LOCUS       c00084_gnlPro..        12166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMLIJEHL_84.
ACCESSION   c00084_gnlPro..
VERSION     c00084_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 01:02:09
            Original ID  :: gnl|Prokka|BMLIJEHL_84
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12166
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12166
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:12164]"
                     /cutoff="10000"
                     /detection_rule="(CdhC and CdhD and minimum(8, [CbiA,
                     FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane,
                     Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter,
                     THF_DHG_CYH, THF_DHG_CYH_C]))"
                     /neighbourhood="10000"
                     /product="Acetyl-CoA_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..12164
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(CdhC and CdhD and minimum(8, [CbiA,
                     FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane,
                     Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter,
                     THF_DHG_CYH, THF_DHG_CYH_C]))"
                     /neighbourhood="10000"
                     /product="Acetyl-CoA_pathway"
                     /protocluster_number="1"
     cand_cluster    1..12166
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(CdhC and CdhD and minimum(8, [CbiA,
                     FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane,
                     Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter,
                     THF_DHG_CYH, THF_DHG_CYH_C]))"
                     /kind="single"
                     /product="Acetyl-CoA_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12166
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Acetyl-CoA_pathway"
                     /region_number="1"
                     /rules="(CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS,
                     FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind,
                     Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH,
                     THF_DHG_CYH_C]))"
                     /tool="gutsmash"
     CDS             complement(2..295)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: THF_DHG_CYH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_1"
                     /sec_met_domain="THF_DHG_CYH (E-value: 6.3e-27, bitscore:
                     83.7, seeds: 1211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKQLLGKEVTAALNEKIKANVAELQGKGVNPTLCIIRVGENPSD
                     ISYERGATKRCETLGVACEKILLPEDVSQEELLATIDKVNKDDSIHGVLLFRP"
     CDS             complement(468..1097)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: FTCD_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_2"
                     /sec_met_domain="FTCD_C (E-value: 4.1e-73, bitscore: 234.4,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFSTSTCTEFVEVLASKAPVPGGGGASALVGAVGTALGNMVGSL
                     TVGKKKYADVEDEMYELKAKCDQLQKDFLRLIERDAEVFEPLSKAYGMPKETEEEKAEK
                     ARVMEIVLKDACSVPMEIMEKCCEAIELIVEFGAKGSKLAISDAGVGAAFCKAALQGAS
