LOCUS       c00009_gnlPro..        16120 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POFDPHHH_9.
ACCESSION   c00009_gnlPro..
VERSION     c00009_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:01:36
            Original ID  :: gnl|Prokka|POFDPHHH_9
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 17356
            Orig. end    :: 33476
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16120
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[27356:32705]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15349
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..16120
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16120
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(359..961)
                     /locus_tag="ctg9_18"
                     /transl_table=11
                     /translation="MKLAKKFMTLALATALGVGCATVGVSAAGSRTSAITVSAEQSAIY
                     EVVQKIEEAEGFADLQAELPAVADAFKQVNEGKMEVAGFVDVLKTLAEETTDEEVKAAI
                     EELVEKLDGKEFVTGFDEFKVLDADKAEKNADGKYEVEISVPSITDTMENIQLVAYSKE
                     DAKKWQIVDPISVDKENKTLEVALDDGAFFTVVADAE"
     CDS             complement(1103..2137)
                     /locus_tag="ctg9_19"
                     /transl_table=11
                     /translation="MKKTAKEAARQRKIYMILIIILIIVLTVLGGGYYFMMQTKAASQR
                     TSGKNSDWQSQTSQTSGSDTVEYKGGTYRYNDHLSNYLFLGIDTRNSVDTYQTQEDAGQ
                     ADAIFVVSMDRATEEIKVLFIPRDSMTEIEVFNPSGKSLGESTDHINIQYAFGDGKQKS
                     CELMKTAVSNLLDGLPIQGYCSMNMDGIPVITDFVGGVQITVPDNSLEDTYPEFKEGAV
                     VNITGENAEKFVRYRDTEKTQSALVRQERQKTYLQALIQKAQEKAGEDAGFVADLYDSI
                     KSYTVTNMGNDVFAKLLTASGNGITDTETVPGEGKQGKNFDEYQVDKDALSDLIISMFY
                     EKIQ"
     CDS             complement(2160..3137)
                     /locus_tag="ctg9_20"
                     /transl_table=11
                     /translation="LGKVSRNKKRKGKKTNILLGFICIILVGVLGTILVMSYNTEQEEA
                     KRLTELAGNQQSGIEDYEAVKEHAAQLEKASSEDENTEDADNSETKKSKKKEDTAGEED
                     AEETAQAEDTAEAETPRTISGIACWGDDLINGEESNTYSYMAVLQKLLTDNGYNLTVIN
                     KTLQGGGTLSMMKMAGVSDETLQGYIAKHQQAANGAQLNVTETGIRDLTEEQTTRNDMD
                     CVPVIFMGYYGGWNHDPAELAEQQEQILNTFQNKDQFIVVGTRPMDGSVTSEALDQVLS
                     EKWGEHYISLANVTQQLSATYEAQQAMAEAVFQKLQELGYISQS"
     CDS             complement(3199..3906)
                     /locus_tag="ctg9_21"
                     /transl_table=11
                     /translation="MKKLNLTDKRKPDYFYSEAIKTLRTNIQLSGQSIKTILVTSCFPN
                     EGKSDVVLSLAQELGSIGKKVLLLDADIRKTAYAGRLGVEEEVKGLSQLLSGQVGLQDI
                     IYETNFPNMDIIFGGPAAPNPSGLLSENIFKVFLKEVREYYNYILIDTPPIGTVIDAAV
                     IGRCCDGAIFLIQPGSVRYRDAQKAFAQLERSGCRVLGAVMNKIDTSGDKYYSSYYKHY
                     GEYYRRSDDESQK"
     CDS             complement(3928..4740)
                     /locus_tag="ctg9_22"
                     /transl_table=11
                     /translation="MKKGKGKYQMLDNLNSKFESSRVQALDVNDDEVEIDLLEIFHALR
                     KKILLVLMVALIGGCIGAACTQFLMTPIYSSTSSMLVLSKETTLTSLADLQLGASLTSD
                     YTVLITSTPVLEQVVTNLNLDMTAEDLKEDVTINNPTDTRILEITVDNPDSTMAKKIVD
                     EIANVSSSYIGDKMEVIPPKIIEVGKIATERTSPSVMKNSVIGFLLGFLACAAIVVVYA
                     VMDDTIKTEEDIEKYLGVSVLAKVPDRKDYVNMKNKKPKSNKKNKKRR"
     CDS             complement(4917..5645)
                     /locus_tag="ctg9_23"
                     /transl_table=11
                     /translation="MLEEGIFDIHCHIVPGVDDGAADIEETRKLLEMEYKQGVRNIILT
