LOCUS       c00001_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMLIJEHL_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 01:02:09
            Original ID  :: gnl|Prokka|BMLIJEHL_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 46194
            Orig. end    :: 69443
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[56194:59443]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1387..2844
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_48"
                     /sec_met_domain="FGGY_C (E-value: 6.4e-38, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 3e-79, bitscore: 258.1,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFIQSMEGMKELTKDIDRTQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSEAVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(2955..3890)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_49"
                     /sec_met_domain="LysR_substrate (E-value: 3.3e-33,
                     bitscore: 106.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAIEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4006..5430
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_50"
                     /sec_met_domain="Lyase_1 (E-value: 1.6e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 5.9e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5539..7224)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_51"
                     /sec_met_domain="FTHFS (E-value: 2.9e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_52"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.7e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.7e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_53"
                     /sec_met_domain="Spermine_synth (E-value: 2.1e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.1e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_54"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.6e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3e-35, bitscore:
                     113.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWDYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_55"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.3e-14,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_56"
                     /sec_met_domain="PAD_porph (E-value: 3e-128, bitscore:
                     419.6, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSQAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_57"
                     /sec_met_domain="CN_hydrolase (E-value: 1.8e-55, bitscore:
                     180.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTVEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15591..16052
                     /locus_tag="ctg1_58"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNNQ"
     CDS             16274..20983
                     /locus_tag="ctg1_59"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYDTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAATASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGEMITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARLVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDEKSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQSITQLTAGT
                     EDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSLKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLIQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDRRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTVTPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20980..21867
