LOCUS       c00002_gnlPro..        16370 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPGIDCLK_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:11:41
            Original ID  :: gnl|Prokka|KPGIDCLK_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16370
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16370
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3411:6370]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3412..6370
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16370
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16370
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..1630
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="YKFCLIDVEGNETIRFKIDKSKLVPGVSRIALFNSNGEVLSDRLI
                     FTYPQEQLSVQVQADKETYDPYELVNLEFTLTGKEKIPVQTPFALSVRDGMNEVESGHN
                     MLTDLLLMSEIKGYVNNPQYYFESRDDTHRKAIDLLLRVQGWRRYSWKQMTGIESLDLK
                     YGPEQGIETRGQVVSFVRQLPKPNVEVSCFLKKRGENEENSSFIEAITTDSLGHFSLIS
                     DIYGKWDLILAVTVNRKKKDYRILLDRLFSPAPRKYHYADMQVSIANAEKEKELMPEVE
                     TTPLPEEDIETFFAAYADSLAKAGNHEKNYRLKEVTIKAKKRTKEKEIYESRSKSIAYY
                     DVHSELDDIKDSGKFIGDDIHELMMNMNKNFSPVSGRNYLYYKSKMPLFVINYERTRHT
                     EMDYNKYKYIRLEAIKSIYITENLSTICQYADPRLTPFDVSDLYSCAVLIETYPEGKIP
                     TEAGKGVRKTWLDGYSQVKEFYHPNYSVLPPVPDYRRTLYWNPSVTPDKEGKAHIRFYN
                     NSRCRKLKISAETITTNGLIGTYGN"
     CDS             complement(1811..2278)
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MAKELNFTLEGVQGDLKLKYGPFNQRLYQDGREIKKQGRFNPKYY
                     VINTNGEKEEIKVVYGFDFVHVAVFRGQKIDLEERLSIREYIVGGLPVLLVFLGGLIGA
                     LFGIMGATFNYNHMRQEKSFIKQLLVSLGVSILCYVAYFIFAIGVQLIVAR"
     CDS             3412..5640
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="Gly_radical (E-value: 6.4e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5645..6370
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.9;
                     E-value: 1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_4"
                     /sec_met_domain="Radical_SAM (E-value: 9e-30, bitscore:
                     97.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEKGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYETMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(6602..7861)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGRWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(7916..8464)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8652..9404
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDTNNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(9509..10507)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_8"
                     /sec_met_domain="LysR_substrate (E-value: 1e-45, bitscore:
                     149.2, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-17, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLVVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             10577..11050
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(11154..12152)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 5.4e-69,
