LOCUS       c00001_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKGBBFMB_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:08:54
            Original ID  :: gnl|Prokka|OKGBBFMB_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 660764
            Orig. end    :: 683992
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[670764:673992]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             341..556
                     /locus_tag="ctg1_630"
                     /transl_table=11
                     /translation="MITYKLNHTPKDGFNTFGISAFCGKKLIKSVSGISESFREMTELV
                     EMCNELELELCQLDDIIEDYLTDFTL"
     CDS             647..1525
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_631"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-12, bitscore:
                     43.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MICNLCPRKCGAVRTAHSGNGFCKMGELPVVARVAPHYGEEPCIS
                     GTKGSGTVFFSGCTMRCVYCQNYEISNEDGGRTITPERLAECYKELEDKGVHNINLVTA
                     DHFAHAVVKSLEIYKPRIPIVYNCSGYTSPKTLSMLDGLVDIYLPDFKYADDFLAVKYS
                     SAPNYVNTAVAAIHEMTFQVGLPQFDDDGIMKKGVIVRHLILPAHTKNSLEVLDIVKRR
                     FGDQVLLSLMCQYIPMGKVSDREFSRINRKITRREYDKVKLEMMRLGIDGFTQELSSAD
                     ESYVPEWDFEG"
     CDS             complement(1851..3584)
                     /locus_tag="ctg1_632"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     E"
     CDS             complement(3599..4084)
                     /locus_tag="ctg1_633"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(4106..4894)
                     /locus_tag="ctg1_634"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAERSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(5017..6309)
                     /locus_tag="ctg1_635"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             7046..7363
                     /locus_tag="ctg1_636"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             7376..9700
                     /locus_tag="ctg1_637"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYAVLAACFVATLLSGYKVFIKGAKNI
                     LKLKIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAAAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTLRPEAKEVISQLKTLGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_638"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-41, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKIYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_639"
                     /sec_met_domain="ALS_ss_C (E-value: 2.2e-28, bitscore:
                     93.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRVNTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_640"
                     /sec_met_domain="IlvN (E-value: 4e-82, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.2e-59, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13615..16020)
                     /locus_tag="ctg1_641"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGRKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCISADGKSFTSGYDSKGTTVKYIA
                     APEISKLENVNGGVKITWNKVSGASKYRIYQKNSSDWFRVSDTTSNSIVDKSVDVGTYT
                     YTVRCISDDGKSFESGFNPKGSSIRYIQAPKILETNVVNGGIKVIWETENNTNYRLYCK
                     TEGKGWTKVCDTKTGVVTHKNLQPNKTYTYTVRAISSDAKKYLSGYDPVGMSAKYVATP
                     KISKAEYTYDGIKLAWNKVAGAEKYRVYYKDATGWNKLIDTKGTSYLDKGLVSRELSVK
                     DSSVNGQYIYTVRCISSNGKVFQSGYDTKGVKSALYNNGCPQIYNIDTMHGGITLNWEA
                     TADKISKYRVYIKQNGSWKKLADTTDNWYTHKNVKAGQTYTYTVRCVSKDGKKFTSTYN
                     PSGVAFKYKTTNKTRDAYIDYLLKHESEWLPELKVGDIALAGVQFTDLDFDGVPELIAQ
                     EAGDKEYYLNARVYTFKNGKLSLVGFDNSMTYIQNRLTYLYDKSAKRYVINSADLSTSN
                     PDRYLDCENYTLSYDGNLISAHPYSSYHLALENWGLDYTYYVHGRTSKQVYNAANLSTL
                     DNCVNAHMYSQFVYCSVDGYPKLWNRFTTDQKRQYLTDSYNAFSYDKY"
     CDS             complement(16217..17239)
                     /locus_tag="ctg1_642"
                     /transl_table=11
                     /translation="MKKLLTALIAFVMCFSVVTTAFAATPDETSDPDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTVSYPRDCPVLLYK
