LOCUS       c00018_gnlPro..        15870 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMMEGNHO_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:19:42
            Original ID  :: gnl|Prokka|MMMEGNHO_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1177
            Orig. end    :: 17047
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15870
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11177:14732](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13555)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15870
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15870
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             620..1786
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 112.6; E-value: 6.3e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-35, bitscore: 112.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNNSYMKLIPVMLCFFAMGFVDLVGIASNYVKADLGLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDSYLLMLVSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASTLTFGQFVKAIASFLAPYIAMWGAIEAIPT
                     FDLGWRVLFPIYMVVAVVAILLLNATQITEEPEEGKPSTFGQCLALLGKPFILLSFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAAKTF
                     FAISVLCMLAAMFGLFVFQDQAMIYVCIALIGFGNSNVFPIIFSQAMLYMPDKKNEVSG
                     LMIMGLFGGTIFPLAMGVASDAVGQSGAVAVMLVGVLYLMFYTWRIKK"
     CDS             1818..2708
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MNSIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGNDELGDEILEIFREKQLKHQLERVNYPTGTVQVTLDNGGVPCYDIKEGVAWDNIPFT
                     DDLKRLALSTRAVCFGSLAQRDEVSRATINRFLDTMPDMEGQLKIFDINLRQNFYTKEV
                     LRESFRKCNVLKINDEELIIISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGTVSFQETPKVPVADTVGAGDSFTAAFCSSVLKGKSIPEAHRLAVEVSAYVCTQSG
                     AMPVLPEALRNRLND"
     CDS             2895..5618
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.2e-16, bitscore:
                     49.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILFLLGLMLSGLLVSCSPDAPRYTIGVSQCSDDTWRHKMNDE
                     IQREALFYGGVKVETRTAHDDSRRQIEDIRYFIRQKVDLLIVAANEGMALTPVVEEAFD
                     KGIPVIMVDRRILSDKYTAYIGADNYELGKAVGNYIAHRLKGRGKVVELSGLVGSTPAI
                     ERHQGFMSAISQYPDMTLLASEDAGWLQQPAEAKMDSLLQRFPEIDAVYGMNDRMAAGA
                     FRAAGRRGREKEMIFVGIDALPGKGNGVELVLDSVLDATFIYPTEGDKVVQLAMDILEK
                     KPFERETKLKTAVVDAVNAHVMELQTNHIGELDGKIETLNDRVGIYLSRVATQRIVLYG
                     GLIILLLIVGLLIVVYKSLRSKNRLNRELSRQKEQLEEQRDQLIELSHQLEEATHAKLV
                     FFTNISHDFRTPLTLVADPVEQLLADPSLEGDRRRMLLLVQRNVQILLRLVNQILDFRR
                     YETGKMEFTPVPLDLLQCFVEWNDSFQAAARRKHIHFSFDSMPDTDYHTQADAEKLERI
                     YFNLLANAFKFTPENGKVTVRLAALQKDSVPFFRFTVANTGSLISAEHIRSIFDRFYKI
                     DRHHTGSGIGLALVKAFVEIHGGSISVESDERLGTVFTVDLPVRTCEEGACVVTAPMEE
                     SAPDRVDSLLREDGAENLNDPSKPSVLVIDDNADIRAYVHTLLNSEYSIIEAADGTEGI
                     RKAMKYVPDVIISDVMMPGIDGIECCRRLKGELQTCHIPVILLTACSLDEQRIQGYAGG
                     ADSYISKPFSSQLLLTRIRNLIESRQRMKQFFGDRQTLAKEDICDMDKDFVERFKSLIE
                     VKMGDSELNVEDLGKEMGLSRVQLYRKIKSLTNYAPNELLRMARLKKAASLLASSDMTI
                     AEVGYEVGFTSPSYFAKCYKEQFGESPTEFLKRSGL"
     CDS             5649..5993
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MKDYKENKSNLSETFCNEVYSVVREIPAGSVTTYGDIAALLGMPQ
                     YSRMVGRALRQVPAGLNLPCHRVVNAIGRLVPGWDEQRRLLDAEGVSFRKNGCVDLRLH
                     RWRDDSVLAD"
