LOCUS       c00066_gnlPro..        14210 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNAIKFLL_66.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:27:03
            Original ID  :: gnl|Prokka|BNAIKFLL_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14210
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14210
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1953:10568]"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /neighbourhood="10000"
                     /product="pdu"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1954..10568
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /neighbourhood="10000"
                     /product="pdu"
                     /protocluster_number="1"
     cand_cluster    1..14210
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aldedh, BMC,
                     Cob_adeno_trans, EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like,
                     PTAC, PduV-EutP]) and Dehydratase_MU and Dehydratase_SU and
                     Dehydratase_LU)"
                     /kind="single"
                     /product="pdu"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14210
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="pdu"
                     /region_number="1"
                     /rules="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /tool="gutsmash"
     CDS             complement(48..926)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_1"
                     /sec_met_domain="Flavoprotein (E-value: 3.5e-16, bitscore:
                     49.4, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRKEFEDALMATIVEYISDQVILRYAQACKKATVLFSGALIGYK
                     DAVTSLNELKKDGWTLTAVLSKAAGEVITEERIRNDIGPDAIYVEGAPVNGRQIVDDSQ
                     FVIIPSLTINTAAKVANCISDNLLTNMISRAMATGKPIVAAIDGCCPDNKVREQLGFKV
                     TEAYKAKMRHNLEDMLAYGITLTTDYSLCSKVNEVFSAKVSLPALDNSKPAPKKDRIVS
                     TKMEPAVQSVSQPVKKVETPSSVKLDKKVIGRVDIAKNARFKTIVVRQDALVTGLAKDE
                     ALNRGITIVKE"
     CDS             complement(935..1753)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MreB_Mbl"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_2"
                     /sec_met_domain="MreB_Mbl (E-value: 1.7e-11, bitscore:
                     33.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDYNNVLVGFSELIKNEEFRPYEGDLRLGVDLGTANIVVSVVDS
                     NNTPIAGASYPSTVVRDGIVVDFMGASRAVRNMKAKLEDLMGVEFYEAATAIPPGIISG
                     NVKVISNVVESVGLDVVNVIDEPTAAASVLGITDGAVVDVGGGTTGISILKDGKVIFTA
                     DEPTGGTHMTLVLAGSLGCSFEEAERIKKDPKQEMLVFPVVKPVIEKMAAIVARFIEGY
                     DVDVIYVVGGACSFKKFESVFEKETGVKTIKPKEPLLVTPLGIAMNCNKQ"
     CDS             complement(1954..2751)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 70.6; E-value:
                     2.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_3"
                     /sec_met_domain="BMC (E-value: 6.7e-23, bitscore: 70.6,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSNNKCLGFIETFGLAACVAAADAAVKSANVKLLGYEYAKGGGMC
                     TVKVEGNVGACRAAIAAGKKAAEAVNGSLSGTKSTLLKARPADGMRELLVDNRETVGGE
                     IALAEGYRPKGDTKKPVLVKNWKPKTEPKAEVVTEEAPEPPVVEEPEEEEPTSEEPETE
                     EVKEEAPVEEPKAEEPAEETPVEETPVEEAPVEEPKAEEPAPEAPAEETPVEKAEAEEA
                     KSEETEPKKETDKKADAPKGKTSTGNRRSRSRRKKNTDNNDNK"
     CDS             complement(2795..3157)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_MU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_4"
                     /sec_met_domain="Dehydratase_MU (E-value: 8.7e-36,
