LOCUS       c00016_gnlPro..        23317 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNAIKFLL_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:27:03
            Original ID  :: gnl|Prokka|BNAIKFLL_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 11763
            Orig. end    :: 35080
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23317
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[21763:33492]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..21729
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23317
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23317
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_AA_metabolism"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG,
                     Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             497..2923
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MNTPISWIKAYVPDLDCTVQEYVDKMTLSGSHVENAVYLDKNLEK
                     IVVGRIEKIEKHPDADKLVICQVNVGDEEVQIVTGASNVFKGAMVPVVLDGGRVAGGHD
                     GSPNPENGIKIKKGKLRGVPSYGMMCSIEELGSTRDMYPEAPEDGIYIFDESKDVKPGD
                     DAVAALGLRDAVVEFEITSNRVDCFSMIGMAREAAATFEKPFYAPEVKEVGNNEKAEDY
                     ISVEVEATDLCPRYTARIVKNIKLAPSPEWMQRRLAAMGIRPINNIVDITNYVMEEYGQ
                     PMHAYDLNKIRGHKIVVKRANDGDVYTTLDGQERKLDKDVLMINDAEGPVGIAGIMGGE
                     NSMVTDDIQTMLFEAATFDGTNIRLSSKRIGLRTDASGKFEKGLDPENALEAINRACQL
                     VEELGAGEVVGGVVDVYPNPVEDVKIPFEPAKYNKLLGTNVSEEKMMEYFDRLEIGYDK
                     ETNMLLIPSFRQDLRCSADIAEEVARFFGYDNIPTTLPHGEATAGKKSFAARVEDVVMN
                     IAEQNGFCGGMCYSFESPKVFDKLLLADNDPLRQAIVIANPLGEDYSIMRTIELNGILT
                     SLAGNYNHRNKNVRLYEIGNVYLPKALPLTELPDERKRLTLGMYGECDFFMLKGVLEEM
                     FLKLGLDGKVDFEPSQEKPFLHPGRQALIYVGGAYAGFIGQVHPEVCENYDMKCEAYVA
                     GIDLPTVTEKATFDRRYEGVAKYPAVNRDISLVMKKDVFVGSLEKVMKEKGGKLLESIQ
                     LFDVYEGSQIEEGYKSVAFSLVFRSPERSLEAAEINKIVDKILKELEKMGVELRA"
     CDS             2920..3948
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MMKTSDFNFDLPQELIAQDPLEDRSSSRLMVLNKESGEIAHRIFH
                     DITEYLHPGDCLVINDTKVIPARLIGTKEDTGAHIEILLLKRKENDVWETLVKPGKKCR
                     PGARVVFGNGELKAEIVDVLEDGNRLVHFEYEGIFEEVLDRLGQMPLPPYITHKLQDKN
                     RYQTVYAKYEGSAAAPTAGLHFTKELLKQIEDMGVNIARVTLHVGLGTFRPVKVENVLE
                     HHMHSEYYNVTETAAKMINDTKKNGGRIIAVGTTSTRTLESVADENGIIHPGCGNTEIF
                     IYPGYKFKAIDCLITNFHLPESTLLMLVSALAGKEHIMAAYKEAVKERYRFFSFGDAMF
                     IQ"
     CDS             complement(4448..5413)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_17"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.7e-08,
                     bitscore: 24.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNFFIIMDEIQGNNIARNFSSEYFNYTINFIISKEFPALTDFPD
                     FSLILCDLDKNIELAKKHNLPVIAFSHKNNRQESLMGTPWLILDTDGLSPFFLNEVYCR
                     HYKKPLTITTTNRCIIRELTTRQLPELLQLQEENKNNPSGCFFPQNCTTYAEAEEFLQN
                     YIKNQYAFYGYGIYGIFNKENETFLGIAGFSPFENVITSDTLNSKEKNFKISENLSEKI
                     PGKKSKNISEHSSEKTSEKYPENDFNEYSAEIGYSVLKKWQQQGIASEILPPLIHFGKE
                     YLGFTKIVTRIEKNNIASIRLAKKNNLKILICQATEQTNS"
     CDS             5507..6982
                     /locus_tag="ctg16_18"
                     /transl_table=11
                     /translation="MRKEENTEKDELYGKLQVHFIENVEAEESSEEKESDSGNLSDETA
                     RKSVSAEKENRAKKPVQKDIEEASAKSKGKKSETQSDSSKTDSEDDVKEQKGSRKRRHS
                     KVNKQEAEAVEESFYKVTGEAEEHKSHPVRNAILGLLVLILVASAVVSYPIGKEYFQEK
                     SVAGKDIEITIEKGSTSRDVSAILKKKGIIRYEAAFLLKLYFSDYKGKLRYGTFDLNNG
                     MSLGKVIKELATQDGQKENKFTIPEGYTIEMTASKLEKEGIMSAQEFLTAVTNAAATSK
                     YKDVLPKKKKVFYQLQGYIYPDTYYLAKDITGDQLVAKILDEFDKKFDATRQEKAKKLG
                     MTVEEVLIRASLLQKETELPEEYPIIAGVIQNRLDKKMKLQFDSTAVYAITKGQYGIAR
                     VMYKDLKVDSPYNTYKHKGLPVGPICSPSLEAIDGVLNPQKNDYLYFQMDTVKNDGSNI
                     FSKTYEEHKAASATTEAAAETTTTAAKQKTTKK"
     CDS             complement(7170..8555)
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="MVKLIETVYNFLWGDLLTAPLPGGGTLPLSLLVILLIPTGVYFTI
                     RTKFLPIRLFKDMVGALFEKKDEEQSALSVIQTLIVSTATRVGMGNLVGVVAAISAGGA
                     GAVFWMWVTALIGSSTAFIEATLSQIYKEKDPLYGGYRGGPAYYIHRYFEEKSGKKKRY
                     VLLSVLFAISGLICWCGISQVVSNSVASAFKNAFHIPPIYTTVILVILAAIIVLRKNAT
                     VKVLDIIVPIMAGFYLLITLFIIITNITQLPGVFERIFSEAFGFRQVAAGGFGAVLMNG
                     IKRGLFSNEAGSGSAPCAAAAAVADNPVKVGLTQALGVFIDTLMICSCTAMIMLLTPTK
                     LTEGLVGMDLLQKAMEYHLGSFGVIFIAVTLWLFSFSTFIGILFYARSNVAYLFGDNWF
                     SQTAYKVLALAMLFVGGLAAYTIVWDLGDVGIGLMTIFNIIMLYPLSKKALNALKEYEK
                     KKF"
     CDS             8907..9350
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MRVITMIVIVSILLVISIIDFKIKIIPNQLNVLLFISGIWSGFVF
                     QEVTFLSRFLGVFSVSIPMFILAILCSGGLGGGDVKLMAASGVLLGIKWNIFAACAGLL
                     LGGLYGFFLLITKRAKRKDCFALGPFLCIGIAVVFFRYIFMKV"
     CDS             10001..13558
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EKR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_21"
