LOCUS       c00045_gnlPro..        18326 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMLIJEHL_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 01:02:09
            Original ID  :: gnl|Prokka|BMLIJEHL_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18326
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18326
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7300:11545](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7301..11545
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     protocluster    1..18326
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[335:11545]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      336..11545
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="2"
     cand_cluster    1..18326
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="chemical_hybrid"
                     /product="TPP_AA_metabolism"
                     /product="Others_HGD_unassigned"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..18326
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2..352)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-21, bitscore:
                     66.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVYNFSAGPAVLPEEVLKEVAEEMMDYQGTGMSVMEMSHRSAD
                     FQKIIDEAEQDLRDLMKIPDNYKVLFLQGGASQQFAAIPMNLMKNKVADYIVTGQWAKK
                     AYQEAQKYGKANK"
     CDS             complement(336..2027)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-55, bitscore:
                     176.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLTGAEIIVECLKEQGVDTVFGYPGGAILNVYDALYEYKDQITH
                     VLTSHEQGASHAADGYARATGKVGVCLATSGPGATNLVTGIATAYMDSVPMVAITCNVG
                     TPLLGKDSFQEVDITGIVMPITKHSFIVKDITTLADTVRRAFYIAKSGRPGPVLVDVTK
                     DVTGAKYEYTACAPAEITPKTDTIKDEDIATAVQMIKEAKRPFIFTGGGTIISEASREV
                     TELAHRIDAPVCDSLMGKGGFSGEDPLYTGMLGMHGTKTSNLGVSGCDLLIVLGARFSD
                     RVTGNTKTFAKNAKILQIDVDAAEINKNIVVDASVVGDEKEVLKRILAEVPEMRHSEWT
                     AHISELKEKYPLRYDHSQLTGPYIIEKLYELTKGDAIITTEVGQNQMWAAQYFKYKEPR
                     TFLSSGGLGTMGYGLGAAIGAKMGRPDKTVVNIAGDGCFRMNMNEIATAVRCGRPLIEI
                     VLNNHVLGMVRQWQTLFYDHRYSHTILNDAVDFVKLAEAMGAKAIRITKMEEVEPALKE
                     ALACPGPIVLDCMIDQDLSVFPMVPAGASIDDIFDEEDMKNNEQSV"
     CDS             complement(2103..3776)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="ILVD_EDD (E-value: 8e-230, bitscore:
                     753.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDAVKTGTQQAPHRSLFNALGMTKEEMDRPLVGIVSSYNEIVP
                     GHMNLDKITQAVKLGVAMAGGTPVMFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTEAM
                     AMAHQFDALVMIPNCDKNVPGLLMAAARLNVPTVFVSGGPMLAGHLNGHKTSLSSMFEA
                     VGAYAAGKLDEDGLTECEMKTCPTCGSCSGMYTANSMNCLTEVLGMGLKGNGTIPAVYS
                     ERIRLAKHAGMQVMEMYRKNIRPRDIMTKEAILNALTVDMALGCSTNSMLHLPAIAHEI
                     GMDFDISFANEISAKTPNLCHLAPAGPTYIEDLNEAGGVYAVMNELNKKGLLHTECMTV
                     TGKTVGENIKDCVNLNPEVIRPIDNPYSQTGGLAVLKGNLAPDGGVVKRSAVVEEMMVH
                     EGPARVFDCEEDAIAAIKGGKIVEGDVVVIRYEGPKGGPGMREMLNPTSAIAGMGLGSS
                     VALITDGRFSGASRGASIGHVSPEAAVGGPIALVEEGDIISINIPELKLEIKVSDEEMQ
                     ARKAKWQPREPKVTTGYLARYAAMVTSGNRGAILEVPKAK"
     CDS             complement(3884..4966)
                     /locus_tag="ctg45_4"
                     /transl_table=11
                     /translation="MDYKIALIPGDGIGPEIVREAKKVLDKVCEKYGHSFSYSEVLLGG
                     ASIDVHGVPLTDEAIATAKSSDAVLMGSIGGDAKTSPWYKLEPSKRPEAGLLAIRKALN
                     LFANLRPAYLYNELRKACPLRDEIIGDGFDMIIVRELTGGLYFGERQTIEENGVKKAID
                     TLSYNENEIRRIAIKAFEIARKRRNKVTSVDKANVLDSSRLWRKVVEEVAKDYPDVTLE
                     HMLVDNCAMQLVRDPKQFDVILTENMFGDILSDEASMVTGSIGMLSSASLNETKFGLYE
                     PSHGSAPDIAGQDKANPIATILSAAMMLRFSLDMDKEADAVEAAVQKVLTEGYRTGDIM
                     SEGCKLVGTKEMGDLIAAAL"
     CDS             complement(5155..5454)
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MDASSGMGMVGAIVWMVVLFGIMYFLMLRPQKKEQKRLQAMLNDM
                     EVGDSIVTTGGFYGVVIDMTEEDVIVEFGNNKNCRIPMRKQAIAEVEKAGSAAE"
     CDS             complement(5703..6854)
