
     3181 aattaccaat ggtgcagaaa aaactgctga tgctttgcat ctgccgaagt cgctggaagt
     3241 ctatggcgcc gaggtgaatg gagagaaaac aacattttct gcgtctgtga agtgggatgt
     3301 ggagaattgt gcttatgatc cgaaaagcaa ggcagctcaa agttttctgg tcaacggatc
     3361 tctggaactg aatgaggatg aaaataatga agggctggac actgccgtac agataatggt
     3421 acaggtggat gcttatcaga cattaaacag accagttatt gatacgcggt ggaccagagt
     3481 gatcacaaat tatgcaatgc tttatctgag agatctttcc aatgaagcgg acggctatca
     3541 gtttgtgaca gccaaatctc agaaggatct gaaagagggg aattatactg cgcagacaaa
     3601 aattacaaat tctgaactga atcaatatcc tgagctgaag tatattccgg agggaacaca
     3661 tagtctttat tgcagggcat acaaagagaa cagcagccat gttatggaat atggggaatg
     3721 gtcagacggg gttccggtta cggtaaaggc aaagactccg gacgcacctg tggttcagaa
     3781 ggtgcaggtg aagaaaaatg atgtcagaat agtacttaac agcaagggtg aggaaccgga
     3841 cggttacgat gttgttgctg ccagaagtaa gaacggaaaa gaaccatcgg attatataaa
     3901 ggtaaagagt gggtattccg gaagcagtaa agagcttatc ttacggggcg taccggcagg
     3961 aacgtggtat attggcgtac atgcttataa atatctgaat gggagcaata ccaaagtgct
     4021 cagtaaatgg gcagaggtca ggaaggtaac tgtaaaaaca agccttgtaa caggaaaacc
     4081 tgctgttaaa tcagctaagg tttccagaca gggaacaaaa agaaacgtgg cggtgacgtt
     4141 tactgttcca aagtcctgtg atggaacaga ctgggtactg gcaaagaaag tttccaaatc
     4201 tgataatggc agctatactg gtgtaagcag ttatgcttac acaaagaaaa atcagacaaa
     4261 aaccacggtg gtctttaaaa atgtgaagcc cggagtctac taccttgcag gacgtgccta
     4321 tgtaaaaggc tatgcaaaaa gttatacgaa atggtcgaaa ataaagaaaa tagttgtgaa
     4381 ataagcactg ctgtcatttg tttcacagag atttcacttt taagaagaaa aatccccctt
     4441 ttaccaggcg tttatacctg ctttttcctg taatactcaa agtttacggt actgccactt
     4501 attatactca aatcttgtct gaatttggag ataaataatg tcctttttat gacagataag
     4561 ggacatatga ggcatcgaag cctgtggagt atgtaataat gaacaggaaa agcacattat
     4621 gataaaggca atgacatttt tagtaaatgt agaaaggaca acaaaatgaa gcagaaaaag
     4681 attgtaatta ttatggcagg gattttagca gcagcggctg ctatgacggg ctgcgcggaa
     4741 cagaataaaa cagcgacaca ggttgattat acgcagaact cacaggggaa atccgaacag
     4801 acaaaacaaa aaacagcaga aaaatctcag ccggataaaa aacaggtaaa taaaagtaca
     4861 ttcgatggaa aagaaaattc aaatcagact gcggataaga agacgaaagt atttgcctca
     4921 tccaataatg cgggcgatgt acagaattca gggaatggaa cagacggtac tgcgggaact
     4981 gatacagatg attcccagac cacaggggtg gacacttcta catctgaaga taatggttca
     5041 acaggtaatg atggtactca atctgaccag agggcagatc aggcaatgat atatgacagt
     5101 gagggaaatg gaaggctgat ttctgaagct gatgatggaa actggtatga cagtgacgga
     5161 aattactatg gaagctggga agatattgaa gatgctatgg taaatgaaaa tggtgtcaca
     5221 gatcaggatg gcaataaata ttactggaca gcacctcacg atgcatcaga agaggtcaca
     5281 gatccgtatg acctgtattc ctgggatccg ggaaccaatt cctatatacc gtttcaggct
     5341 gcggaatctg actgtagtcc tataggcaga ggaaacggct ggtattacta tgatgaagac
     5401 agcggcgaat atgttccgtg gtaaaaataa gaaaacaaaa gaaacagttt tgaaatcatt
     5461 ttgatgggtt tcaaaactgt ttctttttat atacaagaaa tagtgaaggg gcatatccgg