     CDS             6328..7554
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MSKITIKDLYLIFGNDKQHALRMLKEEKSKSEILKATGCTVAVKD
                     ANLSIREGEIFVIMGLSGSGKSTLLRCINRLIKPTSGEVIINGRDISNVTDKELLRIRR
                     KELAMVFQHFGLLPHRSVLHNIAFGLELQGVKKQEREQRAMESMQLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRIQMQDELLTLQSKMKKTIVFITH
                     DLNEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANAYVERFVQSVDRSKIITAASVMVD
                     KPLVARLKKEGPEVLIRKMLERNLTVLPVVDVNNVLVGEVRLKDLLRLRQDQVKSIESV
                     VREEVHSVLGDTILEDILPLMTRTNSPIWVVNETREFQGVVPLSSLIYEVTGKNKQEIN
                     EIIQNAIEL"
     CDS             7551..8375
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 96; E-value: 7.4e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.4e-30, bitscore:
                     96.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETLINWMMIHFSTFFDALNLGIGSFINGFQHILFGIP
                     FYLTIAAMVLLAWAKAGRGVAVFTLLGLLLIYGMGFWEATMQTLALVLSSTCLALIVGV
                     PIGVWTANSNRAEKVIHPILDLMQTMPAFVYLIPAVLFFGLGVVPGVFATIIFAMPPVI
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMVRRKDKK"
     CDS             8422..9249
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="LLLLAVMCVACNPDSGKKKISIAYANWLEGIAMSHLAKVVLEEKG
                     YEVELLNADVAPVFASVSRKKADVFMDAWLPVTMKDYIDQYGDQIEFIGEVYDSARVGL
                     VVPQYVTIDSIGELAAHKGQFSSEIVGIDAGAGIMKTTDKAIGDYGLDGYKLLTSSSST
                     MLASLQKAMEKEAWIVITGWTPHWMFDRYPLKFLHDPKGTYGNVESIYVVGWKGFTEKD
                     PFAAKFFSNIKFTTEEISSLMKALKDARMDEEDLVRKWRDEHRELVESWIPES"
     CDS             complement(9291..9863)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MNKKFKFCETLCYFVVPPKNGIIMNITIRPTRLEELGQVMPFYER
                     ARRFMAANGNANQWINGYPSPDDIRQDIENGSSYVFVNENQELEGCFAFIRGEDPNYKV
                     IKDGAWLNDAPYGVIHRIASGGRVKGLMDLCLKWCSSHCPNLRVDTHRDNKVLQNILLK
                     NGFTYCGIIYVKNGTERLAYQRTAVTR"
     CDS             complement(10001..13555)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_10"
                     /sec_met_domain="PFOR_II (E-value: 2e-19, bitscore: 59.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-82, bitscore: 266.8,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.7e-32, bitscore: 101.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.2e-13, bitscore:
                     38.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.1e-12, bitscore: 37.6,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-05, bitscore: 14.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5e-26, bitscore: 80.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLVDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLTSQGEKVGLVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANSE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIIAVFKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEAEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDDPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKVENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFEMLKAVGKQFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQADNWTYCADNVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLYGDREMVANATGCSSIYSGSVPSTPYTTNAKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNAPAEAKEVLKAWIENMYDADKTKE
                     LAPQIEAIIEQGIAAGCPISKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEAEGKNPFTLDSKEPNWDDFKGFLKGEVRYASVMKQYPAEAEELFQAAEDNAK
                     WRYNNYKRLANQAWGAAE"