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="MAEYKLLKTEGRAKRAEFHTVHGTIQTPVFMNVGTIGAIKGAVST
                     MDLQQIGTQVELSNTYHLHVRPGDKIVKQLGGLHKFMVWDKPILTDSGGFQVFSLAKLR
                     KIKEEGVYFNSHIDGHKIFMGPEESMQIQSNLASTIAMAFDECPSSVADRDYVQKSVDR
                     TTRWLARCKAEMARLNSLPDTINKEQLLFGINQGAVYEDIRIEHAKAISEMDLDGYAVG
                     GLAVGETHEEMYRILDAVVPYLPQNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNG
                     RHGHVYTNHGKMNLFNAKYELDTRPIEEGCQCPACQHYSRAYIRHLLKAKEMLGMRLCV
                     LHNLYFYNHMMEEIRDALDAGNFAEYKKMRLEGFEEGKINSKR"
     CDS             7301..11545
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_7"
                     /sec_met_domain="HGD-D (E-value: 9.7e-64, bitscore: 205.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5.4e-38, bitscore:
                     120.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKTLGIDIGSTTVKIAILDENENLIFADYKRHFANIQETLADL
                     LQEAFDQYGEMTLHPVITGSGGLTLANHLGVPFTQEVIAVSTSLQKLAPKTDVAIELGG
                     EDAKIIYFENGNVEQRMNGICAGGTGSFIDQMASLLQTDATGLNEYAKDYKALYPIAAR
                     CGVFAKTDIQPLINDGATKPDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLHFLS
                     ELRESFIRTLKLDGEHTIIPENSHLFAAIGSALNAKEDNSISLTEMKDRLRNSIKLDFE
                     VERMEPLFASQEEYDAFAKRQSSYKVKTGDLATYKGNCYLGIDAGSTTTKTALVGEDGT
                     LLYSFYSSNNGNPLKTTIRSIKEIYELLPKDAKIAYSCSTGYGEALLKAALLLDEGEVE
                     TVSHYYAAAFFDPEVDCILDIGGQDMKCIKIRNKTVDSVQLNEACSSGCGSFIETFAKS
                     LNYTVQDFAKAAVFAQHPIDLGTRCTVFMNSKVKQAQKEGAEVSDISAGLAYSVIKNAL
                     YKVIKVSDASELGKHIVVQGGTFYNDAVLRSFEKIAGCEAIRPDIAGIMGAFGAALIAR
                     ERHQEGAETTMLSIDKINELKYTTSMANCRGCTNNCRLTINKFSGGRQYVSGNRCERGI
                     GKEKNKDHIPNLYEYKYKRIFSYTPLTADKATRGKVGIPRVLNMFENYPFWYTFFTELK
                     YEVVLSPTSTRKIYELGIESIPSESECYPAKLAHGHVTWLIRNGVKFIFYPCIPYERNE
                     FPDAVNHYNCPIVTSYAENIKNNVDELNDPSITFRNPFLAFTSEEILANRLVEEFKDIP
                     AEEVKAAVHKGWEEMAAARRDVQKKGEETLKYLEDTGRHGIVLAGRPYHIDPEIHHGIP
                     DLINSYGIAVLTEDSISHLAPVERPIRVNDQWMYHSRLYAAANYVKTRDDLDLIQLNSF
                     GCGLDAVTTDEVYEILDGSDKIYTCLKIDEVNNLGAARIRIRSLIAAIRAKKAQGQKRT
                     VKPASIDKVSFTKEMRKDYTILCPQMSPFHFSLLQAAFNSCGYNLEVLPNDNKHAVDVG
                     LKYVNNDACYPSLIVVGQIMDALLSGKYDLNKTAVVMSQTGGGCRASNYIAFIRRALKK
                     AGMEQIPVISVNLSGLESNPGFKLTLPLVKKVAYGAVFGDILMKCVYRMRPYELEEGIV
                     NRKHKIWEQRVISFLSGSSISHSQFKKMCREMVHEFDTIPISDVKKPRVGIVGEILVKF
                     LPAANNHLAELLESEGAEAVVPDLIDFMCYCFYNQNFKVENLGFKKSKATMANWGIKAI
                     EWVRKPASEALAQSRHFAPPADIRNLAKMASPIVSTGNQTGEGWFLTGEMMELIHGDVP
                     NIVCIQPFGCLPNHIVGKGVIKEIRREYPTANIVAIDYDPGASEVNQLNRIKLMLSTAQ
                     KNLKKAEEKMHK"
     CDS             complement(11784..13412)
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MNQKNNLVKNASFLMIAAMISKVIGLLYKSPLSNIIGSLGMGYTS
                     LAQNAYMILLMIASFSIPQAVSKLISERIALKDYRNAHKFFKGAMIYAMVIGGVVGLFC
                     LFGAGLIIPQNQKDAIPALQILAPTIFLSGILGVFRGYFQAYRNMMPTSISQIIEQVFN
                     AAVSLLAAWGFINAFSDGTENSIAKWGAAGSTVGTGAGVVTALAFMLLVYGVNRRKILH
                     RVERDHRHQEESYKEIFRVIILVVSPIILSAFVYNVNAYINGYLFSDILGRRGGDAAQI
                     GILYAEYATYFMTIINIPLTLSSTAPTSMIPEVSALYATEDIEATRECIDQTVQLSMVV
                     SAPCAMGLAVLAQPIVFLLYGNSTGLAANLLILGSFSILLNGMSNISNGVLQAIGQQRI
                     PVITAAIALVVDIVVVVVLLFTTNLGVYALLIAMVIYSVVVCVLNDRAMKKYLQYKNPW
                     KEGYLYPVLASVPMGIVAGCICYGLNIFVKSNFICLIVSIPVAAVVYLFAYLIISKPSE
                     SQLRRIPGGSYLIRIAEKLPFWQNN"
     CDS             complement(13458..14132)
                     /locus_tag="ctg45_9"
                     /transl_table=11
                     /translation="MSAISGDWLEALKGEFHQPYYAKLYKTVMTEYQTRKIFPPADDLF
                     NAFHFTPLNEVKVVILGQDPYHNDGQAHGLCFSVKRGVETPPSLVNIYQELHDDCGCYI
                     PNNGYLEKWAKQGVLLLNTVLTVRAHQANSHRGIGWEQFTDAAIQVLNEQDRPIVFLLW
                     GRPAQMKKSMLNNPKHLILEAPHPSPLSAYRGFFGCKHFSKTNEFLVANGLEPIDWQIE
                     NI"
     CDS             complement(14165..14923)
