LOCUS       gnlProkkaAJGMHPLF_62   13921 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJGMHPLF_62.
ACCESSION   gnlProkkaAJGMHPLF_62
VERSION     gnlProkkaAJGMHPLF_62
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:42:55
            Original ID  :: gnl|Prokka|AJGMHPLF_62
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13921
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13921
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7171:9865]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7172..9865
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13921
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13921
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             3..938
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 218.1; E-value: 3.2e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg62_1"
                     /transl_table=11
                     /translation="MKQAIKDACTAYKNFFRGLQKFPRFKSKKRSMPKFYQDNVKIRFS
                     NTHVKFEGFSSSRKANKQKMNWVRLAEHGRIPTNAKYMNPRISFDGLNWWISVCVEFPD
                     CRETLNDDGVGIDLGIKDLAVCSDGTKYKNINKSQKVKKSEKQKRRLQRSISRSYEKNK
                     KGESYCKTNNVIKKEKLLLKRNHRLTNIRKNYLNQTISEIVNRKPRFICIEDLNVSGMM
                     KNRHLSKAVQAQGFFWFRKQLEYRCSDKGIQLIVADRFYPSSKLCSCCGNIKKDLKLSD
                     RVYRCACGNMIDRDFQASINLKTYGEKFAS"
     CDS             1309..1704
                     /locus_tag="ctg62_2"
                     /transl_table=11
                     /translation="MINLGIHAEGQQSQDRLFLYNAGTDSLYLSDFPQSRYFDFSYAPS
                     FDTNTDEEMQPGNCVAVDIVDKKNLPAGKIMVTVKTSPVTGKPAVKLAKVSRQGTKRNV
                     TVTFTVPKSCDGTDWVLPINLLYSNLV"
     CDS             1848..2612
                     /locus_tag="ctg62_3"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTSGGKENSNQTADKKTKVFASSNNAGDVQNSGNDADNTDD
                     SQNTDDSQNTYVDNNSSENNGSTGDGGNQIDQTADQAMIYDSEGNGRLISQADDGNWYD
                     SDGNCYGSWEDIGRAMDEDGVTDQDGNKYYWTWTAPDDASGKVRDPYDLYSWDPGTNSY
                     IPFQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(2755..3642)
                     /locus_tag="ctg62_4"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGAYNTKSMKSVFLSCGFKDVTSSVNLDNGSGMKRGDVLLNIARHTVMHIGNG
                     KVVSASINENGGAHGGTPGDQNGNEIKIQNYYNCPWDCVLRYNEDSTSTDPEPQPTTGN
                     AKIRKGQSYANKFANTGISITGKRDAATKKAAIKVLQTALNKDYGAGLDVDGIWGTNTS
                     NALGKHYVKSGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGLTV
                     SGTCDRNTFLKLIS"
     CDS             complement(3830..4165)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.4; E-value: 4.7e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg62_5"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSLAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             4284..4838
                     /locus_tag="ctg62_6"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             4844..5551
                     /locus_tag="ctg62_7"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKKKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             5555..7036