                     PHFRFQMFETPLEKVQRQFRLAEEAAADISKDLHLYLGCEFHANMEILPMLREKKVSTM
                     AGSRYVLVEFSHNSEAPYIRERLSAMLSGGYRPIVAHIERYEATRTDLDFVEELTEMGA
                     YMQINADSIVGKDGFFTKRYCQKLMKNDLVHFVGSDCHDSSKRISRIGEAYSYVIKKMD
                     TDYAKQLFIRNPQKIIDHKF"
     CDS             complement(5747..6823)
                     /locus_tag="ctg9_24"
                     /transl_table=11
                     /translation="MSELSFEQMLEDSVKTIRNGEIVQGTVIDVKEDEIILNIGYKADG
                     IITKNEYSNDASLVLTDAVHVGDTMEAKVLKVNDGEGQVTLTYKRLAAEKGNKRLEEAF
                     ENQEVLKAPVTQVLDGGLCVNVDEARVFIPASLVSDTYEKDLSKYADQEIEFVITEFNP
                     RRRRIIGNRKQLLLAEKAEKQKELMEKIHVGDTVEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVENPKKVFTVGDKVKVLIKEINGEKIALSLKFPEANPWLTAAEDFAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISREHVAKPADVLSIGQEIEAKVVDFNGEDKK
                     ISLSMKALEAPAEEAAEE"
     CDS             complement(6804..7682)
                     /locus_tag="ctg9_25"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVDKVYELIDTEQKPIFTLGPIIHNEGV
                     VADLEARGVHVIAEADLDSPDDTLQNGTVVIRSHGVGKPIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHVIIIGDKDHPEVQGICGWCQGPYTVIKNQEEAEAFLLPEGKKI
                     SIVSQTTFNYNKFKDLVEILCKKRYDNNVLNILNILNTICNATEERQREAKNIAGEVDT
                     MLVVGGRHSSNTQKLFEICKKECGNTYYIQTPVDLDSEMFQCSSYVGITAGASTPNKII
                     EEVQEHVRIKF"
     CDS             complement(7701..8372)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_26"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.1e-77,
                     bitscore: 251.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     EAFDLDQIRKDIIERDERDMNREISPLKQAEDAVLVDSSEMGIDDVVNAILNVYKEKVQ
                     K"
     CDS             complement(8441..9889)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_27"
                     /sec_met_domain="HI0933_like (E-value: 2.2e-128, bitscore:
                     419.4, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMPVVHIYIDRSEAETWNHDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTDVQEIVKKPVTDSANTLESEATLTESGSDAGKGRKGKKSPDIPQEKITGVILTDGTF
                     MEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYIPKLQGLS
                     LKNTGLTIKNGKKVLYEDFGEMMFTHFGITGPMILSASAHIGAKLAKAPNGELSAYLDL
                     KPALTREQLDARILREFEAGPNKQFKNVIGVLFPSSLTPVMLELGGIPAEKKIHDISRE
                     ERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGEVLDL
                     DAVTGGYNLQIAWSTAYLAAQAIQ"
     CDS             complement(10001..11413)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_28"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-46, bitscore:
                     150.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.3e-58, bitscore:
                     189.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTMEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             complement(11582..12730)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_29"
                     /sec_met_domain="OAD_beta (E-value: 1.3e-156, bitscore:
                     511.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFNLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             complement(12747..13115)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 62.5; E-value:
                     8.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_30"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.3e-20, bitscore:
                     62.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGVGAVKVTASVPGKVVKVAASVGQAVKAGDSVVILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             complement(13143..13850)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_31"
                     /sec_met_domain="OAD_gamma (E-value: 2.7e-27, bitscore:
                     86.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALVIGSTSVVFAADKVDDTVKSTLVTTAEGLTDAIVQLKDEDI
                     ENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQYTVTVPLKFEKADANF
                     VYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVMLILLSLLISLFRFIPNP
                     EAKKAAEAKAAKAAKEAEAAAIAQAAPAQAEENLADDGELVAVIAAAIAAAEGTTTDGF
                     VVRSIRKVKRNRR"
     CDS             complement(13913..15349)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_32"
                     /sec_met_domain="CT_Vparvula (E-value: 2.8e-136, bitscore:
                     446.0, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVVPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKVETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
ORIGIN
        1 ataaatgcca tatttctgta taataaattc ttgtacggat ttcctatccc atgacgacaa
       61 acatatgata aaacgaatgc cagatgcagg ctgattaaat caattaatat aaaatcaaag
      121 tgcttcagcc aacctttaga actttttcta tacatatttt tctttttctt ctctccctgt
      181 tttcataaat ctatgttttc gctataggtt attctacata gttctacata atttgtcaat
      241 attttctgtt taaaacattt cgtattactg aaagcaaagc atacaataac tttttccaga
      301 gcacaaaaaa cagccgccat ttctggcggc tgcattttat ttctgaatta ccgaataatt
      361 attcagcatc tgcaacaaca gtgaagaaag caccatcatc taatgcaact tcaagagttt
      421 tgttctcttt gtcaacgctg atcggatcaa cgatctgcca tttctttgca tcttctttgc
      481 tgtaagctac aagctgaatg ttctccatag tatctgtaat acttggaaca gagatctcaa
      541 cttcatattt accatcagca ttcttctctg ctttgtctgc atcaagtact ttgaattcat
      601 caaaacctgt aacgaattct tttccgtcga gtttctcaac gagttcttcg atagcagctt
      661 ttacttcttc gtctgttgtc tcttctgcaa gagttttcag aacgtcaacg aaaccagcta
      721 cttccatttt accttcgtta acctgtttga aagcgtcagc tactgccggc agttctgcct
      781 gcagatctgc aaagccttct gcttcttcga tcttctgaac aacttcatag attgcagact
      841 gttcagcaga tactgtaatt gcgcttgtgc ggcttcctgc tgcactgaca cctacagtag
      901 cacatcctac accaagggca gttgctaaag caagtgtcat gaatttcttt gcaagtttca
      961 taatgcacct ctccttttgg attattttta tattgataat cgtacaggaa gtctgtacga
     1021 attatctctg agtaataata acagtactaa tgactattta ccaccataca atttattcca
     1081 aaccggctgt cttctaaccg gtttattgaa ttttctcata aaacatggaa ataatcaagt
     1141 ccgacagagc atctttgtct acttgatact catcaaagtt cttaccttgc tttccctcac
     1201 ctggtacagt ctctgtatca gtgataccgt ttccggatgc tgtaagcagc ttcgcaaata
     1261 catcatttcc catgtttgtg actgtatagc tcttaatact gtcatagagg tctgccacaa
     1321 atccggcatc ctctcctgcc ttctcctgcg ctttctgaat taatgcctgg agataggttt
     1381 tctgtctctc ctgacgaacc agagcactct gggtcttttc agtgtctcga tatcgtacaa
     1441 acttttctgc gttttcacct gtaatattaa caacagcacc ctctttaaat tccggatatg
     1501 tatcctcaag gctgttgtca ggcactgtga tctgaactcc acctacaaag tccgtaatca
     1561 ccggaatacc atccatattc atggagcaat atccctgaat cggcagtccg tccagcagat
     1621 tggatactgc tgtcttcatc agttcacagc ttttttgctt gccatcacca aatgcgtact
     1681 gtatattgat gtggtctgtt gactctccga gacttttacc ggatggattg aaaacttcaa
     1741 tctccgtcat agaatctctt ggaataaaga gcaccttaat ttcttctgtt gccctgtcca
     1801 tggaaaccac aaaaatcgca tctgcctgac cggcgtcttc ctgtgtctga taggtatcta
     1861 ccgaattcct tgtatcaatt cctagaaata agtagttgct gagatgatcg ttatatctat
     1921 atgtcccgcc cttatattcc acagtatcac tgccagatgt ctggctcgtc tgactctgcc