                     /locus_tag="ctg1_60"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSHLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22059..23150
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     106; E-value: 8.9e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_61"
                     /sec_met_domain="Peripla_BP_3 (E-value: 9.6e-33, bitscore:
                     106.0, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIVYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 actctgatcg cagagagatt tgacggacct tgtatgtatg tagcagcagc agaaggtgac
       61 ggtgatatga tcaacggcag aggtgatgct tactgtggta tgcttaactg ctcctacaac
      121 ttaaaaatgc gtcatctgaa agcatatatt ccggaatatc ctgttggaac agcagatgat
      181 attgcaaaga tgatcgctga tttcgtaccg gttgcacgtg cagtcatcgg tgtcagcaat
      241 cttaagatca ttactttcgg accacgtcca caggacttct tcgcatgcaa cgcacctatt
      301 aaaggcctct atgagctggg tgttgagatt gaagagaact cagagcttga tcttcttgtt
      361 tctttcaaag agcatgaaaa tgatcctcgt atcccggaag tttgtgcaga tatggcaaaa
      421 gagatgggcg aaggcaaata ttatgctgac cttaatgtga aaatggcaca gtttgagctt
      481 acacttcttg actgggcaga ggctcataag ggagcaagaa aatacgttgc atttgctgac
      541 aaatgttggc ctgcattccc gtcacagttt ggatttgaac cttgctatgt aaatagccgt
      601 ctggtttcca gaggaattcc ggtatcctgt gaggttgata tctacggagc actcagcgag
      661 tacatcggac tttgcatttc caatgatgca gttacactgc ttgatatcaa caactctgtt
      721 ccacagtata tctatgatga agatattaaa ggaaaatacg attataagct tactgataca
      781 tttatgggat tccattgtgg aaatactcct gcatgcaaga tgtgtgattc cagagctgtt
      841 aaatatcagc tgatccagca cagacttctt gagccggcag gatctgaacc agacttcaca
      901 agaggaactc ttgaaggtga tatcgctgca tctgacatta cattctatcg tttacagtgc
      961 aattccgagg gcgagctggt ttcttatgtt gcagaaggtg aagtactgga tgtacctaca
     1021 agatcattcg gtggtatcgg tattttcgca atcaaagaaa tgggaagatt ctaccgtcac
     1081 gtactgatcg agggcaacta tccgcatcat ggagcagtta tgtttggaca ttacggaaaa
     1141 gcattctatg aggtagtgaa attccttgga ctggatgtta agaagattgg atacaaccag
     1201 ccggcaggtg taagatatcc gacagagaat ccatggggtt aatgagaaat cagtaaaacg
     1261 ggttattaat gttcatgtga tgtaaatgaa tctgaataca gaataaataa actgacacta
     1321 tattaaaggc atcccggggc tttgctctgg gatgtattag attagaaata gaaaaggagc
     1381 acacttatgt attatatcgg tattgatctt ggtacttccg ctgtaaaact tcttcttatg
     1441 gaagaatcag gaaaaatctg taacatcgta tccagagaat atccattatt cttcccacat
     1501 ccgggctggt ctgagcagaa accggaggac tggttcatac agagcatgga aggcatgaaa
     1561 gaactgacaa aggatattga cagaactcaa gtagcaggaa ttggttttgg cggccagatg
     1621 catggtcttg taacacttga taaggatgat aatgtgatcc gtcctgcaat cctctggaat
     1681 gacggacgta caggcgaaga gacagaatat ctgaatacag tgatcggaaa agacaaactt
     1741 tcacagtata cagcaaatat tgctttcgca ggcttcacag caccgaagat cctctggatg
     1801 cagaaaaatg agcctgagaa ctttaagaag gtagtaaaga ttatgcttcc taaggattat
     1861 ctggcatatc gtctgtccgg ttctttttgt acagatgttt ctgatgcttc cggtatgctt
     1921 cttcttgatg tgaagaaccg ctgctggtca aaagaaatgc tggagatctg tggaatcaca
     1981 gaagagcagc ttccgaaact gtatgagagt tgggaagtag taggaactct gaaacctgag
     2041 attgcgaaag agcttggatt cagtgaagct gtaaaggttg ttgcaggtgc aggtgacaat
     2101 gcggcagctg ctgtaggaac aggtacagtt ggtgacggtc agtgtaatat ttctcttgga
     2161 acatccggaa ctgtgtttat ttccagtaag aactttggcg tggacgaaaa taacgcactt