                     /locus_tag="ctg62_8"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLVVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             7053..7181
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_9"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       7053..7163
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg62_9_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7164..7181
                     /prepeptide="core"
                     /locus_tag="ctg62_9_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[7052:7163](+)"
     CDS             7172..9865
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     760; E-value: 6.5e-230)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_10"
                     /sec_met_domain="DUF4135 (E-value: 7.1e-94, bitscore:
                     304.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-52, bitscore:
                     167.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYIKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDTHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNS
                     RVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPIRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSVGWTGLQFWDNGHWNLRSGGIYLYDGISGTVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVMAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAALYECNHKAEYADKIQLLL
                     KYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKKQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(9918..10442)
                     /locus_tag="ctg62_11"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             10744..10983
                     /locus_tag="ctg62_12"
                     /transl_table=11
                     /translation="METTVMNVAVSHGIWAVLAVFLLVYIVKSNEKRDEKQEEREKNYQ
                     SVIEKLTEKLEILHQVQSDLSEIKENLFGKHKQE"
     CDS             11027..11173
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_13"
                     /transl_table=11
                     /translation="MRFAKLKLRTLYQVEFANSKKYKFQEEMNMVGTMSEKKFICLWIY
                     NGK"
     CDS_motif       11027..11125
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MRFAKLKLRTLYQVEFANSKKYKFQEEMNMVGT"
                     /locus_tag="ctg62_13_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       11126..11173
                     /prepeptide="core"
                     /locus_tag="ctg62_13_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="1842.2"
                     /monoisotopic_mass="1840.9"
                     /core_sequence="MSEKKFICLWIYNGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRFAKLKLRTLYQVEFANSKKYKFQEEMNMVGT"
                     /leader_location="[11026:11125](+)"
     CDS             11163..11282
                     /locus_tag="ctg62_14"
                     /transl_table=11
                     /translation="MGNNVKSDIVVLSKKGKAKNRYRLSEPQYGITYFGKSVK"
     CDS             11557..13671
                     /locus_tag="ctg62_15"
                     /transl_table=11