                     NNKVYTLSDAYETGVIDDDMLYELYVWGNLWGKIDVTPKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDETVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TSATKPVSTSDTATNDTPSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK
                     "
     CDS             complement(17433..18110)
                     /locus_tag="ctg1_643"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDEISESDVASEIRQVMIDT
                     YYGGKEPEYLNIEIVGSTSDGGVYFMHNEGFSLDYSIEETIGDYTYHYNHNDDVMLYKN
                     GNVYSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDT
                     TSATSATKPVSTSDTATNDTPSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRN
                     HFE"
     CDS             complement(18305..19708)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_644"
                     /sec_met_domain="HMGL-like (E-value: 5.1e-48, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.1e-53, bitscore:
                     177.3, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPQFQKKIIGDKKI
                     IKGRPADQLKPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             complement(19739..20104)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.4; E-value:
                     5.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_645"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.5e-20, bitscore:
                     66.4, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVIKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
     CDS             complement(20143..21456)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Btheta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_646"
                     /sec_met_domain="CT_Btheta (E-value: 3.3e-66, bitscore:
                     219.1, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEKINQAKAEIAATSAYKTITAFFDADSFCEIDAFAKSGEGFA
                     EVVAGFGTVEGMPVYAFAQNSDICGGAMSKAQAAKLKKLYGLALKTGAPVVGFYDSVGG
                     RLKQGTELLAGCGDVLNAAASLSGVVPQISVVLGTCLGTNALNAASADIVIMSKDAQLS
                     LSVTGKHSDAAYNAENGIASIVCDDADKAIKTAKELILYLPSNNLTMAPQSFEEAPAED
                     GCGCVVSRTVDGNSIVKLFNDYGKEANVRFARLGGQVVGIVVTKGKELGCKSANKVAKF
                     VRFCDAFSLPVVTFVNCPGFESIKSATKASAAYAEATTVKISVVTGKAIGSGYVALAGT
                     GANADVVYALPDAVISPVNVEAAAFIMAPEVMNVATDKQAEVAQKFADENLSAYNAAQN
                     GYVDGIVEEAQLRQTLISALDMLSGKRVSTLSKKHSTI"
     CDS             complement(21687..22436)
                     /locus_tag="ctg1_647"
                     /transl_table=11
                     /translation="MAKIEPIRLQKFIAQCGIASRRKAEELILGGHVKVNGKTAILGDK
                     VLPTDKVFVRGKRIVVPKGGNYRYIMLNKPRGFITTMNDERGRKCVAQLVENVGERVYP
                     IGRLDKDSEGMLVFTNDGDFANKVMHPKNNVYKIYRVTVRPSIDEDQLVKLETGVELDG
                     RKTAPAYVRVIHKEQGRVVLEMILHEGKNREIRRMCEAVGLEVARLKRTQIGGVKMGML
                     KQGDWRDLTEQEVKKLLANPFLNGKQL"
ORIGIN
        1 aagactgaca caaagcaatg attaactatt gttattgcaa tatttcagca gttaactgtc
       61 gccgatatat tatttgccgt ttgccgaaaa atctgactgc actgaaatta tataccatat
      121 gtaatacttt gttacatatt attaagattt tatcgaacta aagtttttat tgttataaaa
      181 ttctttaact gaggtttaca ttcatttgtc attatgtaca atttattact gatacatcac
      241 tatttgttta caactcaaca atatttttgt aataatattg acaatatcgc aacataatag
      301 tattattatc ttgtgaccgg ttatcatccg gaggggaaaa atgataacct acaaattgaa
      361 tcatacgccc aaagacgggt ttaacacctt tgggataagc gcattttgcg gcaaaaagct
      421 tataaaatcc gtgtcgggaa tcagcgaaag ctttcgtgaa atgacggagc ttgtcgaaat
      481 gtgcaacgag cttgagcttg aactctgcca gcttgacgat atcatcgaag attatcttac
      541 tgatttcaca ctttaatttg caaagacttt aacttttgtc ataatcgtgg tacaatagtg
      601 tttagtgttc tatcagacat tatatatcag acaataaggt gatatcatga tttgcaattt
      661 atgtccgaga aaatgcggtg ctgttcgtac tgcacacagc ggaaacggat tttgtaaaat
      721 gggagaactg cccgttgttg caagagttgc tccgcactat ggcgaagaac cgtgcataag
      781 cggcacaaag ggcagcggaa ctgttttctt ttcgggctgt acaatgagat gcgtgtactg
      841 ccagaactac gaaatttcaa acgaggacgg cggaagaaca atcactcccg aaagacttgc
      901 cgaatgttac aaagaacttg aggacaaggg agtgcataac atcaaccttg taacggctga
      961 ccattttgca cacgctgttg ttaaaagtct tgaaatttac aaaccgagaa ttccgattgt
     1021 atataactgc agcggataca caagtccgaa aactctcagt atgcttgacg gacttgttga
     1081 catttatctt cccgacttta aatatgcaga tgattttctt gcggtaaaat actcttccgc
