LOCUS       gnlProkkaBMLIJEHL_75   12912 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMLIJEHL_75.
ACCESSION   gnlProkkaBMLIJEHL_75
VERSION     gnlProkkaBMLIJEHL_75
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 08:58:19
            Original ID  :: gnl|Prokka|BMLIJEHL_75
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12912
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12912
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9583:12265]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9584..12265
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..12912
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12912
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             115..1083
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_1"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
     CDS             1278..3959
                     /locus_tag="ctg75_2"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPDGEIGTEYQVQLEADTDVNWSLEEGSELPAGFTLSSGGVISGMPQEEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIA
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKVKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVTVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKSVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             4246..5010
                     /locus_tag="ctg75_3"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILTAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTSGGKENSNQTADKKTKVFASSNNAGDVQNSGNDADNTDD
                     SQNTDDSQNTYVDNNSSENNGSTGDGGNQIDQTADQAMIYDSEGNGRLISQADDGNWYD
                     SDGNCYGSWEDIGRAMDEDGVTDQDGNKYYWTWTAPDDASGKVRDPYDLYSWDPGTNSY
                     IPFQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5153..6040)
                     /locus_tag="ctg75_4"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGAYNTKSMKSVFLSCGFKDVTSSVNLDNGSGMKRGDVLLNIARHTVMHIGNG
                     KVVSASINENGGAHGGTPGDQNGNEIKIQNYYNCPWDCVLRYNEDSTSTDPEPQPTTGN
                     AKIRKGQSYANKFANTGISITGKRDAATKKAAIKVLQTALNKDYGAGLDVDGIWGTNTS
                     NALGKHYVKSGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGLTV
                     SGTCDRNTFLKLIS"
     CDS             complement(6228..6563)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg75_5"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             6682..7236
                     /locus_tag="ctg75_6"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7242..8054
                     /locus_tag="ctg75_7"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGGMKNAESFIVWTGNVYGDRDRCLDIWTDVSEKKYGN"
     CDS             8026..9423
                     /locus_tag="ctg75_8"
                     /transl_table=11
                     /translation="MFPKRSMETEKDKTVWKIILIILLYFTAYSFCGSYLENNIETKKT
                     ILIILLVLVGICLIPDCVVRLKRIRNFQSVLFFVMIVVLVTCQYWTAYISGNVIVFGNL
                     YLPIFLTIFFRCTFIQSYIWEFLYLTNIGLLKLLYIITVCVIKKRKIGEYIYFQNMHSY
                     SSGIYLLVISVVIILLLKLFRVNKYAGDIFRGNQKFFYGFALVEYILLYFLLSIQNKIL
                     KIENLVITIVVVSGIAVVLMILFMFFFVKSVNIEKNILEVKNRAVEQQYQELEDAYQKY
