LOCUS       c00145_gnlPro..        12992 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGPGBIAA_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:41:12
            Original ID  :: gnl|Prokka|AGPGBIAA_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12992
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1374
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_1"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.6e-46, bitscore:
                     148.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ISEQVSVPLEVFVHGALCVSYSGQCYLSAALSGRSANRGECAQYC
                     RLPYSMVDANGTEIVHNKHLLSLKDMNRSDQLEALLDAGASSFKIEGRLKDVTYVKNIT
                     AYYRKKLDAILTRRPEYIRASAGKSTYEFEPVAEKSFNRGFTPFFLHERTKDITAFNTP
                     KSLGEPVGTVKELKGNSFTIAGVKQLNNGDGLVFFNSRGELEGFRVNRVEANRVFPLDM
                     PDIKPKTPLYRNFDQVFEKQLAKPSAERKLAVRIEFLDNPFGFTLVMEDETGARVMLTE
                     PFDKELARRDQADNIRTQLAKLGNTPFEASEVHIGMGENWFVPSSLLADMRRKAVEKLQ
                     SDRMIRYQRELSRKVEPAKEVPFPERQLTYLGNVSNSRAEAFYKAHGVETVAEAFELKP
                     EKDVPLMFTKHCLRYSMGWCPTYQKEKSPYKEPYYLLYKDTRLRLQFDCKRCQMLVYK"
     protocluster    1..12992
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8197:12990]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8198..12990
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12992
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12992
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             1922..2632
                     /locus_tag="ctg145_2"
                     /transl_table=11
                     /translation="MGDVTVLLYDDTPLHRDNFIRLCRSGEYEGMLFHRIIKDFVVQGG
                     DPTSKAHEPGVLYGDGDGGYTVPAEILPNHFNKRGALIDAKESDDVNPERASAGTQFCF
                     VQGKKHTDAELDEKEVRINQIRRNWLYYKFLDQLKKEDPALAADSLETELTNRALVMVE
                     DTLADLGPYVIPAEHREVYKTVGGVPHLDSSVTIFGEVVDGFDIVEKMSLVKTDKNDRP
                     IQDVMIKSTKVFQK"
     CDS             2702..3352
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_3"
                     /sec_met_domain="Epimerase (E-value: 9.2e-13, bitscore:
                     37.9, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVIIGATGYVGSAILKEALGRGHQVKAIVRDPSKLTLIHPHL
                     KVVGGNVTDTDFLSRELAKSDAVISAFNPGWSNPNIYEETLEGYGSILCAVRNSGVHRF
                     LMVGGAGSLLVAPGRQLMDEPDVPKKLLPGIRGMAKVYTDLLLPEKSVDWVFLSPAANM
                     APGERTGKFRLGKDELIVDESGDSNISVEDFAVAMIDELEQEKHHQERFTLGY"
     CDS             3463..4089
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_4"
                     /sec_met_domain="HAD_2 (E-value: 3.1e-09, bitscore: 27.0,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKNIVFDLGGVFIDLDHDQAVRRFKEIGVEDAEQLLDPYEQK
                     GIFLEVENGTISADEFCQKLREHTGKDLTYEDIKSGWLGFIVDTPQYKLDYVLKLRERY
                     NVYLLSNTNPIIQEGWARTNEFTSAGRPIGAYFDKMYTSYEVGVTKPDRRIFDYMIKDS
                     GLIPAETLFVDDGKSNIEVGRTLGFITYQPQNGEDWREAIDALLK"
     CDS             complement(4105..6462)
                     /locus_tag="ctg145_5"