                     bitscore: 112.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGSNTVIDNRPSVKVFYDCDHLSEADFVSVLLGIEEEGIPYDVQ
                     AEHCSSVLELAHNASLNSRLGVGVGISKEGVVLQHEKLDKAAPLFKIKLYQTELFRKIG
                     ANAARLVKKMPFKVLD"
     CDS             complement(3167..4981)
                     /locus_tag="ctg66_5"
                     /transl_table=11
                     /translation="VKLVAGVDIGNATTETAIARIDGKNVTFLSSGITGTTGIKGTKQN
                     IHGVFQSLKNALDEVGFEISDLDEVRINEAAPVIGDVAMETITETIITESTMIGHNPNT
                     PGGVGIGVGISQRIDRLDTVKDGGDVIVVIPAEVSFEAAAALINRYNKIFNITGAIVQR
                     DDGVLINNRLEKKIPIVDEVGMIDKVPLGMLCAVEVAPVGGVVEVLSNPYGIATLFKLS
                     PEDTKQVVPIARALIGNRSAVVIKTPEGDVKERRIPAGSIEIIGAKKKVIVGVEEGAEK
                     MMEAVNSVPVIEDIKGEPGTNAGGMLEKVRQVMSNLTNQHPKDIKIQDLLAVDTYNPQK
                     IKGGLANEFSLESAVGIAAMVKADRLQMKMIAEELTDRLKIPVYVGGVEADMAIKGALT
                     TPGTNVPLAIVDMGAGSTDASIKDRDGNVKLVHLAGAGNMVTLLIQSELGLEDFNTAED
                     IKKYSLAKVESLFHIRHEDGTVQFFEQPLDPNVFAKVVLVKEDGELVPLEGQDSMEKIK
                     MVRTNAKKKVFVTNAIRSLAKVSPTGNVRDIEFVVLVGGSALDFEVPTLVTDALSQYNI
                     VAGRGNIRGCEGPRNAVATGLAMSCADV"
     CDS             complement(5014..5508)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_SU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_6"
                     /sec_met_domain="Dehydratase_SU (E-value: 2.3e-60,
                     bitscore: 192.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDQELLVRQIMQEVMKNMQGSAAACECESKVTVEDYPLGEKKPEL
                     IKSASGKSLNDLTLQGVIDGKLDAKDFRITKETLELQAQVAESAGRGFFATNLRRAGEL
                     IPVPDARLLEIYNALRPYRSTKAELYAIGDELINEYGATVSGNFVKEAADIYEKRNRLK
                     K"
     CDS             complement(5524..6183)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_MU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_7"
                     /sec_met_domain="Dehydratase_MU (E-value: 1e-41, bitscore:
                     131.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDEKLLKSVIAEVLKEMNTADTSAASAVEGETYECPGMQITEI
                     GDAEKGTNPNEVVLGLAPAFGESQTTNIVGIPHADIVKEVMAGLEEEGVSCRIVKVYRT
                     SDVSFIAHDAAELSGSGIGIGIQSKGTTVIHQKDLPPLSNLELFPQCPLIDLETYRAIG
                     KNAAQYAKGESPNPVPVKNDQMARPKFQALSAVLHIKETEHADRDKAPKALKVVFK"
     CDS             complement(6207..7868)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_LU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_8"
                     /sec_met_domain="Dehydratase_LU (E-value: 0.0, bitscore:
                     1018.4, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRSKRFEYLDQRPVNQDGYAKEWPEVGFIAMNSPFDPTPSIKIVN
                     GEVVEMDGKTKDEFDMLDAFIARYAINLDFAEEAMATDSLEIARMLVDINVNRQECLKY
                     TTAVTPAKLVEIVGNLSVLEAMMGITKMRCRLKPANQCHVTNVKDNMVQIAADAAEAAV
                     RGFAEMETTVGIVRYAPFNAIAIMLGANVGRPGILTQCAVEEATELDLGMRGYTAYAET
                     VSVYGTEDVFMDGDDTPWSKAFLASCYASRGVKMRFTSGTGSEVQMGMAEGKSMLYLEA
                     RCLGVTRGAGVQGTQNGSVSCIGVPAAVPGGIRAVACENLIAAMLDLENASSNDQSFTH
                     SDLRRVARSIPQFIPGTDYICSGYSSTPNYDNMFAGSNWDADDYDDWCVIQRDLRVDAG
                     LLPAREEEVVAARNKAAKAIQALFRELGLPEITDEEVEAATYARGSQDMPDRDVVADLK
                     AATDMLDRGVTGIDFVKALYKGGFEDVAESIFNIQKAKVVGDYLHTASMLDDKFHVISA
                     VNSPNCYEGPMTGYQISPELWEKISDIRTAVDPAKL"
     CDS             complement(8050..8862)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 36.5; E-value:
                     1.2e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_9"
