LOCUS       gnlProkkaAJGMHPLF_21   21589 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJGMHPLF_21.
ACCESSION   gnlProkkaAJGMHPLF_21
VERSION     gnlProkkaAJGMHPLF_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:42:55
            Original ID  :: gnl|Prokka|AJGMHPLF_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 272
            Orig. end    :: 21861
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21589
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11589]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21589
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21589
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             588..1538
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MQKDYETFVEKLEIGIYEATGIPRENISFEKEGGRFAPVGDRLLV
                     KFAEHDDAWEVCGLYTQELFKSYQNGSPFEEIIKEITDDLNRIKKADIYEKTRVIRDYE
                     KTKPRLFIRLLNADKYSADLQDAVYKTLGDIALVLYMKVTEYEGCVTSTKIRQGMLEQW
                     GKECDEVFQEAILNTYFMSPPRIYRWEQMIFNPEYEGESFMNLGDKCELKKDAMGNCLS
                     TTKKTNGAVAVFLPGVAEQLAYMLDSDFYMVFTSVHEVMIHNDKFVEPEDLQCVLRDTI
                     REATPKEDYLTSRIYQYNRETHKFICVTPLEKDEK"
     CDS             complement(1613..2407)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.4; E-value:
                     3.5e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MLELKNIYKTFNPGTINEKRALNGLNLKLNEGDFVTVIGGNGAGK
                     STMLNAVAGTWPVDEGQILIDNIDVTKLSEHKRATYLGRVFQDPMTGTAATMGIEENLA
                     LAKRRGKSRLLRSGITKAEREEYKELLKILGLGLEDRLTSKVGLLSGGQRQALTLLMAT
                     LQKPKLLLLDEHTAALDPKTAAKVLEITDMIVNRDHLTTLMITHNMKDAIAHGNRLIMM
                     MEGKIILDIQGEEKKKLTVKNLLDQFEKASGEEFSNDSALLG"
     CDS             complement(2410..3327)
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 68; E-value:
                     1.2e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MQILTLITALPGAVAQGLIWGIMAIGVYITFRILDIADLTVDGTM
                     CTGGAVCIMMMLSGHNVWISMLAATLAGMLAGLVTGIFHTFMGIPAILAGILTQLSLYS
                     VNLKIMGKANQAINVDKYNLLVSLRHIKNASLSKNTIFIVAVMCILLIAILYWFFGTEL
                     GCSLRATGCNPNMSRAQGINTNRNKVLGLMISNGLVGLSSALLAQYQGFADVNMGRGSI
                     VIGLAAVIIGEAIFGRIFRNFALRLLAVIFGSILYYLVLQIVIWMGIDTDLLKMLSAIV
                     VALFLAFPYWKGKYFNKPAKRGGK"
     CDS             complement(3478..4464)
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MKRKALAITLAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGEDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFDGTVGGNISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVATTATDASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNFTKEYNKDICEELGIEVPDDYVAIGEAAEETAK"
     CDS             4728..5492
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFREIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADRMLYQLLEKGYPSFMLHENGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTVIVTK"
     CDS             5784..6386
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MMNDVYEKFLKSSEEFIFAENKPEKSDIIFVPGNGYPQMAEKAAE
                     LFKKGMADWILPSGKYSVVNGKFSGVLEKSNVYNKEYGTEWEFLRDVLIKNGVPDQKIL
                     KEDQATFTYENAIYSRQVTDHAELEIERAILCCKSYHARRCLMYYQLLYPKTEFYVVPV
                     NADGITRENWRKNEEGIDAVTGELSRIVKQFSLMLER"
     CDS             complement(6390..7673)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 355.5; E-value: 7.1e-108)"
                     /gene_kind="other"
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MDSSIAFQAVAILILIALSSFFSSAETAMTTVNKIRIQSLAEQGN
                     KRAVILEKIISDSPKMLSTVLIGNNIVNMSVSSLMTTLTIKILGNAYVGIATGILTLLI
                     LIFGEITPKNLATIHAEKLSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEK
                     ANAMTEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFS
                     YDELMAVFSEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKNKPFSIRNILREPYFTYEY
                     KATADLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEI
                     QPEREYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRL
                     VVDRLDKNRIELVHIWLPEKKTETEEQP"
     CDS             8019..9527
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MSNNINRIRKNKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAE
                     SQENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDSDNSDKTEGSGKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNQTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGAGDNIFDNPVLPDDKDDRPTDAEDSLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDAGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSMNDSSDSNNGSSSDQNDNST
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVAVFIKKRKK"
     CDS             9577..9927
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGRIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_11"
                     /sec_met_domain="TIGR03973 (E-value: 1.3e-27, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.7e-27, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             10222..11589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_12"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6.3e-29,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.3e-16, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.4e-14, bitscore: 45.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.5e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDALAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             11701..14109
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRIPGIVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLVVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFV
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             14191..15903
                     /locus_tag="ctg21_14"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARLIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILEKKISQKAKVRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVADGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKGMTVIITD
                     HHEVPYREEKGERQMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYIAALYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLCRLKNTKNQGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTATRSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHRPAFVLTGGETSAKGSGR
                     SIESYSMYEELVKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVNCTLTDEELRPKI
                     VIDVPMPVSYITKELVEQISLLEPFGKGNTKPVFAQKNLRVLDHSIIGKNKNVVKLKLL
                     DPQGISVEGIYFGEAEDFVNFIREKDSISVTYYPEINRFRGRESLQIIIQNYC"
     CDS             16051..16575
                     /locus_tag="ctg21_15"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDIDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             16613..18943
                     /locus_tag="ctg21_16"
                     /transl_table=11
                     /translation="MTEVTKSTEAKKDEMQVEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVHKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKAPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKIANYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYTAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             19008..19637
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     163.1; E-value: 9.6e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_17"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYLLKNKETGELIIVDPADCPEKIEMKI
                     SRMNGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGQGC
                     SIVPDVFLEDLDVIRLAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVRSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             19630..21144
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_18"
                     /sec_met_domain="PF04055 (E-value: 2.2e-24, bitscore: 78.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFENRDFEHDVYELIKAFYPEAEIHTLYENAEAEYDLRF
                     SVERDNDSYIIKYERTENLSKQETEQKGVISADILSKENAGCGIQDAHALRKENKDNIK
                     YALYQLLIKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVEALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMAIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFHLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQVRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMGPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 aaagacatgg tttctaaaca aggtctttca gaccgatttt atatcgcatc tgctgcaacc
       61 agcactgagg agatatggaa tggaatcggg aatccggtat atcctccggc gcgagaggag
      121 cttgctaagc atgggattga ttgtaagggt aagcgcgcag ttcaactgac gaaggcagat
      181 tatgataaat atgattatat tctcggtatg gaccactgga atctgaagaa tatgttaaga
      241 atattgaaat cagatccaga ggacaaggtt aaacttcttc tggattacag tgatgatccg
      301 agggatatcg cagatccgtg gtatacaggt ggatttgatg tcacatattc ggatgtggtg
      361 gagggctgtg aggcttttct ggaatatctg aaagataaaa agaaactgta ataaatattg
      421 tcgatgaaat ttactttaca aatagctgtg gctattttat actatgtcta cagcgactct