     2221 cattctttct gtcatgcaga tggaagctat catctgatgg gatgcatgct cagcgcagct
     2281 tcctgtaaca aatggtgggc agaggagatt cttcagacaa aggatttcgc ggcagagcag
     2341 gctccaattc agaagctggg agagaatcat gtattcttcc ttccatattt gatgggagaa
     2401 cgttcacctc ataataatcc tgatgcaaga ggtgtattct tcggaatgtc catggacagc
     2461 acaagagcag acatgacaca ggctgttctg gaaggtgttg cctttggtct tcgtgattcc
     2521 ctggaagttg caagaagcct tggaatcaag attgagagaa ccaagatctg cggtggcgga
     2581 gctaagagcc cactgtggaa gaagattatt gcaaacgtta tgaacctgaa ggttgatgtt
     2641 ctggagaacg aagaaggacc gtccatgggt ggagctatgc tggcagcagt aggctgtggt
     2701 gcttacccgg atgtagaaac catcggtaag aaatttgcca aagttgttga tacagtagaa
     2761 ccggatcctg aactggttgc aaaatatgaa gagagatatc agaagttcag aactctgtat
     2821 ccggcgatga agccattgtt ctaatcgaat atctgcctga catactgggg ttgttgtgct
     2881 tatttagcac aacaacccca ttttgacgta catctgatga tgaccaatca ccatagccta
     2941 ttgattatga catatcagga aaagggcagc ttcaggaatt cttccatggc tctgctgata
     3001 tagcggcctt tcttccagta aaaaaacaca gtgcgtttac tgctctgacc gggcagctta
     3061 taaaaaacaa gttctgaatt tgttggaact ctggagagca gaagatcccc gatgaaagtg
     3121 atacccattc ccaaacatgc aatattatag gcagtcatct gctgatccag gcgaaatact
     3181 acagaaggcg aaaagtgatt ttcctgacaa atggtaagtg cacgcttacc ggtatcatta
     3241 tctgaacgaa gaataataaa tggttcgttc tcgaatttgt ttaatggaac agaaggaata
     3301 tgagaagaac ggaactgccc gttccggatt tcctcaatag gaatctgata ttcctgcagt
     3361 ctggtattta ctgaataatt tttgggaacc gctagaagaa gttgttcttt ctggtagata
     3421 taatgttcaa aaatctggtt atccagaata cagttatcaa tcaccagatc taactttccg
     3481 gcctggagaa actgggatag ctttgctgta ctttcttcta caagagaaat ttgaacatgg
     3541 gggaattttt gggaaaaatc agcaataagg ggaggcagaa tccacgaaga aaaaaagtta
     3601 ctgccaccta cattaagagt tcctgttttg agatttccca gatccagtag gtagttttcg
     3661 agattatttt caatatccat gactttttca atagcctgta tataatgttt tccgacttca
     3721 gttaactgta aaggtttggt acttcgatca aaaataggat aaccaatgcg gttttccaca
     3781 cgttttacat ttgcacttaa agaaggctgc gaaatgaaaa gagcagcagc agctttggaa
     3841 aagctttttt ccttgtatac ctcatagatg tattccattc cctgaaacat ataaactcct
     3901 ccgatatata atttaaacac tatatatttt ataaaaatat atgtatttga ttatattata
     3961 gcagagatat ataatgaggg caaatacatg ggagggcgaa taactatgaa aaaaacagac
     4021 tatcgtgtag aaagggattc tattggtgta aaggatattc cggaagatgt atattatgga
     4081 gtacaatcct tacgtgcggc tgaaaatttc cacattacgg ggctgaatat gcatccggaa
     4141 attattaaca gtcttgcata cataaaaaaa gcagcagcga taaccaattg tgaggtgggg
     4201 cttcttgaga agaaaaaagc acaggcgatt gtccaggcat gtgatgaaat tgtttcagga
     4261 aaattccata atgaatttat tgtggatcct gttcagggag gagctggcac atctttaaat
     4321 atgaatgcca atgaagtaat tgcaaatcgc gcgattgaga tactgggagg aaaaaagggc
     4381 gattatacaa ttataaatcc taacgatgat gtgaattgtg gacagtctac caatgacgtt
     4441 attcctactg ccggtaaaat gacttctctt cgtttgttgc agaatctgaa aaaacagctt
     4501 cttcgcctct atgatgctct taatgaaaaa gctacagagt ttgatcacat aataaaaatg
     4561 gggcgtacac agatgcagga tgcagtacca attcgtctgg gacaggaatt taaggcatat
     4621 tcggtagcaa tcatgcgtga tatccacaga atggataaag caatggatga aatgcggact
     4681 cttaatatgg gaggtactgc tattggaaca ggaattaatg cagatgaggg ctatctgaga
     4741 agaattgttc caaatctcac tgaaatatcg ggaatggact ttatacaggc ttttgatctg
     4801 attgattcca ctcagaatct ggatccattt gtagctgttt ccggtgctgt gaaagcatgt
     4861 gcggtaactc tttccaaaat gtcaaatgat ctccgtctga tgtcctccgg tccacgtact