                     /sec_met_domain="BMC (E-value: 2.9e-12, bitscore: 36.5,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDEMMAKIMDEVMKKMGGTEAPAQSMACEAPQGINEDLCGLTEY
                     VGTAMGHTIGLVIANLDYSVHELLKIDPKYRSIGIIADRTGAGPQIFACDEAVKATNTE
                     VCLIECPRDTEGGAGHGCLVVFGAEDVSDARRAVEVALSFVGKHFGDVYGNSAGHLEFQ
                     YTARASYCLEKAFGAVVGKAFGITVGAPSGIGIVLADTASKTATIDPISIATPGNGGTS
                     FSNEVNFFFTGDSGAVRQAIIGAREVGKQLLKALEPNEPLESGTVPYI"
     CDS             complement(8906..9178)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 102.9; E-value:
                     2.3e-32)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_10"
                     /sec_met_domain="BMC (E-value: 5.6e-33, bitscore: 102.9,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKEALGMIETKGLVGAIEAADAMVKSANVTLVGYEKIGSGLVTV
                     MVRGDVGAVKASVDAGTVAADKVGTVVSSHVIPRPHTDVEKILPQ"
     CDS             complement(9414..10568)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     374; E-value: 2.1e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_11"
                     /sec_met_domain="Fe-ADH (E-value: 5.2e-115, bitscore:
                     374.0, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRFKLSTEVLFSEDAIDALLEEKDENAVLITDKFMVDSGMADMI
                     LKKLSNCKEVSVFSEVVPDPPMDLIERGIAFLQDKDCDIVVALGGGSSIDAAKAIVYMA
                     KKIEEKQNPDNQKKIKLIALPTTSGTGSEVTQFAVVTDSKTGVKIPLIDESLMPDIAIL
                     DPELVKSAPPFITADTGLDVITHALEAYVSETASDCSDCLAEKAAELAFEFLPRAYRNG
                     YDIKARDKMHRASCLAGMAFNLVNLGVNHGIAHALGAIFHIPHGRANALVLPYVIEFNA
                     DMAREGAKHSNDAAKKYQKMARIVGLPAPTPKVGVANLIAEIQRLLKYMDRPQCMSECG
                     VSVEEFNKHREEIVRRALADACTQANPRKVTAEDINKILDHIAK"
     CDS             complement(10555..11622)
                     /locus_tag="ctg66_12"
                     /transl_table=11
                     /translation="LYKILIVEDEELERTSMKIFLEENLLDVEIVGEAKSGFEAVEMID
                     SKDINLMLVDINIPGMDGMEVIKYARKKLPKAVIIITTAYDDFNIAHRAIKLKVDDFLL
                     KPIRKEVLLESVKSFASRLGEGRQTGKSNKLLSKFEMELKKCSYKASVDILREYIDQLY
                     LEEHDVNIISKRLQEVAKAVVRISEELGITDTNELVVQMEKLKIKYLLYNNKHDAYNEI
                     IKMVDILFDKMNIKGKLSEGGMKAVIDYIERNLKKGISLEDVANHVNISTYYLSKIFKK
                     EMGVNFITYVTDRKMDLAKEMLVNTDIPVLNIALDLAYNEANYFSKAFKKKTGLTPSEY
                     REKYRNRKEEENETV"
     CDS             complement(11638..12873)
                     /locus_tag="ctg66_13"
                     /transl_table=11
                     /translation="LTEKNNIYIEDVVDVKELQTLQDNWAKATDLAFVTVDCNGTPITK
                     QSNFTPFCKRLRELDAFREKCYYCDACGGRKARRIGKAYVYICHAGLIDFAIPIMIKGQ
                     YVGAFLAGQVTSTDFADLKKITTQSEDWKDNQELVELYSQVKEVSVEKIEAVAQIICDS
                     YNYSVEREYANKVNAELREKDYKLMKEEKLRIEMEKSLRDIELKALHYQINPHFLFNVL
                     NTIGRLAFFENAKMTEDVVYAFADMMRYILRKSRDPLSPLREELTHVQNYLKIQKIRLG
                     SRLQYSINISETYYSVKLPFLSLTTLVENSIKYAVENKASGGMVEVNGSEKDGDLCIDI
                     IDNGDGMSQSKIVSVLRGDAYKDNEKGSVGLYNINSRLIHYFGNEYALSIESENKPSLG
                     TKVTIKVPLVQE"
     CDS             complement(12923..13585)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_14"
                     /sec_met_domain="B12-binding (E-value: 3.5e-21, bitscore:
                     65.5, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATIDEIIDSLKRGQGKRVSDLVKMALEEGTDPQMILEDGFLAG
                     MEQVADKFRKEEVGVPEILSVTRALERGVSTLRHYSGGRAKKEIGTVIIGTVKGDLHDI
                     GKNLVKIMMESKNIRVIDLGVDVSPRRFLEEAVGSHAQIVCLSGIMPHSEEDMRAVVEE
                     FEMKGIRDQFYFMVGGYFLTERQAKAIGADCYTEDACNCAEKACRYLNKKDRRKKNH"
