LOCUS       c00017_gnlPro..        16247 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DJGNELGD_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:45:04
            Original ID  :: gnl|Prokka|DJGNELGD_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16247
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16247
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3254:6247]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3255..6247
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16247
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16247
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(491..1678)
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAAT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1855..2379
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="MAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSPTEFI
                     LGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEMPVKY
                     VIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRDEGEE
                     KTFAYIRSMKK"
     CDS             2524..2988
                     /locus_tag="ctg17_3"
                     /transl_table=11
                     /translation="MIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQELLEISAIV
                     HDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVGHHHTYGNID
                     TLPYRILVESDFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP"
     CDS             3255..5492
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="Gly_radical (E-value: 4e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-271, bitscore:
                     893.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5492..6247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="Radical_SAM (E-value: 2.8e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIEPPTKERVKNAEMILNGEKTRD"
     CDS             6792..7010
                     /locus_tag="ctg17_6"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(7322..8473)
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENSMEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFRGN"
     CDS             complement(8489..9673)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2.2e-37,
                     bitscore: 119.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 6.6e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVKLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIKLV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFSVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             complement(9688..11451)
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     NSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             complement(11627..12706)
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFAIKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGINREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGG"
     CDS             complement(12706..13620)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-30, bitscore:
                     98.0, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             complement(13644..15188)
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKKKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKDNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             complement(15212..16036)
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="MVYKIMYPPIPNMGDLLNKDMLEELFNIKVVRKDLKSCNLIAIGS
                     ALDHIMYSTYPRIRAKQKIEHFMNDNVHIWSTGFIRGNAELDLGLMFRHIHIHALRGRL
                     SLQRMENILGKKLDVPTGDGGLLAERWLGFYPEKKYRVGIIPHFKEQDHPVVKKLLDNY
                     ENSTLIDLKENPKKVVEKIGECEYIISSSLHGMIVADSFHIPNMHITLTNNMFGDGNKY
                     NDYLSAFDITHTPFDCSNGDMPTISDVKNNYRIDPDVVELKKEQLFNAFPKF"
ORIGIN
        1 aaaactgtat actatgtctt tgcactgttg tatactatgt tactacactg cacacatcgg
       61 ccgcccgcct tgatgaaata ttttgtttaa tcatatatgt tttgatgtga ttataattgt
      121 gtattgaacc ttgcacgcat tgcgtgcaat cgtatgcgtt gcatacgaac gggcgaacac
      181 ggttccccct aaaacataca ttgcaaaaat aattggaatg ttatacttgg tcaaaatatg
      241 tatgttgctg tgtggttgat ttggctttgc aaccaaatca aatggcggtc actgaccgcc
      301 gctactgtat gtacaaacaa ttgctatgtt atgctcgggc aacatttgta atttactatt
      361 aaaaccgtct gcacgaacac acgaacataa aaaatgcggt ggcacattgc caaccgcatt
      421 tttattttac attttcaatt ttccactttc aatttaaaag ctccgctcgg agaacagtgg
      481 cgcaccatgt ttattgcacc gttaccgtaa tcgttacgct tgatgttctt ttaagcacat
      541 cggtgactga atatgttacc ttgtacttgc cttttcgggt ggttactaca ttgccgaaaa
      601 cttcgatatt cgatgttatg tcgttgccgc aggtgtcaac ggctgttact cctgcaaggg
      661 cgtaaaattc gccgccgctt ttgattgtgt aatcgtttgc accgctgatt attggtgttg
      721 ctttggcata cgggcatttt ttattgctgt ctgtcggatc ccatttgttg gtaaaatcgg
      781 tgattttgat tgcatccggt tttccgagag ggcctgcatt ttctgcgtcg tcatatatgc
      841 ttacatttgt gcctgtgggg cagttgtcat aaacccactt tgcatccgaa accgcaagtc
      901 ttacgcatcc ttgtgacgcc tgttcgccaa gcttgttgaa ctcctcaagc tccaaatctt
      961 cttcgctcat tgagtagtag ggaacggagt ggaaaagata atcgccagaa attccgctga
     1021 tgtatcttcc gaaaacatcg cccacaaggg aaagccattc ggacttgatt ccgattgtgt
     1081 agtcacccgt gattgtcgaa ttgtcaagac ctgtggagca aatcatcgcc cttacgggga
     1141 ttgtgtactt gcccttttcg tcatatgtgt aaaccgtcac gcagtttgcc gtgcggttga
     1201 ccttgattgc gtacaggttt tttgccgtgt tacgcttatt gttttcaagc ttgtcaagat
     1261 ttgccgttat acaggttgag tagctttgct gttttttcgt ggttgatttt gccaccgtaa
     1321 cctgaaattc cgactttgat ttgtcttttg aaatggcaga aatcagagcc gtaccctctt
     1381 tgagagcgtc aacccttccg ccgtcatcaa cggtaacaat tttactgtcc gagcttgtcc
     1441 atttggtaac ggattttgct ttttcggatg acagttcaat aagctttgat tcgcctactt
     1501 ttaatgtgag cgaatcgacc ttgctcggaa atgtcatatt ttcggttgct gccgtatcgg
     1561 gcgtctgcgg ttttggagaa ttttgagaat catttccgaa aattcccgtc acaccgcata
     1621 atatgcaggt tgcaatgagg acaacacaaa gtaaaagaat gaaaattttc tttttcatag
     1681 attacctatc cttatagaat ttaacattaa atggttacaa aattttaacc tttgtatatt
     1741 ataacttttt ttcgacaatc ttgcaagtgc tattttaaat cggcgagaaa tgtggtaaaa
