LOCUS       c00002_gnlPro..        13853 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DJGNELGD_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:45:04
            Original ID  :: gnl|Prokka|DJGNELGD_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 195281
            Orig. end    :: 209134
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13853
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[205281:208842](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13561
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13853
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13853
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="2"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             205..1113
                     /locus_tag="ctg2_172"
                     /transl_table=11
                     /translation="MKNIIKKITAIAMCGVLTVGWVLMTGAVSEYEDRKDFEVTGTTQK
                     ISNNQLFVTTTGYTENTAKNFGAMFISMDYQKYSVMFKDCIDAPKFVNLPKNQEFTRHM
                     ITADNRYFGNTGMKFNYDSTGGEYVKIRIKLSDYFPDVFNDDGTMTGKLSDGTYKNFDF
                     TYEDFGTDSSGKPCYATSGAYFVSGGAVTSFVPDKNGYAEFYISRQLGEDTGLMAYKYC
                     RLKNGAECKTTIGGKLNCLTCGDAYPDGNITVGDATSVQKYVVGIVEFGKTQLFNSDVN
                     HDGEISVVDATLIQKYIVGLI"
     CDS             complement(1620..2261)
                     /locus_tag="ctg2_173"
                     /transl_table=11
                     /translation="MTDMVKKYVPYAVIILLVYMLLPLVFIPGAMQKFSPVAYDFVFPI
                     TAIGCSAHYCSKHGLDFLFALIAPIIYLPSMLIYNGGFSSSTLSTNLILLVVYLVAGIF
                     GLFLGDLAFGDKRRQKEKAEQEEAEEMLLEAKRREKEELENMTSSSKKSERKAPYRQER
                     KPARRPSPAPQKTETADDDDFDYDKYLSGIDRKQDPNESEIDDILNEYGH"
     CDS             2686..4056
                     /locus_tag="ctg2_174"
                     /transl_table=11
                     /translation="MMEQVNVTLTETIKVLLDDKKFSTLRDILITMKPFDIAAVFENLQ
                     DEKMPILFRILPKELAAETFVEMDDETQEFLIHGFSDSELKEVVDELFVDDAVDLIEEM
                     PANVVKRILRQADKDMRKQINELLKYPEDSAGSIMTTEFIVLRPDMTAEMAIKRIRRTG
                     VDKETIYTCYVTDANNKLIGITTVKDLLLAEDDELVKSIMEENVISVTTLADQEQVAQM
                     FSNYNFLALPVVDNENRLVGIVTIDDAIDVIQEEATEDIEKMAAVLPSDKPYMKTSVFG
                     LYKKRAPWLLILMLSATFTSAIISSFEAVLANVLILSSFIPMITGSGGNAGSQASVSVI
                     RALSLGEIHFRSIFLVLWKEFRVSILCGITLAAANFVKLLLFDLNGQENAFMIALVISL
                     TLVGTIIMAKLVGSSLPLLASKVGFDPAVMANPLISTVCDSLSLLIYFGVAKLILHL"
     CDS             4748..5608
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_175"
                     /sec_met_domain="MTHFR (E-value: 5.2e-85, bitscore: 278.7,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFI
                     SVTYSAGGSGSKSRTCEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENI
                     LALRGDRVEGVEPQKDFTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRK
                     KVESGASHLISQLFFDNSVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGAS
                     LPAKFAKIMQKYDTRPEALRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEA
                     VSSLL"
     CDS             5605..6249
                     /locus_tag="ctg2_176"