                     LNVYINTKSMADREYAEELNRKADAMLEKYTKIADDTFNSVLGRLK"
     CDS             complement(1190..1858)
                     /locus_tag="ctg84_3"
                     /transl_table=11
                     /translation="MAFSLNDLNYEKDSKERMPWEHYTQEFATADPKEIASRLSIPYDE
                     EAKKLTLTFLGTQYQITWPDFEVTHTPDDKGFYPLENMIYARILTIRFLLNGVKSESSG
                     KFKTYREMPWGEVYLRQFDGRCIKRLAFSYGNRPGDFRAIMEHISAIPVKHGDIAYEVE
                     IFPEYKIQMILWEGDEEFPPSSQILFSDNFPVSFQAEDMAVMGDVIIGSLKAYLKCVQK
                     "
     CDS             complement(1965..3905)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: Fer2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: RACo_C_ter"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_4"
                     /sec_met_domain="Fer2 (E-value: 3.4e-14, bitscore: 42.1,
                     seeds: 206, tool: rule-based-clusters)"
                     /sec_met_domain="RACo_C_ter (E-value: 3.9e-97, bitscore:
                     313.7, seeds: 142, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKVTFSFEDGSMVETFANAGDNLLEVARSANVAIDAPCSGNGAC
                     GKCRVQLKSGELESKKTLHISDEEYQAGWRLSCCSKISADVNVLVPDIASAYKSRMKVA
                     DLSSKEEIAIFENAKSDIQLAGIELKNSLEVVDVLMDVPSLDDTMPDNERLTRALRKYL
                     NINRVRIPYVVLKKLPDVLRENNFAVKCVIRATSDDMYVYDIFGKDEDVVIGGLAIDIG
                     TTTVSAVLINMENGEILAKSSAGNGQIRFGADVINRIVESQKPGGQKKLQDAVIKETIN
                     PMIHEMCKSAKFPKDHIYRMCVASNTTMNHLFAGINADPLRTEPYIPAFFKTNSLFASD
                     VGVDINKDAHIIMAPNIGSYVGGDITAGTLVSQIWNRPEFSLFIDLGTNGELVFGNSDF
                     MMSCACSAGPAFEGGDISCGMRATDGAIEACTIDKETMEPTYKIVGDPGTKPVGLCGSG
                     IIDVISELYICGIINPKGKFIREGKRIKHDKYGMGSYILAFEEEAGSVKDVEITEVDID
                     NFIRAKGAIFSAIRTMLTSLDFDVSMIDDVYVAGGIGSGINMQNAVNIGMFPDIPIEKF
                     HYIGNSSLTGAYLMLLSTPAEKKTYELAANMTYMELSTVPIYMDEFVGACFIPHTDTSM
                     FPTVMEEVQNR"
     CDS             complement(4039..4824)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: Pterin_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_5"
                     /sec_met_domain="Pterin_bind (E-value: 9.1e-28, bitscore:
                     86.9, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFVTIGERLSTTAPAVNKAFTERDPEPIIKRAKQQLDAGATYL
                     DVNIGPAENDGEDLMKWAVQLLQSEFDNVPLALDTTNKKAIEAGISVYNRAKGKPIVNS
                     ADAGDRITNIDLAAANDAICIALCSSGMVAADNDERMMHCQNMLERGMSLGMEAEDLWF
                     DPLFLVVKGMQDKQMEVLEAIKMFSDMGLNSTGGLSNNSNGMPKHIRPIMDSALVAMAM
                     MNGLTSAIVNPNDLRLMETIKSCDVFKGNTLYADSYLEI"
     CDS             complement(4926..6284)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: CdhD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_6"
                     /sec_met_domain="FeS (E-value: 9.2e-14, bitscore: 40.4,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="CdhD (E-value: 4.7e-79, bitscore: 255.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALNGIQIFKLTPKKNCKECGCPTCMAFSMKVAQGAMKIEQCPHM
                     SDEALASLSEATAPPMKTIKIGTGAEEHTLGGETVLFRHEKTFVSKPRYAVALCTCMDD
                     ATVEAKLAEIPKVDYDRIGERMYAELVYVNCGEGADAAKYTALVEKAAGLGRTLVLECK
                     DPEIAKAALAVCKDSKPVLNGADASNYEAMNAVATEAGVVLGVSGKDLNELYDTTAALE