                     bitscore: 226.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALSAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGSSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFENSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(12207..13475)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_11"
                     /sec_met_domain="MFS_1 (E-value: 1.1e-10, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(13725..14582)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYN
                     SANKTKCKLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKG
                     VTGMDEQAVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYG
                     AHLAIDGEINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIK
                     VRKEGETEWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINL
                     YVKQ"
     CDS             complement(14567..14737)
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVWWIV"
     CDS             complement(14760..15896)
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 atacaaattc tgcctgatcg atgtcgaagg taatgaaacg attcgcttca aaatagataa
       61 aagtaaatta gtacccggag tttcccgaat cgcgttattc aacagtaacg gagaggtcct
      121 atcggatcgt ttgatattta cctatcccca agagcaatta tccgttcagg tacaggcaga
      181 caaagagaca tacgaccctt acgaattggt aaaccttgaa ttcaccctga ccggaaaaga
      241 aaagattccg gtacaaaccc catttgccct atctgtgaga gacggcatga atgaagtaga
      301 atcagggcac aatatgttga ccgatctttt attaatgtcc gaaataaaag gatatgtcaa
      361 caatccccaa tattatttcg aatcccggga cgatacacac cgcaaggcaa tcgatctctt
      421 attaagagtg cagggatggc gccgctactc ttggaaacaa atgacaggaa ttgagtctct
      481 tgaccttaaa tacggaccgg agcaaggtat cgaaacgcga gggcaggttg tctctttcgt
      541 ccggcaactt cccaagccta acgtagaagt gtcctgcttc ctgaagaaac gcggggagaa
      601 tgaggaaaac agcagtttca tcgaagccat cactacagat agtttaggac acttctcact
      661 aatatccgat atatatggaa aatgggactt gatattggca gttacagtca atagaaaaaa
      721 gaaagattac cgtattttat tggataggct attcagtcct gccccccgaa aatatcatta
      781 tgcggatatg caggtaagca ttgccaatgc agaaaaagag aaagaactta tgcccgaagt
      841 ggaaaccact cccctacctg aagaggatat cgaaaccttc tttgccgctt acgcagattc
      901 gctggcaaag gcaggtaacc atgaaaagaa ctaccgttta aaagaggtaa ccatcaaggc
      961 caaaaagaga accaaagaaa aagagatata tgaaagccgt tcgaaatcga ttgcttatta
     1021 tgatgtacat tccgaactag acgacataaa agacagtgga aaatttattg gtgacgacat
     1081 acacgaactt atgatgaaca tgaataaaaa tttcagtcct gtttcaggac gaaattacct
     1141 gtattataaa agtaaaatgc cgcttttcgt aatcaactat gaacgcaccc ggcatacaga
     1201 aatggattat aataagtaca aatatataag actcgaagcc attaaatcga tttatatcac
     1261 tgaaaatcta tctacgattt gccagtatgc agatccgcga ttgactccgt tcgatgtatc
     1321 cgacttatac agttgtgccg tactgatcga aacatatccg gaaggtaaga taccgacaga
     1381 agcagggaaa ggtgtccgaa aaacatggct tgacggttac agccaagtta aagaattcta
     1441 tcaccccaat tattctgtgc tccctcctgt ccccgactat cgtcgtacat tatactggaa
     1501 tccgtctgtc actccggata aggagggaaa agcacatatc cggttctata ataacagtag
     1561 atgccggaaa ctgaaaataa gtgcagaaac tatcacaacg aatggattaa tcggtaccta
