LOCUS       c00026_gnlPro..        14017 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMMEGNHO_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:19:42
            Original ID  :: gnl|Prokka|MMMEGNHO_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14017
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14017
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[52:4691]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      53..4691
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14017
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14017
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             53..457
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.6e-24, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             583..2136
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_2"
                     /sec_met_domain="CT_Btheta (E-value: 2.4e-291, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             2157..3071
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="OAD_gamma (E-value: 1.5e-16, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             3097..3528
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 9.4e-23, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             3531..4691
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="OAD_beta (E-value: 4.7e-154, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             4840..6171
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLVQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             6185..7477
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKAMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIEDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             7981..9831
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="Alpha-amylase (E-value: 6.5e-64, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             9986..10426
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGTEMEASRITECIEDLKRLHEVLNEI"
     CDS             10439..11506
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_10"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 4.3e-12,
                     bitscore: 35.5, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDQEYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             11511..13106
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_11"
                     /sec_met_domain="MFS_1 (E-value: 9.5e-15, bitscore: 43.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFSEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(13201..14016)
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="NATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKSCIDS
                     GFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTEP
                     DEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGVMKEL
                     PGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLA
                     MTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gttttatacc attccgaaaa gacgattaat accaaaattt aaaaatatag ttatgaagat
       61 ttcacacatt gaacatttgg gcattgccgt aaaaagtatc gaagaagccc ttccgtatta
      121 tgaaaacgtt ttaggtttga aatgctacaa catcgaaact gtagaagatc aaaaagtaag
      181 aacagccttc ctgaaagtag gtgataccaa aatcgaatta ctggaaccca catgtccgga
      241 aagtaccatc gcgaaattca ttgaaaacaa aggtgcaggt gttcatcacg tagcattcgc
      301 cattgaagac ggcgtagcca atgccctggc cgaagccgaa agcaaagaga tccgcctgat
      361 cgacaaagct ccgcgcaaag gtgccgaagg cctgaacatt gctttccttc acccgaaatc
      421 aactctgggc gtactgacag aactctgcga acactaaaaa gatgtacgat tcggacgatc
      481 cgcgccacgg acaaacggaa tttttctttg cattaaattc cccatccggg ttgtcaatcg
      541 tcctgttgta aatattataa ccctttaaat taagaaaaac tcatgagtaa ccagcttgaa
      601 aaagtaaaag agcttattga acttcgtgct caggctcgtt taggtggtgg cgaaaaggct
      661 attgaaaaac aacacgccaa aggcaaatat acagcccgcg agcgtattgc acagttgctt
      721 gacgaaggta gtttcgaaga actggatatg tttgttcaac acagatgtac caatttcgga
      781 caagagaaaa aacatttcct cggcgacggt gtggtaaccg gttatggaac gatagaaggt
      841 agattagtat atgttttcgc acaagatttc acagtattcg gtggttcact gtcggaaacc
      901 atggcacaaa agatctgtaa agtaatggat atggccatga agatgggtgc ccctgttatc
      961 ggtatcaacg actcgggtgg cgcacgtatt caggaaggca tcaacgccct gtccggttat
     1021 gctgaaatct tccagcgcaa catcatggct tcgggtgtca tcccacagat ttcaggtatt
     1081 ttcggtccgt gtgccggcgg tgcggtttac tctcccgccc tgacggactt cacgctgatg
     1141 acggaaggta catcttacat gttcctcacc ggaccggctg ttgtgaaaac agtaacgggt
     1201 gaagacgtgt ctcaggaaga tctgggtggt gcaagcgtac atgccagcaa gtccggtgta
     1261 actcacttca ctgccgaaac cggtgaagaa ggtctggcga ttattcgcaa gcttctcagc