                     /transl_table=11
                     /translation="MITLDRLNRKEAIRYLGGAGISLNYRMDVLMDECEKEILKTAEPR
                     FLYVERKAPFDDILLGNDIKKHLEGCHTAVMMCATIGSEIDKLIRISQISDMARAVVLD
                     SFASVAVEQVCQKVDEILAEKYSGKYMTFRFSPGYGDYPIEMQKEYLRILDAPRKIGLT
                     TGDSCLLVPSKSVTAILGISDNPIERRKRGCAICSMKGKCRFRRNGEHCGV"
     CDS             6242..8641
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pterin_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_177"
                     /sec_met_domain="B12-binding (E-value: 1e-20, bitscore:
                     67.5, seeds: 91, tool: rule-based-clusters)"
                     /sec_met_domain="Pterin_bind (E-value: 3.8e-41, bitscore:
                     134.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFKNFSNFSEYLNQKNFILLDGATGTLIQKSGVKYDHVPEVLNIT
                     HPELIESFHRRYIDAGSDIVYANTFGANAYKLQDSGYSVEEIIGAGVKIARKAVEGTDA
                     LVALDIGPIGQLLEPAGSMKFDEAYEYYKQQILAGKDADVIVFETMTDLYELKAAVLAA
                     KENCDKPILTTMTFERNGRTFTGVSPACAAVTLTGLGVDALGVNCSLGPDELEPVVSEM
                     SKYTNLPLVIKANAGLPDPNSNEYNIMPDKFAECVCSLLKYGVKVIGGCCGTNPDYIAK
                     IKSEVADREYQPQTKSVDTTVCSSTTVVEINGPRIIGERINPTGKKLFKQALVENNIDY
                     ILTQALSQVQGGAEILDVNVGHPEIDEKKMMVRVLKAIQSVCDVPLQIDSTKPEVIEAG
                     LRYYNGKPILNSVNGEEQSLATVLPLVKKYGASVVGLALDENGIPKTAEGRFEIAKRIV
                     ERAEAVGIDRKDVYIDCLTLTVSAEQAACRQTLEALHRVKTELGCKTCLGVSNISFGLP
                     NRELVNRTFLTMAMEQGLDLPIINPNVESMTGAVRAFRVLNGIDKNSLEFINAYNDAVP
                     AAPVKKADSNVDIFAAVYNGLKNEGAAATAKLLETTDAMQVVNEMLIPALDRVGEDFEK
                     NKIFLPQLIQSANTAQECFDVIKKHLTKTSGTPVSKGKIIVATVKGDIHDIGKNIVKVL
                     LDNYGYTVVDLGRDVDPQLIVDTAVEQNITMIGLSALMTTTLKSMEDTIRLVRECKELQ
                     NPDGSSKCTIFVGGAVLTKDYAMKIGADYYCRDAKESVDTAKLVLG"
     CDS             8751..9167
                     /locus_tag="ctg2_178"
                     /transl_table=11
                     /translation="MRGLFNRFANFMQGRYGTDKLNNALWVLLLILWFVNIFVWNRVAR
                     YIIDGIMLLIIVLICFRMFSRNIVARSAENRKFLPIYNAVTGWFKLTFKKIRDRKDYRY
                     IKCPVCKAQLRVRNKKGNHTVRCPKCGSEFNKKI"
     CDS             10001..13561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_179"
                     /sec_met_domain="PFOR_II (E-value: 3.2e-18, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.2e-81, bitscore: 265.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.7e-32, bitscore: 104.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-13, bitscore:
                     43.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-10, bitscore: 34.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.5e-06, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.3e-08, bitscore: 28.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00073, bitscore: 13.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.4e-20, bitscore: 64.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LARKMKTMDGNSAVAHVSYAFTDVAAIYPITPSSVMADLTDKFSA
                     QGAKNLFGRQVQVTEMQSEGGASGAVHGSLAAGALTTTYTASQGLLLMIPNMYKMAGEL
