LOCUS       c00046_gnlPro..        15906 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBHCLEGA_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:58:31
            Original ID  :: gnl|Prokka|LBHCLEGA_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15906
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15906
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1916:5906]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1917..5906
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15906
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15906
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(186..1295)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MITWHEELTFDFSDPVSNEVFTENCIFFDIETTGFSPARTDLYLI
                     GCATRRDSLLCIDQFFSENAADQKNVLSAFLELLSGYDTILTFNGIGFDIPYLKAKCKA
                     LHLSDPFDAHSYIDLYKEVSRFKFLFALTSYKQKSIELFLGIDRIDAYSGGELIEVYKE
                     YVRHPAKDSLALLKQHNYEDVLYMPKLLPVLSYPKLWEQAFSLQSLQASEYRSMDGASG
                     NKELFFTLALQYPVPKPVSFSYDDCYLSMSGSTARLRVRLFEGELRFFYDGSPKDYYYL
                     PAEDIAVHKSIASAVDKEHRVQANASNCYGKKYAIFLPQYDAMFSPVFREQPRGRKCYF
                     ELSADFAADPAMQMDYVLHLLETMRSHRK"
     CDS             1917..2960
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="Fer4_9 (E-value: 5.7e-11, bitscore: 33.3,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5e-09, bitscore: 26.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.2e-09, bitscore: 28.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.3e-15, bitscore: 47.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.1e-54, bitscore:
                     175.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 16.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNSIVIENDGAFEEVEYTPCEDVTALSKEEIVNKVKEAGVVGMG
                     GAGFPTHVKLSPKEPEKIEYVIANCAECEPYLTADYRRMLENPEELIGGMKIILQLFDH
                     AKGVLGIEDNKPDCIEKLTELVKDEPRIEVCPLQTKYPQGGERQLIYAVTGRAINSKML
                     PADAGCIVDNVETIIAVYRAVKLGRPVTNRISTITGDAIANPGNFLYSIGTSYAELVEA
                     AGGFKTQPEKIISGGPMMGFAMFSLDIPTTKTSSSLLCLSKDEVSKVEPSACINCGRCV
                     EACPEQLIPSRLAKFSNNGLAEAFESWHGLECVECGSCSFVCPARRQLAQSIKTMKKQV
                     LAAKRKK"
     CDS             2993..3958
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.3e-119,
                     bitscore: 387.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSDLYHVSSSPHVRAKDTTSRIMLYVIIALLPTSLFGIYNFGYKA
                     LVLILVTIASCVASEWVFNKIVHKKQTIDDLSAVVTGLLLALNLPATLPWWEAVIGGVF
                     AIVVVKCLFGGLGQNFMNPALGARCFLLIAFAADMTKFGITKNGIEVYSSVTPLAAMRN
                     GEAVNTMDMLIGRTAGTIGETSAIAILIGAIFLILMGVINLRIPASYIITFAVFMLLFG
                     GHGFDGSYLTAQLCGGGLMLGAFFMATDYVTSPITPMGQIIFGICCGILTGLFRCFGAN
                     AEGVSFAIILSNILVPLIEKHTVPMAFGQVKEAKKQEGGK"
     CDS             3961..4569
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="FMN_bind (E-value: 2e-20, bitscore: 64.0,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIVHDALVLFAFTVVLGLILGVVYGITKGPIDQVNYEKTQSA
                     YKQVFEDADSFEEYADFDTAAAEDLMAQNGYSDDIEAVNTALDASGNPLGYVLTVTAKD
                     GSQGSITFSVGIQNDGTVNGYSITSISETPGLGMKAQEEPFYSQFEGKNVDSFTVVKST
                     PSADNEIEAISGSTITSKAMANGVNACLTYFHSVLEGGN"
     CDS             4573..5295
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-69, bitscore:
                     224.7, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKNVERLYNGLIKENPTFVLMLGMCPTLAVTSSAINGLGMGLST
                     TVVLVLSNMLISAFRKVIPDGVRMPAYIVIVASLVTVVQFIMQAYTPSLSESLGVYIPL
                     IVVNCIILGRAESYASKNPVVPSLFDGLGMGLGFTMGLTLIGLFRELLGAGQIFGFQIL
                     SLSWFTPITIFVMAPGAFLVLACLVAVMKIVREKMAAKGKPLAEPSGCITGDCAGCGMS