                     KLGNKNLVLDTTGADIKETFANTVQVRRAALKDQDRTFGYPSIVNLVKIAKGDLHLQAA
                     LASMFTMKYGSIIVMEQMTYAEALPLYGLRQNVFTDPQKPMKVEPGIYPLNGADENAVV
                     VTTVDFALTYFVVSGELERSGVPLNLVINDAGGLSVLTSWAAGKFSGNSISAYIKENVE
                     PKVKSRKLIIPGKVAVLKGDLEAKLPGWEIIVGPREAVQLVKFLKDMQADGQI"
     CDS             complement(6307..7251)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: CdhD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_7"
                     /sec_met_domain="CdhD (E-value: 1.7e-36, bitscore: 115.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFNQKLQKFNAKINTVTIGSGDKTVTIGGDSTYPFYSFDAPSEN
                     TPKIGVEISDMGLENVVSEGIKAYYDGASTIGEMAKKAAAMEGADFVALILEGGDPNGV
                     NKSVDELIAVVKDVADSIDAPLVVEGCKNVEKDAELLPKVAEALQGRNVLILSEKEENY
                     KAIGAAAGLAYDQIVGAESAVDINLAKQLNVVTTQLGVNAQKIVMNIGSAAAGYGYEYV
                     VSTMDRIKGAALSQNDNMLQMPIITPVSAETWGVKEATASEADMPEWGPEEERGIDMEV
                     MTAAADLAAGSDAVILRHPEAVATISRMIKALA"
     CDS             complement(7685..9811)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: CdhC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_8"
                     /sec_met_domain="CdhC (E-value: 1.7e-69, bitscore: 222.1,
                     seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTLFESVFAGNDAVYGLTEGAINQAIEKYGADKAVSFPDTAYSLP
                     CYYAVTGTKVGTLAELKDALAVVKTLMTREKRTNDVFMSGVATALCAEFIEVLKYIDGA
                     VPYEAPCYGHLADAVIRELGVPLVTGDIPGVAVILGKAPSAQEAADLVKSYQSQGILIT
                     LVGDVIDQLEEVGYKTGANVRVIPLGKDVTAVIHVVSVALRAALIFGNVKPGDAATLMD
                     YTMKRVPAFVNAFAPLNDVIVACGAGAIALGFPVITNQEDVARVPKSLICQKDISKWNA
                     TSLEARDIKIKITNIDIPVAFASAFEGEIIRRKDMQVEFDGSRVDCAELVHTCDASEVE
                     DHKITVVGPEVDDMELGSKNSIAYVVKVAGKNMQPDFEPVIERKFHNYINCIEGVYHTG
                     QRDMQRIRISKDAFAAGFKIKHIGEVLYTQVKNEFDAVVDKCEVTIYTDPAECTRIRHE
                     VAIPIFEKRDDRLNTLTDESVDVYYSCILCQAFSPSHVCVVTPERLGLCGAVSWLDAKA
                     TNELDPNGPCQVITKERPIDENLGSYEDVDEAVKKLSQGALEHVTLYSIMQDPMTSCGC
                     FECICGIEPFSNGVVIANREYAGMTPLGMTFSEMASMTGGGVQTPGFMGHGKHFISSKK
                     FMKAEGGIERIVWMPKELKEFVAERLNNTAKELYGIENFTDMIGDETIATDPETLVGFL
                     TEKGHPALALDPMM"
     CDS             complement(9838..10602)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: CbiA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_9"
                     /sec_met_domain="CbiA (E-value: 2e-21, bitscore: 65.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAVTGKGGVGKTTFAATLARLYAAEGRPVLAADVDPDANLGLA
                     LGFDEETLDSIVPISKMRKLVEERTGATAGNQFYHLNPKVDDIPEKYGKVCNGVRLLVL
                     GTVETGGGGCVCPEHVMLKRIINNLVLRREDVVILDMEAGLEHLGRGTTEGVDAFIVVI
                     EPGARSVQTYKNVKRLAKDLGVAQVKVVANKVRNEDDENFIRERIPQEDLLGMIHYNTE
                     VIDADRQGKSPYDFSKTVTDEIIKIKEKIDRQ"
     CDS             complement(10647..12164)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Acetyl-CoA_pathway: Prismane"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_10"
                     /sec_met_domain="Prismane (E-value: 3.7e-133, bitscore:
                     434.2, seeds: 159, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KEWGVETEGKDIYDLAHEMAETGLMEYGKPFGYQRFLDRMPAGQK
                     EKLIENEIAPRAIDREVSTSLHMAHMGCSSLPEALVKQSIRCGLADGWGGSMMGTEFSD
                     VLFGTPKPIDTEANLGVMVEENVNIVVHGHDPSLSEMICEYADSKEMIDYAKSVGAKGI
                     TVSGVCCTSNEVAMRRGVPMAGNFLQQENVVLTGACEAIVVDVQCIFPALGPLSKCFHT
                     KFITTSPIAQMPDAEFIRFNAETAGENAKAIVKMAIDNFKNRKPELVHIPQLKQKATVG
                     YSVEAIVKVLDGVTNSQVDETGTTKPLLECITSGVIRGAVAMVGCNNPKIRPDYAHIEL
                     MKKCIANDIVVIASGCSAQAAAKAGLMDKSAKDLCGAGLKRVCELADIPPVLHMGSCVD
                     ISRMMILAAELAKDAGLQINQLPVVGCAPEWMSEKAVSIGNYVVGTGIDTFLGVDPYVS
                     GSSEMGELLTEGTRKWTGAAYTVETDIEKLVDLMIERIEEKRTALGI"
ORIGIN
        1 gcggacggaa taataatacg ccgtgaatgc tgtcatcttt gtttacttta tcgattgttg
       61 caagaagttc ttcctgggaa acatcttccg gaagtaagat tttctcacat gcaacgccta
      121 aagtttcgca acgttttgtt gctcctcttt cataggagat atcgcttggg ttttcaccaa
      181 cacggatgat gcagagggta ggatttactc cttttccctg aagctctgct acgtttgctt
      241 tgattttctc gtttaatgct gctgttactt ctttacctaa taactgctta gccatttgtc
      301 gttccctccg aaattatacg ttattattct atactgtatc tgaatgattt cagcataacc
      361 gcctcataaa tcatatgcac tctgtaaaaa aatacatctc aataaataat gttacacttt
      421 attaaaagag acggaaaaca atacagaaat ttctatttta tttactatta tttcagtctg
      481 ccaagtacgc tgttaaatgt gtcatctgcg atctttgtat atttctcaag catcgcatct
      541 gcttttctgt ttaattcttc tgcatactct ctgtcagcca tggattttgt gttgatgtat
      601 acgttcaggc tggcaccctg taatgctgct ttacagaaag ctgcaccaac gcctgcatca
      661 ctgatggcaa gcttagagcc ttttgcaccg aattctacga tcagttcaat tgcttcacag
      721 catttctcca tgatctccat tggtacagag caggcatctt ttaatacgat ctccatgact
      781 ctggctttct cagctttctc ttcttctgtt tcctttggca ttccatatgc ctttgataat
      841 ggctcgaata cttctgcatc acgctcgatc agacgaagga aatccttctg taactgatcg
      901 cattttgctt ttaattcgta catttcgtct tcaacatccg catatttctt ttttcctaca
      961 gtaaggcttc ctaccatatt tccaagagca gttcctactg caccaactaa tgcagacgca
     1021 ccgccgccac ccggaaccgg agccttagat gccagaactt caacgaattc tgtacatgta
     1081 cttgttgaaa atcccatttt ttctccctct ttctttttgt ttatatttac ttatctgact
     1141 ctgatatccg cagattattc tgcaatctct ataatcctga tatcatttgt catttctgaa
     1201 cgcatttcag gtatgctttc agagaaccaa taatcacatc tcccataact gccatatcct
     1261 ctgcctggaa agagacaggg aagttgtcag aaaagagaat ctgtgaagac ggcggaaatt
     1321 cctcatcgcc ctcccagaga atcatctgta ttttatattc cggaaaaatt tctacttcat
     1381 aggcaatatc tccatgcttt acaggtatgg cactgatatg ctccatgatc gccctgaaat
     1441 ctcccggacg gttaccatag gaaaatgcca gacgtttgat acatctgccg tcaaactgtc
     1501 ttaaatatac ttctccccat ggcatctccc ggtatgtctt aaattttccg gaactctcag
     1561 acttcacacc gtttaaaaga aaacgaatcg tcaggatcct tgcatagatc atgttctcca
     1621 gtggataaaa acctttatca tccggagtat gtgttacttc aaaatccggc catgtaatct
     1681 gatactgtgt tccaagaaaa gttaaagtaa gtttttttgc ttcttcatcg taaggaatag
     1741 acagtctgga agcaatttcc ttcggatctg cagttgcaaa ctcctgagta taatgctccc
     1801 atggcattct ttccttactg tctttttcat aatttaagtc atttaagcta aacgccatat
     1861 aaatctccat aaacaggaca gatcaaaggg atctaaagat ccgtcctgtt atttttattt