                     LPGVIHVSARALTSHALSIFGDHSDIYACRQTGYAMLCSNNPQECMDLAAVAHLAAIEG
                     RVPFLHFFDGFRTSHEIQKIEEWDYADLADMLNWDAVEAFRRRALNPEHPVTRGTAQND
                     DIFFQAREACNKYYDAVPEVVVKYMDKVNAKIGTDYKPFNYYGAEDAEHVIVAMGSVCD
                     CTEEVVDYLNAAGEKVGLLKVHLYRPFVADYMLRELPKTVKTISVLDRTKEPGSIGEPL
                     YLDVLAAINGSDFAGVKVYTGRYGLGSKDTTPGDIIAVYRNAESETPKRRFTIGIVDDV
                     TNLSLPIVENPDTTPKGTHSCKFWGLGADGTVGANKNSIKIIGDNTDMYAQGYFAYDSK
                     KSGGLTVSHLRFGKTPIKSTYYISKADFVACHNPSYVDKYDIVDDLKEGGSFLLNCPWD
                     TEELSERLPGKMKKILAERHINFYTIDGIKIGKEIGLGGRINTVLQSAFFKIADIIPAD
                     KAKELMKAAAKKSYMKKGQAIVDMNYAAIDRGMEDLKKVEIPADWANAVDNSVADKAEG
                     NGALVEYVNEILKPVNAYKGNKLPVSTFMDHVDGTAPNGSAAYEKRGIAVDVPEWNPEN
                     CIQCNRCAIVCPHAVIRPVAMTADELAKAPEGTKSLPMMGLKDLNFVMTVSTLDCTGCG
                     ACAQVCPGKKGAKALTMQPIDSQRPKQAVFDYALTLEDKPEVHEKFKFTTVKGSQFKQP
                     LLEFSGACAGCGETPYAKLVTQLFGDRMFIANATGCSSIWGASAPATPYTKNKKGYGPA
                     WQNSLFEDNAEFGLGMALGQKAIRNRLIEYVEGIQKDTDSADLKTACQNYLDTVTDSTS
                     SRPATDALIAELEKNTEDAKVGELVKKTLVDKDELAKKSMWIFGGDGWAYDIGFGGLDH
                     VIASGENVNILVFDTEVYSNTGGQASKATPVGSVAQFAAAGKAVKKKDLAAIAMSYGYV
                     YVAQCAMGADNNQVLKAMVEAESYNGPSLVICYAPCINHGIKGGMGIAQLEEKKAVEAG
                     YWNIFRYDPRLADEGKNPFMLDGKAPSASYRDFIMGEVRYNSLTRSFPERAEKLFEKAE
                     KVAADKYAHLEKLASLPDAE"
ORIGIN
        1 gtatattgta gggttgagtt aaataaaaat ttcatgtaaa agcaaactga cgaagtaatg
       61 gtacaatctt tttgataaga cagattatat atatgtcgcc aattacacac aacttccata
      121 acatcaactg attttgcgaa aacataaaat tcaatcaaat cgggcgtcca atgagcgccc
      181 ctactgatag aaagaggaaa aacaatgaaa aatataatta aaaaaataac tgcaatcgca
      241 atgtgcggtg tgcttaccgt cggttgggtt cttatgacag gtgcggtaag cgagtatgaa
      301 gatcgcaagg actttgaagt tacaggtaca acgcagaaaa tctcaaacaa tcagcttttt
      361 gttacaacaa cgggatatac cgaaaatacg gcaaagaatt tcggggcaat gttcatatca
      421 atggattatc aaaagtacag cgtgatgttt aaggactgta ttgatgcacc gaagtttgta
      481 aatctcccga aaaatcagga atttactcgc catatgataa cagcggataa tcgttatttt
      541 ggtaatacgg gtatgaaatt caattatgat tcaacaggcg gagaatatgt taagataagg
      601 attaaactct ccgactattt tcctgatgtc tttaatgatg atggcacaat gaccggaaaa
      661 ctcagcgatg gcacatacaa gaattttgac tttacatatg aggatttcgg tacagacagc
      721 agcggcaaac cttgctatgc aacctcgggc gcatattttg tcagcggagg tgcggtaaca
      781 tcttttgtcc ccgataagaa cggctatgcg gagttttata tttcaagaca gcttggcgag
      841 gatacgggcc ttatggctta taaatattgc agacttaaaa acggcgcaga gtgtaaaaca
      901 acgattggtg gcaaattgaa ctgcctgact tgcggtgatg catatccaga cggaaacatt
      961 acggttggag atgcaacatc tgttcagaaa tatgttgtag gtattgtaga attcggcaag
     1021 actcagcttt ttaacagcga tgtaaaccat gacggcgaaa tcagtgttgt tgacgcaacc
     1081 ttgattcaga agtatatcgt tgggttgatt taaacaaaaa taatggtaca aataatattg
     1141 taatttaaat gatataaatg ttacaaagta actgcaattc tgtatctcat ttatacagtt
     1201 tattttcatc ataaattttc tgtcattact tggcgggcgt ccaatgaacg cccctacggg
     1261 attgtgcgaa aaattgcaat gctacgctcg ggcatgatat gtttttttat attacaaact