     1981 aatcactgtt cttgccactt gtcctttggg atgctgcttt tgtctgcatc ataaaataat
     2041 acccgccgcc caaaactgta agaactatga tcaggataat tatcagaatc atataaatct
     2101 ttcgttgtct cgcagcttct tttgctgttt ttttcatttt cattccttca atcgtttatt
     2161 cagctctggc tgatatagcc aagctcctgc aatttctgga acactgcctc tgccatagcc
     2221 tgctgtgctt cataagtagc agacagctgc tgtgtcacat ttgcaagact gatataatgt
     2281 tcgccccact tctcgctgag cacctgatcg agtgcttcag aagtcacgct tccatccata
     2341 gggcgtgttc ctacaacaat gaactggtct ttgttctgga atgtatttaa aatctgttcc
     2401 tgctgctcag caagctctgc aggatcatga ttccatccgc catagtatcc catgaagatg
     2461 acaggtacac agtccatatc atttctggta gtctgttctt ctgtaagatc acggattcct
     2521 gtctctgtta cattcagctg cgcaccattt gcggcctgct gatgtttcgc aatatatccc
     2581 tgaagagttt catcacttac accggccatc ttcatcatgg aaagtgtgcc gccgccctga
     2641 agggtcttgt tgatcactgt caggttatat ccgttgtctg tcagaagttt ctgaagcact
     2701 gccatgtagg aataggtgtt ggattcctca ccattgatca gatcatctcc ccagcatgcg
     2761 ataccggaaa ttgttctcgg tgtttccgct tcagcagtat cttctgcctg tgcggtctcc
     2821 tctgcatcct cttccccggc tgtgtcttct ttcttcttgc tcttctttgt ctcactgtta
     2881 tcggcatctt ctgtattctc atcttcggag gatgccttct ctaactgtgc agcgtgttcc
     2941 tttactgctt cataatcttc gattccgctc tgctggttac ctgcaagttc tgtcagacgt
     3001 ttggcttctt cctgctctgt attatagctc atcacaagaa tagtgccaag aacccccacc
     3061 aggataatac agataaaacc cagcaaaata tttgtctttt tcccttttct cttcttattt
     3121 ctgctcactt ttcccaattt tcctttactg ttaattatgg ttatgatatc acatctgaac
     3181 gattatcaga cagcgatatt atttctggga ctcatcatcg cttctgcgat agtattcacc
     3241 ataatgtttg tagtaagaag agtaatattt gtcgccactg gtgtctatct tattcataac
     3301 agctcccaga acacggcatc cgcttctctc aagctgtgca aatgccttct gtgcatctct
     3361 gtatctgacg ctgcctggct ggatcaggaa gatcgctcca tcacagcatc tgccgattac
     3421 cgcagcatcg attacagttc cgatcggcgg tgtgtcaatc agtatgtaat tgtaatattc
     3481 cctgacttct ttcagaaaaa ccttgaaaat gttctcgctg agaagtcctg aagggtttgg
     3541 tgcagccgga cctccgaata taatgtccat attcgggaaa ttcgtctcat agataatatc
     3601 ctgcagtcct acctgcccac tgagaagctg agaaagtccc ttgacctctt cttctactcc
     3661 cagtcgtcct gcataagcag tctttctgat atccgcatcc agaagaagaa ctttcttacc
     3721 gatgcttcca agctcctgtg caaggctgag tactacatca ctcttacctt cattcggaaa
     3781 acagcttgta accagaattg tctttatgct ctgaccggac agctggatat ttgtacgcag
     3841 cgttttaatc gcttcgctgt agaaatagtc cggttttctt ttatctgtta aattgagttt
     3901 cttcattgct cagattcctc cattactcta gcgacgcttc ttgttcttct tattgctctt
     3961 tggtttcttg ttcttcatgt ttacgtagtc ttttctgtca ggaaccttgg caagtacaga
     4021 aacaccgaga tatttctcaa tatcttcttc tgtcttgata gtatcatcca ttacagcgta
     4081 tacaactacg attgccgcac atgcaagaaa tccgagtaag aagccaatta ctgagttctt
     4141 cattacactt ggagaagttc tctctgtagc aatcttacca acttcgatga tcttaggcgg
     4201 aataacttcc atcttgtctc cgatatagga tgaggaaaca ttcgcaatct catctacgat
     4261 cttcttagcc attgtagaat ccggattatc aacagtgatc tcaaggatac gggtatctgt
     4321 cggattatta atcgttacat cctctttcag atcctccgct gtcatatcca ggttcagatt
     4381 tgtaactacc tgttccagta caggggtact tgtgatcagt actgtgtaat cacttgtcag
     4441 actggcacct aactgcagat ccgccagaga tgtcagcgtg gtttcctttg agagaacaag
     4501 catactggat gttgaactgt agattggtgt catcaggaac tgtgtacatg cagctccgat
     4561 gcagccacct ataagagcaa ccatcagtac cagcagaatt ttctttctga gtgcatgaaa
     4621 tatttccagt aaatcaattt caacttcatc gtcattgaca tcaagtgcct gcaccctgct
     4681 gctctcaaat ttgctgttca aattgtctaa catctgatat tttccttttc cctttttcat
     4741 tgtagttttt gtaattatcc ggctgattta ttttacagca gacagttaca gttttacata