     1801 tgtcagtcgg agaatgtttt gtattttcca aactaacaat ttatggtgat aattatggca
     1861 catccgatta aacatttcag aacaataacc cgtcataggc acaaggtaat tgccaactgt
     1921 gcaagggcgg gaattctcag acagggatta atacacgatt tgtcaaagta ttcgcctaca
     1981 gaatttattc tgggtgcaaa gtatttccag ggcacgagaa gtcccaatga aaaggaaaga
     2041 gaactgtacg gctattcaca ggcgtggatg catcacaagg gcagaaaccg tcaccattac
     2101 gaatactgga acgattataa cccaaagaca aagcagattg aaaatgttga aatgcctgta
     2161 aaatatgtta tcgaaatgtt ctgcgaccga gttgccgcaa gcaaaatcta caacggcaaa
     2221 aattacacgg acggcgctcc gtttacatat ttttgcagaa tcagaggcaa acaccgtatg
     2281 caccccaaca ccgaggcttt gcttgaaaaa ttattggtta tgctgagaga tgagggtgaa
     2341 gaaaagacct ttgcatatat aagaagtatg aaaaagtgat tgtttgtgcg aatcctcccg
     2401 tctgaaatat agtcgcaagg ctacccctac agaattgcac aaacaaaaac tatctacacg
     2461 aatagggtac ggcggctcgc cgtaaggagt gataatatga aaaccgacag ggttataact
     2521 gctatgattg aatattttgg aagtgacaag aaaaggattc accattttct caaggtttat
     2581 tcattcgcaa agacaatcgg tgaaagtgaa aatcttttgc ccgacgatca ggagcttctt
     2641 gaaatctccg caatcgttca cgacatcggc ataaaggtga gcgaagaaaa gtacaattcg
     2701 tctgcaggaa agtatcagga acttgaaggt cctcacgagg ctgaaaagtt gcttgccgct
     2761 ctcggttacg aaaaaacatt tattgacaaa gtttgttacc ttgtgggaca ccatcacacc
     2821 tatggaaata ttgatacttt gccgtaccga attttggtag agtcagactt ccttgtgaac
     2881 ctttatgagg acgattcaag ccgcagtgca gcagagcagg catatgacaa aatattccgc
     2941 acaaatacag gaaaaaatct gctgaaaata atgttcctca taccctaaaa ttgtactcat
     3001 ttaccatagt gttttgagcg tgaaaaagtg gtgtaaaaag tatcccaaaa tgcttgacaa
     3061 cgcccttaaa aagtgttatt ttaatggtgt tggttatatg attataaaag tgaataaatg
     3121 acagaataca aggatgtatg acgatttttt caaggagctg accttaccgg gcgtctgctt
     3181 ggaattgagt cggcattttt ttgtgtcata tacaaaattc agtattaatt atcattatcg
     3241 gaggttttac agtaatgaga gaagaatgga caaattttgc aggtggcaaa tgggagtccg
     3301 acattgatgt cagagacttc attcagagaa actacacacc ttatgacggc gaccagtctt
     3361 tccttgaagg tcctacagaa gctacagaca agctctgggg cgagctcaag gaactccaga
     3421 aggaagaaag agccaagggc ggcgttcttg atatggaaac tgaggttgta agcggcatca
     3481 cagcttacgg cgctgcatat cttgataaag accttgaaaa ggttgtaggt cttcagacag
     3541 acaagcctct caagcgtgca tttatgcctt acggcggtat caaaatggct gagcagtcat
     3601 gccagatgta tggctacact ccaagcccta aactccacga aatctttaca aaatatcaca
     3661 agactcacaa ccagggtgta ttcgatatct acactcccga gatgaagctt gcccgtcaca
     3721 acaagattct tacaggtctt cccgacacat acggcagagg cagaatcgtc ggtgactaca
     3781 gaagagttgc tctttacggt attgaccgtc ttatcgaagg caagaaagag gactttgcag
     3841 aaacaaaccg tcagggtatg agaagaggcg acttccagct tcgtgaagaa atcgctgatc
     3901 agattcgtgc tcttaacgat atgaaggaaa tggcactttc ttacggcttt gatatttcac
     3961 agcctgctaa gaatgccgca gaagcagttc agtggctcta tttcggctat cttgctgcta
     4021 tcaagactca gaacggcgct gcaatgagcg ttggtcgtgt atcaacattc ctcgacatct
     4081 acatcgagcg tgaccttgag aacggtacac ttacagaatc acaggctcag gaacttgttg
     4141 accactttgt tatgaagtgc cgtatggtta agtttgcaag aattgagtct tacaaccagc