                     RCIIHDQKHMLSFIQECIENKDLNGIAAYVADNQKKFRDEEKKFWTGIDVLDKTITMKK
                     RKMDALDINFELDASVDDTIINTTDLVIILSNLFDNAIDAAVKSKEKKICLRIKNINDV
                     LMMKMWNTSTRIPDVKRGKFVTDKLEAEGHGWGIESVKRLVKRYDGNITFKYDSDFFQV
                     IIILSKS"
     CDS             9439..9567
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNGSFFSICC"
     CDS_motif       9439..9543
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /locus_tag="ctg75_9_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9544..9567
                     /prepeptide="core"
                     /locus_tag="ctg75_9_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="769.9"
                     /monoisotopic_mass="769.3"
                     /core_sequence="SFFSICC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /leader_location="[9438:9543](+)"
     CDS             9584..12265
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     765.3; E-value: 1.6e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_10"
                     /sec_met_domain="DUF4135 (E-value: 6.1e-94, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.3e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFNHYNNAISERIFILSIHEQKAKGNLKGNTSEEQYDYYEKKY
                     LNNATYIKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKFSGT
                     VGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISCRTV
                     QYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHGEYP
                     VIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNRGVLI
                     SAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTECII
                     RGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRECRKA
                     LLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPCTPY
                     ESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYSQIR
                     KIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHDFEE
                     KNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTGKRV
                     WMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEKDLW
                     KKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLLRYED
                     SLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADS
                     LFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGT
                     EYLNLAFMNGISGTGMALMEIL"
     CDS             complement(12318..12842)
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
ORIGIN
        1 ccgctatgac gcccttattc gaacaaaatc tcccacaaat tgtgacgcac atcttgcaga
       61 aagccttttt cagacacgct ctggagtagc gaagaaatat gggaggacaa taaaatgaag
      121 ttaggtattc tgggagcagg aggcattgct tctactatgg cgaaaacagt ggcaggaatg
      181 aaagatgtgg aggcgtatgc ggttgctgct cgtgatctgg aacgtgcccg ggtatttgca
      241 cagaaatatg aagtaaaaaa agcatatgga tcctatgagg aaatgctggc agatgatgag
      301 gttggactgg tttatatcgc aactcctcat tcacaccatt atctgcatgc gaaaatgtgt
      361 ctggaagcgg gaaagcatgt gctttgtgaa aaggcattta ctgtaaatgc agagcaggca
      421 caaaaattat ttgaccttgc aaaagagaaa aagcttctga tcacagaagc aatctggaca