                     AACTGKKPAAEAPAEKAE"
     CDS             5310..5906
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.4e-65, bitscore:
                     210.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLLLIAIGSAIVNNVVLSQFLGICPFLGVSKKTETAAGMGGAV
                     VFVITISSFVTALIYKYILANSYLMSKGIDLTYLQTIVFILVIAALVQFVEMFLKKSMP
                     ALYQSLGVYLPLITTNCAVLGVALTNVTKEYGILESVVNGFATAFGFLIAIVLMAGVRE
                     KIEYNDIPKPFQGTAIVLISACLMSIAFMGFSGMI"
     CDS             complement(6046..6621)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MNCILRAVLLTQMTSDTSYGTCLHDILALILGAALYNVLCLVRNK
                     LDQMLRTCSNTFSTCLTYFLVNLRNAVHDMNRIKRTSLYTAAVSKASVITGLRSAVRHE
                     CHGCTVLVAGILVIASCLLTGSRTLYKCYLALAFLGCHTHDLTDLGCNRRAADRTLIDR
                     SLALCDCCCQTGTTGITTATTVISRKHT"
     CDS             complement(6832..7869)
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MRKKKVLSCLLVPLLSANLLLSGCSRTADEPVTKSGFYFNTVISV
                     SIYEKGSEELLDDCFALAQKYEGYFSNTIPDSDISKINDAGGAPVTVHDETIELLKTGI
                     AYGDLSGGKFDITIGRLSDLWDISTKALLDQTDASMIPSDADIQTALATVDYREIQIDG
                     NTVTLQNPDTRIDLGGIAKGYIADQMKAYLNQKGITSGYINLGGNVLALGAKTDGSAYT
                     IGIQRPFGEENEAIASVSITDQTVVSSGVYERYFEVDGTRYHHILDTATGYPYDNGLLE
                     VTIITGASVDGDGLSTTCFSLGLEDGMALVESLDATEAIFITDDYEVHTSSGMGTVIPY
                     EILED"
     CDS             8051..8902
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="AA_kinase (E-value: 8.7e-44, bitscore:
                     140.6, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKHFHFNEKKRVVVKIGSSSLNYGETGNLNFTKLEHLVRELCN
                     LRNRGMDVCLVSSGAIAVGRQTLGMDERPKDISTKQACAAVGQARLMMIYQRLFAEYNQ
                     VAGQVLMTKNTMVNPVSRENAKNTFDELFRLGAIPIVNENDTVSTYEMQFGDNDTLSAI
                     VASLIGADLLILLSDIDGLFTDDPHKNPDAKLIEVVEEMDASIYGMAKSSTGSDVGTGG
                     MATKLTAAKIATLSGTDMIIANGRDVCILHHIFDDSFKGTIFQAKKKESFRIEDFILET
                     IG"
     CDS             8924..9148
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MNQEQIDRINALYRKSKAEGLTEEEKKEQALLRKQYVADVKKNLA
                     AQLNNIDMVNPDGSVENLGDKYGKKTGLS"
     CDS             9123..9767
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MEKRQDFPDAALTQEKARQQIRARHKAWRMELPQEEVQEKSRKIC
                     ERLAASDWYHNSAVIYGYYPLGAEADCLPFLAQALSDGKTVALPVTSKERLQRDCGQVK
                     RMQDTHRMEFYRIRELSRVREGAFHVMEPDESCKRIGEEDAVVLVPGLVFDRKGNRYGY
                     GGGYYDRYFARFPKLSRMAVAFEGQIEEQLAVLPTDVRMHRIYTEEREYRI"
     CDS             9787..11070
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_12"
                     /sec_met_domain="Aldedh (E-value: 5.3e-24, bitscore: 75.2,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTELCKSAKEVSRQIGNLDTNTKNEVLRAAAEALVAHTDEIIR
                     ENEKDLARGRENHMPEGLLDRLMLTPSRMEQMAEGLRQVADLADPIGEVLSMKKRPNGL
                     MIGKKRVPLGVVGMIYEARPNVTVDAFALCFKTGNAVILKGGSDAILSNIVIVSVLQEV
                     LEAHGIPRAAVSLIEDTSRETAAAFMKMNEYVDVLIPRGGAGLIRAVVNQATIPVIETG
                     TGNCHIYVDESADFDMAIRIILNAKTQRIGVCNACESLVIHEKIVDAFMPKLAAALQQK
                     DVVIHADEKSLAAAERREAANGGDLKKELLSAATEEDWGREYLDYMISVKTVSSLDEAI
                     AHINRYNTGHSEAIITENYTNAQRFLDEIDAACVYVNASTRFSDGFEFGFGAEIGISTQ
                     KLHARGPMGLDALTSTKYIIYGNGQTRP"
     CDS             11086..12549
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_13"
                     /sec_met_domain="Radical_SAM (E-value: 2e-36, bitscore:
                     116.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKIDIEIIDKKQIPQSEPERQYYFMDIAKNYVEQLSAKKGSPL
                     TFHVTTFGCQMNARDSEKLVGILERIGYVETDTEDADFVIYNTCTVRENANNKVYGRLG
                     VLQNYKKKNPHMLIGLCGCMMQETVVVEKLKESYRFVDLIFGTHNIYKFAELIVTAMES
