LOCUS       c00082_gnlPro..        13888 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIIOHMHI_82.
ACCESSION   c00082_gnlPro..
VERSION     c00082_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:17:34
            Original ID  :: gnl|Prokka|KIIOHMHI_82
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13888
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13888
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3918:6862]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3919..6862
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13888
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13888
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(3..752)
                     /locus_tag="ctg82_1"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLDMAVDLMVKSEKISNREAYR
                     KQVYLREEESTTGIGEGIAIPHGKCDAVKKPGLAAMVIKNGVEFEALDDEPVTLLFLIA
                     APNTEDNIHLDVLSKLSVMLMDEEFTESLRNASSVDEFMDIIDRADSEKKDIDERLADT
                     GSTEGTQAKILAVTSCPTGIAHTYMAAEGIEKAAKAKNCFIKIETRGSGGAKNVLTDQE
                     IADADCIIVAADAKVPMERFDGKKVIEC"
     CDS             complement(770..1681)
                     /locus_tag="ctg82_2"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKEIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEELGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGIELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLARKEEIEAVYRQITEK"
     CDS             complement(2000..3415)
                     /locus_tag="ctg82_3"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             complement(3919..5598)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_4"
                     /sec_met_domain="HGD-D (E-value: 1e-17, bitscore: 54.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 8.4e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDEMMDWYAGELLGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(5591..6862)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_5"
                     /sec_met_domain="HGD-D (E-value: 2e-56, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWGAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             7107..8921
                     /locus_tag="ctg82_6"
                     /transl_table=11
                     /translation="MRSLAVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNKYIVQRFFILILMAALGLASSITAQFFAAKASVGFATKLRQAVYDHVQHLSFTEL
                     DTLGTDTLITRLTDDINQVQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFFSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAASAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKSLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             8918..10684
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     286.8; E-value: 2e-87)"
                     /gene_kind="resistance"
                     /locus_tag="ctg82_7"
                     /transl_table=11