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="MFTKRIIPCLDVNNGRVVKGVNFVQLRDAGDPVEIAKAYDAAGAD
                     ELVFLDITASCEQRDTVVDMVRRVAANVFIPFTVGGGIRTVDDFKKLLREGADKISVNS
                     AAIDRPELISEAADKFGSQCVVVAIDAKRREDGGWNIYKHGGRLDTGIDAIEWAKKVEA
                     LGAGEILLTSMDCDGTKAGYDLALTRAIADAVSIPVIASGGAGTLEHFYDALTEGGADA
                     ALAASLFHYKELEISQVKDYLSDRGISVRR"
     CDS             complement(14925..15563)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_11"
                     /sec_met_domain="GATase (E-value: 4.9e-31, bitscore: 97.8,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAIIDYDAGNIKSVEKALHYLGEETTVTRDPQTLLNADKVILPG
                     VGSFGQAMENLHTYGLVPVIHEIVEKKTPFLGICLGLQLLFESSEETPGVEGLGILKGK
                     IVKIPPAPGLKIPHMGWNSLHFQNNGRLFQGIPEQTYVYFVHSYYLQAEEPEIVKATTE
                     YSTCIHASVEKDNVFACQFHPEKSSKWGLKILENFAAVGKDGNTEKEGK"
     CDS             complement(15783..17327)
                     /locus_tag="ctg45_12"
                     /transl_table=11
                     /translation="MTGNGKTDKKFHTLQHQISVVFICLLLLSIFTITLINGLFLEKYY
                     VSKKVEVLEEAKEVLSQMNLDDILQYDTDIEEDKKGATDEISDEIERSSSRNNLTWIIV
                     NEENSGYYYWGENNMAKMLRSKLFGYINNLDQDMQHSRVLKKTDTCTMWQVHDRFAGME
                     YVECWGQFDNGYYFLIRSPLESIKESASISNSFYFIVGIIIIVVSGIVILVMTNRITRP
                     ISELTKLSEKMSDLDFDARYQSRAGNEIDVLGDNFNKMSRKLESTISELKSANNKLQKD
                     IEDKIKIDEMRKEFLDNVSHELKTPIALIQGYAEGLNENISDDPESREFYCEVIMDEAS
                     KMNKLVKNLLTLNQLESGKDAPVMERFDIVSLIRGVLGSMHIMIEQKEATVIFEETEPV
                     YVWADEFKIEEVVTNYTSNALNHLDGERKVEIKVLQEEDCVKVTVFNTGTPIPEEDIPN
                     LWNKFYKVDKARTREYGGSGIGLSIVKAIIESMNQKYGVCNYDNGVEFWFTLDCRQ"
     CDS             complement(17324..18004)
                     /locus_tag="ctg45_13"
                     /transl_table=11
                     /translation="MDTLKILVVDDESRMRKLVKDFLTKKNFQVLEAGNGEEAMDIFYE
                     EKDIALIILDVMMPKMDGWEVCREIRKNSKVPIIMLTARSDERDELLGFDLGVDEYISK
                     PFSPKILVARVEAILRRTGQNNPEDVISAGGIVIDKAAHLATVDGKPMELSFKEFELLT
                     YFLENQGIALSREKILNSVWNYDYFGDARTIDTHVKKLRSKMGDKGEYIKTVWGMGYKF
                     EVDE"
ORIGIN
        1 tcttgtttgc ttttccatat ttctgtgctt cctggtatgc tttctttgcc cactgtcctg
       61 ttacaatgta atcagcaacc ttgttcttca taaggttcat ggggattgct gcaaactgct
      121 gggaagctcc gccctgaagg aataatactt tatagttatc cggaatcttc atcagatcac
      181 gaagatcctg ctctgcctcg tcgataatct tctggaaatc agcgcttctg tggctcattt
      241 ccattacaga cataccagtt ccctgatagt ccatcatctc ctctgcaact tctttcagta
      301 cctcttccgg cagtacagcc ggtcctgcgg aaaaattata cactctgctc attgtttttc
      361 atatcctcct catcaaaaat atcatcaatg cttgcgcctg ccggtaccat cgggaatacg
      421 ctgagatcct gatcgatcat acagtcaagt acgataggtc ccggacatgc cagagcctct
      481 tttaatgcag gctctacctc ttccatcttt gtgatacgga ttgcttttgc tcccatggct
      541 tctgccagct tcacaaaatc tactgcatca tttaaaattg tatgggaata tctgtggtca
      601 tagaacaagg tctgccactg acgcaccatt cccagtacat gattgttcaa tacaatttca
      661 attaaaggtc tgccacagcg gactgctgtt gcaatttcat tcatattcat acggaagcat
      721 ccgtcacctg cgatatttac cacagtcttg tccggtcttc ccatcttggc tccgatggct
      781 gctccaagac catatcccat agttcccagg ccaccggaag aaaggaaggt tcttggctct
      841 ttgtatttga aatactgagc tgcccacatc tggttctgtc caacctctgt tgtgatgatg
      901 gcatctcctt ttgtcagttc gtacagcttt tcaataatgt atgggcctgt aagttgggag
      961 tgatcatatc ttaacggata tttttccttc agttcactga tatgtgcagt ccattccgaa
     1021 tgtctcattt ctggaacctc tgccagaata cgtttgagaa cttctttctc atctcctacc
     1081 acacttgcat ctactacgat gtttttgtta atctctgcag catctacgtc aatctggaga
     1141 atcttcgcat tctttgcaaa ggtctttgtg tttcctgtga cacgatcact gaatctggct
     1201 cccagcacga tcaggagatc gcagcctgag acaccaagat tggaagtttt tgtcccatgc
     1261 attccaagca ttcctgtgta cagaggatct tctccggaaa atcctccctt acccataaga
     1321 ctgtcacata caggagcgtc gattctgtga gcaagttctg tcacttctct ggatgcctct
     1381 gagataatcg taccgccgcc tgtaaaaata aatggtctct tcgcttcttt gatcatctgt
     1441 actgcagttg caatgtcttc gtctttaatg gtgtctgttt tcggtgtgat ctcagcagga
     1501 gcgcaggcag tatattcata tttcgcacct gtcacatcct tggtcacatc tacaagcaca
     1561 ggaccgggac gtccgctctt tgcaatatag aatgctctgc gtacagtgtc tgccagagta