     1321 gtctacacga atcgggaacg gcggctcgct gtgcgggaga atacggttct tccctacaaa
     1381 atcatacaca acttccataa catcacataa tcatatttaa acataaaatt taatcaaatc
     1441 gggcgtccga tgaacacccc tgctgattaa acaaaaacag tcgggaagac aatgctttgc
     1501 atttcgcaaa ttgtcttccc gactttaatt ttacattttt agttatagag ttctgctagg
     1561 gtattttatt ttcgccctta taaatactat ctgcacgaac tgggaacggc ggctcgccgt
     1621 tagtgtccgt attcgtttaa gatatcgtca atttcgcttt cgttcggatc ttgctttctg
     1681 tcaataccgg aaaggtactt gtcataatca aaatcatcgt catctgctgt ttcggttttc
     1741 tgcggtgcag gcgacggtct gcgtgcaggc ttgcgttcct gtctgtaagg tgcttttctt
     1801 tcggactttt tgcttgatga agtcatgttc tcaagttctt ccttttcacg gcgctttgcc
     1861 tcaaggagca tttcctctgc ttcttcctgt tctgcctttt ctttctgacg gcgcttgtca
     1921 ccgaaagcaa ggtcgccgag gaaaagtccg aaaattccgg caacaagata aactacgagg
     1981 agaataaggt ttgttgaaag tgtgcttgaa gaaaatccac cgttgtagat gagcatactc
     2041 ggaagataaa taatcggcgc aatgagtgca aagagaaagt caagtccgtg ttttgagcag
     2101 tagtgtgccg aacagccgat tgctgtaatc gggaacacaa agtcatatgc aacgggtgaa
     2161 aacttctgca ttgcgcccgg aataaacaca agcggcaaca gcatataaac aagcaaaatt
     2221 attaccgcat agggaacata ttttttaacc atatctgtca taacggttaa tctccaatct
     2281 ttgaaatttt attttaaatc atgcatattc attatacatt gatacacttc aaaaagcaag
     2341 aaatattata ccgagttacc aagctgttac agaggataat gtaaaatgtt tgcaaagtgg
     2401 atttttagcg gataaatccg ttgacatcgg acataaaaaa gaataaaata aatatgtacg
     2461 ggcttttgcc cgaatttaaa tgcgaatgag gtgaaaactt aatggacgca gacggtaata
     2521 aaggcgctgt acccgggcga agttgcaaca gaatgtgcgc ttgtgcgttc attttgtttt
     2581 attgattttg ctttgtatgt atttttattt taatttgaat tgatttaatt taatactcag
     2641 ggtgacaccg tctttacttc caattgaatt aaaaaggagg aaaagatgat ggaacaggtt
     2701 aacgtaaccc ttaccgaaac tatcaaagtg ttgcttgatg acaaaaagtt cagcactttg
     2761 cgtgacattt tgattacgat gaaaccgttt gacatcgcgg cggtttttga aaatctacag
     2821 gatgaaaaaa tgccgattct gtttcgtatt ctgccaaagg agcttgcggc ggaaaccttt
     2881 gtcgaaatgg atgacgaaac tcaggaattc cttatccacg gcttcagcga cagcgaactg
     2941 aaagaggttg tcgatgagtt atttgtcgat gacgccgttg accttattga ggaaatgcct
     3001 gccaatgttg taaagcgtat tttaagacag gccgacaagg atatgagaaa gcagattaac
     3061 gagcttttga aatatcccga ggacagcgct ggctcgatta tgacaaccga gtttattgtg
     3121 cttcgtcccg atatgacggc tgaaatggct attaaaagaa tcagaagaac aggtgttgac
     3181 aaggaaacaa tctacacctg ctatgtaacc gatgccaaca acaagcttat cggtattacc
     3241 accgtaaaag accttttgct tgccgaagat gacgagcttg taaagtcgat tatggaggaa
     3301 aatgttatct cggtaactac tcttgccgat caggagcagg ttgcccagat gttctcaaac
     3361 tataacttcc ttgctcttcc tgttgttgat aacgaaaacc gacttgtcgg tatcgtaaca
     3421 attgacgatg ctattgatgt tattcaggaa gaggctaccg aggatatcga aaagatggca
     3481 gccgtattgc cgtctgacaa accgtatatg aaaacaagcg ttttcggtct gtacaaaaag
     3541 agagcgccgt ggctgcttat actcatgctt tcggcaacct ttacaagtgc gattatctca
     3601 tcatttgagg ctgtgcttgc aaatgttttg attctctcat cgtttatccc gatgattacg
     3661 ggttcgggcg gtaacgcagg ttctcaggcg tcggtttccg taatccgtgc gttgtcgctc
     3721 ggtgaaattc atttcaggag cattttcctt gtgctgtgga aagaattcag ggtgtcaatt
     3781 ctttgcggta ttacccttgc ggcggcaaac tttgtaaaac tgcttttgtt tgatctcaac