      481 taagggggct ttcgctccct tattttcttt tttccgaaaa cggaaagtca acattcaaat
      541 cagggcatcc tgcccgtatt attttcaaag taagaaagga actgaatatg cagaaagact
      601 atgaaacatt cgtagagaaa ctggagattg gtatttacga ggctacaggg attccgaggg
      661 aaaatatttc ttttgagaaa gaaggcggga ggtttgcgcc tgtaggagac agactgctgg
      721 tgaagtttgc agagcatgat gatgcctggg aggtctgtgg actttataca caggaacttt
      781 ttaaatctta tcagaatggc agtccgtttg aggaaattat aaaagaaatc acagatgatc
      841 tgaatcggat aaaaaaggcg gatatttatg agaaaacaag agtgatcagg gattatgaga
      901 agacaaaacc ccgcctgttt ataagattgc tgaatgcaga taaatattcc gcggatcttc
      961 aggatgcggt gtataaaact cttggtgata ttgcacttgt gctttatatg aaagttacgg
     1021 aatatgaagg atgtgtgaca agtacaaaaa tccggcaggg aatgctggaa cagtggggga
     1081 aagaatgtga tgaagtgttt caggaggcga ttctcaatac gtatttcatg agtccgccaa
     1141 gaatttacag atgggaacag atgattttta atccggaata tgaaggtgaa agttttatga
     1201 atctgggtga taagtgtgaa ttgaagaaag atgcaatggg aaattgtctc agtacaacga
     1261 agaaaacaaa tggtgcagtt gcagtgttcc tgccgggagt ggcagaacaa ttggcatata
     1321 tgctggattc cgatttctat atggtgttta ccagtgtaca tgaggtaatg atccataatg
     1381 ataaatttgt agaacctgaa gatttgcagt gtgttttgcg ggatacgatc agggaggcta
     1441 caccgaaaga ggactatctg acgtcgagaa tctaccagta caatagggaa acacataaat
     1501 ttatctgtgt aactccgctg gaaaaagatg agaaataaaa atatgagagt actccataaa
     1561 aaagtactct catataaagg atatttagaa acgttatgag taatttatac ggttatccga
     1621 gcagtgcaga gtcattgctg aactcttctc cgcttgcttt ttcaaactga tccagaaggt
     1681 ttttaactgt cagttttttc ttttcttctc cctggatatc cagaatgatt tttccttcca
     1741 tcatcatgat cagacgattg ccatgtgcaa tagcgtcctt catgttgtgg gtgatcatca
     1801 atgtcgtaag gtgatcgcgg tttacgatca tatctgtaat ttccagaact ttggcagctg
     1861 tttttggatc aagagctgcg gtatgttcgt ccagaagcag aagctttggt ttctgaagcg
     1921 ttgccatcag aagagtaaga gcctgtctct gaccacccga gagaagtcct actttagaag
     1981 tcagtctgtc ttccagacca agaccaagaa ttttcaggag ctctttgtat tcttcgcgct
     2041 cagctttagt gattccggag cggagaagac gggattttcc gcggcgtttt gcaagtgcaa
     2101 ggttttcctc gatacccatt gttgcagcgg ttcctgtcat tggatcctga aacacacgtc
     2161 caaggtatgt agcacgttta tgttcagaaa gttttgtaac atcaatattg tcgataagga
     2221 tctgtccttc atcaaccggc caggttcctg caacagcatt tagcatagta gatttgccgg
     2281 cgccgtttcc tccgataaca gttacaaaat cgccttcgtt cagcttcagg ttcagaccat
     2341 ttaatgcacg tttctcatta atggttccgg gattaaaggt tttatagata tttttaagtt
     2401 caagcatttt tatttacctc cccttttggc tggtttatta aagtatttgc ctttccagta
     2461 tgggaatgca aggaagagag caactacgat tgcggacagc atcttcagca ggtcagtgtc
     2521 gatacccatc cagataacaa tctgaagtac cagataatac agaatggaac cgaagataac
     2581 tgctaacaga cgaagggcaa agttgcggaa aatacgtcca aagattgcct caccaataat
     2641 aactgctgcc agaccgataa cgatggaacc acgtcccatg ttgacatctg caaatccctg
     2701 atactgtgca aggagtgcac tggaaagtcc taccagaccg ttggaaatca taagtccgag
     2761 aactttattc ctgtttgtgt tgataccctg ggcgcgtgac atatttgggt tacatccggt
     2821 tgcgcgaagg gaacagccaa gctctgttcc aaagaaccag tagagaatgg caatcaggag
     2881 aatacacata actgctacaa taaaaattgt gtttttggaa agagatgcat tttttatatg
     2941 tcgcagggaa accagaagat tatatttatc aacgttgatt gcctgatttg cttttcccat
     3001 gatcttcagg tttacggaat acagagataa ctgtgtcagg attccggcaa ggattgcggg
     3061 aattcccata aaggtgtgaa aaattccggt cacaaggcct gccagcattc cggcgagagt
     3121 agcggccaac atagaaatcc agacattatg accggaaagc atcatcataa tacacactgc
     3181 accaccggtg cacatagtgc catcaactgt aaggtctgca atatcaagaa tacggaaagt
     3241 gatataaaca ccgattgcca taattcccca gatcagaccc tgggctactg cacccggaag
     3301 tgcagtgatt aatgttaaaa tttgcatttg taatttcctc ctgttgagat gcgaaaagcg
     3361 agagaggcgt caaacctttc ccgctgatcg catataaatt gaatttttta taactgtttg
     3421 ataagctgtt atttaaaatc ctgttggtgt gagtattttt caactgtctg accggattta
     3481 tttggcagtt tcttcagcag cctcgccgat tgcaacataa tcgtccggaa cttcgatgcc
     3541 cagctcttcg cagatatctt tgttatattc ttttgtgaag tttggtgcat attcgatcgg
     3601 cattgtggaa atatcttcac cgtcctttaa aatcttaaca gccatcttac cggttgtaac
     3661 accaaggtca taatagctga tggaaagtgt cgcaacaccg catccgctgc agataccttc
     3721 ttcgcctgtg attaccggaa cttttgccgg aaggcagatg ttgttgatga tctctgtgtt
     3781 ggaagcaact gtattatctg tcggtacata aattacatca cttgcgtcag ttgctgttgt
     3841 agcaacagaa gagagatcat tagagtcaga gaatgcataa tattcacatg tatatccgag
     3901 tttttcaagt tcagctttta ctgtatctac ctgatactga gagtttgctt cggcagaaca