     4201 tcttctcggg cgaccctgta tgggctacac tcgaagttgc aggtcttggc attgacggcc
     4261 gttcaatggt tacaaagaac gactaccgtt tcctccacac acttgagaat atgggacctt
     4321 cacctgagcc aaacctcaca gttctttatt cttcaagact tccggagaac ttcaagaagt
     4381 atgctgctca tatttcagtt acaacaagct caattcagta cgagaatgat gatgtaatgc
     4441 gtcctgtatg gggcgatgat tactcaatct gctgctgcgt atccgcaaca cagacaggta
     4501 aggaaatcca gttcttcggc gcaagagcta accttgctaa gtgccttctc tacgctatca
     4561 acggcggtat tgatgaaaag acaaagatgc aggttggtcc tgaatataca cctatcacat
     4621 cagagtacct tgattatgac gaagttatca agaagtatga cacaatgatg gattggcttg
     4681 ctcacctcta tgtaggcaca cttaacatga ttcactacat gcatgataag tactactatg
     4741 aggcagcaga aatggctctt atcgatacag atgtaagaag aacatttgca acaggtattg
     4801 caggcttctc acatgttgtt gactcactca gcgctattaa gtacgctaag gttaaggtta
     4861 tccgtgacga ggacggcatt gctgttgact ttgaaacaga gggcgacttc ccaagatacg
     4921 gtaacaatga cgagagagca gataagattg ccgttgatct tctcaagaca ttcatggcta
     4981 agctcaagta ttgccacaca tacagagatt cagagcctac aacttctatc cttacaatca
     5041 catcaaatgt tgtttacggt aaggctacag gttcacttcc tgacggcaga aaagcaggcg
     5101 aaccactttc acctggtgct aacccaagct acggtgcaga gcagaacggt cttcttgctt
     5161 cacttaactc tgttgctaag cttccttacg agtacgctct tgacggtatt tcaaatactc
     5221 agacaatcaa cccgggtgct ctcggacaca acgatgacga gcgtgttgac aacctcgtaa
     5281 atgttatgga cggctacttt gatcagggcg cacaccacct caatgtaaat gtattcggta
     5341 cagaaaaact cattgacgct atggagcatc ctgagaagga agagtatgct aacttcacaa
     5401 tccgtgtatc gggttatgct gttaagttca tcgaccttac aagagagcag cagctggatg
     5461 ttattgccag aacctgccac gacagaatgt gatgtcggac aacgctgtta aaggctttgt
     5521 acactcaata gaaacttttg gctctgttga cggtccgggt gtgagatttg tgatttttct
     5581 gagcggttgc gcaatgcgtt gccagttctg ccacaatccc gacacctgga aacacgatga
     5641 aaacaccgtg gaatataccg ccgacgagtt gcttaataaa gcgcttgcat accgccccta
     5701 ttggaaaaat aagggcggta tcacagtaag cggaggtgag ccgcttttac agattgactt
     5761 tttgcttgat ttgttcaaga aggctaaaaa gcagggcgtt aatacctgta ttgacacaag
     5821 cgccaacccg tttacaacca aagagccgtt ctattcaaag tggaaagagc taatggaata
     5881 tacggatttg ctgttgcttg atataaagca tatcgacaac gaacagcaca aaatccttac
     5941 aggacagcca aacaccaata ttcttgaaat ggcaagacag ctttccgata tgggcaagcc
     6001 cgtatggata agacatgttc ttgtgcctga aagaaatgat aaggacgagt atcttttcag
     6061 acttgccgac tttatccgtt cgctcaagaa tgttgagcgt gtagaggtgc ttccgtatca
     6121 cacactcggt gtgtacaagt ggaaggctct cggttatgac tatcctctcg agggcattga
     6181 gcccccgaca aaagagcgtg ttaagaatgc ggaaatgatt cttaacggcg aaaaaacaag
     6241 agattaattt cttatataac aacggcagta ccgatttttt ggtactgccg tttttgtttt
     6301 gatttttatt tgttattctg cttttgttgt tttttcttca gcaaaattga tgaatcaaag
     6361 gtgtattcaa agatttttaa gccgtccttg ttgagaaatc gtcaccgtcg gaagaatcga
     6421 ccgctactca ggaacagact gttcagactg ctccgacggg tgagcctgca actgtcggta
     6481 caatctctgc aaatccgact tcggcaacag gcagtgccgc aacatcggac agcactcctt
     6541 cacagcctga taaaaacggc agtgttcaga caggagtgac agcaacggct gttatgatgc
     6601 ttgttgtaat ttcgggcgga gtgctttttg cccttgcaga gcgtaaaaag agaatataac