     1141 accgaattat gtcaacacgg ctgttgcagc aattcacgaa atgacttttc aggttggtct
     1201 gcctcagttt gacgatgacg gcattatgaa aaagggcgtt atcgtaaggc atctgatttt
     1261 gcctgcccac acaaagaaca gtctcgaagt gcttgatatt gtaaaacgca gattcggcga
     1321 tcaggttttg ttaagtctta tgtgtcagta cattcctatg ggcaaggtca gcgacaggga
     1381 gttttcacga attaaccgta aaatcacacg cagagaatat gacaaggtaa agctagaaat
     1441 gatgcgactg ggaattgacg gctttacaca ggagctttct tccgcagatg aaagctatgt
     1501 ccccgaatgg gattttgaag gatgattttt tgattaatgg aactcttgta gcggcgaacc
     1561 gtgttcgcca atcatttcgt atgtaaatac gaaatgagca aaaaacaagc tttccataat
     1621 aatccaatta attttattgg aacatatgta tcctgtcgaa acgattttac aatcgttccg
     1681 attggcgaac gaggttcgcc gctacgaatg aatacacaat tttcttctta ttaaaatcta
     1741 tgtgtttgaa catataatat catcagggtg ggcgtccaat gaacgcccct accgattaat
     1801 tttcaaaaac aaaacggtca agaaacattt tttagtttct tgaccgtttt ttattcaacc
     1861 gtttgtgacg gttttacata cagggttttg ttgttgacat aaatcaccat accaggtttt
     1921 gagccgtttg gctttgacac atagcgaaca agtgtgcagt caacgggaac ctgactgctg
     1981 tttctcgcct tactgtgata tgccgcaagc cgtgccgcct cgtagattgc cgtgtcggaa
     2041 atctctttgc cgtccgaaac aacaattaca tgagaaccgt gaatgtcctt tgtgtgcagc
     2101 cacatatcgt tctttgacgc tgttttcaaa gtcagcttat cattctggcg gttgtttctt
     2161 ccgacaagga ttttaaaacc gtcgcttgat tcaaattcga gtggcggcaa agttgtctga
     2221 cggggctttt tgcccttttg aaccttgaga tagccctgct cggtaagttc ctcacgaatt
     2281 tgtgcaaggt ctttttcatt ttccgcacgg tcaaccgtat cgagaaccga gttaatataa
     2341 tcaagctctt ccctgccctt ttcaagctgt tctttgagca taatttcggc atttttagcc
     2401 ttgcggtaat ccttgtaata cttctgagca tttgccgaag gtgagattgc cggattaagc
     2461 tttatgcgta aaattgcgtt gttctcatcg taaaagtttt caacatcaac atactccgca
     2521 ccacgctcaa tgcgatagat atttgcctgt aaaaggtcac cgcatatgcg aagatgctca
     2581 cggtctgcac agcgttcaag ctcactcttc tgctttgcaa tttttcgggc aagcctttca
     2641 agtgtgttgt tcaaaagctt tgtaaggctt tgtgatttca ccctcattct gtcacgactg
     2701 tcacgagcct catagaatcc gtcaagcaaa tcggagaagc tttccttact ctcaaccttt
     2761 gcgaaatcgc cgtactgctc aacattcata aagcagaagt ccataggctt gccgtcctca
     2821 cgataaacca caacaggctt gcccgaacaa tcgctgcaaa cgcttttcag cttttcaatt
     2881 tcaactgcga gtcggtcaaa aagcacaccc tcaattctgt ttgttgcgcc ctccataacc
     2941 ttgtattcaa tctcacggca tacaatcgga gaaacaccct caattgtcct taacagcgcc
     3001 ttgttaagtg gcatttccgt gtcaagattt tttacggctg tacacacatc aagcaccgaa
     3061 catttaagga gattcagctt gttctgcgat tcgggaagtt cgtattttat attcggcagt
     3121 acaagtcttt tactgctcat tgtaagatct acacgcttga gtgaatcgat gatgacgccg
     3181 tttgaatcga caataattat gttgctgtac atacccataa tttcgcatac aacagttatc
     3241 atcacagtat cgccgagttc gttcacgcac tcgaaatcga gcataagaac acggtcgcaa
     3301 ccgttctggc gaagtcccac aagctttccg ccgccgattc tttttcgcaa aagcatacag
     3361 aacatcggag gttgtgcagg attttcgggt gttgacgaac aaaagttcac tctcggtgaa
     3421 tttgctcgtg cagaaagcaa cagctttttg ttgccggaaa aggttctcag cccgaacaca
     3481 agctcctctc tgttcggctg ataaatctgc gacacccttg caccgagagc ctctttttct
     3541 atttcacttt taatatgtct taaaaaaatt ccgtcaagcg ccatagtaac tccgtaaatt
     3601 atttgtgata tttaccgttt gatgaaatct caaacgcacg gtaaatctgt tcgcttaaaa
     3661 tcattcttgc catttggtga ggaaaggtca ttctgctcat tgaaagacgg acatccgccc
     3721 gttttttaac cgattcgtca agtccgtagc tgccgccgat aataaaatca acggtgcttt
     3781 ttccgcttac ggacgcattg tcaatcagct ttgaaagctc ctcactcgac atagactttc
     3841 cctcaataca cattgcaaca acataatccg aaggcgaaat tttctgcatg attcgttttc
     3901 cctcagagaa aataacctca tcaatctgcg acctattcgg tatgttgctc ttaatgcgtt
     3961 cttccgaaag ctcaataata ttgaatttac aaaatgcggt caagcgtttt gcatactctg
     4021 caattgcatc ggtaaaatat ttttccttga ttttgccgat acaaattatg ttaatcttaa
     4081 tcatatttct cttgtttgtt taaggttaaa agatgatggc ttttgttgtg cttacactcg
     4141 gagcaacatc aagcgaataa tcgcttttgt acttcattcc gtttgatgtg agcaggtcta
     4201 cggatgttga cattgcaagc ggaacggtat tattttcttc gctgagatgg ccgagcataa
     4261 gtcttaaagt tcccttttca acaaggttaa caagttcttt tgcacaagcc tcatttgaaa
     4321 gatgtcctct gtttgaaagg attctctgct ttagcggata aggataaaat ccgtttttga
     4381 gcatattaat atcgtgattt gactcaagca caacaaagtc gctccgctct gcggcagttc