                     /translation="MKEYKVITALFLSAVMLGTAPLTVWGAESFSTGESFSDGTENIPD
                     IVTDSALSGESSERDYELSIETGTDVELTESDFYDPEFRVEKYVKVRNSGKKETRVRVD
                     ASGLKNFEVDDQMAKWSEDYEEQDSKRLLKPGETLDFFVLPKQEYGTYDETFDFLADDG
                     SRYPVHITMNREKNPTEKKSLEITEKSSESFPIMHWGYKTLPEARIYVLKNFMDMDMEL
                     SFDYSKDCSVSLSGNTSLAPGESTELSLCPQMGLPVGEHDLGVTVTAKTATGETITKKI
                     WDSFRVDSRTFQGLVDTIEPVTGITNGVEKTADALHLPSVLKVYGAEVDGEKTTFSADV
                     KWDVENCAYNPKNTASQSFTVNGQLELREGENNEELDTSVKIKVQVNAYKGLNRPVIDP
                     TWTRVITNYAELSLRDTSNEADGYFFVAAESQKDLEKGNYIAQVKVAKSELNHYPKLKY
                     IPEGTHYLYCRAYKEESGHTEKYGEWSEGFLLKVNIKTPNAPVVQKLQVKKNDVKIILG
                     SNTEELDGYDVVAARSKDGDEPSDYIKVQCRYSGNSKELILKGVPKGNWYIGVHGYKYL
                     DGSNKKVLSKWAEVQKVTVKTSLVTGKPAVKSAKVSRQGTKRKVTVKFTVPKACDGTDW
                     VLAKKVSQSEDGSYTYVSGYAYTKKNQTKTTVIFKNVKPGVYYLTGRAYVKGYAKNYTK
                     WSEVKKVVVK"
ORIGIN
        1 taaccaaaca ggcgatcaaa gatgcctgta ctgcttataa gaactttttc aggggcttgc
       61 aaaagttccc aagattcaag tcaaaaaaga gatcaatgcc gaagttctat caggacaacg
      121 ttaagatacg cttcagtaat acacacgtta aatttgaagg cttttcttcc agcaggaaag
      181 caaataaaca aaaaatgaat tgggtaagac ttgcagaaca tggacgtatt ccgacaaatg
      241 ctaaatatat gaacccgaga atatcctttg acggattgaa ctggtggatc agcgtatgtg
      301 tagaatttcc tgactgcagg gaaacactta atgatgacgg agtcggcata gacctgggaa
      361 tcaaagacct ggctgtctgc tctgatggga ctaagtataa gaacatcaat aagagtcaga
      421 aagtaaagaa atcagaaaaa cagaaacgca gattacagcg tagtatctct cgttcttacg
      481 agaaaaataa gaaaggggaa agttactgta aaacaaataa tgtaatcaaa aaggaaaaac
      541 ttttattaaa acgaaatcac agattaacaa acatccgtaa aaattattta aatcagacca
      601 tatcggagat cgtaaatcga aaaccaagat ttatatgtat tgaagatctg aatgtcagcg
      661 gaatgatgaa aaacagacat ttatccaaag cagttcaggc acagggattt ttctggttta
      721 gaaaacagct tgaatataga tgcagcgata aagggatcca gcttattgtg gctgatcggt
      781 tttatccatc ctcaaagctt tgcagctgtt gtggaaacat caaaaaagat ctgaagttat
      841 ctgacagagt ttatagatgt gcgtgtggga atatgattga cagagatttc caggcatcta
      901 taaatctcaa gacttatgga gaaaaatttg caagctgaca ctgaaatgtt aatgcaaata
      961 tgtacggata cgttagtccg gaatttacgc ctatggagag tacaagaact tgtgagtaga
     1021 ttgatattta tattatcaaa agcatactcg ttgaagtagg aatggaacat aaaagtttat
     1081 aactttttat aagttttcag taacggagaa gaatgaaaag taattacaaa atttttacag
     1141 cagtttttta tcggcaatta tgacagcagc agctccgtta acagtatgtg gggcggaagt
     1201 tttttcgtcg ggagaatctt tcagtgatgg aacggggagt attcctgcca tattgacaga
     1261 tatggttctg ccgggtggag agattggaac ggaatatcag gtacagcttt gatcaatctg
     1321 ggaattcatg cagaggggca gcagtcacaa gatcgcttat ttctttataa tgcaggaaca
     1381 gattcacttt atctttctga ttttccgcag agcagatatt ttgacttttc ttatgcaccg
     1441 agtttcgata cgaatacaga tgaagaaatg caacccggaa attgtgttgc cgtggacatt
     1501 gttgataaga agaatctccc tgccggaaaa attatggtaa ctgtaaaaac aagccctgta
     1561 acaggaaaac ctgctgttaa attagctaag gtttccagac agggaacaaa aagaaatgta
     1621 acggtgacgt ttactgttcc aaagtcctgt gatggaacag actgggtact gccaataaac
