LOCUS       c00102_gnlPro..        15161 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNGJGJMG_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:42:29
            Original ID  :: gnl|Prokka|CNGJGJMG_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15161
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15161
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1681:11551]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1682..11551
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..15161
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15161
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..1097
                     /locus_tag="ctg102_1"
                     /transl_table=11
                     /translation="ESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQLFAAEA
                     TGPTHDKVHPRIGVTAKWIWTIYLGLTIAEIILLIAGGMDFFDSVCHSLTTAATGGYST
                     KQNSIAFFNSPYIEYVITLFMFLSGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFF
                     TLFTTVTLIFTSPFSIEESFRKAIFQVVSLQTTTGFISADYMTWVPVLWTLMCIIMLFG
                     ACAGSTTGGIKCIRIAIMSRISKNEFKHIIHPNAILPVRINHQVVSSTTKSAVLAFIFL
                     YMAIIFIGWLVLMLFGVGFEEAYSVVISSLGNVGPGIGKCGPSYSWSGLPDAAKWTSAI
                     LMLIGRLELFTVLLLFMPSFWKKH"
     CDS             1201..1578
                     /locus_tag="ctg102_2"
                     /transl_table=11
                     /translation="MNNMLRYVVYILLFLLFTITVDQDHYTVEPTDLHPQTSCYQQQQD
                     PCKRTVDFLFTNNFADMPQIAISLDNPSTSKFKCIVRILTALSELKKQELQTNHIVCHT
                     FHSLYTDAVDYYIYALRRIII"
     CDS             1682..2032
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_3"
                     /sec_met_domain="Oxidored_q4 (E-value: 3.9e-40, bitscore:
                     126.4, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYFTLLVVVILTAIALVAVALGIARAISPRSYNSQKGEAYECGIP
                     TRGRSWMQFKVGYYLFAILFLMFDVETVFLFPWAVVVQDLGVYGLFSILFFLVILVLGL
                     AYAWKKGALEWK"
     CDS             2023..2619
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_4"
                     /sec_met_domain="Oxidored_q6 (E-value: 6e-26, bitscore:
                     81.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVKKPTIKSIPYEDFKNNEYLENMVKQLNESGTKVLVGCLDDLI
                     NWGRSNSLWPLTFATSCCGIEFMAVGAARYDFARFGFEVARASPRQADMIMVAGTITHK
                     MAPVLKRLYDQMADPKYVIAVGGCAISGGPFKKSYHVLNGVDKILPVDVYIPGCPPRPE
                     ALLYGMIQLQRKVKLEKFFGGVNRKENEPQNPEQA"
     CDS             2616..4175
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_5"
                     /sec_met_domain="Complex1_30kDa (E-value: 9.4e-39,
                     bitscore: 123.1, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 1.4e-64,
                     bitscore: 208.0, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVY
                     HLEDTKTRENIVVSTRTTNREKPELPSVSDIWKGAEFNEREVYDYYGIRFIGHPDMRRL
                     FLRDDWVGYPLRKDYDENLNPLRMTNEEAVDTTQYIEVQHDGSVIEKRETIFDEDEYII
                     NIGPQHPATHGVLRFRVSLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDY
                     LGAHQNRHALCMCIEQAMGVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAF
                     FYGFRDREKILDIFEATTGGRLIQNYNTIGGVQADIAPDFVQKVKEFIAYLRPMLKEYH
                     EVFTGNVIAQERLKGVGVLSREDAISFGATGGTGRASGWACDVRKRHPYAMYGKIDFRE
                     IVHTEGDCFARYMVRMEEILESMNIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEG
                     SRGEFGVYLESHGDKFPYRMKFRATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDI
                     DR"
     CDS             4299..5375
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_6"
                     /sec_met_domain="NADHdh (E-value: 9.7e-121, bitscore:
                     392.8, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAI
                     IMIFMERKVCAAFQCRLGPMRVGPQGTIQVFADVFKMLIKEIITIRHADKFLYNLAPYI
                     VILASIMAFSCLPINKGMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIGAMR
                     SGAQMISYELSVGLSILTIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAG
                     NAEVNRGPFDLPEAESELTAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMP
                     LHIPGLDGFNAIMDYIPGFIWFFGKSFFVVWLLMWIKWTFPRLRIDQILTLEWKYLVPI
                     GLCNLLLMVIIVVFKLHF"
     CDS             5375..5827
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_7"
                     /sec_met_domain="Fer4_7 (E-value: 4.2e-14, bitscore: 43.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.9e-09, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.9e-06, bitscore: 16.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEKHSYIKGLLHGIGTLLTGMKVTGREFFTPKVTEQYPENRAT
                     LKISPRFRGRLIMPVDENGNNKCIACGLCQMACPNDTITITSESVTNEETGKKKKILVK
                     YEYDLGACMFCQLCVNACPHDAIRFDTEFENAVFDRSKLVLTLNKK"
     CDS             5843..6346
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_8"
                     /sec_met_domain="Oxidored_q3 (E-value: 5e-35, bitscore:
                     110.6, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLQLIVFIVLALFIAICSVLAVTTSRILRAATYLLFVLFGTAGI
                     YFQLNYSFLGAVQLLIYAGGITVLYVFSILLTSSQGDKAERLKNGKMVAGAISTIAGLA
                     ICLFVMLKNEFLPSHFVHGELDVRTIGHALMGMEKYQYILPFEVISVLLLACIVGGILI
                     ARKR"
     CDS             6361..6660
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_9"
                     /sec_met_domain="Oxidored_q2 (E-value: 5.7e-22, bitscore:
                     67.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYYLVVSTFMMFAGIYGFFTRRNLLAMLISVELILNSVDINFAV
                     FNRYLFPEELEGFFFALFAIGVSAAETAVAIAIIINIYRNVRNIQVKNLNEMKN"
     CDS             6663..8564
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_10"
                     /sec_met_domain="Proton_antipo_N (E-value: 2.7e-26,
                     bitscore: 81.8, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 2e-82, bitscore:
                     266.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHTILILILPFLSFLILGLAGMRMKNGLAGAIGTVSLAGVALLS
                     YLTAFNYFAGGRTAEGVYPTLTPYNFEWLPFTTNLHIDMGIMLDPISVMMLVVISTVSL
                     MVHIYSFGYMKGEKGFQRYYAFLSLFTMSMLGLVVATNIFQMYVFWELVGVSSYLLIGF
                     YYTKKEAIAASKKAFIVTRFADLGFLIGILIYGYYAETFSFTPQLQVLAVAGSMIPLAL
                     GLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIGYAP
                     EVLHWIAYIGAFTAFYAASVACAQSDIKRVLAFSTISQIGFMIVALGVCTSMNPHEGGL
                     GYMASMFHLFTHAMFKALLFLGAGCIIHAVHSNEMSAMGGLHKYMPVTHWTFLIACLAI
                     SGIWPFSGFFSKDEILTACFQFSPVIGWIMTGIAAMTAFYMFRLYYCIFWNGEWKGHSH
                     ESGLGAHTPHEAPLTMTFPLMFLAAITCVAGFIPFGNLISSNGEAYTIHLDMQIAATSI
                     IIAIASIALATWMYAGKKQPVANYLAHTFPRLHTAAYHRFYMDEIWLFVTKKIIFRCIS
                     TPIAWWDRHVIDQFFNFTAWSTHATADEIRDMQSGNVQQYSIWFLAGALILTLILLI"
     CDS             8618..10099
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_11"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.2e-69,
                     bitscore: 224.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILSFFIIVPLLMLASLWASRSINQVRGVMVVGSSILLALSVYL
                     TIDYIELRQAGATGEMLFTASTVWYAPLHICYSVGVDGISVAMLLLSSIIVFTGTFASW
                     KLQPLTKEYFMWFTLLSVGVFGFFVSTDLFTMFMFYEVALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIFYGAGGETMNLLEIAKLHIPHEMQRIFFPLIFLGFGVL
                     GALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRVAMYLMPEGAAMWGDVFLIL