     4441 tgacatcggg caacataacg cccatatcgg ttgctataag tgcggatttt ccgtcgggag
     4501 cagtaacacg gtaacaacag ctttccgccg catcgtgggg ggtgtcaatt cgctgaacac
     4561 gcatattgcc gattacaacc tcgtcagtta taacatctgc atctgtgttt ggatcaagtt
     4621 tattacctgc cctcaaagca ttgagcgtac caaggcttga atacacctta aagccgtaac
     4681 gctttgcaag cacacgcaac gcactgcaat ggtcagtgtg ttcgtgagtt ataaaaaccg
     4741 ccccgatact gcccatatca agtccgtttg caagcatggc attttcaatc tgcttacatg
     4801 aacgacctgc gtcaatcagt acgccttcgc ttgccgaacc tatgtagtag ctgttaccct
     4861 tacttccgct gaacagcggt actgctcttg ccaaaacaat caatccttat ctttagtata
     4921 acgaatatga taacacaaat tttaaaattt gtaaattatc tcacaaaaaa gccgttctca
     4981 caaagaaaac ggctttgatt tctaattaaa ttttagtcag gcaccgagct cctgctcgtt
     5041 gtctcctgta aaatacacct ttttgatatc tgcaccaagt cctctgaact tttcaacaac
     5101 atcttcatat ccacgctcaa tgaactgaat atttgaaatc tctgttgtac cgttaatttc
     5161 aagagcggca ataatcatag ccgcacctgc acgaaggtcg gttgccttaa cgggagccgc
     5221 tgtgagcgga acaccgccct caatgattgc aagtctgccc tcaacagaaa tctgcgcacc
     5281 cattctgata agctcgctga catactgata gcgattatcc caaacattct cgttgatgat
     5341 gcttgttccg ggaacgctca taagcaatgc ggcaaactgc ggctgacagt ctgtcgggaa
     5401 gccgggatgc ggcattgtct tgatattaca gcgctttagc ggagcagatg acgcatcaac
     5461 cttgagagcc tcatcatatt ccgtaatctt aacacccatc tcacgcagct ttgcgctgat
     5521 tgattcaaga tgcttcggtg taatattctt caccgtaata caacctcttg ttgcggcggc
     5581 ggcacacata tatgttcctg cctcaatctg gtcgggaata atcgaataag taatgccgtg
     5641 aagatactca acgccacgga ttttgataac atccgtacct gcacccctga catccgcacc
     5701 cattgaatta aggaagttcg caaggtcaac aatatgcggt tctcttgcgg cattttcaat
     5761 aatggtctgc ccctttgcct ttgatgcggc aagcataatg ttcattgttg caccaacgga
     5821 cacaacatca aggtacacat gtgtaccgac aaggctgtcg cattctgcct ctataatcgc
     5881 accgtcaaca agctgagttg tcgcaccgag agcctcaaag cctttaagat gctggtcaat
     5941 cggacgcacg ccaaagttac agccgcccgg aagagccacc ttagccttgc cgtacttgcc
     6001 caaaagtgca ccgagaagat aatatgacgc tctcatacct cttacaaggt cggtcacagc
     6061 attgcatgtg cggatttttg taggatcaat atataaggac gaacggttga ttcgtcttac
     6121 attagcaccc atctgctgaa gaattctgct gataagtgat acatcgctga tgttaggaat
     6181 attttcaatc tggcacggtt catcacaaag aataactgcc ggaataattg caacggctgc
     6241 atttttcgca ccgctgattg tcacttcacc cgataatggc tttccgccgg taactacgaa
     6301 cttctccaat tgttacaccc caattaatgt gtagaagata cttttaacta aataagctaa
     6361 atatctgaaa atgtatatct atatagtgta taagtaaaaa tcaaaaatta tacgaatcta
     6421 aaattcataa tgagaactaa tttgttacat tttattaaaa acgaacccac tcggttacgc
     6481 agatgtaatt taacaattct cttacagaaa atgatactac aaaattgtag taaagtcaac
     6541 ggaataataa aactgtaatc tatttttggg caagttgtac tcaaattatt aatttgttgc
     6601 tttttttgtt tttaatataa ccaaccatgc tttttaaaac cgttttttcc taaaaagaag
     6661 taattaatca aagcgatttt ttgtaaaatt attacaaatt gaaacaagtg ttattttcgt
     6721 gttatcatca gacatctgag tattttccaa ttcaaattga acacagaaaa atatcgttcc
     6781 gttattccta tgataatttt acaccttcaa tcttcttttt tcaaatttaa aattaacttt
     6841 ctatgactat actatatata cttcccaaac ggacacaata aacaagtgaa actttggggc
     6901 aaaaaaactt gaaaaacatt acattttttc gtgtgtgtct attgactttt taaaaaggga
     6961 atgctatatt ataattaaca tatgagcata tcttcatatg ttcaagtata acttttaacc
     7021 tgagagaaaa ttaaagggga cgcctatgga aaacaaagaa aaaacaacca ctcccgaaat
     7081 gcccgacatt gatgtgctgt ttgagcttgc agaccttttt aaggttttcg gtgattcaac
     7141 ccgacttcgc attatgtaca ccatttcgga aaatgaaatg tcggtgctca acattgctga
     7201 agctctcagc atggagcaaa gcacaatttc ccaccaactg cgtgtgttaa ggcagaacaa
     7261 gctggtgcgt gttcgccgtg aaggaaagca gatttattac agccttgacg atgaccatgt
     7321 gaaacgaatc atcgaaatgg gacttgacca tgttcttgaa taaggaggga gacatatgag
     7381 gtacaaatat cagcttgaca atctcaactg tgctcattgt gcaggcaaga ttgaggctaa
     7441 aattgcagaa acagacggct ttgaggatgt aagcttcaat tttgcgacaa aacttctcaa
     7501 cttcaaaagc gaaaagcaga atcctgtttc cgaaattcag gcaatttgcg acagcattga
     7561 ggacggtgta accgttgttg acaaaactcc gaaaaccaat ctcaaaaaat acacctacac
     7621 tttagacaat ctcaattgtg ctcattgtgc gggcaaaatt gaggctaaaa ttgcagaaac
     7681 agacggcttt gaggatgtaa gcttcaattt tgcgacaaaa cttctcaact tcaaaagcga
     7741 aaagcagaat cctgtttccg aaattcaggc aatttgcgac agcattgagg acggtgtaac