     1621 cgggaattga taaaaaacgg gaatctcccg aaagaataca gagaaaatac agttttcatt
     1681 tttcctttcg cctgttttac ttttcccaat atggatagtt gccatcatcc atggggagga
     1741 cattcagaag tttactaaaa aaggtggcat acggaataac cgcgaagcca cctttctttt
     1801 actttccagc ctatctagcc actatcaact ggacaccaat agcaaatata aaataagcta
     1861 catagcagag tatggaaacg cccagggaaa caagcagttg ttttataaaa gatttttcct
     1921 gccgcatatg attataattg aacgtagcac ccatgatgcc gaacaaggct ccaatcaacc
     1981 cacctagaaa gacaagtaac acaggcagac cacccactat gtattcgcgg atagatagcc
     2041 gttcctccag atcgattttc tgtccgcgga acacagcgac atggacaaaa tcaaaaccat
     2101 agacaacctt tatttcttct ttttccccat tggtgttaat cacataatat ttcggattga
     2161 atcgtccttg tttcttgatc tctcttccgt cttggtataa acgttgatta aaaggaccgt
     2221 atttcaactt taaatcacct tgtacacctt ccaatgtaaa attcaactct tttgccatac
     2281 tatttatttt agaattaagt ctatttacaa agatagacaa aagctttgat tttcatcatt
     2341 cataaattat ttaatttgac gtgaatacga tataattcat caatctgtta tcttaaaaaa
     2401 ataggaatac agcaataaaa tcatttaagt tagaatattt aatcataaga tttaacaact
     2461 ttccactata gtcaccgaag ataaagttag tattcatttc atagccaaca tgctatcagc
     2521 cattaccgtt tattgtctct ttaaaaaaca accagtcatt ggtgtaaatt tcacaaatga
     2581 cggcaactga aaatctttta aataatgtcg acctcaggtc aattactgat atatagaaaa
     2641 aagtaaaaaa gaatgtagta taatgaatta gaggatagca aaacactgaa ataaaggaat
     2701 agcccgacta tatatcttac aaaaggaata caaaaaatag aaccttgctt tgattgataa
     2761 actttgataa tgtgtgtcgc tccttaaaaa gtaacgttca agccaacggt ctatataaga
     2821 ggcctcaact attgcattta caactagaca cctataatga aggcggtgtg gtaatgacat
     2881 ctgctcaagt agcggaacaa ataaaatcga ttttcccact attctacata caaggtaggt
     2941 cctcaagggt tatcattgat ctacgttgct cctcgttctt tattatgcag actgatatgt
     3001 tatatactaa aaaaagaaag tccttgaatt attgaaattc aaggacttat aaccttattt
     3061 ttttgttttc agcggagaga cagggattcg aaccccgggt acctcgcagt acaacggttt
     3121 tcaagaccgc cgcaatcgac cactctgcca cctctccaga actacggtta agtagtgctt
     3181 ttctcttaaa gcgctgcaaa ggtacgaatc attttttaac ttgcaaatta ttccgcaaaa
     3241 aaatattaga aaagtatatt tggaagtaat aaccgccctc tggcttctcc ccataaatag
     3301 gtatttttat gctattcaac ataaaatagg acccttttat atacctaaac cgaaaaaagg
     3361 ttgtaaattt gcgcgctcta aaggataact aaccactaac tgattaattt tatggaactg
     3421 aataagacct ttaaagatgg actttggagc aaagaaatca atgtaaggga tttcgttagt
     3481 aacaacatca ctccttatga aggggatgct tctttcctgc aaggacctac cgaacgcacc
     3541 aaagctgtct ggaatcactg tctcaaagct ctcgaagaag agagaaacaa taatggtatt
     3601 cgtgcactcg actacacaac tgtatctact ataacctctc accctgccgg ctacatcgat
     3661 aaagagaacg aactgatcgt cggactacag accgatcagg tattaaaacg tgccatcaaa
     3721 ccgtttggcg gaatcaatgt ggttatgaaa gcttgccgtg aaaacggagt ggaagtagat
     3781 gacagagtta aggatatctt cactcactat cgcaagactc ataatgatgg ggtattcgat
     3841 gtgtataccg aagaaattcg ttcgttccgt tcattgggat tccttaccgg acttcccgac
     3901 aactatgcac gcggacgtat catcggtgat tatcgccgcc tggctctcta tggtcttgac
     3961 cgtctgatag aagctaaaaa agaagatctg cataatctga caggtcctat gactgaagcc
     4021 cgcattcgtc ttcgtgaaga agtagccgag caaatcaagg ccctgaaaga gattaaagta