                     /sec_met_domain="PFOR_II (E-value: 5.9e-17, bitscore: 52.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.1e-77, bitscore: 250.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3e-35, bitscore: 112.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-12, bitscore:
                     37.8, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-10, bitscore: 32.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00051, bitscore: 11.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4e-19, bitscore: 59.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRAKQSMDGNTAAAHVAYAYTDVAAIYPITPSSPMADSVDQWAA
                     AGQENIFGNQVVVSEMQSEAGAAGTVHGSLAAGAITTTFTASQGLLLMIPNMYKIAAEQ
                     LPCVFDVSARTVATQSLNIFGDHSDVYACRQTGFAMLAETNPQEVMDLSPVAHLAAIEG
                     KVPFINFFDGFRTSHEIQKIEKWDYADLKEMCNMDAVKAFREHALNPEHPAMRGSHENG
                     DVFFQHREACNSVYEALPAVVKKYMGKINEKLGTNYDLFNYYGAEDAERVIIAMGSICD
                     VAEEVIDYLTAKGEKVGLIKVRLYRPWVSSALLDVIPKTAKKIAVLDRTKEPGALGDPL
                     YLDVATTLREAGLNDIVLTAGRYGLGSKDTPPSSVFAIYKELEKDAPKSRFTIGIVDDV
                     TNLSLPEVKPAPITSAPGTVECKFWGLGGDGTVGANKNSTKIIGDHTDKYIQAYFQYDS
                     KKTGGITISHLRFGDNPIRSPYYINQADFVACHNPSYVVKGYKMVQDVKPGGIFMINCQ
                     WSDEELDHHMPAAAKKYIADNNIQLYTINAIDKAIEIGMGKRTNTILQSAFFKLANIMP
                     IDEAVEFMKAAAKKSYSKKGDAVVEMNYKAIDAGVDAVHKVEIPASWSNPAADAPAKEL
                     TGRPETVKMVKEMMEPIGIMDGDSLPVSTFVDNADGQFELGASAYEKRGTAVSVPEWNP
                     EACIQCNQCAFVCSHATIRPFLVSEDEIKAAPDNMKVADTKPKASEYKFTMSVSPLDCM
                     GCGECITVCPAAAKGALKMVPQESQAAEQPVFDYLVATVGRKPGAPADTTVKGSQFNQP
                     LLEFSGSCAGCAETSYARLITQLFGEHMYISNATGCSSIWGGPAATAPYTVNKDSKQGP
                     AWANSLFEDNAEHGFGMYLGQKTLRDQAIAKLEKMAASDKASDEFKAAFAKFMETKDNT
                     KENTPDAQALIAEVEKAAAAGCPDAAEVLEKKQYLAKKSVWIFGGDGWAYDIGFGGLDH
                     VLASGENVNVMVFDTEMYSNTGGQASKASNIGEVCQFAAAGKEISKKSLAEIAMSYGYV
                     YVAQIALGANPNQAVKCLAEAEAYNGPSLIIGYAPCELHGIAKGGMNHCQDEMKKAVKA
                     GYWNLFSFDPAKKAEGKNPFTLTSKEGDGSYQEFLNNESRYTRLIKPFPERAERLFNES
                     EKVAKARYEHLQRLVELYK"
     CDS             13761..15515
                     /locus_tag="ctg16_22"
                     /transl_table=11
                     /translation="MLYKEDFGEGKNIEFKREIPKRHEKLLKDVIAFSNSTGGKIFIGI
                     EDKTNEVIGIGEKNPFRLADDISNMIFDSCTPIIDPEITIQTLEGRTVVVVEVFPGRMR
                     PYYLKSFGKEQGSYIRINDTSRPADDRKLKELELEGQKISYDTLPEIDMEYSEREAKIL
                     CNAMEKVAYDVQTTCVTRAIQETSLDPKQNTEKTEIINKMTIEKLEDLGLLCRIGKDLQ
                     PTHAFRLMTKNKIRYAKIQCALFKGTERDIFIDKREFDGPLYVQLENAYQFVLKHINLG
                     AKIEGLHRKEAYELPVRTIRELITNAVVHRSYLDESCIQVCVYDDRIEVTSPGMLYGGL
                     DIQSAKSGKSKCRNTAIAEAFRYMGLIEAWGTGIPRMIKECREYGLREPVFEELGDGIR
                     ITIFRENEELEMRKRAENIQNAENKYQYMNNINSENLASVVKEQTVEYREQNHCFNTEK
                     SLFNALDSQGNEKKYCLNDEKTLFETTSQDKTHCFETSVLTAENKYMLYKKLKELQVNK
                     SIGSVTALNIKEIIESFSGEEVFGRKEIKQKLGYKDSKAGFLIQTMREFELIKDVKGRG
                     KGKYCFDI"
     CDS             complement(15619..16287)
                     /locus_tag="ctg16_23"
                     /transl_table=11
                     /translation="MIINKFYEKLYKELINKLESDYILIPNTPENRKAINNTLTTVPCT
                     VKSLEKDSKIFKALSNKKAKAKQLSIVPKISKTLSLIIIATLICMPFNTINTLPTPTYH
                     PTVQVSILDISDGSSHQKGKNKLSEIQEQYTNKNQEQRNPKNYKKKVATNTYNTYKKQN
                     KFHLTLSTKKATQLLSTFKKFFLKTKNTYDNLSDAYDVISTLFVLISTVKESIRSKKLK
                     "
     CDS             17194..21729
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_syn_central"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_24"
                     /sec_met_domain="GATase_2 (E-value: 2.1e-172, bitscore:
                     564.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_syn_central (E-value: 5e-112,
                     bitscore: 364.6, seeds: 570, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_synthase (E-value: 3.2e-153, bitscore:
                     500.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQDNMRQGLYDPSLEHDNCGIGAVVNIKGLKSHETVSNALKIVE
                     NLEHRAGKDAEGKTGDGVGILVQISHKFFEKTCSTLGFSIGKERDYGIGMFFMPQDELQ
                     RNRAKKMFEIIVEKEGLNFLGWREVPVQPGILGKKAADCMPCIMQGFVKRPFDVPRGLD
                     FDRRLYIVRRVFEQSNDSAYVVSLSSRTIVYKGMFLVGQLRLFYNDLQDKDYESAIALV
                     HSRFSTNTVPSWEKAHPYRYIVHNGEINTIRGNADKMLAREENMESDYLKDEMIKLTPV
                     VDPNGSDSARLDNTLEFLLMSGMPLPLAMMITIPEPWENNEGMSREKRDFYQYYATMME
                     PWDGPASILFTDGDIMGAVLDRNGLRPSRYYITDDDQLILSSEVGVLDFDTTHIVKKER
                     LHPGKMLLVDTVKGELIDDEILKDSYVKNQPYGEWLSDNLVFLKDLKIPNVAVEEYSYE
                     ESNRLMKAFGYSYEEVKDSVLPMALNGSEAIGAMGVDTPLAVLSKRHHPLFDYFKQLFA
                     QVTNPPIDAIREEIVTSTSIYVGGEGNVLEEKAENCHVLKIHNPILTNTDLLKIRYAKV
                     KNINVKDVPITYYKGTPLDKAINHLYVAVDQAHKNGANVVILTDRGVDENHVAIPSLLA
                     VSAVHHHLIETKKSTSVSIILESGEPREVHHFATLLGYGACAINPYLAQFSIKKLIQDG
                     LLKKDYYAAVNDYNNAVLHGIVKIASKMGISTLQSYQGSQIFEAVGISKKVIDEYFTNT
                     VSRVEGITIEDIAEDVDYHHSKAFDMLGLKNDLSLDSEGDHKYRSGKEEHLYNPLTIHT
                     LQTAAWTNNYELFKQYTSMINKETSPVSLRGLMDFNYPSKGVPIEEVESVDSIVKRFKT
