LOCUS       gnlProkkaIPNHIOEK_77   12336 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPNHIOEK_77.
ACCESSION   gnlProkkaIPNHIOEK_77
VERSION     gnlProkkaIPNHIOEK_77
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 09:01:25
            Original ID  :: gnl|Prokka|IPNHIOEK_77
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12336
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12336
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1982:2336]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1983..2336
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12336
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12336
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             29..418
                     /locus_tag="ctg77_1"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTSAEAPAPAAEAPAAE"
     CDS             572..1963
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102.4; E-value: 3.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg77_2"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGTDATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFTVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLVVALLLKKADRKYGYKLEE
                     PNIQK"
     CDS             1983..2336
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_3"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-10, bitscore:
                     30.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4e-17, bitscore: 52.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGKEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(2344..3393)
                     /locus_tag="ctg77_4"
                     /transl_table=11
                     /translation="MKKNILILSALFLSTTAIAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQTTKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGIPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSDKPAAKMPVAKATESNIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNAILRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSKKLGVVANNDLAGEPYYISVTDLKNPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLVYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(3464..4591)
                     /locus_tag="ctg77_5"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLVGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSATLPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLSFNRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQVTPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDNPIPHASLEAVNIEEDSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGRLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLTKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVRSVNNL"
     CDS             complement(4685..7513)
                     /locus_tag="ctg77_6"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHTWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASRESVVLLKNAGE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGC
                     DLVDAHWPESEIIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVHLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDTDMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTVWQGNKGDYITFALKNGTQV
                     DKVTIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVGIAEVKF"
     CDS             8938..9423
                     /locus_tag="ctg77_7"
                     /transl_table=11
                     /translation="MKIHEGKCTEKILKERERIGSRLAILRKKRNMTQEELANLCGVNR
                     VNIAKIEKGAYNVSIDILSKVTSALGFVIDIKVDSSVCPTHFSQRKPVKLVIGEDYYVS
                     FGNNEAHRCKLVDIPEMYQGQRIKIETPTPRGSITHILFADEIGTTPDEAVMNQVTM"
     CDS             complement(9623..10420)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 57.2; E-value:
                     2.9e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg77_8"
                     /transl_table=11
                     /translation="MQKRHTDRESYFDEQSQTSKNYYIPYIKEVIGHIPDKVLEVGCGE
                     GGNLLPFAEAGCRVMGVDIDATRIEQARTFFAQRHQQGQFIATDIFQLKDKATNFPLIL
                     LHDVIEHIRDKERFFSGLQEHLSADGAVFVGFPAWQMPFGGHQQIAHSHIVSHFPFLHL
                     LPRTLYRWILRLCGEQERVIMELLDIKSTGCTIELFNRIARQANYQIIDRRLYLINPHY
                     KIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             complement(10502..12142)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 69.4;
                     E-value: 4.9e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg77_9"
                     /transl_table=11
                     /translation="MDTKALVTLCQKGNGQALSLLYENYSEKMLKVCLRYIPDPTIAQD
                     LLHDGFVIIFTSIHSLRNPEKLEYWMKKIMRNLALQYLNHANANPTIPLTDIPEEEEPA
                     ENPFCPDFISYDKMLDIVESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFR
                     AKILLKKMLAGYRVFIVLTVLLLFPTLYDYLYREKKSIRENRLSKVSSRQAGSTQQTKK
                     TDTPRTDEQCYTKENLNKRERIIPPVPVSTEWPLAIPTMKDSIHKYPIPSPFTGQTITN
                     RQMAFVFSPSLMPPTRKKKSGKWKLMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQV
                     STWEEYYSYLHTRYQQGTLGKDSIGLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNE
                     RWSLETGLQYTLLRSEFTTGEAFRIQDNQKLHYIGIPLRLSYCFWHYKRFSSYVTAGMQ
                     VDIPIKGTLQSFHVTDSIPHKLDSQPVSAPWQWSVNTSIGIQYRLTPQAGIYLEPTVNY
                     YIPDGSQLLTIRKEHPFIFTLPVGLRISW"
ORIGIN
        1 attattaacg ctaaatcaaa ataacaaaat gtatttatta ttagttatct taatgctgat
       61 tgcatctgtg ctgatgtgct tcattgtatt gattcaaaat tctaaaggag gcggtctggc
      121 atcaggcttt tcatcatcca accaaattat gggtgtgcgc aagactacgg attttttgga
      181 aaaagcaact tggactctgg cagctgtcat ggtagtcttc agtattgttt ctgcttacac
      241 tattccttct tccacaggta agggcggtga tgtgattctg gaacaggcgc aacaagaaga
      301 aaaaactaat ccttataaca tgcccgtagg tacagaagct ccgcaatcgg aggcccctgc
      361 agctacaact tcggctgaag ctcctgctcc tgcagcagaa gccccagcag cagaataaga
      421 taaggatatt gcggatgact cccgcttgga aaaataagag aaaggttgat actgaaaagg
      481 tgtcaacctt ttttcgtttt aatgaagtat ttatttacct ttgtcagcaa cttatgcaat