     4801 aaccgtatac attttaccgt agtacttata aaaagtcaat tgcgagtgac attattcttt
     4861 gaaattcatt aaaattcttt aaaatccgac cacaaagtta actcggtcaa aatccattaa
     4921 aatttatgat ctatgatttt ttgcggattt cgaatgaaaa gctgtttcgc atagtctgta
     4981 tccattttct ttattacata gctataggct tccccgattc tggaaattct tttactgctg
     5041 tcatggcagt cagaacccac aaaatgaacc aggtcattct tcatcagctt ctgacagtag
     5101 cgttttgtaa aaaagccgtc ttttcccaca atgctgtctg cattgatctg catataagct
     5161 cccatctctg tcagttcttc tacaaagtcc agatctgtac gggtcgcttc gtatcgttca
     5221 atatgtgcaa caatgggtct gtacccgccg gaaagcattg ctgacaggcg ttctctgata
     5281 tagggtgcct ctgaattgtg agagaattct accagcacat acctggaacc agccatggta
     5341 gaaacttttt tctcacgaag cataggaagt atctccatat ttgcatgaaa ttcgcatccg
     5401 aggtaaagat gcagatcttt gctgatatct gctgccgcct cttctgccag acggaattgt
     5461 ctctgtactt tttccagagg tgtctcaaac atctggaaac ggaaatgagg cgtcagaata
     5521 atgtttctca ctccctgctt atattccatc tccaataatt ttcttgtttc ttcaatatcc
     5581 gcagctccgt catccactcc tggcacaatg tggcaatgta tatcgaatat tccttcttcg
     5641 agcattcttg ttatcccttc tgtcaacaaa actgccggat attcagcaag cagctttcca
     5701 tccggcagtc tctgttattc aacacaacta tttttgttgt ctgttattat tcttctgcag
     5761 cttcctcagc cggtgcctca agagctttca tgctcaggct gatcttcttg tcttctccgt
     5821 tgaagtcaac aaccttagct tcgatttcct gtccgattga cagtacatct gcaggtttgg
     5881 caacgtgctc tctggaaatc tgggatacgt gaaggagtgc atctacacca ggtgcaagct
     5941 ctacgaatgc accaaagtct gtcatacgtg caactttacc ttttactacg tttcctacag
     6001 cgaagtcctc agctgctgtg agccatggat ttgcttccgg gaatttaagg gaaagtgcaa
     6061 tcttctctcc gttgatctct ttgataagaa ctttgacttt atcgccaaca gtgaatactt
     6121 tcttcgggtt ctctactctg ccccaggaca tttcggagat gtgaagaagt ccgtctgctc
     6181 cgcccagatc gatgaatgca ccgaaatctg taacgttctt aactgttcct tcaactgtgt
     6241 caccaacatg gatcttctcc attaattctt tctgtttctc tgctttctca gcaagaagaa
     6301 gctgcttacg gttaccgatg atgcggcgtc ttctcgggtt gaattctgtg ataacgaatt
     6361 cgatctcctg atctgcatat ttggaaaggt ctttctcata tgtgtcggaa accaggcttg
     6421 caggaataaa tactcttgct tcgtctacgt ttacacaaag tccgccgtca agtacctgag
     6481 ttacaggagc ttttaatact tcctgattct caaatgcttc ttcaagacgt ttgttgcctt
     6541 tctctgctgc cagtctcttg taagtaagag taacctgacc ttctccatcg tttactttga
     6601 gaacttttgc ttccattgtg tctccaacgt gaacagcatc tgtgagtaca aggcttgcat
     6661 cgttagagta ttcgttcttt gtgataatac cgtctgcttt ataaccgata ttcagaataa
     6721 tctcatcttc ttttacatcg atgacagtac cctgtacaat ctctccattt ctgatagttt
     6781 ttacggaatc ttccagcatc tgttcaaaac ttaattctga catgttcttg aacctcctca
     6841 ataattttgt ttggggtgga agcccctgct gtaataccta cataactact gcattggaac
     6901 atttcagaat ccaagtctac aggtgtttgt atatagtaag tatttccaca ttccttttta
     6961 catatttcaa acagcttttg agtattggaa ctatgccgac cacctacgac caacatagtg
     7021 tctacctctc cggctatgtt ttttgcttct ctctgccgtt cttcggtagc attacaaata
     7081 gtgtttaaaa tattgagaat atttaaaaca ttattatcat acctcttttt gcaaagaatt
     7141 tcaactaaat ctttaaattt gttgtaatta aatgtcgtct gagacacgat gcttattttt
     7201 tttccttccg gaaggaggaa tgcttcggcc tcttcctggt ttttgatcac tgtgtaaggt
     7261 ccctggcacc atccgcagat tccctgaacc tctggatgat ctttgtcacc gataataatc
     7321 acatgatttc cggccaggct ctctttttcc acgatgcggt ggatcttcag gacgaaggga
     7381 caggtgacat ctacgtaaga gatgtttttt tctttcaatt tatcgtaaat gggtttgcct
     7441 acaccgtggg aacggatgac tactgttccg ttttgcaggg tgtcatccgg ggaatccagg
     7501 tctgcttctg cgataacatg gacgccacga gcttccagat ccgctactac gccttcgttg
     7561 tggatgatcg ggcccagagt gaaaataggt ttctgttctg tgtctatgag ctcgtagact