     1921 ctctagatat tcataatttc tcatatagaa attactgaaa ttcatcagcg gttctgaacc
     1981 tcttccatta cagtcgggaa catacttgta tctgtatgag gaataaaaca tgcacctaca
     2041 aattcatcca tatagatcgg tactgtagaa agttccatat atgtcatatt tgcagcaagt
     2101 tcataagtct tcttctctgc cggtgttgac agaagcatca gatacgcacc tgtcagagaa
     2161 gagttaccaa tgtagtggaa tttctcgatc gggatatccg ggaacatacc gatgttgact
     2221 gcattctgca tgttgatacc gcttccgata ccgcctgcaa catacacatc atcgatcatg
     2281 ctcacatcga agtccagaga agtaagcatt gtacggattg ctgagaagat ggcacctttg
     2341 gcacggatga agttgtcaat atcaacttct gtaatctcaa catcctttac agaacctgcc
     2401 tcttcctcaa atgcaaggat atagctgccc attccgtatt tgtcatgttt aattctcttt
     2461 ccttcacgga taaatttacc cttggggttg atgattccgc agatataaag ttcactgatc
     2521 acatcgatga taccggatcc acataaacct acaggtttcg ttcccggatc acctacaatc
     2581 ttgtaggtag gctccatagt ctctttgtca atggtacatg cttcgatagc tccgtctgtg
     2641 gcacgcatac cacagctgat gtcaccaccc tcaaaggcag gacctgctga acatgcacag
     2701 ctcatcataa agtctgagtt tccaaataca agctctccat ttgtaccaag gtcgataaac
     2761 agtgagaatt cgggcctgtt ccaaatctgg ctgaccagag ttccggctgt gatatcgccg
     2821 cctacatagc ttccgatatt cggcgccata ataatatgag catctttatt gatatcaact
     2881 cccacatcgg aagcaaaaag ggaattggtc ttaaagaatg cagggatata aggctctgta
     2941 cgcaacggat ccgcattgat tcctgcaaac agatgattca tagttgtatt ggatgccaca
     3001 cacatcctgt agatatggtc tttgggaaat tttgcactct tgcacatttc gtggatcatt
     3061 ggattgatag tctccttgat caccgcatcc tgcaattttt tctgacctcc gggtttctgt
     3121 gattccacga ttcggtttat tacatctgca ccaaaacgga tctgtccgtt tccggcagaa
     3181 ctttttgcca gaatttctcc attttccata ttaatcagta cagcagaaac tgtagttgta
     3241 ccgatatcaa ttgccagacc tccgatgacc acatcctcgt ctttgccaaa tatatcatag
     3301 acatacatat cgtcagaagt agcgcggatc acacatttca ctgcaaaatt gttctctctc
     3361 agtacatcag ggagtttttt caggactaca tatggtatcc gtactctgtt gatatttaaa
     3421 tatttccgca atgcacgtgt caatctctca ttgtccggca tagtatcatc cagagaggga
     3481 acgtccatca gcacatccac aacctccaga ctatttttca gttcaatgcc tgccagctgt
     3541 atatcactct tggcattttc aaaaatggct atttcctctt tcgaacttaa atcagctact
     3601 ttcattctgc tcttataggc agatgcaata tcaggtacca gtacattgac gtccgcactg
     3661 atcttgctgc aacaagacag acgccatccc gcctgatatt cttcgtcaga aatatgtaat
     3721 gtctttttgc tttccagttc tccgctcttt aactggacac gacattttcc gcaggctccg
     3781 tttccggaac atggtgcatc aatagccaca ttggcacttc gtgcaacctc cagtaaatta
     3841 tcccccgcat tggcaaaagt ttctaccata ctgccatctt cgaatgaaaa tgttacctta
     3901 aacattcggc aaccaccttt ctcatagtcg taatagcctg taataaaaca gggaccgaag
     3961 accgaagcct tcagccccca taattatgta ttcatttatg tcggtcgaat attttattag
     4021 atttctcagc tatactgatt agatttccag gtaggaatct gcatacagtg tattgccttt
     4081 gaatacatca caggatttaa tagtttccat cagacgaagg tcgttaggat taacgattgc
     4141 agatgtaaga ccgttcatca tagccattgc tacaagagca gagtccatga tcggacggat
     4201 atgtttcggc ataccgttac tgttattgga aagaccacct gtggagttca gtcccatatc
     4261 agagaacatt ttgattgctt caagaacttc catctgtttg tcctgcattc cttttacaac
     4321 caggaataac gggtcaaacc agagatcttc agcttccata ccaagagaca tacctctttc
     4381 aagcatgttc tggcagtgca tcatacgttc atcattgtct gctgctacca taccggaaga
     4441 gcaaagtgcg atacagatgg catcgtttgc tgctgcaagg tcgatgtttg tgattctgtc