     CDS             complement(13592..14152)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MDYEKLEQLKRLHDSGALNDEEFEKEKKKILDEEATAKPTAVLPM
                     GLTENAYLALMNFAMFIPYVGWIAPIVFWIMGKENSILVNRQGKYILNWYISWFLYGIA
                     LTVLFVIFMFSGILSINDMDYANDQTSPLAVLLGIFGGGAGILLLLILGIGCFLCLLFP
                     IIGGIKGLNGKTWKYPLSIPFLK"
     CDS             complement(14171..15349)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="METFYRTHAYLVEHTNAPVRRDLMDEINWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPDWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIVKSYNLRGFSFREFLNLQTGMKFR
                     HYTLEEILSSHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMLHNPNLMYSIYPVKVEEQDVLDTFFVNTMWKDHKVHKGD
                     KNTSFMVDEVMPFKICCEGAKIKNNPGVTYALHKAEIGRGNQIPLWMFGFLY"
ORIGIN
        1 acaagatggg gatatctata tggctgccgc cccggtggaa gagaccaagt cattgcgtaa
       61 agaatcccgg gagattccgg cttttgaggt gggggatgct tatcatgtcg attcgttgtt
      121 gtccgataat aaaggggctt acgaaataga gttggaactg gcagccggct ctgccgagat
      181 tatgggactg aagctgttca atgaaaaggg ggagaatgtg gatatctaca tcagccttcc
      241 ggagaaaaag ttggtgatgg accgtacgaa gagcggcatc gtagacttcg gcaaagacag
      301 tgccccgcat gccatcgagg cacacgatcg ccggaaacag aactctatta attatgtaga
      361 cgattttgct ttgggtacct gggctccggt gcagaaagcc ggtaactata aattggatat
      421 ctttgtagat aaatgctcgg tagaaatctt cctgaacgga ggtaagattg ctatgacgaa
      481 cctgatattc cctacaactc cttacaatca gatgagtttc tacagtcgtg ggggagcctt
      541 caaggtggat cggtgcaaga tatacaggtt gtagttcctc tatcgcctcc cgttgagaca
      601 ttcattaaat taacatatca tggaaaatac caaaaacaac tcttacatga aactcatccc
      661 ggtgatgctc tgcttctttg ccatgggatt cgtagatctg gtgggcattg cctccaacta
      721 cgtcaaagca gatttgggac tgacggactc acaggcaaac atctttccgt cgctcgtttt
      781 cttctggttc ctgatcttct ctgtacctac ggggatgctg atgaaccgca tcgggcgtaa
      841 aaagaccgtg ttgctcagtc tggtgatcac tttcgcatca ttactgctac cggtctttgg
      901 tgatagctat ttgctgatgt tggtctcttt ctcgttgctc ggcattggca atgcgttgat
      961 gcagacatcg ctcaatccgt tgctgtcgaa catcgtgagc ggcgagcgct tggcaagtac
     1021 cctgaccttc gggcagtttg taaaggccat cgcctccttc ctagcccctt atatcgctat
     1081 gtggggagct attgaggcca tccctacctt cgacttaggc tggagagtgc tgttccccat
     1141 ctatatggtg gtggctgtag tcgctatttt gttactcaac gccacgcaga tcaccgaaga
     1201 accggaagag ggcaaacctt ccactttcgg tcagtgtctc gctttgctgg gtaaaccctt
     1261 cattctgctc tcgtttttgg gcattatgtg tcatgtgggg atcgatgtgg gtaccaatac
     1321 tacagcaccg aagattctga tggaacgtct gggcatgact ctggcagatg ccgggtttgc
     1381 gaccagtctt tactttattt tccgtacggc aggttgtttt ctgggagctt tcattttgca
     1441 gaagatggcg gctaaaacct tcttcgctat cagtgtgttg tgtatgctgg ccgccatgtt
     1501 cgggttgttc gttttccagg accaggcgat gatttatgtc tgtattgccc tgatcgggtt
     1561 tggcaactct aatgtattcc ccatcatttt ctcgcaggca atgctctata tgccggacaa
     1621 gaagaacgag gtttccggcc tgatgattat gggacttttc ggtggaacga tcttcccgct
     1681 ggcaatggga gtggcttcgg atgctgtggg acaaagcgga gcggtagcgg taatgctggt
     1741 cggagtactc tatctgatgt tttatacatg gagaatcaag aaataaccgg atttatagat
     1801 aaaaattaat tcataccatg aacagtataa tcgtaggaat gggcgaagcg ctatgggatg
     1861 tgctgcccga aggaaagaaa atcgggggag ccccggctaa ttttgcttat catgtgtctc
     1921 agtttggttt cgacagccgc gttgtcagtg cggtaggaaa tgacgaactg ggtgacgaga
     1981 ttctggaaat attccgggag aaacagttga agcaccagct cgaaagggtg aactacccga
     2041 ccggaacggt gcaggtgact ctcgataacg gcggagtgcc gtgttatgac atcaaagagg