     7621 ttgtccactg cacgtttgac accgaagcag aagcctgctg tttctgctac ttttactttc
     7681 ataaaataat ccttcctaaa ttatttctgc actttttcct tatatacatt aagaatcgca
     7741 tttacaacat catcaattcc catttccgaa gaatctacaa gcactgcgtc ctctgcctgt
     7801 ttcagagggg agatttcgcg gttcatgtcg cgttcgtcgc gctcgatgat gtcttttcgg
     7861 atctggtcca ggtcaaaggc ttctcccttc tgttcatatt ccagtgctct tctttttgct
     7921 ctggtgtctg cgcttgctgt gaggtagatt tttacttctg cgtttggaag gatggttgtg
     7981 ccgatatctc tgccgtccat gactacgtcg tttttctctg ccagagttct ctgaagtttc
     8041 agaaggtggg ctctgacttt cgggtttgcg gaacttttgg atgccatgtt tcctacctgt
     8101 tcggtgcgga tcatagcatt tacgttctct ccgttgagga tgacaatctg ttctccgttt
     8161 ttgtattcga tggagatgtc agcgccggaa catacggctt cgatctcttc ctgattttct
     8221 ccgtttacgc catggttcag aagatataaa gccattgccc tgtacatggc tcctgtatct
     8281 acatagataa atgataattc tttcgctact ttctttgcga tggtgctctt tcctgctcct
     8341 gcaggtccgt cgatggctat gttacatccc attttcgtgg ttcctcctgt ttctattatt
     8401 taataacgta tagtcgaatc atatcataga tataatttgc ttactgtatg gcctgcgccg
     8461 ccagatatgc ggtagaccag gcaatctgta agttatatcc acctgtcact gcatccagat
     8521 ccagtacctc gcctgcgaag taaagacctg agattttctt tgattccatt gttccggggt
     8581 tgatctcttt gacagagacg ccgcctctgg tgatgatggc ttctttaaac tcacccattc
     8641 ctgtgattgt gaaggggaag gctttgataa ggtcaatgaa gtgctggcgt tcttctctgg
     8701 agatgtcgtg gattttcttc tctgcgggga ttccacccaa ttccagcatt accggagtca
     8761 gagatgacgg gaaaagtacg ccaatcacat tcttgaactg tttgtttggt cctgcttcaa
     8821 attcacgcag gatcctggca tccagttgtt ctctggtgag tgcaggcttc agatccagat
     8881 atgcggacag ttcgccgttt ggtgctttcg ccagttttgc accgatgtgg gcactggcgg
     8941 agaggatcat gggacctgtg attccgaaat gagtgaacat catctctccg aaatcctcgt
     9001 aaagtacttt ctttccattc tttatggtaa gtcctgtatt cttaagggaa agtccctgaa
     9061 gcttagggat atagtcttct ttggtcttta atggcacaag ggagggagca atgtccgtga
     9121 ctttcagtcc cagttctctt gcgaagcggt atccgtcacc tgtggaaccg gtactctgat
     9181 aagagaatcc gccggttgcc acgatgactg catcgccttc catgaaggtt ccgtctgtaa
     9241 ggatgactcc tgtgatcttc tcctgcggta tgtcaggtga tttttttcct tttctacctt
     9301 ttcctgcatc agatcctgat tctgttaatg tagcttctga ttccagggta tttgccgaat
     9361 ctgttacagg tttctttacg atttcctgca catcagtatg aagatgaatc tttgctcctg
     9421 ctttcttcag ctcacgctcc agagcgcgga tgatgtctga agaatggtca gactgtggga
     9481 atactctgtt tccacgctct accttcagag ggacacctgc tttctcaaag aactccatta
     9541 catcctgagg ggtaaatgaa tagaaactgc tgtagaggaa cttgggattg ctcatcattg
     9601 caggaaagag ttcttctgtg tcgcaggcat ttgtcacatt gcatctgcct tttcctgtga
     9661 tgaagacttt ctttcccagt ttctcgttct tctctaatat atgaacttca tgatggttac
     9721 gggctgcaaa aacccctgcc atcattccgg cggctccgcc gccgattatt ataactttgc
     9781 tcatggaata ttctcctgta tttattttac cctgcagatt gtctatttca tcatggttcc
     9841 acgtctccgc ttcgctacga tcaatataga tatgtaccac tggcatcata tacccattgg
     9901 cacattatat tcccgggtat catattcttt cataataacg caaaggagcc tgcttacgca
     9961 agctcctttt ttcgtttgaa catatttaat tactgatcaa ttatacagga tatgctccgt
    10021 tctttttgtc agctgctttc tcgtcaactt ttgttttctg agcctgacgg tatttgaaga
    10081 aatccatagc tacctgtggg aacagtgcgt atgttaatac gtcctcatcc tgttccttgt
    10141 actgagccat ttcgctctca agtttctcaa gctcgttgtc aagaaggtct gcaggacggc
    10201 aggtgatcgg tttctcatcg ccgatgcact tcttctgtac ttccggatta aacggtttta
    10261 cagttgcgcc gtattttcct aacaggatat cttttgtttc ttttgtaacc attttgtatc
    10321 tctcgcccat gagtacgttg aatacagcct gtgtaccaac gatctgggaa gacggagtaa
    10381 caagtggcgg ttcaccaagg tctttacgta cacgcggaac ttcctcgaga acatcgtaga
    10441 atttgtcttc tgcgtgctgt tctttcagct gggaagtcag gttggagagc ataccgcccg