     3841 ggtcaggaaa acgcatttat gattgccctt gtaatttcgc ttacgcttgt cggcacaatt
     3901 attatggcaa agcttgtcgg cagcagtctg cctcttttgg caagcaaggt cggctttgac
     3961 cctgccgtta tggcgaatcc gctcatttca acagtctgcg actcgctttc attgcttatc
     4021 tatttcggcg ttgcaaagtt gattttgcat ctgtgatttt tttaaaattg aaagttgaaa
     4081 atggaaaatt gaaaattgag gtcgggaaga cagtttgcaa aatgaaaatc attgtttccc
     4141 gaccgttttt gtttaatcag taggggcgtt cattggacgc ccgtcttgat gaaataattt
     4201 gtaagaacat aaatttttga tttgatgaaa acggtgtata gtctgtagcg gcgaaccgtg
     4261 ttcgccaatc gaaacgattg taaaatcggt tcgacttaat gcagactatt gtcagctacc
     4321 atatcatttc atactacaaa aattgtgtgt tcgttttggt tgtataacca aaacgattgg
     4381 cgaacgaggt tcgccgctac aaaatatcag taactttgtg atttttatat aatgtgattt
     4441 gacatcaaat ttgtaccatt gctaacggga gaacacggtt ctcccctaca tcatttaggt
     4501 aattgtatct catttatatg gtttattttt atcaaaaaaa ttgtgtcgtt acttgcgggc
     4561 gtccaatgaa cgcccctaca ccgtgctaca tataacaaaa ctccttgtca taactttcat
     4621 ttatatccaa atctcccaaa aaatgatagc cttaaacgac aaaacccacc aaaacagtat
     4681 tgtatgcaaa aattatttat gctataatta atcaagttta acaaaaccat taccgaggtg
     4741 tttatatatg aaaataagca atttatttaa cagcggaaaa acagtttttt cttttgaagt
     4801 atttccgcct aaaaagacct ctccgattga atcggtttac ggcaagcttg aagaaatttc
     4861 ggctttaaag cctgacttca tcagcgtaac atacagcgca ggcggcagcg gttcaaagag
     4921 ccgtacctgc gaaatcgcaa caaaaatcaa gagagatttc ggagttgaat ccgtggcaca
     4981 cctcacctgc attaacagca caaaggctga tattgaccgc aaccttgcgc tttttaaaga
     5041 gaacggcatt gagaatattc ttgcactccg tggtgacagg gttgaaggtg ttgaaccgca
     5101 gaaggatttc acttatgcaa gcgatttgtg cagatacatt gcgtcacagg gtgattttga
     5161 cattgccggc gcttgttatc ccgaggttca cagcgaggca accgatgagg ttgaggacat
     5221 tcacaacctt cgcaaaaagg ttgagtcggg tgcaagccac cttatttcac agcttttctt
     5281 tgacaactcc gtttactatc gttttcttga aagagcgaag attgcaggcg tgaatgttcc
     5341 gattgaggca ggtattatgc ctgtaacaag caaaagtcag attgaaagaa tggtttcaat
     5401 gtgcggtgca agccttcctg caaaatttgc aaagattatg cagaagtatg atacaaggcc
     5461 cgaggctttg cgtgacgcag gcattgcata tgcggttgac cagattgttg accttatcgc
     5521 acacggtgtt gacggcatcc acctctacac aatgaacaac ccgtatgttg caagaaaaat
     5581 tacggaggcg gtgtcaagtc ttttatgata acgcttgaca gattaaaccg caaagaggct
     5641 atacgctacc tcggcggtgc aggaatcagc cttaattacc gcatggatgt gctgatggat
     5701 gaatgcgaaa aagaaatatt gaaaacagca gagccgagat ttctctatgt tgaacgcaaa
     5761 gctccgtttg acgatatttt actcggcaat gatataaaaa agcatcttga gggctgccac
     5821 acagctgtta tgatgtgtgc gacaatcggt tcggaaattg acaagcttat ccgtataagt
     5881 cagatttccg atatggcaag ggcggttgtg cttgacagct ttgcaagcgt tgccgttgaa
     5941 caggtgtgtc aaaaggttga cgaaatcctt gccgaaaaat acagcggaaa gtatatgacc
     6001 ttccgtttca gccccggcta tggggactat cctattgaga tgcagaagga gtatctgaga
     6061 atacttgacg ctccgagaaa aataggtctt acaacaggtg acagctgtct gcttgtgccg
     6121 tcaaagtcgg ttacggcgat tctcggaatt tcagacaatc cgattgaacg aagaaaacga
     6181 gggtgtgcaa tttgcagtat gaaaggcaaa tgtcgcttca gaagaaatgg ggaacattgt
     6241 ggtgtttaag aatttttcaa actttagtga atatctcaac caaaagaatt ttattctgct
     6301 tgacggtgca acaggaactc tcattcaaaa aagcggtgta aagtacgacc atgtgcctga