      541 ctgattaata aattgaaatt taaatagtgc aatgacagaa caactcaaac ttaaattgaa
      601 tgattccaag gctacccgtt ggggggcatt ggtgattgtt gccttcacga tgatggcagc
      661 ttattatgta aacgacgtgg tagcgccatt gaagacaatg ttggaaacgg acttggcttg
      721 gtcgagtact gatttcggat tctttaccgg tggttatagt ttcctgaatg tttttttcct
      781 gatgctgatt tggggaggat taatcctcga ccgctttgga atccgcttca ccggaaagct
      841 ggcaactatc ttgatggtag gtggtacagc acttgaatac tatgcaatga cgggacttgc
      901 cggtaccgac gcgactttat ttggaatcaa tgaaatattt ggctataaaa caggggtgtt
      961 tgttgctttt gccggttatt ccatctttgg agtaggagcg gaggtcgctg gtattacagt
     1021 ttccaaaatc atagctaagt ggtttaaggg gaaagagctt gccacggcta tgggggtaca
     1081 agttgctttg gcacgtatcg gttcgcaggc cggttatgca gtagccattc ctttggcccg
     1141 tgctttcggt atttccacac cggtgttgtt gggcttggtt ctgttgttgg gtggtatgat
     1201 tgctttcttc gtctttacag tgatggacaa gaagctggac aaacagatgg aagctgctgc
     1261 cattgctgcc ggtacggaag atgaggaaga gaagttctcc tttaaggatg tgaagaatat
     1321 tctggtcaat cccggtttct ggctgatagc attgctgtgt gtattgttct actcttgtgt
     1381 attcccattc cagaaatttg cttccgagtt gatgattatc aaatacggta tcaatgagaa
     1441 tgtagctggt acgtttgccg gacttccggc attgggggcg ctgattctga ccccggtctt
     1501 tggtggtttt attgacaagc ggggcaagtc cgcatctatc atgctgctgg gttcagccat
     1561 gctgatatgt gtacatttta tttatgctat tcccgatata aactattggt tggtagctat
     1621 tgtgctgatg ataattttgg gcatcgcttt ttcgctggta ccttctgcca tgtggccggc
     1681 tgtggccaag atattcccgg taagtcagct gggtacggca tacgcattga ttttctttat
     1741 ccagaatatc ggtctttggg gtattcctac attgataggg tgggtgcttg atgcctattg
     1801 tatatccggt aagaaaccag atggaacgaa tatgtatgac tatacggtgc ctatgtgcat
     1861 atttaccggt attgcctgct tgtcccttgt agtggcccta ctgctgaaga aggcggacag
     1921 gaagtatggt tataagctgg aagagcctaa tattcagaaa taataggaaa agcggatatc
     1981 gtatgatgga aatacccgaa ggaaaagtaa gtctgttgga cgctgttccg gtccgctgtg
     2041 gacatataac aaccgaatgg gaaggtgagt gcgccgtact cgcctaccca cggtttaaat
     2101 acgaatggat gcgtcgtttt ttattgccga aggggatgtc tcctgacatc catgtgaggc
     2161 tggaagaaca cggcacagct gtctggaatc tgatagatgg acatcgtacc gtgcgcgaaa
     2221 tcatctctct gcttgccagg cactttggga aggaagagaa ttatattccc cgggtcaccg
     2281 cctacgtaat gcagttgcgt aaggatggat ttatccagtt gacaatccgg aattagaatt
     2341 cctttattcc ctatccactt ttatcaatcc tcccgttgcc gtatcaaaca gcactttgat
     2401 ggtagaattc ttgttgaaca gtaccggtgc gaggtattct acggtgccga attgggtaat
     2461 gggaagttgg tcgtcaaaca atttcttatt gttatacacc aatgtcactt gtgccttgcc
     2521 cggaaggtta taggctacac cgtccacttt ctttttgcct tcctcggtgg cagatacatc
     2581 gggatttttg aggtctgtga cactgatgta atacggttca cctgcaaggt cattattagc
     2641 taccactcct aactttttgg agaaacggaa agccacttca tctttcatct ctttaggcgt
     2701 caaccggata gtgaatgtct tgggttcttt ctttattttg cccgagaaca tttccgtcat
     2761 ggccgtttcc tgctggttca gattgtcgag catcagcttg agctgggcgc cgtccttggg
     2821 catattgtct gcctcaccgc gcaggatggc attcttgctt tcgcggatgc tgtatatttc