     CDS             complement(13793..14053)
                     /locus_tag="ctg66_15"
                     /transl_table=11
                     /translation="MLAYALAFKPCSEVTDIGSILSWGSVFWRDLVRIRRIQDFPEYQL
                     GVKGMKLGVQSYGRIWGFYGVTVGGEGAGVQVSSVFCKPKS"
ORIGIN
        1 gaaactactg taccaatcac tttacctaaa tacatgtctt cacctactta ctcttttaca
       61 atcgtaattc cgcgatttaa agcttcatct tttgcaagac cggtaactaa tgcatcctgt
      121 cttacaacga ttgtcttaaa tctcgcattc tttgctatat cgactctgcc gattactttt
      181 ttgtctaact ttacactgct cggtgtttcc acttttttga ctggctggct tactgactgt
      241 actgctggct ccatctttgt ggaaacaatt ctgtctttct tcggtgccgg cttactgtta
      301 tccagtgccg ggagagacac ctttgcagag aaaacttcat ttactttact acacagacta
      361 tagtctgtag tcaatgtgat tccgtatgcg agcatatctt caagattatg tcgcattttc
      421 gctttataag cttctgttac tttaaagcct aactgctctc ttaccttgtt atccggacag
      481 cagccatcaa ttgctgccac gattggcttt cctgtagcca tcgctctgga aatcatattg
      541 gtaagaagat tatcactgat acaatttgca acctttgcgg ctgtattaat tgtcagcgac
      601 ggaataatta caaactgact gtcatctaca atctgtctgc cgttaaccgg agcgccttca
      661 acataaatgg catccggacc aatatcattc ctgatacgtt cttctgtaat tacttctcct
      721 gctgcctttg acagtactgc tgtcaatgtc cagccatcct tttttagttc atttaaagat
      781 gttactgcat ctttataacc aattaaggct ccggagaaaa gaacagtagc tttcttacaa
      841 gcctgtgcgt atcgtaagat gacctggtct gaaatatatt ccacaatcgt tgccataagc
      901 gcatcttcaa attcttttct attcatcatg ccacctattg cttattgcag ttcatggcaa
      961 ttcctaatgg agtaaccagt aaaggttctt tcggcttaat cgtcttaacc cctgtttcct
     1021 tctcaaaaac actttcgaac ttcttaaagc tgcaggcacc gcctactaca taaataacgt
     1081 ccacatcgta tccttcgata aaacgggcaa cgattgctgc catcttttca attaccggtt
     1141 taaccacagg aaataccagc atttcctgtt tcggatcttt tttgattctc tcggcctctt
     1201 caaaggaaca tccaaggctt ccagcaagta ccagagtcat gtgtgttcca cctgtaggct
     1261 catctgcggt aaagataacc tttccgtctt tgagaatact gataccggtt gttccaccac
     1321 cgacatccac gactgctccg tccgtaatac caagaacaga agcggctgct gtaggctcgt
     1381 caatgacatt gactacatcc agtccaacag actcgactac gttggaaatt acctttacgt
     1441 ttccagaaat aattcccggc ggaatggctg tggcagcttc gtaaaactcc actcccatca
     1501 gatcttccag cttggctttc atatttctga ccgctctgga tgcacccatg aaatccacaa
     1561 cgattccatc ccgtacaacc gtggacggat aggaagcccc ggcaattggt gtgttgttgg
     1621 aatctacaac agatactaca atgttggcgg ttccaagatc gacacccaat ctcaaatccc
     1681 cttcataggg acgaaattct tcatttttga taagctccga aaatccaact aaaacgttat
     1741 tgtaatcgtt catgtgatcc ccttatttat tctaatgttc gaataccgaa tcattattgt
     1801 caggattgca tgtgtctgtc tcggtatcca catgcatcca ttgcgcatat ttgtatgtac
     1861 taaatgtacg ttattattga tactatcgca ggaaaggctg aatgcctttc ctgcctgatt
     1921 actgatttat aatccagagc cgattattcc gacttatttg ttatcgttat tatcggtgtt
     1981 cttttttctt ctggatctgc ttcttctatt tcctgttgaa gtctttccct taggagcatc
     2041 tgcctttttg tcagtttcct ttttcggttc agtctcttca gattttgctt cctctgcttc
     2101 tgctttctct actggagtct cttctgctgg agcttctggg gcaggttctt ctgcttttgg
     2161 ctcttctaca ggagcttctt ccactggagt ctcttctaca ggagtttcct cagcaggttc
     2221 ttctgctttc ggttcctcta caggagcttc ctctttgacc tcttccgttt caggttcctc
     2281 tgatgttggc tcttcttcct caggttcttc cactacaggc ggttcaggtg cttcctcggt
     2341 cactacctca gcctttggtt cagtttttgg tttccagttc tttacgagta ccggtttctt
     2401 tgtatctcct tttggacgat aaccttctgc aagagcaatt tctcctccaa cagtctctct
     2461 gttgtctacg agtaattctc tcatgccatc tgccggtctt gcttttaaca gtgtactctt
     2521 tgttccactt aaagaaccgt taactgcttc tgccgctttt ttgcctgctg cgattgctgc
     2581 tctacatgct ccgacgttac cttctacctt tacagtacac attccgccgc cctttgcata
     2641 ttcatatcca agcagtttta cgttagcaga ctttactgct gcatctgctg ctgccacaca
