GCA_959608895.1 - 6 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaAJGMHPLF_1 (original name was: gnl|Prokka|AJGMHPLF_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	ranthipeptide	156,697	197,463

gnlProkkaAJGMHPLF_6 (original name was: gnl|Prokka|AJGMHPLF_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	lanthipeptide-class-ii,ranthipeptide	1	32,139	ruminococcin A	RiPP:Lanthipeptide	14%

gnlProkkaAJGMHPLF_21 (original name was: gnl|Prokka|AJGMHPLF_21)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	ranthipeptide	273	21,861

gnlProkkaAJGMHPLF_27 (original name was: gnl|Prokka|AJGMHPLF_27)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	NRPS	16,961	52,968	dipeptide aldehydes	NRP	47%

gnlProkkaAJGMHPLF_52 (original name was: gnl|Prokka|AJGMHPLF_52)

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	cyclic-lactone-autoinducer	1	15,425

gnlProkkaAJGMHPLF_62 (original name was: gnl|Prokka|AJGMHPLF_62)

Region	Type	From	To	Most similar known cluster		Similarity
Region 62.1	lanthipeptide-class-ii	1	13,921

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	ranthipeptide	156,697	197,463
Region 6.1	lanthipeptide-class-ii,ranthipeptide	1	32,139	ruminococcin A	RiPP:Lanthipeptide	14%
Region 21.1	ranthipeptide	273	21,861
Region 27.1	NRPS	16,961	52,968	dipeptide aldehydes	NRP	47%
Region 52.1	cyclic-lactone-autoinducer	1	15,425
Region 62.1	lanthipeptide-class-ii	1	13,921

Compact view

gnlProkkaAJGMHPLF_1 - Region 1 - ranthipeptide

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Location: 156,697 - 197,463 nt. (total: 40,767 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAJGMHPLF_6 - Region 1 - lanthipeptide-class-ii,ranthipeptide

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Location: 1 - 32,139 nt. (total: 32,139 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg6_7

ctg6_6

Leader:

MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS

Core:

QFCTSTKECNWGTIMFVCC

Core with dehydrations:

QFCysDhbDhaDhbKECysNWGDhbIMFVCysCys

MIBiG 3.1 matches for ctg6_6

26.3% BGC0000503 (cinA): Lanthipeptide: cinnamycin

7

KECNWGTIMFVC

18

+ C++G FVC

3

QSCSFGPFTFVC

14

20.0% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

2

FCTSTKEC

9

+CT TKEC

18

WCTLTKEC

25

17.9% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

2

FCTSTKEC

9

+CT T EC

16

YCTLTVEC

23

with 3 more sequence matches

13.6% BGC0000553 (SSGG_RS09925): Lanthipeptide: SRO15-2212

9

CNWGTIMFVCC

19

C + ++ V C

10

CEYSSLSVVLC

20

12.8% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

3

CTSTKEC

9

CT +KEC

28

CTLSKEC

34

10.8% BGC0001229 (SBI_06989)and 1 other:

BGC0002110 (QKV49894.1) Lanthipeptide: birimositide

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

2

FCTSTK

7

FC +TK

27

FCPTTK

32

antiSMASH-DB 4.0 matches for ctg6_6

100.0% NZ_CP102267.1and 11 others:

NZ_FMUW01000051.1 Lanthipeptides: BLP57_RS16830_lanthipeptideNZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07130_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: PGR68_RS13915_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: PG840_RS15980_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: PG808_RS00050_lanthipeptideNZ_LN913006.1 Lanthipeptides: BN3261_RS01470_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: DWZ74_RS14610_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03120_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06255_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03580_lanthipeptide

Lanthipeptides: NQ550_RS04155_lanthipeptide

1

QFCTSTKECNWGTIMFVCC

19

QFCTSTKECNWGTIMFVCC

1

QFCTSTKECNWGTIMFVCC

19

42.9% NZ_QRHZ01000008.1and 2 others:

NZ_QSRF01000021.1 Lanthipeptides: DXC87_RS15310_lanthipeptideNZ_QUEQ01000033.1 Lanthipeptides: DXA48_RS19000_lanthipeptide

Lanthipeptides: DW272_RS13830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