                     DSMTIDIWKDTDQIVEDLPVERKYSFKSGVNIMFGCNNFCSYCIVPYVRGRERSREPKE
                     IIREIEQLVADGVVEVMLLGQNVNSYGKNLKEPVTFAQLLEEVEKIEGLERIRFMTSHP
                     KDLSDELIEVMGRSKKICKHLHLPLQSGSSRILKIMNRRYDKEHYLELVDKIRAAVPDI
                     ALTTDIIVGFPGETEEDFEETMDVVRKVRYDSAFTFIYSKRTGTPAASMEEQVPEDVIK
                     ARFDRLLKEVQKISAEKAGALTGQTLPVLIEEQNEQDASLVTGRLSNNSVVHLPGTADM
                     IGKILDVKLTECRGFYYLGERADGKGQTV"
     CDS             12573..12932
                     /locus_tag="ctg46_14"
                     /transl_table=11
                     /translation="VIFLAILLAVVTVFLVVYERMGTRADAGACVRVTVDGSVYGIYVL
                     GEEQEIPIVQDGVTTNVLTIRDGRADMTEADCPDKLCVHQKAISKNHEMIVCLPNKVVV
                     EVTGSEENGFDSIAR"
     CDS             12922..13416
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="LRDKVAYLGVFLALALICSYVESLIPFYFGIPGVKLGLTNIVVVL
                     MLYCVGTKEAFAISMLRIVLAGFLFGNLFSILYSLAGGMFSFLVMYLLKRTGKLGVLPV
                     SVAGGMSHNIGQIAVAAFVVENINIFYYLPVLFVAGIVTGLLIGVAAQEIILRIGGRLK
                     R"
     CDS             13430..14041
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="VYAYIKGVLADVEEESVVVEAGGIGYRIYTTGQTFDYLPAVGEEV
                     KLYTYLNVREDAMILYGFLTKDDLRVFKLLIGVNGIGPKGALAVLSVMTTDDLRFAVLG
                     DDAKAIAKAPGIGAKTAQRVILELKDKLSLEEAFELKSEHVSRQNENGSSGVKNEAVQA
                     LVALGYASSEALKALNGIEITDDMDVETLLKAALKNMAFL"
     CDS             14081..15079
                     /locus_tag="ctg46_17"
                     /transl_table=11
                     /translation="MEKRVISTQVQEEDLKIEKSLRPQTLDDYIGQQKAKENLKIYIEA
                     AKARGESLDHVLFYGPPGLGKTTLAGIIANEMGTHMKVTSGPAIGKPGEMAAILSNLQE
                     GDVLFVDEIHRLNRQVEEVLYPAMEDYAIDIMLGKGATARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVVHHLEFYTVEELKTIILHSALTLGVEIDEEGAYEMARRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRISKEVASFALDLLEVDKMGLDQNDRNILMTMIGKFAGGPVGL
                     DTLAAAIGEDAGTIEDVYEPYLVKNGLINRTPKGRVVTELAYQHLGIEHSV"
     CDS             15158..15598
                     /locus_tag="ctg46_18"
                     /transl_table=11
                     /translation="MAEKTSAEVIIGGKVYTLSGYEGEEYLQKVATYINNKLGEFQGME
                     ELRHLSGDMKATLLQLNIADDYFKAKTQVEKLEREIEQKEKEIYDLKHDLISNQIKAES
                     DEKARKELEEQNKELLINKAKLEASLEDALLGKVTEKDKTEE"
ORIGIN
        1 atgaattacc gggagatcgg atttgagaga gacaagtcct ttttctttga gaaggcgtaa
       61 ggttatatca gaggacgcat ttttctataa agcaaaaaag cggcaggaaa gaagctgtgc
      121 agtatatgcc agattctttc ctgccgtttt tggtggtaat tatatcaggg ctttctgcca
      181 tgtgtttatt tgcggtggga acgcatggtt tctaacagat gcagaacata gtccatctgc
      241 atagcgggat cggcggcaaa gtccgcggat aattcaaaat agcatttcct gccgcgcggc
      301 tgttcacgga acaccgggga aaacatggcg tcatactgcg gaagaaagat ggcatatttt
      361 ttgccgtagc agttggaagc gttcgcctgc acgcggtgtt ctttgtcgac ggcggatgca
      421 atactcttgt gaactgcgat atcctccgca gggagatagt agtaatcttt gggactgccg
      481 tcataaaaga agcgcagttc tccctcgaag agacgtacac gcagccgggc ggtacttccg
      541 ctcatggaga gataacagtc atcgtaggag aaggagaccg gtttgggaac ggggtactgc
      601 agcgccagtg taaaaaacag ctccttgttg ccggaggcac cgtccatcga ccggtactcg
      661 gacgcctgga gtgactgcag agaaaatgcc tgttcccaga gttttgggta ggagaggacg
      721 ggcagaagct tcggcatata gagaacgtcc tcatagttgt gctgtttcag cagtgcaagg
      781 gaatcctttg cgggatgccg cacgtactct ttgtagactt cgatcagctc gccgccggag
      841 taggcgtcga tgcggtcaat cccgagaaac agttcgatgg atttctgctt gtagctggtc
      901 agggcaaaca gaaatttgaa acgtgagact tccttataaa gatcgatata actgtgcgca
      961 tcaaacggat cggaaaggtg cagcgccttg catttcgcct tcaggtatgg aatgtcgaag