     1621 gtaatgtctt ttacgataaa gctgtgcttt gtaataggca ttacaattcc tgtaatatca
     1681 acctcctgga aagaatcctt tccgagcagc ggtgttccta cattacatgt gattgccacc
     1741 attggtacgg aatccatgta tgcggtagcg attcctgtta ccagattggt agctccgggg
     1801 ccggaagttg caagacacac gccgacttta ccggtagctc ttgcgtatcc gtctgctgca
     1861 tgggatgctc cctgctcatg ggaggtcagt acatgtgtga tctggtcttt atattcatag
     1921 agggcgtcat atacattcag gatggcaccg cccggatatc cgaatacagt gtcaacgccc
     1981 tgttctttta aacattcaac gatgatttca gcacctgtaa gctgcatctt tacatatcct
     2041 cctaactttt caggcaggaa tcacaggtta tgctgcaatt cccgccgggt acttgttcat
     2101 ctttattttg cttttggtac ctcaaggatc gctcctctgt ttccggaggt taccatggca
     2161 gcatatcttg caagatatcc tgttgttacc tttggctcac gaggctgcca ttttgctttt
     2221 cttgcctgca tttcttcatc ggaaaccttg atctccagtt tcagttccgg aatgttgatg
     2281 ctgatgatat cgccctcttc aacaagtgcg atcggtccgc cgactgctgc ttccggtgat
     2341 acgtgtccga tggatgctcc tctggatgca ccgctgaaac gtccgtctgt gatcagggct
     2401 acggaagatc ccagtcccat acctgcgatt gcagatgtag gattcagcat ttctctcata
     2461 ccagggccgc ctttcggtcc ttcgtaacgg ataactacta cgtcaccctc tacgatcttg
     2521 ccgcctttga tagctgcgat tgcgtcttcc tcgcagtcaa agactcttgc aggtccttca
     2581 tggaccatca tctcttctac aactgcagaa cgttttacaa caccaccgtc cggagcaagg
     2641 ttacctttaa gtactgcaag tccgcctgtc tggctgtatg gattgtctat cggtctgata
     2701 acttcaggat ttaaatttac acaatctttg atgttctcgc ctactgtctt gcctgtaact
     2761 gtcatgcact cagtatgaag aagtcccttc ttattcagtt cgttcataac tgcgtataca
     2821 ccgcctgctt cgttcaggtc ttctatgtat gtagggcctg caggtgcaag gtgacagagg
     2881 tttggagtct ttgcgctaat ctcgtttgca aagctgatat caaagtccat tccgatctca
     2941 tgagcgatag ccggaaggtg aagcatactg tttgtggagc atccgagtgc catgtctact
     3001 gtcagggcat tgaggattgc ttcttttgtc atgatatctc ttggacggat gttctttctg
     3061 tacatttcca taacctgcat acctgcatgt tttgcaagac ggatacgttc ggaatataca
     3121 gcaggaatag ttccgtttcc tttcagtccc ataccaagaa cctctgtcag acagttcatg
     3181 gagtttgctg tgtacatacc ggaacaggat ccgcatgtag gacatgtttt catttcacat
     3241 tctgtcaggc cgtcctcatc aagcttgcct gctgcgtaag cacctactgc ctcgaacata
     3301 ctggaaagac ttgtcttgtg tccgttcaga tgtccggcaa gcattgggcc gccgcttaca
     3361 aatacagtag gaacattcag tctggctgct gccatcagaa gtccgggtac gttcttgtca
     3421 cagtttggaa tcataaccag tgcatcaaac tgatgtgcca ttgccatggc ttctgtggaa
     3481 tctgcgatca ggtctctggt aaccagagaa tatttcattc caacgtgtcc cattgcaata
     3541 ccgtcgcaga ctgcgattgc cgggaacata acaggtgtac cgcctgccat tgccacacca
     3601 agcttaactg cctgtgtgat cttgtcaagg ttcatatgac ccggtacaat ttcattgtaa
     3661 gaacttacga tacctaccag aggtctgtcc atttcttctt ttgtcattcc aagagcatta
     3721 aacagggaac ggtgaggtgc ctgctgtgtg cctgttttta ctgcatcact tctcattgtt
     3781 ttatttcctc ttttcttact gttttattta tttttaatga ttcaaccgaa attcctgact
     3841 ccgtaatctg cctgcgccgg ctgaatcctc ttaatatcaa ttcttacaga gctgctgcga
     3901 tcagatcgcc catctctttt gttcctacaa gtttgcatcc ctctgacata atatcacctg
     3961 tgcggtatcc ctctgtcagg actttctgca ctgctgcttc cactgcatct gcttctttat
     4021 ccatgtcaag ggagaagcgc agcatcattg ctgcggaaag gatggttgcg atagggtttg
     4081 ccttatcctg tcctgcaata tcaggtgcag aaccatggct tggctcatag agaccgaatt
     4141 ttgtttcatt taagcttgca gaagaaagca ttccgatgga gcctgttacc atacttgcct
     4201 catctgaaag gatatctcca aacatattct ctgtcaggat aacatcaaac tgtttcggat
     4261 cacgtacaag ctgcattgcg cagttgtcaa ccagcatgtg ctctaaggta acatccggat
     4321 aatctttggc aacttcctct accacttttc tccagagtct ggaagaatcc agaacatttg
     4381 ccttatctac gcttgttact ttatttcttc tcttacgtgc gatctcaaat gctttgatgg
     4441 caatacggcg gatttcgttt tcattatagg aaagtgtatc aatcgctttc ttcacaccat
     4501 tctcttcaat agtctgacgt tctccgaaat acagaccgcc tgtaagctca cgtacaatga
     4561 tcatgtcaaa tccgtctccg atgatctcat cgcggagagg gcaggctttt ctcagctcat
     4621 tgtaaaggta agccggtctt aagtttgcaa aaagatttaa tgccttacgg attgcaagaa
     4681 gtcctgcttc cgggcgtttg gacggctcaa gtttatacca tggagaagtt tttgcatctc
     4741 cgccaataga gcccatcagt acggcgtctg atgatttggc agtggcaatt gcctcatcag
     4801 taaggggtac gccgtgtaca tcgatggatg cgccgcctaa cagaacttct gaataggaaa
     4861 agctgtgtcc atatttctcg cataccttgt ccagtacttt ctttgcttct cttacgattt