     6361 ggtgctgaac attactcacc ccgagcttat cgagagcttt cacaggaggt atattgatgc
     6421 cggatctgac attgtgtacg caaacacctt cggtgcaaat gcctacaagc ttcaggacag
     6481 cggttacagt gttgaagaaa tcatcggtgc cggcgttaag attgcaagaa aagccgttga
     6541 gggtacagac gccctcgttg cccttgatat cggtccgata ggtcagttgc ttgaacctgc
     6601 cggttcaatg aaatttgacg aggcttatga gtattacaaa cagcagattc ttgccggtaa
     6661 agatgccgat gtcatagttt ttgaaacaat gaccgacctt tatgaactta aagccgcagt
     6721 ccttgccgca aaggaaaact gcgacaagcc tatcctcaca acaatgacct ttgagagaaa
     6781 cggacgaaca tttacgggcg tatcccctgc ctgtgcggct gtcactctta cgggactcgg
     6841 tgttgacgct ctcggtgtaa actgttcact cggtccggat gagcttgaac ccgttgtttc
     6901 cgagatgtcc aaatacacaa atcttcccct tgtaatcaag gctaacgcag gtttgcccga
     6961 tcctaacagc aacgagtaca acattatgcc cgataaattt gccgagtgcg tttgttcact
     7021 cctcaaatac ggtgttaagg ttatcggcgg atgctgcgga acgaatcccg attatattgc
     7081 aaaaattaag tcggaggttg ccgacagaga atatcagcct cagacaaaga gcgttgacac
     7141 aaccgtttgc agttcaacga cggttgttga aatcaacggt ccgagaatta tcggcgaaag
     7201 aattaacccc acaggcaaaa agctgtttaa gcaggcgctt gttgaaaata atattgatta
     7261 tatcctcact caggctctca gtcaggttca gggcggtgcg gaaattcttg atgtcaatgt
     7321 aggtcatccc gaaattgacg aaaaaaagat gatggtgcgt gttctcaagg ctattcagag
     7381 tgtgtgtgat gttccgctcc agattgactc cacgaagccc gaggttattg aggcaggact
     7441 ccgctactac aacggcaaac cgattctgaa ctccgtaaac ggtgaggaac agagccttgc
     7501 aacggttctt cctctagtca aaaagtacgg tgcgtctgtt gtcggacttg cacttgacga
     7561 aaacggtatc ccgaaaaccg ccgagggcag atttgagatt gcaaaacgaa ttgttgaaag
     7621 agccgaggct gtcggcattg acagaaaaga tgtatatatc gactgtctta ctcttacggt
     7681 ttccgcagaa caggcggctt gccgtcagac tcttgaggcc ttgcacagag taaaaacgga
     7741 acttggctgt aaaacctgtc tcggtgtatc aaacatttct ttcggacttc cgaaccgtga
     7801 gcttgtaaac agaactttcc ttacaatggc tatggaacag ggacttgatt tgccgattat
     7861 caacccgaat gttgagtcga tgacaggtgc tgtaagagca ttccgtgtgc ttaacggcat
     7921 tgacaagaac tcgcttgaat ttatcaacgc atataacgat gctgttcctg ccgcccccgt
     7981 taaaaaggca gacagcaatg ttgatatttt tgcggctgtt tataacggac ttaaaaacga
     8041 aggtgcagcc gcaaccgcaa agcttcttga aacaaccgat gcaatgcagg ttgtaaacga
     8101 aatgcttatt cctgcacttg acagagtggg tgaagatttt gaaaagaata aaatcttcct
     8161 cccacagctt atccaaagcg caaacacagc tcaggagtgc tttgatgtaa ttaaaaagca
     8221 ccttacaaag acaagcggaa ctcccgtaag caagggaaaa attattgtgg caaccgtaaa
     8281 gggcgacatt cacgatatcg gcaagaacat tgtaaaggtt cttctcgata actacggcta
     8341 cacagttgtt gacctcggtc gtgatgttga tcctcagctt attgttgata ctgccgttga
     8401 acagaatatt acaatgatag gactttcggc tcttatgaca acaaccctca agagtatgga
     8461 agacacgata aggcttgtaa gagaatgtaa ggaacttcag aatcccgacg gctcaagcaa
     8521 atgtacaata tttgtcggcg gtgcggttct tacaaaggac tacgctatga aaatcggcgc
     8581 tgactactac tgccgtgacg caaaagaaag cgttgacacg gcaaagctcg ttctcggctg
     8641 atttagtgac atatatcgtc aaatgtttat tgaatgtacg ccctgcctgt gataaaatgg
     8701 tggaaggatg atttttgtaa ttaccgcttt ttgcggaaag gatgaacttt atgcgaggat
     8761 tatttaacag attcgccaat tttatgcagg gcagatacgg cacggataag ctcaacaatg