     4081 ttgggcgaat attatggttt ggatctgagc cgaccggcat ataccgcaca ggaagctgta
     4141 caatgggtgt atatggctta tctggctgcc gtaaaagagc aggatggtgc tgccatgtca
     4201 ctgggtaatg tatcttcatt cctcgacatc tatcttgaat atgaattaag ccagggtacg
     4261 ataaccgaaa cattcgctca ggaactgatc gaccaattcg ttatcaaact ccgtatggta
     4321 cgccacttgc gtatgcagtc gtacaacgat atttttgcgg gtgatcccac atgggtgacc
     4381 gaatctatcg gtggacgttt caatgatgga cgtaccaaag ttactaaaac ttctttccgc
     4441 ttcttgcaga cactttataa cttaggcccg tcaccggaac ctaacatgac tgtactatgg
     4501 agccctgagt tacccgaagg tttcaaagca ttctgtgcac aagtatctat cgacacttct
     4561 tccgtacaat acgaaaacga cgacctgatg cgtgaagtcc gtcaatcgga tgactacgga
     4621 atcgcttgtt gtgtttcata tcaggaaatc ggaaagcaga ttcagttctt cggcgcacgt
     4681 gccaaccttg ccaaagctct gctactggct atcaacggag gacgttgcga aaatacaggt
     4741 acagttatgg taaaagacat ccctgtattg accggtgaaa cactgaagtt cgaagaagta
     4801 atggccaact ataagaaagt attgatacaa attgcacgtg tatacaacga agcaatgaat
     4861 atcatacatt acatgcacga taagtattac tacgaaaagg cgcagatggc tttcgtggat
     4921 actgatcccc gcattaacct cgcttatggt gtagccggac tttcaatcgc catcgattca
     4981 ctgtccgcca tcaaatatgc acatgtgaaa gcccgtcgca acgacatcgg actgacggag
     5041 ggattcgata tcgaaggtgc tttcccttgt ttcggtaatg acgatgaccg tgtagaccac
     5101 ctgggtgtag acctggtata tttctttagc gaagaattaa agaaactccc cgtatataag
     5161 aatgcccgtc ctaccctctc gctgctgact atcacttcga acgtaatgta tggcaagaag
     5221 accggtgcca ctcctgacgg acgcgccaaa ggcattgcct ttgctcccgg tgccaacccc
     5281 atgcacggac gtgataaaaa tggtgcaatc gcctcactga gttctgtagc caagttgcgt
     5341 tatcgcgact cacaggatgg tatcagcaat acattctcga tcgttcccaa atcattggga
     5401 gcaacacaag aggaccgtat cgacaatctg gtgaccatga tggacggata ttttacaaaa
     5461 ggcgcacacc acctgaacgt aaacgtgctg aaccgggaaa tgttgcagga tgcgatggaa
     5521 catcccgaaa agtatccgca actgactatc cgtgtctcag gatatgccgt taatttcgtg
     5581 aaattgagcc gcgaacatca gttggaagta atcagccgca gttttcacga aagaatgtaa
     5641 ttgaatgata aacgtacact catacgagtc aatgggaaca ttcgacgggc cgggtctccg
     5701 gctcgtcgtt ttccttcaag ggtgtaactt ccgttgcctc tattgtgcca atccggacac
     5761 aattgaagcc aaaggaggga cagcaaccga ccctgaggaa atagttcgca tggccgtcag
     5821 tcagaaagct ttcttcggta aaaagggagg tatcaccttt tccggcggag agcctacttt
     5881 tcaagctaaa tcgcttatcc cactttttaa aagactaaag gaaaaaggaa tccatatttg
     5941 ccttgatacc aatggcgggc tatggaacaa tgatgtagag gaactattgg aattgactga
     6001 tctggtttta ttagatatca aagaatttaa tccggaacat catcagtctt taaccggaag
     6061 aagcaacgaa cagaccctga aaaccgcagc ctggcttgaa accaatcata aaccattctg
     6121 gttgcgatac gtattagtgc ccggctacag tgacttcgaa gacgatatcc ggcagctggg
     6181 agagcatctt ggaacgtacc agatgattca gcgtgtagaa atattgcctt accacacctt
     6241 gggtgttcac aaatatgaaa caatgaacaa agaatatatg ctgaaaggag tgaaagagaa
     6301 tactccagag cagatagaaa aggctgagaa actattcagg caatatttcc agaccgtaca
     6361 agtaaattga cttatataag tgtcgaaatt cgtattcacc acagattaca cgaatttaca
     6421 caaataaaga tcattggcaa tcaatagatt aagttcattc tgcggtgaat tatgacgact
     6481 gcacttattt ataattttgt aagtcacgat ataaaagtct ccctgttctt gccttaattc