     4501 accagcatca gcagagttaa cgatcggttt tccttttgct ctgttatata cagagatacc
     4561 agcttcaata gctttcttgt ttgttgtatc cagtgcaagc ggaacattgt caaactctga
     4621 ctgaaggagc tgtactgccc atttcatcag atcttctcca tcgttctcag caggtccgat
     4681 gtttacatca aggtaagtag caccagcgtc aagctgctgt tttgctcttt tgatgatcgg
     4741 ctctggatct ctttctgtaa atgctttgtt tactgcaggt gcagtagtgg aaagtctttc
     4801 tccgattgtt acaaattttg ccataaccgt gttctccttt ttatttattt acacaggaat
     4861 aaaacctgta tgcttcttat taagagccag accggtcaga tgaccggtcc ggcatgtcat
     4921 tccgatcaga tctgaccgtc agcctgcata tcttttaaga atttaacaag ctgtacagct
     4981 tctcttggtc caacgatgat ttcccatcca ggaagttttg cttcaaggtc acccttaaga
     5041 actgctacct tacctgggat aataagcttt ctggatttta ccttaggctc aacattttct
     5101 ttgatgtaag cggaaatgct gttgccggag aatttaccag ctgcccagga tgtcagtacg
     5161 gaaagtccgc ctgcatcatt gattaccagg ttaagcggaa caccggaacg ctccagctcg
     5221 ccggatacta cgaaatatgt aagagcgaag tctacagtag taactactac cgcattctca
     5281 tcagcaccat ttaatggata gatgcctggc tcaactttca ttggtttctg cggatcagtg
     5341 aaaacgttct gacgcagacc atataatgga agagcttctg catatgtcat ctgctccata
     5401 acgatgatgg aaccatattt cattgtaaac atagatgcta aagctgcctg taagtgaagg
     5461 tcaccttttg cgatcttaac aaggtttacg atagatggat aaccaaatgt tctgtcctga
     5521 tctttcagag ctgcacgacg aacctgtaca gtgtttgcaa aggtttcttt gatgtcagcg
     5581 cctgttgtat caagaacaag gttcttgttt ccgagttttt caagagctgc tgttgtatca
     5641 tataattcat ttaagtcttt accggataca ccgagaacaa cacctgcttc tgtagcaact
     5701 gcgttcattg cttcatagtt ggaagcatct gcaccgttta agaccggttt gctgtctttg
     5761 catactgcaa gagctgcttt tgcgatttca ggatctttac attcaagaac taaagttctg
     5821 ccaagacctg cagctttttc tacaagtgca gtatatttag ctgcatctgc accttcgcca
     5881 cagtttacat atacaagttc agcatacatt ctttcaccga tacggtcata atctaccttc
     5941 gggatttctg caagtttcgc ctctactgta gcatcatcca tacatgtgca cagagctact
     6001 gcatatcttg gcttgcttac aaatgttttt tcatgtctga ataatactgt ttctccaccc
     6061 agagtgtgct cttctgcacc agtaccaatt ttgattgtct tcattggcgg agcagttgcc
     6121 tcggaaagag atgctaaagc ttcatcagac atatgcggac attgttcgat tttcatagcg
     6181 ccctgagcaa ctttcataga gaaagccata catgttgggc atccgcattc cttacagttt
     6241 ttctttggtg ttaatttaaa gatctgaata ccattcagtg ccattttatt tgttcctcct
     6301 attcaattac gcaagtgctt tgatcattct ggaaatagtt gcaacagctt ccggatgtct
     6361 taagatgact gcatcagatc cggctgcaag gtcagcagca gctgtcataa cttccatatc
     6421 gattccacgc tcttcttccg gtccccattc aggcatgtca gcttcagaag ctgtagcttc
     6481 ctttacgccc catgtctcag cggataccgg tgtaatgata ggcatctgca gcatgttatc
     6541 attctgagat aaagctgcac ctttgatacg atccattgta gatacaacgt actcatatcc
     6601 atatccggca gcagcactgc cgatattcat aacgatcttc tgtgcgttaa cgcctaactg
     6661 agtagttaca acgttaagct gtttagcaag gttgatatct acggcagatt ctgcacctac
     6721 gatctgatcg taagcaagtc ctgctgcagc accgattgct ttgtagtttt cttctttttc
     6781 agaaaggatc aatacatttc ttccctgaag agcttcagct actttcggaa gaagttcagc
     6841 gtctttttct acgttcttgc atccttctac tactaatggt gcatcaatgg aatctgcaac
     6901 gtcttttaca actgcaataa gttcatcaac agatttgttt acaccgttcg gatctccgcc
     6961 ttcaaggata agcgctacaa aatcagcacc ttccatagct gctgcttttt tagccatttc
     7021 tccgattgtg gaagctccgt cgtagtatgc tttgatacct tcggatacaa cattctcaag