     4921 ccggtccgat tccgtcgccg gggatcaatg caatcttata atccataata atttcctcca
     4981 aaaatactct aattgcgtaa ttgttattat aataacgcac tttccgacag atttcaacct
     5041 attaaagtga aaaaatacaa aagtgctgtt ttccggagat tttactgtaa aaataaaaaa
     5101 acagaaccac agccatcact gactataggt tctgcttttt tcatatctct ttcattattc
     5161 ggcagcgctt ccggctttct caacttcagc gattgcctgt tttctcattg gaatacggca
     5221 gtttttgttg ttaccgaatt ctacgatcac gtcttcttct gtcatatcaa tgacaactcc
     5281 ataaaagccg ccggtagtaa caatgctgtc gccaacctcc atgtcattta acattgcctg
     5341 aagtctcttc tgctcttttt tctgagggcg aagcattaag aagtacataa ttccgaacag
     5401 tactaccatc cagacaatag cgccaaccat acccattccg cttgatgcgt ccattttgat
     5461 tcctcctgta acttttcctg ttattctgca tatttgcagt ccatcatgta ttcacagacc
     5521 gtcctgacgg ctgctcatac tgaagagctg ctttgcgatc cacttataat ctccgttacc
     5581 ttctgtatga aatcttgttt tcatgcagaa caatctgatt aaagcgtcac tacacatcat
     5641 acacaaaaaa gcgctttact tcaagagttt ttggcatatt taataattat tttatatata
     5701 gattatcttt ttgagtttat tttgccctct tcaaagcctt ccaaccgcat tttcttatat
     5761 tctgcgaagt ttcctgcatc aagagcatct cttatctctt ccatcatatg attatagaaa
     5821 tacagattgt gaagtacaca gagacgcatt cccagcattt cctttgcttt cagaagatga
     5881 cggatatagg ctctgctgta atgctggcat gcaggacact gacagccttc ttcgatagga
     5941 cgtgtgtcca gttcatattt tgcattgaac agattcatct ttccatgatt ggtatataca
     6001 tgtccatggc ggccgttacg gcttggatat acgcagtcaa agaagtcaat tcctctctca
     6061 acaccttcca gaatatttgc cggtgttccc acacccatca ggtaagtagg tttattctga
     6121 ggaagatagg ggactaccgc atccaggatc ctgtacatct cttcatgggt ttctccaact
     6181 gccagaccgc cgacagcata gccatccaga tccatttcag agatcgcttt ggcatgctca
     6241 atgcggatat cttcataaac agcaccctgg ttgattccaa acagaagctg ttctttgtta
     6301 atggtatccg gcagactgtt cagtctcgcc atttctgctt tacagcgggc aagccatctt
     6361 gtggtcctgt ctacagattt ctgcacataa tccctgtcag ccacactgct gggacattca
     6421 tcaaatgcca tggcaatggt ggaggcaaga ttggactgaa tctgcatact ctcttccggt
     6481 cccataaaga tcttatgccc gtcaatatgg gaattaaaat aaaccccctc ttctttgatc
     6541 tttctcagct ttgcaaggga aaatacctgg aatccgcctg agtctgtaag gatcggtttg
     6601 tcccatacca taaatttatg aaggccgcct aactgcttta ctattttatc acccggacgc
     6661 acatgaagat gataagtatt tgataattct acctgtgttc cgatctgctg taaatccatg
     6721 gtggatacag cgcctttaat cgcaccgatc gttcccacat tcataaaaac aggagtctgg
     6781 atcgtaccat gcactgtatg aaactctgca cgcttggcac ggccttctgt tttaagaagt
     6841 ttatattctg ccattttttc tctcctcttg ataaaaatca ctttttctat tatatcccga
     6901 aatagctgaa ttttcaactg caaataaggt aatcattggt aaactttcat attgtctttt
     6961 ccagaccatt agcgtataat attacggaat attccatatc tggaaacaga tatttaatag
     7021 gaaagaacag gatagatttt tactgtttac ttcgtgtccg gcaacacgct ttgcatgata
     7081 tcagcagcaa acagtaagga aaatgttact gttcactccg ttctcagtaa cgtagccaaa
     7141 attcattcca gattgcctgt ggcaatggaa ttttggcttg tatgtctcgg gattttggca
     7201 tattcatgcc aaaacacctc gcgggatagt ggtgtgtgaa cagtaacagg aaaatttcaa
     7261 ttttgtttat atacaatacg aggaggcttg aatttacttt atgaattaca aaacacttgg
     7321 aattgacatt ggttccacta ctgtaaagat cgcgatctta gatgagaatg aaaatctcat
     7381 tttcgcggat tacaagcgtc attttgcgaa cattcaggaa acccttgcag accttcttca
     7441 ggaggccttt gaccagtatg gcgagatgac tctccatcct gtgatcacag gttccggcgg
     7501 tctgaccctt gccaaccatc tgggcgttcc ttttacccag gaggttattg cagtttctac
     7561 ttctctgcag aagctggcac ctaagacaga tgttgccatc gagcttggcg gtgaggatgc
     7621 caagatcatt tatttcgaaa acggaaacgt agaacagcgt atgaacggta tctgtgcagg
     7681 tggcaccggt tctttcatcg accagatggc ttctcttctc cagacagatg ccacaggtct
     7741 gaatgaatat gccaaagatt acaaagcgct ctacccgatt gctgcacgct gcggtgtttt
     7801 cgccaaaacg gatatccagc cgctgatcaa tgacggtgca accaaaccag atctgtcagc
     7861 ttctattttc caggcagttg taaaccagac catctccggt cttgcctgcg gaaaacccat
     7921 ccgtggacat gttgcattcc tgggtggtcc gcttcacttc ctgtccgaac tgagagaatc
     7981 ctttatccgt actttgaagc tggatgggga acacaccatc attccggaga actcccatct
     8041 ttttgcagcc atcggttctg cattaaatgc caaagaagac aactccattt ccctgacaga
     8101 aatgaaagac agactccgca attccattaa gctggatttt gaagtagaac gtatggaacc
     8161 acttttcgct tctcaggaag aatacgatgc atttgcaaaa cgtcagagtt cctacaaagt
     8221 aaaaacagga gatctggcta catataaagg aaactgctat ctgggtattg atgcaggttc