                     /transl_table=11
                     /translation="MNKRLKSNESLANYQYLMDTIWTIYLEDGSVEIQKDSMIPELENT
                     KHDYVILNNTIKNDVYLPDHTLWDETVSLEAFRKMIAEGCFHKKFDMRFCNDHFGFEWH
                     EAFIDILTNKEGIPDRVVFSSHNVNDFRKSQIIETAVKAEYDYVIYIEASKNSYVMYTS
                     GTESETPPPVASSNYEAVVAEYNRQYMEPEFCDTMTEKMSIAHVDPILRQHGEYILYGT
                     MIENGENREKKIRFSNFDREQNIWLMTRTDITEIKEERKQKLLLQEAPQSATAANRAKS
                     DFLSRMSHDVRTPINAIVGMTAIAGLHMNDQNRIADCLKKITISSKLLLNLINEVLDMS
                     KLESGKIMLTEETFKLDELLESLFIMVQSAFEAKKQKLVIHSKVKHECLIGDVQRIQQA
                     LLNMLTNAIKYTPDKGLIQISVEEKPSVYNGYGQFEIAVTDNGIGMKPEFLSKVFEPFE
                     RSDDKAIRNIQGTGLGMAISRHIAQMMNGDILVESEYGKGSKFTMRFHVKLGGMDEYDN
                     NLLIDLPVLVVDDDDVSCEIAYENLQELGMKPEWVLSGQDAVQKVNEGNNYFAIIIDLM
                     MPNMNGIETTYKIRECVGPDIPIIIISAYDYSGYEIEALKAGVNGFICKPIMKSKLFHL
                     MKKFATNKKEEEQATVVPSIVSSFPDKRILVVEDNDLNREIAYELLQETGAEIETASDG
                     LEAVNKVSASPEGYYDFIIMDIQMPVMDGLEATRQIRLLNRQDIKDLPIVAMSANAFAE
                     DVRLSLEAGMNEHIAKPIEIDRLYSVMGKWFR"
     CDS             complement(6475..6837)
                     /locus_tag="ctg145_6"
                     /transl_table=11
                     /translation="MTSEYKEKLQAYGVNLDSALNRFMDNEQFYERILSKFPMDENFIL
                     MERSLNENNISLAFRYAHTLKGLVATLDLTNISDILIPMTEKLRTGDTEGMQDLFDQLK
                     VQYKLICDLITEHKAR"
     CDS             complement(7136..8176)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 5.9e-50, bitscore:
                     160.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYDVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIKLDLKDKEGTREALKAHPGINGIILFAASKAVGESVQQPLKYYRNNV
                     VTLVNLLELMPEFNIEGIVFSSSCTVYGQPDPENLPVTEDAPIKPATSPYGNTKQINEE
                     IIRDTIHANAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAIGIRKELSV
                     FGDDYDTPDGSCIRDYINVVDLAKAHVIAMDRMLGGKTEENVEYFNLGTGNGVTVLELI
                     NTFEKATGVKVPHKIVGRREGDIEKVWANPERANKVLGWTAKETLSDTLASAWKWQEKL
                     RERGIQ"
     CDS             complement(8198..8770)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 3e-66, bitscore: 212.5,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDKFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALVIFAGIREQLALTRVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             complement(8789..9373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQMCMEAFVPTLYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGLGMGLGFTLALTLLGATRELLGTGKLFGLTLMP
                     EQYGSLIFVLAPGAFIALGYLIAIVNKLRKA"
     CDS             complement(9366..9971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_10"
                     /sec_met_domain="FMN_bind (E-value: 2e-25, bitscore: 79.1,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FDNKPSEDAYMAVTADGDSLKIYPASKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSAGPLKVTKDGGDVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             complement(10004..10963)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_11"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.7e-120,