                     /translation="MSRSTIKDPAKSKSSETFFKVLRFIGRYRFLLIFSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDTRGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNKELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGAFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEVSE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNSGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(10772..12559)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg82_8"
                     /sec_met_domain="Peptidase_M24 (E-value: 1.3e-43, bitscore:
                     138.4, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERITALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGMCLGFDGRTVSSKEASELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDSIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRLEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGEDFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDEFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVSELMSVRERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(12556..13404)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg82_9"
                     /sec_met_domain="ATP_bind_3 (E-value: 7.7e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLREAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIVKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
ORIGIN
        1 tgacattcaa ttactttttt accatcaaat cgttccatcg gaactttggc atctgctgca
       61 acaataatac aatctgcatc agcaatctcc tgatctgtca gcacattctt tgcaccgccg
      121 gatccgcggg tttcgatctt tataaaacag ttctttgctt ttgcagcttt ttcaattcct
      181 tctgctgcca tgtacgtatg tgcgataccg gtaggacaag aagtaacagc aaggatctta
      241 gcctgtgttc cttctgttga tccggtatct gccagtctct catcaatatc tttcttttca
      301 ctgtctgccc tgtcaataat atccataaac tcatctacag acgatgcatt gcgaagagat
      361 tctgtaaact cctcatccat cagcatcaca gagagcttgc tgagtacatc caggtgaatg
      421 ttatcctctg tattcggcgc tgcgatcagg aataataagg ttacaggttc atcatccagt
      481 gcctcaaact ctacaccatt tttgatgacc attgccgcaa gtcccggctt cttaactgca
      541 tcacatttac catgaggaat agcaattccc tcgccaatac ctgttgtgct ctcttcttct
      601 cttaaatata cctgtttacg ataagcctca cgattgctga tcttctcact ctttaccatc
      661 agatcaactg ccatatccag agtttctgac tttgttttcg gagcagctgt taacgatacg
      721 cttcgtctgt caagcaggtc tgttattctc atcttttctt ccccctttat tatttttcgg
      781 ttatctgacg ataaaccgct tctatttctt cttttcttgc aagattttca gaaaatgcac
      841 ttgcacttcc tgctgcaatt cccatgtgga atgcatgttc gtaatccttc ttctccatcc
      901 agcctgcaac gaatcctgct accatggaat ctcctgcacc cacaccattt accagcctgc
      961 cttttggtgc aggttcttca aatacctgtc catcctctgc taccagaact gcaccttcgc
     1021 cggccatgga gatcagcaca tttcttgcac ctttttcctg aagtttcttt ccataaggaa
     1081 ttacatcttt tcttgttttt aattctatac cgaagatctc gcccagttca tgattatttg
     1141 gttttacaag gaacggatga tatttcagga cattgaccag aagatccttt gtggcatcaa
     1201 ctacgatcat cacacctttt ccatccagcc ttgccatgat ctgttcatac atgtcatctg
     1261 gcatagaaga tggaatgctg cctgccagga aaagtacatc gccttctcca agctcttcca
     1321 gtttcttcat cagttcctct actttatcct tgctgatcac cggtcctgca ccattgatct
     1381 cggttccgtc aatagatttc agtttcagat tgatccttga aaccccttca ctaatctgaa
     1441 tgaactcaga tttcactccc atctcatgta atctacggat aatttctttc cctacaaacc
     1501 ctgcagtaaa tccaagtgca gtgttctcaa tcccaagatt cataaggact gtggaaacat