      481 agatatatgc cgtccagaaa gatgatcaac gatattattg aaagtggtgt gatcggagaa
      541 gttacggcag ttaccgcgaa tctcagctat acagtaagtc atgtggaacg tatccgtaaa
      601 ccggagcttg caggaggtgc tcttctggat gtaggcgtat atccgatcaa ttttgcctcc
      661 atggtgcttg gcgataaggt aaaggatgta aaggctactg caatctttca gaatggagtg
      721 gatattctgg acagcattgc catggtgttt gagggagacc gcatggcaac ccttcagtgt
      781 ggagcaagag aaatctcaga cagaatggga agtattttcg gaaccagagg atatatgcag
      841 gtgcagaata tcaataatcc ggaaaagatt acagtgtttg ataccgaaca taaagaagtg
      901 gcttcttatg ttgtgccgga acagatctca ggatatgaat atgaggtaga atcctgcatg
      961 aaagcaattc atgagggaaa aacggagtgt ccggaaatgc ctcatgcgga aacaataagg
     1021 atcatgaaaa tcatggacga catccgtaaa tcctggaatt atgagattcc ctgtatcgaa
     1081 taaaaagtgt ggaataatct tataaaaaag accagtaatg tttttgacat atacccgaaa
     1141 cattactggc ttttctgata ttcatgacca ttatacaaca tgtcattccg taattacaga
     1201 aacattcccg tccagtggta tattaatatt aattaggtaa attgatactt ttatatttta
     1261 ttatctggag gagaagaatg aaaagtaatt acaaaatttt tacagcagtt tttttatcgg
     1321 caattatgac agcagcagct ccgttaacag tatgtggggc ggaagttttt tcggcgggag
     1381 aatctttcag tgatggaacg gggagtattc ctgccatatt gacagatatg gttctgccgg
     1441 atggagagat tggaacggaa tatcaggtac agcttgaagc tgatacagat gtgaactgga
     1501 gtctggaaga gggaagtgag cttccggcgg gatttacgtt gtcttccggg ggagtgatca
     1561 gtggaatgcc acaggaggaa gggagtttca gctttactgt acaggcggac aatggtattg
     1621 gagtttcttc acaggaactg agcctttatg ttgcacagcg tgagcaggaa cctgttataa
     1681 agcagtatga gctgacatca ggtactgctt tgatcgatct gggaattcat gcagagggag
     1741 aacagtcacg taagcggtta tttctttata atgcaggaac agattcgctt catctctctg
     1801 attttccgca gagcagatat tttgattttt cctacgcacc gattttcgat acaaatacgg
     1861 atgaagaaat gcagcccgga agttgtgcgg ctgtggacat tgatgataag aagaatctgc
     1921 ctgccggaaa ttatgaagag acagtgacat ttgagacaaa agagggtgct tcctgtaagg
     1981 ttactctgaa agtaattgtg ggagcttcct ctgaaaaaga ttatgagctg agtatagaaa
     2041 caggtacaga agaagaattt acagaaagcg atttctatga cccggaattt cgtgtggaga
     2101 agtatgtagt ggtcagaaat tcaggaaaaa aggaaaccag aatacggata gatacttctg
     2161 gtcttaagaa ttttgaagtg gatgaccaga tggcaaagtg gacagaagat tatgaggaac
     2221 aggattccaa aaagctgctg aaaccgggag aaacgcttta tttttatata ttgccgaagc
     2281 aggaatacgg aatttatgat gaaacgtttg catttctcgc agatgacgga agcagatatc
     2341 ctcttcatgt tacaatgaac agagagaaga atccgacaga aaagaagcag ctggaaatta
     2401 ctgaaaagtc tgccgggggt tttccgacaa tgcagtgggg ctataagaca cttccggaag
     2461 caaagacata tattctgaaa aatgttactg atacagatat gaagctgtct tttaaccgta
     2521 gtaaagaatg tagtgtgtta ttatctggaa atgcttatct ggcacctggg gagagcacag
     2581 aactgagact ctggcccaaa ctggggcttt cggtgggaaa atatagtttt caggtgactg
     2641 tgactgcgaa aacagtggca ggagaacacc tgacaacgca gaatctgtat aattctttta
     2701 ttgtaggaga ccggacttat cagggactgg cagatgctgt tgcgcctgtg accggaatta
     2761 ccaatggtgc agaaaaaact gctgatgctt tgcatctgcc gaagtcgctg gaagtctatg
     2821 gcgccgaggt gaatggagag aaaacaacat tttctgcgtc tgtgaagtgg gatgtggaga
     2881 attgtgctta tgatccgaaa agcaaggcag ctcaaagttt tctggtcaac ggatctctgg
     2941 aactgaatga ggatgaaaat aatgaagggc tggacactgc cgtacagata atggtacagg