     7801 tgttgttgac aaaactccga aaaatgatat cacaacaaag gcagaacccg aaatcacaaa
     7861 aaagaaaatc aaccgtgaca caatcttcct tgcaatttca attgtacttg ctgtagtgtc
     7921 cgaaattctc caccttacac ttgacggtgt tacggctgtt cattatgctg tactcgcagc
     7981 gtgttttgtt gcaacacttc tttcgggtta caaggtattc atcaagggtg caaaaaacat
     8041 tctaaagctg aaaattgacg aaacaacgct tatggctgtt gcggtaattg cggcattctg
     8101 tcttggcgat tttgttgagg cggcaatggt aacaatcctc ttttctatcg gtgaaatttt
     8161 tgaggatcga gcagttgacg catcccgccg tgacattgaa aagcttgcaa acattcgtcc
     8221 cgatacagca acaattattg ttgacggtgc ggaacagatt gttcctgccg aaagcgttga
     8281 aatcggaagt atcattgaag tcaagccata cgaaagagtt ccgcttgacg gcattattat
     8341 taaaggtaaa acgactctcg acacatcggc tctcacaggc gaaagccttc ctgttgatgc
     8401 aggcgagggc agtgaggtac tcagcggcgc aatcaacggc agtaacctta ttaccgtcaa
     8461 aaccacaaaa catttcggcg acagtaccgc aacaagaatt cttcagcttg ttgaagatgc
     8521 cgccgctcaa aagggcaaca gcgaaaagct tatttcaaga tttgcctctg tttacacacc
     8581 ggttgttgta ctcattgcag ctgcaatcgc agtaattcct ccgctttgcg gactcggagc
     8641 tttcagcgaa tggctatacc gtgcgcttgt ttgtcttgta gcgtcatgtc cgtgtgctat
     8701 tgttatttcc gtacctctct cctactattc gggtatcggt gcggcatccg aagtcggtgt
     8761 actcatcaag ggcggaaaat atattgaggc tcttgcaaaa gcagacacat tcgtattcga
     8821 taaaacaggc acgctcacaa gcggcaagct cagcgtaaac aaggttaata ctgtcggttc
     8881 atacagtgct gacgaagttc ttgctcttgc cgctgcaagc gaaaaatatt ccgctcatcc
     8941 gattgcctcc gcaatcagag agaaggcaaa cggtcttgaa cttcccgagc tttccgacta
     9001 cagcgaaagt gccggtcacg gaacaagcgc agtttacaac ggcaaaacta ttcagtgcgg
     9061 cggttcaaag attctttcgg acgaacagaa gaagattgca aataaagacg attctgtttt
     9121 cgtaatttat gacggtcagc ttatcggttc gctcaatgtc agcgatacgt taagacctga
     9181 ggcaaaagag gttatctcac agcttaaaac gctcggtgtc aagaacacgg taatgctcac
     9241 aggcgacaga caacagcctg ccgaaaatgt taaaaacgaa ctcggacttt ccgaatgtca
     9301 cgcagagctt ctccctgctc aaaagcttga gcttttcaag ggcttgaaat caaaatccaa
     9361 gggtgcttgc tttgtaggcg acggcatcaa tgatgcccct gttctttcgg caagcgactg
     9421 cggtatcgca atgggattcg gcagtgaagc cgctattgaa gcgtcagacg cagttcttgc
     9481 atcaggcaca ctcaaacagc ttccaaaggc aattaaaatt gcaagaagtg ttatcaacac
     9541 tgtcaaaggc aacatcatct tcgccctctc aatcaaggct cttgtaatca tcctcgccgc
     9601 attcggtctt gcacaaatct ggatgtccgt tatcgccgac acaggcgtca gcgtagtctg
     9661 cgtcctcata gccgcaagac tcctcaaaaa gaaatattga ttttctcaac aatcattact
     9721 gttcccgagc aggtaaaact gttcgggaat tttcttgtta ttactcttat acagatactt
     9781 ttttggtcag cattttgctt ttgttgttaa tcatttatta tatctttttc aggcgatgac
     9841 agaataattt aaaatcctgc aaaaaattta atttatggtc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag taaaagggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc cgggtgcggc
    10081 tatctgccca ttttacgata aaatttacga ctcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacagg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga acactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg tatcaagctt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt atttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagcgcaa tgttccgctc aaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgctgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaga tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc acttgcagta ggtgttactc aggacccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aagctcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaattcat
    11881 cagccgtgag cttgtattaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aggcgaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgcgcaa gccgcgtcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 caaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cagcagaggc
    12421 tgcaaagcag gctgacatca ttatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaatatg cttatgttcg ctcacggctt
    12541 taatattcac ttcggttgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggaccg ggtcacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgcagtt gagcaggatg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgagcagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg caggttacga cccaagaaac gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaaa gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagct
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaagtta gtttgatata
    13261 ttcaaacttc tgtcacccga gcattacata gtacgaattt agggtagctt gattttcaag
    13321 ctaccctttt tgcgagtacc tcgctcgtag ttcgtgtagg tagtttgtga taatttacaa
    13381 ctacttgttc ccgagcttaa catagttata attttcaagc tacccttttt gcgagtacct
    13441 cgctcgcagt tcgtgtaggt agtttgtgat aatttacaac tacttgtttc caagcgtgac
    13501 atagtacaga ttaacggttc agtcaatttg gctaaaccgt ttttgttgcg caataaaagg
    13561 gttcagcttt ttacggctga accctttacc gttataattt attactttta ggaatcaata
    13621 tttatcatat gaaaatgcgt tgtaagaatc ggtaaggtac tgtcttttct gatcggttgt
    13681 aaaccgattc caaagttttg gatagccgtc aacagaacag taaacaaact gactgtacat
    13741 atgtgcattt acacaattat cgagtgtact caagtttgca gcattataca cttgtttgct
    13801 agtcctgcca tgaacataat aggtgtaatc caatccccaa ttttcaagag ctaaatgata
    13861 agaagaatac ggatgagcac ttataaggtt gccatcataa ctcaatgtat agttttcaca
    13921 atcaagataa cgatcgggat tgctggttga taaatcggct gaatttatca catacctttt
    13981 agccgattta tcgtataagt aggtcaatcg attctgaatg taggtcatag aattatcaaa
    14041 tccaaccaat gaaagctttc cattcttgaa agtatatacc cttgcattca aatagtattc
    14101 cttatcccct gcttcctgcg ctataagctc aggaacaccg tcaaaatcaa ggtctgtaaa
    14161 ctgcacacct gccaaagcaa tgtcccccac cttgagttca ggcaaccact ccgattcatg
    14221 tttaagcaga taatctatat atgcatctct tgttttgttg gttgttttat acttaaacgc
    14281 aacacctgac ggattatagg tacttgtaaa tttcttaccg tcctttgaca cacatcttac
    14341 agtataagta taggtctgtc ctgcctttac atttttatga gtgtaccaat tatcagttgt
    14401 atcggcaagc tttttccacg aaccgttttg cttaatataa actcgatact ttgaaatttt
    14461 atcagcggta gcctcccaat ttaaggtaat tcctccgtgc attgtatcaa tattataaat
    14521 ttgcggacat ccgttgttat ataatgcact ttttacaccc tttgtgtcat aaccgctctg
    14581 aaaaactttg ccgttacttg aaatacagcg aacagtataa atatactgac cgtttacaga
    14641 actatctttt acgctgagtt ctcttgaaac aagtcccttg tcaagataac ttgtaccttt
    14701 tgtatctata agtttattcc aaccggtagc atccttataa tatacacgat atttttcagc
    14761 acctgcaacc ttattccacg caagcttgat accgtcatat gtatattctg cctttgatat
    14821 tttcggtgtg gcaacatatt ttgcgctcat tcccacaggg tcataaccgc tcaaatactt
    14881 tttagcgtcg gaactgattg ctcttacagt gtatgtatag gttttattcg gctgtaaatt
    14941 tttatgtgtc acaacacctg ttttggtatc gcatactttt gtccagccct taccttctgt
    15001 tttgcagtac aatctgtaat ttgtattgtt ttcagtctcc caaatcacct taataccgcc
    15061 atttacaaca ttggtttcaa gtattttagg agcttgaata tatctgatac ttgagccttt
    15121 tgggttaaat ccactctcaa aactctttcc gtcatcactt atacacctca cggtataagt
    15181 ataggttccc acatcaacag atttatcaac tatagaatta gaagtcgtat ctgatactct
    15241 gaaccaatct gacgaatttt tctggtaaat tctatacttt gatgcaccgc ttactttgtt
    15301 ccatgtaatt ttcacaccgc cgtttacatt ttcaagcttt gaaatttcgg gggcggcaat
    15361 atattttaca gttgtcccct ttgaatcata accgcttgta aagctctttc cgtcagcaga
    15421 aatacatctt acagtatagg tgtaattcct gccagatgaa acatccttgt cgatatatga
    15481 tgttgaagtt gtatcgacca ttcgtgtcca acctttacgg cccttgtagt aaactctgta
    15541 tttagttgca ccgcttactt tgccccaaga gattttcaca ccgccgttta cattttcaag
    15601 ctttgaaatt tcgggggcag caacatattt tacagttgtc ccctttgaat cataaccgct
    15661 tgtaaagctc tttccgtcag cagaaataca tcttacagta taggtgtaat tcctgcccga
    15721 tgaaacatcc ttgtcgatat atgaggttga agttgtatcg accattcgtg tccagccttt
    15781 acggcccttg tagtaaactc tgtacttagc cgcaccattc actttgttcc atgtaagctt
    15841 tacaccgccg taaacgcttt cggcttttga aattttcggt gttgccaagc ttgcccttgc
    15901 aacctgtgca tactgcacgg gtgtgttaag cggttcaacc gcatttgcag aaactgccga
    15961 aaccgcaacc gcagacatcg acattaccgc cgccatggct ataggtaaaa actttttcat
    16021 atctatccct cgctttgttc aaattctacg cattacaaaa taattcgttt atttttttat
    16081 gcaagttaat tgtaacatta aatgatataa aaagcaatac atcttgataa actatcacaa
    16141 atttttaagc taaaataaat aaaccgttca caaaagcgag aacggtttat tttatatatt
    16201 ctgttgatgt tttgaattat ttaaaataat ttctgcgttt tgcaaaaatt actgcacaac
    16261 ctgcaagcat tgcaacaaga agaattacag caacgctgtt ctgtcctgtc tgtacagcac
    16321 cgctgttgtt ctgtgaattg ctcggcgtgt catttgttgc tgtgtcgctt gttgaaacag
    16381 gcttagttgc cgaagttgca gaagttgtat cgggtactgt tacaggttcg tcaactgttg
    16441 caaccgaagt tgtaggctca gtaggaacag ttgtattcgg tttattagat tccaaaccaa
    16501 aattcatttt tgacaattct tcaagaatac tatcgtcaat aactccgctt tcataagcct