                     GAMSYGSISKEAHETLAIAMNMIHGKSNTGEGGEDLERLTVGPDGLNKCSAIKQVASGR
                     FGVTSRYLVSAQEIQIKMAQGAKPGEGGHLPAGKVYPWIAKTRHSTPGVGLISPPPHHD
                     IYSIEDLAQLIYDLKNANRNARISVKLVSEAGVGTVAAGVAKAGAQVILISGHDGGTGA
                     APRNSSIHNAGLPWELGLAETHQTLIKNDLRNKVIIETDGKLMSGRDVAMAAALGAEEF
                     GFATGPLITMGCVMMRVCNLDTCPVGIATQNPELRKRFKGKPEYVVNYMKFVAQEMREY
                     MAKLGVRTVDELVGRTDLLKELPEAKEYHLDLSAILNNPYVDKKHPICYNKKNEYNFEL
                     EKTLDEKVLLTKLKTALDKKQKRSISIDVGNTDRSFGTIFGSEITKKYYNTLEDDTFTV
                     QCTGAGGQSFGAFIPNGLTLELVGDSNDYFGKGLSGGKLIVYPPKGIRFKAEENIIVGN
                     VALYGATSGQAYINGVAGERFCVRNSGATAVVEGVGDHGCEYMTGGKVLIIGKTGKNFA
                     AGMSGGVAYVLDEDNDLYLSLNKEMVSSEPVVSKYDVMEIKDMITAHVAYTNSEKGKEI
                     LNDFSKYLPKFKKIIPHDYKKMLKKISEMEGKGLSAEQAQIEAFYEIKRG"
     CDS             21742..23226
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_20"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:Dihydroprymidine dehydrogenase domain II, 4Fe-4S
                     cluster (Score: 69.9; E-value: 4.8e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_25"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.1e-26, bitscore:
                     82.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_20 (E-value: 1.9e-22, bitscore: 69.9,
                     seeds: 204, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFLEYERKESVGEAPLKRIKHFNEFHTPLSKKEQERQGAR
                     CMNCGVPFCQSGILIKGMVTGCPLNNLIPEWNDATYTGNWDEAYNRLRKTNPFPEFTGR
                     VCPHPCEVGCTCNLGGDPVNIKEKELSIIERAYESGLIKPEPPEVRTGKTVAIVGSGPS
                     GLCVAEYLNRRGHSVTVYERSDRVGGLLMYGIPNMKLEKTYIERKVKLMEKEGVVFKTG
                     VNVGVDVKAQDLKKQYDAVVLCCGASNPRDIKAPGRKSKGIYFAVDYLKAATKSLLDSN
                     FADKKYIDAKDKNVMVIGGGDTGNDCVGTSIRLGCKSLIQLEMMPKLPDERQPNNPWPE
                     WPRVCKTDYGQEEAIAVFGKDPRVYQTTVKEFIANEKGEVCKAKLVKLESKFDKKAGRN
                     IMAEVAGSEYEVPVDLVLIAAGFLGSQPYVTKAFGLDLTERTNVKTVEGHFKTNVDKVF
                     TAGDMHRGQSLVVWAIREGRDCAREVDKALMGYSNL"
ORIGIN
        1 accctaaggt attaagcgat tgcggaatcg acccagaagt atattcagga tttgcattcg
       61 gaatcggtct tgagagagtt acactcttaa aatatgagat tgacgatatg cgtctgttat
      121 atgagaacga tgccagattc cttaagcagt tctagagcgt gtttgaaaaa ccattcctgc
      181 aatctgcacg ccccaatttg cggtatattt tgccttcatt cagttgacgt agcccactac
      241 gccgccctca ttcaggtaaa atctcccaca aattgtaacg catatcttgc agaaagcatt
      301 tttcaaacac gctctagagc gtgcttgaaa agttatttca tcaatcagca gaaagaatta
      361 ttcaaatatt ttttagtaag accgagaaac ctaattcgat gaaatgtaaa aaggttaaca
      421 tgatgagaaa ctagaattat ctcggtaaga taaattcaaa atatatttaa gtttatagat
      481 ataaaaggag acaaaaatga atacaccaat ttcatggatt aaagcatatg ttccagattt
      541 ggattgtact gtacaggaat atgtagacaa gatgactctg tctggttccc acgtagagaa
      601 tgcagtatac cttgataaga atctggagaa aatcgttgtt ggacgaattg aaaaaatcga
      661 gaaacatcca gatgcagata aattagttat ctgtcaggta aatgtaggtg acgaggaagt
      721 acagattgta acaggcgcat ctaacgtatt taagggagct atggttcctg ttgttttaga
      781 tggcggacgt gttgcgggcg gacatgacgg aagcccaaat cctgaaaatg gaattaagat
      841 taaaaaaggt aaacttcgtg gagttccttc ttacggtatg atgtgttcta ttgaagaatt
      901 aggaagcact cgcgatatgt atccagaagc accagaagac ggtatttaca tttttgatga
      961 gagcaaagat gtaaaaccag gtgacgatgc agtagcagca ttaggacttc gtgatgcagt
     1021 cgtagaattt gaaattactt ctaatcgtgt agactgtttc agcatgattg gtatggcaag
     1081 agaagcagca gctacatttg aaaagccatt ctatgctcca gaagtaaaag aagttggaaa
     1141 taacgaaaaa gcagaagact atatctctgt agaagtagaa gctactgatt tatgtccaag
     1201 atacacagca agaatcgtaa agaatatcaa gctagctcca tcgccagaat ggatgcagag
     1261 aagacttgca gctatgggta tccgtccaat caacaatatc gtagatatca caaactacgt
     1321 tatggaagag tacggacagc caatgcatgc ttatgactta aataagatca gaggtcataa
     1381 aatcgttgta aaacgtgcga atgacggtga tgtatacaca acacttgacg gacaggaaag
     1441 aaagcttgat aaagatgtat taatgatcaa cgatgcggaa ggtcctgttg gtatcgctgg
     1501 tatcatgggt ggagaaaact ccatggttac agatgatatt cagacaatgc tttttgaggc
     1561 agctacattt gatggaacaa atatccgtct ttcttctaag agaatcggtc ttagaacaga
     1621 tgcttccggt aagtttgaaa aaggtcttga cccagagaac gcattagaag cgatcaaccg
     1681 tgcctgccag ttagtagaag agttaggtgc tggtgaagtt gttggtggtg ttgtagatgt
     1741 atatccaaat ccagtagaag acgtaaagat tcctttcgag ccagcaaaat acaataagct
     1801 tcttggaaca aatgtatctg aagaaaagat gatggaatac tttgaccgtc ttgaaatcgg
     1861 ttacgacaaa gaaacaaata tgttactcat cccatctttc cgtcaggatt taagatgttc
     1921 tgcagatatc gcagaagaag tagcaagatt ttttggatat gataacattc ctaccacact
     1981 tcctcacggc gaggcaactg caggtaagaa gtcatttgct gcaagagtag aagatgttgt
     2041 tatgaacatc gctgagcaga acggattctg cggcggaatg tgctattctt ttgaaagccc
     2101 taaagtattt gacaagttac ttcttgctga caacgaccca ttacgtcagg caatcgtaat
     2161 cgcaaaccca cttggagaag attacagtat catgagaacg atcgagttaa atggtatttt
     2221 aacttcttta gcaggtaact ataaccacag aaataaaaat gttcgtctct acgaaatcgg
     2281 taacgtatat cttccaaagg ctctgccatt aacagaactt ccagacgaaa gaaagcgttt
     2341 aactctcggt atgtacggcg agtgtgactt cttcatgtta aaaggtgttc ttgaggaaat
     2401 gttcttaaaa cttggtcttg acggcaaagt tgacttcgag ccatcccagg aaaaaccttt