     3961 gtagagaaga cctacatttt ttgcatccgg gaaaagttca ttgagcattg ctgcctgttg
     4021 atcaagggga gcaaggtctg cagttccgga aatatttccg cccacagtcc cgtcgaaatc
     4081 atccagtcca agtgcaacac cgtattcagt aacagaagta ccaagaatcg gaatatcgct
     4141 tgtccctgct gcagctgcct gaagagcagg agttgcattt gcaagaatca ggtcaacatt
     4201 attggaaacg aagctgttaa tgattgtaga acaggtgttg gaatctccct gtgcgttctg
     4261 ctcgtcaaag gtaactgcgt cttctcccag ttctttggtg acttcatcct tgaatccctg
     4321 tgtcgcagcg tcgagagctt cgtgctgtac aagctgacag ataccgattg tatatttgtc
     4381 tccgtcagca gcacttgctg ttactgcgca ggttcccata gccatggctg ctgcaagagt
     4441 gattgctaat gcttttcttt tcataatgat atatcctcct aatataatgt ttaaattaag
     4501 tcaggtaaga attgcgttta ttatttgata atataaaact tacctgaatc cgaaagattt
     4561 tctgcaggga aagcagtact ggtaaatgat tcggataatg tcatcggact attcgactat
     4621 gacgttttaa agtataacgc tttagtgtga aaaagtcaag cgacctgcac aattatattt
     4681 ttaattcata tagtataaag agtatatgaa gaaagcagag tgtcgtcatg gcatattcga
     4741 tcatgctgga tgccggacat ggaggtcagg atccgggagc cgtatataag ggaagacagg
     4801 aaaagaatga caatcttaaa cttgctcttg cggtaggtga gattttaaaa aataaaggga
     4861 ttgatatctc ttatacccgt accggtgatg tctatcagac accttttgag aaggcacagc
     4921 ttgcaaatca ggcaggagta gattacttta tttcatttca tcgaaacagc agcccaaagg
     4981 aaaatcagta taatggagcg gaagttctga tttatgataa aagcgggatt aaatatcaga
     5041 tggctgagaa tattctggga gctctgggag aagtgggatt ccgcgaaatc ggtgtaaaag
     5101 agcggccggg acttgtggtc ctcaggcgaa ccaggatgcc ggctctttta atagaaaccg
     5161 gatttatcaa ttctgaagaa gataataaac tgtttgataa caagtttagc gatatagctc
     5221 agggaattgc agatgcgatt cttggaagcc tggatgagga aacagtgcag gaaccgcttt
     5281 attacagagt gcagactgga gcgttcagaa aaaaagagaa tgcggaccgt atgttatatc
     5341 agttactgga aaaaggttat ccctctttta tgttacatga aaacggattg tataaagttc
     5401 agacaggtgc ctatcagcag attggtaatg cagtaaatat ggagcagaga ctgagggatg
     5461 atggttacag tacggttatt gtgacaaaat agctttctgg aaatattgga agtctgcgga
     5521 ttttttgttt aaccgaatca aataagtccc ctgcggaggt tgcgaaaagc aataagtagt
     5581 gggggacata gttttaagaa ttaacttggt tgtacgttaa tagaaaaaat atggtacact
     5641 gtatctatct atagaaattc catagaaatc ttcgtaaata atgcatattg ttccggttca
     5701 tcagagcgtg aaattctgtt ggactgttac aaacgcatta tttgagaggt gctgtagaaa
     5761 aaacagataa cgaggagtta gtaatgatga atgacgtata tgaaaaattt ttaaaaagtt
     5821 cagaagagtt tatttttgca gaaaacaagc cggaaaaatc tgatattatt tttgtccctg
     5881 gaaatggtta tccgcagatg gcggaaaaag cagcagaatt gtttaagaaa gggatggcgg
     5941 actggattct gcccagtgga aaatacagcg tagtaaatgg aaagttttca ggcgttcttg
     6001 aaaaaagcaa tgtatataat aaggaatatg gaacagaatg ggaatttctc agggatgttc
     6061 ttataaaaaa cggagttccg gatcagaaaa tcctgaaaga agatcaggca acctttactt
     6121 atgagaacgc aatttattcc agacaggtga cagatcatgc agaactggaa atagaaagag
     6181 cgattttgtg ctgcaaatct taccatgcaa gaagatgtct gatgtattat cagctcttgt
     6241 atccgaaaac agaattttat gtggtgcctg tgaatgcaga tggaattacc agagaaaact
     6301 ggagaaagaa cgaagaagga attgatgcgg ttacaggaga actctccaga atcgtgaaac
     6361 aattttcact gatgctggag agatgacagt tacggctgtt cttctgtttc ggttttcttc
     6421 tcgggaagcc agatgtggac aagttcgatt ctgtttttgt ccagacggtc aacaaccagg
     6481 cggatgccac tttcaagtgt gacagactga ccctctttgg gaaggcagtc aagctgttca
     6541 ataatatatc cgccaataga gtcataatct tcagattcca gattaatatg gagggcttcg
     6601 ttgatatcat ccagcttggc agaaccctga acaacatatt ctctttcagg ctggatttct
     6661 ttaatatctt cgacttcatc ctcatcgtat tcgtcgcgaa tctcacctac aatctcttcc
     6721 aacaggtctt ccaatgtgac cagaccggct gtggcaccgt attcgtccag aacgattgcc
     6781 agattgacgg atgctttacg catttcgatc atcaggtctg ctgtagcttt gtattcatag
     6841 gtaaaataag gctcacgcag gatgttgcgg attgaaaaag gtttgttctt tggataaaca
     6901 agaagatctt tcatattgat aataccgatt acgttatcag tgttgtcctc ataaaccgga
     6961 aaacgggtat gcatatcttc actgaagacc gccataagtt catcatagga aaaattgata
     7021 tctataaagg tcatgtcgat tctgggaatc atgacatctt ttgcagttga atcgccaaaa
     7081 tcaaacacat tgtagatcat ctgtttttct tcgttttcaa tgacgccgtc tttttcacct
     7141 acattgacga gggtacgcag ttcatgttca gtcatggcat ttgccttttc gtccgggtta
     7201 acatgcagaa tgaccagtac accttctgtt attttattta caataaaaac aacgggagta
     7261 aggagaatca taagcccgta tattattctt gaataggcca gggacaattt ctctgcatgg
     7321 attgttgcca ggttttttgg tgttatctcg ccaaaaataa gaatcaacag agtcagaatg
     7381 ccagttgcga ttcctacata tgcgtttccc agaatcttta tggtgagtgt agtcatgaga
     7441 gaagaaacag acatatttac aatgttgttt ccgattaata cggtactgag catctttgga