     1021 ccgataccgt tgaacgtcag aatggtatca tagccggaca agagctccag aaaggcggaa
     1081 aggacatttt tctgatcggc ggcgttctcg gaaaagaact ggtcgatgca caaaagactg
     1141 tcgcgccttg tggcgcagcc gatcaggtag agatccgtgc gcgccggcga gaagccggtt
     1201 gtctcaatat caaaaaaaat gcagttttct gtaaatacct cgttggaaac ggggtctgaa
     1261 aaatcaaaag tcagttcttc atgccaggtt atcatctgaa aatcctctgt atgtaatatt
     1321 agggtaagag ttccaatttt gccgctgtgc aggtctggaa aggcatagat ttcccggact
     1381 cgcgggcgcg ttcacatgga gcagaaccat ccgctgcatg caagcatgag cgtatgtttt
     1441 tgctccatgc tcacttttgc cttcacgtac attataacat aaatgtggaa aaaatattgt
     1501 gaattctttg tcaataggtt cgtgaaaaaa tacaataaat tgctacaatt tccgagtgat
     1561 tgtgctataa tctacacgag ggtattctat gacttttggc atagaatata atatagataa
     1621 gagaaagtgg ggcacgagaa atgggttcta agacatttaa aggcggcgtc catccttatg
     1681 aaggaaagga actggcaaag gatcagccga tcgtagaagt tctacctaag ggtgatctgg
     1741 tatacccgtt gtcacagcat atcggtgcac cggcgactcc ggtggtagcg gttggtgaca
     1801 aggtgctgaa aggacagaag atcgcagagg caggtggctt tgtgtcatcc ccgatctatg
     1861 cgtcggcatc cggtacagta aaggcaatcg aaccgcaccg tgtggcagtc ggtgacatgg
     1921 tgaattccat cgtcattgag aacgacgggg cgtttgaaga ggtggagtac acgccgtgtg
     1981 aagacgtgac ggctctctcc aaggaggaga ttgtcaataa ggtaaaagag gcaggcgttg
     2041 tcggcatggg cggtgcaggt ttcccgacac atgtgaagct gtctccgaaa gagccggaaa
     2101 agattgaata tgtaattgca aactgcgcag agtgtgagcc gtatctgacg gcggactacc
     2161 gcagaatgct cgaaaatcca gaagagctga tcggtggaat gaagatcatt ctccagctgt
     2221 tcgatcatgc gaagggtgtt ctcggcatcg aggacaacaa gccggattgt attgaaaagc
     2281 tgacagagct tgtcaaggat gaaccgagaa ttgaggtctg tcctttacag accaagtacc
     2341 cgcagggtgg tgagcgtcag ctcatttatg cagtgacagg ccgcgccatc aattccaaga
     2401 tgcttccggc agatgcagga tgtatcgtgg ataatgtgga gaccatcatt gctgtttacc
     2461 gtgcggtaaa gcttggcaga ccggtaacca atcgtatttc tacgattaca ggcgatgcca
     2521 ttgccaaccc gggcaacttc ttatacagca tcggtaccag ctatgcagaa ctggtggagg
     2581 ctgccggcgg atttaagaca cagccggaga agattatttc cggtggtccg atgatgggat
     2641 ttgcaatgtt tagcctggat attcccacga caaagacatc ttcctcactg ctttgcttaa
     2701 gcaaggacga agtgtccaag gtggagccgt ccgcatgtat caactgcggc cgctgtgtgg
     2761 aagcatgccc ggagcagctg attccgtcaa gacttgccaa gttttccaat aacggtctgg
     2821 ctgaggcgtt tgaatcctgg cacggactcg agtgcgtgga gtgcggaagc tgcagttttg
     2881 tatgccctgc acgcagacag ctcgcacagt ccattaagac gatgaaaaag caggtacttg
     2941 ctgcaaaacg caaaaaataa ttcaaaaaac aagaagagag aggtggatta tcgtgagtga
     3001 tttatatcat gtttcatcat caccacacgt tcgtgccaaa gataccacaa gccgtattat
     3061 gctgtatgtg attattgcat tgcttccgac aagcctgttc ggaatttaca atttcggata
     3121 taaggcattg gttctgattc tggtaacgat tgcaagctgt gtggcatcag agtgggtatt
     3181 taataagatt gtacataaaa agcagacgat cgatgacctg agcgccgttg taacgggact
     3241 gcttctggca ttgaaccttc cggcaaccct tccgtggtgg gaggcggtaa tcggcggtgt
     3301 gtttgcaatc gtggttgtaa aatgtctgtt tggcggactg ggacagaatt tcatgaaccc
     3361 ggcgctgggc gcaagatgct tccttttgat tgcatttgct gctgatatga caaagtttgg
     3421 catcacaaag aacggtattg aagtgtattc cagcgtaaca ccgcttgctg ccatgcgtaa
     3481 cggtgaggcg gtcaatacga tggatatgct gatcggacgc accgcaggta ccattggtga
     3541 gacatctgcg atcgctattc tgatcggagc tattttcctg atcctgatgg gtgtgatcaa
     3601 ccttcgcatc ccggcatctt acattattac atttgctgta ttcatgcttt tattcggcgg
     3661 tcatggattt gacggcagct atcttaccgc acagctttgc ggcggcggtc tgatgctcgg
     3721 cgcattcttc atggcaacgg attatgtgac atccccgatt acaccgatgg ggcagatcat
     3781 ctttggtatc tgctgcggta tcctgaccgg attgttccgc tgcttcggcg cgaatgcaga
     3841 gggtgtttcc ttcgccatca tcttaagcaa tatccttgtg ccgcttattg agaagcacac
     3901 ggtgccgatg gcattcggtc aggtgaagga agcgaagaag caggaaggag gcaaatagaa
     3961 atgaacaaga agattgtaca tgacgcattg gttttatttg cttttactgt tgtattaggt