                     bitscore: 390.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVVACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLLGKMGGSLGEVSALALLLGLVFMLWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(10976..12307)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_12"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.6e-17, bitscore: 53.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.9e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.2e-32, bitscore: 101.0,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVANPSNFLVRMGTPISALIEAAGGIPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             complement(12319..12990)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.1; E-value:
                     1.2e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_13"
                     /sec_met_domain="Fer4_7 (E-value: 2.6e-12, bitscore: 37.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.4e-12, bitscore: 35.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7e-10, bitscore: 28.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.2e-07, bitscore: 19.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TNQYDGVQSCAIASTLYGGETGCSFGCLGYGDCVAACNFDAIHIN
                     LETGLPEVDEDKCTSCGACVKACPKNIIELRKKGPKSRRVFVSCVNKDKGGVAKKACAN
                     ACIGCGKCAKECPFEAITVENNVAYIDYTKCRLCRKCVAVCPTGAIHELNFPPRKEAAP
                     AVDADKIKPATAPKPAAPKADAPKTEAPKKESPKAEAPTANATPNAETPKIETKEETIQ
                     K"
ORIGIN
        1 atatcggaac aggtttctgt cccgctggag gttttcgtac atggcgcatt atgtgtgagt
       61 tacagcgggc agtgctatct gagtgcggct ttgagcgggc ggagcgctaa cagaggagag
      121 tgtgcgcaat attgccggtt gccttattcg atggtggatg cgaatgggac ggagatcgtt
      181 cataacaaac atttgttatc actcaaggat atgaaccgtt ccgaccaact ggaagccctg
      241 ctggatgcgg gtgcttcttc ttttaaaata gaagggcgct tgaaagatgt cacttatgta
      301 aagaatataa cggcttatta ccggaagaaa ctggatgcta tattgacgcg ccgacccgaa
      361 tatatccgtg cctcagcagg aaaaagtacc tatgagtttg agccggtagc cgagaaaagt
      421 ttcaaccggg gatttactcc tttcttcctg catgaacgta caaaagatat aacagctttc
      481 aatactccga aatcattggg tgaacctgtc ggaaccgtca aggaactgaa aggcaattcg
      541 tttaccatcg ctggagtgaa gcaactgaat aatggggatg gcttggtatt tttcaatagt
      601 cgcggtgagt tggaagggtt tcgtgtcaac agggtagagg cgaaccgtgt ctttccgttg
      661 gatatgccgg atataaagcc taagacgcct ttgtatcgta actttgacca ggtttttgaa
      721 aagcagttgg cgaaaccttc tgccgaacgt aagctggctg taaggattga attcctggat
      781 aatcctttcg gttttacatt ggttatggaa gatgaaacgg gagcacgtgt gatgctgacc
      841 gagccgttcg ataaggaact ggcacgccgt gaccaggccg acaatatccg gacgcaactt
      901 gccaagttgg ggaacacgcc gtttgaagct tcggaagtac atataggaat gggggaaaac
      961 tggttcgttc cgtcgtctct tctggcggat atgcgtcgca aggctgtaga gaagttgcag
     1021 tcagaccgta tgatccgtta ccagcgtgaa ctctcgcgta aggttgaacc tgcgaaagag