                     TTISVVYGAFSAVVQTDLKYINAYSSVSHCGLVLFALLMMTRTSCTGAILQMLSHGLMT
                     ALFFALIGMIYGRTHTRDVRLMGGLMKIMPFLAVGYVIAGLANLGLPGLSGFVAEMTVF
                     VGSFQNDDTFHRVCTLVATTSIVITAVYILRVVGKILYGKVLNPEHLKLTDATWDERVA
                     VICLIACVAGLGLAPFWISDLISNSVEPIISQLLN"
     CDS             10130..11551
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_12"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.9e-72,
                     bitscore: 233.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDITAILHMHAELSLTAVFILMFLLDLFLPAPQRHWLRPMACIL
                     LTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTIGTILVFLQADPWLKREDTRHKQG
                     EFYILTLSTLLGMYFMVSAGHFLLFFLGLELATIPMACLVAFDKYKGHSAEAGAKFILS
                     ALFSSGIFLYGISMIYGTTGTLYFEDIPAELTGTPLQVLALVFFFSGLAFKLSLVPFHL
                     WTADTYQGAPTTVSAYLSVISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIA
                     NLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQGMASLVYYIVVYIAANLAVFGVIN
                     TIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSG
                     YYLIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFALG
                     IISGVYQLLSDTSIL"
     CDS             11723..12949
                     /locus_tag="ctg102_13"
                     /transl_table=11
                     /translation="MKKVLYITILACSTLWVSCTEKNKQSVRTDSFIEKNVAFARAQIG
                     NEIRIIEKSEKFTNPVTLKTDSTIYYCDYADWRSGFFPGSVWYLYELSGDTTLLSLADK
                     YTSAIEEAKKLTWHHDVGFMINCSFGNGWRTTKVPRYKEVMIEAARSLATRFREKPGII
                     QSWDVTRGWQSERGWECPVIIDNMMNLELLFEATKLSGDSTFYHIAVNHADRTLKEHFR
                     TNGSCYHVIDYSLADGMVRHRQTAQGYADESTWSRGQAWAIYGYTVCYRETHDKKYLNQ
                     ALKTFQFMKTHPRLPKDLIPYWDMDAPNIPNEPRDASSASCIASALYEISTMDVPDANS
                     YKIYADSIMASLASPNYLASLGKNGNFLLMHSVGSIPHGTEIDVPLNYADYYFLEALKR
                     KRDIEEGTR"
     CDS             complement(12950..13354)
                     /locus_tag="ctg102_14"
                     /transl_table=11
                     /translation="MDKVERWSRVGIIYHLELPEGEIFVSTNELYLSLVIENLLDNANK
                     FTDSGSITLKMRLDKAQSKLRIEVTDTGCGIPPEKREEIFLCFIKLDEFAQGNGLGLYL
                     SRLIIKRLSGNIFVDSSYTEGTRMVICLSV"
     CDS             complement(13375..13608)
                     /locus_tag="ctg102_15"
                     /transl_table=11
                     /translation="MEKVLGELNQKAGESEKMKTAFINSMCHEIRTPLNAIVGFSGIIT
                     ANAEILTSLIDHLLVVANLDSSDAPLLCEQTR"
     CDS             complement(13593..13994)
                     /locus_tag="ctg102_16"
                     /transl_table=11
                     /translation="MNNYYLYKHSFHNALITNDSLIKYAWMTSQSNVPGLLDINSQIYE
                     AMEDNKNAFKYHKLYIQVQDSIKSSNLKKQLSELQVKYEVDQLNHENYRLETKNRRILV
                     ITLFMVLVLVMSICFYLYYDLKKDRWKKF"
     CDS             complement(14204..14881)
                     /locus_tag="ctg102_17"
                     /transl_table=11
                     /translation="LLYTDICLGIFVVIGSSISTTKDSLLNIIGSPVEFSLQIEIYRGL
                     ADFYFEKPEEVDYLNKMYFTAKAVNDKTHMFETLSDLVFSYIKVYHADSVWYYMSLLKD
                     VGTLEESHPYLFFLRMRLFAGRVRNNEVETAITEELAFMGKENIGGNDIYIQMEQTFIT
                     GYALCSEGKYEEADPYLETAYKLACQLPYEEGFKFRICTVWNFLSTLNFIDKGDLYIEY
                     VEK"
     CDS             15082..15159
                     /locus_tag="ctg102_18"
                     /transl_table=11
                     /translation="MVKKLVSVFCICAYFGLAHAQIPQEI"
ORIGIN
        1 tagagtcatt gccacacggg cttttgttct ggcgaagtat gacacaatgg atcggcggat
       61 taggaattgt atttttcact attgccgtat taccgatctt cggagtgggc agtgtacaat
      121 tatttgctgc tgaagccacc ggccccaccc atgataaagt acatccgcgt attggtgtta