     2701 ggcagctaaa ccaaaggttt cgatgaaacc aagacattta ttgttagaca ccttcacacc
     2761 tcctcacatt tcagaattaa ttaattgtaa agccttaatc cagaactttg aatggcattt
     2821 tctttaccag tcttgcggca ttcgcgccaa tcttccggaa cagctctgtc tgatataact
     2881 taatcttaaa aagaggggcc gctttatcca gcttctcatg ctgaagaaca acgccttctt
     2941 tgctgatacc aacgcccacc cctaatcttg aattcaagct ggcattatgt gcaagttcta
     3001 atacggaact gcaatgctct gcctgaacat cataggggat gccttcctcc tcgattccaa
     3061 gaaggacgct gacaaaatca gcttcagaaa ggtgatcaca gtcataaaaa actttcactg
     3121 aaggtctgtt atcaattact gtattgcttc cttccataat tgtctcctat acatcagcac
     3181 aagacatcgc aagtcctgtt gctaccgcat tacgagggcc ttcgcatccg cgaatgtttc
     3241 cccgaccagc tactatatta tattgtgata atgcatcagt tacgagagtc ggcacctcga
     3301 agtcgagtgc agaaccacct actaatacta caaattcgat gtctcgtaca ttaccggtag
     3361 gactaacctt cgccaatgaa cgaatcgcat ttgttacgaa tacctttttc tttgcattgg
     3421 ttcttaccat cttaatcttt tccatggaat cctgtccctc aagcggaact aactctccat
     3481 cttccttgac taagacaacc tttgcgaata cattcggatc taatggctgt tcaaagaact
     3541 gtacggttcc atcttcatga cgaatatgga aaagactttc aacctttgcg agagaatact
     3601 ttttaatatc ttctgctgta ttgaaatctt ccagtccaag ttcggactga atcagtaaag
     3661 ttaccatgtt tccggccccc gccagatgca cgagctttac attgccgtct ctgtctttaa
     3721 ttgaagcatc cgttgatcct gctcccatat ctactatggc gagtggtaca tttgtacccg
     3781 gtgtagttaa agctccttta atagccatat ctgcctcaac accgccaaca tatacaggga
     3841 tttttaatcg gtctgtcaat tcttccgcga tcatcttcat ctgaagacgg tctgccttaa
     3901 ccatggcagc aattcctact gcactttcta aagaaaattc atttgcgaga ccacctttaa
     3961 tcttctgagg attataagta tctacagcaa gtaaatcctg aattttgata tcttttggat
     4021 gctggtttgt aagatttgac ataacctgac gaactttttc aagcataccg ccggcattgg
     4081 tgccaggttc acctttaata tcttcgatga ctggaacgct atttacagct tccatcatct
     4141 tctcggctcc ctcttctacg ccaacgatta cttttttctt tgcgcctata atctcaatag
     4201 aaccggcagg gatacgtctt tcttttacgt ctccttccgg tgttttaatg acaacggcag
     4261 aacgatttcc gattaacgcg cgggcaatcg gtacaacctg ttttgtatct tccggggaca
     4321 gtttgaataa tgttgcgata ccatatgggt tagagagtac ttcgacaact ccgccaacag
     4381 gtgcaacttc tactgcacat aacattccga gaggtacttt atcaatcata cctacctcat
     4441 caacgatagg aatcttcttt tcaagcctgt tgttaatcaa aacgccatca tcgcgctgga
     4501 caatggcacc tgtaatgtta aatattttgt tatatcggtt aatgagtgca gcggcagctt
     4561 caaaggaaac ttctgccgga ataaccacaa ttacatctcc gccatctttg acagtatcta
     4621 atctgtcgat gcgctgagat attccaacac caatcccaac accccctgga gtattgggat
     4681 tgtgtccaat catagtagat tccgtgataa tagtttcggt aatagtctcc atagcgacat
     4741 caccgataac gggagcggct tcattaatac gaacttcatc aagatcactg atttcaaaac
     4801 caacttcatc aagggcattc ttcagtgact gaaaaactcc gtgtatgttc tgtttcgttc
     4861 ctttgattcc agtggtacct gtaataccac tcgaaaggaa tgtcacattt ttaccatcga
     4921 ttctggcaat cgcagtttcc gttgttgcat tgccaatatc aacgcccgca actaatttca
     4981 cttctcatac ctccgtcgaa atcaatcaac taattatttt tttaaacggt tacgtttttc
     5041 gtaaatgtct gcagcttctt taacgaagtt accacttact gtagcaccgt attcgttgat
     5101 taactcatca ccgattgcat ataattcagc ttttgttgaa cgatatggtc taagagcgtt
     5161 ataaatctca agaagtcttg catcaggtac tgggattaat tcaccagctc ttcttaagtt
     5221 cgttgcgaag aatccacgtc ctgcagattc agcaacctga gcctgtaatt ccagagtttc
     5281 ttttgtgata cggaaatctt ttgcatctaa ctttccatca ataactccct gtaaagttaa
     5341 atcatttaaa gattttccag aagcactctt gattaattct ggttttttct ctcccagtgg
     5401 gtaatcctca accgtaacct tgctttcaca ttcgcaggct gcggcagaac cctgcatgtt
     5461 tttcataact tcctgcataa tctgtcttac taataattcc tgatccacga ttgacacctc
     5521 cgtctattta aatacaactt taagagcttt aggagcctta tctctgtctg catgctctgt
