LOCUS       gnlProkkaMMMEGNHO_542   2791 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMMEGNHO_542.
ACCESSION   gnlProkkaMMMEGNHO_542
VERSION     gnlProkkaMMMEGNHO_542
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:50:40
            Original ID  :: gnl|Prokka|MMMEGNHO_542
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2791
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2791
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2210]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2210
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..2791
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2791
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             3..2210
                     /NRPS_PKS="Domain: AMP-binding (1-327). E-value: 8e-74.
                     Score: 240.5. Matches aSDomain:
                     nrpspksdomains_ctg542_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (435-494). E-value: 2.4e-10.
                     Score: 32.7. Matches aSDomain:
                     nrpspksdomains_ctg542_1_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     233.2; E-value: 7.4e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg542_1"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-84, bitscore:
                     268.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.5e-12, bitscore:
                     32.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSNEVG
                     GIPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNPKGVRISYRNLDTFTR
                     NLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPAGGTLILAGEDERRDISLLDEL
                     IRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVYGPT
                     ENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSLGYI
                     GSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIRGFRIELTEIAERL
                     NRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLRAELPYYMIPNLWQVV
                     DHFQRTINDKIDVRALPAFTSLELKYVPPVHSGEVILCGILKEMLGLPQVSVEADLIDD
                     LGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRRLLLVPRHEPIYWYRQQNLKKPVII
                     LVCGSAYFNHLYFNLADRLYPKYDFLVVDAIYDHFNKVATDIPELLEYYVRTVQPMIRE
                     RTVYALTGFCMGAELAVGLAEMLYRSMGIMPKVFALDGQAWQNPALCQNYPLLVFPGDT
                     DEMVRERNEIINIYFRTTPNLIYQGEVIVLLSGLFHQQAGLSPEESWTEENYRIFRTEY
                     DNCERLWNKYYPNAPVLRLPADHWHFLEGESLEQLITVFLK"
     aSDomain        6..983
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg542_1_AMP-binding.1"
                     /evalue="8.00E-74"
                     /label="ctg542_1_AMP-binding.1"
                     /locus_tag="ctg542_1"
                     /protein_end="327"
                     /protein_start="1"
                     /score="240.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSNEVGG
                     IPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNPKGVRISYRNLDTFTRN
                     LVDKKLYHLSDPANRYLAFASISFDASILELMMCIPAGGTLILAGEDERRDISLLDELI
                     RREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVYGPTE
                     NTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSLGYIG
                     SVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     aSModule        6..1484
                     /complete
                     /domains="nrpspksdomains_ctg542_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg542_1_PP-binding.1"
                     /locus_tags="ctg542_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9..50
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg542_1_0001"
                     /evalue="3.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg542_1"
                     /protein_end="16"
                     /protein_start="2"
                     /score="11.1"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS_motif       231..287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg542_1_0002"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg542_1"
                     /protein_end="95"
                     /protein_start="76"
                     /score="27.0"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       789..875
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg542_1_0003"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg542_1"
                     /protein_end="291"
                     /protein_start="262"
                     /score="27.4"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       948..1010