     2461 cttacaccca ggaagacagg cactcattta tgtaggcgga gcttatgccg gatttatcgg
     2521 acaggtacat ccagaagtat gcgaaaacta cgacatgaag tgtgaagcat atgtagcagg
     2581 aatcgacctt ccaactgtta cagaaaaggc tactttcgac agaagatacg aaggcgtagc
     2641 aaaataccct gcagtaaaca gagacataag tcttgttatg aaaaaagatg ttttcgtagg
     2701 aagccttgaa aaagtaatga aagaaaaagg cggcaagtta ttagagagca tccagttatt
     2761 tgacgtttac gaaggttctc agattgaaga aggatataaa tccgttgcat tcagccttgt
     2821 attccgttcc ccagaacgaa gcttagaagc tgctgaaatc aacaagatcg tagataagat
     2881 tcttaaagaa cttgaaaaaa tgggagttga attaagagca tgatgaaaac aagtgatttt
     2941 aattttgatc ttccacagga actgattgcc caggacccgc tagaagaccg ttcctcatca
     3001 agattgatgg tgcttaacaa ggaaagcggt gagatagctc accgtatttt ccatgacatt
     3061 acagagtatc ttcatccggg agattgtctg gttatcaacg acacaaaagt tatcccagcc
     3121 cgtcttatcg gaacaaaaga agataccgga gcccacattg aaattctgtt attaaaaaga
     3181 aaagaaaatg atgtctggga aacacttgta aaaccgggca agaaatgccg tccaggtgca
     3241 agagtagtct ttggaaatgg agaactgaaa gctgaaatcg ttgatgtatt agaagatgga
     3301 aaccgtcttg tacattttga atatgaagga atctttgagg aagtattaga ccgcctcggt
     3361 cagatgcctc tgcctccata tatcacacat aaattacagg ataaaaaccg ttatcagacc
     3421 gtttacgcaa agtatgaagg atccgcagcc gcaccgacag ctggacttca ttttacaaaa
     3481 gaactgttaa aacagattga agatatgggc gtaaatatcg cccgcgtaac tctccatgtt
     3541 ggacttggaa ctttccgccc ggtaaaagtg gaaaatgtac tcgaacacca tatgcattct
     3601 gaatactata acgtaacaga aaccgcagcg aaaatgatta atgacactaa gaaaaatggt
     3661 ggcagaatca tcgcagtcgg aacaacaagt acaagaacac ttgaatccgt ggcagatgag
     3721 aatggaatca tccatccggg ctgtggtaac acagaaatct tcatctatcc gggttataaa
     3781 tttaaggcaa ttgactgtct gatcacaaac ttccatttgc cagaatctac tttgttaatg
     3841 cttgtatctg cactggcagg gaaagagcat attatggcag cgtataagga ggcagtgaag
     3901 gaaagatatc gcttcttctc ttttggagat gcgatgttca ttcaataaat tctgatttgc
     3961 gcagcaaagg agacgctttc aaagagagcc gataccctat atttgtgact ttagtcgctg
     4021 caggttgaat gttcgcttaa ccgcttgcat ccaacctttg ctccgaggcc acaaatatag
     4081 ggtatcggct ctctttggaa gctgtttgtt ggctgcccat gcaaattcag gatttatttt
     4141 gagaaagatt tgagggaggc ttcagacagt tgtgaccttt tgaggaattg aaatactgga
     4201 ggactgacac ttatcttatc attttaaatt atttgatatt ataactatct ttggaagatc
     4261 tctgggattt agccatttgc cttataactt ttttgctttc tttagcattt ttaccacaaa
     4321 tgaatttgtt ttttcaaaaa acaaattcat aaacacgctc tagttaatag aaaaaagtag
     4381 tgactataaa taactatacg attatggcac tggttcaagt gtcaatccta tagaatttca
     4441 tttaccttca ggagttcgtc tgctccgtag cctgacaaat cagaattttt aaattatttt
     4501 tttttgctaa ccgaatggag gcaatattat ttttctctat tctggtaaca attttcgtga
     4561 agcctaaata ttctttgccg aagtgaatca gaggaggaag aatttctgag gcgattcctt
     4621 gttgctgcca tttttttaga acagaataac cgatttcggc agaatattca ttaaaatcgt
     4681 tttcgggata tttttcggaa gttttttcgg aagagtgctc agaaatattt ttgctttttt
     4741 tcccgggaat tttctctgac aaattctcag aaattttaaa atttttttct tttgagttta
     4801 gggtgtctga agttattaca ttttcaaatg gtgaaaaacc ggcaattcct aaaaaagtct
     4861 cattttcttt gttgaagatt ccataaattc catatccata aaatgcatat tgatttttta
     4921 tataattttg aagaaattct tcggcttctg cgtatgtggt acagttttgt ggaaagaagc
     4981 agccggaagg gttgttttta ttttcttctt gcagttgcag aagttcaggg agttgcctgg
     5041 tggtgagttc tcggatgatg cagcggtttg tggtggttat agttagaggt tttttataat
     5101 gtctgcaata cacttcattt aagaaaaatg gactgagtcc atctgtatct aaaatcagcc
     5161 acggggtccc catcagggat tcttgtctgt tatttttgtg tgaaaatgcg atgacgggaa
     5221 ggttgtgttt ttttgcaagt tcgatgtttt tgtcaaggtc acataaaata agcgaaaaat
     5281 ctgggaaatc agtcaaggca ggaaactctt tagaaattat gaaatttatg gtatagttaa
     5341 aatattctga ggaaaaattc cgggcaatat tatttccctg gatttcgtcc ataataataa
     5401 aaaagttaaa cataacagaa tacctttcat tttatttttg tatattcttg tttatcatac
     5461 gaaagaaaag aaagattgta aaggatatct gttttggagg taaacaatgc gaaaggaaga
     5521 gaatacagaa aaagatgagc tgtatggcaa gctgcaagtt cattttatag agaatgtaga
     5581 ggctgaggaa tcttctgaag aaaaagaatc ggattccgga aatctttctg atgagacagc
     5641 tagaaagtct gtatcggcag aaaaggagaa tagagcaaag aagccagtac aaaaggatat
     5701 agaggaggca tcggccaaat caaaagggaa aaagtcagag actcaatcag atagttccaa
     5761 aactgatagc gaagatgatg taaaagaaca aaaaggcagc cgaaagcgca gacatagcaa
     5821 ggtaaataag caggaggcag aagctgttga ggaatctttt tataaggtga caggtgaggc
     5881 agaggaacat aagtctcacc ctgttagaaa tgcaatatta ggattattag tcctgattct
     5941 tgtggcaagt gcggttgtat cctacccaat aggaaaggaa tattttcagg aaaaatccgt
     6001 agcaggcaag gatattgaaa tcacgattga aaagggaagt acttcaagag atgtaagtgc
     6061 gattcttaag aaaaaaggta tcattcgata cgaggctgca tttttattga agctatattt
     6121 ctctgattat aaaggaaagc ttcgctatgg aacatttgat ttaaataatg gaatgagttt
     6181 gggtaaagtt atcaaagaac tggcaacgca ggacggtcaa aaagagaata aattcaccat
     6241 tccagaagga tacacgattg agatgacggc aagcaaactc gaaaaagaag gaattatgtc
     6301 cgcccaggaa ttccttactg cagtaacgaa tgcagctgcg acatcaaagt ataaagatgt
     6361 ccttccgaaa aagaaaaaag tattttatca gttacaggga tatatttatc cggataccta
     6421 ttacttagcg aaagatatta ccggtgatca gcttgtggca aagatactcg atgaatttga
     6481 taaaaagttc gatgcgacaa gacaggaaaa agcgaaaaag cttggtatga cagtggaaga
     6541 agttctgatt cgtgcatctc ttttacagaa agaaacagaa cttccggagg aatatccaat
     6601 tatcgcaggc gttattcaga atcgtcttga taaaaagatg aagttacagt tcgattccac