     4921 ggttttgggg agattaatct tccggcaaaa cagaatggtt cctctattat gccaggtaaa
     4981 gttaatccgg ttattcctga agtagtgaat caggttgctt ttaatattat tggtaatgat
     5041 gttaccatta ccatggctgc agaggctggt cagctggaat taaatgcgtt tgagccgatt
     5101 attttctatt gcatgttcca gtctatcgat actcttggct atgcagtcca gacattggtg
     5161 gataattgta ttgtaggaat tacggcaaat gaagaaagat gccgttatct ggtagaaaac
     5221 agtgtaggta ttatcactgc aatcagcccc catcttggat atcagaaggc tgcggatatt
     5281 gcaaaaaagg caattaagac aggcgaatct gtaagaagtc tgattctgaa agaaaagctt
     5341 atggacgagg atgaacttaa tcgcattctg gatccgatcc atatgacgga acctggtatt
     5401 tccggaaaag attatcttat aaaaaaataa agaaaaaaac aggcgggaaa attttcccgc
     5461 ctgtaaaatc gtctggacac atatcatata taaatatgat ttttatattt ttgaattatt
     5521 cgattgattt caaccggatt agaacagacc tgtgatctta cctgtctcgt ctacgtcgat
     5581 tctctcagca gccggaactt taggaagacc tggcattgtc atgatctcgc ctgtaagagc
     5641 tacgatgaat cctgcaccag cggaaatctt caggttacgt actgtaactt cgaagtcagt
     5701 aggagcaccc agtttagtct ggtcatctgt taagctgtac tgtgtcttag ctacacagat
     5761 cgggcagttg ccaaagccaa gagcttctaa ctgtttcgcc tgtttctgag cgttagctgt
     5821 cagaactact ttcttaccgc catatacttt ctgaacgatc tggttcagtt tgtcttcgat
     5881 agaaccttcc agttcatatg cataggagaa gtcgtttggt tcttcaacaa gacggataac
     5941 ttcttctgca agtttgattc cgccttcgcc gccttttgcc cacacttcag aaagagcaac
     6001 gttaacgccc agttctttac atttagcttc tacaaagtca agctctgctt ttgtatctgt
     6061 agggaatgcg ttgatagcaa caacacatgg aagtttgtat acgtttttga tgttggaaac
     6121 gtgttttaac aggttcggga tacctttttc aagagcttcc aggttttcat tgttaaggtc
     6181 agctttagca acgccgccgt tgtatttcag ggcacgtact gtagctacga ttacaactgc
     6241 gcttggtttt aaaccagcca tacggcattt gatatcaagg aatttctcag caccaaggtc
     6301 agcaccgaaa ccagcttctg tgattgcata atcagcaagt ttcatagcca tctttgtagc
     6361 tgttacagag ttacatccat gagcgatgtt tgcgaatggt ccgccatgta cgattgcagg
     6421 aacgtgttcc agagtctgta caaggtttgg tttcagagca tcttttaaca gggctgtcat
     6481 agcgccttct gcgtgaaggt cacctgctgt tacaggtttc tgctcggaaa cttttccgta
     6541 tgtatatccg atgatgatct tggataatct ttctttcagg tctttgatgt cgcttgcaag
     6601 acagagaact gccatgattt cagatgcaac tgtgatgtcg tatccgtctt cacgaggcat
     6661 accgtttgtc tttccgccaa gaccatctac tacgttacga agctgacggt cgttcatatc
     6721 tacacatctt ctccatgtga tcttacgtgg gtcgatgttt aatgcattgc cctggaagat
     6781 atggttatcg atcatagctg ccagtaagtt gttagctgcg ccaatggcat ggaagtcacc
     6841 tgtgaagtga aggttaatat cttccatagg aacaacctgt gcatatccgc cgcctgctgc
     6901 accacctttt acaccgaata ccggtcctaa ggatggctca cgaagagcta ccataacact
     6961 cttgccaagt ctctgcatac catctgcaag acctacagta gtagtagttt taccttctcc
     7021 tgctggagtt gggttgatag ctgtaacgag gattaatttt ccatccttct tatcactttc
     7081 tttcagaaga ttgtagtcga tttttgcttt gtattttccg tactgctcca gatatttgtc
     7141 gtcaatacct gctttctctg cgatctgagt aattggaagc atctcgcatt cctgtgcaat
     7201 ttcaatgtct gatttgaatc ccataattgt ttttctcctt tcgtttccgc ataacatgaa
     7261 aaacttctgt tgctgttcac tccgcgatca gcaacaatta ttaattgaaa gaagtattgg
     7321 ccggtctgcc tggtattcct gatttctgcc ctgaaagtta taaaaaaagg ccagtatctg
     7381 aatatttcaa atactgccca gacggtcggc tcccacaaac ctccgactcc acgtggtttg
     7441 cactccactc tttccgtcag tactcgaagg ttctttcaat tgatgaatac aatatatcat
     7501 tttgagaaaa aaatgtcaag aaatttttgt tgaaacgtca aaaaatgtga gtaaactgga
     7561 taaaagttgt gcaaattgat aagagaagag aatcgtaatc cctggtaatg aaagaaaata