     5521 cagaatcagt gaaaagaatt ctgccggatg tttatctggt aaagatcagc tgatcagttt
     5581 caggaaagta tttctgtcac aggttccgga aaccgttaag ccctgtgcct tctggaatgc
     5641 ctttacagca gagagaagtc ctgagccaaa ggtaccggga atctctacac cgtttggatc
     5701 ataagcacgt aaaagaagga gaatctcagc ggcagttacc atatattgtg tttcaccatt
     5761 ttttacataa tgctgtccaa gagcattgtc tgtgtttgtt ccccagatac cgtctacatc
     5821 cagaccggca ccataatccc tgttcagagc tgtctgaaga actttaacgc ctgctttttt
     5881 ggtagcagcg tctctttttc cggtaataga gattcctgca ttggcgaact tattggcata
     5941 accctgacct ttgcggattt ttgcatttcc tgcagttggc tgaggttcag gatcaggatc
     6001 agtagttgaa gaatctttag tataacggag aacacaatcc caagggaaat tgtaataatt
     6061 ctgaagtttg atctcttttc cactctgatc tccgggttta ccaccatgat atccattatt
     6121 ttcatttttg ctggcagata ccacctgacc attgccaatg tgcattactg tatgacttgc
     6181 gatgtttaat aatacgtcac cacgtttcat gccacttcct gtgctgagat taactttgga
     6241 agtcacatcc ttaaagccgc aggacagaaa gacggatttc atatttcctg tataagtggc
     6301 tccttttgtt tttacaggaa caccagcctg ctgccatgcg gagattacca gtgaagaaca
     6361 atcgtagtcc ggtccccatc tgttatcctg atcatatccg tgtgccggat cgtttgcgat
     6421 ttcaattgcc catgttactg ctttttctgt ttttgtcatt tttttatcct cctgaaattt
     6481 gattatttat ttgctcaccg gtgatacatc ttataaagag tgagaaaagg gaaaaatgta
     6541 aacatgaaac agaaaaaata aaaagcattt cctgattgtt gcttcgaggt cagaaaaatg
     6601 cttttcgagg acaaaaacac gaaaattgtc gaattgtaat tatatttaat cctgatgaga
     6661 ggcctggtat attttcagta tttttacaat gtattcagtc tggcgttcac ccatttgatt
     6721 catgattgaa attgcatcct gaatagccgg gctttgaata tctttattat gaggaagcag
     6781 atcataaaga aaatagtcaa gtcccacatc aagaatttca gaaagcttaa ggagattttc
     6841 aatagtaggc atatacttac ctgtttcaat ccggctgatc gtacttacag ataaaccact
     6901 taattcttcc aggtgttcct gggtaatatt tctgttgatc cgagcttctg caattctttt
     6961 tccgatagta ttgtttttca taaataaaaa tcctttcctt tgataaagtt taacagacgg
     7021 aattaaatat gtataaggat ataaatgaca agcgactaat caaatttgat atgttttatg
     7081 acaggaggaa tataggaata tggacgaata tacaaaggat ttgtatacca tgatgttttc
     7141 tttgcagact ttgcaaaatc agggaattac aatcagagaa actgtatata aaagtctgga
     7201 caaattactg ttatggaata aagaatctga aaacagtaaa tatctcgaat tagcgttgct
     7261 tcatatgcag gcttatgcta atatgggatt tgctttagat gaagaaaata agacaatacg
     7321 tgagatatta aaaaagacag gaaagaccag agaagacttt ttcccgaaag gatatcttct
     7381 tggaaagaga attaaactga ccaagtcaca ggttcgtggt atgattggaa gatggagacc
     7441 ttccagagac agtccgatga caatcggaga actggtggat gatatcatca gaaaggtaaa
     7501 aaaccatgag gaaggcagat acatttatca gtatcacaga actgatgtga caaccaaagg
     7561 ggatatcgag gtttatgagc tggtcatcaa taaggatgaa agttattttt atgatgtgaa
     7621 gaaattcaga ttttatacat tcatggagga ataattgcta tgataagaat aatgattctg
     7681 gatgatgacg aaatgtatct gaaaaaagaa aaggatatca cagaacagta ttttgcagag
     7741 aaaaacgtag attgcacggt aacgatatac cagaatgtgg aatggtttct gctgggattg
     7801 aatgaagaaa aattcgatat gtatattctg gatatccaga tgcctggaga aaacggaata