     8821 cactctgggt gctgttgctt atactgtggt tcgtgaatat ttttgtgtgg aaccgtgttg
     8881 caagatacat cattgacgga ataatgctct tgattatcgt gcttatctgt tttcgtatgt
     8941 tctcacgcaa cattgttgca agaagtgccg aaaacagaaa atttcttccg atttacaatg
     9001 cggtaacagg ttggttcaaa ctgaccttca agaaaattcg tgaccgcaag gactaccgtt
     9061 atatcaagtg tcccgtgtgc aaggcgcagc ttcgtgttcg caacaaaaaa ggcaatcata
     9121 ctgttcgctg tccgaaatgc ggaagtgaat ttaacaaaaa aatatgaccg cagaatctgc
     9181 ggttgcaacg aaatgatttt gtgataaaac taaataaaaa caaagatttg accacaggca
     9241 gtataacagg cggcctgtgg tcttttgcag tatcgcttat gctcggcaat gtgtttcagc
     9301 agttttacaa ccttgccgat acatggatgg tcgaaaaata tgtgggcgac aatgcccttg
     9361 cggcagtcgg ctcgtcatat gatagatttt ttgtgtacgg atttaagcga agcgataaag
     9421 catttataaa ttaaaaatta cggcgagccg ccgttcccaa tttgtgaaaa cagtttgtaa
     9481 atgtcaaaaa acaaattatg cccgagcgaa aggtttaatt aaatgtaaaa ttgaaaattg
     9541 aaaatggaaa attaatgtcg ggcagacagt ttgtaatgta aaaaacaaat tatgcccgag
     9601 cgtagcattg caattgttcg cccctacaga ttatacactg cttttattgt ataaaaagct
     9661 atgtgtataa acataaatat tcatcaagcg ggcggataat atccgaccca acaaataacc
     9721 aaaacctttg ttattgattt ttaaaaaatt aacaacaagg tattttgaca ggaacaagta
     9781 aatataaaaa acttttttgt aaaaaacgaa acaaaaatat atatcctgct ttgaatttct
     9841 tgtgtaaaac actttacaaa tcggtgttta agtgataaaa tttaagatga tacaaagtat
     9901 ccgtaccgct tgttgattta cggtgcgtaa ttaacgggta tcgaaaattt atgcggcatc
     9961 atttcctttg ccgctttgat taaaaaggag gacgattcca ttggcaagaa aaatgaaaac
    10021 tatggatggt aacagcgcag tagctcatgt ttcttatgcg tttaccgatg ttgcggctat
    10081 ctatcctatt acaccttctt ccgtaatggc tgaccttacc gacaagttct cggcacaggg
    10141 tgccaagaac cttttcggca gacaggttca ggtaacggaa atgcagtcgg agggcggcgc
    10201 atcaggtgct gttcacggct cactcgcagc aggtgctttg accacaactt acacagcatc
    10261 acagggcctg ctccttatga ttccgaatat gtacaagatg gcaggcgagc tccttccggg
    10321 cgttattcat gtatcagccc gtgcgctcac aagccacgca ctttctattt ttggtgacca
    10381 ctcagatatc tacgcttgcc gtcagacagg ttatgctatg ctttgttcaa acaatcctca
    10441 ggaatgtatg gatcttgccg ctgttgctca ccttgcagct attgaaggca gagttccttt
    10501 ccttcatttc tttgacggtt tcagaacttc tcacgaaatt cagaagattg aggagtggga
    10561 ttacgcagac ctcgccgata tgcttaactg ggatgcagtt gaggctttcc gtcgtcgtgc
    10621 tcttaaccct gagcatcctg taacaagagg tactgctcag aacgacgata tcttcttcca
    10681 ggcaagagaa gcttgtaaca agtattatga cgcagttccc gaagttgttg ttaagtacat
    10741 ggacaaggtt aatgctaaaa tcggcactga ctacaagccg ttcaactact acggtgcaga
    10801 ggatgcagag catgttatcg ttgctatggg ttctgtttgt gactgtacgg aagaagttgt
    10861 tgattacctc aatgccgcag gcgaaaaggt cggtcttctt aaagttcacc tttacagacc
    10921 tttcgttgcc gactatatgc tcagagagct tcctaagact gttaagacaa tctctgttct
    10981 tgacagaaca aaggaacccg gttcaatcgg cgaacctctt tatcttgatg ttctcgccgc
    11041 tatcaacggt tcggactttg caggtgtaaa ggtttacaca ggcagatacg gtcttggctc
    11101 aaaggataca acacccggtg acatcattgc tgtttacaga aacgctgaaa gcgaaacacc
    11161 taagagaaga tttacaatcg gcattgttga tgatgttaca aatctctcac ttccgatcgt
    11221 tgaaaatccc gatacaactc cgaagggtac acacagctgt aagttctggg gtcttggtgc
    11281 tgacggtact gtcggtgcta acaagaactc aatcaagatt atcggcgata acaccgatat