     1681 ttattatact caaatcttgt ctgaatttgg agataaataa tgtccttttt atgacagata
     1741 agggacatat gaggcatcaa agcctgtgga gtatgtaata atgaacagga aaagcacatt
     1801 atgataaagg cagtgacatt tttagcaaat gtagaaagga caacaaaatg aagcagaaaa
     1861 agattgtaat tattatggca gggattttag cagcagcggc tgctatgact ggctgtgcgg
     1921 aacagaataa aacagcgaca caggttgatt atacgcagaa ttcacagggg aaatccgaac
     1981 agacaaaaca aaaaacagca gaaaaatctc agccggataa aaaacaggta aataaaagta
     2041 catccggtgg aaaagaaaat tcaaatcaga ctgcggataa gaagacgaaa gtatttgcct
     2101 catccaataa tgcgggcgat gtacagaatt cagggaatga tgcggataat acagatgatt
     2161 cacagaatac agatgattca cagaatacat acgtggacaa taattcatct gaaaataatg
     2221 gctcaacagg cgacggtggc aatcaaattg atcagacagc agatcaggcg atgatatatg
     2281 acagtgaggg aaatggaaga ctgatttctc aggctgacga tggaaactgg tatgacagtg
     2341 acggaaattg ttatggaagc tgggaggata ttgggcgtgc tatggatgaa gatggtgtta
     2401 cggatcagga tggcaataaa tactactgga cctggaccgc acctgatgat gcatcaggaa
     2461 aagtaagaga tccgtatgac ctgtattcct gggatccggg aaccaattcc tatataccgt
     2521 ttcaggctgc ggaatctgac tgtagtccta taggcagagg aaacggctgg tattattatg
     2581 atgaagacag cggcgaatat gttccgtggt aaaaaataag aaaacaaaag aaacagtttt
     2641 gaaatcattt tgatgggttt caaaactgtt tctttttata tacaagaaat agtgaagggg
     2701 catatccggc agaatcagtg aaaagaattc tgccggatgt ttatctggta aagatcagct
     2761 gatcagtttc aggaaagtat ttctgtcaca ggttccggaa accgttaagc cctgtgcctt
     2821 ctggaatgcc tttacagcag agagaagtcc tgagccaaag gtaccgggaa tctctacacc
     2881 gtttggatca taagcacgta aaagaaggag aatctcagcg gcagttacca tatactgggt
     2941 ttcaccgctt tttacgtaat gtttaccaag ggcattgctt gtgttagttc cccagatacc
     3001 gtctacatcc agaccggcac cataatcttt gttcagagct gtctgaagaa ctttaatagc
     3061 tgctttctta gtggcagcat ctcttttccc ggtaatggag atgccagtat tggcaaattt
     3121 attggcataa ctctgacctt tgcggatttt ggcatttcca gtagttggct gtggttctgg
     3181 atccgtagat gtagaatctt cattataacg aagaacacaa tcccacgggc agttgtagta
     3241 attctggatt ttaatttcgt tgccattctg gtcacccgga gtaccaccgt gggctccacc
     3301 attttcattt atactggcag aaactacttt gccgttgccg atatgcataa ctgtatggcg
     3361 tgcaatgttt aacagtacat caccgcgttt cataccgctt ccgttgtcaa gattaacact
     3421 ggaagtaacg tctttgaatc cgcaagacag gaaaacagac ttcatacttt tggtattata
     3481 agctcctttt gtttttacag gtacaccagc ctgctgccat gcagagatta ccagtgaaga
     3541 acaatcgtag tccggtcccc atctgttatc ctgatcatat ccgtgtgccg gatcgtttgc
     3601 gatttcaatt gcccatgtta ctgctttttc tgtttttgtc atttttttat cctcctgaaa
     3661 tttgattatt tatttgctca ccggtgatac atcttataaa gagtgagaaa agggaaaaat
     3721 gtaaacatga aacagaaaaa aataaaaagc atttcctgat tgttgcttcg aggtcagaaa
     3781 aatgcttttc gaggacaaaa acacgaaaat tgtcgaattg taattatatt taatcctgat
     3841 gagaggcctg gtatattttc agtattttta caatgtattc agtctggcgt tcacccattt
     3901 gattcatgat tgaaatcgca tcctgaatag ccaggctttg aatatcttta ttatgaggaa
     3961 gcagatcata aagaaaatag tcaagtccca catcaagaat ttcagaaagc ttaaggagat
     4021 tttcaatagt aggcatatac ttacctgttt caatccggct gatcgtactt acagataaac
     4081 cacttaattc ttccaggtgt tcctgggtaa tatttctgtt gatccgagct tctgcaattc