     1081 gttccttttc cggaacgcca gttgacttat ctggggaatg tctctaacag ccgggcggaa
     1141 gctttttata aggcgcatgg ggtagagaca gttgctgaag cctttgagtt gaagccggaa
     1201 aaagacgttc cgttgatgtt tacgaagcat tgcctgcggt atagcatggg ctggtgcccg
     1261 acgtatcaga aggagaagtc accttataag gaaccttatt atcttttata taaggatacc
     1321 cggctaagat tgcagttcga ttgtaagcgg tgtcagatgc tggtgtataa atgatttttt
     1381 gaaattaact atcatactat cactttctga tataagatgt tgtaactatg attgttatat
     1441 tgtgatagta ggggttttca actatcactt atctatcatt catctatcat accctgctta
     1501 aaaagtagta tagacagtat gctgttttta gtgactatat agctaaagtt cagcaagata
     1561 ataataagag ttgctctaca cccgggtctc taccccctct acacccggat gtaggcatcg
     1621 ttaagatggg ggtgtaaaac aggatgagat gggcatcccg gcaacaaaaa gtctgtattc
     1681 gggtgaaatg aagtaataga tttgggataa aaaggtagta aggaaacgaa ttataagaga
     1741 ccgtatacag cagggcggaa aggatacttg catatctgtc aataatgaac aaataaataa
     1801 aaacaaggtg ttatgaaaca acgactattt actcttttgc ttcttctttt ttactttggt
     1861 ctcttgtggc gataaaccgc tggacccttc gaaacccgtt tatgtgacag tgaaaacgac
     1921 tatgggagat gttactgtcc tgttgtatga tgacactccc ttgcatcgtg ataacttcat
     1981 ccggttgtgc cggtcgggtg aatatgaggg gatgctattt caccgtatca ttaaagattt
     2041 tgtagtgcaa ggtggtgatc cgaccagcaa agctcatgaa ccgggtgttt tgtatggaga
     2101 cggtgatggt ggttataccg ttccggccga gatacttccc aaccatttca ataaacgagg
     2161 tgctctgatc gatgccaagg aaagtgatga tgtaaatccc gaacgtgcat cggccggaac
     2221 ccagttttgt ttcgtgcagg gaaagaaaca tactgatgct gaactggatg agaaagaggt
     2281 acggatcaac cagattcgcc gtaactggtt atattataaa ttcctggatc agttgaagaa
     2341 agaagatccg gcactggctg ccgactcttt ggaaacggaa ctgacaaacc gtgctttggt
     2401 tatggtggag gatacattgg ccgacctggg cccgtatgtt attcccgccg aacatcgcga
     2461 agtatataag acggttggcg gagtgcccca tctggatagt tccgtgacga tcttcggaga
     2521 agtggtggac ggtttcgata tcgtagagaa aatgtcgctg gtgaaaacag acaagaatga
     2581 ccggcctatc caggatgtta tgattaaatc gacgaaagta tttcaaaagt aaattcgctt
     2641 ttccaaaaca agatggctac ctgatgttgt tctatagaaa gtaatcaaac aacatacagt
     2701 catgaagaaa atagttatca taggcgcgac cggctatgtc gggtccgcta ttctgaaaga
     2761 agcattaggc agggggcatc aggtaaaagc catcgtcaga gatccgtcga aactgacttt
     2821 aatccatccg catctgaaag tagtgggagg gaatgtgacc gatacggact ttttatcccg
     2881 cgaactggct aagtcggatg cggtgatcag tgctttcaat ccgggctggt cgaatcccaa
     2941 tatttatgaa gagacactgg aaggctatgg ctctatcctt tgtgccgttc gcaactccgg
     3001 tgtgcatcgt ttcctgatgg ttggcggagc aggcagtttg ttggtggctc ccggtcgtca
     3061 gctgatggat gaaccggacg ttcccaagaa acttttaccg ggaatacggg ggatggcaaa
     3121 ggtttatacc gatttgttgt tgccggaaaa gtcggtggat tgggttttcc tgagtcctgc
     3181 ggctaatatg gcaccgggag agcgtaccgg aaagttccgt ctgggaaaag atgaactgat
     3241 tgtcgatgaa agtggggata gcaacatctc cgtagaagat ttcgctgttg ccatgattga
     3301 tgaactggaa caggaaaaac atcatcagga gcgatttaca ctcgggtact aagtgtcttt
     3361 gacaaaaaca gttgcaggta ttcgaatagt tgttgcttta cacttattat gcttatcttt