    16561 ctttaattga gtaaacattg ccattcttat aaagcataac atcatcgcca tggttgtaat
    16621 aataagtata gtcgccaatt gtttgttcaa tcataacgcc taaactcata aagggtatat
    16681 ttctaaaaca tactgtttca tcacttgtag aaccaacaat ttcgacattc aaatattcag
    16741 gtgctttgcc attgtaatat ttatttataa ttacacgctt tatttctgaa aggagagctc
    16801 tatcttcacc ctttggggta acatctatct taccccaaag atttccccaa acatataatt
    16861 catagagcat atcatcatca attacacctg tttcataggc atctgacaag gtatatactt
    16921 tattattctt gtataacaaa acgggacaat ctctcggata agaaacagta taatcaccta
    16981 tatcgaattc cacttcatct gtccagtgtg taaaactatc cataaaatcg aaatacacgc
    17041 caccgtcact ggctgtacca tatattctta cttcaataaa atcaggcttt tcatcgccat
    17101 aatatgtatc taacatagcc tgtttaatat ctgaaatcaa gtctggatca gaagtttcat
    17161 caggtgtagc agcaaaagct gttgttacaa ccgaaaagca cattacaaat gctatcaatg
    17221 cagttaaaag ttttttcatt tttatttcct catcttttat ttattctatc tgtaataatg
    17281 gtatacgcaa cagatattca atttacatca ttataccgct aaaatatatg taatgcaata
    17341 tagttgctaa aaattcacat aaaataatca gcaaaataaa aaccgttctc aataacgaga
    17401 acggctttta tagggattat ttgatttgta aattactcaa aatgatttct gcgttttgca
    17461 aaaattactg cacaacctgc aagcattgca acaagaagaa ttacagcaac gctgttctgt
    17521 cctgtctgta cagcaccgct gttgttctgt gaattgctcg gcgtgtcatt tgttgctgtg
    17581 tcgcttgttg aaacaggctt agttgccgaa gttgcagaag ttgtatcggg tactgttaca
    17641 ggttcgtcaa ctgttgcaac cgaagttgta ggctcagtag gaacagttgt attcggttta
    17701 ttagattcca aaccaaaatt catttttgac aattcttcaa gaatactatc gtcaataact
    17761 ccgctttcat aagcctcttt aattgagtaa acattgccat tcttataaag cataacatca
    17821 tcgttatggt tgtaatgata agtatagtca ccaattgttt cttcaattga ataatcaagg
    17881 ctaaagcctt cattgtgcat aaaatatact ccgccgtcac ttgttgaacc aacaatttca
    17941 atgttgagat actcaggctc tttaccaccg taatatgtat ctatcatcac ctgtctgatt
    18001 tctgatgcaa catccgattc tgatatttca tcaggtgtag ctgcaaaagc tgttgttaca
    18061 accgaaaagc acattacaaa tgctatcaat gctgttaaaa attttttcat ttttatttcc
    18121 tcacctttta tttattctat ctgtaataat ggtatatgca acagatattc aatttacttc
    18181 attataccgc taaaatacat gtaatgcaat atagttgcta aaaattcaca taaaataatt
    18241 ctgctcaaat gaaaatgcca ctttcatagc gaaagtggca taaatgttaa ttttagttgt
    18301 caaatcaaac agggtgaacc atatttttct tgtcaagctt gtcgccgttg atgccaacct
    18361 tggcatttct tctcttttca aagaagtcga gggcaacctt cgggaactgt gcataagaaa
    18421 gaacatcctc aggctgttca atccactgct caatctcgcc acggagctta tcaagctcag
    18481 gcttaagctg atctgcagga cgacctttga taatcttctt gtcaccgata atcttcttct
    18541 gaaactgagg atcaatcggc attggagttg taccgtactc accggcaaca agtcccttga
    18601 actcgtttgt gcacattgag tagcgcttgc ctgtgattac attgaataca gcctgtgtgc
    18661 cgacaatctg tgatgtcgga gtaacaagcg gaggataacc tgaatcctta cgaacacggg
    18721 gtacttctgc aagaacttcg tcaagcttgt cttccttacc ggcctgcttg agctgtgaaa
    18781 gaaggttgga aagcatacca ccgggaacct gatagataag agcgttagcg tctgttgcga
    18841 gcatcttagg atcaagaagt cctgacttga tgtacttctc acggagagtc atgaagtaag
    18901 cacggatgtc agagaactgt ttaaggtcaa gacctgtgtc gaactctgtg cctgaaagag
    18961 cggcaaccat tgactctgta ggtgcgtgtg atgtaccgag agcgagtggg ctgattgctg
    19021 tgtcaatgcc gtcggcacct gcctcaacac cctttaaaag acacattgat gcaagacctg
    19081 atgtgtagtg ggtgtggagc tgaagcggaa gctccggaac agcggctttg atagccttta
    19141 caaggctttc ggttcttgtc ggagtaagaa gagcagccat atccttgata cagattgaat
    19201 ctgcacctgc gtctgcaatt ctcttagcat actcaacata gtattcatct gtgaatacag
    19261 gacctgttgt gtagctgata gcaacctgtg catgaccgcc ttctttgtta gcggccttga
    19321 tagctgtttt aagattcttg atgtcgttaa gagcatcaaa aatacggata atgtcaatac
    19381 cgtttgcgat tgaacgctga acaaggtact caacgcagtc atcggcatag tgacgataac
    19441 cgagcatatt ctgtcctctg aaaagcatct ggagctttgt gttagggcaa tgctctctga
    19501 ttgtgcggag tctgtcccac ggatcttcgt ttaagaatct gaggcatgag tcatatgttg
    19561 caccgcccca gcattcgagt gagtaataac cgattttatc gagtttgtca agaacaggga
    19621 gcatttcctc tgttgtcatt cttgttgcaa tgagtgactg atgagcgtca cgcagagcag
    19681 tttcggtaac tctgattttt tttgccattt tacagcatcc ctttctccga attattgatt
    19741 agttaagtgt tacgagaacc ttacctgagt caacagactc accctttgca acatcaactg
    19801 ttgcaactgt gccgtcctgc ggagccttaa cgggagtttc catcttcata gcctcgatga