     3001 tggatgctta tcagacatta aacagaccag ttattgatac gcggtggacc agagtgatca
     3061 caaattatgc aatgctttat ctgagagatc tttccaatga agcggacggc tatcagtttg
     3121 tgacagcgaa atctcagaag gatctgaaaa aagggaatta tactgcgcag acaaaaattg
     3181 caaattctga actgaatcaa tatcctgagc tgaagtatat tccggaggga acacatagtc
     3241 tttattgcag ggcatacaaa gagaacagca gccatgttat ggaatatggg gaatggtcag
     3301 acggggttcc ggttacggta aaggtaaaga ctccggacgc acctgtggtt cagaaggtgc
     3361 aggtgaagaa aaatgatgtc agaatagtac ttaacagcaa gggtgaggaa ccggacggtt
     3421 acgatgttgt tgctgccaga agtaagaacg gaaaagaacc atcggattat ataaaggtaa
     3481 agagtgggta ttccggaagc agtaaagagc ttatcttacg gggtgtaccg gcaggaacgt
     3541 ggtatattgg cgtacatgct tataaatatc tgaatgggag caataccaaa gtgctcagta
     3601 aatgggcaga ggtcaggaag gtaactgtaa aaacaagcct tgtaacagga aaacctgctg
     3661 ttaaatcagc taaggtttcc agacagggaa caaaaagaaa tgtaacggtg acgtttactg
     3721 ttccaaagtc ctgtgatgga acagactggg tactggcaaa gaaagtttcc aaatctgata
     3781 atggcagcta tactggtgta agcagttatg cttacacaaa gaaaaatcag acaaaaacca
     3841 cggtggtctt taaaagtgtg aagcccggag tctactacct tgcaggacgt gcctatgtaa
     3901 aaggctatgc aaaaagttat acgaaatggt cgaaaataaa gaaaatagtt gtgaaataag
     3961 cactgttgcc atttgtttca cagagatttc acttttaaga aaaaagctcc cgcttttacc
     4021 aggcgtttat acatgctttt tcccgtaata ctcaaaattt acggtactgc caataaactt
     4081 attatactca aatcttgtct gaatttggag ataaataatg tcctttttat gacagataag
     4141 ggacatatga ggcatcaaag cctgtggagt atgtaataat gaacaggaaa agcacattat
     4201 gataaaggca atgacatttt tagaaaatgt agaaaggaca acaaaatgaa gcagaaaaag
     4261 attgtaatta ttatggcagg gattttaaca gcagcggctg ctatgacggg ctgtgcggaa
     4321 cagaataaaa cagcgacaca ggttgattat acgcagaatt cacaggggaa atccgaacag
     4381 acaaaacaaa aaacagcaga aaaatctcag ccggataaaa aacaggtaaa taaaagtaca
     4441 tccggtggaa aagaaaattc aaatcagact gcggataaga agacgaaagt atttgcctca
     4501 tccaataatg cgggcgatgt acagaattca gggaatgatg cggataatac agatgattca
     4561 cagaatacag atgattcaca gaatacatac gtggacaata attcatctga aaataatggc
     4621 tcaacaggcg acggtggcaa tcaaattgat cagacagcag atcaggcgat gatatatgac
     4681 agtgagggaa atggaagact gatttctcag gctgacgatg gaaactggta tgacagtgac
     4741 ggaaattgtt atggaagctg ggaggatatt gggcgtgcta tggatgaaga tggtgttacg
     4801 gatcaggatg gcaataaata ctactggacc tggaccgcac ctgatgatgc atcaggaaaa
     4861 gtaagagatc cgtatgacct gtattcctgg gatccgggaa ccaattccta tataccgttt
     4921 caggctgcgg aatctgactg tagtcctata ggcagaggaa acggctggta ttattatgat
     4981 gaagacagcg gcgaatatgt tccgtggtaa aaaataagaa aacaaaagaa acagttttga
     5041 aatcattttg atgggtttca aaactgtttc tttttatata caagaaatag tgaaggggca
     5101 tatccggcag aatcagtgaa aagaattctg ccggatgttt atctggtaaa gatcagctga
     5161 tcagtttcag gaaagtattt ctgtcacagg ttccggaaac cgttaagccc tgtgccttct
     5221 ggaatgcctt tacagcagag agaagtcctg agccaaaggt accgggaatc tctacaccgt
     5281 ttggatcata agcacgtaaa agaaggagaa tctcagcggc agttaccata tactgggttt
     5341 caccgctttt tacgtaatgt ttaccaaggg cattgcttgt gttagttccc cagataccgt
     5401 ctacatccag accggcacca taatctttgt tcagagctgt ctgaagaact ttaatagctg