     4141 tttttccgat agtattgttt ttcataaata aaaatccttt cctttgataa agtttaacag
     4201 acggaattaa atatgtataa ggatataaat gacaagcgac taatcaaatt tgatatgttt
     4261 tatgacagga ggaatatagg aatatggacg aatatacaaa ggatttgtat accatgatgt
     4321 tttctttgca gactttgcaa aatcagggaa ttacaatcag agaaactgta tataaaagtc
     4381 tggacaaatt actgttatgg aataaagaat ctgaaaacag taaatatctc gaattagcgt
     4441 tgcttcatat gcaggcttat gctaatatgg gatttgcttt agatgaagaa aataagacaa
     4501 tacgtgagat attaaaaaag acaggaaaga ccagagaaga ctttttcccg aaaggatatc
     4561 ttcttggaaa gagaattaaa ctgaccaagt cacaggttcg tggtatgatt ggaagatgga
     4621 gaccttccag agacagtccg atgacaatcg gagaactggt ggatgatatc atcagaaagg
     4681 taaaaaacca tgaggaaggc agatacattt atcagtatca cagaactgat gtgacaacca
     4741 aaggggatat cgaggtttat gagctggtca tcaataagga tgaaagttat ttttatgatg
     4801 tgaagaaatt cagattttat acattcatgg aggaataatt gctatgataa gaataatgat
     4861 tctggatgat gacgaaatgt atctgaaaaa agaaaaggat atcacagaac agtattttgc
     4921 agagaaaaac gtagattgca cggtaacgat ataccagaat gtggaatggt ttctgctggg
     4981 attgaatgaa gaaaaattcg atatgtatat tctggatatc cggatgcctg gagaaaacgg
     5041 aatagaggca gcgagggaaa ttcgcagact ttatccggat ccggttatta tatttattac
     5101 aaattttgtg gattatgcaa tagaagcata tgaggtaaac acctatcgtt atatccccaa
     5161 agagtgtctg aagaaaaaac ttccgcaggc ttatgatgcg cttcttcctg gaattatgga
     5221 gaaagaagag cggtactata tcataaataa aagaaatgaa gttgaaaaac tggcatattc
     5281 tgatattttc tatatgaaaa aagaaggaaa atatgtcatt tttgtgcaca ggcgtgggga
     5341 agtaaagatc agagcaagtc tgtcaacagt agaaaaggaa ctgaattcaa aagaatttat
     5401 tatatctgac agaggatatc ttgcaaacat ccaacatgtg atgaagatga aaggaaggga
     5461 tctttatatg cgggacggta atattattac agttggcaga gaaagattca aaggtgtcag
     5521 agaagcaatt ctgaattact ggggggtatg aagaatgctg aaagttttat tgtatggact
     5581 ggcaacgttt atggagacag ggataggtgt ctggatattt agccagacgt tttctgaacg
     5641 aagaatatta gaaaaaaaat attatgttct agaatggctg ttgtattctt tgattttttt
     5701 tggaatttat aatttttctg tttcattatg gcagattgat aaaaaaatag aaaaatatgt
     5761 cataaaagtt atttgtatat acataattgg attaattgca ggaattatat atgatatttt
     5821 ttttgtaaag aaaaaggaga tggtcttaag aagaatatta tatatcggca tgatattttg
     5881 gttaactgct cagtattggg ctggatatca atcgttgtta atgattattc ttgggagtgg
     5941 aataattgta ttatatgttt tttgctactt tgattgcaca tttaaacagg catatgtttg
     6001 gaattttttc tatgcagtta atataggatt gataaaagag gcttatgttg tatatgcagg
     6061 ggtgtttaac cataaacagt gggatgattt ttattcatat ccgagaggac atacatatca
     6121 ggaagttata ttttggattt taggctgttt attcatattt tggataatta aatttatttt
     6181 gtcagtaaac agtataaaag gaatattgcg tacacgtctg aaggaacttt ttattattgg
     6241 attgttagag tatgttttat taatagttag catcatatac aaatttggta cgattaaaaa
     6301 ggaaaatttt gtaatgaccg catgtttatt agtagttagt aatatagcat tgattggtgt
     6361 atatgttaag tttcaaaaaa agaccctaga aatgagaaat cagattttag atatgagatg
     6421 caaattaatg gaagaagaat atgaagaatt gagaatgtca tatgaccggt atcggtgttt
     6481 ggtgcacgat gaaaaacatt tgcttttata tataaaagaa tgcctggaaa atggagaact
     6541 ggattcatgt atcacttttt tgaatcatta caagagagaa agcattagat atagtggagt