     7501 gaatcggaaa ttattttttc cagaataaca gcacgtttgt tgccctgctc ggcaagagac
     7561 tgtatccgaa ttttatttac ggttgtcata gcggtttccg cagaagaaaa aaatgaagaa
     7621 agtgcgatca gtatcagaat cgccaccgcc tgaaaggcaa tacttgaatc caagatttat
     7681 tcactccttt tgattatttt tttattgatt gaatcatatc ataaaacatt taagcaaaat
     7741 atacatgatt tcatataaaa aatcaagaaa aagcttttgg ttcaaagata gtataaaaaa
     7801 atttaaaaga ggactgtcga aaaagtaaga tttgtgttat aattcactcg attaaaatga
     7861 aaaaaaacat tacagaatat ttacaaaatg ataaaagttt gataatatac agatatgtaa
     7921 tattgttgta ttacgtaaaa aagaactgat atttggctga aagtaaaaaa atgattatca
     7981 ggaaacataa gaatcgaata taaatataga ggtgcgatat gtccaataat ataaatagaa
     8041 taagaaaaaa taaattaaaa ggaacgggta tttttgcggc agcggcttta acagcggctt
     8101 tgattgcagg aaataatata ccgggtgtaa caagacaggt cagtgcggct gagtcacagg
     8161 agaatactgt gtcttctctg atcccggaca acatcacgct tgataagcca gtagaacttg
     8221 cggatgtaga acttccggca acggaatatg gaacttttga atgggcagat ggaagtttcg
     8281 ttcctgcaca gcgtgtacag agctgtgagg tacttcttat accggcagaa ggacaggatt
     8341 taagccatgt ggatggatgg gatccggaga gcggcgcggt tgtcggttac atcaatgtaa
     8401 tagtgaacag tattacggat agtgataatt ctgataagac agaaggctca ggtaaaacag
     8461 atccaacaga aaatgcagat ccaacagaaa cgcctgaaac ttcgtcagaa aaacctgccg
     8521 cagatgaaaa cgctgataca gacaataaag aagataagga aagtaaatca gatcaggata
     8581 atcaaactga tacagacaat gaagagaata agattgaaga agataaaaca gataataaaa
     8641 acaacaaaga taataacagc aatgcagata agacggataa agatacagaa actaccggta
     8701 agctggaacc tgcagatgat atgacacagg ataaagaaga tacgaagaaa gatgatgaag
     8761 atggcgcagg tgataatatc tttgataatc ctgttctgcc ggacgataag gatgaccgtc
     8821 ctacagatgc agaggattct ctttctgatg aagaaaaaga agagagggcc gcacttaatc
     8881 atacctgcga cggtattaca gtaagcggag ttaatcttcc atggtatgta cagttcagag
     8941 tttcaagcgg tgacagctat cagtttacca atgaatcaga tgcaatgatt ttccagtctt
     9001 atgaatttga actctgggat cttaagaata atacagaata tgagatccct aatggagatt
     9061 atatcagtgt cactgtgcca gtaaaatccg gatatcagta tactatcgaa catctcctgg
     9121 ataacggggc aactgagacg attattccga gtgtagagaa tggtattatg gtattcagca
     9181 cacattcttt cagtccattt ggaattgcag gaagcagaca attagtagga cctgatgcgg
     9241 ggaatgatac ggacgacaca gatgcggtaa ctcctgcacc ggcttcctcc gacagtcaga
     9301 gttctgattc cggaaagaac aatacagtat ctatgaatga cagttctgac agcaataatg
     9361 gttcttcttc tgatcagaat gataattcaa cggaaaataa agctgtgaaa aataacaata
     9421 cagtaaatac cggagataca acatcaatta tgccgtttgt gatactgttt gtggcagctg
     9481 cagtgatcgc cggtgtggct gtatttataa aaaagagaaa gaaataaaag aataacactg
     9541 attcctcccc catatagttt aacaggaggg gaagcaatga aagtcagagc aattttgaaa
     9601 tcactattat ttgcatatgc attaacagga gtggcattac tgcttttggc cctggtactg
     9661 tttgcttttg atctgggaga aacagctgta gatgcgggga ttattataat ttatgtactt
     9721 gcatgtttca tgggaggttt tatggccggc agaattgtgc gtaaagacaa atatctgtgg
     9781 ggtgttatca caggtctggc ttactatgta ttactgttga ctgtctctgt tatggcaaaa
     9841 ggcggctggg atatgagtgc agcgcatgca gttacaacat tttttatgtg cacaggcggc
     9901 ggaacactgg gtggaatgct gtcgtaaaaa aaagctttta aaatgaaaag atatatgata
     9961 tactatgcca agaatataat tacataagga ggatagagtt atggaacata tcaaaaccct
    10021 gaatacaaag aatttacaga acactgtaaa aaaaggtgga tgtggcgagt gccagacttc
    10081 ctgccagtcc gcatgtaaaa cttcctgtac agtaggaaac cagagctgcg agcagaaata
    10141 agatcagcta tggagaaatg agataagcag cggaactttt attccgctgc ttatcttacg
    10201 cttagaaagg attttagtaa aatgagtctg attcaccgtt ataaaagcaa tggctttaat
    10261 attgtactgg atatcaacag tggatgcatc catctggtag atgaggttac atatgaggtt
    10321 cttccatatc tggaagaggg ccttggcaca gaagctattg cagagaaact ggaaaacaaa
    10381 tataacagag aagatattga gacatctgta agagaatgta ataagctgaa agaagatgga
    10441 atgcttttta caaaagatgt ttatgagaat gtaattgaag aattttcaaa taaccggcag
    10501 accgttgtaa aagcattgtg cctgcacatt gctcatgact gcaatctggc ctgccgttat
    10561 tgttttgccg aagaaggcga atatcatggc agaagagctc ttatgtccta tgaagtcggt
    10621 aaaaaagctc ttgatttcct gatcgcgaac tccggttcca gaaaaaacct ggaagtagat
    10681 ttctttggcg gcgagccgct gatgaactgg caggttgtaa aagatctggt aaaatatggc
    10741 agagagcagg aaaagcttca caataagaaa ttccgtttca ctttaacaac aaacggagtt
    10801 cttctgaatg atgaagtaat ggaattctgc aataaagaga tgggcaacgt tgtactgagt
    10861 gtggacggac gtaaggaagt acatgactat atgcgtccat tcagaaaagg tgcaggaagc
    10921 tatgacctga tcatgccaaa gttccagaag tttgcagaat ccagaaatca ggacaagtat
    10981 tatgtaagag gtacttttac tcaccataat cttgatttct ccaaggatgt gcttcatctg