     6541 attacaatac aaggcaagaa cagggagata atgtaaccgg catatttttt gccatcctac
     6601 tttaataagt gaatcgcaat cctgcctgca agttaaagtt acaaggcctt tcttttcgga
     6661 tggtttgtac tttggagcca tcatcaaaga aatacgaaac tcccggttcc acatataggc
     6721 cgacatgatc tgtcgcattg aattgcgctc ccacggcacc ggctacagaa aattgcaaag
     6781 gcttcacatt caccttatca tccgccaact ttccataaac acacttttca accattcctc
     6841 cggcagatac atagagtgta aaatatttct tttccagaaa attccagttt ccacgtacag
     6901 gaatacctat ataatgcaat ttctgactct gcatcttggt atccccctgc cgtttgatgt
     6961 cagaagacaa caacgtataa gtcaatcccg tctctacaga gaaacctttg ggaagagact
     7021 tacgtacaga cagtccgaag ctaaccggct gatgatgttc ataatccacc acggcagttg
     7081 tattggactt caggtaaggg accccttctt caaatataac ttcctgatcg gcaggaatac
     7141 tcacagctcc attcatgatc gtcatcaagt cgaccctgtt agtcatcgga cggggcgcaa
     7201 aattttcgga accatttgtc ggaagtccac ctccattacc gatacccact cccatcgacc
     7261 atctaccacc acgtttagca gaagagtctc cgataggcaa ctgatacttg tctttaccgg
     7321 acggtcgccg cgcttctttc ctctttggag gctgcgctgt cgcactttct tttttctcga
     7381 ttgcagcagt tgcttcctgt tgcggctcag ctctcttttc ctccgtcact gcctccggtc
     7441 gcttctctgc cagggaggat acctccggaa caatcaccgg atcagtattc tttgccaaat
     7501 agcccgaaac agggttgata ctcgtcgttc ctaccggctt aacgggttcg gatacagcta
     7561 cctgtacatc cggcaaggca ggttccggca atacatccgg gttgacagcc agtgaaggag
     7621 ccgttgcata acggatttca tcagctaccg gactattcag aaaatacaaa ctgacagcag
     7681 tcgttagcac caataccaca gctgccgcag caaccgccca ccggcgatac ggatatattc
     7741 gtttttcggt tacaggcatc agttcccttt ccagtcgttc ccaaccggaa gcaggcatcg
     7801 gctccgaata atcttctagc ttatccttga atgctttaat ccatttttcg tcttctttca
     7861 tcattctatt tcatttttga aatccaaggt tcacctcagt atctgtaaat acatgtcaac
     7921 cattggtcac caaccattct ttcactttct ttgccaatac actttttgcg cgaaaaagct
     7981 gtgaggcaga agatttttca ttaatcccca acatctgtgc gatttccttg tgcgacttat
     8041 cttcaaaggt gtataaattg aatacggtac gatatccggc ggggagttca ttaataaatt
     8101 gcatcagcac tttctgtggt attgcttcaa cagccgaagc atccggttct tcatacgttt
     8161 cgggaacttc atccagtgcc gtggtctggt tcatcacgtc gttctttctt aagaactgta
     8221 aagccgtatt caccattaca cgctccatcc atgctctcag agagccttca ccccgccagg
     8281 taaacttgtc gaaggagtcg aaaatcttca ggaaaccgtc gtgtaccaag tcttgtgcca
     8341 tgtccctgtc tccggcataa cgaagacaga caccaagcat gcgccctgcg tactgctcat
     8401 aaagttcttt gcgggcacga ttatctccct gcctgcaacg ttccgacagc tctaattcat
     8461 tcattctcct aaacacgtgt ttaccttata aatgcagcaa agatagaaat actgcacaga
     8521 gagaacaact cttttatcac ttttgtttct ttaacatttt aggatgcaat atttcatcac
     8581 ttcctgcatt ttctcaatac aataaagaat aaatctcaat ggataaatag gataaaacca
     8641 acaagaaact tatgaagaaa tttaatttaa taacttttgc cgtcatcctg atgttattgc
     8701 ccattttaca gtcatgtctg gacgatacca acaacgacga gtgggtcact tgtcctccgg
     8761 gtggaatatt agccatcggc acaatgaaga ttcccaatgc ggacactcca agggactttt
     8821 tcattgcgtt ggacaatgga gacaatgtac ttccggcaga tacggccgat atacgcaaca
     8881 ggaaatacac tgttgcagaa ggtcaaagag tcttcgttgg ctatctgcag atgggaaaag
     8941 agaagcccgg atatgagaac ggtaaaatat tcacgataga agatatattg acgaaagaga