     7081 acccatatca gagatctcca caccgatctt aggtgtgttt tctgatggtg catcaaaaga
     7141 ataaaatgga taagtagagt ctccgccgat tgttacagtc ttatctccgc tgccaatggt
     7201 gactgtatta atctttgcat tgaatttctg aagtttctga ttaaacggca tttttttggc
     7261 ctccttaaaa aaattactat gtgtatgtat cttttcgcag acttacacac tatgtcatgt
     7321 gtagtataca acattatcca gcccgttgac aagtacagtc tgtcatattt tgttaaaaaa
     7381 acaacaattt cacagctttc ctttattttc cataacaaag tgaaaaaaat tcggcaaatt
     7441 gccatatctg aactttgctg attcttcata cactccgcat atatttttat cagcaaatca
     7501 ttacggcagc cacattccgt ccttacgaaa cagaacgatt gtactttcac acgatcacat
     7561 tctgtatgtc cttgaaatat aatatactat ggtttttatc tatacgcttt tgagcgttta
     7621 aacccggagg cttattaaaa gcctccgcat gactcacata atacctccgg gaaaaccacc
     7681 atctttacat catcggatca agggctaatg ccggatggcc tttttctgta aggaatccaa
     7741 ccagtgtttc cggatcagta gcgattgttt catcaccgat catatctgta aagttttcaa
     7801 ttccgtagag ttcttttgct gtgttgttaa gacgctcagc aacaaactct ttcagttctt
     7861 ttggcatcca tacgatacgt tcaataccgc cttctgcctt catgaacttc ttggagctga
     7921 tgaaatgttt accatgtccc atgaaaccag gtgtctgaac accaccacct gtcatggatg
     7981 ccatttctga gaatgtcatt ccaagaggtg tcatgcctgc atactcacgg ttagcgataa
     8041 caacaccatt ggagaatggc tcgataccgc agatacactc gaagcatccg catgatgtca
     8101 taggatcctg catgatagag tacagtgtaa cgtgctctaa tgcaccctgg gataatttct
     8161 taacagcttc atctacatct tcataagaac caaggttctc atcaataggt ctttcttttg
     8221 taattacctg gcaaggtccg ttcggatcca gctcgttggt agcttttgca tccagccatg
     8281 aaacggcacc gcaaagtcca agtctctcag gtgtaacaac acatacgtga gacggggaga
     8341 atgcctggca gaggatacag ctgtaatata catctacaga ttcgtctgtc agagtattca
     8401 gacggtcatc acgtttctcg aagatcggga tagcaacttc atgacggatt cttgtacact
     8461 cagcaggatc tgtataaata gtaacttcac atttatcaac aactgcgtca aattcattct
     8521 taacctgtgt atagagaact tcaccgatat gtttgatttt gaagcctgca gcaaatgcat
     8581 ctttgctgat acggattctc tgcatatctc tctgtcctgt atggtataca ccttcgatac
     8641 agttgatgta gttatggaac ttacgctcga taacaggttc aaagtcaggc tgcatgtttt
     8701 tacctgcaac tttaacaaca tatgcaatgc tgttcttgct gccaagttcc atgtcgtcta
     8761 cttccggacc aacaactgta atcttatggt cttctacttc acttgcatca catgtatgta
     8821 caagctctgc acagtctaca cgggaaccat cgaattcaac ctgcatgtct ttacgacgga
     8881 taatctcacc ttcgaatgca gatgcgaaag caaccgggat atcgatgttt gtaattttga
     8941 ttttgatgtc acgtgcttcc agagaagttg cattccattt ggagatgtct ttctggcaga
     9001 tcaggctctt cggtactctt gcaacatctt cctggtttgt gataaccggg aatccaagag
     9061 cgatagcgcc tgcaccacaa gctacgatca catcatttaa cggtgcaaat gcattaacaa
     9121 atgcaggtac acgtttcatt gtgtaatcca tcagagttgc agcatcacct ggttttacgt
     9181 taccgaagat aagagctgca cgaagtgcta cagatactac atggataact gctgtaacgt
     9241 cttttccaag cgggataaca cgtacgttag cacctgtctt gtatccaact tcctctaact
     9301 ggtcaataac gtcaccaacc agagtgatca ggataccctg agactgatag gatttaacaa
     9361 ggtctgctgc ttcctgagcg gaaggagctt ttccaaggat aactgctaca cctgggatat
     9421 cgcctgttac aagcggtaca ccaagttcac ggatcactgc atctgcaaga tgtccgtagc
     9481 aaggagcttc ataaggaact gctccgtcaa tatatttcag aacttcgata aattctgcgc
     9541 agagagctgt agcaacacct gacataaata cgtcatttgt tcttttctct cttgtcataa