     5581 ctctttgata tgcagtacag cggataaagc ctggaatttc ggtcttgcca tctggtcatt
     5641 ctttacaggt accggatttg gtgattctcc tttagcgtac tgagcagcgt ttttaccgat
     5701 tgctctgtat gtttcaaggt cgatcagtgg gcactgtggg aataactcta agttagacag
     5761 cggtggaagg tctttctgat ggattacagt agtacctttg gactgaattc caattccgat
     5821 gcctgaacct gataattcag cagcatcatg agcgatgaaa gatacatcgg atgttctgta
     5881 aactttaacg attctacagg aaacaccttc ttcttccaga ccagccataa cctcttttac
     5941 aatatctgca tgaggaatac ctacgatatt tgttgtctga gattctccaa aagcaggagc
     6001 taaacctaaa acaacttcgt taggatttgt gcctttttct gcatcaccga tttcagtaat
     6061 ctgcattcca gggcactcat aagtttctcc ctctacagca gaagctgcgg aagtatctgc
     6121 agtattcatt tctttaagaa cttcagcgat aacacttttt aataattttt catcaattgc
     6181 cattatggtt caccttcctt actcgattaa agcttagccg gatctactgc agtacggata
     6241 tcagaaatct tctcccaaag ttctgggctg atctggtaac ctgtcatagg tccttcatag
     6301 cagttagggc tgttaacagc agaaattaca tggaatttat catcaagcat ggaagctgta
     6361 tgtaagtagt caccaacaac tttagctttc tgaatgttga agatagactc agcaacgtct
     6421 tcaaatccac ccttgtaaag agctttaacg aagtcgatac ctgtaactcc acgatcaagc
     6481 atatctgtag cagctttaag gtcagctaca acgtcacggt caggcatatc ctgtgaacca
     6541 cgagcgtatg tggcagcttc aacttcttcg tctgtaattt caggtaaacc taattcacgg
     6601 aacagtgcct gaatagcttt tgcagcttta ttacgtgctg caacaacttc ttcttctctt
     6661 gcaggaagaa gaccagcatc aactcttaag tcacgctgaa ttacgcacca atcatcataa
     6721 tcgtctgcat cccagttgga tcctgcgaac atgttatcat agttcggtgt ggatgaatat
     6781 ccggaacaga tgtagtcagt tcctggaata aactgtggaa tagaacgagc aactctacga
     6841 agatcagagt gtgtaaatga ctggtcatta gaggaagcgt tctcaaggtc aagcatagcg
     6901 gcaattaagt tctcacatgc aacggcgcgg ataccaccag gtacagcggc aggtacaccg
     6961 atacaggata cagaaccatt ctgtgttccc tgaacaccag caccacgagt aacaccgagg
     7021 catctagcct caaggtaaag catagacttt ccttctgcca tacccatctg aacctctgaa
     7081 ccagtaccag atgtaaatct catcttaaca ccacgagatg cgtagcagga tgctaagaaa
     7141 gcttttgacc aaggagtatc atcaccatcc atgaatacgt cttcagttcc gtatacggat
     7201 actgtctcgg cgtaagcggt gtaacctctc atacctaagt caagctctgt agcttcttct
     7261 acagcacact gtgtaaggat accaggacgt ccaacgttag cacctaacat aatagcgata
     7321 gcattaaatg gagcataacg tacaatacct actgttgtct ccatctctgc aaatccacgt
     7381 acagcagctt ctgctgcatc tgctgcgatc tgaaccatgt tatcctttac gtttgtaacg
     7441 tggcactggt tagctggttt taaacgacat ctcatcttgg taatacccat catagcttca
     7501 agtacgctga ggttaccaac gatttctact aacttagcag gtgtaactgc tgtagtatat
     7561 tttaagcact cctgtctgtt aacattaatg tcaactaaca tacgcgcaat ctccagagag
     7621 tctgtagcca ttgcttcttc tgcaaagtca agattaatgg catatcttgc gatgaatgca
     7681 tcaagcatgt cgaattcatc ttttgttttt ccatccattt caacaacttc gccgttgacg
     7741 atcttgatag atggagttgg gtcgaatggg ctgttcatgg caataaagcc tacttctggc
     7801 cattcctttg cataaccatc ctgattaaca ggtctttgat ctaaatactc aaaacgttta
     7861 cttctcacgg tctcaacacc tctcaaattc caattagact atcttttacc ttcaatatat
     7921 atattcaaaa taaaagtatt acaatatcca actgcaggct ctcacccccg ctttgtggat
     7981 atctcttact ctaattccct atatggctct caccccatat aaagaacttt aaaaatcaga
     8041 ttgttaatct tagatatatg gaactgtacc ggattccagt ggttcgtttg gctctaaagc
     8101 tttaagtaac tgcttaccaa cttctcttgc accaatgata gcctgtctaa ctgctcctga
     8161 atctcctgtg aagaagaagt taacctcgtt agagaaggat gttccaccat taccaggtgt
     8221 agcgatagaa ataggatcga ttgtagctgt cttagaagct gtatcggcta atacgatacc
     8281 aatacctgaa ggagctccta cagtgatacc aaatgcttta ccaacaactg cgccgaatgc
     8341 tttctctaag cagtaagaag cacgtgctgt gtactggaac tcaagatgtc cagcggagtt
     8401 tccgtataca tcaccaaagt gttttccaac gaagcttaat gcaacttcta cagctcttct