     1561 taattccctt tccccccgga agcatcagct ctgaacttgt tctgtttgtc agccccagtt
     1621 taaaatcatc taccgaaacg atatagtcca gagatggatt aaaagtcact gtgtaaatca
     1681 tctcttcttg ccctcccgtt ttatattggt atcctttcgg agtctttatt tcactttcac
     1741 caaaagattc caaaagtaca tattgtcatg tcttttctgc atgttcatga ctgttttttg
     1801 tttatgatct tagtatactg tcatattcat ccaaagtcaa tcaaactaat tcataaaaat
     1861 aatgactgct tttggttcac tttgcacaaa aaagtcataa tcagtcaaac gcaagcaaaa
     1921 aaatcctctg atcaggattg ctataaattc cataatcaga ggatttactg ttttctgtta
     1981 ttttattagt tttgattcct tacattttat gcttttctgc tgcaaagaac gcttttgttt
     2041 cttttacgat cactccactt aatgcaaaca atgcgatcat attcggaatc gccatcagtc
     2101 cgttgaagat atctgcgatc gtccatacag cacttactgt catgtacggt ccgataaata
     2161 ctgccagaat gtaaagccag cgatatgtaa ggattgtttt cttatgtccg tttgtcagat
     2221 attccagaca tctttcactg taataatccc atccaagaat tgtagtaaat gcaaagaata
     2281 ccagacagat cattaataca aatgcagaaa tctgtccagg gatcggaagt ccgtgctgga
     2341 atgcataagt tgttacctga acaccttcca gaccttctac ctgccatgca cctgtcagta
     2401 cgatggaaag acctgtcatt gtacagatca cgatcgtatc aataaatgta ccagtcatgc
     2461 ttacaagacc ctgacgtaca ggctcttttg tctgagctgc tgctgctgcg ataggtgcgc
     2521 taccaagacc tgcttcattt gaaaaaatac cacgagccac acctttctgc atggatacga
     2581 tcattgttcc taccacaccg cctgtcactg ctgacggatt aaaggctccc ttcacaactg
     2641 ttacgatagc tgccgggatc tctgtaatgt ttaaaagaat cagcgcaaca ctgaagatca
     2701 gatagatcac cgccataaac ggtacaataa tctggctgac tgttgcaatt cgtttcagac
     2761 caccgatgag gattgctgca acacaggctg caagaatcag ggaagaaatt acaactgccc
     2821 aggaatactc tccaaggaac ggaatattta cgcagtttga tttgttcgga tcaaagaagt
     2881 tctgaactgc actggaaata ccatttacct gactgaatgt accgattccg aaaagaccta
     2941 cacatacacc aaagaatgca aagatctttg caagccattt ccattttgtt cccatacctt
     3001 tctcaatata atagaaagga ccaccaaggc tgtgaccgtc ttctgctacc acacggtatt
     3061 tcactgcaag aagaccttcg gaaaattttg ttgccattcc gaagaatgct gccagaatca
     3121 tccagaataa agctccggga cctccggcac agacagcagt tgcaacaccg acgatattac
     3181 cggttccgat tgtggcgctc agtgctgtac ataaagctgc aaagctggaa atctcaccat
     3241 cgccttcttc ttcgttctta aacatccatt tcaatgcaag agggagtctt cgcatctgaa
     3301 gaagtccaag tctggcagtt aacaggatac cacctgccat gatcaggacc ataaggggca
     3361 cgccccagac cagattgtct actgttgtca aaaaagaatt gatcgcttcc cacataataa
     3421 taaatctcct ttttctttta aaaagtgtaa tatattgtac agctgggaaa caaagtaata
     3481 acagaccgtt tcaaaaatca gaagttcaga aaatactgtt catatagttc atatgaatca
     3541 gcggggatga taaagcatcc tctgtccttt tgcctgagag attcaagaca cgaatcagat
     3601 aaccatttgt gggcagctat tgataattcg tgttatttgc accttcggcc cccgatctaa
     3661 cgggtgtctc cagagaaacg atccatttgc agttcttccc tgcatccagg gaacctgaga
     3721 gttttactcc ttcggcgggt atagcctttt gtgtggcttc ctctttcctg caaacttcac
     3781 ctcgttaatt tgctgttact gtggtatact atagctctta aatttgaact cgtcaataga
     3841 aaattaaact tttataaaaa aagtataaaa attccagaga tttccacctt gtaaaatccc
     3901 tggatattta aataattttt atacatcagc catatcagcc gcaaacagtg ctgcgccaag
     3961 tgcaccgcaa agctgagcct tgtcactgat taccagcttt gttccaagct tctcttccag