     2881 cttggccacc agctcggcca tcttggcact ggagttggac atcagtattt cttctgtcag
     2941 aaaactgcgt gggtcaatgt tgctttcggt ggctttagct acgggcatct tggcagcagg
     3001 cttgtcactg aacggaatgt tgatggagcg gacaatcccg tcttcagtaa gctccataag
     3061 gggtgccacg gttttgtctt tcattttgac gaaatagaca ttgtccttat ctggtatacc
     3121 ggctatacgg gtttctatct tatccagtgt ccagaactct tccggttcgg cagacacgtt
     3181 gttgagacgc agatagcggt cggcatatct gcaaaattct ccgggagtgt aggtatgctt
     3241 ggtggtttgc aatacgattt ctatttctgt tttgggcaac atataggtta ctccatagtc
     3301 tttgccacgc atcacaccgg tggttacgtc tgtttgcgct atggcagtgg tagacaagaa
     3361 cagagctgag agtatcaata tattcttttt cataatctac attcgtttag actgatttag
     3421 ctaagggaca aagttaatga agttatcttt gctaaatatt gctttataaa ttattaacag
     3481 atctgacgaa ttgtacgcaa accggcatgt cgactacaat gtcctgatga gtgtcttcta
     3541 aaagtccggt aacttcgttt cgtttataca cctgaatgac attgctgtca cggcaggcgg
     3601 caagcaagta tttgccgttg ggtgtaatgt tgaagttgcg aggatggatg ccggttggct
     3661 gataacctac ctttgtcaag gtcccatttt cgggattaac ggcaaagatg gcgatgccgt
     3721 cttctttcag ccgattactg gcatagaggt atttcccgtc cggactgagg tggatgtctg
     3781 cacttccacg ggcggctacg gtgtcggctg taatggtttg tatctgttcc aggcggccgt
     3841 catcgtaact gaaggcgatg actttgccgg acaactcggt gatgagatag gcaaacttcc
     3901 cgttgggact gaatgtcagg tggcgcgggc cggaatcctc ctcaatgtta acggcttcca
     3961 gagaagcatg aggaataggg ttgtcggggt gcatcacaaa gcgcaggatg cggtcggcac
     4021 tgaagtcggt ggcgaagatg tactttccgt ccggtgaaaa gaccgtgcaa tggatgtggg
     4081 gagtgacttg tcgtatggcg tcgggaccgg tggcagagcc ttgaaagagc gtgtctgcag
     4141 gggccaaagt gccgtctttc tgtaaaggaa agacggacat ggttccaccg ctgtagttgg
     4201 cagtcaacac ttcccggcca ttggtggcca cgtagcaggg gtcggcgccg aaggtgggaa
     4261 cggtgttcag caggcgcagt tctcctgttt cccgattgaa ggaaagggag ctgagggctg
     4321 ctgtgctgtc gttcatttca ctgacggcat agacaaattc gccatcttcc gagggaacga
     4381 ggtaggaggg attgggcaat gtcgctgaac tgagcgggac ggctgttccc gtctcctgat
     4441 taaagcggaa ggtatagata cccttgcttg aaccattcgt gtaagtaccc accagcatgg
     4501 caagttcgtc ctggtcaccg ttagtgccct ttggagaaga gccacatgct gtcaaaccta
     4561 atccgagcat acagaaaaga agtgttttca ttaatttaat gtgctaatat gtcaatatac
     4621 taatgtgcca atgcccctgc ggcatataca gcgcagccaa ttagcatatt ggcacattag
     4681 cacattaaaa tttaacttcg gcaataccga cgcggtcatc gttcagcacg atgcggaggt
     4741 cgctggcggt agtgcctttg aacggatagg aaatcagctt gccatattcg ctgacggtgc
     4801 ccgaatatac ggtgaggaac tgtccgccac cgcccgagag ctggatttcg aaggttgccg
     4861 gtaggttgtt gtcgcgtgta aaggcgatgg taactttatc tacctgggtt ccgttcttca
     4921 aggcaaaggt aatataatct cccttatttc cttgccatac ggtattgatt ttttcgtcga
     4981 gcacgttttc ggcatcctct gggttggtgc tggcactcac acgctttgct ggtttttggg
     5041 cttcaatggc tttggcacgg gtctggtagt cttctacggt cagcgttccg ttcaggcgga
     5101 tgtcttcgga agaggcgccg gccatgagca cgaagtcgcc gggttccacc acccatttca
     5161 tgtcggtgtc cagaagctcc aggtgcttgc ggtcgatggt gaaggacagc tcctgggctt
     5221 cgcccggttc gaggtggatg cgctggaagc ctgcaagatt cttttcgtag gtggtgatgc
