LOCUS       c00405_gnlPro..         5038 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGPGBIAA_405.
ACCESSION   c00405_gnlPro..
VERSION     c00405_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:41:12
            Original ID  :: gnl|Prokka|AGPGBIAA_405
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5038
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5038
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[784:4914]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      785..4914
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5038
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5038
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(17..748)
                     /locus_tag="ctg405_1"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEISPD
                     KYNMSICHDGKAISRAAVTWI"
     CDS             complement(785..1339)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.5e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLREKHV"
     CDS             complement(1352..3052)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVNYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELHPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(3079..4914)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_4"
                     /sec_met_domain="ILVD_EDD (E-value: 1.9e-218, bitscore:
                     714.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELTKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 atttgtctct actttgttat atccaggtaa cggcggcgcg gctgatagct ttgccgtcgt
       61 gacaaatgga catgttgtat ttgtccgggg atatctcctg gttatggaga gtcagctcca
      121 tcccatactt tccttcggac tgataagcta tttcgaaacg gcttatctct ttttcgcgga
      181 acaggctgat atcgaacaag tcgagcaggt gttccatata tttgatactg ttcaggtggc
      241 cgtttacgtc caagtcactg tacttcacac ggtaaggttc accggaggtg ttgttttcca
      301 ccggagcgat tttacccggt ttttcaatcg gacagggacg gtcggtgata taagcactca
      361 ggccctccac atcgagcaag gtcgggcgac gggtttccat atcgatagcc gcccagatag
      421 agcgggcaaa accaaaggtc ttgccttcac cgttcaccag ttcgaagcag cggctggtaa
      481 ataacttacc gacctcatcc acccaggtat ataaagttac ggattcagac atggcaggat
      541 aagaagtcat ctcgatagcc agacgggaaa gaacccaggc ggtatgcctt tcggtcatat
      601 cgttatatcc gaatccacgg tcggcggcat ggcaagaagc agcatgcaac aaatatgtgc
      661 cgatcatagg gattgtgata cgtccccgga agtccatcag ataagactct gttacgaaat
      721 gaaattctcc tactttgttc ttctccataa tttattttat ttacaaaatg tttccttgtt
      781 gttctcagac atgtttttcc cgcaacttct tttccattgc agataacatg tcgctcagac
      841 gttctacctt actcttcgtt atagcaacgc gtccggaacg gataaattgc aggacaccga
      901 tcgtttcact caattcttta aacaaagcct gtgtctcatc ataatgacca ctcttttcca
      961 acaccacaca atcttcattc atttcaagga tacgggcatt gtacttacgg atcagatcct
     1021 cgaccgtccc catcttgata aagagttcgg tactcagttt ataaagggcg atttcctgat
     1081 aaaccaggtc ttcatccgta ttataatagg ctttcaggat atccacacgc ttgtcgatct
     1141 gttttacgac cttgtcgatc gtatcctcgt cggcaaaggt agtaattgta aacttatgta
     1201 ttccctttat agcagaggga gaaacagaaa gcgtctcaat gttcagttgc cggcgcgtaa
     1261 agataacagt tatctgattc agaagaccaa cagtattttc cgaaaagata ataacggtat
     1321 ataattgttt tgtattcata gtttctcctc cttacttatc acccaaaatc atgttcgtca
     1381 cgcttcctcc ggccggaacc atcggatata ccataccaca agtttccaca ttggcaacca
     1441 acatataggc accgtcgtga ttcaacattt cagcaatcgc ctcatccaag tcttcccgtt
     1501 tatctaccgc acgggaagca ataccaaaag ccttggctat cgctacaaaa tccggattct
     1561 tcatgatggt attcgaatac cgttcgttga agaacagctc ctgccactgg cgtaccattc
     1621 ccaggaaatt gttgttaaga acgatgatct ttacattcag attttcctgc atgatagttc
     1681 ctaactcctg gatagtcatc tggataccac cgtcgccggt aaagaaacag accgtacggt
     1741 caggtgctcc cagcttcgct cctatggcgg cgggaaggcc aaagcccatc gtccccagac
     1801 ctcctgaagt aactacgctg cgtgtttgtt tatatttgaa atagcgaaca cccatcatct
     1861 ggttctgacc tacatccgta accagaattg catcattatc ggttgcttcg gaaaccttac