     5461 ctttcttagt ggcagcatct cttttcccgg taatggagat gccagtattg gcaaatttat
     5521 tggcataact ctgacctttg cggattttgg catttccagt agttggctgt ggttctggat
     5581 ccgtagatgt agaatcttca ttataacgaa gaacacaatc ccacgggcag ttgtagtaat
     5641 tctggatttt aatttcgttg ccattctggt cacccggagt accaccgtgg gctccaccat
     5701 tttcatttat actggcagaa actactttgc cgttgccgat atgcataact gtatggcgtg
     5761 caatgtttaa cagtacatca ccgcgtttca taccgcttcc gttgtcaaga ttaacactgg
     5821 aagtaacgtc tttgaatccg caagacagga aaacagactt catacttttg gtattataag
     5881 ctccttttgt ttttacaggt acaccagcct gctgccatgc agagattacc agtgaagaac
     5941 aatcgtagtc cggtccccat ctgttatcct gatcatatcc gtgtgccgga tcgtttgcga
     6001 tttcaattgc ccatgttact gctttttctg tttttgtcat ttttttatcc tcctgaaatt
     6061 tgattattta tttgctcacc ggtgatacat cttataaaga gtgagaaaag ggaaaaatgt
     6121 aaacatgaaa cagaaaaaaa taaaaagcat ttcctgattg ttgcttcgag gtcagaaaaa
     6181 tgcttttcga ggacaaaaac acgaaaattg tcgaattgta attatattta atcctgatga
     6241 gaggcctgat atattttcag tatttttaca atgtattcag tctggcgttc acccatttga
     6301 ttcatgattg aaatcgcatc ctgaatagcc gggctttgaa tatctttatt atgaggaagc
     6361 agatcataaa gaaaatagtc aagtcccaca tcaagaattt cagaaagctt aaggagattt
     6421 tcgatagtag gcatatactt acctgtttca atccggctga tcgtacttac agataaacca
     6481 cttaattctt ccaggtgttc ctgggtaata tttctgttga tccgagcttc tgcaattctt
     6541 tttccgatag tattgttttt cataaataaa aatcctttcc tttgataaag tttaacagac
     6601 ggaattaaat atgtataagg atataaatga caagcgacta atcaaatttg atatgtttta
     6661 tgacaggagg aatataggaa tatggacgaa tatacaaagg atttgtatac catgatgttt
     6721 tctttgcaga ctttgcaaaa tcagggaatt acaatcagag aaactgtata taaaagtctg
     6781 gacaaattac tgttatggaa taaagaatct gaaaacagta aatatctcga attagcgttg
     6841 cttcatatgc aggcttatgc taatatggga tttgctttag atgaagaaaa taagacaata
     6901 cgtgagatat taaaaaagac aggaaagacc agagaagact ttttcccgaa aggatatctt
     6961 cttggaaaga gaattaaact gaccaagtca caggttcgtg gtatgattgg aagatggaga
     7021 ccttccagag acagtccgat gacaatcgga gaactggtgg atgatatcat cagaaaggta
     7081 aaaaaccatg aggaaggcag atacatttat cagtatcaca gaactgatgt gacaaccaaa
     7141 ggggatatcg aggtttatga gctggtcatc aataaggatg aaagttattt ttatgatgtg
     7201 aagaaattca gattttatac attcatggag gaataattgc tatgataaga ataatgattc
     7261 tggatgatga cgaaatgtat ctgaaaaaag aaaaggatat cacagaacag tattttgcag
     7321 agaaaaacgt agattgcacg gtaacgatat accagaatgt ggaatggttt ctgctgggat
     7381 tgaatgaaga aaaattcgat atgtatattc tggatatccg gatgcctgga gaaaacggaa
     7441 tagaggcagc gagggaaatt cgcagacttt atccggatcc ggttattata tttattacaa
     7501 attttgtgga ttatgcaata gaagcatatg aggtaaacac ctatcgttat atccccaaag
     7561 agtgtctgaa ggaaaaactt ccgcaggctt atgatgcgct tcttcctgga attatggaga
     7621 aagaagagcg gtactatatc ataaataaaa gaaatgaagt tgaaaaactg gcatattctg
     7681 atattttcta tatgaaaaaa gaaggaaaat atgtcatttt tgtgcacagg cgtggggaag
     7741 taaagatcag agcaagtctg tcaacagtag aaaaggaact gaattcaaaa gaatttatta
     7801 tatctgacag aggatatctt gcaaacatcc aacatgtgat gaagatgaaa ggaagggatc
     7861 tttatatgcg ggacggtaat attattacag ttggcagaga aagattcaaa ggtgtcagag