    10501 gtacctggta cagtaaagtc ttgatgttaa caccaaggtt cttcggattg agcagtccgc
    10561 tgtcaagagc ttcgtcacgg atcggacgga agtagtcagc aatctcggag agaagtttct
    10621 gatcaaatcc tgtgtcgtat ggtgtatctt tgaatgtctc aaccataacc tctgttgcag
    10681 gctgggatgt tcccagtgca aatggagaca ttgctgtatc gatgatatcc acacctgctt
    10741 ctactgcttt taagtaagtc atggaagcta cacctgaggt gtaatgtgta tgaaggtcga
    10801 tcgggatctt aactgtttct tttaatgctg ttacaagctc tgtagctttg tttggaagga
    10861 gaagacctgc catatctttg atacagatgg aatcagcgcc catatcttca atacgttttg
    10921 caatgtctgt ccagtattcc attgtgtaag catctcctaa tgtataggaa agagctacct
    10981 gtgcatgagc cttctctttg tttgcagcgc ttactgctgt ctgaaggtta cgaaggtcat
    11041 tgagacagtc aaaaatacgg atgatgtcga ttccgtttgc agcagatttc tgtacgaagt
    11101 attctacaac gtcatctgca tatggacggt atccaaggat gttctgtcca cggaaaagca
    11161 tctgaagttt tgtgtttttg aagccgtcac gtaatttacg aagtctttcc catggatctt
    11221 cgtggaggaa acgaagggat gcatcgaatg ttgcaccacc ccagcactct actgcgtgat
    11281 agccgacttt atcaagttta tctacgatcg gaagcatctg ttctgtggtc atacgtgttg
    11341 cgatctggga ctgatgagca tcacggagaa tggtttccac aattttaaca ggttttttct
    11401 ctaattctgc cattattata tctcctttat agtttgttcg ttactgatca ttttgttctc
    11461 aataactcag ccaatattac ttcagggttc agacagttgt cataccctgt ggctctatat
    11521 cgaatagctg ttccactgct tattgcatcc gcaataaaag cagggaactc atttcattca
    11581 attatacacc gaaaatagcc atgaatgttc cagctgctac ggctgtaccg ataacaccgg
    11641 caacgttcgg acccattgcg tgcatcagaa ggaagtttgt aggatctgcc tctgcaccca
    11701 ctttctggga tacacgggct gccataggta ctgcggatac acctgcggaa ccgatcagcg
    11761 ggttgatctt tccatgagtc agtttgcaga gcagtttacc aagcatacat ccgccgaatg
    11821 taccgattgc gaatgcaaca agacctaaaa ctacgatctt cagagtatct gcgtttaaga
    11881 atgcttctgc acttgtggaa gcacctacgg atgtacccag aaggataact acgatataca
    11941 tcagggcatt ggaagctgtt tctgtcagct gttttacaac accgcactct ctgaacaggt
    12001 taccaagcat gagcatacca accagcggag ctgttgtagg caaaatcagg cagacaacga
    12061 ttgtgataac gatcgggaac aggatcttct ccagtttgga aaccgggcga agctgatcca
    12121 ttttgatctt acgttctttc tctgttgtgc agagtttcat gataggcggc tggatgatcg
    12181 gaaccagtga catataggaa tatgctgcca ctgcgatcgg tcccatcagt gcagactgtc
    12241 caagtttacc tgcaaggaaa atggaagtcg ggccgtcagc accaccgatg atggagatag
    12301 ctgctgctgc ttttccgttg aatccaagga agattgcaag gaagtaagct gcatagatac
    12361 caagctgtgc cgcagcaccc atcaggaagc tgatcgggtt tgcaatcagc ggaccgaagt
    12421 ctgtcatggc acctacaccc atgaagatca gggatggtaa gatactccac tcatcaagga
    12481 tgtagaaata atgaagaagt ccacctacac cattggacat atcttccggg tttgccataa
    12541 tgtccggata gatatttaca agcagcatac cgaatgcgat aggaacaagc agaagcggct
    12601 caaatccttt cttgatagca agataaagga atacgcaggc tactgcgatc atcaggtaat
    12661 tgccccatgt cagattgaag aatgctgtct ggtgaatcag gttggacaat gtttctgtta
    12721 cataagacat ttgactacct cccgtcttag ttcattgttg ctaaagtatc tccgttttct
    12781 acagaggcac cttctgcaac atcaatgctt gcgatagtac cgtcctgagg agctactaca
    12841 gggatttcca ttttcatgga ttcaagaata actacgctgt ctccggcttt tactgcctgt
    12901 ccaacacttg ctgctacttt gacaactttg ccaggtacgg aagcagttac ttttactgcg
    12961 ccgacacctg ctgcaggagc tgctgctttc ggagctgctg caggtgcagc cttaggtgct
    13021 gcttttggag ctgctgcagg agcggatacg cttcctgttt cttcaacagt tacttcatat
    13081 gctgtaccat ttactgtaat tgtatagctt ttcattttaa aatcctccta aataaatgac
    13141 aattatcttc tatttctttt tactttacgg atggaacgaa ctacgaagcc atctgttgta
    13201 gttccttctg ctgctgcgat ggctgctgca ataacagcta ccagctctcc gtcatctgca
    13261 aggttctctt ctgcctgtgc aggtgctgcc tgtgcgatgg ctgctgcctc tgcctctttt