     7621 cgttttctca agggaagaaa ttgttaaaaa ataaacacag ttttccctga taaatgaaga
     7681 aaatataaaa agcgggtaaa gctagagcgt gtctgaaaaa tcattcccgc aatctgcacg
     7741 cccccacttt gcgggatatt tcacccgaat tcagttgccg tagcccgcta cggcgccctc
     7801 atccgggcaa aatatcccac aaattgtgac gcacatcttg cagaaagcct ttttcagaca
     7861 cgctctagtg caaaatatgg aaaatggaat tgacaacagt tcagaagata tgttattctc
     7921 atctttagta tgaaaagaca ctatcgtttt catgcaaata tttgctcaca ttcagagaca
     7981 gtttctgaat gttaagccat acggacaggc ggggcagttg ccgggtggga gacaccacat
     8041 tattgattga gttagaagct caaattttat aagttgatta ctttataata atcagtgcgt
     8101 aagcacacat catcttgtga aacggtcaat aagagcatag catatatttg ccagcgattg
     8161 aagacgacag cagtcatgaa tatttcagaa tacgggaaca ggcacaggat acagacggat
     8221 ttatacggga aatccggtca gtatataaag agacagagcc tgagaaattc tatagatcat
     8281 gagagaagca gatggtgaat gaacttatct gcttcttttt tgtgcagata tagcagatat
     8341 aaaggatatg gttggagata aacgctttgc ggggatgtgt agcgattcta tagaatcgtg
     8401 tgccgagtct cacatgcgtt cgacttgaat atatagagaa ataattgaat cattgtgccg
     8461 gttttgagcc agtatacaat tgctgtatga ttgaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgttggac aatctctgcc atccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcac atgcatttct tatggtagga ggaaccacat
     8821 ctgcagtgca gagtatgatc ctttctgtct gtaaggcagg ggacaagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg tggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgca cagctgggta tctcccttgg catggaggtc agccaggtgg
     9001 agaaggctat ggatgagaac ccggatgcgg tggcggttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatttg cggactatcg taaagaaggc tcatgccaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agtgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggaaatcaat gagatcggcg gctattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ttgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agagactggt aggggcactg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtatttt ctgacaagga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg attatcggtg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agtattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcaga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggcggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggattatg atgagaaatt taagaaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaatggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct atgattttcc tgaggtagga
    11581 aaaaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa gaatattccg
    11641 ggagtacaga gaatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaacgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgcgct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcta cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgtctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaataccgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcgcaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt cccaagctca gatggagaat gcaaagaatc
    13501 agcttggaaa tgtttccggt gtgactttgc tggaatgcga gacagatgat gcctgggcga
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgata
    13681 gagtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaagacc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gtagaggaaa accctgcagt
    14701 gcgtcatttc agcagagtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg ggaagaatct
    14821 cggcatttat cgaaaaacac atattccgga tgatcattat tatcaggaaa aattctattt