      181 cagccaaatg gatctggact atctatctag gactgaccat tgccgagatt attctgttga
      241 ttgccggagg tatggacttt ttcgacagtg tatgtcattc tctgaccact gccgccacag
      301 gagggtattc aaccaaacaa aacagtattg cattctttaa ttctccttat atagaatatg
      361 ttattacctt gttcatgttc ttgtcgggca ttaatttcac cttgttatat ttattattct
      421 taaaaggaaa ttttaaacgc ttattccaaa acacagaact ccactggtat ttgggaacag
      481 tgggattttt tacacttttc actaccgtca ctcttatttt caccagtccg ttcagtattg
      541 aggaatcttt ccgtaaagcc atatttcagg ttgtttcctt acaaaccact accggattca
      601 tttctgcaga ttatatgacc tgggtacctg tactttggac attaatgtgc atcatcatgt
      661 tgttcggagc ttgtgccgga tccactacag gaggaataaa atgtatacgt atagccatta
      721 tgagccgtat ttctaaaaat gaattcaaac atatcattca tcccaatgct atacttcctg
      781 tacgtatcaa ccaccaagtt gtttcatcaa caaccaagtc agcagtactt gcattcattt
      841 ttctatatat ggcaattatt tttattggat ggctggttct tatgctgttt ggagtaggat
      901 ttgaagaagc ttacagcgta gtcatttcca gtttgggcaa tgtaggccca ggtattggaa
      961 aatgcggtcc gtcctattca tggagcggat tgccggatgc agcaaaatgg acaagcgcaa
     1021 tactgatgct aatagggcgt ttggagttat ttaccgtact tctgctcttt atgccgagtt
     1081 tttggaaaaa gcactgacat tcacttccta taaccatttt tatacataaa taattcaaaa
     1141 aatctcaatg aagcttcaaa taattggcta tctttgcacc ctcattaaaa gggtaacaag
     1201 atgaataata tgttgagata cgttgtatat atcctattat ttctactgtt tacgataaca
     1261 gtagatcagg atcattatac ggttgaaccg acagatctac acccacagac atcttgttac
     1321 cagcaacaac aagacccttg caaaagaaca gtggatttcc tgtttaccaa caattttgca
     1381 gatatgccac aaatagccat atcacttgac aacccttcca catcaaagtt taaatgtata
     1441 gtccgcattt taacagcatt gagcgaactt aaaaagcaag agctacaaac aaaccatata
     1501 gtttgccaca cctttcattc gctttacact gatgccgtag attattatat ctatgcactc
     1561 cggcggatca tcatttaatt tttaattttt tttcagcatt tcgctgagta gaaatcctta
     1621 taacaaacgt cttataagga ctatttttct atccgtttgt ctaatcaaaa aaagtttaga
     1681 tatgtatttt acattattag ttgtcgttat cttgacggca atcgcattag ttgccgtagc
     1741 attggggatt gcccgtgcca tttctccccg ttcatacaac tcacaaaagg gagaagccta
     1801 cgaatgtggt attcctacac ggggacggtc gtggatgcaa ttcaaagtag gttactatct
     1861 atttgctatc ctcttcctga tgttcgatgt ggaaacagta tttttattcc cttgggctgt
     1921 agtggtacaa gacctaggag tgtacggtct gtttagcatc cttttctttt tagttatatt
     1981 agttttaggt ctggcgtatg cctggaagaa aggagcgttg gaatggaagt aaagaaacca
     2041 accataaagt ctattcctta tgaagacttc aaaaacaatg agtatttgga aaacatggtc
     2101 aagcagctca atgaaagcgg tacaaaagta ttggtgggct gtttggacga cctcatcaac
     2161 tggggacgca gcaattcgtt gtggccgctt acatttgcaa ccagttgttg tggaattgag
     2221 tttatggcag tgggggctgc ccggtatgat ttcgcccgct tcgggtttga agtagcccgt
     2281 gccagtccgc gccaggcaga tatgatcatg gtagcaggaa ctatcacaca caagatggct
     2341 ccggtactaa aacgtttgta tgaccaaatg gcggatccta aatacgttat tgcagtaggc
     2401 ggatgcgcca ttagcggcgg tccttttaaa aaatcatatc acgtattgaa cggagtagat
     2461 aaaattcttc ccgttgacgt atatattcct ggatgtccgc cacggcctga agccttgtta
     2521 tacggcatga tacaattgca acgtaaagta aaactggaaa aattctttgg cggagtgaac
     2581 cgcaaagaaa atgaaccaca aaatcccgaa caagcatgag tgaaaaaata gaaatacctg
     2641 ccgaaaagct acatgaagaa atgctgaaat tgcggcaggg taaacatatg gattttctac
     2701 gcagccttac cggaatggac tggggcgaag aaggactagg tgtagtctat catctggaag
     2761 atacgaagac aagagaaaac atagtggtca gcactcgcac aaccaaccga gaaaaaccgg
     2821 agcttcctag tgtaagtgat atttggaaag gtgctgaatt caatgaacgc gaagtatacg
     2881 actattatgg tatccgcttt ataggacatc ctgatatgcg ccgtttgttc ctgcgtgatg
     2941 actgggtagg ctatccattg cgtaaggact acgatgaaaa cctcaaccca ctccgtatga
     3001 ccaatgagga ggctgtagat acaacacaat atatagaggt gcaacatgat ggcagtgtaa
     3061 tagaaaaacg agaaaccatt tttgatgagg acgaatatat cattaacata ggtcctcaac
     3121 atccggcaac ccacggtgta cttcgttttc gcgtttcact ggaaggcgaa attatcaaga