     4021 tgtctttacc aggcccttat tcttagaaac accaccggtc atcatatatt tctcctcacc
     4081 gcccacacgt ctggtaaggg cggcagtctt tacggcaacc gccttattca ggccatggac
     4141 aatatcatct gttgccttat tctgggcgat cagggataca acttctgatt ctgcaaatac
     4201 tgtacacata ctggaaattg taatatcttc tttgaattcc agcccacatt cgctcatctg
     4261 atccagattc atttccatgg tacgtgccat catttccaga aatcgtccgg ttcctgccgc
     4321 acatttgtca ttcataacaa agtttgcaac tgcaccgttc tcatccagtc ggatcacctt
     4381 gctgtcctgt ccgccaatat caataacagt acggacttcc ggattcagga aatgcgcacc
     4441 tcttgcatga caggtgatct ctgtgatact cttatcacca tttttaatag ctgtacgtcc
     4501 gtatccagta gtaaccagcg catcaatatc ttctctctgc aatccggcct ccttcaatgc
     4561 ctctgcaagg gcacggtctg ctccgatagc agctcctgct cctgtaggca agataatgct
     4621 ggtcacaatc tcatgatctt tatttaaaat caccacatct gtactggtag aaccactgtc
     4681 aatccctgcg aaataacctt ttcccatttt tctctctcct tttgtgtctc catctatggt
     4741 ctgctccagt gtttcaggct gaatgctctc tgcaaaagct tccagtctgg taagaagctg
     4801 accgctgctc tgaatagtat aatctgattc aatttttaaa agaggtacat ctgtatggtt
     4861 cttgatctca gcatattcga agctgtaaaa atcacaaaac ttcactgtat gataaataat
     4921 tcctgcaaca gacggatcat tataaagctt cttacggcct gtcgggtcca tcatccgcat
     4981 acatggaatc tgccccagaa gctctcctgc ataccagtcc atcatttcat caaaagaagc
     5041 accctccggt ggaagtatat ttcccacaga acggttatgc acgcaggtat cattctctac
     5101 aggaagaggc atagctttgc tggtcatttc aaataattcc tgccccattc tggcgccaag
     5161 cactgcaata tgggactttg tgattttctc ctgtgcatgg aaagcagccc ggaattttcc
     5221 ggcatcaaac tctgtgcctt tgtactgtgc ataagccttc gccagccctt ttaactgtac
     5281 agccatacgc tctctgctac aggcactgtc acagtgaagc acatccaaaa tatagagaaa
     5341 atccagcttg ccgctttcaa gcagaatgtc atagacactc cggatagtat cacagcagct
     5401 caccaggaca agttccttga ttttcccctc catgactcct tccagaagtg tttttccaaa
     5461 accgcagata ttgggatgtg aaacctgatc ggccaggtca aatccctccg gcatatgatt
     5521 aaagttctca cattccccgc caagagattc cagaagttca attggggtat atttacagac
     5581 atagtaagtt ttattcattc tcagcacctc ccagcatttc cagaaaagct cccagcctgg
     5641 tggaagtctg tccttctcct ccatggcttc gatcacaccc gtcaccgtcc aggatcaaaa
     5701 ggggcagacc ggcttcctcg aacttcttct ttgcaagctg tgccgcacca agcgtatgtt
     5761 tacatcccca atgtccaaac cacacagcac cgtctgctcc tgcctgtttc gcatggcgga
     5821 taccggcttc aatccttcta agggcacttc cgttcagtga atgatatacc attctttctg
     5881 ccattgcttc aaaggggttc tcaggatcaa aatccggctc acaggtttct gcaagttcac
     5941 atcctacgat ctgggctttc tcactgaagc aaagctcctg gcgcactgca tccgaccaga
     6001 atggaatggt atgcatccag taaatgtgct tccctttcgc tgccggtgct ttcttaatat
     6061 cttcaagaag catctgtgta tacttctctt cttctgctgt tcccagaagg atattgtttg
     6121 tcattcctgc atacaagggt gtgaccagat cagagggcac atatctgtct gcacgcatct
     6181 gctgatattt tttgtaattc tccagagtcc gcttactgca ggcaagacgt tcctttaatc
     6241 tgtcctcaga gattgttttt cctgtatttt tttccagaaa tatttttaaa tcctttaact
     6301 gatctgccac atactgtaca ttctctgtgg tctgattcca tggtacatca atggcaaata
     6361 caggtacctg gtaaaaatct gccagggtac ggaaggtgag caggttagca tcgcaggtca
     6421 ggttggtata aacaatacat ttaggctttg gcagaagtcc tttctgcgct gcaccaagaa