     8281 caccacaacc aaaactgcac tggtaggcga agatggaaca cttctctatt ccttttacag
     8341 tagcaacaac ggaaacccgt taaaaactac catccgttct attaaagaaa tctatgaact
     8401 gcttcccaaa gacgcaaaga tcgcttattc ctgttctaca ggttacggcg aggctctgct
     8461 caaagcggcc ctgctcctgg atgagggcga ggttgagacc gtatcccatt actatgcagc
     8521 tgcattcttt gacccagagg tagactgtat cctggatatc ggcggacagg atatgaaatg
     8581 tatcaagatc cgcaacaaga ccgttgacag cgtacagtta aatgaagcat gctcctccgg
     8641 atgcggttcc tttattgaaa cctttgccaa atccctgaat tatacagtac aggatttcgc
     8701 aaaagctgct gtttttgcac agcatcctat agatcttggt accagatgta ctgttttcat
     8761 gaattccaag gtaaagcagg cgcagaaaga gggagctgag gtttccgata tttccgcagg
     8821 tcttgcttac tctgttatca aaaatgctct gtataaggtt atcaaggttt ctgacgcttc
     8881 cgaacttggc aagcacatcg ttgtacaggg tggtaccttc tacaatgatg cggttcttcg
     8941 aagcttcgaa aagattgcag gctgcgaagc catccgtccg gatatcgccg gaatcatggg
     9001 tgccttcggt gctgcactga ttgcccgtga acgccatcag gaaggcgcag aaacgactat
     9061 gctctccatt gataagatca acgagctgaa atatacaact tctatggcaa actgtcgtgg
     9121 atgtaccaat aactgccgtc tgactatcaa caaattctcc ggcggccgcc agtatgtaag
     9181 cggtaaccgc tgtgaacgcg gtatcggtaa ggaaaagaac aaagatcata ttccgaatct
     9241 ttatgaatac aaatataaac gtattttctc ctacacaccg cttactgctg ataaggcaac
     9301 gcgaggtaaa gtaggtatcc cgcgtgttct gaatatgttt gagaattatc ctttctggta
     9361 tactttcttt acagaactga agtatgaggt tgtgctctct cctacttcca ccagaaagat
     9421 ttatgagttg ggtattgaat ccattccaag tgaatccgaa tgctaccctg ccaagctcgc
     9481 acatggccat gtaacctggc tgatccgcaa tggtgtgaaa tttattttct acccttgtat
     9541 tccatatgaa cgtaacgagt tcccggatgc agtcaatcac tataactgcc cgatcgttac
     9601 ctcttatgcc gaaaatatca aaaataacgt agacgaatta aatgatccgt ccattacctt
     9661 ccgcaatccg ttccttgcat ttacttctga ggaaattctg gcaaatcgtc tggtagagga
     9721 atttaaggat atcccggcag aagaagtcaa agctgctgtg cataagggct gggaggaaat
     9781 ggctgctgca cgccgcgatg tacagaaaaa aggggaagaa accctgaaat atctggaaga
     9841 tacaggacgc catggtattg tccttgcagg acgcccatac catattgacc cggaaatcca
     9901 tcatggtatc ccggatctga tcaacagcta tggtattgcc gtacttaccg aggattccat
     9961 ctctcatctg gcacctgtgg aacgcccgat ccgcgttaat gaccagtgga tgtaccactc
    10021 cagactgtat gctgctgcaa actatgtaaa gacacgcgat gacctggatc tgatccagct
    10081 caactctttt ggatgtggtc tggatgcagt tactactgac gaggtttatg aaatccttga
    10141 cggaagtgac aaaatctata cctgcttaaa gattgacgag gtaaataacc ttggtgctgc
    10201 aagaatccgt atccgttccc tgatcgcagc gatccgtgcg aagaaggcac agggacagaa
    10261 acgtactgtc aaacctgctt ctattgataa agtatccttt acaaaggaaa tgagaaagga
    10321 ctataccatc ctctgcccgc agatgtcacc gttccatttc agcctcctgc aggcagcatt
    10381 caattcctgc ggatacaacc tggaggtgct tccgaatgac aataagcatg cagtggatgt
    10441 tggtctgaag tatgtaaaca atgacgcctg ctatccgtct ctgatcgttg tgggacagat
    10501 catggatgct ctgctttccg gtaaatatga cctgaacaaa acggccgttg tcatgtcaca
    10561 gacaggtggc ggatgtcgtg cttccaacta tatcgcattt atacgacgcg cattaaagaa
    10621 agccggtatg gaacagattc cggttatctc tgttaactta agcggtctgg aaagcaatcc
    10681 cggattcaaa cttacgcttc cattagtgaa gaaagttgct tatggtgccg tattcggaga
    10741 tatcctgatg aaatgcgtat atcgtatgcg tccttatgaa ctggaagagg gaatcgtaaa
    10801 caggaaacat aaaatctggg aacagcgtgt gatctctttc ttaagcggaa gcagtatcag
    10861 ccacagccag tttaagaaaa tgtgccgcga aatggttcac gaatttgata ccattccgat
    10921 cagtgatgtg aaaaagcctc gtgtcggcat cgtaggtgag atccttgtca agttcctgcc
    10981 tgctgcaaat aatcatctgg cagagcttct ggaatctgaa ggcgctgagg cagttgtacc
    11041 ggatctgatc gatttcatgt gctactgctt ctataatcag aacttcaagg tagaaaatct
    11101 tggattcaag aagtccaagg caaccatggc aaactgggga atcaaagcaa tcgaatgggt
    11161 gagaaagcct gcaagcgaag ctcttgcaca gagccgccat tttgcaccgc ctgctgatat
    11221 cagaaatctg gcaaaaatgg catctccgat cgtttccacc ggaaaccaga caggtgaggg
    11281 atggttcctg acaggtgaga tgatggaact gatccatgga gatgttccga atattgtttg
    11341 tatccagcct ttcggatgtc tgccgaacca cattgtaggt aagggtgtta tcaaagagat
    11401 ccgcagagaa tatccgacag ccaatattgt agccatcgac tatgatccgg gtgcaagtga
    11461 agttaaccag ctcaaccgaa tcaaactgat gctctccaca gctcagaaaa acctgaaaaa
    11521 agcagaagaa aaaatgcata aataataccg taatggatat attgcaatgt attttacctt
    11581 gcaatatatc cgccttagag cgtatttgaa aaatcattcc cgcaatctac atatcctgct