    11041 gcagatcttg gattcaaaca gatttccgta gagcctgtag ttgcggctga tacggaggaa
    11101 tatgcgatcc gcgaggagga tatcccccag atcatggaag agtatgatgc tcttgcaaaa
    11161 gaaatgatta aaagagagaa agagggaaaa ggatttaact tcttccattt tatgatcgac
    11221 cttacaggtg gcccttgtgt atacaagaga ctgtcaggct gcggttcagg aacagagtac
    11281 ctggctgtaa caccctgggg tgatttttac ccatgtcacc agtttgttgg tgaagaacag
    11341 tatctcatgg gaaatgtaga cgaaggcatt acaaagccgg aaatccagaa ggaattcggc
    11401 ggatgcaacg tttacacaaa gaaagactgc aaagactgct tcgcacgttt ctactgtagt
    11461 ggtggatgtg cggcaaatgc attccatttc cagggagata tcaaaggcaa ttatgaaatc
    11521 ggatgcgaac tccagagaaa acgtgtggag tgcgccatca tgataaaagc cgcactggca
    11581 tgtgattagt gggcagtaat ctgtctgact gataccgccg tcggctgtta tcataacaga
    11641 aaatggctgg caggcggatg aacatgaccg cggacaaaaa atcaagaagg gaaaagaact
    11701 atgaagaaaa gtaaaggaat cgtagtgctg cttctgacac tgatcctgac tgtgttcttt
    11761 tgctttactg cagccgtagg tatcggtcct accggaaccg gtgcagcaaa acatatcaac
    11821 acgggtcttg atcttgccgg tggtgtcagc attacctacc aggctaagga gagcaatccg
    11881 acaagcgaag agatgtcaga tacgatctac aagcttcaga agcgtgtaga gcagtacagt
    11941 actgaggctc aggtatacca ggaaggatca gaccgtatta cagttgaaat tcctggtgtt
    12001 acagatgcag atactattct gaatgatctg ggtaaaccag gttccctgta tttcatcact
    12061 aaagaagatg ctgacggaaa ccagaacttt actacaggac aggatggata tgttctctcc
    12121 agaactatgg atgagatcaa ggaatccgga agtgttgttc tggaaggttc tgatgtagca
    12181 gatgcccagg gtggtgcgat tcagaatcag aacacaagtg caaaggaata tgtggtaagt
    12241 cttactctta cttctgatgg agaaaacagt ggtaaaacaa aatttgcaga agctacaaag
    12301 aataatgtag gcaagcagat cgctatcgtc tatgacaata acattatcag tgctccgaat
    12361 gtaaatgaag agatttccgg tggaaaagca cagatcagcg gaatgtctga cctggaagaa
    12421 gcacagaacc ttgcttctta tatccgtatc ggttctctgg gactggaact ggaagaactt
    12481 cgttccagtg ttgtagctgc acagcttggt gaagaagcaa tctctacaag tgttcttgca
    12541 ggtgcgatcg gtctgatcat cgttattatc tttatgatca ttgcataccg catacctggt
    12601 atagttgcag gtattgcact gattctttat acatcattaa tgctgattac gctgaatgcc
    12661 tttgatatta ctcttactct tccgggtatt gcgggtatta tccttggtat cggtatggcg
    12721 gtggatgcca atgttattat ttatgcccga atcagagagg aaattggtgc aggagtttca
    12781 gtaaggaatt ctattaagtc cggtttcagc aaagctttct ctgcaatctt tgatggaaat
    12841 attacaacgc tgatcgcagc ctttgtgctg atgtggcttg gttcaggtac tgttaaggga
    12901 tttgcttata cacttgccct tggtatcgtg atctccatgt ttacagcact ggttgtatcc
    12961 agactggttg taaatgcact ttatgcagtt ggtgtgcgtg atccgaaatt ctacggatct
    13021 gcaaaagaac gtaaggcagt tgattttctt ggaaagaaga aagtattctt tgttatttcc
    13081 attatcctga tcctctgcgg tccggcagcg atgtttgcta attcacatgc aggaaacaaa
    13141 gcgttaaatt acagccttga gttctcaggc ggtacttcta caactgttac atttaatgaa
    13201 gatatggata tcaagaccat tgattccgaa gtaactcctg ttgtagaaga ggtgacagga
    13261 gataagaatg ttcagcctac aaaggtagtc ggaacaaatc aggttgtgat caaaacacgt
    13321 tctctgaatc agagcgaacg tgaagctctg cagagtgcac tggttgagaa atttggtgta
    13381 gatgacagca caatttccac agaaagtatt tcttctacag taagtagtga aatgcgtcgt
    13441 gatgcgatcg tagccgttat agtagctaca atctgtatgc ttctttatat ctggttcaga
    13501 tttaaagaca tccgttttgc aagcagtgcg gtattggcgc ttctgcatga tgttctggtt
    13561 gtacttgcat tctatgctat tgccagagta tctgtcggta atacatttat tgcctgcatg
    13621 cttacgatcg taggttattc tatcaatgct acaatcgtta tttttgaccg tatacgtgag
    13681 aaccttcaca gtggttccag agaaaaactg gcagaaattg taaacacaag tatcactcag
    13741 actcttacaa gaagtattta tacctctttt acaacttttg ttatggtagc tgttctttat
    13801 atcatgggtg tttcttctat ccgtgaattt gcagcacctc tgatggttgg tgttcttgtc
    13861 ggtgcatatt cttctgtatg tattacaggt gcgttatggt atgtgatgaa aaagaaattt
    13921 gcaggaaaag gacagccggc aattgctgca gcttccgcat ctgcaaagtc ctcttcaaag
    13981 ccgaagaaag cacgtgatgt atcacagaaa gatccgactc agccaaagaa gaaaaacaga
    14041 aaaagagtag ctgaacgtct ggctgccgaa gaagcagcta aaaaacagca gaatgatgat
    14101 gctgaataaa acaataagtg tctgaaaaac aggcagacag aaatatcccg gggtaaaact
    14161 ccgggatatt tttatgagga gagaaaatat atggagaaat gggtaatagc agcaaaaaga
    14221 gcagatttta accagatcgg tcaacagttt catattgatc cggtgattgc gagactgatc
    14281 aggaacagag atgtgatcgg agaagataag ataagagagt atctgtcagg aacagtacaa
    14341 gagcttcctt ctccctggct gatgaaggat atggaaaaag ctgtagatat cctggagaaa
    14401 aaaatatcac agaaagcaaa agtccgtatt attggtgatt atgatattga tggtgtgacc
    14461 tctacataca ttttaatgaa aggccttgcg aggatcggag cagatgtgga tacttatatt