     6481 atgtcttgtg ataactgcac agtgtctctg caattccctg attctctgcc tgctgcaaaa
     6541 atgccctctc tgctttgctt gcagaaagat agcaggaaaa tccttctaca ttatagggat
     6601 gtaatcccac ctcctgcatc atttcgcagg gtgtaaaaat acttacaata acagaatctt
     6661 ccggtttctg aaggggccac agcatggtat ccatcatcag gtttgcaaga tgcctgtctg
     6721 caggcatcag tctcttgtcc tgcatgtaac ggaacttcag attctgcgcc ccccaaccgg
     6781 tttttaacag ccggcgggct gactgaggct ttttatccgt cagattttcc acataatgac
     6841 caaatgtctc aataatctcc atagtctgtc tcttcctcat tatggtaata ataatttatc
     6901 aattgtcagt gcacaaatag tgccacggaa tattttaata atatcttttt ttgaagtcaa
     6961 gctgaatttt ctccaaagtt catctgtttt tgcacattct tcttgacaaa aaagtctcaa
     7021 atgatacact tttgaatgta ttatttttca aaaaaaggaa gaaataatat aggaaagatt
     7081 ttttacgaaa ggaaggaatt tttaaaatgc gttcattggc agtttattta aaaaactaca
     7141 aaaaagaaag catcctggcg ccatttttta aatttctgga ggttgtattt gacctgatcg
     7201 tgcctatcgt cattgcacag atcattgatg taggtattgc aaaccatgac aacaaataca
     7261 ttgtccagag attttttatt cttattttaa tggcagctct tggtcttgcc agcagcatta
     7321 cagctcagtt ctttgcagcc aaagccagcg tgggctttgc cactaaatta agacaggcag
     7381 tttatgacca tgtacagcat ctgtctttta cagagctgga taccctggga acagacaccc
     7441 tgatcacaag acttaccgac gatatcaatc aggtccagaa cggactgaac atggggcttc
     7501 gtcttcttct tcgaagtccg tttatcgtac ttggatccat ggtcatggca tttaccattg
     7561 attttaaatg tgccctggtt tttgctgttg cgatcccgtt tctgtttctg gttgtctttg
     7621 tcattatgtt tttcagtatt cctctgttta aaaaggtaca gggaaaactg gacacagtaa
     7681 ccggactgac cagagaaaac cttacaggcg tccgcgttat ccgtgcattc tgccgcgaaa
     7741 aagaggcagt tgcagaattt gatacccgca atcaggagct gacaaagtta aatctctttg
     7801 taggaaagct ttccgctttg ttaaatccgg tcacttatgt actgatcaat attgctactg
     7861 ttattctgat ccagaaagca ggagtagaag taaatcttgg cggtatgcag cagggacagg
     7921 ttgttgccct ttataactat atggctcaga tgatcgtgga actgatcaag cttgcctccc
     7981 tgatcatcac cctgaacaaa tctgcagcca gcgcaggacg tgtggcagat atcctgaaag
     8041 tgaaatctac tatggattac ccctcttcct ccacatattc tgctcagata tcgaaggacc
     8101 ttgcaacagc aactgctgat gcatcacttt ctgaaaatgc catcgtattc aatgacgtaa
     8161 cctttgagta cagcaaagcc ggtgccccca gtctttccca tatcagtttt tctgtaaaaa
     8221 agggacagac cgtaggtatt atcggtggta caggaagcgg aaaaaccact ctggtaaatc
     8281 tgatctccag attctatgat gccagcaaag gaactgttct gctggatggt cagaatattg
     8341 aaaattacac cagaagtgat ctccgctcca gaatcggcgt tgttccacag aaggcagctc
     8401 ttttcaaagg ctctatccga gacaatctga aatggggccg ggaagatgcc tctgacgagg
     8461 atctatggca ggcacttacc acagcacagg gaaaagaggt agtagagggt aaaccgggac
     8521 agcttgattt tatgctggaa cagaacggta aaagcctttc cggcggccag aaacaaagac
     8581 ttaccattgc ccgtgccctg gtaaaaaaac ctgaaatcct gattctggat gacagtgcca
     8641 gtgccctgga ctttgccact gatgcagcac tgcgtaagtc tctcaacaga cttgactgga
     8701 aagtaactac atttctggta tcccagcgtt cctccagcat tcagcaggca gacttgatcc
     8761 ttgtccttga taacggtact ctggcaggta agggtactca tgctgaactg ctgcgtacct
     8821 gtgatactta ccgggaaatc tacttctctc agtttccgga agaaagagcc agatactcct
     8881 ctgtatctgc aggtaatata atgaaggagg tgactgtatg agcagatcaa caataaaaga