     6661 acactgacag ccatttgtgc aaagattatc agttgcctat tgaaaaattt gtaaaaatga
     6721 tataaaatag caataagtag aaaaatacgg tttttccgct gatttatatt aatactgaaa
     6781 gaggtgccgg aatggataaa aacaaaaaat tattctacac aatcatcggt gcaatctctg
     6841 cacttgcggc tgccacagca gcatttctcg ctttaaaaaa gcacagatgc gcagaacaga
     6901 agcttattga ggaaattgac gatattgttt ccgaaaaaga gcctgaggag gctgcaaagg
     6961 aagaaccgca ggcagaagtt acagccgatg agcttgctga ggaagaataa gcaacaagtt
     7021 gttgcaccca attcgggtag cagtatttgc atatgcaaaa gttaaatacc cgagcggtgc
     7081 tttcaattaa gaattgaaag ttgaaaacag ataatgatgt cggcggtgtg ccaccgcagt
     7141 ctattcaaga aaacagttta aaaaagaaaa atgcatcagt tgcccgaaaa gctctgatgc
     7201 atttttgttt tgtgcgaagt aaccgccaaa cccacagccg tgaggcatta taaaaacgca
     7261 gacatcatct gatatctgct atacctcctc aatggcttgt cggttaaagc aaccgtaagc
     7321 cttaattccc tctgaattta agataaatgg catagacagc ctttttaatt ttttgaattg
     7381 gcgtaagctt gaaacccttc tttttcataa gactgagaat ttctgcataa tagtccttgt
     7441 tctgatgttt gagaacatag tccatatatt tgttcttgtc tctgtaaaat ttcggaatat
     7501 caaaaacatt cttatacagt tcaagttttc cgagtgccat aagctcaaat tgcgttctga
     7561 cgcacttttc acagtgaccg cagttgttct caccgtagta acacacattg aggttatcat
     7621 atgtaatcgg aaattttgaa atgaagtcaa ccttttcaag cctagtcttt tcaagccctg
     7681 taatgtaaaa atcggtactt tcggtactca gcatacttgc cgtaaatgcc tcatagtgtg
     7741 ccgagccggt gtcgcattgt tttatcgaaa aactgcttat cgggtatccc gacgcatagt
     7801 aatagttttt gaaaaatttc tgcatacata agaccgccga aaagctgcaa taatgatgaa
     7861 cctttacata cggcagggta agatgttcac cgagatttga attaatgtca atcaacggca
     7921 tatcaaagat ttttgcggat ttttttgcaa tttcaagacg attttcgtac agctcggcag
     7981 attgttcggg tgtgtaatta gccgtactcc tgtgggagcc gacattgaaa aaggtaagat
     8041 gactcagctt ttccatgctg ttttcggaaa gactgcaaat tgtgtcaaat gaatccacac
     8101 ctctcgaaaa tcctgttgcc gatgcatttt tgcagcagta gttttcctgt gtaagctctt
     8161 ttgcagatat cgaaattttg ttgaataatt ttgaattttt tgtaagaacg ggaatgaaaa
     8221 tttcattaag ctgaaaacac agttgcttcg acatctttgc ttctgccgaa atattcagac
     8281 tgttgttcat tgcatacggc aacagcgcaa caacgaatgc gtcggcactt tcggtcagat
     8341 agtcagcata ctttgcatca acatcaaacc agagagtgta ggaaggcttt ccgttttcgc
     8401 tgatttttga acagagtctg gcacgattat caagtttttc aattttcggt ttgccgataa
     8461 tcaatgtttc catactttta ccctcaaatt aatctctgaa aaacaaatct cttgtgtaaa
     8521 ccttttcttt tacacagtca aggacggagc tgtatctgtt tgcaacgatt acatccgatt
     8581 ttgtgacgaa cttttcaaag tcgttttcaa cgctaaagcc ctcgaataaa tcgactttaa
     8641 gtgtcggttc gtagataatt aactcgatac cgttattttt caaaagctcc ataacgctct
     8701 gaattgagct ttgtctgaag ttatcggaat ttgacttcat tgtaaggcgg taaattccga
     8761 cagcttttgg atttttattc attatctgtg atgtaataaa ttcttttctt gtcttgttag
     8821 atgttacaac agcgctgatt atgtcgttcg gaacatccga aaaattggcc ttgagctgtt
     8881 ttgtgtcctt tggcagacag taaccgccgt agccaaagga cggattgttg tagtgatttc
     8941 cgattctcgg atcaagacac acaccgtcaa tgatactttt agtgttaagg ttcttcattt
     9001 cggcatatgt gtcaagctcg ttgaaaaagc tgacacgcat tgcaaggtat gtatttgcaa