     6661 tgctgtatat gctattacaa aaggccagta tggaatcgca cgagtaatgt ataaagactt
     6721 aaaagtggat tctccatata acacatataa gcataaaggc ctgccagttg gaccaatatg
     6781 tagcccaagc ttagaagcga ttgatggagt gttgaatcca cagaaaaatg attatctgta
     6841 tttccagatg gatacagtga agaatgatgg ctccaatatt tttagcaaaa cttatgagga
     6901 gcataaggcg gcttctgcga ctacagaagc ggcagcagaa accacaacaa cggctgcaaa
     6961 acaaaaaaca acaaagaaat aacttctgct ttgtagcggc aaagcggacg ctcccaaaga
     7021 gaggctatac cccatatatg gggtatagcc tctctttgtg ggctgcctgt ggttgttgaa
     7081 gtaaaatcag gattcatatt ggaaaatttg aaaattttct ggaaagttgc gatttttttg
     7141 taatcgtctg tttatctaaa tcttatagtt tagaatttct tcttctcata ttctttcaga
     7201 gcattcagag cctttttcga caacggatac aacataatga tgttaaagat cgtcatcaat
     7261 ccaattccga catctcccaa atcccataca attgtatacg cagcaagtcc tccaacaaaa
     7321 agcattgcta aagcaagaac tttgtaagct gtttgtgaga accagttatc tccaaagagg
     7381 taagctacgt tggagcgtgc ataaaacaag attccgataa atgtagaaaa actgaataac
     7441 cataatgtta cggcaatgaa tattactccg aatgagccga ggtgatattc catagctttt
     7501 tgtaataaat ccattccaac gagtccttca gtgagctttg ttggagtaag gagcatgatc
     7561 atagcagtac aactgcagat cataagcgtg tcaataaaaa cgcctaacgc ctgtgttaat
     7621 ccgactttaa caggattatc tgcaacagcg gctgcggctg cgcaaggggc agaaccagaa
     7681 ccggcttcgt ttgaaaaaag gcctcgtttg attccattca taaggacggc accgaatccc
     7741 ccggcggcta cctgacggaa accaaaagct tcagaaaaga ttcgttcaaa tacaccaggg
     7801 agctgtgtga tatttgtgat gataataaac aatgtaatca gtaaataaaa tccagccatg
     7861 atgggaacga taatatccaa aacttttaca gttgcatttt ttcgaagtac gataattgcg
     7921 gcaagtatta caagaataac tgtagtgtaa atcggtggaa tgtgaaaagc atttttaaaa
     7981 gcagatgcta cggaattact tactacctga ctgatgccgc accagcatat aaggccggaa
     8041 atggcaaaga gtacagaaag aagtacataa cgttttttct tgccggattt ttcttcaaaa
     8101 tatcgatgaa tgtagtaagc aggtcctcct cgatatcctc catatagagg gtctttttct
     8161 ttataaatct gtgataaagt tgcttcgata aaagcggtgg aagaaccgat aagggcagta
     8221 acccacatcc agaaaacagc accagctccg ccagcggaaa ttgcggcaac tacaccgacc
     8281 agattgccca ttccaacacg agttgctgtg gaaacaatca aagtctggat gacggaaagt
     8341 gcgctttgtt cttcgtcttt tttttcgaaa agtgcgccaa ccatatcttt gaagagacgt
     8401 attggcagaa actttgtacg gattgtgaaa tacactccgg taggaattag taaaatgact
     8461 aaaagtgaaa gggggagtgt tccgccgccg ggtaagggtg cggtgagtaa atctccccat
     8521 aaaaaattgt atactgtttc gattaatttg accatattaa tttgtatcct cctgaaggta
     8581 gtatataatt tctttttaat tttgtaaata aatagttgac tctagaagaa aaatggcata
     8641 aaatggaaaa acaaacacat aaatggaata aaataactta aatagaaatt taatactttt
     8701 aaaagttcaa gagaaaataa tgaaagttat ttaaaaaatt atttttgagt caagttaaat
     8761 ctgtcagttg gaatggttta tagattaaac acatgttaat aactccattg cagggatttt
     8821 cataattata gtatttgggg ttacagggtc tgtaaaatag taaacttaat aaaaattctg
     8881 caattagcag gagccagggg gagtatatga gggtaattac aatgattgtt atagttagta
     8941 ttttactggt tatttctata attgatttta aaatcaagat aattccgaat cagttaaatg
     9001 tacttttgtt tatttcagga atctggagtg gttttgtttt ccaggaagtt acattcttaa
     9061 gtcgcttttt gggagtgttt tcggttagta ttccgatgtt catacttgca attttatgtt
     9121 caggcggact gggtggagga gatgttaagc taatggcggc aagtggagtg ttactaggga
     9181 taaagtggaa tatatttgct gcttgtgcgg gattactttt aggaggatta tatggatttt
     9241 ttctgctgat tacaaagcgt gcgaagcgaa aggattgctt tgcgttggga ccttttttgt
     9301 gtatagggat tgctgttgtg ttttttagat atatttttat gaaagtgtga gggagctgat
     9361 atggaattac cgtggattcc cacttaattt tcttttcatc acttctgagt aaaaagtcgt
     9421 ttttcgtgaa ttgtctcatt gacattttgt caaataatat gcctgttttc ctatagagtt
     9481 gtgttggctt cattcagttg acgtagccgc ccgttacgct gccttcattc aggcaaaatc
     9541 tcccgcaaat tgtgacacac atcttgcaga aagcattttt caaacacatt ctagtcgatt
     9601 aaattatgta aaattacgaa attgttattt ttaaaagatg gagataaatg gtgaaaacaa
     9661 agaggaatct cataaaataa ttaaaaaaat gaagaaaaaa tattagaatt ttaatcctga
     9721 ataatcctaa aattacaaca aaaaattatt gagaaaaaat ctaaaataag ccatatgtat
     9781 attgtataca aaactgttgg ctttatagca attttaacct aaaattgttc tcggaaaaat
     9841 acgttgtcaa ggggaaaaat tggcataaaa aggctgtttc gggcaagatt ttgtatttta
     9901 gaaggaacag ttccgaataa gctttacatt acctcaaaaa aatgataata ttatgtcgaa
     9961 tttaaaataa accacaactt ttgacaagga ggaataatca atgcctagag caaaacagtc
    10021 tatggatgga aataccgcag cagctcacgt agcatatgcg tatacagatg ttgcagctat
    10081 ctatcctatt acaccatcta gtccaatggc tgattccgtt gaccagtggg cagcagcagg
    10141 acaggaaaat atttttggta accaggtagt tgttagtgag atgcagtctg aggcaggtgc
    10201 agcaggtact gttcacggtt ctcttgcagc tggtgctatc acaacaacat ttacagcatc
    10261 ccagggtctt cttcttatga tccctaacat gtataagatc gcagctgagc agcttccatg
    10321 tgtatttgat gtatctgcac gtacagttgc tacacagtct ctgaacattt tcggtgacca
    10381 cagtgacgta tatgcatgtc gtcagacagg atttgctatg ctggcagaaa ctaacccaca
    10441 ggaagttatg gacttaagcc ctgtagcaca tcttgctgca atcgaaggta aagttccatt
    10501 catcaacttc ttcgatggtt tccgtacatc tcatgagatc cagaagattg aaaaatggga
    10561 ttatgcagac ttaaaagaaa tgtgcaacat ggatgcagtt aaagctttcc gtgagcatgc
    10621 tcttaaccca gaacacccag ctatgcgtgg ttctcacgaa aacggtgatg ttttcttcca
    10681 gcacagagaa gcttgtaact ctgtttacga agctttacca gctgttgtta agaaatacat
    10741 gggcaaaatc aacgaaaaac tgggaactaa ctacgattta ttcaactact atggtgcaga