     3421 gtcaggaagt agagataaag atagatgtaa aaagagataa ttatggcaaa gattaaaaac
     3481 attgtatttg atttaggagg agtttttata gacctggacc atgatcaggc agttcgtcgc
     3541 tttaaagaga tcggagtgga ggatgcggaa cagttgctgg atccttatga gcagaaaggg
     3601 atctttctgg aagtggaaaa cggtacgatc agtgctgacg agttttgcca aaagcttcgg
     3661 gagcatacgg ggaaagacct gacgtatgaa gatataaaat ccggttggct gggatttatc
     3721 gttgatacgc ctcaatataa gctcgattat gtgttgaaac ttcgcgagcg ctacaatgtt
     3781 tatctgttga gcaataccaa tcccatcatc caggaagggt gggcaaggac aaacgagttt
     3841 acttcggcag gtcgtccgat cggtgcctat tttgataaaa tgtacacctc gtatgaagtt
     3901 ggcgtaacta agcccgaccg gcggatcttt gactatatga tcaaagacag cggactgatt
     3961 ccggcagaga cgctctttgt ggatgatggt aaaagcaata ttgaagtagg acgcacactg
     4021 ggcttcatca cctaccaacc ccaaaacggg gaagattggc gtgaagctat cgatgcactg
     4081 ttgaaataaa ccggttgggg gtattcaacg gaaccacttt cccataacac tgtaaagcct
     4141 gtctatttct atgggtttgg cgatatgttc gttcatcccg gcttccaggc ttagccgtac
     4201 gtcttcggca aaagcattgg ccgacatggc tacgatcggt aagtccttga tgtcttgccg
     4261 gttgagaaga cggatttgcc gagtggcttc aagaccgtcc atgacaggca tttgtatatc
     4321 catgattatg aaatcgtaat atccttcggg ggaagcggaa accttgttga ctgcttccag
     4381 tccgtcgctg gctgtttcaa tttcagcacc ggtttcctgt agcaactcat aagcgatctc
     4441 acggttcagg tcgttgtctt ccacaacgag tatccgtttg tccggaaaag aggagacgat
     4501 agatggtacg acagttgcct gttcttcctc ttttttgttt gtggcaaact ttttcatcag
     4561 gtgaaacagt ttggacttca tgataggctt acagatgaaa ccgttgactc ctgctttcag
     4621 ggcttcgatt tcgtagccgg aatagtcgta agccgaaatg atgataatag gaatatccgg
     4681 tcctacgcat tcccgtattt tgtaggttgt ttcaatgcca ttcatattgg gcatcatcaa
     4741 gtctatgatg attgcaaaat aattgtttcc ttcgtttact ttctgtaccg catcctgacc
     4801 ggaaagaacc cattccggtt tcattcctaa ttcttgcagg ttttcatagg ctatttcgca
     4861 ggatacatca tcatcatcca caactaatac cggcaggtct attaatagat tgttgtcgta
     4921 ttcatccatg cctcccagtt tgacatggaa tctcatggtg aatttggaac cttttccata
     4981 ttcgctttct accaggatat ccccgttcat catctgagcg atatgacgac tgattgccat
     5041 accgagtcca gtcccctgga tattgcggat ggctttatcg tccgaccgtt cgaacggctc
     5101 gaatactttg cttaagaatt caggtttcat tcctatgcca ttgtccgtga cggctatttc
     5161 aaattgcccg taaccgttat aaacggaagg tttctcctcg actgaaattt gtattagtcc
     5221 tttgtcaggg gtatatttga ttgcatttgt cagcatattc aacagtgcct gttgtatgcg
     5281 ttgtacgtca ccgatcaggc attcgtgctt tactttgctg tgtattacta acttttgctt
     5341 ttttgcttca aaggccgact gcaccatgat gaataaactt tccagcagtt cgtcgagttt
     5401 gaatgtctct tccgtcagca tgatcttacc gctttcgagc ttcgacatat ccaatacttc
     5461 gtttatcagg ttgagcagga gtttggaaga tatggttatt ttcttcaggc agtcggctat
     5521 gcggttctgg tcgttcatat gaaggccggc tattgccgtc atgcccacga ttgcatttat
     5581 gggagtacgt acgtcatggc tcattcgtga caggaagtct gacttggcac ggttggcggc
     5641 tgttgcgctc tgtggggctt cctgcaacaa tagcttctgt tttctctctt ccttgatttc
     5701 agttatatcg gtcctggtca tcaaccagat gttttgttcc ctgtcgaagt tgctgaaccg
     5761 tattttcttt tcacggtttt caccgttttc tatcatggta ccgtataaaa tatactctcc