     3181 aactggatgt acactgcgga tacatacatc gaggtatcga aaagatgtgc gaaagtctta
     3241 cctatcccca gaccttggcc ctgaccgacc gtttggatta tttaggtgcg caccagaacc
     3301 gccatgctct ttgtatgtgc attgaacagg caatgggcgt agaagtaagc gaacgggtac
     3361 aatacatccg taccattatg gacgaattgc aacgtataga ctctcacttg cttttcttct
     3421 cctgtctctg tatggatatg ggtgccttga ccgcattctt ctatggattc cgtgatcgtg
     3481 aaaagatact ggatatcttc gaagcaacta ccggaggacg tctgatacag aactataaca
     3541 ccattggagg agtacaagct gatatcgctc cggattttgt acagaaagta aaagaattca
     3601 ttgcttatct gcgtccgatg ctaaaagaat accatgaagt attcactgga aatgtcattg
     3661 cccaagaacg tttgaaaggt gtgggagttc tttcacggga agacgctatc tctttcggag
     3721 caacaggagg tacaggacgt gccagcggtt gggcatgcga tgtccgcaag cgtcatccct
     3781 atgcgatgta tggcaagata gattttagag aaattgtcca caccgaaggc gactgttttg
     3841 cacgttacat ggtccgtatg gaagaaatac tggaaagtat gaacatcatc gagcaactga
     3901 tagacaatat tcctgaaggg aactatcagg aaaagatgaa accgattata cgcgtgcccg
     3961 aaggaaatta ttatgccgcc gtggaaggtt ctcgcggaga attcggggtt tatctggaaa
     4021 gtcatggaga caaatttcct taccgcatga aattccgcgc taccggttta cctttagtat
     4081 cagcaatgga aactatgtgc cgcaatgcaa aaattgccga cttaattgct attggtggaa
     4141 cggtggatta tgtagtaccg gatattgacc gataataatg tgccaattct tcaatatact
     4201 acttgaagaa tgcattattt atcagactga gaattaacaa attaaataat tacaagtttg
     4261 cctattggca aattagcaaa ttgacacatt attaaattat gttcgatttt agtatagtca
     4321 cccaatgggt acactcactg ctcacgtcat ttatgcctga agaactggca gtgctcatag
     4381 aatgtatagt aattggcgta tgtatcatgt tggcatacgc agttattgct atcattatga
     4441 ttttcatgga acgtaaagtg tgcgccgctt tccaatgccg cttgggtcca atgcgtgtag
     4501 gtccccaagg taccatacag gtatttgccg atgtattcaa gatgttgatt aaggaaatta
     4561 tcaccatccg acatgctgac aagttcctgt acaatttggc accttacatt gttatcctcg
     4621 cctctatcat ggctttcagt tgcctaccca tcaacaaggg catggaggtc cttgatttca
     4681 atgtaggtat tttcttctta ttggcagcat ccagtatcgg cgtagtaggt attttgctgg
     4741 caggttggag ttccaataac aaatattcat taatcggagc catgagaagt ggcgctcaaa
     4801 tgattagtta tgaattatct gtaggattaa gcatccttac tattgtaatc ttaacagata
     4861 ccatgcaact aagcgaaatt gtagaacgcc aagctgacgg ctggttcctt tttaaaggac
     4921 atatacctgc attgatcgct tttatcattt atctgatagc cggaaatgca gaagtcaacc
     4981 gcggaccgtt tgacttgcct gaagcggaaa gtgaactgac cgccggatat cataccgaat
     5041 attccggtat gcacttcggc ttgttctatg tggcagaatt tgtaaacttg tttatcatcg
     5101 ccgcagtagc cacaaccatc tttctaggag gatggatgcc gctacatatt cctggactag
     5161 acggattcaa tgccattatg gattatattc ccggatttat ttggttcttt ggcaagtcat
     5221 tctttgtagt atggttatta atgtggatca aatggacatt tccccgtctg cgtattgacc
     5281 aaattctaac actggaatgg aaatacttgg tcccaatagg tttgtgcaac ctgctgttga
     5341 tggtaattat tgttgtattt aaattacatt tctgatgaaa gaagaaaaac attcctatat
     5401 aaaaggacta cttcatggca tcggtacatt acttaccggt atgaaagtga caggacgaga
     5461 gtttttcact cctaaagtca ctgaacaata tcccgaaaac cgtgccacat taaaaatatc
     5521 gccccgtttc cgaggacggc ttatcatgcc ggttgatgag aatggtaata acaaatgtat
     5581 tgcttgcgga ctttgccaaa tggcttgccc caatgataca atcaccatta ccagcgaatc
     5641 tgtgaccaac gaagaaacag gcaagaaaaa gaaaatattg gtaaagtatg agtacgatct
     5701 gggagcctgt atgttctgtc aactttgtgt gaacgcttgt ccacatgatg ccattcggtt
     5761 cgatacagaa ttcgagaatg ctgtgttcga ccgcagcaaa ctagttctca ctctgaacaa
     5821 aaaataaaaa acaaacgata ttatgacact acaactaatt gtattcattg tactggcgtt
     5881 gtttatcgct atctgttcgg tattggcagt cacgacctca cgtatcttgc gtgcagcaac
     5941 ttatctgctg ttcgttttat ttggtacagc aggtatttac ttccagctca actactcatt
     6001 cttgggagct gtacaattac tgatttacgc cggtggtata acagtgcttt atgtatttag
     6061 tatcttattg acctcttcac aaggagacaa agcagagaga ttgaaaaatg ggaagatggt
     6121 ggccggagct atttctacga tagcaggact ggctatctgt ctgttcgtca tgctgaaaaa