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg542_1_0004"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg542_1"
                     /protein_end="336"
                     /protein_start="315"
                     /score="36.4"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        1308..1484
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg542_1_PP-binding.1"
                     /evalue="2.40E-10"
                     /label="ctg542_1_PP-binding.1"
                     /locus_tag="ctg542_1"
                     /protein_end="494"
                     /protein_start="435"
                     /score="32.7"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     CDS             2215..2790
                     /locus_tag="ctg542_2"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLTLVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGVISIMILNKTLQQTGVLHHDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNTVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMNLVRRVQTEYSSFIKDILYYIP"
ORIGIN
        1 ctgccattct ggctattttc cggttagggg caacttattt accgatagat ccctcgctgc
       61 cggataatcg taaacggtat atggctgaaa atgcggatat ggttttgttg ttgaccgatt
      121 catcgaatga agtaggtgga attccgtccg tccgccaact ttacctgaat ggggagcaac
      181 tatccgaacc ggttgttggt gactatactg aagttcttcc caatgattgc gcctatatta
      241 tatatacttc cggaacaaca ggcaatccca aaggtgtacg tattagttat cggaatctgg
      301 atacatttac gaggaatctg gtagataaga aattgtatca tttgtctgat ccggcaaaca
      361 ggtatctggc gtttgcgagt atcagttttg atgcttccat attagaactg atgatgtgta
      421 ttccggccgg aggaacattg atcctggccg gtgaggacga acgcagagat atttctttac
      481 tagacgaact gattaggcgc gagaaggtaa atattgcttt ttttcctcct tcgttgctgg
      541 gcatgtttgc cgaccttgac tttccatcct ttaagactct gctctttggt gcggaggcta
      601 ttggtgaaaa gttatttaac aggctgaaac agcagcctta tcggttgatg aatgtatatg
      661 gaccgacaga gaataccgta ctcagtacca tacggattgt aggcaaagat acgtcgtatg
      721 acgatattgg ctatccgctc aagggaactg tctgttatgt tttgtctgaa aacctccaac
      781 agacaactct tggggctaca ggagaacttt gcttgggagg acctcaggtt tcgctgggat
      841 atattgggag tgttcagctg aatgaaaaat cattcatctc gtacgatgga gaacggttgt
      901 acaggacagg tgacttggta cagcagcaac cggacggttc aatacggttt atcgggcgaa
      961 aagatactca ggtcaagata cgtggttttc gtatcgaatt gactgaaata gcagaacgat
     1021 tgaatagaga tccggacgtg gagagagccc acgtagtagt tgttgagcgg aatgggcgtc
     1081 aattattggg agcttatttg caaccctcag tctccggtaa ctttcatccg gaagaggtca
     1141 aagagcgttt gcgtgcagaa cttccttact acatgatacc caatttatgg caggtggtag
     1201 atcattttca gcgtactata aatgataaga ttgatgtccg ggcgctcccg gcttttactt
     1261 cattggagtt gaagtatgtt cctcctgttc attcagggga ggttatctta tgtggaattt
     1321 tgaaggaaat gttaggtttg cctcaagtca gtgttgaggc cgatttgatt gatgatctgg
     1381 gattaacttc gctggatatg ttgaggcttg ttaccgaggc caataaaaaa ggatgtccca
     1441 tcaacgtatc tgcagtttat actgcccgta atctgcgccg attattgctc gttccgcggc
     1501 atgaacctat ctattggtac aggcagcaaa acctgaagaa acccgtaatc attctggttt
     1561 gtggatctgc ctattttaat catttgtact ttaatttggc cgaccgcctt tatcccaaat
     1621 atgactttct agttgtagat gctatctacg atcattttaa taaagtggcc acggatattc
     1681 cggaactgtt ggaatattat gtccggacgg ttcagccaat gatccgggag cgtaccgtct
     1741 atgcgcttac cggcttctgt atgggagctg aactggctgt cggcctggcc gaaatgttat
     1801 atcgctccat ggggataatg ccaaaagttt ttgctctgga tggacaggct tggcaaaatc
     1861 cggctctctg tcaaaattat cctttgttgg tatttcccgg agataccgat gaaatggtac
     1921 gtgaacggaa cgaaatcata aatatttatt ttcgaaccac tcctaatctg atttatcagg
     1981 gagaggttat tgttttgctg tccggattgt tccatcaaca ggcgggattg tctcctgaag
     2041 agtcgtggac ggaggaaaac tatcgtatat tccggacaga atatgacaat tgcgaaagat
     2101 tatggaataa atattatccg aacgctcctg ttttgcgatt gccggcagat cattggcact
     2161 ttttagaagg ggaatcattg gaacaattaa taactgtgtt tttgaagtag atttatgcag
     2221 actgaaaact tcactttagg taagaaagag cttcttattt tgcttggctt gactcttgta
     2281 ctgccttttc caatcaattg ggcattaatc gaactgaatc cgttgactct gatggcgggt
     2341 gcagacgatg tgcccacctg gataggtttc ggcggcagtt atattggagg aatcatcgga
     2401 ggggtcatct caattatgat tctgaacaag acacttcagc agacaggtgt acttcatcac
     2461 gatttgaaac tcctgcagtt agataccata atttatactc agcaacaaga ttggtttacc
     2521 ggtttcaaac aagaactggc agagaatctc aaatctattg atttgtatgt gttgaatacg
     2581 gttgtttcgt ctatatccat gaaaaactat gcatatgcca aagaggtgtt gacagaaatc
     2641 aataaagggc tcgaatatca gatggttgcc gcatcctttt ctttcacttc tacgcattta
     2701 tcatccgaag aaaaaaagta tatgaatctg gtacgccgcg tacagactga atatagctct
     2761 tttatcaagg atattcttta ctatattcct t
//