     5821 atgttgtcgc agtatcggat cgacgtgggc gatactcatc ttctcggtca ttgtgtcgca
     5881 aaactccggc tccatatatt gccggttgta ctctgcaact accgcttcat agttgctgct
     5941 ggctaccggg ggaggagttt cgctttccgt accggaagtg tacatgacat aactgttttt
     6001 agaggcttcg atataaatca catagtcgta ttcagctttc acggctgttt caatgatttg
     6061 tgatttcctg aaatcattaa cattgtggct ggagaagaca accctgtcgg gtatgccttc
     6121 tttgttagtc aagatatcta taaaggcttc gtgccattca aaaccgaaat ggtcgttaca
     6181 gaaacgcatg tcgaattttt tgtggaaaca tccttcggct atcattttac ggaaggcttc
     6241 aagcgaaacc gtttcgtccc atagagtatg gtcaggcaga tagacatcat tctttatcgt
     6301 gttattgaga atgacgtaat catgtttcgt attttccaac tccggaatca tggagtcttt
     6361 ttgtatttcg acacttccat cttccagata gatagtccag atagtatcca tgagatattg
     6421 gtagttagcc aatgattcat ttgatttaag cctcttattc atgcagtttg tttattatct
     6481 tgctttgtgt tcggtaatca ggtcgcagat tagtttgtac tgtactttca gctgatcaaa
     6541 caggtcttgc ataccttcag tatctccggt tctgagtttt tctgtcatcg ggatcaatat
     6601 gtccgatata tttgtcaggt caagcgtagc caccagtcct tttaatgtat gggcatatct
     6661 gaaagccagg gaaatgttat tctcattgag gcttctttcc atcaggatga agttttcatc
     6721 catagggaat ttggaaagta ttctttcata aaactgttca ttatccatga aacggtttaa
     6781 tgcactgtcc aggttaactc cgtacgcttg taacttctct ttatattcgc ttgtcatgtt
     6841 ttttatcacc atttatataa caaatcatct gtctgttacg aaaggaatcc ccaaaagtag
     6901 ataaaaaata tgtatggaga tggaaaaagc gttataattc aataggaatg tatgtttttt
     6961 tctgctaatt gacgaatcca gtcctccaac gagtctgttt tgatgtctga tgttggtttt
     7021 gaagctcagt caacgtttca ttgataagta ccggttacat gcaggggggc aagaaaaatg
     7081 ccggaagaaa tctctggaga atcttccggc atgcttattt aaaaagactt ttcttttatt
     7141 ggataccgcg ttcgcgcagt ttttcctgcc atttccaggc agaagccaaa gtgtcggaca
     7201 acgtttcttt agcagtccag cccaatactt tgttggcacg ttccgggtta gcccaaactt
     7261 tttcgatatc accttcgcgg cggcctacga ttttgtgagg aacttttaca ccggtagctt
     7321 tttcgaatgt attgatcagt tccaacactg ttacaccatt accggttccc aggttgaaat
     7381 attcaacatt ctcttctgtt ttaccaccca gcatacggtc catagcgatt acgtgtgctt
     7441 ttgccaggtc gactacattg atatagtcgc ggatacaaga gccgtcaggt gtatcatagt
     7501 cgtcaccgaa tacgctcagt tccttgcgga taccgattgc agtctgtgtc agatacggga
     7561 tcaggttctg gggaacgccg ttaggcaatt cgccgatttc tgcactcggg tgagcaccga
     7621 tcgggttgaa gtaacgcagg ataatgctct tgaacggagc gtttgcgtga atagtatcgc
     7681 ggatgatctc ttcgttgatc tgtttggtgt tgccataagg agatgttgcc ggtttgatcg
     7741 gggcatcttc tgttacaggc aggttttcgg gatcaggctg tccgtaaacg gtacaggaag
     7801 aagagaatac gattccttcg atattaaatt ccggcatcag ttccagcagg tttaccagcg
     7861 taacaacatt gttacggtag tacttcagtg gctgctgaac cgattcgcca acagctttgc
     7921 ttgctgcgaa aaggatgata ccattgatac ccggatgagc cttcagtgct tcgcgggttc
     7981 cttctttatc ttttaaatcc agtttgatga attcaggacg gatacctgtg atcttttcaa
     8041 tgccatccaa cacttcaata ttggagtttg acaggtcgtc gatgataact acatcataac
     8101 ctgcattctg caactcaact gtagtgtgtg agccaatata tccggttcca cctgctacta
     8161 agattttctt tttcatgcta gtctctattt agattaatta tacgattccg gagaatccca