     8461 agcatcggat acgtcttctg caccaaatac aactaagcat ccatgtccag cgccgccttc
     8521 tgtatcacgt gggcactcga ttaagcaaac ttctgtgttt gtagctttaa cagcttcatc
     8581 acaagcgaag atctgaggac ctgcacctgt acggtctgcg atgataccga ttgaacggta
     8641 cttaggatca atctttaata attcatgaac actgtagtca aggttagcga ttactaaacc
     8701 aattgtatgt cccattgctg ttccaacata ctctgttaaa ccgcaaaggt cttcattgat
     8761 tccctgagga gcttcgcaag ccatgctctg tgcaggagct tctgtgccac ccatcttttt
     8821 cataacttcg tccatgattt tagccatcat ttcatctttc attgaattat acctccatta
     8881 ataattgatc agacaaggac taactctatt gtggtaagat cttttctacg tctgtatgtg
     8941 gtcttgggat tacgtggctg gaaactactg taccaacttt atctgcagca actgtacctg
     9001 cgtctacaga tgccttaaca gctcctacgt cacctcttac cataactgta actaaaccgg
     9061 aaccgatctt ttcgtatcct actaatgtta cgtttgctga tttaaccatg gcatcggctg
     9121 cttcgattgc gccaactaaa cctttggttt caatcattcc taaagcttct ttctgcataa
     9181 ttgacctcct tataaaattc ttatctgccc tgtggttgat ttgttcaggc agaatatatt
     9241 ttggttgatt tacaggatag tatcattata tagcaatttt cacaaaatta cttggctagt
     9301 gcctataaat tttagctttt aaacacatat aaactcatgt atttatttat tttcatgata
     9361 ctttgttgcc atttttacca cagggtagca aatgattttg tatacaaacg ctactatttt
     9421 gcaatatgat caagaatttt attaatatct tctgctgtaa cctttctagg gttagcctgt
     9481 gtacatgcat cagccaatgc acgacgcaca atttcttctc tgtgtttatt aaattcttct
     9541 acactgacgc cacattcgga catacactgt ggacgatcca tatattttaa cagacgctgg
     9601 atctctgcaa tcagattagc cacaccaact ttaggtgtag gagctggcag gccaacgatt
     9661 cttgccatct tctgatactt ctttgctgcg tcattgctgt gttttgcgcc ttctcttgcc
     9721 atatcggcat taaattcaat aacataagga agcactaacg cattggctct tccgtgtgga
     9781 atgtggaaga tagctcctaa agcatgggca ataccgtggt ttacaccaag atttacaagg
     9841 ttaaatgcca tacctgcaag acaggatgct ctgtgcatct tatctcttgc cttaatatca
     9901 taaccattgc ggtaagcgcg tggaagaaat tcaaaagcaa gctctgcagc tttctctgct
     9961 aaacagtcag agcaatcgct cgctgtctca gaaacataag cctcaagagc gtgggtaata
    10021 acatccagtc ctgtatccgc tgtaataaac ggtggcgctg acttaacaag ttccggatca
    10081 aggatagcaa tatcaggcat aaggctctca tcgatcaatg gaatcttaac ccccgtctta
    10141 ctgtctgtta ctacagcaaa ctgtgtaact tcggaacctg taccacttgt tgtcggcagg
    10201 gcaatcagtt tgatcttctt ctgattatca ggattctgct tctcttcaat cttcttagcc
    10261 atatatacaa tagctttcgc cgcgtcaatg gaagaacctc ctccaagagc aactacgata
    10321 tcacagtcct tatcctgcaa aaatgcgata cccctttcaa tcagatccat tggtggatca
    10381 gggactactt cgctgaaaac ggaaacttct ttgcaattag acaatttttt caaaatcatg
    10441 tctgccattc ctgaatctac catgaacttg tcagtaatca ggaccgcatt ctcgtctttt
    10501 tcttcaagaa gtgcgtcgat ggcatcctca ctgaataaaa cttcagtgga aagtttaaac
    10561 cgtttcattt tcctcctcct ttctgtttct gtacttttct ctatactcag atggcgttaa
    10621 tccagtcttc tttttgaagg ccttactgaa gtaattcgct tcattgtacg ccagatccaa
    10681 ggcaatatta agcaccggaa tatctgtgtt gaccagcatt tcttttgcca ggtccatctt
    10741 ccggtctgtc acataggtga tgaaattcac acccatttct tttttgaata tcttacttaa
    10801 ataataagta ctgatattca catggtttgc aacatcctct aaactgatac ccttctttaa
    10861 gtttctctct atgtaatcaa taacggcctt catgccgcct tctgaaagct tacctttgat
    10921 attcatctta tcaaagagaa tgtctaccat cttgataatt tcattatagg catcatgctt
    10981 attattatag agaagatact taatcttaag cttctccatc tgaactacaa gttcgttcgt
    11041 atctgtgatt ccaagttcct cactaatacg cacaactgcc tttgcaacct cctgtagtct
    11101 ctttgatata atattaacat catgctcctc taagtataac tggtctatgt actctcttaa
    11161 aatgtctaca gaagctttgt aagagcattt ttttaattcc atttcgaact ttgaaagcaa
    11221 tttattactc tttccggtct gtcgtccctc tcctaaacgg cttgcaaatg acttcacgga
    11281 ctcaagtaaa acctcttttc tgataggttt gagcaggaaa tcatcaacct tcaactttat