     2101 gagtggcatg ggataatatt cctttcacag acgacttgaa acggctggct ttgagtacac
     2161 gtgctgtctg tttcggttcg ttggcacagc gcgacgaggt gagccgtgcc actatcaacc
     2221 gcttcctcga caccatgccc gacatggaag gacagttgaa aatattcgat atcaaccttc
     2281 gtcagaactt ctacaccaag gaggtcttgc gtgaatcttt ccggaagtgc aatgtgctga
     2341 agattaatga tgaggaattg attattatca gccgcatgtt cggttatccc ggcattgacc
     2401 tgcaggataa atgttggatt ctgctggcca agtacaacct gaagatgctg atcctgactt
     2461 gcggaacgaa cggaagttat gtattcactc ccggtacggt ctctttccag gagacaccga
     2521 aagttccggt tgccgatact gtgggggcgg gtgattcgtt tacagcggct ttttgttcat
     2581 ctgttttaaa aggaaagagt atccctgagg cacatcggct ggcggtagag gtatctgctt
     2641 acgtatgtac ccaaagtgga gcgatgcccg tacttccgga ggctttgagg aatcgtttga
     2701 atgactaatg tgttggttta tatagggtta ttgattggtt aatagaaagt tccgttgggt
     2761 ttaaaatcag gagagtgttt cataactcac ctttttttaa accaacgaga ctttggtttt
     2821 aaaccaagca ggtgggagat tccggaggga aattgttata tttgcctccg gaacttttta
     2881 tgtaataacc gaccatgaac cgtatacttt tcttactcgg actgatgctg tcgggactgc
     2941 ttgtctcgtg cagtccggat gctccccgat ataccatcgg tgtgtcacaa tgcagtgacg
     3001 acacctggcg tcacaagatg aatgacgaga tacagcggga agctttgttc tacggaggag
     3061 tcaaagtaga gacacgtacg gcgcatgacg acagccggcg tcagatagaa gacatacgat
     3121 acttcatccg gcagaaggtt gacctgctga ttgtagcagc caatgaagga atggctctca
     3181 ctccggttgt cgaggaggct ttcgataaag gaataccggt gattatggta gaccgcagaa
     3241 tactttccga taaatatacc gcatacatcg gagccgacaa ttatgagttg ggcaaagccg
     3301 tcggcaatta catagcccat cgcctgaaag ggcgcggaaa agtagtcgaa ctgagcggac
     3361 ttgtcggttc tactcccgct atcgagcgcc atcaggggtt tatgagtgcc atcagccaat
     3421 atccggacat gaccttgctt gccagcgaag atgcaggatg gctgcaacaa cctgccgagg
     3481 caaagatgga ctcccttttg caacgttttc cggagatcga tgccgtatat ggaatgaatg
     3541 accgtatggc tgcaggggct tttcgggctg ccggtcgtcg aggacgggag aaggagatga
     3601 tttttgtggg catcgatgcc ctgccgggta aggggaatgg agtggaactg gtgctcgaca
     3661 gcgtactgga tgccaccttt atctatccca ccgaagggga taaagtggtg caactggcaa
     3721 tggatattct tgaaaagaaa ccttttgaac gggaaacgaa gttgaagacg gctgtagtcg
     3781 atgcggtaaa cgcgcatgtg atggagttgc agacaaacca tatcggtgag ctggacggaa
     3841 agatcgagac actgaacgac cgtgtgggga tatatctctc gagggtggct acgcaacgga
     3901 tagtgttgta cggaggcctg atcatcctgc tgctgattgt cgggttgttg atagtagtat
     3961 ataaatcgct tcgttccaag aatcgcctga accgggagct gtcacggcaa aaggagcagt
     4021 tggaagagca aagagatcag ctgatcgaac tttcccatca gttggaagag gctacccatg
     4081 ccaaactggt tttcttcacc aacatttcac atgatttccg tactcctctc actttggttg
     4141 ccgatcctgt ggaacagcta ctggcagatc cgtcgctgga aggtgaccgg cgtagaatgt
     4201 tgttgctggt gcaacgcaat gtgcagatcc tattgcgttt ggtcaatcaa atacttgatt
     4261 ttcgcagata cgagaccgga aaaatggagt ttacaccggt tccgctcgac ctgttgcaat
     4321 gctttgtaga gtggaatgat tcgtttcaag cggctgcccg gcggaaacat atccacttct
     4381 ctttcgacag tatgcccgat acggattatc acacacaggc agatgcggag aagctggaac
     4441 gcatttactt caatttgttg gcaaatgcct ttaaattcac tccggagaat ggaaaggtca
     4501 ctgtccgtct tgcggctctg cagaaggaca gcgtgccttt cttccgtttc acggtggcca
     4561 ataccggcag cctgatttcg gctgaacaca ttcgcagcat tttcgatcgg ttctataaaa
     4621 tcgacaggca tcataccggt tccggaatcg ggttggcatt ggtgaaagca tttgtcgaga
     4681 tacatggcgg aagtattagt gtggagagtg acgaacggtt gggaactgtc tttactgtcg
     4741 atctgccggt gcggacttgt gaagaggggg cttgtgtggt gactgctccg atggaggagt
     4801 ctgctccgga ccgggtggac agcctgctcc gcgaggatgg agcggaaaac ctgaatgatc