    14521 ccggacagag ttgcagacgg atatgggatt catgcacatc ttatagaaag agcggaaacg
    14581 gaccggatcg atacgatcgt gacctgtgat aatggaattg ctgcggctgc tgaaatccag
    14641 atggcaaagg ataaggggat gacagtgatt attacagatc atcatgaggt tccttacagg
    14701 gaggaaaagg gagaacgcca gatggtgctt cctccggcag atgcgatttt gaatccgaaa
    14761 caatatgatt gtccataccc gaataaaaac ctgtgtgggg cagtggtggc ctttaaatat
    14821 attgcagcac tttacgagag atttggcgtt ccggcagagg agctggaaga ttattatgaa
    14881 ctggcggcta ttgcaacagt aggagatgtt atggatcttc agggagagaa caggattctg
    14941 gtaaaagaag ggctgtgccg tctgaaaaat accaaaaatc aaggattgca ggaactgatc
    15001 cgagcaaatt ctctggaaga tgctaaaatc acagcttatc atatcggatt tgtgctggga
    15061 ccatgtatca atgccagtgg cagactggat acagctaccc gttctcttgc acttctcaat
    15121 gcaaaaacaa aggaagaagc agcaaggctt gccggagatc ttacagctct taatcagagc
    15181 cgaaaagctc tcactgagaa aggaaaagaa gaggcaatcc ggatcataga gactacagag
    15241 ctgaaaaatg acagagtact ggtagtttat cttccggatt gtcatgaaag tcttgccggt
    15301 attatagcag gcaggatcag ggaaaaatat cacaggcctg cctttgtatt gacgggcggt
    15361 gagacaagtg caaaaggaag cggaaggtca atagaaagtt actctatgta tgaagaactg
    15421 gtaaaatgtg cagacctgat gatacagttt ggaggtcatc cgatggcagc aggtctttct
    15481 atagaagaaa aaaatataga agaattccgg agacgtctca atgtcaactg tacgttgacg
    15541 gacgaagaat tgcgtcctaa gatcgtgatt gatgtgccga tgcctgtgtc ttatattaca
    15601 aaagaactgg tagaacagat ttcgcttctg gaaccctttg gaaaagggaa tacaaaaccg
    15661 gtctttgcac agaaaaatct cagagtgctt gatcacagta ttatcgggaa aaataaaaat
    15721 gtagtaaaat taaaacttct cgatccgcag gggatttcag tggaaggcat ttatttcgga
    15781 gaagcagagg attttgtgaa ctttatcagg gaaaaagaca gtatttctgt tacttattat
    15841 ccggagatca acagattcag gggacgagag agtcttcaga ttattattca gaattactgt
    15901 taatattacc gcttggtttg taaccgccgg taagcctgga aatacaaatg tcagggctta
    15961 acagtaactt gattctgaaa taaaaaggtg atatactata aaatatttat gagcgaacag
    16021 caatataaca cacactggag gagaaataaa atgaagaaaa ttgaagatta tgtattaagt
    16081 ataccggatt ttcctgaacc ggggattatt ttcagagata ttacaagtgt tctgcaggat
    16141 gcggatggcc tgcagttggc aatcgactcc atgcaggact gtcttaagga tatagatgtg
    16201 gacgtgattg caggaacaga gtccagaggc tttatctttg gtgtaccgat cgcatataat
    16261 cttcataaac catttgtacc gattcgtaaa aaaggcaaac ttccccgcga aacagtatct
    16321 gtaagctatg atctggaata tggcagtgca gagattgaaa tgcataaaga ttccataaaa
    16381 ccaggtcaga aagtagttat cgttgatgat ctgatcgcaa caggcggtac gatcgaagca
    16441 gcgatcaagc tggtggaaca gcttggcggt gaggttgtca aggttgtatt tctcatggaa
    16501 cttgcaggtt taaagggacg cgaaagactg aatgggtatg atgtagcgtc cgtaatttgt
    16561 tatgatggta aataagcaca gctgattgtg caggacaggc aggtgggagc atatgacaga
    16621 ggtaacaaaa agtacagaag caaaaaaaga tgaaatgcag gttgaaaaag agaagctgga
    16681 atctgtaaag agagcagatg cggcagtaaa gaccatgcat gattttacaa gtccggaggt
    16741 gctttataaa gaactgataa acagtgttct gaagtatcat ccatcaacag atatttccat
    16801 gatagagaag gcatataagg ttgcaagtga agctcatgaa ggacagaaga gaaagtccgg
    16861 agagccatat atcattcatc ctttgtgtgt tgccatcatt ctggcagatc tggaacttga
    16921 caaagaaacg atagttgcag gtcttcttca tgatgcagtt gaagatacct ggatgaccta
    16981 tgaggaagtg gagaaggaat ttggttcaga ggttgcactt cttgtggatg gtgttaccaa
    17041 gctgggacag ttatcttatt ctgcggataa agtagaagtt caggcagaga acctcagaaa
    17101 gatgtttctt gccatggcta aggatatcag agttattctg atcaagcttg cagaccgtct
    17161 tcataatatg cgtaccttac agtatatgcg tcctgaaaag cagcaggaaa aggccagaga
    17221 gaccatggat atttatgctc ctattgccat gcgtctgggt atttccaaga taaaggtaga
    17281 gctggatgac ctgtcgctga aataccttaa gccggatgta tattatgacc tggtgcataa
    17341 ggttgccctg cgtaaaagcg agagagaaca gtttgtaggt gcgattgtaa aagaagttaa
    17401 gaaacatatg gatgatgcca atattaaggc gcaggtggac ggacgtgtaa aacacttttt
    17461 cagcatctac aagaagatgg taaatcagga taagactatt gatcagattt atgatttatt
    17521 tgctgtccgt attcttgtag atacagtgaa ggattgttat gctgcccttg gtgtgatcca
    17581 tgagatgtat aagccaattc cgggacggtt taaagattat attgccatgc cgaaacccaa
    17641 tatgtatcag tcattgcata ccacattgat cggacccaac ggacagccct ttgaaatcca
    17701 gatccgtact tatgaaatgc acagaactgc agaatatggt atcgctgcac actggaaata
    17761 taaggagtcg tctgacggaa aggctcctgt aggtaagagt gaggaagaga aactgaactg
    17821 gctgcgtcag attctggaat ggcagagaga catgtctgat aacaaagaat tcatgagtct
    17881 tctgaagaat gacctggatc tttttgcgga cagtgtttac tgtttcactc cacagggaga
    17941 tgttaaaaca cttccaagcg gttctacacc ggtggatttt gcgtacagtg ttcacagtgc
    18001 agtcggaaat aagatggtag gtgccagagt taacggtaag ctggttccga ttgaatatga