     9061 aaagctttac cgcttctgcc tctgtgtagt ccataaagag agtgtctatg ttttccttaa
     9121 ttgcacagtc tgcaagtgcc gttgcaaaag tctcggcaga ttttttcagt tcttcatttg
     9181 ccatatcaac accgacaatg attcttgacg gatagaggtt atcatagaga gccttgccct
     9241 cacgcaaaaa ttcgggactg aaaaggattt ttgtgtattt gtatttttca ataacacttt
     9301 ttgtgtatcc aaccggtata gtggatttga taactataac cgcatttggg ttgcattcaa
     9361 ttacaagctt aattacagcc tcaacggacg atgtatcaaa aaagtgtctt tcgtcatcgt
     9421 aattggtagg agtagagata attacaaaat cagcattttt gtacgcagat tttgcatcga
     9481 cggttgcaac caaatttaat tttttgtcag caagatattc ttcgatttcc ctgtcggcaa
     9541 tcggagattt cttttcattg attaacttta ccttgctttc aactacatca acagcggtta
     9601 cctcgtgttt ctgcgaaaga agtacagcgt ttgaaagacc cacataccct gtcccggcaa
     9661 ttgctatttt catttggttt cacctgatta cttttttaat aatttttttg ccttttgaat
     9721 ctgtgacgga ctgagaattg actttgcttt ttccatcatc ttgagcttca ttccgccaaa
     9781 tttcattctg ttgtcatgaa aaagcctgtt aataagcttt gcgtcctctt ccatatcggt
     9841 gaaaatctca acaaaaatcg gtcggtcgga ttcttctgcg agtgtgggaa taatgttgtc
     9901 aacttcttcc ttggttgttg cgctgtaata gtcatatccg agtgattcaa tccagccctt
     9961 tgcgcccttg tgatgttcgg cgcagatgta ctgattgatt gtaggaatct tttccttgcc
    10021 cataaagaag tgaaattctg aaccgccgcc gttgttgaga agaataattc tcgcattgtt
    10081 cttgattcct ctgatgcctg cggagttcat atcatagaag aaactgaggt cgcccacaac
    10141 gcaaaaggca agctcgtctg ttgccgatgc ctgtccgaaa aacgaagaca tacagccgtc
    10201 aatacccaga gcgccgatat tgctgtaaac cttgacattc ggtttcaaat cgaagaactg
    10261 catagttctt gtactgctga gaattgcaag gtgcagaaca gaacggtcgg gaataatttc
    10321 agcaagcttt ttggcaacat acatatttga gaacggaaga ttgcttgaat aatcaagcat
    10381 tttgatatcg tcattccaca tattgtagta tgtcatatca ttttttgaat tctgcggtgc
    10441 gttctctgca aagcagttaa agaaatactg cggtgtacat tcaaatacat ctgtcagctt
    10501 gtcggaaaaa tctctgattc ttcccgcagt atcaatttgc cagtgaacaa atttttcctt
    10561 gtgagcctta atcataggct tgagtttata tgaagcaata ttgttgccga acgaaataat
    10621 aagatcgggg cataactcgc cgaacattcc ctgcattgag cattctgaca aaggataggt
    10681 cataaggcag cccttgcact tgaggtttga catatgctca accgatataa ggcaattgta
    10741 tttctcaaag aacttctcga cgcacgctct gtcatcttcc gagaaacagt tgttctgacc
    10801 ggcaatgaca agaattttct tatattttga aagcctttct gcatattcac gccacttctc
    10861 ggagggcata tcgggagaaa ttctgttgat tttcctaacc tgaggaagat tttcacaatc
    10921 atatacagcc gagttttcaa caatcggaat attgatatgc acaggtcctg ttccgtgatg
    10981 gtcaagctcc gaaagagcct cgttaataag tctttcgcag taccatctgt catttccgcc
    11041 acgcacaacg ggaagattaa cggatttttt tgtaaccgat tcaaaaatat tgacctgctg
    11101 ggttttctgc agcataagct gatttaatct gtacgggtct ttgtcagcgg taattgcgac
    11161 aatcggaaca tcctgataaa atgcctctgt catacccgga agatagttgc ttacagccgt
    11221 acccgaggta cagatacagg caacggggga ttttgtctgc tgtgcaagtc cgatgccgta
    11281 atacacggca cttctctcgt caacgaccga atgacactca aaaaaatcgt cattttcaag
    11341 tgaatgaatt ataggaatat cactgcctcc gggagaaagc accaatttgt tgatattata
    11401 ttttttcaga agtgcagtga gcaactgaat gctttttatt gtagaataca tacgctttcc