    19861 atacgaggtc atctccggcc ttaacagcct gtcctgccga aacaacaaca ttaacaactg
    19921 taccgggcat aggagccttt ataacaacag aaccctgagc gcctgcggga gctgccggct
    19981 ttgctgcagg agcgggagcg gctgccggag caggagcggc tgctgcggga gctgaagagc
    20041 caccgagttc ttcaacctga acatcatatg ctgtgccgtt aactgtaatt cttaaattct
    20101 tcatttttag tatccccttt tattttaaca agtaatcatt tatcagatag ttgaatgctt
    20161 ctttgaaagt gttgaaacac gcttgcccga gagcatatca agagcagaaa taagagtctg
    20221 acggagctga gcttcttcaa caataccgtc aacatagccg ttctgagcgg cattgtaagc
    20281 agaaagattc tcgtcagcaa acttctgagc aacctcagcc tgcttatctg tggcaacatt
    20341 cataacttcg ggagccataa tgaatgcggc agcctcaaca ttaacaggtg aaataactgc
    20401 atcgggaagt gcgtaaacaa catctgcatt agcgcctgtg ccagcaagag caacatagcc
    20461 tgaaccgatt gccttgcctg taacaacaga aatcttgact gttgttgcct cagcataagc
    20521 ggctgacgcc tttgttgccg acttgattga ctcaaagccc gggcagttta cgaatgttac
    20581 aacagggagt gagaaagcgt cgcagaaacg aacaaacttt gctaccttgt ttgcagactt
    20641 gcaaccaagc tccttgccct ttgtaacaac aatacctaca acctgaccgc cgagtcttgc
    20701 aaaacgaaca tttgcttcct taccgtaatc attgaagagc tttacaatac tgttgccatc
    20761 aactgttctg ctgactacac aaccgcaacc gtcctctgcc ggagcttctt caaatgactg
    20821 aggagccatt gtgaggttat ttgacggaag ataaaggata agttcctttg cagtcttgat
    20881 tgccttgtct gcatcgtcac aaacgattga ggcaataccg ttttcagcat tgtaagcagc
    20941 atcggaatgc ttgcctgtta ccgaaagtga aagctgtgcg tctttgctca taataacgat
    21001 gtctgcgctt gcggcgttaa gagcgtttgt tccgaggcaa gtgccgagaa caaccgaaat
    21061 ctgcggtaca acaccggaaa gtgacgcagc cgcattgaga acatcaccgc aacctgcgag
    21121 aagctctgta ccctgcttaa gtctgccgcc aacgctgtca tagaaaccta caacaggagc
    21181 gcctgtcttg agtgcaagac catacagctt tttaagcttg gcagcctgtg ccttactcat
    21241 ggcaccgccg caaatgtcgc tgttctgtgc aaacgcataa acaggcatac cttctactgt
    21301 tccaaagcct gcaacaacct cggcaaaacc ttcaccggat tttgcaaagg catcaatttc
    21361 acaaaagctg tctgcatcaa aaaacgccgt aattgtctta taagcggaag ttgcggcaat
    21421 ttcagccttt gcctgattga tcttttcaat actcatctta aaatcctcca ataccatgta
    21481 ttgaatatgc acgaaaacta agcgtgcata ctaattttct acacaataca ttatactcta
    21541 taatcttcaa aagtacaaga aaaacacgct gtactatttc aattttgaac acatttaata
    21601 gttattacac caaaaccgta aatttattgt cgaattaacg aatagtttta ttgaccgttt
    21661 cggaagtatt tttcaaaaac ggaaaattaa agctgtttgc cgtttaaaaa cgggtttgca
    21721 agcagttttt taacctcttg ttcggtcaaa tctctccagt cgccctgttt gagcataccc
    21781 atttttactc cgccgatctg ggtgcgtttg agtcttgcaa cctcaagccc gacagcctcg
    21841 cacattcttc tgatttcacg gttcttaccc tcgtgaagaa tcatttcaag aactactctg
    21901 ccctgctcct tgtgaattac acggacatat gcaggagcgg tttttctgcc gtcaagctca
    21961 acgcctgttt caagctttac aagctgatcc tcgtcaattg acggtcgaac ggttactctg
    22021 taaatcttgt aaacattgtt tttcgggtgc ataaccttgt ttgcaaagtc accgtcattt
    22081 gtaaaaacaa gcataccctc gctgtctttg tcaagtctgc ctatcggata aactcgctcg
    22141 ccgacattct caacaagctg tgcaacacac tttctgccac gctcatcatt cattgtggta
    22201 atgaatccac ggggcttgtt gagcataata tatcggtaat taccgccctt cggcacaaca
    22261 atcctcttgc ctcttacaaa caccttgtct gtaggaagaa ccttatcgcc gagaattgcg
    22321 gttttgccgt tcaccttgac atgaccgccg agaataagct cctcggcctt tcgccttgac
    22381 gcaataccgc attgcgctat gaatttctga agtcttatag gttcaatttt agccatatgt
    22441 aaattccttt ttattaaaat tttctgtata tttaagctgt cacgaaaaca gatttcctat
    22501 tgccgaaaat attgacacac tttttttatc cgatttaatc ttttcgcctg caacaatgct
    22561 gcatttataa agcagctttc cgccgagtgt gtattcaatt ctgccaaccg attcgttctt
    22621 ttcaatcgga gcatacaaaa agctgtctat gaagattttt ttcttgattt tatcgcagtc
    22681 ctcacgcttt aaaacgattg tgttgttctt ctcacctgta accgttacgc tgtccttatc
    22741 accgcccacg cacggaatat cggcacaaaa gtcagcgtcc ttgcagtcaa ctcccctgta
    22801 cttttcaaaa gcgtaatcat aaagagaaat atggtcattc caatcgttgc ggtcattcag
    22861 cgtgacgcac acgagcgtta caccgtcttt ttttgcagag gaaacaaggc accgccctgc
    22921 caccgttgta tagcctgttt ttccgcctgt acagtaggga taaagcgaca aaagcctgtt
    22981 atgatttgca tatgcggttt tctttgattt cggttcaaga aattcaacgg tcacgctctt
    23041 cttagccgta agatttgcaa aatcgtcatt ttcaagtgca tatgacataa gcagagccat
    23101 atcctttgca cttgagtaat ggttatcatc gtcaagtccg ctcggcgtta caaaattggt
    23161 attcgtcata ccgatttgct ttgccttttc attcattcgt tgtgaaaact tttcgggact
    23221 gcccgaaa
//