     7921 aagcaattct gaattactgg gggggtatga agaatgctga aagttttatt gtatggactg
     7981 gcaacgttta tggagacagg gataggtgtc tggatatttg gacagatgtt tccgaaaaga
     8041 agtatggaaa ctgaaaaaga taaaacggta tggaagataa tattaattat actgttatat
     8101 tttacagcat attcattttg cggatcatat ttagaaaata atatagagac aaaaaaaaca
     8161 atacttatta tattactggt gctggtggga atatgtttaa taccggattg tgtagttagg
     8221 ttaaaaagaa taagaaattt tcaaagtgtg cttttttttg ttatgattgt tgttcttgtg
     8281 acctgtcaat attggacagc gtatatatct ggaaatgtaa tagtatttgg aaatctatat
     8341 cttccgatat ttttgacaat tttttttcgg tgcacattta ttcaatctta tatttgggaa
     8401 tttttatatt tgactaatat agggctatta aaattattat atattatcac agtttgcgtg
     8461 attaaaaaaa gaaaaatagg agaatatatt tatttccaaa atatgcactc ttatagctca
     8521 ggaatttatt tgctggttat aagcgttgtg ataattttgt tattaaaatt gtttcgcgta
     8581 aataaatatg ctggtgacat ttttagaggt aatcaaaaat ttttctatgg ttttgcatta
     8641 gtcgaatata tacttttgta ttttttgcta agcatacaaa ataaaatcct taaaatagag
     8701 aatctggtaa ttactatagt agtagtatca ggaattgccg tagtattgat gattttattt
     8761 atgttttttt ttgttaaaag tgttaatata gaaaaaaata ttttggaggt gaaaaataga
     8821 gctgtagagc agcaatatca ggaattagaa gatgcatatc aaaaatatag atgtattata
     8881 catgatcaaa agcatatgtt aagttttata caggagtgta tagaaaacaa agacttaaat
     8941 ggaattgcgg catatgttgc agataatcag aaaaagttca gagatgaaga aaaaaagttt
     9001 tggacaggta tagatgtact tgacaaaaca attactatga aaaaaagaaa aatggatgct
     9061 ttggatataa attttgaatt agatgcttcg gtggatgata cgattataaa tactactgat
     9121 ttggttatta tattaagcaa tttatttgat aatgcaatag atgcggctgt taagagtaag
     9181 gaaaagaaga tttgtttaag aataaagaat ataaatgatg tattgatgat gaaaatgtgg
     9241 aatacaagta cgagaattcc tgatgtaaaa cgcggaaaat ttgtaacaga taaattagaa
     9301 gcggaaggtc atggatgggg aattgaaagt gtaaaaagac ttgtaaaaag atatgatgga
     9361 aatatcacat ttaaatatga ttctgatttt tttcaggtaa ttattatttt aagtaaaagt
     9421 taaaggagag ataaaaaaat gacagaagaa tttattggat gtattgagga agaacttaag
     9481 gaaatagaac tgttttatga agaaaatgga gtagaagtgg aagcatatac tttacataac
     9541 ggatcttttt tttcaatatg ttgttaaagg aaatagaaaa ggtatgccag actttaatca
     9601 ttataataat gcgatatcag aacggatttt tatattgagt attcatgaac aaaaggcgaa
     9661 aggcaatcta aaaggaaata cttctgaaga acaatatgat tattatgaaa aaaaatatct
     9721 taacaatgca acatatataa aatctttact gcaggaatat cccgagttaa aacgtctgct
     9781 tgaattgaaa aataactcta tccagagagc agaatgtgaa atcaggaaat ctctttatgc
     9841 agaaaaagaa cagatacaaa aaatattctg tgatggaaga aagttttccg ggactgtggg
     9901 aatttacatg tcgaaaggcg atatacacag aggaggacga agtgtggcga aggtagaatt
     9961 ggataatgga acaattctgt actataagcc acatagtctt gataagaata taaaatatca
    10021 ggaactttat aactatttat gcagaaaaac aggaatttcc tgcaggacgg tacaatattt
    10081 atctcatgat tcctatggat gggaagaaaa aattgagaat attccctgta aaaacgaaag
    10141 tgaggtggag cattattatt tcagaatggg catacatctg tttttgggat atgccctcgg
    10201 agcaacagat cttcatggtg aaaatattat tgcacatgga gaatatcctg tgattatcga
    10261 tatggagaca tatccgggat atttaaaaca acaatcagag aaagacggaa gtagtgtaga
    10321 agaaaaaata aacaaaagta cagagataaa attggcaaat tcggttatac atacaggaat
    10381 gcttcctgtt ctcacatggg gcagaggaaa cagaggagtt cttataagtg caatgggaac