     7861 gaggcagcga gggaaattcg cagactttat ccggattcgg ttattatatt tattacaaat
     7921 tttgtggatt atgcaataga agcatatgag gtaaacacct atcgttatat tcccaaagag
     7981 tgtctgaagg aaaaacttct gcaggcttat gatgcgcttc ttcctggaat tatggagaaa
     8041 gaagagcggt actatatcat aaataaaaga aatgaagttg aaaaactggc atattctgat
     8101 attttctata tgaaaaaaga aggaaaatat gtgatttttg tgcacaggcg tggggaagta
     8161 aagatcagag caagtctgtc aacagtagaa aaagaactga attcaaaaga atttattata
     8221 tctgacagag gatatcttgc aaacatccaa catgtgatga agatgaaagg aagggatctt
     8281 tatatgcggg acggtaatat tattacagtt ggcagagaaa gattcaaagg tgtcagagaa
     8341 gcaattctga attactgggg ggtatgaaga atgctgaaag ttttattgta tgggctggca
     8401 acgtttatgg agactgggat aggtgtctgg atatttggac agatgtttcc gaaaagaagt
     8461 atggaaactg aaaaagataa aacggtatgg aagataatat taattatact gttatatttt
     8521 acagcatatt cattttgcgg atcatattta gaaaataata tagagacaaa aaaaacaata
     8581 cttattatat tactggtgct gggggtaata tgtttaatac cggattgtgt agttaggtta
     8641 aaaagaataa gaaattttca aaatgtgctt ttttttgtta tgattgttgt tcttgtgacc
     8701 tgtcaatatt ggacagcgta tatatctgga aatgtaatag tatttggaaa tctatatctt
     8761 ccgatatttt tgacaatttt ttttcagtgc acatttattc aatcttatat ttgggaattt
     8821 ttatatttga ctaatatagg gctattaaaa ttattatata ttatcacagt ttgcgtgatt
     8881 aaaaaaagaa aaataggaga atatatttat ttccaaaata tgcactctta tagctcagga
     8941 atttatttgc tggttataag cgttgtgata attttgttat taaaattgtt tcgcgtaaat
     9001 aaatatgctg gtgacatttt tagaggtaat caaaaatttt tctatggttt tgcattagtc
     9061 gaatatatac ttttgtattt tttgctaggc atacaaaata aaatccttaa aatagagaat
     9121 ttggtaatta ctatagtagt agtatcagga attgccgtag tattgatgat tttatttatg
     9181 tttttttttg ttaaaagtgt taatatagaa aaaaatattt tggaggtgaa aaatagagct
     9241 gtagagcagc aatatcagga attagaagat gcatatcaaa aatatagatg tattatacat
     9301 gatcaaaagc atatgttaag ttttatacag gagtgtatag aaaacaaaga cttaaatgga
     9361 attgcggcat atgttgcaga taatcagaaa aagttcagag atgaagaaaa aaagttttgg
     9421 acaggtatag atgtacttga caaaacaatt actatgaaaa aaagaaaaat ggatgctttg
     9481 gatataaatt ttgaattaga tgcttcggtg gatgatacga ttataaatac tactgatttg
     9541 gttattatat taagcaattt atttgataat gcaatagatg cggctgttaa gagtaaggaa
     9601 aagaagattt gtttaagaat aaagaatata aatgatgtat tgatgatgaa aatgtggaat
     9661 acaagtacga gaattcctga tgtaaaacgc ggaaaatttg taacagataa attagaagcg
     9721 gaaggtcatg gatggggaat tgaaagtgta aaacgacttg taaaaagata tgatggaaat
     9781 atcacattta aatatgattc tgattttttt caggtaatta ttattttaag taaaagttaa
     9841 aggagagata aaaaaatgac agaagaattt attggatgta ttgaggaaga acttaaggaa
     9901 atagaactgt tttatgaaga aaatggagta gaagtggaag catatacttt acataacgga
     9961 tctttttttt caatatgttg ttaaaggaaa tagaaaaggt atgccagact ttaatcatta
    10021 taataatgcg atatcagaac ggatttttat attgagtatt catgaacaaa aggcgaaagg
    10081 caatctaaaa ggaaatactt ctgaagaaca atatgattat tatgaaaaaa aatatcttaa
    10141 caatgcaaca tatataaaat ctttactgca ggaatatccc gagttaaaac gtctgcttga