    10801 agatgcagaa cgcgtaatca tcgctatggg atctatctgt gacgtagcag aagaagtaat
    10861 tgattactta acagcaaaag gtgaaaaggt tggtttaatc aaagttcgtt tatatcgtcc
    10921 ttgggtatct tctgcattat tagatgttat tcctaagaca gctaagaaga tcgctgttct
    10981 tgaccgtaca aaagagcctg gagcattagg agatccttta tatcttgatg ttgctacaac
    11041 tcttagagaa gcaggtctta acgatatcgt tcttacagct ggacgttacg gattaggttc
    11101 taaagatact cctccttcat ctgtatttgc tatttataaa gaacttgaaa aagacgctcc
    11161 aaagagccgt ttcacaattg gtatcgtgga tgatgttaca aacttatctt taccagaagt
    11221 taaaccagct cctatcacat ctgctcctgg tacagtagag tgtaagttct ggggtcttgg
    11281 tggagacggt actgtaggtg ctaacaagaa ctctacaaag attatcggtg accacacaga
    11341 taaatacatt caggcatact tccagtatga ctccaagaag acaggtggta ttacaatttc
    11401 tcaccttcgt tttggtgaca atccaatcag aagcccatac tacattaacc aggctgactt
    11461 cgtagcatgt cacaacccat cttatgtagt taaaggttac aagatggttc aggatgttaa
    11521 accaggcgga atcttcatga ttaactgcca gtggtctgat gaagaattag atcatcatat
    11581 gcctgcagca gctaagaagt atattgctga caacaacatt cagttataca caatcaacgc
    11641 gattgataag gctatcgaga ttggtatggg taaacgtact aacacaatct tacagtccgc
    11701 attcttcaaa ttagcgaaca tcatgcctat cgacgaagca gtagaattca tgaaagcagc
    11761 agctaagaag tcctacagca agaagggtga cgctgttgta gagatgaact acaaagctat
    11821 cgacgctggt gtagatgctg ttcataaagt agagattcca gcttcctggt ctaacccagc
    11881 tgctgatgct cctgctaaag aacttacagg acgtccagag acagttaaga tggttaagga
    11941 aatgatggaa cctatcggaa tcatggatgg tgacagcctg ccagtatcta cattcgtaga
    12001 caacgctgac ggacagttcg aacttggtgc ttccgcatac gaaaaacgtg gtactgctgt
    12061 atctgttcca gaatggaatc cagaagcttg tatccagtgt aaccagtgtg cgtttgtatg
    12121 ttcccatgct acaattcgtc ctttcttagt aagcgaagac gaaattaagg cagctcctga
    12181 caacatgaaa gttgcagata caaagccaaa ggcaagcgaa tacaaattta caatgagcgt
    12241 atctccatta gactgtatgg gatgtggtga gtgtatcaca gtttgtcctg ctgcagctaa
    12301 gggcgcatta aagatggttc cacaggaaag ccaggcagca gaacagccag tattcgatta
    12361 cttagttgca actgttggaa gaaaaccagg tgctcctgca gatactacag ttaagggatc
    12421 tcagttcaac cagccattac ttgagttctc cggatcttgt gcaggatgtg cagagacatc
    12481 ttacgctcgt ctgattactc agttattcgg agagcatatg tacatctcca acgcaacagg
    12541 atgttcatcc atctggggtg gtcctgcagc aacagctcca tatacagtaa acaaagattc
    12601 caaacaggga ccagcttggg caaactcctt attcgaggat aacgcagagc acggctttgg
    12661 tatgtatctt ggacagaaga ctttacgtga tcaggctatc gctaaattag agaagatggc
    12721 agcatccgat aaagcatccg atgaatttaa agcagcattt gctaagttca tggaaacaaa
    12781 agacaataca aaagaaaata cacctgatgc tcaggcatta atcgctgagg tagaaaaagc
    12841 agcagcagct ggatgcccag atgcagcaga agtattagag aagaaacagt atctcgctaa
    12901 gaagtccgta tggatcttcg gtggtgacgg atgggcatat gatatcggtt tcggtggatt
    12961 agaccatgta ttagcttccg gtgagaacgt aaacgttatg gtattcgata ctgagatgta
    13021 ctccaacaca ggtggacagg cttctaaagc ttctaacatc ggtgaggttt gtcagttcgc
    13081 agcagctggt aaagaaatca gcaagaagag ccttgcagag atcgctatga gctacggata
    13141 cgtatacgtt gcacagattg ctcttggtgc taaccctaac caggcagtta aatgtcttgc
    13201 agaagcagaa gcttacaacg gaccatccct gatcatcgga tacgctccat gtgaacttca
    13261 cggtattgct aagggtggta tgaaccactg tcaggatgag atgaagaaag ccgttaaggc
    13321 tggttactgg aacctcttct ccttcgaccc agctaagaaa gctgaaggaa agaatccatt
    13381 cacattaaca tctaaagaag gcgacggatc atatcaggaa ttcttaaata acgaatcccg
    13441 ttacactcgt ctgattaagc cattcccaga aagagctgaa agactcttca acgaatctga
    13501 gaaggttgct aaggctcgtt acgagcacct gcagagactc gttgagcttt ataaataata
    13561 aagcctgaac tggtcagtca gattagttat acaaaagata aaactacttt atgaaataca
    13621 aaagagaagc tatgtgtcag ctatgctgat gcatggcttc ttcttgtatg ttgaaaaaaa
    13681 gaagggaatt gtattataat aaatcataac aaattaatga ctgatagatg tactgacaat
    13741 ggttttgaag agggacagga atgctatata aagaagattt tggagaagga aaaaatatag
    13801 aatttaaaag agagataccg aaaagacatg agaagttatt aaaagatgtt attgcttttt
    13861 ccaattctac ggggggtaaa atttttattg gaattgagga taagacgaat gaagttattg
    13921 ggattggaga gaagaatcca tttagattag cagatgatat ttcaaatatg atatttgaca
    13981 gctgcactcc aataattgat ccggaaatta caatacagac attagaagga agaacagttg
    14041 ttgttgtaga agtttttcca ggacgtatgc gtccttatta tctcaagtca tttgggaagg
    14101 aacaaggttc ttatataaga ataaatgata caagtcgtcc tgctgatgat agaaagttaa
    14161 aggaactaga attagaaggt caaaagattt cttatgatac tttaccggaa atagacatgg
    14221 agtactcgga acgagaggcg aagatattat gtaatgcaat ggaaaaagtg gcatatgatg
    14281 tgcagacaac atgtgtaaca agagcaatac aggaaacgtc attagatccc aagcaaaata
    14341 cagaaaaaac tgaaattata aataaaatga caatcgagaa actagaagac ttagggttat
    14401 tgtgccgaat aggaaaagac cttcaaccca cccatgcgtt tagactaatg acgaagaata
    14461 aaatacggta tgccaaaatt caatgtgcgt tatttaaagg aacagaaaga gatattttta
    14521 tagataaaag agaatttgat ggaccattat atgtacagct ggaaaatgct tatcaatttg
    14581 tattaaagca tatcaatctt ggtgcaaaga tagaagggtt acatagaaaa gaagcgtatg
    14641 aactcccggt tcgaacaata agagaattga ttactaatgc agttgttcat agaagttatt
    14701 tggatgagtc ttgtatacag gtttgtgtct atgatgacag gatagaagta acatctcccg
    14761 gaatgcttta tgggggactg gatatacagt cagctaaatc aggtaaatca aagtgcagaa
    14821 atacagcgat tgctgaagca tttcgttata tgggacttat agaagcgtgg ggaacaggaa
    14881 tcccaagaat gataaaagaa tgcagagaat atgggttgag agagccagtg tttgaggaac
    14941 tgggagatgg tatacgaata actatattcc gggaaaatga agaattggag atgcgaaaac