    11341 gtacgctcag ggctactttg catatgactc aaagaagtcg ggcggtctta cagtttctca
    11401 ccttcgtttc ggtaaaactc ccattaagtc aacatactac atttcaaagg cagactttgt
    11461 tgcctgtcac aatccgtctt atgttgacaa gtacgatatt gttgatgacc ttaaagaagg
    11521 cggttcattc cttcttaact gcccatggga tacagaagag ctttccgagc gtctccctgg
    11581 taagatgaag aagattctcg ctgaaagaca catcaacttc tacacaattg acggtatcaa
    11641 gatcggtaag gaaatcggtc ttggcggtcg tatcaacacg gttcttcagt cagcattctt
    11701 caagattgca gatatcattc ctgccgacaa ggctaaggag cttatgaagg ctgctgctaa
    11761 gaagtcatac atgaagaaag gtcaggctat cgtagatatg aactacgccg ctatcgaccg
    11821 tggtatggaa gacctcaaaa aggttgaaat tcctgctgat tgggctaacg ctgttgataa
    11881 ttcagttgcc gacaaggcag agggtaacgg cgctctcgtt gagtatgtaa acgaaatcct
    11941 caagcctgta aatgcgtata agggtaacaa gctccctgtt tcaacattta tggatcatgt
    12001 tgacggtact gctcctaacg gttctgccgc ttatgaaaag agaggtatcg cagttgatgt
    12061 tcccgaatgg aatcctgaaa actgtattca gtgtaacaga tgtgcaatcg tatgtcctca
    12121 cgctgtaatc cgtcctgttg ccatgacagc cgatgagctt gcaaaagctc ccgagggtac
    12181 aaagagcctc ccgatgatgg gactcaagga cctcaacttt gtaatgacag tttcaacact
    12241 cgactgtacg ggttgcggcg cttgtgctca ggtttgtccg ggtaagaagg gcgctaaggc
    12301 tctcacaatg cagccaatcg actcacagcg tcctaagcag gcagtatttg actacgctct
    12361 cacacttgaa gataagcctg aagttcacga gaagttcaag ttcactacag ttaagggcag
    12421 tcagttcaaa cagccgttgc ttgaattctc aggcgcttgc gcaggctgcg gtgaaacacc
    12481 gtatgcaaag cttgttacac agctttttgg tgacagaatg ttcattgcta acgcaacagg
    12541 ctgttcatca atttggggtg catctgctcc tgcaacacct tatacaaaga ataagaaggg
    12601 ttacggtcct gcttggcaga actcactctt tgaagataac gcagagtttg gtcttggtat
    12661 ggctctcggt cagaaggcta tccgcaacag acttatcgag tatgttgagg gtattcagaa
    12721 ggatacagac agcgctgacc tcaagacagc ttgtcagaac tatctcgaca cagtaacaga
    12781 ttcaacttca agccgtcctg caacagacgc tcttatcgct gaactcgaaa agaacacaga
    12841 ggatgcaaag gttggcgaac ttgttaagaa aacactcgtt gacaaggacg aacttgctaa
    12901 gaagtcaatg tggatcttcg gcggtgacgg ttgggcttac gatatcggtt tcggcggtct
    12961 tgaccatgta atcgcatcag gcgaaaatgt taatatcctc gtattcgata ctgaggttta
    13021 ttctaacaca ggcggtcagg cttcaaaggc tactcctgta ggttcggttg cacagtttgc
    13081 cgccgcaggt aaggctgtta agaagaaaga ccttgccgct attgcaatga gctacggcta
    13141 tgtttatgtt gcacagtgcg ctatgggtgc tgacaacaat caggttctca aggctatggt
    13201 tgaggctgaa agctacaacg gtccgtcact cgtaatctgc tacgctccgt gtatcaacca
    13261 cggtatcaag ggtggcatgg gcattgctca gcttgaggag aagaaggctg ttgaggctgg
    13321 ttactggaac atcttccgtt atgatcctcg tcttgcagac gaaggaaaga atccgttcat
    13381 gcttgacggt aaagctcctt ctgcatcata tcgtgacttc atcatgggcg aagttcgtta
    13441 taactcactc actcgttcat tccccgaaag agcagaaaaa ctctttgaaa aggctgaaaa
    13501 ggttgctgct gataagtatg ctcaccttga aaagcttgca agccttcccg atgccgaata
    13561 attttggcta aagcttgcac aaagtgaata tgtgaataaa taaaaaattc tcccgaatat
    13621 ggcatttgcc gtgttcggga gattcttttt aaattgaaaa tgtaaaatgg aaagtggaaa
    13681 attgtagcgg cgttcagtga acgccaatcg aaccgattgc aaaatcggtt cgaccacagg
    13741 caacggcagt attttttcgt ttaaataata atttataaat gtaaacccgt aggggcgctc
    13801 attgtgtcaa gtgcaacatg gtaaccacct gtgcaaggac atggtataca aat
//