     5281 tgctcagtac gtcgcggata tagagctgca ctacttcatc tccggcacgt ttgccggtgt
     5341 tggtcacctt caggtggacg gtggcagact cgttcggggt gatgactcgg ggagtgatgt
     5401 cgaggtcgga gtactcgaag gtggtgtagc ttaagccgta accgaagggg tacagtgctc
     5461 cgttgatgcg tgacatgttg cccgtgggcc ccggattctt accgccgtct atctgtgaag
     5521 aaggcttgca ggggaagttg aaggggattt gccctacggt cttggggaag gtcactgtca
     5581 gctttccacc agggttgtag tcgccgaaga ggatgtcggc cagggccgtt ccgcctttgg
     5641 agccgggata ccaggcttcg aggatggcgg ggacgaactt gtctgcccag ttgatggaga
     5701 gcgggcgtcc gttgatgagt atcagtacga cgggcttgcc cgtggcttgt atggcttgaa
     5761 gcagttgcaa ctgccggccg ggcaggtcga ggctggtgcg cgatttgttt tcgccgcagg
     5821 tgcgttgtcc accgcccaat actacgacgg caacatcagc ttggcgggca ttttctacgg
     5881 ctttgtctat ctcggcttgc tcgtcgtcgg tcagaggata gtctatgatt tcactttcgg
     5941 gccagtgggc atctaccagg tcgcagcctt tggtgtagag cacctctgcc ttgccttttg
     6001 tcttttcttg aatgccttcc agtacagtgg tcacctctac ggcaaggggg ccgtaatggg
     6061 tcagcgcgta gccttcttcg ttggcattgg gaccacagac ggcaatcttc ttggtggagt
     6121 tgatgtctaa gggcaacagc tcaccggcat tcttcagcag aacgacggac tcgcgggatg
     6181 cctgcaaggc gatggcttcg ttctcttctt tttccacttc acggtcggca ccggcaaggt
     6241 ctgtctggta gggggcatcg aacagaccaa tgaggaactt tacccggagg atgtcgcgca
     6301 cacggtcgtt aatgacttct tcgctcagcc cgccttcctt caccagttcg cggaggggaa
     6361 ggacgaagga gtcgggcgag cggaaggtac agcgtacgtt cagcccggct tccacgcttt
     6421 ggcggacggc ttctttcatg tctttggcgg tgccgtgctt ggtgtagagg tattctacgg
     6481 cgtcactgtc ggatacgacg tagccacgga atcccatttc gccacgcagg cgggtggtga
     6541 gccagtagta gctgccctgc acggggatgc cgtcgtaatc gttgtacgaa ctcattacgc
     6601 ccagcatgcc agcttcccgg atgacgcgtt tgaaggggta gatgtgtatg ttttccactt
     6661 cgcgcggcga catttgcggg tccacgcgtg ccatgccttc gcgggcgcct ttgttgttac
     6721 tgtaagcggc aaagtgcttg ccggtggcgg ccacttggtg gttgtgctgc aagccgcgca
     6781 ccatttcgat gcccagttcg gctacgaggt agggagattc gccgtaaact tcttcgtagc
     6841 gtccccagcg ctggtcgcgt cctacgtcga ggatgggggc gtagacgttg gtgtagccca
     6901 gcatgcgggc ttcgcgtccg gtgatgagtc ctacttggcg aatcagttca cggttccagg
     6961 tatgtcccag tcccagttgg gtggggaagt tggtggcgcg gtagctttcc acgccgcgta
     7021 tgccttcgtt ggtaaagtct acggggatgc cgagacgggt atcttccaca aagaaccgct
     7081 gtacctcgtt cagtgcccag gtgtggcgcg aggcgggcca gacgtaggca ttgtccgagg
     7141 gaggcagccc ccattgctgg aagccgttca ggtgttcgtc gatggcgccg ataccgtctt
     7201 tccagagcag ctctttccat tcgggggtgg ggaggtcgtc tttcagtacg cgtttgtagc
     7261 cgtagagggt gaccatttgg caggtctttt cgtccagcgt catctgttgc agcaggtttt
     7321 cgatgcgtgc ttcgagcggg gcggaggggt cttcgtacac gtctttcact ccgtttttgt
     7381 tgaagtctat ccaacctttg cggtacattt cacttttcac cggcttgtag gttgccggtg
     7441 ttttggcagg cttttgtgcg cagagcagtg tgcttcctcc aagcagcagg gttagggcta
     7501 taaggttctt catgatatgt tctaaaaatc tcttggttat tattgtttct tttgttgaca
     7561 aaaatacggc taatgtgtga aataaaggga taaaatagtc cgaagtatcg gcttttattg