    15001 gggcggagaa tatacagaac gctgaaaata aataccagta tatgaataat ataaatagtg
    15061 agaacttagc atctgtagta aaagaacaaa cagtggaata tagagagcaa aatcactgtt
    15121 tcaatacaga aaaatcactg tttaatgcgc tggattcaca aggaaatgaa aaaaaatact
    15181 gtttgaatga tgaaaaaaca ctgtttgaaa caacaagtca ggataaaacc cactgttttg
    15241 aaacgtctgt attgactgca gagaataaat atatgttata taaaaagctg aaagaactac
    15301 aagttaataa aagcataggt agcgtcactg cattaaatat aaaggagatt atcgaaagct
    15361 tttcaggaga agaagtcttt gggcgaaaag aaataaaaca aaaactggga tataaagaca
    15421 gtaaggcggg atttctgatt caaacaatgc gggaatttga gttgattaaa gatgtgaaag
    15481 gaaggggcaa gggaaagtat tgttttgata tttaaaactc tatcttggct ttcataagaa
    15541 aatttaaagc cgtacttctg tgaagaacgg ctttaatgta taattgaaaa tagtattgaa
    15601 taaaattata tagaaggact attttaattt ttttgagcgt atagattctt ttactgtgga
    15661 aatcaataca aataaagtac taattacatc ataagcatca gataaattat cgtatgtatt
    15721 ttttgtttta agaaaaaact ttttaaaagt tgataaaagt tgagttgctt tttttgtgga
    15781 taatgttaaa tggaatttat tttgtttctt atatgtatta tatgtatttg tagcaacttt
    15841 ctttttgtag tttttaggat tacgttgctc ttggtttttg tttgtgtatt gttcttgtat
    15901 ttcggataat ttatttttcc ctttttggtg agaagatcca tcagaaatat ctaaaatact
    15961 aacttgtaca gtagggtggt aggtaggcgt tgggagagtg ttaatggtat taaatggcat
    16021 acaaattaaa gtggctatta taataagaga taaagtttta gaaattttgg gtacaattga
    16081 aagctgctta gctttagctt ttttgttaga taaagcttta aaaatctttg aatctttttc
    16141 taaagatttt acagtgcaag ggactgtcgt tagagtatta ttaattgctt ttctattttc
    16201 tggcgtgtta gggattaaaa tataatcaga ttctagtttg ttgataagtt ccttgtagag
    16261 tttttcataa aatttgttaa taatcattgt gatttctcct ttcttttttc tataataata
    16321 aatgcgtatt tttttgcgaa atggcctctc ctttctgtat cgaatttcaa cattttttgt
    16381 tgattattat taatatgtat aattttttct ttttgtattg ctctgatttg ccatgtgtgt
    16441 aattaaaatc tcctttctta cattagtatg agagattagg gaaattttct ttttgaaaag
    16501 atagtttacg aaaaaagaat ccgattcttt ttttgctttt tcactacaaa tagtatgcta
    16561 gtttagacaa tggcataaaa ttgtagaatt caaccaatta cttacttaat tttcttaagt
    16621 tattttgtat acaatgttaa taaaatgcag gatttgtatt tgaaaattac atttataatt
    16681 gtatgaattg tctttaaatc tgaaaataac gatgaataaa gaggtgaaat cacaaacaaa
    16741 actgtacttt tataagaaca atataatcta aaaagaaata aaaaccaaat aaactaacta
    16801 caatatcccc taaaacaaga gtaataatca gaaaataata tattaaaaaa taaataatca
    16861 aattattaga caactcacct taatgtttat atttacaacc tatttaaaat gttgtaatat
    16921 gataacaaca aaaagaaatg caggaagtca ttacaactac ttctgaaaat gaatttgtta
    16981 ctttttaaat atgtaattat tcagagattt atagattttt attcagacta tagatactca
    17041 ttcaggatta tgaaatcata agattacaag agcatgagaa catgagaatc ataaggtttg
    17101 attaagagtt cctgataatt actaattaca aaaatataat ttacaactga tgaatattta
    17161 ctatttcata gtgatgcaag aaagggtgag accatgtatc aggacaatat gcgacagggt
    17221 ctatatgatc caagtctgga gcatgataac tgtggtattg gtgctgtagt aaacatcaag
    17281 ggtcttaaga gccatgagac agtatcgaat gccttgaaaa ttgttgaaaa tcttgaacat
    17341 agagccggca aggacgccga gggtaaaacg ggtgacggag taggtatctt agtgcagata
    17401 tcccataagt ttttcgaaaa aacctgtagt actctcggct tttctattgg caaggaacgt
    17461 gactacggta ttggtatgtt ctttatgcca caggatgagt tacagagaaa ccgtgctaag
    17521 aagatgtttg agattatcgt tgaaaaagaa ggcttaaatt tcttaggctg gagagaggtt
    17581 ccggttcagc cgggcatcct cggaaagaaa gcagcggact gtatgccatg cattatgcag
    17641 ggatttgtaa agagaccgtt tgatgttcca cgaggacttg acttcgatag aagactttat
    17701 attgtaagac gagtatttga gcagtctaac gattctgctt atgttgtttc tttaagcagc
    17761 agaacaatcg tatataaagg tatgttctta gttggacagt taagattatt ctataatgac
    17821 cttcaggata aggattatga atctgcaatc gcattagttc attcccgttt ctccacaaac
    17881 acagttccaa gctgggagaa agcacatcct tatcgttaca tcgttcataa tggtgagatt
    17941 aatactattc gtggtaatgc cgataagatg ttagcccgtg aggaaaacat ggaatctgat
    18001 tatctgaagg atgagatgat taagctgaca ccagttgtag atccaaacgg ttctgactct
    18061 gcaagattag ataatacatt agaattcctc ttaatgagtg gaatgccact tcctctggca
    18121 atgatgatca cgattccaga accttgggaa aataacgagg gcatgagcag agagaagaga
    18181 gacttctatc agtactacgc aacaatgatg gagccttggg atggtcctgc atctatcctc
    18241 tttacagatg gagatatcat gggagccgta cttgaccgta atggtcttag accttcccgt
    18301 tactatatta cagatgatga ccagttaatt ctttcttctg aggttggtgt gttagacttt
    18361 gacacaacac atatcgtaaa gaaagagaga cttcacccag gtaaaatgct tctcgtagat
    18421 actgtaaaag gtgaactgat tgacgatgaa atcttaaaag attcttatgt aaagaatcag
    18481 ccttacggtg aatggttatc cgataacctt gtattcttaa aagacttaaa gattccgaat
    18541 gttgcagtag aagaatacag ctatgaagag agcaaccgcc tgatgaaagc atttggttac
    18601 tcttatgaag aagtgaaaga ttctgtatta ccgatggcat taaacggaag tgaagcaatc
    18661 ggagcgatgg gggttgatac tccattagca gtactttcta agagacatca tccattattt
    18721 gattacttta aacagctttt tgcacaggta acaaaccctc ctattgatgc gattcgtgag
    18781 gaaatcgtta catctacttc catctatgtt ggcggagagg ggaatgtgtt agaagaaaag
    18841 gcagaaaact gccatgtatt aaagattcac aaccctattt taacaaatac agacttatta
    18901 aagattcgtt atgcaaaagt aaagaatatc aatgtaaaag atgtgccgat tacttattac
    18961 aaaggaacac cgcttgataa ggctatcaat catttatatg ttgctgttga ccaggcgcat
    19021 aaaaatggtg caaatgttgt tattttgaca gatagaggtg ttgatgagaa ccatgtggca
    19081 attccatctc tgttagcagt atctgctgta catcatcatc tcattgagac aaagaagagt