     4861 cgtccaaacc ttctgtcctt gtgatcgacg ataatgccga catccgtgct tatgtgcata
     4921 cgttgctcaa ttcggagtat tcgattattg aagctgcgga tggtaccgaa ggaatccgta
     4981 aagcgatgaa gtacgtcccc gatgtgatta tttcggatgt gatgatgccg gggatcgatg
     5041 gcatagagtg ttgtcggagg ctgaagggag aactgcaaac ctgccacatt cccgttatcc
     5101 tgcttacggc ctgttcgctc gatgagcaac gcatccaggg atatgcggga ggagccgatt
     5161 catacatctc aaaaccgttc agttcgcaac tcttgttgac ccgtatccga aatctgattg
     5221 aatcgaggca gcgtatgaag cagttctttg gcgaccggca gacgctggcg aaagaagaca
     5281 tttgcgatat ggataaagat tttgtggaga ggttcaagtc gctgatcgag gtgaagatgg
     5341 gtgattcgga acttaatgtg gaagatctgg gcaaggagat ggggttgagc cgggttcagc
     5401 tttatcggaa gatcaagtcg ctcacgaact acgctcccaa tgagttgctc cgcatggcac
     5461 gtcttaaaaa ggcggcatct ctgttggctt cttcggatat gacgatagcg gaggtcggat
     5521 atgaagtggg attcacatct ccttcgtact ttgcgaagtg ttacaaggag cagttcggtg
     5581 aaagtccgac ggagttcctg aagagaagcg gattataaag gaactcactg tataaaagca
     5641 atacatccat gaaagattat aaagaaaata aatctaattt gtccgaaact ttttgtaatg
     5701 aagtatacag tgtcgtgcgt gagattcctg ccggtagtgt tactacttat ggcgatattg
     5761 ccgctttgct cgggatgccg caatattcac gcatggtggg gcgtgccttg aggcaggtgc
     5821 ctgccggttt aaacctccct tgtcatcggg tagtcaatgc cataggccga ttagtgcccg
     5881 gatgggacga gcagcggcgg ctgctggatg ccgaaggtgt ttctttccgt aaaaatggat
     5941 gtgtagacct caggcttcac aggtggaggg atgacagtgt gctggccgat tgatactgac
     6001 tcttttgtag gggtttatgt acgtgtaatg cgcctgccgg aaataatgcg atgaaccatt
     6061 tgaacgttcg gcttgtttac ttaattgtct gcatacgcat ctttggaaga tagctgtgtg
     6121 cagatgtgaa attgactttc gggatatagt aaactatctg ttgacaggaa tcctgtctgt
     6181 aataatcggg taaagaaatc atatttgacc agggaacggc ggaatcgtcg cttccccggc
     6241 atcaacttcc ttgctataaa gaagtgcttg ttttcgtgtg tataggtcac ccgatctgtt
     6301 tttttaataa tctaaaccct attatgtatg agtaaaataa cgattaaaga cttgtatctc
     6361 atttttggca atgacaaaca gcatgcttta cgcatgttga aggaagaaaa gagcaaaagt
     6421 gagatattga aggctaccgg atgtacggtg gccgtaaaag atgcaaacct atctatccgg
     6481 gaaggagaaa tatttgtgat tatgggactt tcgggaagtg gaaaatcaac tttgctgcgt
     6541 tgcatcaacc gattgataaa accgacctca ggcgaagtga tcattaacgg gagagatatt
     6601 tctaatgtca ctgataaaga attgctccgt atccgaagaa aagagctggc tatggtgttc
     6661 cagcattttg ggttgttgcc ccatcgctcg gtgttgcata atatagcttt cggactggaa
     6721 ctgcaaggag taaagaaaca ggagcgggag cagcgggcaa tggaaagcat gcaactggta
     6781 ggactgaagg gctacgagaa ccagatggtc ggcgaactgt cgggaggtat gcagcaacgt
     6841 gtcggtttgg cccgtgcgtt ggccaatgat cctgaggtgc tgctgatgga tgaggctttt
     6901 tccgctctcg atcctttgat tcgcatacag atgcaggatg aattgctgac tttacaatct
     6961 aagatgaaga agaccattgt gtttattacc cacgatttga atgaagccat taaattgggc
     7021 gaccggattg ctatcatgaa agatggtgag gtggtacagg taggcacttc ggaagagatc
     7081 ctgacagaac cggccaatgc ttatgtagag cgctttgtgc agagtgtgga ccgtagcaag
     7141 attattaccg ctgcatcagt gatggtagat aaaccccttg tggcccgatt gaagaaagag
     7201 ggaccggagg tgttgattcg taaaatgctc gagcgtaacc tgactgtgtt gcctgtggtc
     7261 gatgtaaaca atgtgcttgt gggagaggtc cgactgaaag atttgctccg attgcgtcag
     7321 gaccaggtga agtcgatcga gtcggttgtc cgggaggaag tgcattcggt gttgggagat
     7381 acgatactgg aagatatttt accgttgatg acaagaacca attcgcctat ctgggtagtg
     7441 aacgagaccc gtgagtttca gggagttgtt ccgttgtcat cgcttattta cgaggtaacc
     7501 ggaaagaaca aacaagaaat caatgaaatc attcaaaatg caatagaatt atgatcaaca
     7561 taggacaata tattgagacg ctcatcaact ggatgatgat acacttctcc acttttttcg