    10201 attaaaaaat aactctatcc agagagcaga atgtgaaatc aggaaatctc tttatgcaga
    10261 aaaagaacag atacaaaaaa tattctgtga tggaagaaag ttttccggga ctgtgggaat
    10321 ttacatgtcg aaaggcgata cacacagagg aggacgaagt gtggcaaagg tagaattgga
    10381 taatggaaca attctgtact ataagccaca tagtcttgat aagaatataa aatatcagga
    10441 actttataac tatttatgca gaaaaacagg aatttcctgc aggacggtac aatatttatc
    10501 tcatgattcc tatggatggg aagaaaaaat tgagaatatt ccctgtaaaa acgaaagtga
    10561 ggtggagcat tattatttca gaatgggcat acatctgttt ttgggatatg cccttggagc
    10621 aacagatctt catggtgaaa atattatcgc acatggagaa tatcctgtga ttatcgatat
    10681 ggaaacgtat ccgggatatt taaaacaaca atcagaaaaa gacggaagta gtgtagaaga
    10741 aaaaataagc aaaagtacag aaataaaatt ggcaaattcg gttatacata caggaatgct
    10801 ccctgttctc acatggggca gaggaaacag cagagttctt ataagtgcaa tgggaacaga
    10861 ggaaaagata aaaacgccgt ttaaacttcc tgtggtaaag gatgataaaa catctgatat
    10921 tcacatagaa tatgaacctg tggaaatgca gataaaggaa tgcattgtaa gactaaatga
    10981 tcaggttatc aatgcggcag attatacgga atgcattatc agaggatttt gcagagcgta
    11041 catggtgaca atggcagata agaaagtgga ggtgatgttg tccggctttt ttgacggacg
    11101 ttccagagtt gtactgcggc atacccaaca gtatgcaatg tatcttatgg cttcgtttca
    11161 tccggattat atgaagtcaa gagaatgcag gaaagctctt ttgaatgtga ttcacaaaga
    11221 gggggaatct tcttttatga aagagattca tgattatgaa attgacagcc ttctggaaat
    11281 ggatataccc tgctttgaga ttgatgcgaa cagcagatct gtttatgatg gaaatggcgg
    11341 agaacataaa gagtatctgc catgtactcc ttatgagtca tggcgaatgc atatgaagca
    11401 gatgagttac tctgatatgg aatgtcagtg tgattatatc aggctgtcta tggaaatgct
    11461 gaaggcatct gatggaaaga aaaagatgtt tccgaccagg ataaagggat ataacacaga
    11521 taaagagcgc aaaatataca gtcagatcag aaagatagtt catcgaatct gcagcagagc
    11581 aattatccgg gaacagagcg ccggctgggc gggtctgcaa ttctgggata atggtcactg
    11641 gaacctcaga tcaggtggaa tatatttata tgatggaata tccgggatag tcttgtttct
    11701 tgcaaaatat cttcatgatt ttgaagaaaa gaatgcaagt gcagaagaaa tttatcatct
    11761 tgctgttttg agattgaaag cttatacaga tgaaatacac aaaaaacaga tttatgataa
    11821 aaatcttctg acaggtattg taaatggaga aagctcggtg gtatatacct atctttatct
    11881 gtttaaactt acaggaaaaa gagtgtggat gatttatgcg gaaaagcatt tcagcattat
    11941 tgagagggta tggaaagaag attcacaact ggattatctg agcggaaatg ccggagctat
    12001 tgtagtggca gtgatgttat ataaagaaac cggaaatctg aaatattatg aaatagcggc
    12061 agatatggaa aaagatttgt ggaagaaagg acaggaaacc ggaaatggat acggatggag
    12121 attaaaagga acagacggac cgctggctgg aatgtctcat ggcaacagtg gatttatgat
    12181 ggcttatgca atgttgtatg aatgtgatca taaagtggaa tatgctgata aaatacagct
    12241 tttgctgaga tatgaggatt ctctgtactc agagaaagcc ggaaactgga aggatttacg
    12301 agagagttca ggggaaagct tcatgaatgc atggtgccat ggggcgccgg gaatcctgct
    12361 ttcacgaatg aaactggaag agctgtttcc cgaggatatg cagattaaaa aagacaggtt
    12421 aaatgctgca gactctttgt tttatggaga acaggatgaa aaaatttgtc tgtgtcatgg
    12481 gatgtccggg aatttactta ttatgaagaa gtatcttcga aaatatggta acaaaaaaat