    19141 acttctgtaa gtattatctt agagagtggt gaaccaagag aagtacatca tttcgccaca
    19201 ctgttaggtt acggcgcatg tgctatcaac ccatatctgg cacagttcag tattaagaag
    19261 ctgattcagg atggtttatt aaagaaagat tactatgcag cagtaaatga ttacaataac
    19321 gcagtacttc acggtatcgt aaagatcgca tctaagatgg gtatttccac actgcagtcc
    19381 tatcagggtt ctcagatttt tgaggcagtt ggtatcagca agaaagtcat tgatgagtac
    19441 tttacaaaca cagtaagccg tgtagaaggt atcacaattg aagatatcgc agaagatgta
    19501 gattaccatc actccaaagc atttgatatg ttaggactga aaaatgatct tagtcttgac
    19561 agtgaaggtg atcacaaata tagaagtggt aaagaagaac atctttacaa tccactgacc
    19621 atccatacat tacagacagc agcatggaca aataattatg aactgtttaa acagtatact
    19681 tccatgatta ataaagaaac ttctccagta agtcttcgtg gattaatgga tttcaattat
    19741 ccatccaaag gagttcctat cgaagaagtt gaatctgtag attctatcgt gaaacgattt
    19801 aagacaggtg ctatgagtta tggttctatt tccaaggaag cacatgagac tctggcaatc
    19861 gcgatgaaca tgattcacgg taaatcaaac actggtgaag gtggagaaga tttagagcgt
    19921 ctgacagttg gtccagatgg actgaataaa tgctctgcaa tcaagcaggt agcttccggt
    19981 cgtttcggtg taacaagccg ttaccttgta agtgcacagg aaattcagat taagatggca
    20041 cagggagcaa aacctggtga aggtggacat ttaccagcag gaaaggtata tccttggatt
    20101 gcaaagacaa gacattcaac acctggtgta ggactaatct caccaccacc tcatcacgat
    20161 atttacagta ttgaagattt ggcacagtta atttatgatt tgaaaaatgc aaacagaaat
    20221 gcccgcattt ctgtaaaact ggtatctgaa gcaggtgtcg gaacggtcgc agccggtgta
    20281 gcaaaagctg gcgcacaagt aatccttatt tccggacatg acggtggtac aggtgcagca
    20341 cctcgtaatt cttctatcca taatgccgga cttccgtggg agcttggact tgctgagaca
    20401 caccagacat taattaaaaa tgaccttcgt aataaagtta tcatcgagac ggacggtaag
    20461 cttatgagcg gccgcgacgt agcaatggca gcagcacttg gagcagaaga atttggattt
    20521 gctactggtc cgctgatcac aatgggctgc gttatgatga gagtttgtaa cttagatact
    20581 tgtccagtag gtatcgcaac acagaatccg gaacttagaa aacgtttcaa aggtaaaccg
    20641 gaatacgttg taaactacat gaagttcgtt gcacaggaaa tgcgtgaata catggcaaaa
    20701 cttggtgtcc gcactgtaga tgaactggta ggacgtacag accttctgaa agaacttcca
    20761 gaagcaaaag agtaccactt agatttatct gctattttaa ataatccata tgtagataag
    20821 aagcatccaa tctgctacaa caagaagaat gaatacaact ttgaattaga aaagacatta
    20881 gatgaaaaag ttcttcttac taagttgaag acagcgcttg ataaaaagca gaagagaagc
    20941 atttctatcg atgttggaaa tacagaccgt tcctttggta caatctttgg ttctgaaatt
    21001 acaaagaaat attacaacac actggaagat gatacattta ctgtacagtg tacaggagcc
    21061 ggcggacaga gctttggagc atttattcca aatggtctta cattagagct tgtcggtgac
    21121 agtaatgatt acttcggaaa aggattatcc ggtggtaaat taatcgttta ccctccaaaa
    21181 ggaatccgct tcaaagccga ggaaaatatt atcgttggta acgtagcact ttacggtgca
    21241 acaagcggtc aggcttatat taatggtgtg gctggtgaac gtttctgtgt tcgtaactcc
    21301 ggtgcaacag ccgttgtaga aggtgtcggc gatcacggat gcgagtacat gactggtggt
    21361 aaagtcttaa ttatcggtaa gactggaaag aacttcgcag ccggaatgag cggcggtgtt
    21421 gcctacgttc ttgatgagga taacgactta tacttaagcc tcaacaagga aatggtttct
    21481 tccgaaccag ttgtttctaa atatgatgtt atggaaatta aggatatgat taccgcccat
    21541 gtggcatata caaactctga aaaaggtaaa gaaattttaa atgattttag caaatattta
    21601 ccaaagttta agaaaatcat tccacacgat tacaagaaaa tgctcaagaa gatttccgaa
    21661 atggaaggaa aaggtcttag cgcagagcag gcacagattg aagcatttta cgaaattaaa
    21721 agaggatagg aggagagcgc tatgggaaaa ccaactggat ttttagaata tgaacgaaaa
    21781 gaaagcgtgg gagaagcgcc gttaaagaga atcaaacatt ttaacgaatt tcacactccc
    21841 ctgtccaaaa aagaacagga gagacaggga gcaagatgta tgaactgtgg agttccattt
    21901 tgccagtccg gtattttgat taaaggaatg gttaccggat gcccgcttaa taatctgatt
    21961 cctgaatgga atgatgcaac ttacacaggt aactgggatg aagcttataa ccgtcttaga
    22021 aagacaaatc catttccaga atttacaggt cgtgtatgtc cacatccttg tgaagtcgga
    22081 tgtacctgta acttaggcgg ggatccggtt aacatcaaag aaaaagagtt aagtattata
    22141 gagcgagctt atgaaagtgg cctgatcaaa ccggaaccac cagaagtccg cacaggaaag
    22201 acagttgcta tcgtaggttc cggtccatct ggactctgcg tggcagaata cttaaaccgc
    22261 cgtggccatt ctgtaactgt ttacgagcgt tccgaccgtg ttggtggact gctcatgtac
    22321 ggaattccta acatgaagct tgaaaaaaca tatattgaga gaaaagtaaa gctcatggaa
    22381 aaagaaggcg ttgtattcaa gacaggcgta aacgttggtg tagacgtaaa agcacaggac
    22441 ttaaagaaac agtatgatgc tgttgtgctt tgctgtggag cctctaatcc aagagacatc
    22501 aaagcaccag gcagaaagag caaaggaatt tattttgcag tagattactt aaaggcagca
    22561 acaaagagcc ttttagattc taacttcgca gataaaaaat acattgatgc caaagataaa
    22621 aatgtcatgg ttatcggtgg cggtgacaca ggaaatgact gtgttggaac atccatccgt
    22681 ttaggatgta agagcctcat tcagttagaa atgatgccaa aacttccaga tgaacgtcag
    22741 ccaaataacc catggccaga atggcctaga gtctgcaaga cagactacgg tcaggaagaa
    22801 gctatcgctg tatttggcaa agacccacga gtatatcaga caaccgtaaa agaattcatt
    22861 gccaatgaaa aaggtgaagt ctgcaaggca aaactcgtaa agcttgaaag taaattcgac
    22921 aaaaaagccg gaagaaatat catggcagaa gtcgctggca gcgagtatga agtacctgtt
    22981 gatttggtat taatcgcagc aggattctta ggaagccagc catatgttac aaaagctttt
    23041 ggcttagatc ttacagaacg cacgaatgta aagacagtag aaggacattt caagacaaat
    23101 gtagataaag tctttactgc aggtgatatg catcgaggac agtcacttgt tgtatgggca
    23161 attcgcgaag gtcgggactg tgcaagagaa gttgataaag ccctgatggg atactcaaat
    23221 ctgtaacttc tggtttgccg caggcaaaga gacgctcgca gtaaataaaa gaacctatat
    23281 ttgtgacttt agtcgctgcg gtttgaatac tcgctta
//