     9001 tcatcccact gacggaagct acagcagaca gcattggaga cgaccgtatc aacgtcacag
     9061 cgcatgcact tacgaaagat tatctgacca tcgaatatca atatctgggc agcatgaatg
     9121 aaaataaaaa acacatgctg aacttggtac aaaacgaaat aacaggtccc ataaaagatg
     9181 acggatatat ctatctggag ttccggcata atgcctttaa tgactccccc aatcaattgg
     9241 gttcgagcct tgtttctttc aagctggata gtatagccga gcaattggcg acagccaaag
     9301 gaataaaact ccgtgtgaac accatttatg acaatataca gtatgtcaca atagatatca
     9361 acgaagacaa aaatttaaaa ataaaatcat ttcattctca ataaaacaac aagaaacacc
     9421 tacacaatca ggcaaaacga gtaataattc tgatacataa aagaaataag gcggcgatgt
     9481 ttgtgaaaat atcgccgtcg tttttatatt ataccagaca ctgaacggcc tgcagggtaa
     9541 gcatctcctt gggaaccgcc gcctgaatct cctctttcaa aacctgcagc agactggtgc
     9601 ggatgaagtc tttccgggtc accaggacaa tctgacgggt aggccgcggg atagcaaacg
     9661 gacggaccag ttctttctgc tcttcgctca attgcatcac tgccagttcg ggaataaacg
     9721 taatcccctt accactctcc accatatgca taaaggtttc catactaccc agccgatacg
     9781 ccatttggct gatcttaacc gcttccatct gacaaaaacg aaccaactga tcgcggaagc
     9841 aatgcccttc gtcaagaagc caaagccgtt cccctgtcac atcggacgta cgaatcacat
     9901 cgtgcttgaa caacggttcc ttctttgaga catagcccag gaattgctcg tagaataagg
     9961 tctcttccgt taatgcggca tcatccagca tgctggcaat gatagcagca tccgcttcac
    10021 cggtcagcag agccttgcga atgtcgggcg tcttcatctc catcacccgt atatcaagat
    10081 ccgggtattt ctccatcagt tgcggaaaga aacggggcag aagataaggt gcaatcgtcg
    10141 gtaacactac caatcggaat gtacccgaca gggagtgctg ttcttcgctg atgatctcct
    10201 tgacacagat aacttccgaa agaatcttac gggcctgttc cagcactttc ttaccaatgg
    10261 cagtagggca aaccggtgtc atgctacggt cgaacagttt cacccccaat tcgtcttcca
    10321 gcttttggat cattgcactc aaagtaggtt gcgtcacccg gcaatactcg gcagctttag
    10381 caaaatgccg gaactggtcg acagccagaa tatattccaa ttgttgtata gtcatcgttc
    10441 tctgatttat taaagatata gaatctatca atgcaaagat agaaattttc agtttgacac
    10501 gaatcatttt gtgccgtatc tttgttccag ataaaaagaa gaaatatagt attaactcaa
    10561 aaaaaacaat atcattatga agactttaaa ttatacacat ttggaagaaa aaggagctaa
    10621 caccatcgta ctgtcattac agcaactgct tgccgatttt cagattcatt atgcaaacct
    10681 gagaggattt cactggaaca tcaaaggaca cggtttcttc gtactgcaca gcaagtttga
    10741 agatttatat aacggagccg ccgaaaaggt ggacgaaata gccgaacgta tactgatgct
    10801 gggaggaact cccgccaata aatacagtga ctatctgaag atggcgcaga tcaaggaagt
    10861 ggacggagtg aataaggccg acgacgctct gaatcatatt ctcgaaactt acgggcatct
    10921 gattgcggaa gaacgtaaaa tcctgtctct cgcctcttca cacaacgacg aagtaacagt
    10981 ggccatgatg agcgactacc tgaaagaaca ggaaaagatg gtttggatgc tgactgcata
    11041 caacggataa cagccgaaag ggtgtagcca tctgaccgaa aaggtgtagc catacaaaca
    11101 aaagggtgta gccatcccgg cgggatagct acacccttcc tgttttattc gattcagatg
    11161 atacttgtac gtttggtaaa ttcaataatc tccggaatgt atccgaatgc gagcccggtc
    11221 actgtatccg cacacccata atagatggca atccgtccgg tctccgaatc atgaagcgcc
    11281 gcgcatggga aacagacatt aggcacatca cccatacatt cgtaatcctt ctgaggtgaa
    11341 atcagataag gccccgaacg gaattttact ttccagggct gatcgatgtc aagcagtgcc
    11401 gaaccaaaac tatacacaaa accgttgcag gaagccaata caccatgata gatcagtaac