     1921 ggactacttc gcccattttc agttggcctt cggtaggatg gagttctttt tctattacct
     1981 tattatattc ctctttttca tccggttcga attcagcatt ccattccgga cgcttccgtt
     2041 cttccagtaa agccgtaatc atcggaatcg tatgcttggc atttcccagc actttcacgt
     2101 cgaccggcac attctttccg atctccgaat tgtcaatatc caggtggata atctttgcct
     2161 gcttggcata agtcttcaga tcaccggtta cgcggtcatc gaaacgcata ccgatagcaa
     2221 tcagcacgtc acattcgttt gtcttgcggt tcggtccgac atttccatgc atccccaaca
     2281 tacctttatt taatgggaag tccgaaggta atgcagacaa gcctaatacg gtagaaccgg
     2341 ctggtatatc gtttttcaac aagaattctt tcagttcttc ttcagctcct cccaggataa
     2401 ccccctgccc aaccagacag aatggctttt tggcattatt tatcaatgaa gcagccgcct
     2461 cgatacgctc ctccctgata tccggttcag gctggtaact acgaacataa ttcactttct
     2521 gatactcata atctaccaaa cccacctgtg catctttcgc caaatccagt accacaggtc
     2581 ccggacgacc ggtcgatgca atatagaaag cacgggaaac ggcccaagct atttcttccg
     2641 ggcggcgtat ctggtaagcc catttggtaa tcggttgtgt gataccaatc acatcaactt
     2701 cttgaaaagc atctgttcca agcagtggag acggaacctg gccggcaatc accaccatcg
     2761 gcgtactgtc catcaatgca tcggcaatac ctgtgatggt attggttgcc ccgggacccg
     2821 aagtaaccac cgttactccc acttttccgg aaacacgggc atatccctgt gcagcatgtg
     2881 ttgcaccttg ttcgtggcgc accagaatat gttttaactg atctctgtaa tcgtataaac
     2941 tatcgtaaat tggtatcgcc tgcccacccg gataaccgaa gatagtatct actccttcag
     3001 cgatcagcgc tttcagcaaa gcttccgaac cggttatctt ttgtttgtcc atctctaaaa
     3061 tatagtattt ggtgtttatt aatcttctac tattcgtaca ccgcccttat cggccgaagc
     3121 aaccatcttt gcgtatgctt tcagtgcttt cgataccgta cgttggcgga aaggaggtgt
     3181 aaaggctttt gttccgcggg cttcttccgc ttcacggcgt ttggtcagtt cttcgtctgt
     3241 tacctttaca tgtatggttc tttcgggtat attaatttcg ataatatcgc cgtctttcac
     3301 taagccaatc gctccgccgg cagccgcttc gggagaaata tgtccgattg acaaacctga
     3361 tgttccaccg ctgaagcgtc cgtctgtgat tagcgcacat tctttaccca ggtgtttact
     3421 ctttatataa gaggtaggat acaacatttc ctgcatcccc ggaccaccct taggaccttc
     3481 ataggtgata acgacgacat cgccggagac gacttgatct ttcaggatac cttcgcaagc
     3541 ggcatcctgc gaatcgaata ctttggctgg accggcaaaa cggaagatac tttcgtctac
     3601 cccggctgtt ttaaccacac aaccgtcctg tgcgatattt ccatacagaa ctgccagacc
     3661 accgtctttc acataagcat gttccacatc gcggatacat ccggttgcac ggtcggtatc
     3721 cagttcttta taataacttt cctgcgatcc gagcactagg ttgaaacggt gggccggagc
     3781 acttttataa atattgattg cttcttccgt tacatttaca gaggtaatgc agtattggtc
     3841 gatagcctca ttcaaagtca gaccatccgc acgtttcacg gaaccgtcca ccagaccggc
     3901 ttttaccagc tcattcatga taccgatgat acctccggca cggttcacat cttccacatg
     3961 ataagaacaa ctcggagcca ctttgcagat aaccggtgtt ttgcgtgaaa gcatatcaat
     4021 atctttcatt gtaaaatcga cttccgcttc atgagccacg gccaacaggt gaaggactgt
     4081 attcgtcgat ccccccatgg caatatccag cgacatagca ttcaggaaag cctgccgggt
     4141 ggcaatactg cgaggcaata cggaatcatc gccgtcacga taatatttaa aggcattatc
     4201 aacaatcatc ttcgccgctt ttttgaacag gcgggtacgg ttggcatgtg ttgcaacaac
     4261 tgttccgttg ccgggaagag ccaatccaat cgcttcgttc agacagttca tagagttagc
     4321 cgtgaacatg ccagaacagc aaccgcaggt cgggcaagcg gaacgttcca ccttttctac
     4381 ttgttcatcg ctgatagaat cgtcagccgc ttcaatcatg gcgtcgatca aatcgagtgc
     4441 acgtccgtcc agattaccgg cttccatcgg accgccggat acaaagattg tcggaatatt
     4501 cagacgcatg ctggccatca gcatacccgg agtaatcttg tcgcagttac tgatacaaac
     4561 cattgcatca gccttatgcg cattcaccat atattccaca ctgtcagcaa tgatgtcgcg
     4621 ggaaggcaga gaataaagca ttccgtcgtg tcccatagca ataccgtcat caatagcgat
     4681 cgtattaaat tctgcggcaa agcaaccgag cttttcgatt tccgctttta cctgctgtcc
     4741 gatctcgtgt agatgcacat ggcccggtac aaactgggta aatgaattca caatggcaat
     4801 gatcggttta ccgaattgtt cttctttcat gccgttggca cgccataatg cacgggcacc
     4861 ggccatacgt ctgccttctg tgctatagga gcttcttaac ggattcttca tcatatctgt
     4921 ttttatcttt tagtcaataa aaaagccctt ctctatatgg agaaaggctt aagaaatatc
     4981 ttttacgact tcacaacttc ttacacacct ttctccttac ctactaatga ctagaagg
//