     6601 agcgtggaca ggaattccag aaataaattt tatgttgaat ataaaagtgc gaaaaatgga
     6661 agaaaagaat atttttttta aagtagattc aaaaatagaa aaaattccga tgaaagacat
     6721 agattttgtt gtactcctag gaaatctttt ggataatgca atagaagctg ctgaaaagtg
     6781 tgaagaggga aaaggtaaaa ttacgtgtat ttttcgaaat attaatgata tgtttatttt
     6841 taaagtaaag aatacaagca tatataaacc ttatgaaaaa aacactaaat tttatacaag
     6901 taaaaaagag aaagatgagc acggatgggg gattgaaagt gtcaaacaaa ttgtaagaaa
     6961 gtataatggt gaaatagatt ttaaatatga taaagatttt tttgaagtag aaataataat
     7021 tagcgataat acataatggg agagtgacgg ttatgaacga aatgaatgat aaaataatag
     7081 gaaatgtgga aaaagaatta gatgaaatag agataataga tacggaaagt atagaagaga
     7141 aattgtcttt tattgtatat ggaactatag tgtgttgctg aaattggatt atttatgcag
     7201 aaaaaatcga actatgtttc ttaaaatatt aatcttagat gtacatcggc agaaaaattt
     7261 tggaaatcta aaaggaagta cgccaaaaga acaatatgat tattatgaaa aaaaatatct
     7321 taacaatgca acatatataa aatctttact gcaggaatat cccgagttaa aacgtctgct
     7381 tgaattaaaa aataactcta tccagagagc agaatgtgaa atcaggaaat ctctttatgc
     7441 agaaaaagaa cagatacaaa aaatattctg tgatggaaga aagttttccg ggactgtggg
     7501 aatttacatg tcgaaaggcg atacacacag aggaggacga agtgtggcaa aggtagaatt
     7561 ggataatgga acaattctgt actataagcc acatagtctt gataagaata taaaatatca
     7621 ggaactttat aactatttat gcagaaaaac aggaatttcc tgcaggacgg tacaatattt
     7681 atctcatgat tcctatggat gggaagaaaa aattgagaat attccctgta aaaacgaaag
     7741 cgaggtggag cattattatt tcagaatggg catacatctg tttttgggat atgcccttgg
     7801 agcaacagat cttcatggtg aaaatattat cgcacatgga gaatatcctg tgattatcga
     7861 tatggaaacg tatccgggat atttaaaaca acaatcagaa aaagacggaa gtagtgtaga
     7921 agaaaaaata aacaaaagta cagaaataaa attggcaaat tcggttatac atacaggaat
     7981 gctccctgtt ctcacatggg gcagaggaaa cagcagagtt cttataagtg caatgggaac
     8041 agaggaaaag ataaaaacgc cgtttaaact tcctgtggta aaggatgata aaacatctga
     8101 tattcacata gaatatgaac ctgtggaaat gcagataaag gaatgcattg taagactaaa
     8161 tgatcaggtt atcaatgcgg cagattatac ggaatgcatt atcagaggat tttgcagagc
     8221 gtacatggtg acaatggcag ataagaaagt ggaggtgatg ttgtccggct tttttgacgg
     8281 acgttccaga gttgtactgc ggcataccca acagtatgca atgtatctta tggcttcgtt
     8341 tcatccggat tatatgaagt caagggaatg caggaaagct cttttgaatg tgattcacaa
     8401 agagggggaa tcttctttta tgaaagagat tcatgattat gaaattgaca gccttctgga
     8461 aatggatata ccctgctttg agattgatgc gaacagcaga tctgtttatg atggaaatgg
     8521 cggagaacat aaagaatatc tgccctgtac tccttatgag tcatggcgaa tgcatatgaa
     8581 gcagatgagt tactctgata tggaatgtca gtgtgattat atcaggctgt ccatggaaat
     8641 gctgaaggca tctgatggaa agaaaaagat gtttccgatc aggataaagg gatatgacac
     8701 agataaagag cgcaaaatat acagtcagat cagaaagata gttcatcgaa tctgcagcag
     8761 agcgattatc cgggaacaga gtgttggctg gacaggactg caattctggg ataatggtca
     8821 ctggaacctc agatcaggtg gaatctattt atatgatgga atatcgggga cagtcttgtt
     8881 tcttgcaaaa tatcttcatg attttgaaga aaagaatgca agtgcagaag aaatttatca
     8941 tcttgctgtt ttgagattga aagcttatac agatgaaata cacaaaaaac agatttatga