     7621 atgcactcaa cttaggcatc ggtagtttta ttaatggatt ccagcacata ctgttcggca
     7681 ttcctttcta tctgaccatt gcggcaatgg tgctgctggc atgggcgaaa gccggacgcg
     7741 gggttgcagt tttcaccctt ttaggcttgt tgcttattta tggtatggga ttctgggaag
     7801 ccaccatgca gacattggca ctggttctgt catccacctg cctggccctt atcgtagggg
     7861 ttcccatcgg agtatggacg gcaaacagca atcgtgccga gaaggtgata catcccattc
     7921 tcgacctgat gcagaccatg ccagccttcg tctatctgat tcctgctgtt ttgtttttcg
     7981 gcctgggagt ggttccggga gtatttgcta caatcatctt tgcgatgcct ccggtgattc
     8041 gccttacagg gcttggcatc cgtcaggtgc caaagaatgt ggtagaggct tcacgctcgt
     8101 tcggagctac ccgatggcag ttgctttata aagtacagtt gccccttgct ttgcccacca
     8161 tcctgaccgg agtgaaccag acgattatga tgtctctttc catggttgtc attgcggcta
     8221 tgattgctgc cggcggttta ggagaaatcg ttttgaaagg tatcacccag atgaaaatcg
     8281 ggctgggctt tgaaggaggt atagccgttg tcatattggc aattatttta gaccggatta
     8341 ctcagggaat ggtccgtcgg aaggacaaaa aatagaaagg agaaagaata ggatatgcga
     8401 aaatatagaa taataggaag tttgttgcta ctggctgtga tgtgcgtagc ctgtaacccg
     8461 gatagcggga aaaagaagat aagcattgcc tatgccaact ggttggaagg aattgccatg
     8521 agtcatctgg ctaaagtggt gctggaagag aaggggtacg aagtggagtt gctgaatgca
     8581 gatgtagctc ccgtttttgc ctcggtttcc cgtaagaagg cagatgtgtt tatggatgcc
     8641 tggttacctg tgacaatgaa ggattatata gatcaatacg gtgatcagat agagtttatc
     8701 ggagaggtat atgatagcgc gagggtaggg ctggtggtac ctcaatatgt cactatcgat
     8761 tcgattgggg aacttgccgc ccacaaaggg cagttctctt ccgagattgt cgggatcgat
     8821 gccggagccg gtattatgaa aactaccgat aaggctatcg gggattatgg tctcgatggt
     8881 tataaattac tcacctcgag cagctctact atgttggctt ctttacagaa ggctatggag
     8941 aaggaggcgt ggatcgtcat caccggatgg actccgcatt ggatgttcga ccgctatcca
     9001 ttgaagttcc tgcatgatcc gaaaggtact tatgggaatg tggaatctat ctatgtcgtc
     9061 ggatggaaag gatttacgga gaaagatcct tttgcggcaa agtttttcag caatattaaa
     9121 ttcactacag aagagattag ttcgttgatg aaagcactta aagatgcacg catggacgaa
     9181 gaagatcttg tccgaaaatg gcgcgacgaa catcgggaac tggtagaaag ctggatccct
     9241 gaatcataag cagtatatgt gtgtccggga atccaacttc tgatttctgt ctatcgggta
     9301 acggcagtgc gttggtaggc aagtcgttcc gtaccgtttt tcacataaat aatgccacaa
     9361 taggtgaaac cgttctttag gagaatgttt tggagtactt tattgtcacg gtgagtgtct
     9421 acacgcaggt tcggacagtg ggacgaacac catttcaggc ataagtccat caatcccttt
     9481 acccgtccgc cggatgcgat gcgatggatc accccgtaag gggcatcgtt gagccaggcg
     9541 ccgtctttga tgactttgta gttgggatct tctccccgga tgaaagcaaa acagccttct
     9601 aactcttgat tttcgtttac aaacacatag ctgctcccgt tttcgatatc ttgccggata
     9661 tcatcagggg aggggtatcc gttgatccac tggttggcat tgccattggc agccatgaag
     9721 cggcgggcac gttcgtagaa tggcatcact tggccgagtt cttcaagccg ggtggggcgt
     9781 atggttatat tcatgattat tccattttta gggggcacca caaagtaaca cagagtctca
     9841 cagaatttaa atttcttgtt cataggatgt ttaagagaaa aatcttctct gtgagactct
     9901 gtgttactct gtggtgaaac ctattcattt ttgttcaaaa agggggaaag aacctctttt
     9961 agtcccttcc cccttcgaaa gttattatct gatcaaagat ttattcagct gcaccccaag
    10021 cttggttagc cagacgcttg tagttgttgt aacgccattt tgcgttgtct tcagctgcct
    10081 ggaacagttc ttctgcttct gcaggatact gtttcataac tgatgcataa cgaacttcgc
    10141 ctttcaggaa gcctttgaag tcatcccaat tcggttcttt gctatccagc gtgaacggat
    10201 tcttgccttc tgcttccaga gccgggttgt aacgccacaa gtgccagtaa ccgcacttaa
    10261 cagctttttc ttcctcttcc tggctcttac ccataccggc tttcagaccg tggttgatac
    10321 acggagcgta agcgatgatg agtgatggtc cgggatatgc ttcagcttcg cggatagctt