    11461 cagccttccg aggtttcaat cgggataggc cctgcaccga tcttggtaca ctgccaggca
    11521 ctgttttcga acggagccgg cgacataaca tgacgatgac gtccccaaaa ctccatatcg
    11581 ggagactcgc tatagaaaat atctccaaaa ggagtatgcc cattatcact cgggcgactc
    11641 aacatcgcaa aacgaccgtt tatcttacga gggaacaaga ctccattccg attgaaggga
    11701 ataaaggcat tctccaactg gtgaaaagta acaaaatcat aggtgtaggc cacaccgata
    11761 gtaggaccat gatagccatt acaccaggtc acatagtagc ggtcttcgat aaagcaaacc
    11821 cgtggatcat atccatagac ccaggttcca acctcagcgt catcacattg aaactttaac
    11881 ggttcttcgt tgatatccca atgaacagca tccttgctgg atcccacatg caaacgcatg
    11941 cgacgattag tatcatcaca acggaacacc cctgcatagc catccttaaa cggaactacg
    12001 gcactgttga atatactgtt tgaagtaggg agcaagtcgc gcggaataat cggattggcc
    12061 gaacaacgcc acactacatc tttacatcct gccggacgtt cttcccaagg catagccgac
    12121 aaagcagcac ctgcaatttt aatttcttcc atgattcgat taaattaata ttatgtatat
    12181 atcttgttta tattgaaaat ctctttttat ttcttctttc cgtccggata tgtgaaaggt
    12241 accagccaag tcacgataaa agccggtatg gtagcgataa gtacccagat aaagaaatcg
    12301 cgataaccca gccaatcgct caggtatccg ctcatcattc cgggaagcat cacccccaga
    12361 ttcataatac cggtagcaaa agcataatgt gccatctgat gtttgccggg agccacttgc
    12421 tgcatcataa agagcatcaa tccgacaaaa ccaaacccgt aacccaagta ttcagacaca
    12481 atggccatac caataatcca tagatcggaa ggctggtaaa gggctaacag gaaatatacc
    12541 aagaacggaa tattaaaagc gcaacataaa gaaaacaaag tcttccgaag tccgaaagcc
    12601 gaaatgtaat aaccggccaa aagcgaaccg agaataaaag ctcccgctcc gaacgtacca
    12661 tataccagtc cgatatcctg agtgctgagt cccaatccac catccgcaac cgacgctttc
    12721 aggaacaacg gtacaatctt gatggcatat ccttcggcaa accggtacaa aatgataaag
    12781 acaatgtaga aagcaatatg ttttttttgg aaaaaagagc ggatgacttc ccaaagcata
    12841 ttcaatgcgt cactcatcgt attcacttca ccggaagcgc ctcctcccga aggcaaaatc
    12901 cggatgtggt aaagaccgat cagaatcata atacccgcac acatcaacat gacaatcatc
    12961 caggcatgta ccactccaaa ttcatccttc agcatacctg ccaaccaaac caagcctccg
    13021 ttggcaagta tcttggccag attataaaaa gctccctgcc aaccgatata cttggcttgc
    13081 tgggtagcag tcagttcagt caggtatact ccgtcccccg caatgtcatg agtcgcacca
    13141 ctgagagcaa tgatccccat cagagcgatg gcataacgaa aaaagtcggg cagcggcagc
    13201 gaaagtgcta ccaatgcaaa tgccagtccg gtaatgattt ccgtagcgac aacaaagtac
    13261 tttttcgttt taaacatttc cagaaacgga ctccataaag gcttcaatgt ccagggaagc
    13321 ataatgagag aagtccagaa agcaatctgt gcattcgaca cttccatatc ggaaaacata
    13381 aggacagaaa ccatcgaaag ggccacaaac ggcaatccca tagcaaagta aacagtaggc
    13441 acccaacata cagggcttat cggcttttta ttcatcagtt agttttttat aataattcca
    13501 tcggttaaca attccagtaa gcaaagatag gggatattaa aaacataacc caagattacg
    13561 acaagaagtt gctttcatta tttaataata caactcaccc gggaaaacta ctaacctcta
    13621 tcaccctttt tttattaaac tttatcaata cgacacacgc aaagaagcac cgaagacttt
    13681 catccccgat gcctctcgcc cccttatcta caatctaaac acctctattg cttcacatat
    13741 aaatttatct cagcaaaccc ggtataatta tccggagtca gacagtttat tctgaattcc
    13801 tttacattcg ggataggtgg ttcgatggcc gcatattgcg gatcagcccc tttaaaattt
    13861 ctgaaagtca agactctcgg gtaagtaacc cactcggttt caccctcttt ccgaacctta