     8941 tcctgctaaa agcaaaagca gcgaaacttt ttttaaagta ctgcgtttca tcggaagata
     9001 ccgttttctg ctgatcttca gtatcatact ggcagcagtt tccgttatcc ttcagctgta
     9061 tgtcccaatc ctgttcggaa atgccattga tcaggtcatt gcccaacatc aggtaaactt
     9121 cgaaatgatg tggtattacc tgtcacgtat ccttgtaatg gtcatcctct cttctgctgc
     9181 cacgtggctt atgaatgtga tcaataaccg catgacctac cagacagtaa aggatatacg
     9241 tgccaaagcc atccgacaca ttcaggtact tcccctctct taccttgacg gacacagtac
     9301 cggagatatc atcagccgta ttatcgcaga tacagatatt ctatccgatg gtatgctgct
     9361 tggatttacc cagctttttt ccggaatcgt aacgatcatc ggaacactga tcttcatgtt
     9421 ctccaaaaac ttctggatta cattgatggt cattgtcttg actcccgtaa gctttttggt
     9481 ggccaaattt atttcttccc ataccttcca gatgttccgg aagcaaagcg ataccagagg
     9541 gcgtcagact gctctcattg aagagatgat tggaaaccag aaggttgttc aggcttttgg
     9601 atatgaggaa aaatcttctg aacgctttgc aaaggttaac aaagaattac aggaatgcag
     9661 tctgaaggct gttttttaca gcagcctgac aaacccttcc acccgttttg tcaataatgt
     9721 tatttatgcc tgtgttgcac tggtgggtgc attcattatc cctggaggca gacttacagt
     9781 cggaggactt tccgtacttc tctcctatgc caaccagtat atgaaaccat tcaatgatat
     9841 cagttccgtt gttacagaac ttcagaatgc tcttgcctgt gcaggcagaa tcttcgatct
     9901 gctggaggag gaaccggaag ttgcagaggt ttctgagaca ctgaaagatg taaagggtga
     9961 agtagatatt aagaatgtgt gcttccatta tgatgaatca aagaaactga ttgaggactt
    10021 taatctccat gtaaaaccag gtatgcgcgt tgccattgta ggacctaccg gatgcggtaa
    10081 gtcaaccttt atcaaccttc tgatgagatt ctatgatgta aattccggat ctatttccgt
    10141 tgacggcaaa ccgatcagag acattacccg ccattctctc agaagcagct atggtatggt
    10201 gcttcaggaa acatggatca aaaacggaac tgtccgcgac aatatctcga ttggaaaacc
    10261 ggaagctaca gatactgaaa tcatcgaagc agccaagctt acccacagtt gggaatttat
    10321 ccggaggctt cctaaaggac tggacaccat gctcaacgaa gacagcttaa gccagggaca
    10381 gaaacagctg ctgtgtatca cacgagttat gctctgtctg cctccgatgc tgatcctgga
    10441 tgaagccact tccagtattg atacacgaac agaattacaa attcaggaag cgtttgaacg
    10501 aatgatggag ggaagaacaa gctttatcgt agctcacagg ctttcaacca tccgaaatgc
    10561 agatctgatt cttgttatga aagacggaag tatcattgag cagggtactc atgatgagct
    10621 gattgcaaaa ggtggatttt accatacttt atataacagc cagtttgcaa aagtttctga
    10681 ataaaacaag ccagataata aatcaaaaag gaacagctgt ccatcacggc tgttcctctt
    10741 tttgattttg taaaatgttt ttttattttt atcagattgc ccgggtagca tctttcagcc
    10801 attctttttc ttcttcgttc aaatacggag aaatcttctc atatacctgc gcatggtaat
    10861 cattgagaag gttacgttcc cggacactca tcagttccga caccactcca tccaggtcaa
    10921 aaggtaccat agtcagaaat tcaaagcaca taaactgacc atactctgtt ttttcagctt
    10981 ttttacagac catcagattt tcatgacgga ttccaaattc atcctctctg taatatcccg
    11041 gctcatcaga ggtgatcatt ccctcctcca gcactgcatt tccacccgga acaattttcc
    11101 atcggaagct attgggtcct tcatggacat tcagaagata tcctactcca tgaccggttc
    11161 catgtttaaa atcctctccc atttcccaca acggctgtct cgccagaata tccaggttta
    11221 caccggtaca gccatgaaga aatctggcag ctcccagatt cagagttccc cgcaaaactg
    11281 ctgtgaaata ctttttctct tcctcagtag tcggtcccat gacaacagta cgggtaatat
    11341 cagtagttcc ctctttataa tgtcctcctg tatctgccag aagaaagccg gatggttcca