     4021 ctgatcctcg gcgtggtcta cggcattacc aaaggcccga tcgaccaggt aaattatgag
     4081 aagacacagt ccgcttacaa gcaggtattt gaggatgcgg attcctttga ggagtacgct
     4141 gatttcgaca ccgctgcagc ggaagatctt atggcgcaga atggatattc tgacgatatc
     4201 gaggctgtca acacagcact tgacgcttcc ggcaatccgc tcggctatgt gcttaccgta
     4261 acggcgaagg acggaagcca gggcagcatt acattctctg tcggcatcca gaatgacggt
     4321 acggtcaatg gttattccat cacaagtatt tccgagacac cgggacttgg tatgaaagca
     4381 caggaagagc cgttctacag ccagtttgag ggcaagaacg tagactcctt tacggttgtg
     4441 aagtcgacac cgtctgcgga caatgagatc gaggcaattt ccggttccac cattacttcc
     4501 aaggcgatgg cgaacggtgt gaatgcctgc cttacatact tccacagcgt attagaagga
     4561 ggtaactaat caatgaacaa gaatgtagaa cgtttatata atggactcat taaggaaaat
     4621 cctactttcg ttctgatgct tggtatgtgt ccgacacttg ctgtcacatc ctccgcaatc
     4681 aacggacttg gcatgggact ttccacaaca gtggtactgg tactttccaa tatgctgatt
     4741 tccgcattcc gtaaggtgat tccggacggc gtgcgtatgc cggcatacat tgttatcgtt
     4801 gcatcgctgg taacagtggt gcagtttatc atgcaggcgt atactccgag cctctccgag
     4861 tcgctgggtg tgtacatccc gttaatcgtt gtaaactgta ttatcctcgg ccgtgctgag
     4921 agctatgctt ccaagaatcc ggtagttccg tctcttttcg atggacttgg tatgggactt
     4981 ggatttacga tgggtcttac cctgatcgga ctgttccgtg agcttctggg cgcaggtcag
     5041 atctttggtt tccagattct gtccttaagc tggttcacac cgatcaccat ctttgttatg
     5101 gcaccgggag cattcctcgt actggcatgt ctggtagctg tgatgaagat cgtacgtgag
     5161 aagatggcag ccaagggcaa gccgcttgcc gagccgtccg gatgtatcac tggagactgt
     5221 gcaggatgcg gtatgtctgc tgcatgcacc ggtaagaaac cggcagcgga agctccggca
     5281 gaaaaagcag aataggagga tagatacgga tgaaaacatt acttttaatt gcaatcggct
     5341 ctgccattgt caataacgtt gtattaagtc agttccttgg tatctgtccg tttttaggcg
     5401 tttccaagaa aacagagacc gctgccggaa tgggtggcgc agttgtattc gttatcacga
     5461 tctcttcgtt cgtgacagcg ctgatctaca aatatatcct tgccaacagc tatctgatga
     5521 gcaagggcat tgatcttact tacctgcaga cgatcgtgtt tattcttgta atcgctgcac
     5581 tggtacagtt cgttgagatg ttcttgaaga agtccatgcc ggcattatac cagagccttg
     5641 gtgtatacct tccgctgatt acgacaaact gtgccgttct cggtgttgca ctgacgaatg
     5701 ttaccaagga atacggtatt ttggagagtg tggtaaacgg ttttgcaacc gcatttggtt
     5761 tcctgattgc gatcgtttta atggcaggtg tgcgtgagaa gatcgagtac aatgatatcc
     5821 cgaagccgtt tcagggtact gcaatcgtat tgatttccgc atgtctgatg tcaatcgcat
     5881 tcatgggatt ctcaggaatg atttaggagg aaaaagaaga tgaacgttac agcaatttta
     5941 tttgcagcct taattgtggg cggcgtaggt atcttgattg gatttttcct tggtatttcc
     6001 ggagaaaagt tcaaggtaga ggtagatgaa aaagaggaag caatcttagg tgtgcttccg
     6061 ggaaataact gtggtggctg tggttatgcc ggttgttccg gtctggcagc agcaatcgca
     6121 aagggcgagg ctccggtcaa tcagtgtccg gtcggcggcg cgccggttgc agccaagatc
     6181 ggtgagatca tgggtgtggc agccgaggaa ggcgagcgca aggtagcatt tgtaaagtgt
     6241 gcgggaacct gtgagaaggc aggacgcgat tacgagtata ccggcaacga ggactgtgca
     6301 gccatggcat tcgtgccgaa cggcggaccg aagtcctgta attacggatg ccttggatac
     6361 ggcagctgtg taaaggcttg tccgtttgat gcgattcata tcgtggacgg cattgcgcag
     6421 gttgacaagg aagtatgtaa ggcatgtgga aaatgtgttg ctgcatgtcc gaagcatctg
     6481 atcgagcttg ttccttacaa ggcaaagcac attgtacagt gcagctccaa ggataagggc
     6541 aaggatgtca tgaaggcatg ttccgtagga tgtatcggat gtcatctgtg tgagaagaac
     6601 tgcccgaagg atgcagttca tgtcattgac aacgtggcat acattgatca ggagaagtgt
     6661 gtcggatgcg gtatctgtgc acagaagtgt ccaaagaaaa ttattctgta agaatgattt
     6721 tctccgaaaa tcatcctgta agaatcgttt cttggaatga aagtgtgaaa taaaaacagg
     6781 cgtgaagaat tcgcggtaat aagtacgaat tcttcacgcc tgttttgttg tttaatcttc
     6841 cagaatctca tatggaatga cggttcccat gccggagctg gtgtgtactt catagtcgtc
     6901 tgtgatgaaa atagcttccg tagcatcaag gctttcaacg agcgccatac cgtcttccag
     6961 cccgagggag aaacaggtgg tggagagacc gtcgccgtcc accgatgcac cggtgatgat