    13921 atctcagcac ttctcagatt ataacccgat ccgtaggcac tctgtttagt gaccgaaaat
    13981 ccggttaagg taacaggccg gtccagtagc gtattccacc aacactctcc ggcattagcc
    14041 actccccatg taaaccaagt agtatttatc tcaccgtcaa tagccagatg tgcaccatat
    14101 ttggcatcat catcggcata aacattgctg caacttacac tccacgcact tcgatctaca
    14161 gcggaccaat tcccgggttt cgtataactg gtataaagca cgctggtata aatccggata
    14221 taaaccgtct tcatagatgt actgacagcc tgttcgtcca tgcccgtaac tcctttaagc
    14281 gccacgggaa gcacatatcc gtcaggatta gtcaactttt ctatattctt caaaacgacc
    14341 tgaaaagatg aatcggccac tgtctgtccc gtttttaaga caacttcact tgtttcaatg
    14401 gtataattat cttggggcaa caacttacat ttcgtcttat tggcagaatt gtaagtatcc
    14461 actttcagcg tatctactcc caaagcggca gtgacatccc gcgtaaccgg ctgtacggca
    14521 cacaattgta tttcaaaatc agaacggtcg gcagtagagg aattgctcac acaatccacc
    14581 ataccgcagc acccatttcg gcccccggtg caactcccgt tctgatatat atcttttgat
    14641 atttgtccat ttcatcatca tcgttgctgc acgaagccaa cgatacaaag cctgttatca
    14701 ggcagattaa ggtcacaaaa ttcaaatgtc tattcatatc ttatcttctt tttacatagt
    14761 tattgcttat caaaacgaac atgctctttc cagacaagag ttcctcctgc caccaaatcg
    14821 tatccgtgtc cggtacagtc gacaaaggca tttcccttac cttcatccat tttccaatag
    14881 cctatcaggt tcggatcggc gggcttcacg gcaaaataca tgttggactg aatttgcgtc
    14941 tggctgattg cgctcttcca aagacgcacc tgggccatct gacaattgtt gcggaagtaa
    15001 ctaccgctcg aaaccatgtt catcttgtcg aatctaaccg ggccaccctt tgtctgcaga
    15061 gtcacgtcga gcactccgtt gatataaatc gacaataacc cggaagaatt ataaacgaag
    15121 gccagatgat accacttatt cttctcaaac aaagtcaccg tattgacctg acttccaagt
    15181 gtcttcacct gtaatgaatt ataagggatc atagcgtcac cgaaacggat ataaacctcg
    15241 tggtcgctgc tgcccgaatt aaatatagcc tgattattaa tatcgaatcc gtccatctgt
    15301 acccaagcct cgagtgacca ttcattggtt gtcactcccc acaattcgtc cttggcgggc
    15361 ttcacggcat tggtcgtatt cataaacggt acagactgta tcagcggctt atccagcaaa
    15421 atgataaact tcgacgaaag cccgattgtg gacaccggcc cctgaatttc tgtgagagat
    15481 accggaatag catacaattc tccgttttcg tttgaataag gtttcactct aaactcactg
    15541 gggattgcgc taacatcgcc tgccgctatc tttatctctt tgtcataagt aaaatactgc
    15601 tcgggaagga cttcgtacga agtttcatta gcttcattgt actctttaag aatagaagga
    15661 tctaccgtca ggacagcagt cacattttcg gttacaggct gtcccacacg tacggtcaga
    15721 gtagttgttg ttacattttc aggatcaacg gtaacctttg ccgaaccatt ctcggatgct
    15781 tcattcaaat aaatcgcatt gtcgataacc tggtaatcgg catcgttgca tcctgccagg
    15841 atcatcggca gaacgaaaca ggcaagcaaa tattgtttta ttgttattct tttcataatc
    15901 aaattcttta aagtcatttt acagcaggat tcattattct gattgcttca cgcaggtact
    15961 tatattcgat gtcgcccgga tagtcatatt ccatgtgata ggtgcctact ccacccttcc
    16021 gtacctgttt tccgtcaata gtcggagtcc agcgtgccat gccggcaagt gctctcattt
    16081 tgtttccgta acgatctaca taatcacctc ctcctgtcgg agcataagat tcgaaattct
    16141 ccgtaacgat gtacatatta gccactttct ccggaggaag tattccttta aagttggcaa
    16201 tcgtaccagc cagacgtctg tcaagattag cgtcggaatt acccgcaagg ttagagtatg
    16261 cctgcacaat gaaatagtca aagtaaggcc cggtttccgg atgaatactt tgaggctcgc
    16321 catcaatcac aagtagccgt cccgtacccg atttaggtcc gattctttct
//