    11461 tccgctttag tttttgataa ttccggaacc gcctgtaatc agagcggttt tgccgtcaag
    11521 aatattgttg ttctccttct gcacatacac gggaacaaca ttttttgctt taaaggtttt
    11581 gattatgccc tgtctgactt tttttagtgt atttttaaga ctcattttaa ccaccgctga
    11641 caaaggattt aagataatcc aaagatatta ttgtctggtt cttgattttt tcgttcacat
    11701 cgtaccagtt tatttcggtt tctcggcagt ttccgtcaac aatttcacgg ttgattccaa
    11761 gacttttcaa aagaccttcg gagcggatgt ttcttccgct tttgttcttg aattcaacaa
    11821 aaagattctt gttgaaaata acagaaaacg ctgttccgtg aaacgagttt gtaacaacat
    11881 attcggcatt tttgaaacag ccgacaaatt cctcaacagt aggtgcaaca atataattta
    11941 taccgtgact tacagggtga ggtgcatcgt ttatgcagta aacgggaagg ttcttttctt
    12001 ttgacagttt aatggcaaaa tccacaagcg aaactgccgg attagccgta aaaatgagga
    12061 tatacggttt gtcaattttt gaaacggcaa tctttttcca ttcgtctgcc gaaatcagca
    12121 gggtaggatc aagatgagtt tcggcggttc tgcccgtgag ttcttttaca agcttttctc
    12181 cgctcggttc acgaactgag aacttctgaa aaccgttcag ccttttttta tattcatcaa
    12241 taaattcatc gggcaatgtc ggaacggcaa agcttgccgc atatgaatac ttctgtttgt
    12301 catcggcaaa tgtcagaaaa taagcgggat caaaaccgac gcatctcgga ctccacacct
    12361 gatcgcttcc cgaaatgaac aagtcataat cgtttttaag ctctccgata ttctgcggag
    12421 tatacgactt tttactcttt acaagatagt tattgaaaaa cgacttaaaa gcgtctctgc
    12481 gttttgctct tcttcttacc atgacacagc tttttgcaaa ggatttcaga aggtcgtttt
    12541 tataaatgcg aaagggtttg tagtcggctg tgattttcgg acagatatag tcaacaattt
    12601 cacactccgc accgagcgag gaaacggttt tttgcaacgc atagctttga agcacagcgc
    12661 cgtagttcaa tgcacggtga aatgttacaa tgcctacctt tttcattatc tgcttccccc
    12721 tgattgtttt ttgtacaaaa aatatcccat gggataaaat atgaccgcaa gagccctctt
    12781 tgaaaatgtg tcgggcatct tttttatttc ggaaaatctt ttaccgttga gtaagccgtc
    12841 acgagaaagt cccacaaatt gtttgataaa gaacttagga ttgctctttg cgtaatccca
    12901 acattcgttt ataaagtgga gtcttacgaa aatagtttcc ctgtgagccg agtaagcgtt
    12961 gcctgtcaaa gaattttcct gatcgtttat gtaatatcgc aacggtgtgt caataaaacg
    13021 ggttatatac tttcttccga tattgtccca atagatattt tcgggataaa aatgaagtcc
    13081 cgaaacacac ggatatgggt tggctctgat tatttcaagt tttgtcattc cccacatctc
    13141 accgtcaatt ttatacttca atctcaggtc aaggtcggaa cagtcaaatc gttctgacgg
    13201 cagaggacaa ccgtttgttt tgccgctttc gttacaggtg cggcacgaaa ttcccttgta
    13261 ttttgacctg tcttcatcgg gaattttgtt ccattcgttt ataaatgttt caagggcatc
    13321 gtcttttacg ctgtcatcgg agtcaatcgt tataaagaat tcaccctttg caatctgtgc
    13381 cgcaacattt gttgcaatgt gttttccttt gttggtctga tatttatagg ttatgttaaa
    13441 gtcgggtctg tcgctgatga atttctcaac cgtttctttt gtgttgtcgg ctgaaccgtc
    13501 atcaacaatt atccattcaa aatttctgta tgtctgtctt ttcagcgcct catataatct
    13561 gggcagagtt tttgccctgt tatatgacgg tgtaaaaacg gaaaaagtat attcagtcat
    13621 tgcaacctca aaatgataat aatttagctt ttcttaaact tcttcttaat tttatccttg
    13681 ataagaacga gttcttttct tgagaaaatg agcggaacgg aaacggcata tcctgccagt
    13741 ccgcttgctg cacagagaag aaggaatgac atccagctgt ttgcgtgtac aaagctgttg
    13801 ataaagatga acatggtgat aacaacagca aagcagaacc atcctctgaa aatagacctg