    11641 ttgcgaaaag catttttcaa acgcgctcaa aaaagagtta tatttcagaa attttaaatg
    11701 tgtttctatt tcagaaatac atttaaacca tgaaatataa ctcttttatt ttttataact
    11761 tctgttttta taacttctgt tttttaatta ttctgccaga acggaagttt ctctgcaatc
    11821 cttatcagat agcttccacc cggaattctt ctaagctgtg attctgacgg cttgctgatg
    11881 atcaggtaag caaacagata aacaaccgca gcaacaggaa tggaaacgat cagacaaatg
    11941 aaattggatt ttacaaaaat gttcagtcca tagcagatac agcctgcaac aattcccatg
    12001 ggaacagatg caagaacagg atacagatat ccttctttcc atggattctt atactgcaga
    12061 tatttcttca tggctctgtc atttaacaca catacaacca cagaatagat caccattgcg
    12121 atcagcagtg cataaactcc aaggtttgta gtaaacagca gcactaccac taccacaata
    12181 tccacaacca gtgcgattgc agccgtaatc accggaatcc tctgctgtcc gattgcctgc
    12241 agaactccat tggaaatatt tgacattcca ttgagcagga tcgaaaaaga accaaggatc
    12301 agcagattgg ctgccagtcc tgtggaattt ccgtaaagca aaaatacaat cggctgtgca
    12361 agcactgcca gtcccattgc acatggggcg gaaactacca tagaaagctg tacggtctgg
    12421 tcaatgcact ctctggtcgc ttcaatatct tcggtggcat acaatgcaga aacttccgga
    12481 atcatggaag taggtgccgt actggacagg gtcagaggaa tattaataat tgtcataaag
    12541 taagtggcat actctgcata taaaataccg atctgtgccg catctccacc tcttcttccc
    12601 agaatatccg agaaaagata cccattgata taagcattta cattataaac aaaggcgctg
    12661 agaataatcg gcgaaacaac caggatgatc acacgaaaaa tctctttgta ggactcttcc
    12721 tgatgtctgt gatctctctc tacccggtgc agaatttttc tgcggtttac accatacacc
    12781 agaagcatga atgccaatgc agtcaccact ccggctccgg ttcctactgt ggaacctgct
    12841 gccccccatt ttgcaatgct gttctctgtt ccatctgaga atgcattgat gaatccccag
    12901 gctgccagaa gactgactgc cgcattaaat acctgctcaa tgatctggga gatagatgtt
    12961 ggcatcatat ttctgtatgc ctgaaaatat cctctgaata ccccaagaat accggacaaa
    13021 aaaatcgtcg gagccaggat ctgaagtgcc ggaattgcat ccttctgatt ctgagggatg
    13081 atcagccctg ctccaaagag gcagaataaa ccgaccactc cgccaatcac catggcatag
    13141 atcatggcac ccttaaagaa cttatgtgca tttctgtaat ccttcagagc aatacgctcg
    13201 gagatcagct tggataccgc ctgtggaata ctaaaggatg cgatcatcag aaggatcata
    13261 taggcattct gtgcaagact tgtatagccc attccaaggc ttccgataat attggaaagg
    13321 ggactcttgt acagaagacc gatcaccttg gagatcatag ctgcaatcat cagaaaggat
    13381 gcatttttta ctaaattgtt tttctgattc atgttatcac tgtgtgtctt ttacctgact
    13441 acacattacc tcttttctta tatattttct atctgccagt cgattggttc cagaccattg
    13501 gcaacaagaa attcgtttgt tttactgaaa tgtttacatc cgaaaaatcc cctgtaagca
    13561 gacagaggac ttggatgagg tgcctccagg atcagatgct tcggattatt caacatggat
    13621 tttttcatct gcgccggacg tccccagagc agaaatacaa taggacggtc ctgctcattc
    13681 agaacctgga tcgcagcatc cgtaaactgc tcccagccga tccccctgtg tgaatttgcc
    13741 tgatgagcac gtacagtcag aactgtgttc agaagaagca ccccctgctt tgcccacttc
    13801 tccagataac cattattggg gatataacat ccgcaatcat catgaagctc ctgataaata
    13861 ttcaccagag acggtggcgt ctccactcct ctctttacgg aaaaacaaag cccatgagcc
    13921 tgcccgtcat tatgataggg atcctgaccc agaatcacta ccttcacttc gtttaacggc
    13981 gtaaaatgaa atgcattaaa caaatcatcc gcaggaggaa aaatcttcct ggtctgatat
    14041 tctgtcatca ccgttttata taatttcgca taatacggct ggtgaaactc ccccttcagg
    14101 gcttccagcc agtcacctga aattgctgac ataccttatc cttcacctct tatatttttc
    14161 gtggtcatcg tctgacagaa attcccctgt cagacagata atccttcacc tgagaaatct
    14221 ccagttcttt ataatggaac aaagacgcag ccagtgcagc atctgctccc ccttcggtca
    14281 gtgcatcata aaaatgctcc agtgtacctg caccgcctga tgcgatcaca ggaatggaga
    14341 cagcatcagc gattgctctg gtaagagcca gatcatatcc tgcttttgta ccgtcacagt
    14401 ccatacttgt gagaagaatt tcccctgcgc ccaaagcttc cactttcttt gcccactcta
    14461 tggcatcaat ccctgtatcc agtcttccgc catgtttgta aatattccat ccgccgtctt
    14521 ctctgcgctt ggcatcaata gccacaacta cgcactggct tccaaacttg tcagccgcct
    14581 cactgatcag ttccggtctg tcaattgctg cagaatttac ggaaatctta tctgctcctt
    14641 ctctcagcag tttcttgaaa tcatctacag tacggatacc gccgcctact gtaaacggga
    14701 taaatacatt ggcagcaacc cgtcttacca tgtcaactac cgtatctctc tgttcgcagg
    14761 atgctgtaat atcgagaaac accagttcat ctgctcctgc tgcatcatag gctttggcaa
    14821 tctccaccgg atcacccgca tcgcgaagct gcacaaaatt tacgcccttt accacacgtc
    14881 cgttatttac atccaggcag ggaataattc tctttgtaaa catcttattt tccctccttc
    14941 tcagtattgc cgtcttttcc cacagcagca aaattttcaa gtatcttcag tccccatttg