    13321 gcagctttgg cagcttttgc ttctgctgct ttctttgctt ccggattcgg aatgaatctg
    13381 aacagagaaa tcagaaggct taataaaatc agcattacga atacagttcc aatacccatc
    13441 agagtattaa gacctgctct ctgaagagtc ttgcccatac catactgtac atctacagac
    13501 atggaagtcg gtgttccctg tgagtcaaag acatatacaa agtttgcatc tgctttctca
    13561 aatttaagag gaacagtaac tgtgtactga tcatctttga aagttacagt agtttcacca
    13621 ttgctgtcct tctttgcgcc aagttcatcc ttggatgtct gccaggactg catggcactt
    13681 gttgtaaagt catctcctga actcatgtaa ttctcgatgt cttcatcttt aagctggaca
    13741 atggcatctg tcagtccttc tgctgtagtt accagtgtgg acttaacagt atcatcaacc
    13801 ttatctgcgg caaataccac agaggtgctg ccgatcacca gcgcagccat tacgagaaat
    13861 gtcatgaata cagaagttat ttttttgatc attttcatat gcgtcacccc gcttagaccg
    13921 ttccatgttt cttagacgga cgatcttctc tctttgtgaa cagcatctca aatgcaccga
    13981 ttacatattt tcttgtgtca gccgggctga ttacagtgtc aacatagcct cttgctgctg
    14041 cggaagcaac accattctga agctctctgt actgagcagc tttttcattc agttcagcag
    14101 catctgcatc tgcatacatg atcttggctg ccagggaagc atccatcata ccgatctctg
    14161 cgttatccca tgcatataca aggtctgcac cgatagattt gctgttcatt gccacgtaag
    14221 ctgtaccgta agctttgccg atgatcacgt ttaccttcgg aacagttgca tctgcgaatg
    14281 cagctaccag ttcacctacg gatttcgcca tcatcttctc gctgcataag gttgccatga
    14341 agcctgttgc gtttgtaagt gtaagtaccg gaatatcaaa agcgtcgcag aatttcacga
    14401 aatctgctgc ttttcttgcg cctcttgcag agatgcttcc gtcaaatgtt tctactttct
    14461 taccttctgc gtcatatact tcgcttctgt ttgcaacagc acctactgta gcgccgttta
    14521 aacggataaa gcctgtaacc atgtcttttg catagtctgc ttttgtctcg aagaattcac
    14581 cgttgtcagc gatctgggaa agtgcgattg ctgtgtcacc tgcacagttt gcaagatctg
    14641 cgcatacgcg gttaagatca tctgtacact ctgtgtaatt gtctgtgtct tcattattag
    14701 aaggaagaag tgatactaag gaacggatct ggccaagaat ctcatcctct gtaccaacgc
    14761 catcgatcac acctgtctct ttgctctgga aatcagctgc tgctgtgtcg catttgtctg
    14821 tgttgtttcc ttccagtgcg tttggtgtgt tgacgaacat ttttcctttt ttggattcca
    14881 tgaatgtgaa atctgtcagt gacgggacaa ctgccatacc accgccgcat gttccgaaga
    14941 ttgctgtgat ctgtgggatc acaccggatg ccagtgtctg tttcagatag atctgtccga
    15001 aagcttccag tgcgtctgtt gcttcctgaa gacggatacc tgcacagtca acaagtccga
    15061 taaccggagc gcctgttttc atggcaagat cataaagtct tgtgatcttc tttgcatgca
    15121 tttcaccaac agtaccgttt aatacggatg catcctggct gtatacataa accagtttgt
    15181 catcgatcac accatatccg gtgataacac cgtcagatgg tgccttgttt gcagtcatgt
    15241 tgaaatctgt ggatctggct gttacaccct gtccgatttc gacaaaactg tttgcgtcaa
    15301 gcaaagaagt aattcttgtg cctgctaagc tttgtgttgc attactcatt cttgtttgcc
    15361 ctccatcttt atgagaatat ttaaaagtta acccaaaaat ttagccgatt ttaattttac
    15421 cttttccggc agaaaatttc aacatttatt tgtcattttc gttaaaaata tagcaaaaaa
    15481 atttgtcagg tttctccaaa ttttgttttt ttgagcattt cttcctattt aatagagggt
    15541 attacggtta ttttgtattg tcctgtattt caccctctcc cgcaaaccag tgtgtcgaca
    15601 agttgatttc tcgaacaatc ctgcgtctga atttcttatt tctatcctgc aagattgttt
    15661 caagaatcaa cttgtcggca caccagagcg tgtttgaggt aactatacct ctcacttgtc
    15721 tgcgaatccg actgcacagg tataaaagtc tcagcaaaac catagatgtt ttttattata
    15781 tagcacgaat tatcaattag atttatggat tatcccgtta tataattaac acatcaaaga
    15841 aattcaggcc acagctaaag cactgaacaa ttatatagca ctcctcgtaa ataatgcatt
    15901 taagacagtt cagcagagtg cgaaagacaa ggaagatatc tgcaggcgtg ctgacgcacg
    15961 gcaaagatat ctgacgcagg atttcacact ctgatggact ggattaaaat gcattatttt
    16021 agaggattgc tatagatcca acagaaaatt tcaggaggaa agacgtaatg aaaagcaatt
    16081 accagcatat tttcacacca ctcacagtaa aaaatatgac
//