    14881 cacaccggga gacaccggct ttaaggtttt tgataccaga tttggaacca tcggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac agcaagatgt atggcgttgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgagcccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggttcct cttttattac agataacaca ggtgctctct gcgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgat ttggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa attccattgc cacaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgt agtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagcagga aagttttgac atgtatttct ggcaaaatgg agtgtaaaag atgaacagaa
    15601 aagaattttt ggaaatcctg agaagccagc ttgccggtca gatgcaggag ggcaaagcag
    15661 cagcacatat caggtattat gaagattata tacagtctca ggtacgtggc ggacgttcag
    15721 agcaggaagt actgcaggaa ctgggagacc cacatctgat agcaaagact ctgatcgata
    15781 cagatgatgg aagtacacag gaagattacg gagagtattc ttcttacgga agcagctatg
    15841 gcaatgagac agagcttcct catcagcaag agaaacgatg gaaaaaagta atcgatcttt
    15901 ctacctggca tggcagggct gttgttattg cagcagcggc tgttataatt attttactga
    15961 tactgataat cggagttgcg attccgtttt ttattattct tgcaattatt ctttattttc
    16021 tttcatggct gaagaaaaga aataatcaat gaaaatctat gcagggtttc agaaaagaaa
    16081 ccctgcgcaa aatcttaaaa attttaaaaa tctaaaaaat cttaagtgta aacattcttg
    16141 tttcacgata ttaattcccc ttgaatattt ataatcatat aatttcaact tatttctatt
    16201 cgttaatcct gccttgtgca gggaaaaatc ccacattcat ttttatattt tttgttcgga
    16261 aaggagacgg aaaatgaaac acaatttcaa actgaaagaa cgccttggag ctttgctgct
    16321 tgcaatgctt tttattctgc aggcaattct ggggcttgtg cctgtctgtg taactcaggc
    16381 ggcaccgtta actgtagaaa catgggacag tgacaaggtg gtagattatg gttatcgctt
    16441 taacatgaag tttcagcccg gaattaccac atatgaatct tttgggtgtg ataatctgga
    16501 cagggaagct ttttcagaca atggaaaaag cgaacgtgac acagagtgcg ttcgtgtagg
    16561 agcggactat aaagccggaa gcgcagggat gcgttataac aatgtaggaa aagatggaaa
    16621 tggaaatatt gttgatgtca gactcattct tgtgggagta gagaatgcag aacctcgtta
    16681 tgatctgcgc actgcagaat cgattgttca gaataaaggc ggagctacgt ttgcatggaa
    16741 agataatgaa gcttatccaa tggttggctt ttccaaaaac agtatcggtg tatttattta
    16801 ttctgtagga tacgcaaagg ttaagtttca gtttctgaag catggaacag aagaaacact
    16861 gccgatcagt ggccatggaa ccatacgtga tattgatgcg ggacagggag tccgtattcc
    16921 gtcagacagc agtctggata atgcatatgt tctgaaaaac aatgattatc tgacggtaga
    16981 tggaaattct gtaagctcac cccttggttc cgttgagccg gatgatccga gaggatggct
    17041 gaatcttttt tatgatacag ataattttac ggtagaattc tgtcatcagt tcagactgga
    17101 taaatgggat aaaagtcgtg aagatgccat tgcaaaagcc ggttctcagg aaagatgggc
    17161 agagattaca agaaataaat atctggatcc atcaggcaac agttattgtc cgaactttaa
    17221 aggacagaaa tactgcaaag catatgcata ttttgatttt acatcctatt gtttcggtga
    17281 tgttgagatg aaaaaagcgc ctgagaaacg tgtgggagag gcaaactgta catgggaaca
    17341 ggcagctacc gcatcaaaag aaaaaccttt tggcattcgt cagggacagg aatttcagta
    17401 tatgatccgg gcagaggtga cacccaatag actgaaatcc tttgtggtac aggatatact
    17461 tgaggattgt cttactatag aggatgcatc aaaagtcagt attgtgaatg atgcagggca
    17521 gacagtgaca gactggtttg atgttgctgt tgaaggacag aaagtgacct gcagggccaa
    17581 agcagagagc cttcaggatg aagcatttac agataatcag acttacacat ttactttaaa
    17641 agtacgccag agaccggaat cagaaattaa catttcaaaa taccttgcag aggatggata
    17701 cagtattctt gtaccaaacc atgcatccat gagttatgaa cgtacaaacg gaagcggaga
    17761 tacaatggat acggaaacag tgtgggtaaa gggtgtgatt ccaccggaac tggaagtaaa