     7621 tccgaagggt cttcctctta ctaaaaatat cctccaagac gctaccgggg aattcaaatc
     7681 attattagac gaaacatatc attcactttt aaaaagaaag agagaacact ataataacct
     7741 gaaaagtaga tgcaatcgcg gtgtatacaa gtattacggc tacatctgtt aaacgagggt
     7801 gtatttatat aataggaatc tgttggcgga attgttgctt gtacggaaga actttctttt
     7861 caaccttggg atgtctaaac ccaaccttgg tttagacatc ccaaggttgg gtatggaaaa
     7921 accaaagttt gggatagatt gcttccttaa ttctttccgg tttttcagtt aacttcagag
     7981 actttttccg ttaacttccc atctcttttg tgcaaatatc cattacagaa gatagatatt
     8041 ccctcttgca gggggtaatt ccgtcaacgg atactggctt tggtagctgt ttgaacattg
     8101 atgacaatgg ggtgcacata ttctatgtat ggaagattat tgtttttatc acgaaaagtc
     8161 agtattagct aatatttgta aatatatggt gattgctaat aaaagaatat gtatctttgg
     8221 gccaaagaaa gcggtagagg atgaaaaata aagtagcatt tatccctttt tcaccctccc
     8281 tacttagcaa tgagttacgc aatcttttaa atttcagacc gttacaaagt catggggttg
     8341 actggatttg acagcgggca gaaatggtaa gtaagcatgc agtgcgtcgt tgatttgcac
     8401 tttaatctca gtcctcaaaa ttttatctgg cgaaactcgt tacgctctcg ctgcttaatc
     8461 gaagtatagt agattgaagc ttaatcccgg caccaggtgc tgggacgtga catcactcgg
     8521 aagctgttgc tccgaagcat tccgataaag tggtgcagtc aaatcgggga tagttcgtgt
     8581 cagcctcgtg gcgcgggtga aaatttagag gataaggcaa cggttgatgg ctttggttct
     8641 gccgctgcac gaaaatttag gcaaagataa gcatgtagaa agcttatgat ttcctcgttt
     8701 ggacgagggt tcgattccct ccagctccac ggaaatagta aaaagaagtt tgtaagtcct
     8761 tgaattccag taattcaggg gctttttctt ttcttctact ccccctactt tttatattca
     8821 tttagaaaat agttgtagta aatgtgctac aattcaaaat taatatctac ttttgtctgt
     8881 tcaaaaacca ataactatta gaagtggggg caacacttta aattctgcaa cagatttatg
     8941 aaaattcacg aaggaaaatg tacagagaag attttgaaag aacgtgaacg gattggtagt
     9001 cggttagcca ttcttcgcaa gaagagaaat atgacccaag aggaattggc taatctttgt
     9061 ggtgttaatc gtgttaatat agccaagata gagaaagggg cttataatgt gagcattgat
     9121 atactatcta aggtaacatc cgctcttggt tttgtgatag atataaaagt ggatagctct
     9181 gtttgtccga ctcatttctc tcaacgtaaa cctgtaaagc tggtaatagg ggaagattat
     9241 tatgtcagtt ttggcaataa cgaagcccat agatgtaagc tggtggatat tccggagatg
     9301 taccaaggtc aaagaattaa aatcgaaact ccgaccccga gagggtctat cacccacata
     9361 ttatttgccg atgaaatagg aacgacacct gacgaggctg taatgaacca agtaacgatg
     9421 taaaaacatt aaaagggagg aagtgcaagt tcccctttta ttgaaatcac cttcgctaca
     9481 accatctgca gcgagggtga ttttttagtt tatgagggtt tctacacacc ctctttcatc
     9541 agggctattc agaaatttaa tggtttcttc tgaatatata atcttaaatt gatggttcgg
     9601 aatcaattct aaagctggga aatcagtagt gattaacagt tttagtccct ttctttaata
     9661 tgtaaaagca acttgtacaa aagaagtttc ttatgtacgg gatagcagca ataactccgt
     9721 tgagccttcg tggggacaag ccgaatttga ttttataatg tgggtttata aggtacagtc
     9781 tccggtcaat gatttgatag ttggcttgcc gggcgatgcg attgaacagt tcgatggtgc
     9841 atccggtgct ctttatatcc agtagctcca tgattacgcg ttcctgctca ccgcatagtc
     9901 ttaatatcca tctgtataaa gtgcggggaa ggaggtggag aaaagggaaa tgtgaaacaa