    15001 ctgctctttt ccggatggaa ctggcaggca aatacattgt ccttttctac ggaagcatga
    15061 atacaggtgc tgtattctgt agtagccttt acaatctcag gctcctctgc ctgcagataa
    15121 taggaatgca caaaatatac ataggtctgt tccgggattc cctgaaacag tctgccatta
    15181 ttctgaaaat gcagggaatt ccatcccata tgtggaatct taagcccggg cgcaggagga
    15241 atcttaacaa ttttcccttt caggattcca aggccttcca cccccggtgt ctcctcgctg
    15301 ctttcaaaaa ggagctgaag tcccaggcag attccaagaa atggcgtctt cttctctaca
    15361 atctcatgga tcacaggtac aagtccgtat gtatgaagat tctccatcgc ctgtccaaag
    15421 cttcccacgc ccggcaggat tactttatcc gcatttaaca aagtctgcgg atcgcgggtt
    15481 actgttgttt cttccccaag ataatgaagt gctttttcta cacttttaat atttccggca
    15541 tcatagtcaa ttattgcaat catgttatcc tcctgatgtc attatctgtt ttcctcatta
    15601 tggtaatcca aaggttttcc ggatcacatg tcagaccgga ataaaatatc cgatcaaaac
    15661 gctccaatac agtataaccc aaaaacagac agttgcaaag tgctttcttt gcttctgtct
    15721 gtttttattc cggtcatact accggttact gttcactccg ttcacaatac ccggatatct
    15781 tatcactgcc tgcaatccag agtgaaccag aactccacgc cattatcata attgcatacc
    15841 ccatatttct ggttcatact ctcaatgatt gccttaacaa ttgaaagtcc gataccactt
    15901 ccgccatatt ctcttgtccg ggccttatct actttgtaga atttattcca gagatttggg
    15961 atatcctctt ctggaatcgg agtacctgta ttaaatacgg ttactttcac acagtcctct
    16021 tcctgaagaa ccttaatttc tacttttcgt tctccgtcca gatggttcag tgcattgctt
    16081 gtataattgg tcacaacctc ttcaatctta aactcatccg cccatacata tacaggttct
    16141 gtttcttcaa aaatcacagt tgcttctttc tgttcgatca taatatgcat agaaccaagt
    16201 acacccctga tcagagatac aatgtcaaat ctttccatca ccggggcatc tttaccggac
    16261 tccagctgat tcagcgtcag caggtttttg accagcttgt tcatctttga agcctcatcc
    16321 ataataactt cacagtaaaa ttccctgctt tccggatcat cggaaatatt ttcattcagc
    16381 ccctctgcat atccctggat caatgcaata ggagttttca gctcatgaga aacattatca
    16441 agaaattcct tacgcatctc atcaatttta atcttatctt ctatgtcttt ctgaagcttg
    16501 ttattagccg atttcaactc tgagatcgtg ctctcaagtt ttctggacat tttgttaaag
    16561 ttatcgccaa gtacatcaat ctcattacct gccctgcttt gatatctggc atcaaaatcc
    16621 agatcagaca tcttctctga taatttggtc agttcactga tcgggcgggt aatacgattt
    16681 gtcatcacaa gaatcacaat accgctgacc acaattatga ttattcctac aatgaagtaa
    16741 aaactgttgg aaatagatgc actttcctta atactttcca gaggagaacg aatcaggaaa
    16801 tagtaaccat tatcaaactg tccccagcat tccacatatt ccatgcctgc aaagcgatca
    16861 tgcacctgcc acatggtaca ggtatctgtc tttttgagca cacgactgtg ctgcatatcc
    16921 tgatccagat tattaatata cccaaacagc ttactgcgga gcatttttgc catattattc
    16981 tctccccagt aataataacc gctgttttcc tcatttacta tgatccaggt aaggttattt
    17041 ctggaactgc tcctctcaat ctcatccgaa atctcatctg ttgccccttt tttgtcctct
    17101 tctatatctg tatcatactg caggatgtca tccagattca tctgagacaa cacttctttt
    17161 gcctcctcca gcacttctac ttttttggat acataatatt tttcaagaaa aagaccattg
    17221 atcagagtaa tggtaaagat cgaaagtagt aacagacata taaacactac tgaaatctga
    17281 tgttgcagag tatgaaattt tttatctgtt tttccgtttc ctgtcattcg tctacctcaa
    17341 acttgtatcc cataccccat acagtcttta tatattcacc tttatctccc attttacttc
    17401 tgagcttctt aacatgggta tcaatcgtac gggcatctcc aaagtagtca taattccata
    17461 cagaattcag gatcttttct ctggaaagtg cgattccctg attctccaga aaatatgtca
    17521 gaagttcaaa ttccttaaag ctcagttcca taggcttacc atccacagta gccagatgtg
    17581 ctgctttatc tataacaatg ccgcctgctg aaatcacatc ttccggatta ttctgacctg
    17641 tacgtctcag aattgcctcc actcttgcaa caaggatttt cggactgaat ggtttggaga
    17701 tgtattcatc tacccccaga tcaaatccaa gaagctcatc tctctcatca cttcttgcag
    17761 tcagcataat gatcggaact tttgagttct tgcgaatctc acggcaaact tcccatccat
    17821 ccatcttcgg catcatgaca tccagaatga tcagtgcgat gtccttctcc tcataaaaga
    17881 tatccatggc ttcttcacca ttaccggctt ccagtacctg gaaattcttc tttgtcagga
    17941 aatcctttac cagctttctc atgcggctct catcatccac caccaggatt tttaatgtat
    18001 ccatttgatc ccctccgttt ttcttcatta ttttccgaaa cagtttttac tttttattta
    18061 tactgttttc cgagtattgt taaaatccac gactgttcag cgcctttaca gccacagcgc
    18121 aaaatccggg aaaatcgccc tcagcaacag attttatctt tcatatggtt actatagcag
    18181 agatttatgt aagatttgtg aacatatgac agaaaaatta taagtattgc tgttcacaac
    18241 accaaatagc cgttactgtt cactccgttc tcagtaacgt agccaaaatt cattccaaat
    18301 tgcctgcggc aatggaattt tggctt
//