    10381 tcagagtctg agcctgatca gcacccatag cgatctgtgc aacatataca taaccgtaag
    10441 tagtagccat cagaccgagg tcttttttac gtacgcgctt accggaagca gcgaacttag
    10501 cgatagcacc caccggagta gccttagaag actgaccgcc tgtgttagag taaacctctg
    10561 tatccagaac cagaatgtta acgtctttac ctgaagcgat aacgtggtcg agaccgccgt
    10621 aaccgatatc gtaagaagca ccgtcaccac cgatgatcca ctggctgcgt ttcaccagat
    10681 attgagtcag acccttcagc tctttgctga tcgggcaacc tgctgcgata ccttgttcga
    10741 tgattgcttc gatctgcgga gccagttctt tggtcttatc tgcatcgtac atgttttcga
    10801 tccatgcttt caatacttcc ttagcttctg caggagcatt gtcggctgcc aggatttcgt
    10861 tgaacaactt cacgatacgt gcacgcatct tttcgttagc gagttccata cctaaaccaa
    10921 actcacagaa gtcttcgaac agtgagttag cccaagccgg accgtgtcct tttgcgttgg
    10981 tagtatatgg agttgaaggt actgaaccgg aatagataga agaacatccg gtagcgttgg
    11041 caaccatctc gcgatcaccg tacaactgag aaatcagttt cacatacgga gtttcaccac
    11101 aaccagaaca agctcctgag aactcgaaca acggagtagc gaactgagag ttcttcacgt
    11161 tagccttgat gtctaccagg tgttgtttgc tcttcacgtt gtctgcacag taagtccagt
    11221 tatcagcttg agccaattgg ctttcaaggt gtttcatagt cagagccttg ccacccttct
    11281 tcgggttacc cggacagatg tcggcacagt taccgcaacc cagacagtcg agaacgtcaa
    11341 cctggatacg gaatgtcata ccgtcgaatt gtttacctac agctttcagc atctcgaagt
    11401 tggcaccctt ctgctcttca gcgtcgagta cgaacggacg gatagaagcg tgaggacaaa
    11461 cgtaagcaca cttgttacac tggatacagt tttctgcgtt ccattccggt acgaaagcag
    11521 ctacaccgcg tttttcgtat ttagaagttc cctgatacca ggttccgtct tcgatacctt
    11581 tgaatgcaga taccggcagt aagtctccgt cctgagcatt gatagggcga actacttcgt
    11641 tgatgaatgc cgggtcgttg ttttcaacct tggcatcgtc cggcaggtta gcccaagccg
    11701 gatcaacagt caaagtcttg tattcgccac cacggtcaac ggctgcgtag ttcttgttta
    11761 caacgtcttc acccttctta ccgtaagact tcacgataaa cttcttcatc tgttctacag
    11821 cctggtctac agggattaca cctgtgatac ggaagaatgc agactgaagg atagtattgg
    11881 tacggttgcc caaacctatt tcctgtgcaa tctgagttgc gttgatataa tatacagaga
    11941 tattgttctg tgcaaagtat ttcttcacct tgttaggcag gttcttagcc agctcttcgc
    12001 cttcccagat agtgttcagc aagaacgaac cgttcttacg cagaccacgg gttacgtcgt
    12061 acatgtgcag gtaagcctga acgtggcaag ccacgaagtt cggagtgttt accagatagg
    12121 tagaacggat aggatcgtca ccgaaacgca ggtgagagca agtgaaacct cctgacttct
    12181 tagagtcgta agagaagtat gcctgacagt gtttatctgt gttgtcaccg ataattttca
    12241 ctgagttctt gttggcacct actgtaccgt cagcacccaa gccgtagaat ttagcttcga
    12301 acataccttc gccacccaga gcgatttctg cttcctgagg aagagaagtg aaggttacat
    12361 cgtctacgat accgattgtg aagtggttct tcggcatcgg catagccaga ttcttgaata
    12421 cggcgatgat ttgtgccggg gtagtatctt tagaacccag accgtaacga ccgcctacga
    12481 taaccggagc attttctgcg ccatagaagc agtctttaac atccagatac agaggttcac
    12541 tgttagcacc cggttctttt gtgcgatcga gtactgcgat tgttttagct gttttaggta
    12601 cggcggccag gaagtgttta gcagagaacg ggcggtatag gtgaactgca accaaaccga
    12661 ctttttctcc ttggcttgtc agatagtcga tagcttcgcg ggcagcttct gttacagaac
    12721 ccatagcgat aattacgcgt tctgcatctt ctgctccgta gtaatcgaac aaaccgtatt
    12781 tgcgacctgt gatcttagaa atttcattca tgtattcctc tacgatggcg ggaacagctt
    12841 catagtagtt gttgcatgat tcgcggtgct ggaagaagtg gtcagggttt tcggccatac
    12901 cacgggcaac cggattcatc ggattcagcg cacgtgcacg gaattcggca agcgcttcct
    12961 ggtcaaccag cggagcaagg tcttcatttt ccagcatttc gatcttctgg atttcgtgtg
    13021 aagtacggaa accatcgaag aagttcatga aaggaacacg ggctttgatt gtggcaaggt
    13081 gtgcaacacc ggccaagtcc atcacttcct gtacagaacc ttcagccaac atagcgaaac