     9001 taaaaatctt ctgacaggta ttgtaaatgg agaaagctcg gtggtatata cctatcttta
     9061 tctgtttaaa cttacaggaa aaagagtatg gatgatttat gcggaaaagc atttcagcat
     9121 tattgagagg gtatggaaag aagattcaca actggattat ctgagcggaa atgccggagc
     9181 tattgtaatg gcagtaatgt tatataaaga aaccggaaat ctgaaatatt atgaaatagc
     9241 ggcagatatg gaaaaagatt tgtggaagaa aggacaggaa accggaaatg gatacggatg
     9301 gagattaaaa ggaacagacg gaccgctggc tggaatgtct catggcaaca gtggatttat
     9361 gatggcttat gcagcgttgt atgaatgtaa tcataaagcg gaatatgctg ataaaataca
     9421 gcttttgctg aaatatgaag attctctgta ctcagagaaa gccggaaact ggaaggattt
     9481 acgagagagt tcaggggaaa gcttcatgaa tgcatggtgc catggggcgc cgggaatcct
     9541 gctttcacga atgaaactgg aggagctgtt tcctgaggat atgcagatta aaaaagacag
     9601 gttaaatgct gcagactctt tgttttatgg agaacaggat gaaaaaattt gtctgtgtca
     9661 tgggatgtcc gggaatttac ttattatgaa gaagtacctt cgaaaatatg gtaataaaaa
     9721 aatgaagaag caatatgagg cgttatgtga ctgcctttta tttcaactgg atcacccggc
     9781 aaaaatatct gggacagaat atctgaatct ggcttttatg aatggcattt ccggtacggg
     9841 aatggcatta atggaaattt tatgaaaact aagggaacac ctgcagactg taaatttatg
     9901 gtcagcaggt gtttctttta tttgttttcg gaaatatatc tgagaattag tttcttcttc
     9961 atccgattga cgtactggcg ggacagcttc agtttccggg caatctgggc atcgctttta
    10021 tcctgataaa agtacatgga cagaattttt ctctggacac tgtccgaagg gtaagagttg
    10081 atatatgcgg ttacatcata ataggtgtca tcaaaactgt cgggagcctg taatgaaaca
    10141 gaacaagaat caaaatcatc tttttcaggt tcggaaagac aactgcggca aagggaacga
    10201 tatctgtttt cgacagaggt ctgcatgtat ctgatacatt caccttctga ggatgaagaa
    10261 cttaaatatg gcaatgtctt taacagagta agatacaatt cctgtgtgga atcttcacgt
    10321 tccatgcagt gaatccggga tgcatatcct ttcacaagcg gttccatacg tttgagaatt
    10381 tcactgtctg aatctgggat accattttga taattttgga taagttctgt cagtgttttc
    10441 atagttatct acctcctttt taggggaagt agtaagaaaa ctgctgatca gaaactaaaa
    10501 aagaaaaaaa ttgtgagttt acaaatggaa gagaaaaaac tctttattaa gtgagtttgc
    10561 aaattcaaat taatgataag aggagaaaaa atatatggta aaaagagatt ggtagaataa
    10621 ttgtagagaa taaaactgtg ccttaaattg gaacggtaat aataagacca gaaaagactt
    10681 ttagtggatg gaatatagaa aaaaatgcgt aataaaagaa gattaagagg agggaggtga
    10741 actatggaaa caacggttat gaatgtggca gtttcacatg gaatctgggc agtgctggcg
    10801 gtatttcttt tggtttatat tgtgaaatca aatgaaaaac gagatgagaa acaggaagag
    10861 cgggaaaaaa attatcagtc tgtaatagag aaactgacag agaaattaga gattttacat
    10921 caggtacaaa gtgatttatc agaaatcaaa gagaatcttt ttggtaagca taagcaggag
    10981 taaaaattca gatataaaat aaaattgtca aaggaaaatt tattctttga ggtttgcaaa
    11041 gctgaaatta agaactcttt atcaagtaga atttgcaaat tcgaaaaaat ataaatttca
    11101 ggaggaaatg aatatggtag gtacaatgtc agaaaagaaa tttatatgtt tgtggatata
    11161 caatgggaaa taatgtgaaa tcagatattg ttgtattatc aaaaaaaggt aaagcaaaaa
    11221 atagatatcg tctttctgag cctcagtatg gaattacata ttttggaaaa tcagtaaaat
    11281 gatatgagtt cattttaatg aataaatggc atgaggatga aggcggcatt gaaagtgaaa
    11341 aaatcttttt gataaaatag gaaaaaaata agaaaaagaa atagaagctc tctctacaaa
    11401 atgaatgtta cagtagggag agcttttgtc attcaggtaa gaaaatagat tataacattc