    10441 agaggaaaag ataaaaacac cgtttaaact tcctgtggta aaggatgata aaacatctga
    10501 tatccacata gaatatgaac ctgtggaaat gcagataaag gaatgcattg taagactaaa
    10561 tgatcaggtt atcaatgcgg cagattatac ggaatgcatt atcagaggat tttgcagagc
    10621 gtacatggtg gcaatggcag ataagaaagt ggaggtgatg ttgtccggct tttttgacgg
    10681 acgttccaga gttgtactgc ggcataccca acagtatgca atgtatctta tggcttcgtt
    10741 tcatccggat tatatgaagt caagagaatg caggaaagct cttttgaatg tgattcacaa
    10801 agagggggaa tcttctttta tgaaagagat tcatgattat gaaattgaca gccttctgga
    10861 aatggatata ccctgctttg agattgatgc gaacagcaga tctgtttatg atggaaatgg
    10921 cggagaacat aaagaatatc tgccctgtac tccttatgag tcatggcgaa tgcatatgaa
    10981 gcagatgagt tactctgata tggaatgtca gtgtgattat atcaggctgt ccatggaaat
    11041 gctgaaggca tctgatggaa agaaaaagat gtttccgacc aggataaagg gatatgacac
    11101 agataaagag cgcaaaatat acagtcagat cagaaagata gttcatcgaa tctgcagcag
    11161 agcaattatc cgggaacaga gcgccggctg ggcgggtctg caattctggg ataatggtca
    11221 ctggaatctc agatcaggtg gaatatattt atatgatgga atatccggga tagtcttgtt
    11281 tcttgcaaaa tatcttcatg attttgaaga aaagaatgca agtgcagaag aaatttatca
    11341 tcttgctgtt ttgagattga aagcttatac agatgaaata cacaaaaaac agatttatga
    11401 taaaaatctt ctgacaggta ttgtaaatgg agaaagctcg gtggtatata cctatcttta
    11461 tctgtttaaa cttacaggaa aaagagtgtg gatgatttat gcggaaaagc atttcagcat
    11521 tattgagagg gtatggaaag aagattcaca actggattat ctgagcggaa atgccggagc
    11581 tattgtagtg gcagtgatgt tatataaaga aaccggaaat ctgaaatatt atgaaatagc
    11641 ggcagatatg gaaaaagatt tgtggaagaa aggacaggaa accggaaatg gatacggatg
    11701 gagattaaaa ggaacagacg gaccgctggc tggaatgtct catggcaaca gtggatttct
    11761 gatggcttat gcagcgttgt atgaatgtaa tcataaagcg gaatatgctg ataaaataca
    11821 gcttttgctg agatatgagg attctctgta ctcagagaaa gccggaaact ggaaggattt
    11881 acgagagagt tcaggggaaa gcttcatgaa tgcatggtgc catggggcgc cgggaatcct
    11941 gctttcacga atgaaactgg aagagctgtt tcctgaggat atgcagatta aaaaagacag
    12001 gttaaatgct gcagactctt tgttttatgg agaacaggat gaaaaaattt gtctgtgtca
    12061 tgggatgtcc gggaatttac ttattatgaa gaagtacctt cgaaaatatg gtaataaaaa
    12121 aatgaaggag caatatgagg cgttatgtga ctgcctttta tttcaactgg atcacccggc
    12181 aaaaatatct gggacagaat atctgaatct ggcttttatg aatggcattt ccggtacggg
    12241 aatggcatta atggaaattt tatgaaaact aagggaacac ctgcagactg taaatttatg
    12301 gtcagcaggt gtttctttta tttgttttcg gaaatatatc tgagaattag tttcttcttc
    12361 atccgattga cgtactggcg ggacagcttc agtttccggg caatctgggc atcgctttta
    12421 tcctgataaa agtacatgga cagaattttt ctctggacac tgtccgaagg gtaagagttg
    12481 atatatgcgg ttacatcata ataggtgtca tcaaaactgt cgggagcctg taatgaaaca
    12541 gaacaagaat caaaatcatc tttttcaggt tcggaaagac aactgcggca aagggaacga
    12601 tatctgtttt cgacagaggt ctgcatgtat ctgatacatt caccttctga ggatgaagaa
    12661 cttaaatatg gcaatgtctt taacaaagta agatacaatt cctgtgtgga atcttcgcgt
    12721 tccatgcagt gaatccggga tgcatatcct ttcacaagcg gttccatacg tttgagaatt
    12781 tcactgtctg aatctgggat accattttga taattttgga taagttctgt cagtgttttc
    12841 ataggtatct acctcctttt taggggaagt agtaagaaaa ctgctgatca gaaactaaaa
    12901 aagaaaaaaa tt
//