     7021 cgtgacctca aggagcccgt tatcgtaagg gtaaccggtc gcggtgtcca ggatatggtg
     7081 ataacgcgtc ccatctactt caaaatagcg ttcgtagacg ccggaggata cgacggtctg
     7141 atcggtgatg gagacggagg caatcgcttc gttttcctca ccgaacggac gctgtatgcc
     7201 gatggtgtat gccgaaccgt ccgtcttcgc gccgagcgca agcacatttc cgcccagatt
     7261 gatgtaaccg gaagtaattc ccttctggtt caggtaggct ttcatctgat ccgcgatata
     7321 gcctttggcg atgccgccca gatcaatcct ggtatcggga ttttgcagag tcactgtgtt
     7381 gccgtcaatc tgaatctccc ggtaatccac tgtggcaaga gccgtctgaa tgtccgcgtc
     7441 ggaggggatc atggaggcat cggtctgatc aagcagcgct ttggttgaga tgtcccacag
     7501 atcggaaagc cggccgatgg tgatgtcgaa tttgccgccg cttaagtcgc catatgcgat
     7561 gccggtttta agaagttcga tcgtttcgtc gtgtactgtc acgggagcgc cgcccgcatc
     7621 gttgattttg gaaatatcgc tgtccggaat cgtattggaa aaatatccct cgtacttttg
     7681 tgcaagggca aaacagtcat cgagcagttc ctcgctccct ttttcataga tcgagactga
     7741 gatgacggtg ttaaaataaa atcctgactt ggtaaccggt tcgtccgccg tgcggctgca
     7801 gccggagagc agcagatttg cagagagcag gggaaccaga agacaggaga gtaccttctt
     7861 ttttctcatc ataaaaatct ccatttctga tgtttcccat ccaatgtacc ataaactttc
     7921 tgttcataca atgtgaaaac atcaatttgc cattttgatg aagatatgat agagtaatac
     7981 agtatgagac tctatgccca tttgggatga atgattggaa aatgttacat ataaagggga
     8041 cgttagacag atggaacaaa agcattttca ttttaatgag aaaaagagag ttgtagtcaa
     8101 gatcggatct tcctcactga attacgggga gacgggcaat ctgaatttta ccaagctgga
     8161 gcatctggta agagaactct gcaatctgcg gaaccgcggg atggatgtgt gtctggtaag
     8221 ctccggtgcg attgccgtgg gcagacagac gctcggcatg gatgagcggc cgaaggacat
     8281 ttcgacaaag caggcatgcg cggcggtcgg ccaggcgcgg ctgatgatga tctatcagcg
     8341 gctttttgcg gaatacaatc aggtggcagg gcaggtgctg atgacgaaga acacgatggt
     8401 gaaccctgtc tcgagagaga atgcgaagaa tacgttcgac gaattgttcc gtcttggcgc
     8461 aatcccgatt gtgaatgaaa atgatacggt ttctacttat gagatgcagt ttggcgacaa
     8521 cgacacgctc tcggcaatcg tggcttctct gatcggggcg gatcttttga tcctgctctc
     8581 ggatatcgat gggcttttta ccgacgatcc gcacaagaat ccggatgcaa agctcattga
     8641 agtggtggag gagatggatg cgtcgatcta cggcatggcg aaaagttcga ccggcagtga
     8701 tgttggaacc ggcggcatgg caaccaaact gacagctgca aagattgcaa cgctctcggg
     8761 aacagacatg attattgcga acggcaggga tgtctgcatt ctgcatcata tatttgatga
     8821 ttcctttaag ggaaccattt ttcaggcaaa gaagaaagaa tctttccgga ttgaagattt
     8881 tattttggag acgatcggtt aagaatacag gaaaaggagc actatgaacc aggaacagat
     8941 tgacagaatc aatgcgttat accgcaagtc gaaggcggaa gggctgacgg aggaagaaaa
     9001 aaaggagcag gcgctgctgc gcaagcagta tgttgcggat gtgaagaaaa atctggcggc
     9061 gcagcttaac aatatcgata tggtgaatcc ggacggttct gtggagaacc ttggagataa
     9121 gtatggaaaa aagacaggac tttcctgacg cagcgctgac acaggagaag gcgcggcagc
     9181 agataagggc gcggcacaaa gcatggcgga tggaactgcc gcaggaggaa gtgcaggaaa
     9241 aaagcagaaa gatctgtgag aggttggcgg cgtctgactg gtatcataac agcgctgtca
     9301 tctacggcta ttatccgctc ggcgcggagg ctgactgtct gccgtttctg gcacaggcac
     9361 tttcggacgg caagacggtg gcgcttccgg ttacatcaaa agagcggctg cagcgggact
     9421 gcggccaggt gaagagaatg caggacacac accggatgga gttttaccgg atcagagagc
     9481 tttccagagt gcgggagggc gcctttcatg tgatggagcc ggatgagagc tgcaaacgga
     9541 tcggggaaga ggatgcggtg gtgctggtgc ccggactggt ctttgaccgt aaggggaacc
     9601 ggtacgggta tggcggcggt tattatgacc gctattttgc aaggtttccg aagctgtccc
     9661 gcatggcggt agcgtttgaa gggcagatcg aggaacagct tgcggtgctt cccaccgacg
     9721 tgcggatgca tcggatttat acggaggagc gggaatatcg gatctgacag aaaggatgga
     9781 aaggatatgg aactgacaga actttgtaag agcgcaaaag aagtgagcag acagatcggc
     9841 aatctggaca cgaatacgaa gaacgaggtg ctgcgtgcag cggcagaggc acttgtggca
     9901 cataccgatg agattatccg cgagaatgag aaggatctcg cccgtggcag agaaaatcat