     6181 cgaattcttg ccctctcatt ttgtgcatgg tgaactggat gtacgcacta tcggtcatgc
     6241 actgatgggc atggaaaaat atcaatatat tcttcctttc gaagtaatca gcgtgttatt
     6301 actcgcttgc atcgtaggag gaatcctaat cgctagaaaa agataaaatt tatggtacac
     6361 atggaatatt atctggtggt ttccaccttt atgatgtttg cgggaatcta tggtttcttc
     6421 acccgccgca atttattggc catgctcatc agtgtagaac tgatactgaa ttcggtagac
     6481 atcaacttcg ccgtattcaa ccgatacctc tttcccgaag aactggaagg cttttttttc
     6541 gccttgttcg ctatcggcgt gagtgcggct gaaacagcag tagctattgc tatcattatc
     6601 aatatctacc gcaatgtacg caatatccaa gtgaagaact taaatgaaat gaaaaactaa
     6661 ttatggaaca tacaatacta atccttatcc tacctttcct cagtttcctg atactggggc
     6721 tggcaggtat gcgtatgaag aacgggctgg caggggccat cggcaccgtt tcactggcag
     6781 gggtggcgtt gctttcctac ctcactgcct tcaattattt tgcaggaggc cgtacggcag
     6841 aaggcgtcta tcctactctc acaccttata acttcgaatg gttacctttc acaacgaact
     6901 tgcatattga catgggaatt atgcttgacc ctatttccgt tatgatgcta gtcgttattt
     6961 ccaccgtcag tctgatggta catatctatt cattcggata tatgaaaggt gaaaaaggct
     7021 ttcaacgtta ctacgcattt cttagcctgt ttaccatgtc catgttggga ctcgtagtag
     7081 caaccaatat tttccagatg tatgtctttt gggaactggt aggtgtttct tcttatttac
     7141 ttatcggctt ttattacacc aagaaagaag cgattgccgc cagtaaaaaa gcatttattg
     7201 ttacccgttt tgctgattta ggctttctga tcggtatctt gatttacggc tattatgccg
     7261 aaacattctc gttcacaccc caacttcagg tacttgcagt tgccggaagt atgataccac
     7321 tggccttggg gctaatgttt atcggtggtg ccggtaaaag tgcaatgttt ccattgcaca
     7381 tctggttacc agatgctatg gaaggcccta ctcctgtcag tgcattaatc catgctgcta
     7441 ccatggtggt agccggtgta tatctggtag cccgtatgtt cccgttgttt ataggatatg
     7501 cgcccgaagt actgcactgg atagcttata tcggtgcgtt cactgcattc tacgccgcta
     7561 gtgtggcgtg tgcacaaagc gatatcaaac gtgtgctcgc cttctccact atatctcaga
     7621 ttggatttat gattgtcgca ttaggcgttt gtacttccat gaatcctcat gaaggaggac
     7681 taggctacat ggcatccatg ttccacctgt tcacacatgc catgttcaag gcattgttgt
     7741 tcttaggagc cggatgtatc attcatgccg tacacagtaa tgagatgagc gccatggggg
     7801 gacttcataa atacatgccc gtcactcact ggacattcct gattgcttgt ttggctatct
     7861 caggtatctg gccattctca ggttttttct ctaaagacga aattctgacc gcctgcttcc
     7921 aattcagtcc tgttatagga tggataatga caggcattgc cgccatgact gcattttata
     7981 tgttccgcct ttattattgt attttctgga atggagaatg gaaaggacac tcccacgaat
     8041 ccggactagg tgcacatact ccgcatgagg ctccacttac catgacattc ccgctgatgt
     8101 ttttagccgc tatcacctgt gttgccggat tcataccttt cggcaatctg atcagtagta
     8161 acggagaagc ctataccatt catctggata tgcagatagc tgctacaagt atcattattg
     8221 ctatagcatc catcgcttta gctacatgga tgtatgcagg taagaaacaa cccgtagcca
     8281 actatctggc acacacattc ccacgtttgc acacagccgc ttaccatcgt ttctatatgg
     8341 atgagatatg gttattcgta accaagaaaa tcatcttccg gtgcattagt actccgatag
     8401 cttggtggga ccggcacgtt atcgatcaat tctttaactt cactgcgtgg agtactcatg
     8461 ctaccgccga tgaaatacgt gacatgcaaa gtggaaacgt acagcaatac agtatttggt
     8521 tccttgcagg tgcattgata ttgacgctga tactattaat ttaatgaata ataaaaaatc
     8581 cgccgcatgg ccatttttta atttttaatt taaaaagatg aacatactaa gttttttcat
     8641 tatagttccc ttgttgatgc tcgcgagcct ttgggcttcg cgcagcatca atcaagttcg
     8701 cggagtgatg gttgtcggat cttccatttt attggcatta tccgtttacc tcaccattga
     8761 ttatatcgaa ctacgccaag ccggtgctac aggagagatg ctgttcacag ccagcacagt
     8821 ttggtatgca ccgctccata tatgctactc agtaggagta gacggtatat cagtagcaat
     8881 gttgctactt agttccatta ttgtattcac cggtactttc gcatcgtgga agttacaacc
     8941 attgacaaaa gaatatttca tgtggttcac tctattgagt gtaggggtat tcggattctt
     9001 cgtttcaaca gacctgttca ccatgttcat gttttatgaa gtagccctga ttccaatgta
     9061 tctgctcatc ggtgtgtggg gaagcggacg taaagaatac gccgccatga aacttacatt
     9121 aatgttaatg ggtggttctg catttctact gatcggaatt ctcggtattt tctatggtgc