     8221 taaacgccat tgccagcaaa ccggctgtta tcagcgcaat aggggtacct ttcatacctt
     8281 cgggaacacg tgtcaaagcc aactgttctc ttatccctgc aaagataact aaagctagcg
     8341 caaatccaat agctgttgat attgcatata caacagattc caataaatta tattcttttt
     8401 gtattacgag gatggcgaca cccaggatac agcagttggt ggtaatcaac ggaaggaaca
     8461 cgccaagtgc ctggtaaaga gccggagaaa cctttttcag tatgatctcg accatctgaa
     8521 ccagtgcggc gatgatcagg ataaagctga tggtctgcat aaagcccaat ccgaacttat
     8581 ccaggatata tttctgcacc aggaaagtaa cgatggttgc gatcgtcaac acgaatgtta
     8641 ctgctgcacc cataccggct gccgtttcca ccttcttcga tacgcccagg aacggacaga
     8701 tacccaggaa ctgcgccaac actacgttgt tgacgaatac ggctgcgata aatattagta
     8761 tatattccat atctttcgtt ttttaatatc aggctttacg caatttatta acaatagcaa
     8821 tcaggtaacc cagcgcgatg aaggctcctg gtgccaatac aaagatcagc gaaccatatt
     8881 gttcgggcat cagtgtcagg ccgaacagtt tacctgttcc caacagttcg cgggttgctc
     8941 ccagcaaggt aagtgccagc gtaaagccga gtcccatacc taatccgtcg aatgcggaag
     9001 ggatcactcc gtttttagcg gcaaatgctt ccgcacgtcc caacacaata cagtttacaa
     9061 cgatcaacgg gatgaacaat cccaggctgg cgtaaagagt cggaacgaat gcttccatac
     9121 acatctgcac gacggttacg aatgtagcga ttacgacaat aaaggccgga atacgtacca
     9181 tgtcggggat caggttcttc aaggctgaaa taaccatatt ggaacagatc aaaacgaaca
     9241 tggtggccag tcccatactc ataccgttca gtgctgaaga tgttgttccc agagttggac
     9301 acatacccag caacaagaca aatgtcgggt tctctttgat gataccgttc atcaatactt
     9361 tcatattact cattgtcgtt tcctccctcg ttagtgttag cggttgttgc accggttact
     9421 ccgtcagttc cggcgaatgc gctgtaagca cggttcaccg catccagaaa tgcacggctg
     9481 gtgatggttg ctgctgtgat agcatccacg tcgccaccgt ctttagttac ttttaatggt
     9541 ccggcggaga ggctgcgccc cagcacgctt tgtttattct tgtccgtact gaaccattcc
     9601 tgcatcttag ctcccaagcc gggagtttct gcatgttgta atacggaata attcaataac
     9661 ttgccttcct tatcgaatcc gacgattact ttgatctcgc cgctgaatcc tttctttgta
     9721 ttactttcga cagctgcacc tacgaactct ccgcctttgg aagccggata gattttcagg
     9781 gaatcgccgt cggccgtaac tgccatataa gcatcctccg acggtttgtt gtcgaattca
     9841 ggtgttacag ctttgatagc agcttccagc gctgcagctt tagaggctgc tatcgggccg
     9901 gtggtgtaca tatttactcc ggctaatatc gctcccgcaa ccaaacagat gatggtaagc
     9961 gacaagagca tattgggtaa tgttgatttt agttttgcca tgcttatttc cctccaaaat
    10021 gtttaggttt gatataactg ttgatcagcg gggtaaatgc attcataata agaatagcaa
    10081 acgacatacc ttccggataa gaaccaaaca gacggataac ggtggttaga ataccgatac
    10141 cgacaccgta gaccagcata ccgttcttgc tcatgggcga agtcacatag tcggttgcca
    10201 taaagatggc tcccagcatc agacctcccg acagcaggtg aacgaacgga cttgcgtatt
    10261 gtaccggatt aaccaggtgc ataataccag tgaatacaaa tacggtcagc aggatagaaa
    10321 ccggaatctg ccaggtaata atctttttcc ataacataaa gacaagtccc agcaacaatg
    10381 ccagtgcact tacttcaccg aggctaccac ccattttacc taacaacata tctaccaggg
    10441 taggtaactt gtcgagtgct ccttcattca tcagtgataa aacagttgca ccggtggttg
    10501 cgtcggtgta ggctgtcagc tgcccgactt ccggccacat cgtcatctgt gccgggaaag
    10561 agatcagcag gaatacacgt ccgaccaatg ccgggttaaa gatattgtta cccagtccgc