     9961 atgcccgagg gactgctgga ccgtctgatg ctcaccccat cccggatgga gcagatggcg
    10021 gaggggctgc ggcaggttgc agaccttgcc gatccgatcg gcgaagtcct ttccatgaag
    10081 aagcgcccga acggtcttat gatcggtaaa aagcgtgtcc cgctcggtgt ggtcggcatg
    10141 atctatgagg cgagaccgaa tgtgacggtg gatgcgtttg cgctgtgttt taagacgggc
    10201 aacgcagtga tcttaaaagg cggcagtgac gccattttgt ccaatatcgt cattgtttcg
    10261 gttctgcagg aagttttgga ggcacatggc attccgcgtg cggcagtatc gctgattgaa
    10321 gatacaagcc gggagacggc ggctgcgttc atgaagatga acgaatatgt ggatgtgctg
    10381 attccgcgcg gaggagcagg gctgatccgc gccgtcgtca atcaggcgac gattcctgtg
    10441 attgagacgg gaaccggcaa ctgtcatatc tatgtggatg agagtgcgga tttcgatatg
    10501 gcaatccgta ttattttaaa cgcaaagacc cagcggatcg gtgtgtgcaa tgcctgtgaa
    10561 tcactcgtga tccatgagaa aatcgtggat gcatttatgc caaagcttgc ggcggcactg
    10621 cagcagaagg atgttgttat tcatgcggat gagaaaagtc ttgcagcggc agagcgccgg
    10681 gaggcggcaa atggcggaga cctgaaaaag gaactgttgt cggcggcgac ggaggaagac
    10741 tggggcaggg agtatctcga ttatatgatc tccgtgaaga cggtgtcgtc cctcgacgag
    10801 gcgatcgcac acatcaaccg ctacaatacc gggcattcgg aggcaatcat cacagaaaac
    10861 tacacgaacg cgcagcggtt cctggatgag atcgatgctg cctgcgtcta tgtcaacgca
    10921 tcgacgcgtt tttcagacgg atttgaattt ggatttggcg cggagatcgg catcagtacc
    10981 cagaagcttc atgcaagagg accgatggga ctggatgcgc tgaccagcac aaaatatatt
    11041 atatatggaa acgggcagac acgtccgtag atggtaagga tgaagatgaa aaagaaaata
    11101 gacattgaaa taatcgataa aaagcagatc ccgcagagcg agccggagcg tcagtattac
    11161 tttatggaca ttgctaaaaa ttatgtggaa cagctctctg caaaaaaagg cagtccgctg
    11221 acctttcatg tcacgacgtt cggctgccag atgaacgcgc gcgattctga gaagcttgtc
    11281 ggtatcttag agcgcatcgg ttatgtggag acggatacgg aggacgcgga ttttgttatt
    11341 tacaatacct gcacggtgcg tgaaaatgca aataacaaag tctacggaag actcggggta
    11401 ctccagaatt ataaaaagaa aaatccacat atgctgatcg gactctgcgg ctgtatgatg
    11461 caggagacgg tagttgttga aaaattaaaa gaaagctacc gctttgtgga tctgatcttc
    11521 ggaacacata atatctacaa atttgcagag ctgattgtga cggcgatgga atcggattcc
    11581 atgacgattg atatctggaa ggacacggac cagatcgtgg aggacctccc ggtagagcgg
    11641 aagtattcgt ttaaatccgg cgtcaatatc atgttcggat gcaataattt ctgcagctac
    11701 tgtatcgtac cgtatgtgcg cggaagggag cgcagcaggg agccgaaaga gatcatccgt
    11761 gagatcgaac agctcgtggc ggacggcgtt gtcgaggtca tgctgctcgg acagaatgtc
    11821 aattcctacg gcaagaatct gaaggagccg gtgacgtttg cgcagctttt agaggaagtg
    11881 gagaagattg aggggttaga gcgtatccgt tttatgacct cccacccgaa ggatctctcg
    11941 gacgagctga tcgaggtgat gggacgatcc aaaaagatct gcaaacatct gcacctgcca
    12001 ttacagtccg ggagcagccg gatcttaaag atcatgaacc gcagatatga taaggaacat
    12061 tatctggaac tggtggacaa gatccgcgcg gcagtgccgg acattgcgct gacgacggat
    12121 attatcgtgg gtttcccggg ggagacggag gaggacttcg aggagacgat ggacgtggtg
    12181 agaaaagtgc gttatgacag cgcatttacg tttatctatt ccaagcgtac cggaacaccg
    12241 gcggcatcca tggaagagca ggtgccggag gatgtgatca aggcgcgttt tgaccgcctg
    12301 cttaaggaag tgcagaagat ctccgcagaa aaagcggggg cgctgaccgg acagacgctg
    12361 ccggtgctga ttgaggagca aaacgagcag gatgcttcgc ttgtgacggg aagactcagc
    12421 aataactcgg tggtacatct gccggggaca gcggacatga tcggaaagat tctggatgta
    12481 aagctgaccg agtgccgggg cttttattat cttggcgagc gggcagacgg aaaaggtcag
    12541 acggtatgaa aaagcgaatc agcagaaacg atgtgatttt tcttgcaata ctgcttgccg
    12601 tggttacggt atttcttgtg gtctatgagc ggatgggaac gcgcgcggat gcgggtgcct
    12661 gtgtgcgcgt caccgtggac ggcagtgtgt acgggatcta tgtgctcggg gaggagcagg
    12721 agataccgat tgtgcaggac ggcgtgacaa cgaatgtcct gacaatccgc gatggcaggg
    12781 cggatatgac ggaggcggac tgcccggaca agctgtgtgt tcatcagaag gcaatctcta
    12841 agaatcatga gatgattgtc tgtctgccga acaaagtggt tgtggaggtg acgggaagtg
    12901 aagaaaacgg attcgactcc attgcgagat aaggtggcgt atctcggggt ttttcttgcg