     9181 aggtggtgaa acaatgaatt tgctggaaat cgccaaacta catattcctc atgaaatgca
     9241 acgcatcttc ttcccgctta tcttcttggg gttcggagtc ttaggagctt tgttcccttt
     9301 ccatacatgg agtcccgatg gtcacgcttc cgcaccgact gctgtttcta tgcttcacgc
     9361 tggggtattg atgaaactag gaggttacgg atgtttccgt gttgctatgt acctgatgcc
     9421 tgaaggtgcg gccatgtggg gagatgtatt cctgatattg accactattt ctgtagttta
     9481 cggtgcattc agtgctgtgg tacaaaccga cttaaaatat atcaatgcct attcatccgt
     9541 atcccactgc ggattggtac tctttgccct gctgatgatg acacgcacca gttgtacggg
     9601 tgctattctc caaatgttga gtcacggatt aatgaccgct ttgttcttcg cccttattgg
     9661 tatgatatac ggacgtaccc acacccgtga tgtccgatta atgggaggtt tgatgaagat
     9721 tatgcctttc ctggctgtag gttatgttat tgccggtctt gctaatctgg gacttccagg
     9781 actaagtggt tttgttgctg aaatgacggt ctttgtaggt tctttccaaa atgatgatac
     9841 attccatcgc gtatgtaccc tagtggcaac aacaagtatc gtcattaccg cagtttatat
     9901 cctgcgtgta gtaggtaaaa tcctttacgg caaagttttg aatcccgaac atctgaaact
     9961 cacagacgca acttgggatg aaagagtagc cgttatctgc ctcatcgcct gtgtagcagg
    10021 tttaggattg gctccattct ggataagcga tctgatcagt aacagtgtag aaccaatcat
    10081 aagtcaatta ttaaattaaa atttgagaat taaaaattaa aaaatagcaa tgatggacat
    10141 aactgcaata ctccatatgc atgccgaact gagtctgaca gccgttttta ttctgatgtt
    10201 tctgttagat ttatttttac cggctccaca acgtcactgg ttacgcccca tggcatgtat
    10261 cctgctgacc attcaactct tagcaaacct atggccggaa gaggtgactt tattcggcgg
    10321 catgtaccat tcaaccccta tggcgtctgt tctgaaaagc atcctgacca taggtaccat
    10381 actggttttt ctacaagcag acccttggct aaaacgtgaa gacacccgcc ataaacaagg
    10441 cgaattctac atccttaccc tcagtacctt gctgggtatg tatttcatgg taagtgcagg
    10501 gcacttcctg ctattcttcc ttggattgga attggcaacc attcctatgg cttgcctcgt
    10561 agctttcgat aaatataaag gacatagtgc cgaagccgga gccaaattca ttctttcagc
    10621 tttattctcc agcggtattt tcctctatgg tatttccatg atttatggga caacaggtac
    10681 tttatatttt gaagatatcc ctgccgaact gacaggaact ccattacaag ttcttgcact
    10741 agtattcttc ttctccggac tagcctttaa attaagcttg gtaccttttc atctgtggac
    10801 ggcagatacg tatcaaggtg caccgactac agtgagcgct tacctgtccg ttatttcaaa
    10861 aggcgcagct gcttttgctt taatgattat tttaatgaaa gtatttgggc caatgactga
    10921 acaatggagt gaaatactat gtattatcat tgtagccacc atcactatag ccaatctgtt
    10981 cgccatccgc caaaacaatc tgaaacgctt tatggccttc agtagtattt cacaagccgg
    11041 ctacataatg ttggctgtac tggctggaac tccgcagggc atggcatccc tagtatatta
    11101 tatagtagta tacattgctg ccaatctcgc cgtattcggt gtcatcaata ccattgaaca
    11161 acatacccac ggtaaaatag aacgcgaaga ttataacgga ctttataaga ccaaccccaa
    11221 actaactatg gtcatgacac ttgctctttt ctcattggca ggtatcccgc catttgccgg
    11281 attcttcagt aagttctttg tattcatggc agcattccat agtggatatt atcttattgt
    11341 atttatcgca ttggtcaata caatcatttc attgtattat tatttgttaa ttgtaaaagc
    11401 catgttcatc acacctaatg aagatcctat cggcaatttt cgtacagcaa ctccgatgcg
    11461 catcagtctg ttggtatgtg tagccggcat attcgcttta ggaattataa gtggggtata
    11521 tcaactatta agtgatacat caatactata aaattttagt tacaagaaga atcacaactg
    11581 aaatgattat tgtatttcta tgatcaatat tcttttactt tagaggcaga atcaatctgt
    11641 ttccaaagta aaagaatatc ttaaagtttc tattcaacaa atttatcatt atcttcgtag
    11701 caaattataa aaaataagca ctatgaagaa agtcctctat attacaatac tcgcctgctc
    11761 tactttatgg gtatcttgca cagagaaaaa taaacaatcc gtcagaacag attcctttat
    11821 agaaaagaat gtagcatttg cacgtgcaca aatcgggaat gaaatacgaa tcatagaaaa
    11881 atcagaaaaa tttacaaacc ccgttacact gaaaactgac agtaccattt attattgtga
    11941 ctacgccgac tggcgaagtg gttttttccc tgggtcagtg tggtatctat atgaactgag
    12001 tggcgacact actctcttat cattagctga taaatacact tcggccatag aagaagccaa
    12061 aaaactgact tggcaccatg atgtaggttt catgataaat tgtagtttcg gcaatggatg
    12121 gcgaacaact aaagtaccca gatacaaaga agtcatgata gaagctgccc gttcattggc