    17821 gaaaaatact tctcagtatg aatggaaaac gggagatatc atagattatg agattctggt
    17881 ttctcagaca aaacaggatg taaaagcagt aaatgttgtt attacagacg agcttccatc
    17941 atgtctgcag cttctggaag ggcagtatgc tgtagagaca agtcagggag gtgagaactg
    18001 tacgcttacc ggacagggag aaaatggatg gaaagcagag tgtccgtccc tgaagtatgg
    18061 ggagatgatc acaatccgtt ttaaatgtca ggcatctgcg gattccaatg gacaggaatg
    18121 ggaaaatatt gtgactgcaa cagcggataa tctgatcaat cctgagacag gagaacagga
    18181 atccagaaag gatatggcag aagtatggcc gaacagtcca cagcttgaaa ttgataaaac
    18241 agcagacaaa tatgaatggc aggcaggaga gcaggtagct taccggatcg tggtgaataa
    18301 tgtaacggca ggaacaattg caaaagatgt aactattact gatattggtc tgccgcaggg
    18361 actggttctg gcaggtggtg cacagagcat ggaagtactg ggagttcagc aacaggtaaa
    18421 ctatcccgta ccggataaga aaacaggaca ggcatatgaa gcgagacttg tggattctca
    18481 gttgaatgca gatgagaacg gattttcctt ttattgttct tatgtgccat acagtcagcc
    18541 tgtaacgatt attttccatt gtatcgcaca ggaagaggca aatggacacg aaagcgtaaa
    18601 tgcagcaact gtaaaagctg ctaatacaga tgagaaatct gatgatgcag aagtatatgt
    18661 aaattcagga gaattctgga ttgagaaatc tgcagatcat tatgaatggc aggtcggaga
    18721 acaggtacag tacaatgtgg tggtggagaa taaaaaagca ggtacagtgg cccggaacgt
    18781 aactgtctgg gataccggta tgccggcagg acttgcgctt tcatcggcag aggatgtatc
    18841 ggtaagcgga atcccacaga gtattacgca gctgacagca gggaccgaag atgttttgaa
    18901 ccagctgaat ccggaatttt ataatgagac atcagagaaa ccggtgaatt atgaatttct
    18961 tcaggaggga agcggatgga gactgaacat ttcagatctt ccggcaaata ctccggttat
    19021 gatttctttc ctttgcacag ttacggaagc ggcaaatgga atggaaagca ttaatgttgc
    19081 caatgtgcaa gcgcagaacg cccctgtttc gcaggatgac gcagaagtgt atgtaaatac
    19141 agcagttctt tctattgaga aaagttttca gaatccatat ctggcagccg gggacggacg
    19201 tgcggaaaat gaatttcggg taggggaaca ggtgaattat caggttacgg ttaataatct
    19261 tcagaaggga tctatcgcaa gaaatctggt gatcagtgat ctttcccttc ctgaagggct
    19321 ggctctggac ggagctgaag atgctgttac tgtaagcggt gttccggctg ttattcagaa
    19381 tccggtggca ggaactgatg atgcaggaaa tcagctgaat ccggaaaatt ataaagaaac
    19441 agtggaaaaa ccggtcagct gtcaggttac acgtcaggga accggatgga tcgtgacgat
    19501 ttcagatctt ccgtatcaga cacctgtgac tgttaatttc cgctgtactg cgcaggaaag
    19561 cgtaaatggg atggagattg taaatacagc acaggcatat gcagataatg cacagaaagt
    19621 aaaggactcc ttaaaaatct gggtgaactc gcctgttctt aaagtagaga agacgacaga
    19681 caaaccattt tacaaatatg gtgatattat tacataccgc attgtcctga tacaggagca
    19741 gaccggatgt gtggcgcgta atgttacttt gcaggatgtg atcgatactc agggagtacg
    19801 tcttctgaag gattcggtga ttctgatgga tgagaaagga aatgtggcag atgctgatgt
    19861 acagatcaat gatgataata ctttcctgat gtcaacaggc aggacactgg tcagggatcg
    19921 cagatatagt atctgcgata atgataaagg cggtcttttt gagcaggtaa tgtataatcc
    19981 tctggactgt caggaacaga aaagtatgat cgtggaatat caggcagcgg tgattgatgc
    20041 agccctggca ggacagaaag tgcacaatac tgcagttgca gacagcagtg aaaagatacc
    20101 tgcaaccggg gaagcagaga cagaggtaca cagtccgatt ctggaaattg tgaaggaatc
    20161 agataagaaa gagtatgcgt ccggtgagaa aggatactat aaactgacag taagacaact
    20221 gcgtgaggat gtcacagatc agaatattgt tatcgaagat aaactggaaa cccaaggggc
    20281 ttccattgta aaagacagca tttttgtgaa gaaaaacggt atagaactga aagatgccaa
    20341 aatagaggca gatgatacag gatttgtaat tcagacagga gcatcgttgt cagatatgga
    20401 taaaattgaa gtctgctatg aaatggtatt taaaacagaa agcacagagc ctgaaaaaat
    20461 tgtaaacaca gcgaaagcaa gaggtgatat ttcaccggaa attactgcac agcaggaggc
    20521 atatgtgaaa gcaaaagcag aaccgactgt cacaccaaca ccgtctgcaa caccgaaacc