    13861 taatatgttg taagctttat tttcaaaata tgtgcggcgt ataacggaac aaatactatc
    13921 gctttaagac cgataaaaac agagctgacg cctgcaatag cataaacgcc gagcggtgta
    13981 aagtgtatga gcagtaaaac gataataacc gtaagaacac cgcacacaag cgagataaga
    14041 acggaggcct tgagcttgtt gcatacggtg aaaaggctag aaagagttct tgtgtgacag
    14101 gtaaataggt atgaaataca tacaagcacc gacaaaatct gaattatggt aatttcgtcc
    14161 ggagatttgg tcggctgcca caatgtatag aacttgttgc caaacgcaat aaatcccgca
    14221 agaggtgcag tcatgagaaa actcataatc tttgacgaaa actttgtttc ttcaacaagt
    14281 aagtccgtgt tgtcctttgc ataaaggatt gtaaatctgg gagtgaagat atttgcaatg
    14341 gttgtaataa ggttatcaat gcagtgcgga acggtgtttg caatcgacaa aagtcccatg
    14401 agtcccgctc cgagagtcag gttacagatt aacaggtcaa gacctctgtt cagagctgtg
    14461 ctgagataac cgattgacga ccaaattcct gcggaaataa gaacttttac cagcttgaaa
    14521 ctgaaaaggt tgaagttcat ctttacttca ggcagaattt ttttcttgac tttgatattg
    14581 gtaagcaaaa gaaaaattcc gcttgcaagt gacgccatag cgagaaaata tacttttgcg
    14641 ggaaaaaacg agaacaaaat tactacaagc aagagcttga gcgtgtttga cgcaatatca
    14701 cggagggaat tgatatacag cttgtttttt acaaatgccg cagtagtaaa tattgccgtg
    14761 ataacgctga ttataaatgt tgcaaaagtg agcgcaaaca atatctttac gctgtcaaca
    14821 agattttcgg gaacattcag tataaattca atgttgaatg taataattga cgaaaccaaa
    14881 agtaaaacgc cggcaataat caggtcggca accaaaaccg agctgaaata tcttgacgcc
    14941 ttgtcaatgt ttcctttgct gtattcaatt gaaataaatc tgcccgacat tgagttgaga
    15001 gcagatgtta caatggtggc atactggaca aagttgtttg caagtccgat aaatccgtag
    15061 gtttcagaac cgagttcctt tacaagatag ggtgcaagaa caaagttaat tcctgttcct
    15121 atcaaaaaag acactatggc ggcaaccata tttattgcca tttgtttact tgttgataat
    15181 tttttcataa tatgacctta gttttaactg attaaaattt tggaaaagca ttgaagagct
    15241 gttctttctt cagttcaaca acatccggat cgattctgta attatttttc acatcgctga
    15301 ttgtaggcat atcgccgttt gaacaatcaa agggtgtgtg tgtaatgtca aaggcagaga
    15361 ggtaatcatt gtacttgttt ccgtcaccga acatattgtt cgtaagggtt atgtgcatat
    15421 tgggaatgtg gaaactgtca gcaacaatca taccgtgaag gctgcttgaa ataatgtatt
    15481 cgcactcgcc tattttttcg acaacctttt ttgggttttc tttcaggtca ataagcgttg
    15541 aattttcgta gttatcaaga agttttttca caacagggtg atcctgttcc ttaaagtgcg
    15601 ggataattcc gacacgatac tttttttcgg gataaaatcc aagccacctt tcggcaagaa
    15661 gtcctccgtc acctgtcggc acatcaagct ttttgccgag aatattttcc attctctgca
    15721 atgaaagtct gcccctcaga gcgtgtatat gtatatgcct gaacatcagc cccaaatcaa
    15781 gctcggcatt gcctcggata aagcccgtac tccatatgtg gacattatca ttcataaaat
    15841 gctcaatttt ctgctttgct ctgatcctcg gatatgttga gtacattatg tggtcaagtg
    15901 cagaaccgat tgcaatcagg ttacagcttt taaggtcttt tcttacaacc ttgatgttaa
    15961 acagttcttc aagcatatct ttattaagaa gatctcccat attcggaatc gggggataca
    16021 ttatcttata taccattgta ttttctccgt tgtattattt gcgccgtgag cagaagctct
    16081 gattaagaga tataaatatc ggatttgtct tgcatatgta tatcagcgaa taagtaataa
    16141 gcatccatat cgatgttgtt gcccatggtt cggtggaaat cagaagtttt ggaagtgtta
    16201 cgcacacaag cgtacagcac aacgcaaatt ctgacttatc tttgatt
//