    11461 atgcccatta gaatacgttt tattctataa ttacagatgt ttatataaat ggtgatatac
    11521 tatgataata aatatcattg aatggaggaa aaagagatga aagaatacaa ggttataaca
    11581 gcactttttt tgtcagcagt aatgctgggt acagctccat taaccgtatg gggagcggag
    11641 agtttttcga caggggaatc tttcagtgat ggaacagaaa atattcctga catagtaaca
    11701 gattcggctc tgtctggtga atcctctgaa agagactatg agttaagcat agaaacaggt
    11761 acggatgtag agcttacaga aagtgatttt tatgatccgg aatttcgtgt agagaaatat
    11821 gtgaaagtca gaaattcagg aaaaaaagaa acaagagtcc gggtagatgc ttctggtctt
    11881 aagaattttg aggtagatga tcagatggca aagtggtcag aggattatga ggaacaggat
    11941 tccaaaagac tgctgaagcc gggagaaact ctggactttt ttgtactgcc aaagcaggaa
    12001 tacggaacat atgatgaaac gtttgatttc cttgcagatg acggaagcag atatccggtt
    12061 catatcacaa tgaacagaga gaagaaccca acggaaaaga agagtctgga aattaccgaa
    12121 aaatcttccg agagtttccc gataatgcac tggggatata agacacttcc ggaagctaga
    12181 atttatgttt tgaaaaattt tatggacatg gatatggaac tgtctttcga ttatagcaaa
    12241 gactgtagtg tatcattatc cggaaatacc agtctggcac ctggagagag tacagaactg
    12301 agcctttgtc cgcagatggg actgccagtt ggagaacatg atcttggagt gacagtgact
    12361 gcgaaaacag cgacaggaga gactataaca aagaagattt gggattcttt cagagtagat
    12421 tcaaggacat ttcagggact ggtggatacc attgaacctg tgaccggaat taccaatggc
    12481 gtagaaaaaa ctgctgatgc tttacatttg ccatcggttc ttaaagtcta tggtgctgaa
    12541 gtggatggag aaaaaacgac attttctgcc gatgtaaaat gggatgtgga gaattgtgca
    12601 tataacccga aaaatacggc gtctcaaagt ttcacagtta acggacaatt ggaactgcgt
    12661 gaaggtgaaa acaatgaaga gctggatacg tctgtaaaga taaaggtaca ggtgaatgcg
    12721 tacaaggggt tgaacagacc ggtgattgat ccgacatgga ccagagtgat cacaaattat
    12781 gcagaacttt ctttaagaga tacttctaat gaagcagacg gatatttttt tgtagcagca
    12841 gaatctcaaa aggatctgga aaaaggaaat tatatcgcac aggtgaaggt cgcaaaatct
    12901 gaactgaatc attatcctaa actgaaatat attcctgaag ggacgcatta tctctattgc
    12961 agggcatata aagaggaaag tggtcatacg gagaaatatg gtgaatggtc tgaaggattt
    13021 ctgttaaagg taaatataaa gacaccaaat gcacctgtgg ttcagaaact gcaggtgaag
    13081 aaaaatgacg ttaaaattat ccttggcagt aatacagaag aactggatgg ttatgatgtt
    13141 gttgctgcca gaagtaaaga cggggatgag ccatcagatt atataaaggt acaatgcaga
    13201 tattcaggaa acagcaagga actcattcta aaaggagtac cgaaaggaaa ctggtatatt
    13261 ggtgtacatg gctataaata tctggatgga tcaaataaaa aagtactgag taagtgggcg
    13321 gaagttcaaa aagtaacggt aaagacaagc cttgtaacag gaaaaccagc tgttaaatcg
    13381 gcaaaggttt ccagacaggg aacaaaaaga aaagtaacgg tgaagtttac tgtaccaaaa
    13441 gcctgtgacg gaacggactg ggtactggca aagaaagtat ctcaatctga agatggaagt
    13501 tatacatatg tcagcggtta tgcttatact aagaaaaatc agacgaaaac tacagtcatt
    13561 tttaaaaatg taaaacctgg agtttattat cttacaggac gtgcttatgt aaaaggatat
    13621 gcaaaaaatt atacgaaatg gtcagaggta aagaaagtag ttgtgaagta gaaaagtgat
    13681 ttagaccaga aatttaattt ttttctgcat atatatcaaa aagaatgttc ttatagtagt
    13741 attattaaaa atccccctta gacagagtaa aggaaactgt ttaaggggga tttttataat
    13801 gaggtatctt attggtatct aatgaatgac ttatgagaga ggacttaaat catgaaaaat
    13861 attagattat gctggattgc ggcttctctg ttttgtcatt ttttcatggt gttttttcta
    13921 c
//