    20581 aacagaaaca ccaaagccga cagagacacc aaaacctaca gaagtaccga aaccgacgga
    20641 gcagccaaaa gccacaccaa caccatctgt accgggaacc tgcccgaaaa tgactcctgt
    20701 accgacgaaa gcaccgttgg catcttacaa tggtggaaat aatggaggca cgacttccgg
    20761 aagcggaggc agcagttacg caaattcggg tggatattcc ggtggatatg gaagctatca
    20821 gggtggttcc atggcaggaa gttctaaaac aggagatgtc agaccgttta aaatgatggc
    20881 tgttcttgga cttatcggaa tgggactgct gacaggaggt gtggtgatct acagaagaac
    20941 tgtttccggg aaaagaaata taaagggtat gccgcggaaa tgaaaaaact cagaacattt
    21001 gcagtaagta tgatcatagc agcaattggg cttcttatat attgtgccgg cttctatata
    21061 aaaagttatg aacagaatct tgcagcaagg caggaatatg cagagctttc ccaaatggca
    21121 ggggtgaaga acagagaagg tgccggatta ttggcagatg gcaaaaaaac tgatgaagac
    21181 agcagtacaa aaaacagtga aaaaaaacgc aggaaaaaac agagaagatc ttctgaatca
    21241 aaaaacaaaa actgtacaga tgaaatcagg gaatccttcg ggatttcctg ggaaaattta
    21301 agaaagatca actctcagac agttgcctgg attactgttc cgggagccga tatttcttat
    21361 cctgtagttc aggcggcaga tgatgaatat tacctgaaac ataatttcag aggagaggaa
    21421 gatctgtttg gatgtatttt tctggaacat gacataaaaa agaattttac agattcccac
    21481 agtattcttt acgggcataa tatagaaggt aatatgatgt ttgcaaatct gaaccgttat
    21541 gaacagcctg aatttctgaa aaaatgtcct gaaattgaga tcacaacacc aaaaagaaag
    21601 tttctgtaca aaattttttc tgtggaacag gcatcttccc aaagcccggc atttgaatat
    21661 ggatacaagt tatccagtcc tgcatacagg agacaattat ctatattgaa aaataattcc
    21721 atgtatgaca caggagtaga gcctgatgaa agggagagaa tggtgactct gatcacctgt
    21781 aattcacatc tggataaaga aatacgtatg gcggtacatg ggatttgcca tgaatgttat
    21841 ggtatagaaa aagctgagcc gaagtgatgt tgaaatcaat cggatattgg taactttcgt
    21901 aaaggatgaa ctgttactgt tcacacatca ctatccctcg aggtgttttg gaaaaaacta
    21961 atgaaaaatc tctcgatatt ttgtataatt tatgcataaa aaacaacttg ttcgtacgtg
    22021 cgtacaagtt gtatcctaaa tacaggaggg aagaagacat gacagataat ggaaagccga
    22081 aatatttctc actgatggaa cagctcagaa gtgatattat gtcaggagct atccgaccgg
    22141 gagagaagct tccttcagaa aacgagcttt cacagaaata ttccctgagc agacatacag
    22201 ttcgtaaagc actgggaatc ctggagcagg acggatatgt agaggcattt cacggaagag
    22261 gtacttattg ctctgagaat atgcgccata taaagaattc aaagaatatt gcggtagtga
    22321 ccacatatat ttctgattat atttttccga gactgataca gggaatggat aatgtccttt
    22381 cagaaagcgg ttatagtatt atcctgaaaa acacagcaaa cagcagacag aaagaggcca
    22441 gatgtctgga ggaacttctg aagaaagata ttgatggact gatcattgaa ccaagcaaaa
    22501 gtgagatgat ctgtaaacac agaaatcttt atcagaatct ggataaattt gaaattccgt
    22561 atgtgtttat tcagggaatc tattcagaaa tgagggataa acctcatatt cttatggatg
    22621 atgcacaggg aggctatctt gtaacaaaat atctgctgga actgggacat aaaaaaatca
    22681 agggtttctt taaggcagac gatatgcagg gactggagcg ccacaaggga tatgtgaagg
    22741 ccttacagga gtcagggatt gtctatgatc ctgatgatgt tgtctggttt catacagagg
    22801 acaggaaagt aaaacctgca ctgatggcaa aagaaatggt acagagcgga cagcttccgg
    22861 atggaatcgt ctgttacaat gatcagattg ctgttcaggt tatggaagaa ctggagaaaa
    22921 tgggagtcag gataccggat gatatttcca ttaccggtta tgacaattca ctgtatgctc
    22981 agcgaggaag cggaatcaca acgatagctc atccgcagga aaagctggga gaaatggcag
    23041 cagagcttat acttgagaag atcaacggag ttcctgaaga agaaagtaag gttgaaagac
    23101 tgatttatcc ggaactgatc atacggggat catgcagaaa aatattgtaa acaaatgaaa
    23161 taaataaaaa ataaaaataa atccaggagg aattttatca tgaaaacagg aagaaactat
    23221 aagttctggt tttgtacagg ttcacagga
//