FCTST ECN GT+ CC

11

FCTSTGECNMGTLNIFCC

28

40.0% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT FVCC

7

TATSECYLGTFAFVCC

22

with 18 more sequence matches

40.0% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide

1

QFCTSTKECNWGT--IMFVCC

19

QF T + EC+W T +F CC

4

QFDTISHECHWNTWQFLFTCC

24

36.0% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT F CC

7

TATSECYLGTFAFACC

22

34.6% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT+ F+CC

7

TATSECYLGTVAFICC

22

33.3% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

3

CTSTKECNWGTIMFVCC

19

CT T ECN GT + CC

12

CTLTGECNIGTHIKFCC

28

29.2% NC_012470.1and 42 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08895_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02930_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFTCC

24

29.2% NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFSCC

24

27.6% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

1

QFCTSTKEC

9

QFCT TKEC

15

QFCTLTKEC

23

26.3% NZ_CP059557.1: Lanthipeptides: H2Q94_RS19875_lanthipeptide

7

KECNWGTIMFVC

18

+ C+WG + VC

3

QSCSWGPVTAVC

14

25.0% NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

1

QFCTSTKEC

9

Q+CT TKEC

15

QWCTLTKEC

23

24.1% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

1

QFCTSTKEC

9

+FCT TKEC

15

RFCTLTKEC

23

21.6% NZ_CP016767.1: Lanthipeptides: BCV50_RS18735_lanthipeptide

1

QFCTSTKECNWGTI

14

Q+CT + EC +GTI

21

QYCTVSAEC-FGTI

33

20.6% NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

1

QFCTSTKECNWGTIM

15

+ CT T EC TI+

18

RLCTGTAECPIMTII

32

19.2% NZ_CZAY01000009.1and 12 others:

NZ_CZBA01000009.1 Lanthipeptides: ARA06_RS08755_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: ARA29_RS04330_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: I4V06_RS02990_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: OCV99_RS00835_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: PGZ10_RS13865_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: PHA23_RS12680_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: DWV87_RS01465_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: DXB81_RS03120_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: DW648_RS14740_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: DXB83_RS07060_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: DXB71_RS08970_lanthipeptideNZ_SLZV01000043.1 Lanthipeptides: EDD74_RS14380_lanthipeptide

Lanthipeptides: ARA07_RS06830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

CTST EC +GT++ CC

32

LCTSTAECYFGTLLKPCC

49

17.5% NZ_CM001792.1and 1 other:

NZ_CM001792.1 Lanthipeptides: C794_RS17980_lanthipeptide

Lanthipeptides: C794_RS17980_lanthipeptide

2

FCTSTKEC

9

FCT TKEC

26

FCTITKEC

33

17.1% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide

Lanthipeptides: BUE45_RS13060_lanthipeptide

1

QFCTSTKECN

10

+FCT T ECN

26

RFCTVTVECN

35

16.7% NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

1

QFCTSTKEC

9

++CT++KEC

16

KYCTASKEC

24

15.8% NZ_BMRY01000003.1and 28 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12370_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18205_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptide

Lanthipeptides: IE140_RS12370_lanthipeptide

1

QFCTSTKEC

9

FCT+T EC

25

NFCTATAEC

33

14.7% NZ_CAKMMP010000011.1and 5 others:

NZ_CP018620.1 Lanthipeptides: BS614_RS05680_lanthipeptideNZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptideNZ_FMVM01000006.1 Lanthipeptides: BLQ13_RS10365_lanthipeptideNZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: L6H98_RS19925_lanthipeptide

2

FCTSTKECNWGTI

14

FCT + EC++ ++

13

FCTVSHECHYNSV

25

allorf_01766_01864

Leader:

MIRSSIIFFVLNKLQGS

Core:

CQVSVRFLSEKYIIL

Core with dehydrations:

CysQVDhaVRFLDhaEKYIIL

antiSMASH-DB 4.0 matches for allorf_01766_01864

100.0% NZ_CP102267.1and 7 others:

NZ_JAQDBP010000004.1 Lanthipeptides: allorf_177044_177142_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: allorf_20164_20253_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: allorf_02084_02182_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: allorf_017059_017148_lanthipeptideNZ_LN913006.1 Lanthipeptides: allorf_0097924_0098022_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: allorf_103379_103477_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: allorf_092199_092297_lanthipeptide

Lanthipeptides: allorf_0889319_0889417_lanthipeptide

1

CQVSVRFLSEKYIIL

15

CQVSVRFLSEKYIIL

1

CQVSVRFLSEKYIIL

15

allorf_17088_17240

Leader:

MVISLHYIIGS

Core:

FTYTVRTEYVFILGEVRCTYCVSIGYCQRKVYGYKKSTD

Core with dehydrations:

FDhbYDhbVRDhbEYVFILGEVRCysDhbYCysVDhaIGYCysQRKVYGYKKDhaDhbD

MIBiG 3.1 matches for allorf_17088_17240

7.7% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

20

YCVSIGYCQRK

30

+C CQ

18

WCTLTKECQPN

28

antiSMASH-DB 4.0 matches for allorf_17088_17240

100.0% NZ_CP102267.1: Lanthipeptides: allorf_0904640_0904792_lanthipeptide

1

FTYTVRTEYVFILGEVRCTYCVSIGYCQRKVYGYKKSTD

39

FTYTVRTEYVFILGEVRCTYCVSIGYCQRKVYGYKKSTD

1

FTYTVRTEYVFILGEVRCTYCVSIGYCQRKVYGYKKSTD

39

20.5% NZ_CP011129.1: Lanthipeptides: allorf_3545239_3545370_lanthipeptide

4

TVRTEYVFILGEVRCTYCVSIG

25

T+ T + F RC C S G

5

TLATAHAFDQSRRRCKTCESRG

26

15.4% NZ_CP013140.1: Lanthipeptides: allorf_2670844_2670996_lanthipeptide

18

CTYCVSIGYCQ

28

CT CV G C+

10

CTPCVRAGACR

20

with 1 more sequence matches

12.8% NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27195_lanthipeptide

Lanthipeptides: EXW52_RS27195_lanthipeptide

21

CVSIGYCQRKVY

32

+S+G C K+Y

17

AISVGLCPTKMY

28

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg6_6 - Class II

Cleavage pHMM score: -6.40

RODEO score: 0

Monoisotopic mass: 2127.9 Da

Molecular weight: 2129.5 Da

Number of bridges: 4

allorf_01766_01864 - Class II

Cleavage pHMM score: -5.20

RODEO score: 0

Monoisotopic mass: 1761.0 Da

Molecular weight: 1762.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1780.1 Da N = 1

allorf_17088_17240 - Class II

Cleavage pHMM score: -4.00

RODEO score: 0

Monoisotopic mass: 4512.3 Da

Molecular weight: 4515.2 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4533.2 Da N = 1; 4551.2 Da N = 2; 4569.2 Da N = 3; 4587.2 Da N = 4

gnlProkkaAJGMHPLF_21 - Region 1 - ranthipeptide

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Location: 273 - 21,861 nt. (total: 21,589 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAJGMHPLF_27 - Region 1 - NRPS

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Location: 16,961 - 52,968 nt. (total: 36,008 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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other genes

resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 16960 - 52968:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg27_38

AMP-binding (691..1082): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAITTGGVSK
Nearest Stachelhaus code(s):: Leu or Trp DAITTGGVSK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg27_39

AMP-binding (20..419): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLTDGGISK
Nearest Stachelhaus code(s):: Leu or Trp DVLTDGGISK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1033..1294): X

nrpys: (unknown)

SVM prediction details:

NOTE: uncertain match

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAMFSG---K
Nearest Stachelhaus code(s):: Leu or Trp DAMFSGAIFK (56% 8Å match)
Stachelhaus code match:: 70% (weak)

gnlProkkaAJGMHPLF_52 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 15,425 nt. (total: 15,425 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

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resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAJGMHPLF_62 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 13,921 nt. (total: 13,921 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg62_10

ctg62_9

Leader:

MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG

Core:

TIVCC

Core with dehydrations:

DhbIVCysCys

ctg62_13

Leader:

MRFAKLKLRTLYQVEFANSKKYKFQEEMNMVGT

Core:

MSEKKFICLWIYNGK

Core with dehydrations:

MDhaEKKFICysLWIYNGK

antiSMASH-DB 4.0 matches for ctg62_13

100.0% NZ_JADPGO010000016.1and 1 other:

NZ_JAQDGJ010000020.1 Lanthipeptides: allorf_03808_03954_lanthipeptide

Lanthipeptides: allorf_03938_04084_lanthipeptide

1

MSEKKFICLWIYNGK

15

MSEKKFICLWIYNGK

1

MSEKKFICLWIYNGK

15

7.5% NZ_CP093302.1: Lanthipeptides: allorf_0563784_0563987_lanthipeptide

7

ICLWIY

12

ICLW++

47

ICLWVF

52

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg62_9 - Class II: Cleavage pHMM score: -5.90; RODEO score: 0; Monoisotopic mass: 519.2 Da; Molecular weight: 519.7 Da; Number of bridges: 1
ctg62_13 - Class II: Cleavage pHMM score: -3.70; RODEO score: 0; Monoisotopic mass: 1840.9 Da; Molecular weight: 1842.2 Da; Number of bridges: 1