    12181 tactcgtttc cgtgaaaagc cgggaattat ccaatcatgg gatgtgaccc gaggctggca
    12241 atcggaacgc ggttgggaat gtccggtcat aatagacaat atgatgaatt tggagttact
    12301 atttgaagca actaaattat ctggtgattc cactttttat cacatagcag tgaaccatgc
    12361 agaccgcact ttgaaagagc atttccgtac aaacggaagt tgttatcatg taatagatta
    12421 tagtttggca gacggcatgg tacggcatag acaaacagcc caaggatatg cagacgaatc
    12481 gacttggagt cgtggacaag catgggctat ttatggttac actgtgtgtt accgggaaac
    12541 tcatgataaa aagtatctaa atcaggcatt gaagactttc caattcatga aaacacatcc
    12601 ccggcttccc aaagacttga ttccttattg ggatatggat gctcccaata ttcccaatga
    12661 accacgagac gcttcaagtg cttcttgtat agcttctgca ctttatgaaa ttagtacaat
    12721 ggatgtgcct gatgcaaaca gttataagat ctatgcagac agtattatgg cttctctagc
    12781 ctcaccaaac tatctggcat ctcttggaaa aaatggtaac tttttattaa tgcattcagt
    12841 gggcagtatt cctcatggca cagaaataga tgtaccttta aattatgcag actattattt
    12901 cctggaagca ctgaaacgaa agcgggacat tgaagaaggc acacgctaat tatacagaca
    12961 aacagataac catccgagta ccttcagtat aactcgagtc aacaaatatg ttaccagaca
    13021 aacgtttaat aattaaacgg cttaaatata accccaatcc gttaccttgt gcaaactcat
    13081 ccagtttgat aaaacacaga aatatttcct cccgtttttc gggaggaatg ccacagccgg
    13141 tatcggttac ttcaattcgt aacttacttt gtgccttatc caacctcatc ttaagagtta
    13201 tagatccaga atctgtaaat ttattagcat tatccaacag gttctctatc actaacgaca
    13261 aatacaattc attggtggaa acaaaaattt ccccttctgg taattccaaa tgataaatta
    13321 ttcccaccct gctccatcgt tctactttat ccatttcttg tctgcagata tgagttatct
    13381 ggtttgttca caaagaagag gcgcatcaga tgaatctaaa ttagccacta ccagcaagtg
    13441 atctatcaac gaagtgagaa tttccgcatt agcagtaata atacctgaaa agccaacaat
    13501 agcgtttaat ggagtccgta tttcatgaca catagaatta atgaatgctg ttttcatttt
    13561 ctcactttcc ccagcttttt gattcagttc acctaaaact ttttccatct gtctttcttc
    13621 aaatcatagt acaagtaaaa acaaatactc atcaccaata caagtaccat aaaaagtgta
    13681 attactaaaa tacgcctgtt cttagtttcc aaacggtaat tctcatggtt caattgatct
    13741 acttcatact ttacctgtag ttcactaagt tgttttttca gattggaaga tttaatggaa
    13801 tcctgcactt gtatatagag tttatgatac ttaaaagcat ttttattatc ttccatagcc
    13861 tcataaattt gtgaattgat atccaataat cccgggacat tagactgact tgtcatccaa
    13921 gcatatttta tcaagctgtc attagttatc aatgcattat ggaaactatg cttatataag
    13981 taataattat tcatgccaaa aaacaattat acttatcaat agactccgta acccaagcac
    14041 tcatcttgat catcagatta taatacttct ctaatttatc atcggataat ttatccgcac
    14101 gcatcaacaa agaagtataa cattggagat atcgtatatt aatattatag aaaggacgtt
    14161 gacgagcata gtacaactca taatattttc tatattgctg aagctatttt tcaacatatt
    14221 caatatatag atctccttta tctataaagt tcaaggtcga aagaaaattc catacagtac
    14281 aaatacgaaa cttgaatcct tcctcatatg gtaactgaca agccagctta taagcagttt
    14341 ccaaataggg atcagcctct tcatatttac cttcactaca caaagcatag cctgtaataa
    14401 aagtctgttc catctgtatg taaatatcat tcccacctat attttcttta cccataaaag
    14461 ccaattcctc tgttatagca gtttcaacct cattattcct gactctgcct gcaaacaatc
    14521 tcattcgtaa aaagaataaa tatggatgag attcttccag tgtcccaaca tcctttaaaa
    14581 gagacatata ataccaaaca gaatcggcat gataaacttt aatatacgag aaaaccaaat
    14641 cagaaagagt ctcaaacata tgagtcttat catttactgc ttttgcggtg aaatacattt
    14701 tattaagata atccacttct tcaggtttct caaaataaaa atcagccaaa cctctgtaaa
    14761 tctcaatttg tagagaaaac tctacaggac ttcctataat attcagaaga ctatctttgg
    14821 tagtagaaat actacttcct ataacaacaa aaatccccaa acagatatca gtatataaca
    14881 agtgatatat ttcataatat cagattatta aggtacgaat atacaaataa tatagcaatg
    14941 tagcagcaat tattctttca ttattagaat ttacacaata atgggcaatt aatccactta
    15001 ttttttaatt atatgcttta atattgcatc gtggatattt tctggcaact atgaaattat
    15061 taattattaa acatcaaata tatggtaaaa aagttagtta gtgtattttg tatatgtgca
    15121 tattttggac ttgctcatgc acaaatacca caagagattt g
//