    11341 tgctctgtgt gcaatattaa aatcatcata tgccgttgtt ataataataa cagcctttgg
    11401 aagttttttc cttgcatatt tgataacttc cataccatcc attccaggta tgttaatatc
    11461 taccagcatg agattgatat cttttgaatc aatcatctct actgcctcga agccgctttt
    11521 cgcttctccg acaatttcta catccagaag attctcctca agaaaaatct tcatggaggt
    11581 tctttctaat tcttcatcct caacaattaa tatcttatac aagtcaactc tgcctttcta
    11641 ttcctgtacc aatggcactt ttattgtcac cttcgttcca agagaaggtt tattttcact
    11701 ttcaatggat aacgcatatt catttccaaa ataatgaatc agtcgggaat tgatattata
    11761 aagtcctaca gatccctttt cattatcttt atacgcatcc ccgcgtaaaa cgctgactat
    11821 ttttgactgg gacatgccat caccattatc aataatgtca atgcataaat ctccatcttt
    11881 ctcgcttcca ttcacttcga ccattccacc ggatgcctta ttctcaactg catatttaat
    11941 ggaattctcc acaagtgttg tcagagataa aaatggaagc ttcacactgt aatatgtctc
    12001 cgatatatta atggaatact gcagcctgct tcccaggcga atcttctgaa tcttaagata
    12061 attctgcaca tgggtcagtt cctctctgag cgggcttaat ggatctctgc tctttctcaa
    12121 aatgtagcgc atcatatccg caaacgcata gacaacatcc tccgtcatct tcgcattctc
    12181 aaagaaagca agtcttccta ttgtattcaa tacattaaaa agaaaatgtg gattgatctg
    12241 ataatgtaaa gctttcaact caatatcacg aagagacttc tccatctcaa tacgaagctt
    12301 ctcttccttc atgagcttat aatccttttc gcgaagctct gcatttacct tattcgcata
    12361 ttctctctcc acagaataat tatagctgtc acagataatc tgtgccacag cctcaatctt
    12421 ctccacagac acctctttta cctggctgta gagctcaacc agttcctgat tgtccttcca
    12481 atcctcgctt tgtgtcgtaa tcttctttaa atctgcaaaa tctgtgctgg taacctgacc
    12541 tgccagaaac gctccaacat actgtccctt tatcataatc ggaatcgcaa aatcaattag
    12601 cccagcatga catatgtaca cataagcttt cccaattctt cttgccttcc gtcctccaca
    12661 ggcatcacag taatagcact tttcacgaaa tgcatccagt tcacgaagac gcttgcaaaa
    12721 aggtgtaaaa ttactctgct ttgtaatcgg agttccgttg caatccaccg tcacaaatgc
    12781 cagatctgta gccttcgccc aattatcctg taaagtttga agttctttta catccaccac
    12841 gtcttcaata taaatattat tcttttccgt caatcttctg tcctccaaac atcggcatta
    12901 tcccaacctc atcggtcaga aattaatggt ttttcttcct tctatctttt ttattcaaat
    12961 agcggcaggc cttctctgca caattacagg catcttccgt ataacagtct gcaccgattg
    13021 cctttgcctg cctctccgtc agaaaataac cacctaccat aaaataaaac tgatcccgga
    13081 tacctttcat ctcaaattct tcaacaacag ctctcatatc ttcttcagaa tgcggcatga
    13141 taccacttaa acatacaatc tgagcatgac tgcctactgc ctcctccaga aatcttctcg
    13201 gtgaaacatc cacgcccaga tcaataaccc ttatattctt actctccatc ataatcttaa
    13261 caagattctt tccgatgtca tgtaagtccc cttttactgt tcctattata actgtcccaa
    13321 tctccttttt ggcacgtccg ccactgtaat ggcgcagagt agaaacgccc ctttccaatg
    13381 cgcgggtaac gctcaaaatc tctggcacac caacttcttc tttacgaaac ttgtccgcta
    13441 cctgttccat tccggctaaa aagccatctt ccagaatcat ctgcgggtct gttccctctt
    13501 ctaaagccat cttgaccaag tctgagactc tttttccctg tccccttttc agggaatcaa
    13561 taatttcatc tattgttgct cccattttgc cctccaaaaa tctatcagag tgttctatgg
    13621 ctttatttta tactttttac acctaaaaag caaattatta tcgtatattt tgcaaattac
    13681 ttttcttaaa tataaaattt tactaattta cagcccaaaa tgataaatta ttttattcaa
    13741 acgggcaaga aaaaaggtaa aaaaaggaat tgggtgaacc aataacaatt ttttatgatt
    13801 tgggcttgca aaaaacagat gaaacctgta caccagctcc ttcaccgcca accgtcactc
    13861 cgtagaatcc ccaaatcctt ccatagctct gtactcccaa cttcatcccc ttcactccca
    13921 actggtattc tgggaaatcc tgaattctcc tgattctaac taaatctcgc caaaaaacag
    13981 aaccccaaga tagaatagaa ccgatatctg tgacctcgga gcaaggtttg aacgcgagtg
    14041 cataagcgag cattcaaacc gccgcgacta aagtcacaga tatcggttct attctatctt
    14101 ggggttcgtc tatttcttcg actatttatt tgcgaattac agagtcactt tctccagatg
    14161 ccacatctct tttgcgtact cttcgatcgt acggtcagat gagaacttac
//