    12541 gaaggagcaa tatgaggcgt tatgtgactg ccttttattt caactggatc acccggcaaa
    12601 aatatctggg acagaatatc tgaatctggc ttttatgaat ggcatttccg gtacgggaat
    12661 ggcattaatg gaaattttat gaaaactaag ggaacacctg cagactgtaa atttatggtc
    12721 agcaggtgtt tcttttattt gttttcggaa atatatctga gaattagttt cttcttcatc
    12781 cgattgacgt actggcggga cagcttcagt ttctgagcaa tctgggcatc gcttttatcc
    12841 tgataaaagt acatggacag aatttttctc tggacactgt ccgaagggta agagttgata
    12901 tatgcggtta catcataata ggtgtcatca aaactgtcgg gagcctgtaa tgaaacagaa
    12961 caagaatcaa aatcatcttt ttcaggttcg gaaagacaac tgcggcaaag ggaacgatat
    13021 ctgttttcga cagaggtctg catgtatctg atacattcac cttctgagga tgaagaactt
    13081 aaatatggca atgtctttaa cagagtaaga tacaattcct gtgtggaatc ttcgcgttcc
    13141 atgcagtgaa tccgggatgc atatcctttc acaagcggtt ccatacgttt gagaatttca
    13201 ctgtctgaat ctgggatacc attttggata agttctgtca gtgttttcat aggtatctac
    13261 ctccttttta ggggaagtag taagaaaact gctgatcaga aactaaaaaa gaaaaaaatt
    13321 tgtgagttta caaatggaag agaaaaaact ctttattaag tgaggttgca aatttagatc
    13381 agcgatagga gaagaaatac atggtaaaaa gagatttgca aaataattgt agagaataga
    13441 aatatgcttt aaattaaaac ggtaataata agattagaaa agacttttag tagacaaaac
    13501 atagaaaaag tttgcataat aaaagaagat taaggaagga ggcagaaacc atggaaacaa
    13561 cggttatgaa tgtggcagtt tcacagggaa tctgggctgt gcttgcggtt tttcttctga
    13621 tttacattgt gaaatcaaat gaacagaggg atacaaagca ggaagaacga gagaaaaatt
    13681 accagacggt gattgagagt ttaactgaga aatttcagat tctgaatcag gttcaaagcg
    13741 atctgaaaga gattaaggat aatcttttta acaaaaatta aatagggaaa agaaaaaagc
    13801 cttttctgca ggatatattt ttccagcgga gagggcttct gtcattttag gtaagaaaat
    13861 aggttaattt gagaaaaata tgtttactaa aatggtagat gaatataagc ataacattcg
    13921 tgtccattag aatactttta atcccagatt tacagatgtt cgtatagtaa atggtatatt
    13981 atgataataa aacctgactt ttgggtagtg taaaatagat taaaaaaaat ggccgcaatc
    14041 caagtgttta tgcgagggtg taaaaattct tgtgtctatg gaaagtaaat ctttctgata
    14101 agaaatagat atgtaaaatt ttgctgtcga attaatgatt atgcggctgt cgaatatatc
    14161 tttgtactta cagtattgcc atgtaggaaa attatataca tcattttcga tttttttgca
    14221 tgacaagtaa ggcatcatga ttaccttaac ttccaaaaat gagtagccct aacgaaaata
    14281 aaattttaaa aaagcccgta tttctgcgga aattattgca aaaatacggg ttgtgctgta
    14341 caataaattt agggctatat aaacctgaat aaaggaggca aatatgtacc tgaaatcaag
    14401 agttaagcta ccggatgtgc atggaaaatt gacccgatta agacgcgggg atatcacata
    14461 tattaagtat gagtatgatc gctattatga tccggagaaa aaatatacct atccacagag
    14521 agcgactata ggcaaggtat gtccagatga tgacactatg atgattccta acgaagcctt
    14581 tctgaaatac tttccagatg cagtcttatc agggatggaa gaccggacag aacgtagcag
    14641 ctgtctgcgg gttggtacat atgctgtaat gcataaaata gtattggatt attcgttaga
    14701 caagctgctc ggacagttct tctctgagcg ggatatggca ttattgcttg accttgcctc
    14761 ttactctatt gtagaagaaa gcaatgtggc acagcattat ccggattacg catacaatca
    14821 tccactgtat agttctggta tgaagatcta tagtgatgcg tcggtaagtg atttctttaa
    14881 gagcatcacc aaggataaga gtaca
//