    13141 ctgtctggcg cgcagacatt acgtcctggt ggtcaccgaa aatacacagt gcgtgagaag
    13201 ccagtgtacg agcagataca tggaatacgc aaggcaggaa ttcaccggca atcttataca
    13261 tattcgggat catcaaaaga agaccctgag aagcagtgta agtagtagtc agtgcaccgg
    13321 cctgaagaga accgtgaaca gcaccggctg caccaccttc agattgcatt tcctgtacca
    13381 atactgtttc gccgaagatg ttcttacgtc ctgcggcagc ccattcgtct acgtattcag
    13441 ccattgtaga agagggagtg atggggtaaa tggcagctac ttctgagaac atatatgaaa
    13501 tatgtgcagc agcctgatta ccatcacatg tgatgaattt cttctgttta gtcataacta
    13561 aaaataatat ttaagtaagt aatttatttg tttatttcaa aaacggtatg gaaagcggat
    13621 acttccatgt ttttccgttc agtcctttga tgcctccgat gatggggaac agcagacaaa
    13681 gaaaacagcc tattccaagt atcaggagga gcaagattcc ggcacctcca ccgaatatac
    13741 ccagcagaac tgctaacgga gaagtctgat catttgcgta atccatgtcg tttatggata
    13801 agattccgct gaacatgaat attacaaaaa gtactgtcag cgcgatgccg tacaggaacc
    13861 aactgatgta ccagttcaga atgtatttgc cttggcgatt gacgagtata gaattctctt
    13921 tacccatgat ccagaataca ataggggcaa tccagcctac gtatggtatg aacatggcga
    13981 aattcatcag tgccagataa gcattttccg tcagtcccat aggaagtacg gctgtaggtt
    14041 tagccgtagc ttcttcgtcc aatatctttt tcttttcttt ttcgaactct tcatcgttca
    14101 acgctccgct gtcgtggagg cgttttagtt gttcaagctt ctcgtaatcc ataatgttca
    14161 agatttgatg ttaatataaa aagccgaaca tccagagtgg tatctgattg ccacgaccta
    14221 tttctgcctt gtgcaaagca tacgtcactc cggggttatt cttaattttt gctccttcgc
    14281 agcatatttt gaacggcatt acttcgtcaa ccatgaacga ggtgttcttg tcacccttgt
    14341 gcactttgtg gtctttccac atcgtgttta caaagaaagt gtccagcaca tcctgttctt
    14401 ccacctttac ggggtagatg gagtacatca ggttggggtt gtgcagcata atcttcgagg
    14461 gctttttagg aaactcttcc cctttgggat agaccaggtt gatcagccgt gcgtcggcca
    14521 gatacttgat gtagttcatc accgtggcgc gtgatgtctg tatgtcgctt gccagttggc
    14581 ttacgttcgg agcctttggc ccgtctacgg ccaacaaata taataatttt tttatcttcg
    14641 agagatattt tagctcaatt tgtttgataa gcaggatatc tacttctacc atcatgttca
    14701 tggtcttgag cagattctca gagaaattgc gtttctcgag gaagaagggg tagaagccgt
    14761 gatggaggta gtcttgaaaa taatccaaag ggcggacttt ggaaagcacc cctttggcta
    14821 tctgttcgtg gctgctcaat atctcttcga gtgtgtagtg acggaatttc atccctgttt
    14881 gcaggttcag aaattcgcgg aacgaaaaac cgcggaggtt gtagctcttc acgatgtcac
    14941 gcaattccag gttttcttct ttgagccgca tgacggacga accggtgaat acaatcttca
    15001 ggttggggaa acggtcgtag cacatacgta gctcgcggct ccaatcgggg tgcttgaata
    15061 cttggtcgat cagcagaacc ttcccaccgc gtttctgaaa ttcattggcg aaatcgacaa
    15121 tgctgtgtcc ggagaagtag aagttgttca tgttgataaa gaggcacgaa cggtcggttc
    15181 cgaacttctc cttggcgtat tgaagcagga aagtggtttt tcccacgcca cgtgttcctt
    15241 tgataccaat caagcggtca ctccagttta tttcgtccat caggtcgcgg cggaccgggg
    15301 cattggtgtg ctcaacaagg taggcatgtg tgcggtagaa tgtttccatc tcttatcttg
    15361 ggtttttcgg ggggcaaata taagcctttt tttagaaatt gcaaagtaga gatagcaaaa
    15421 ttgtggtttc gtttagcaag tttatctttt gcttcacttt gtcaaaacgg tattcctgat
    15481 aggtggcagg ggcgttattt cggggcaatg gcaagctact tctgaaaaaa cgcagccatt
    15541 tcaatcgggc aattgtgatt ttgcttgtct acttcagtgt ttgcttgcaa atataaatat
    15601 tgttttttgt tttcggtagt ttctgccggt atttatttga aaaagggttt cttttgtcag
    15661 ttcgaaatgt ttgctccgga gagagcaaat agagacggag aaggggaaaa gagcctttgt
    15721 tgacgggctg tcaatcctca ctccgggaga tatgaaggct ttgccccgaa gaagtgaagg
    15781 ctttacccgg gggaagtgaa ggctttgtcc ggcggaaagt gacggtttgc cccgcataaa
    15841 gtgacctgtt tcccggtttt atatgcgttt
//