     9961 tgtggctgtg tgctatctgc tggtggcctc cgaatggcat ttgccaggcg ggaaacccta
    10021 caaatacagc tccgtcggca gacaaatgtt cttgtaggcc ggagaagaac cgttctttgt
    10081 ctctgatatg ctctatcaca tcgtgtagaa gaatcagggg aaaattcgta gccttgtcct
    10141 tgagctggaa aatgtcggtg gcaatgaact gtccctgctg atgcctttgg gcgaagaagg
    10201 ttctggcttg ttctattcgc gtggcatcaa tgtctacgcc catcacccgg caaccggctt
    10261 cggcaaaggg gagcagattg cctccctctc cacagcccac ttccagcact ttatcgggga
    10321 tgtgtccgat gacttccttt atgtagggga tataatagtt cttgctggtc tgtgactgtt
    10381 catcaaagta gctttcccgg tcggtatgtc gtttctgcat gttctttgtt ccttcttgag
    10441 tttgattatc catataaata gataatcagt cgggtaaaag actgcgtggc gcatcgtttt
    10501 tttaccagga aatgcggagg cctaccggga gggtgaatat gaacgggtgt tcctttcgga
    10561 tggtgagcag ttggctgccg tcggggatat aatagtttac agtcggctcc agatagatac
    10621 ctgcctgggg tgtgaggcga tattgtatgc ctatacttgt gttgaccgac cactgccagg
    10681 gagcacttac cggctggctg tcgagcttgt gtggaatact gtctgtgaca tggaagcttt
    10741 ggagtgtccc ttttatgggg atatccacct gcatgcctgc cgtgacataa ctggagaaac
    10801 gtttgtaatg ccagaaacag taggaaagcc ggagaggaat gccgatataa tgtagcttct
    10861 ggttgtcttg aatgcggaat gcttcgccgg tagtgaactc cgacctgaga agcgtatatt
    10921 gcaatccggt ttccagactc caacgctcat tcaatttctt gctgagagag agtcccacaa
    10981 cgatgggggc atgatgttgc tggttctcaa caatcctgcc gctgttattc tgggcaatct
    11041 gcatgagtcc gatggaatct tttcccagag taccctgctg atagcgggtg tgcagataag
    11101 aataatactc ttcccacgtg ctgacttgtt gagggaagtc acttgaaatg ccgtcggtat
    11161 gtggagtggc aatcagctta tataagttct gtgccagttg cggtccgagt gaacctgcca
    11221 gcatcaactt ccattttccg gatttcttct tgcgggttgg cggcatcagg gaaggggaga
    11281 agacgaaagc catctgtcgg ttggtgatgg tctgtccggt gaatggagaa ggtatgggat
    11341 atttgtggat actatctttc attgtgggta tggcaagggg ccattctgtg gaaactggaa
    11401 cgggagggat gattcgttcc cttttgttca gattttcttt ggtatagcat tgttcgtcgg
    11461 ttcggggagt atcggttttc tttgtttgtt gcgtactccc ggcttgcctg gaagaaactt
    11521 tggacaaacg gttttccctg atactctttt tctctctgta cagatagtca tacagcgttg
    11581 gaaagagaag caatactgtc aaaacaatga atacacggta tcctgccagc atctttttaa
    11641 gtaaaatttt cgcccggaac aattgggagg aagaggagtg tggcgctata cccagtaaat
    11701 ctccgatttc tttgtgggac aatccttcca gtactgccag tttaaatacc ttgcagtagc
    11761 cctccggaag gctctccact atatccagca tcttatcgta cgaaatgaaa tccggacaaa
    11821 aaggattttc agcaggctct tcctcttccg gaatatctgt caatgggatg gtggggttgg
    11881 cattggcatg gttgaggtat tgcagtgcca ggtttctcat aatctttttc atccagtatt
    11941 ccagtttctc cgggttgcgc agcgaatgaa tggaagtgaa tatgatgaca aaaccgtcgt
    12001 gaagaagatc ttgggctatc gttgggtcgg gaatatagcg tagacatact ttcagcattt
    12061 tctctgaata gttttcgtag agcaggctca aggcctgccc gtttcccttc tggcataaag
    12121 tgacaagagc ttttgtatcc atgtgtttgt ctcaatgtta tttcttaagg atagagaaga
    12181 acatgaatga ctgcatggat ttttattttt taactaagcc tcccggttga cttctgctgc
    12241 acagtccgga caaatgcctt tcagtacata gttgatgctg ttcagtgtaa atccttgagg
    12301 cagcttcacc actggagtgg gaatgttggt gaagca
//