    10621 caaacgacat cttgccgata ccgattgccg ccaatgcacc gatcaggatg atccatacag
    10681 gcaggttcga cggcaggttg aatgccagca gtacaccggt caggatagcc gaaccgtcac
    10741 atacggtcgg ttcctttttc atcaggaact tctggatcag atattcaaag aggacgcagg
    10801 ctacgaccga tgttgcagta acgatcagcg cacccagtcc aaagtagtag agggatacca
    10861 ggaaagccgg aacaagggca atcagtacac catacatatt tttgcttatg ctatcgccgc
    10921 cgtggatatg gggcgaagga gatactatta aattattttc catattgctc tgtttttatg
    10981 actttcgtgc ccgtatgata cccattacct ttcctttacc cgaacggata taatccagta
    11041 acggacggtt ggccgggcag gtataactac aagaaccgca ctcgatacag tcggtgatat
    11101 aattcttctc ggccaaatcc cattctgcaa attctgttgc attcatcagc agggtagggt
    11161 tgaggcccat cggacaaacg ctgacacatt tggcacagcg gatacagtcg cgcatcggtt
    11221 tgcggacaga ctcttctttc gtcaggagca atacgcctga actacctttc gttaccggta
    11281 cttccggagc aatcagggct tttcccatca tcgggccacc accgattatc tttcctgtat
    11341 tttcaggaat gccaccggct gcttcaatca gtgcactgat tggtgtaccc atacggacca
    11401 ggaagttgga aggattggct accgctttac ctgtcacggt aacgacgcgt tcaaacaaag
    11461 gtttgttttt cattaccgct tcatacactg caaaagccgt tcctacattt tgtactacag
    11521 ctccggcgga aataggcagt gcaccgctct tcacctgacg gcgaatcaca gcgtcgatta
    11581 attgcttttc acctccttgc ggatattgta ctttcagcgg cataatctcg atacctttat
    11641 aggctgtagc tagtttactc agatgagcga tggcgtcggg cttgttgttt tcgataccga
    11701 tcacagcttt tgttacattt acagctttca tcaacagcgt aacgccgacc agaatctgct
    11761 ctgccttctc catcatcaac gaatggtcgg aagtcagata cggctcacat tctacagcgt
    11821 tgataatgat gatctcggct ttgcttccgg gaggtggcat cagtttgacc tgtgtgggga
    11881 atgtcgcacc acccagaccg acgataccgg ctgcagcgat cttgtctacg atttctttgg
    11941 aaggaagcgg acactctttc acgagcgttt cgctgcggtc gatcgactct tcccattcgt
    12001 caccttccac atcaatatag atagcgggac gtttgtatcc gcttgcgtcg agagcgttat
    12061 ctatcttgtt tactttaccg gataccgacg agtggatatt cgccgataca aaacctccgg
    12121 ctttggcgag aagtgtacct actttaactg tatcaccctt ctttaccaca gcctgggcag
    12181 gagccccgat atgctggctc agcggtataa taacctgctt gggtatagcc agtccggtga
    12241 ttttcttccc ggcagacaat ttattttcgg gtggatgtat acctccgatt cgaaatgtcc
    12301 ttagcatact attagatttt atttttgaat tgtttcttct tttgtttcaa ttttaggagt
    12361 ttctgcattt ggcgtagcgt ttgctgttgg agcttctgcc tttggagact ctttcttcgg
    12421 ggcttcagtc tttggcgcat cagccttcgg agcggctggt ttcggagctg ttgccggttt
    12481 tattttgtcg gcgtccacag ccggagctgc ctctttacgt ggcgggaagt tcaattcgtg
    12541 gatggcgccg gtcggacata cggctacgca cttgcggcat aagcgacatt ttgtgtaatc
    12601 gatgtaggcc acgttgtttt ccactgtaat tgcttcgaac gggcattcct ttgcacattt
    12661 gccacagccg atacaagcgt tggcgcatgc tttcttggct actccgcctt tgtctttgtt
    12721 tacgcagctg acgaagacgc ggcgtgattt ggggcccttc ttacgcagtt cgatgatgtt
    12781 tttcgggcaa gcttttacgc aagctccgca tgaagtacat ttgtcttcgt ccacttccgg
    12841 aagcccggtc tcaaggttga tgtggatggc gtcgaagtta catgcagcca cacagtcgcc
    12901 ataacctaag caaccgaatg aacagccggt ctctccgccg tacaaggtgg aagcaatcgc
    12961 acaactctgc acaccgtcgt attggttggt ac
//