    11401 gaggaatatc cgtttcgggt gttgcaaaat aatgtacaat agcagcatgc tttccatagg
    11461 caataatcgg atcaaaactg ttatctatga aatcctcctg ttccaaacgg aattcataca
    11521 gcttttctgc tgcacttaat tctgtgatcg gaatccttcc aacattcttc tttaaccagt
    11581 atatgaactt tgtaactgca actccgtctc tgatatgcgc aatgcgttca ttttccacct
    11641 caacaggatt cttcgttgcc ttgggaagaa gtgtaagatt ttcttcatcc agaatccggg
    11701 tgtctgccgg aatattgcta accagacgac tgttgacttt ctttttgcag agaagaactt
    11761 ttttgtcctt tttaaatgtt ttcacatact catagatact gtcataggga aaaagggtca
    11821 caccatcttt ttccagcgct tccagtacgt ctgtctgaaa ggctttctca tttgcaaaaa
    11881 gtctgatctc tgtttttgtc attacaagat aagaaagaac caccggacaa cagtggatat
    11941 ctcccccacg tatatttaac agccaggcaa tatcatccag agaagtcagt acaaataaat
    12001 ctgcaccctt cttctccatt gctttgcgga ttcttgcgca tttatcagct ctggattctc
    12061 ctgcccattt tatatccagc tctgtaaccg gttcacagga aagtaccgga cggttttccc
    12121 atatatcccc tgccagatcg tgatcaacgc tgagagacac accgttttca tccagcattt
    12181 tctccagttc tgatgcctct tttgagctga cagtacgtcc gtcaaatccc agacacattc
    12241 cctgtgtcag attttttttc agaaattcat gaactgtggg aacttccggc tcacccattt
    12301 taaataaagt aattcctgtt ccctccagct gatctgcagc ctggataaaa taacgtccat
    12361 ccgtccataa tcctgccata tcctgcatga tcaccgcagt gcctgcagaa ccggtaaatc
    12421 ctgtgatata ttttctgcat ttgaaatatt cacctacata ttctgaacca tgaaaatcat
    12481 ctgtaggaat cagatatgca tcaattcctg tctctttcat gcgtgcacga agtgctgtta
    12541 ttctctcttt tactgtcatt cgtttttacc cttaaggctg ctatctgcag tcgttttatc
    12601 attttcgcca agtgtttcgt tcatacttcc catacgatat cccagaatat ccatggtcac
    12661 ataagtgaat ccatactcct taaatttctt cacaatatcc tctcggacat ttttttccag
    12721 aagtttcgga aattcctccg gcatgatctc aattcttgca agtgaaccgt gaatacggac
    12781 acgtacctga tggaatccat agtcaagtaa aagctgctct gctttctcaa ccattccaag
    12841 cttttcctca ctgatggtct ctccatagac aaacctggag gacagacagg caaatgactg
    12901 tttgtcccag gtcggaagcc ccagttcctt tgagtattct ctgatctccg ctttcgtcag
    12961 cttcgcctca cgtagcgggc tcttaactcc aagttctttt acggcgatca gacctggtct
    13021 gtaatcgcca ttatcatcca tatttgatcc ctctgcaata tattcaatcc cattcttttt
    13081 tgcaatatcg ccaatcttct caaacagttc ttttttacat aaataacatc tgttcggagg
    13141 attctttgaa aatccttcaa tctccaattc ctcagactgg cagatcacat gctgaatccc
    13201 ctctttctcg cagaatgcct tcgcttcatt cagctctctt ttcgggaaag aacaggattg
    13261 agctgtaatc gcaatcgcct tatcacccag cacatcatga gctactttta ataagaatgt
    13321 agaatccact ccacttgaga aagcaactgc tacactgcca agtcccttca gatattcttt
    13381 taaatgttcc agtttatttt ccatatcagt ctgcctcttg tccgtttttt attgtacctg
    13441 tagcactcct cgtaaataat gtatattgat ctggctcaac aaagcgtgaa agttgaactt
    13501 tctcaaatgt attatttaac agggtgctat agcttcatta taatataggc aatgactgtt
    13561 cagcaactta tttttcgcat tgcgaaatgt gttactgaaa atagaacgaa caatattgat
    13621 ttatgtttct tgtatctttt ctaacgcttc cccgacttct gttacttctt taaatagttt
    13681 ctaaagtaac agcctctctt aacttcttta tttacagttt gtctacttct ttttctgaag
    13741 cagttctccg tttgtttctt ccccattcat acatgacata ataattagcc actaccccat
    13801 attataaata acacccagag atacttattt cagactgata atcagatttt tattgaattt
    13861 attaatctat atgttatgac aacatatc
//