    12961 cttgccttaa tctgcagcta tgtggaatcc ctgatcccgt tttatttcgg aataccgggg
    13021 gtaaagctgg ggctcaccaa tattgtggtg gtactgatgc tgtactgtgt cggcactaag
    13081 gaggcgtttg ccatctcgat gctccggatt gtactggcgg gttttctgtt cggcaatctg
    13141 ttcagtatct tatacagcct tgccggcgga atgttcagct ttctggtgat gtatcttttg
    13201 aaacggaccg gaaagctcgg tgtgctgccg gtcagcgtcg cgggcggaat gtcacacaac
    13261 attggtcaga ttgccgtggc ggcgtttgtg gtggagaata tcaacatttt ttactatctg
    13321 ccggtgcttt tcgtggcagg catcgttacg ggactgctga tcggtgtggc agcccaggag
    13381 atcatactaa ggattggcgg acggctgaaa cgataaggag gaaatacgtg tgtacgcata
    13441 tataaaaggc gtccttgcgg atgtggaaga agagagcgtg gttgtggagg caggcggaat
    13501 cggataccgg atctatacga ccgggcagac gtttgactat cttccggctg tgggagagga
    13561 agtcaagctc tatacgtatc tgaatgtgcg cgaagatgcg atgattctgt acgggttttt
    13621 gacgaaggat gatctgcgtg tcttcaagct gttaatcggc gtcaacggta tcggcccgaa
    13681 gggggcgctg gcggtgctgt ctgtgatgac aaccgatgat ctgcgatttg cggtgcttgg
    13741 cgatgacgcg aaggcgatcg ccaaagcgcc cggaatcggt gcaaagacgg cacagcgtgt
    13801 gattttagaa ctgaaggaca agctgtcgct tgaggaggcg tttgaactca aatccgagca
    13861 tgtgagcaga cagaacgaga acggaagcag cggtgtgaag aatgaggcgg tgcaggcgct
    13921 tgtggcgctc ggctatgcct cttcggaagc gttaaaggcg ttaaacggca ttgagatcac
    13981 ggatgatatg gatgtggaaa cactgttaaa agccgcgctt aagaatatgg cattcctgta
    14041 gtaagggaag cggcaaggcg gaagaaagga aagctgggac atggagaagc gggtcatatc
    14101 cacgcaggtg caggaggaag atcttaagat cgagaaaagt ctccggccgc agacgctgga
    14161 cgattatatc ggacagcaga aggcaaagga aaatttaaaa atatatatcg aggcggcaaa
    14221 ggcgaggggg gaatccctcg accatgtgct gttctacgga ccgcccggac ttggaaagac
    14281 cacgctcgcc ggaatcattg ccaatgagat gggaacacat atgaaggtca cttcgggacc
    14341 tgccatcgga aaaccggggg aaatggcagc gatcctaagc aatctgcagg agggagatgt
    14401 cctctttgtc gacgagatcc accggctgaa ccgccaggtg gaggaggtgc tgtacccggc
    14461 aatggaggat tatgccattg atatcatgct tggcaaggga gccacagcgc gctccatccg
    14521 tctggatctg ccgaagttta ccctggtggg agcgaccacg cgcgcgggac ttttgtcggc
    14581 accgttaaga gaccgttttg gcgtggtgca tcatctggag ttctacacgg tggaggagtt
    14641 aaaaacgatc atcctgcatt cggcattgac acttggggtg gagatcgatg aggaaggtgc
    14701 ttacgagatg gcgagacgct cgcgcggaac cccgcgtctg gcgaaccggc tgttaaagcg
    14761 cgtgcgcgat ttcgcgcagg taaaatacga cggccggatt tcaaaggagg tagcgtcctt
    14821 tgcactggat ctgctggagg ttgacaagat ggggctcgat caaaatgaca ggaacatttt
    14881 gatgacgatg atcggaaaat ttgcgggcgg accggtcggg ctggacacgc tggcggcagc
    14941 gatcggtgag gatgccggaa ccatcgagga cgtatatgaa ccgtatctgg taaagaacgg
    15001 gctgatcaac cgcacgccga agggacgggt ggtgacagag ctggcatacc agcatctggg
    15061 aatcgaacat tccgtataga aatagttgct tttccttaaa tatgtcagta taatatacta
    15121 tatattgtag cggatacccg agtttggagg aaatggtatg gcagagaaga caagcgccga
    15181 agtgatcatc ggtggaaagg tatacacact gagcggttat gagggcgagg agtacctaca
    15241 gaaggttgcc acctatatca acaataagct gggcgagttt cagggcatgg aagagttaag
    15301 acatctatcc ggcgacatga aggcgacgct gttgcagtta aatatcgcgg atgattactt
    15361 taaggcgaag acacaggtgg agaagcttga gcgtgagatc gagcagaagg aaaaggaaat
    15421 ctacgatctc aaacatgatc ttatttccaa tcagatcaag gcagagagcg acgagaaagc
    15481 cagaaaagag ctcgaggagc agaacaagga gcttttaatc aacaaggcta agctggaggc
    15541 gagtctcgag gatgcgctgc tcggcaaagt aacggaaaaa gataaaacag aagaatagac
    15601 aatacgggga cgtaagagat ttgctttcgt cccttatttt catataacag gtaagaaaaa
    15661 tgatgcagaa aagagaattg gagctgctgg ctccggcggg atcatacgag acgtttgagg
    15721 cggtcatacg ggcgggggcg gacgcggtat atctgggcgg cagccatttt ggagcccgcg
    15781 catatgcgaa taattttaat gaggaagaat tgctgcgtgc catcgactat gcacatatcc
    15841 atggcagaca ggtgtatctg acggtgaaca ccctgttcaa ggaggaggaa ctggaacagg
    15901 gactct
//