    18061 gatcaaaaac ggcgaccgta ttgaaatcat tacttcacag aattctcagg gaccaagccg
    18121 cgactggctg aaactggtta agagtactca ggcaaagaac aagattaacc agtggttcaa
    18181 gaaggaatta aaagaagata atatccttaa gggcaaggag atgcttgcgc agtatgcgcg
    18241 tgcaaaggga tttaagatcg caaattatac aaaaacccag tatctggagg ctgttttgcg
    18301 taaatatggt ttcagggact gggattcagt acttgctgca attggtcatg gcggattgaa
    18361 agaaggtcag gttttcaata agctggtaga ggcttatgat aaggaaaata agaagaatct
    18421 gacagatgag caggttcttg aggctgcttc tgagacacag gagaagcttc acattgccaa
    18481 gagcaagagc ggcattgtgg taaaaggaat ccatgatgtg gcagtccgtt tttccaagtg
    18541 ctgtaatcca atcccgggtg atgagattgt aggctttgtt acaagaggac gtggaatcac
    18601 aattcatcgt acagattgtg tcaatgtgct gaatatgtct gagacagaca ggacacgact
    18661 gattgaggca gagtggcagc agcctgatac caaggaaaaa gagaagtata cggctgagat
    18721 tcaggtttat gcaaataacc gtacagggct tcttgtggat ctttctaaaa tatttacaga
    18781 acgtaagatc gacctgcgaa gtatcaacag ccgtacaagc aagcaggaga aggcaactat
    18841 ttccatgagt tttgagattg gaagcaaaga ggaactgcgt tccctgatcg agaagatccg
    18901 tcaggtagag agtgtcattg acgtagagag aactacaggc tgatcatgga aaaatctgct
    18961 ggaacattat tttatggaac tgctgcagat tgacagaaag gaataacatg aagaatttag
    19021 aattacagaa atgtatatta ggacctgtat atacaaattg ctatctcctt aagaataaag
    19081 aaaccggaga actgatcatt gttgatcccg cagattgtcc ggagaagatt gaaatgaaga
    19141 tttcccggat gaatggaaaa ccggtggcga ttcttcttac ccatggacat tttgaccaca
    19201 ttctggctgc acaggcagta aaggagaaat ataatattcc gatttatgcc tgtcgtcagg
    19261 aagaggagat gctccgcgaa ccttcgatca atatgactgt acattatgga cagggatgtt
    19321 ctattgtgcc ggatgtattt ctggaggatc tggatgttat cagactggcg ggattttccg
    19381 ttcagatgat ccatacaccg ggacatacca aaggaagctg ctgttattat ctgaaagatg
    19441 aaggtgtatt gttcagcggt gatacagtgt tctatggctc tgttggaaga acggattttc
    19501 cgggtggaag tacagcagaa atcgtgagaa gtctccataa actggtagat tcgcttcctg
    19561 aagagaccga ggttttcccc ggacatgatg catctaccac tattggttat gaaaagaggt
    19621 ataatccatt tgtgtaaaat aggcattctg tttgagaaca gagattttga acatgatgtt
    19681 tatgaactga tcaaagcgtt ttatcccgaa gcggagatac atactcttta tgaaaatgct
    19741 gaagcagagt atgacctccg cttcagtgtg gaacgggata atgacagtta tatcataaaa
    19801 tacgaaagga cagagaatct gtcgaaacag gaaacagagc aaaaaggggt aatttccgca
    19861 gacatacttt ctaaagagaa tgcaggctgt ggaatacagg atgctcatgc tctgagaaaa
    19921 gagaataaag ataatatcaa atatgctttg tatcagttgt tgataaaact gacgggcaga
    19981 actcttccat ggggaaatct gacaggaata cgtcctgcca aactggcaat gggaatgatc
    20041 gaatccggaa tgaaaaatac ggaagcagcc cgggagatgc gtgagagata tctggtaagt
    20101 ccgcagaaaa cagcgcttgc catcactatt gcaaacaggg aaagagagat tctgaaggat
    20161 attgactatg aaaatggata cagcctttat attggaatcc cgttttgccc aagtatctgt
    20221 ctgtattgtt ccttcagctc ctatccgctg aaagtgtggg agaagagaac agatgaatat
    20281 gtggaagctc tctgccggga ggtaagagag actgctctta tgatgaaggg aagaaaactg
    20341 gataccatct atattggcgg cggtaccccg actacactgc ttccacatca gatccgtaag
    20401 ctcctggata cagtgggaga agcttttggc tatgaaggac tggcagagtt tactgtggaa
    20461 gccggcagac cggacagtat tacacgtgaa aagctgatgg cgatcaggga gtatccggta
    20521 acaagaattt ccgtaaatcc acagactatg aatcaggaaa ccctggatat tatcggccgc
    20581 agacatactg tggagcagac aaaagaagcg tttcatctgg cacgagagct gggatacgat
    20641 aacattaaca tggatctgat cgtaggtctt ccgggtgagg atattcacat ggtagagcgg
    20701 actcttgaac aggttcgtga actggcaccg gacagtatta ccgtacattc actggcagtg
    20761 aaacgtgcag caaggctgaa tatttttaaa gagaaatatc aggaaatgtc ttttgagaat
    20821 aatcaggaaa ttatggatct gaccatgaaa actgcgtatg aaatgggaat gggtccttat
    20881 tatctgtaca gacagaagaa tatgaaggga aattttgaaa atgttggcta tgcaaaggtt
    20941 gacaaagcgg gaatttacaa tatactgatt atggaggaaa aacagcctat catcgcactg
    21001 ggggcaggcg gttcttccaa gctggtcttt gaccatggac agagaattga acgtgtggag
    21061 aatgtaaaag acgtttctaa ttatatttcc cgcattgatg agatgatcga gagaaaacgg
    21121 acagcaatag ctacctggct gtaggatgtg gaggtaacat tttggacaca gtacaaaaga
    21181 cagcggcagg ttcacagcag aggatcctgg aatttgacct tgcttctgaa ctgcatcatg
    21241 gaatgctggt aagtaatctg gcttatgcgg ttgcagagga gatgggactg ccgcatgaac
    21301 agtgctatga gcttgcaata gcaggaatgc tccatgatat aggaaagctg aagctgacaa
    21361 gttatattaa cggacaggag caggatcctc tggtgatcga ggaactgaag tatgtccgga
    21421 tgcattctac attgggatat gaggaactta aagggcaggg atattcggat tttgtattgg
    21481 agagtatcct gtaccatcat gagaattatg atggcagtgg atatccgtcc aataaagcag
    21541 gtgatgacat acccataggt gcccggatac tcagagtctg cgatgtata
//