     9601 gagtttttac tactgcaaga gcatctttta actctgcaag agttccaacc tttgttcctg
     9661 ttactgcata gtagcatggt aaagaatatg ctgtatcagg gaagctgact gctttgtcag
     9721 cgccgtattt ttcaattgcc tggttgatgg caccctctgt aagtccataa accgcgtcat
     9781 ttcccgcaaa aacactttca aataaagtca ctttgtttac ctcctaaata tatgagatta
     9841 ttgacgatct atcttttctt ttatcttaat gatctcatca gtaactgttt tgctgaagtc
     9901 ataaggggat tttccctgtc tgtccgcatc aattacttct gtgttgtaat ggatcattcc
     9961 taaaagatct tcctgtggaa tccgttctct gataaagttt tcgtcatcct cgttgcgtac
    10021 tttgtttgca acaaccttta cctgagctac tcccagatcc tttgccagac gttttacatt
    10081 cttgtatgtc tgaacacttc ttgcacccgg ttcgatcact acgataaatg cgtccactcc
    10141 ttctgtggtt cctctgccga gatgttccag gccggcttcc atatcaagaa ttaccacatc
    10201 ttctcttctc agtaccagat tattaataat acgtttcagc attacatgct ccggacatac
    10261 acatccgcca ccgcctgtct cgacagttcc caggacaagg agacgcacgc cattacagac
    10321 cttaccatat ttctccggga tatcgtctac tttcggattc agatgataga actgatttcc
    10381 cgcagtcgca cctgtacgtt cttccacaag cttacgcatt ttggaaattg gtacaataga
    10441 atccagtgtt tcttcatcaa agcctaatgc aagaccaaga ttcgcatccg gatccacatc
    10501 tgctgcaagt accggtcttc cctctgctgc atacaacctg gccagcgttg ctgcaaaagt
    10561 agttttgcct acgccgcctt ttcctgtaac tgctattttc attttacgtc atccaccttt
    10621 tattacattt ttaagatcac agcagattag attcctaatg ctgttctctt ctcttcgatt
    10681 ctttcgatca tcagatcaac taatttctca atatctgttt ctactgtata agcagctcct
    10741 gtccattttc ttgttccctc tgtaagaagc tctcccattt ctgaagaacc ggaaacatat
    10801 ggatcaacac caaggaatgt atcaataccg gtacctacta catagttacc gatggataca
    10861 gctttttcag acatccactc aggagcacat ccaactacag gaagctgatt gatctgaaga
    10921 cctgcatctt ttgcaagttc agcagcaagg atcatcatac gggaaatatc tacgcatgat
    10981 cccatgtgga gtaccggtgg gatatcagcc agttcacaga cacgtttcag acctgcaccg
    11041 cagagatctt ttgcagattt gtccataaga cctgcttttg cagctgcctg tgcagaacat
    11101 ccggaagcaa tgacaacgat atcattggcg atacatttct tcatcagttc aatatgtgca
    11161 tagtcaggac ggatcttagg attgttacat ccaaccatag caacagcacc acggataaca
    11221 ccggaagtga tgcactcaag taatggtttt gttgttcctg tctcatcaac ctgagagttt
    11281 gtaacaccgt caagaacctt aacgattgct tctacggaat aaccaactgt agctttctgt
    11341 ttcagctgtg ggatatgtac aagttcaggt tttctgttct tgaagttgtc aatagccatc
    11401 ttgacgattg cttttgcatt ctctcctgct gtctcagcat tgaatctgat aaattcagca
    11461 tcaggcatct gagcgatcgg agaagttgtg ataaatttag tatggaagca tttgcttaaa
    11521 ggtcctaatg cagggaagat acactgaaca tctactacga tcgcttcgca ggcacctgtc
    11581 agtactacat tctcctgctg caggaagtta ccggccatcg gaacaccgcg acgcatagct
    11641 acttcgtttg aagtacagca tacaccggaa acagtgattc cttttgctcc tacagatttt
    11701 gcataatcga tcatttcttt gctgtctgca tattcacaga tcatctcgga aagactcgga
    11761 tcatgtccgt gtacaacgat gtttacattc tcttcaacca ttacaccaag gttagcttca
    11821 gtgtcaattg gcttcggagt tccgaataat acgtcagaga actctgttcc catcatggaa
    11881 ccgccccatc catcggcaag accgcagcgg atagactgtt ttacaagagc ttccggaaga
    11941 gaagaacatc ccatatgagc catatgtaaa gaagtggaaa cctcacgatc gatcgcacgt
    12001 ggtgcaattt cattttcaat cagtttctct ttctgtcctg caggcattct gtcaaggaat
    12061 ctctgatatc caaatggttt accatattcc atcaatcctg tctcagccat ttcatgagcc
    12121 agatcataga tatcttttcc ttctgtctct acgccccatt cttttg
//