     1321 tttattccgc aaaacaacct ggaagaagct ccattggtga actgtaccga ccccatcgac
     1381 cgtatggacg acctgctgaa cgagatcatc cccgacagcc cgaacaaacc gtacgatatg
     1441 tacgaagtga tcggcgccat catcgataac ggagaattcc tggaagtaca gaaagactat
     1501 gcgaaaaatc ttattatcgg ttttgcccgt atgaacggac aatcggtagg tgtggttgcc
     1561 aatcagccta aatacctcgc cggagtactc gacagcaatg cttcacgcaa aggtgcacgc
     1621 ttcgttcgct tctgcgacgc attcaacatt ccgctggtga cattggtaga cgttccggga
     1681 ttccttccgg gtacgggtca ggaatataat ggtgtaatcc tgcacggagc caagttgctg
     1741 tacgcttatg gtgaagccac tgtgcccaag gtaactgtta ccctgcgtaa atcttacggt
     1801 ggttcgcaca tcgtaatgag ttgcaagcaa ctccgcggcg acatgaacta tgcatggccg
     1861 acagccgaaa tcgccgtaat gggcggtgcc ggtgcagtag cggtattgta tgccaaagaa
     1921 gccaaagatc aggaaaaccc tgctcaattc ctggcagaca aggaagccga gtacactaaa
     1981 ctgttcgcca acccgtacaa tgcagccaaa tacggttaca tcgacgatgt tatcgaaccg
     2041 agaaacactc gtttccgcgt gatccgcgcc ctgcaacagc tgcagaccaa aaaattaacc
     2101 aaccctgcta aaaagcacgg taatattcca ttgtaacaaa ttaaacatcg attgttatga
     2161 ataagaaaag aatcgggata tttatcgctc tgctggcaat ggtttgcatg gggctcaggg
     2221 cgcaaagtgc caccagtctg agaatcaatg aggttttggt cgtcaacgac cagaactatc
     2281 aggatgacta cggactgcac aatgcgtgga tagagatatt caacacctct ttcgcttctg
     2341 taaatctgga aggttgcttt ctgacgaacg ataaaaacaa tccgaccaaa tatcctattc
     2401 ccaaaggcga cgtgctgact ctgatcaagc cgcgccaaca tgctttgttc tgggcagacg
     2461 gaatgcctaa ccggggtacg ttccacgtga actttacgct cgacccgaac aaagagaatt
     2521 acattgcttt gtatgactct aacggtaaaa ctctgattga cgaagtaacc atacccgccg
     2581 gtcagcttgc cgaccgttca tacgctcgcg aaaaagacgg aagtgccaac tgggtagtaa
     2641 aaggtgaagg agaacacagc tatgtcactc cgagcaccaa caatatgact atcgacaaaa
     2701 acccgaagat cgagaacttc aagaaacacg actctatcgg tatcggtatg gccatcatcg
     2761 ccatgtcggt cgtattcata ggtttggtac tcttgtatct ttcattcaag gcggtaggta
     2821 acgtagctgt cagattgggt aagaaaaacg cgatgaaagc caccggtatc accgacaaga
     2881 cggaagcgaa ggaaaagaac ctgggtagcc acacaggtga agaaaccgcc gcaatcgcca
     2941 tggctttgca tgaatacctg aatgacgctc acgacgttga agacatgatt ttgaccatca
     3001 acaaagtgaa acgcacctac tcaccctgga gttcgaagat ctacacactg cgtcagactc
     3061 cgaaaagata attactaacc ctaataaaat gaagcaatga aacaatataa atataaaatc
     3121 aacggcaacc tttacaacgt tacagtgaac gatgtagaag ataacatagc caacgttgaa
     3181 gtgaacggaa cctcttataa agtagagttg gacaagcccg tcaaagccgc tccgaaaccg
     3241 gtgacccgtc cggcagccgc tccgaaaacg gaaacaggtg ctccggtagt aaccaaacaa
     3301 ccgacagctt ccaaaaaaga cggtgtgaaa tctccgcttc cgggcgttat cctcgacata
     3361 aaagtgaaag aaggggatac cgtgaagaga ggccagacga tcatcatcct tgaggctatg
     3421 aagatggaaa acaacatcaa tgccaataaa gacggaaaag tagcagaaat taaagttaat
     3481 aaaggagatt ctgtacttga aggtacagac ctcgtaatca ttgaataatt atgggagatt
     3541 tcgtatcatt cttagggaat aaccttgttg acttctgggg atacaccggt tttgcgaacg
     3601 cgacacccgg acatcttttc atgttgctaa tcggtctctt ctttatctac cttgccgtag
     3661 ccaaagaatt tgaaccgatg ctgctgatcc ccattggctt cggtattctg atcggtaata
     3721 ttccattcaa tatggaagcc ggattaaaag tgggtattta cgaagaaggt tcggtactga
     3781 acatccttta tcaaggagta acctccggct ggtatccgcc gctcattttc ctgggtatcg
     3841 gagccatgac ggacttctcg gcgctgatct ccaaccccaa attgatgctg atcggagctg
     3901 ctgcgcaatt cggtatcttc ggcgcgtata tcattgccct gctcattggg ttcgaaccca
     3961 accaggcggg tgctatcggt atcattggcg gtgccgacgg accgacggcc atcttccttt
     4021 cgtccaaact ggctcccaac ctgatgggtg ccatcgctgt gtcagcctat tcttacatgg
     4081 cgctggtgcc ggtgatacag ccacctatca tgcgtgcgct aaccaccaaa cacgagcgtc
     4141 tgatccgcat gaaaccaccg agaatagtat cgcatacgga aaaagtaatc ttccccatcg
     4201 tgggtctgtt gcttacatgc ttcctggttc cttcgggtct gcctttgctg ggtatgctgt
     4261 tcttcggtaa tcttctgaaa gaaagtggag taacccgtcg tttggcaaat acggccagtg
     4321 gtccgttgat cgatgtgatc actatcctgt tgggactgac tgtgggagct tctacccaag
     4381 cttcacaatt cctcacctgg gattctatct tgatctttat cctcggtgca ttctctttca
     4441 tcatcgcaac agcgtcaggt gtcatgtttg tcaaattctt caatctattc ttgaagaaag
     4501 gcaataagat caatccgctg atcggtaatg caggtgtatc cgccgtaccc gactcggcac
     4561 gtatttcaca ggtaatcggt ttggaatatg atccgaccaa ctatctgctg atgcacgcca
     4621 tgggtcctaa cgtagcgggg gttatcggtt cggctgtagc tgccggtatc ctgctcggat
     4681 tcctcatgta aacgatattt ttttcattag taaggtagac gtccttcttt tcgcaaagaa
     4741 gggcgtcttt tttttgcgtt aatctatcta aaagacatta cgaacctttc gtagaatgga
     4801 tatttttact aacttgcgga caataaaaca atacgtccta tgagaacaag aacaatgaaa
     4861 ccactcttcc ttattttctg tctttgcctc agtcccctac tgatgggcca gaatcaaaac
     4921 aaaattcagg aagcaatggc aaactatgac tacgagactg ccgttgaact gataaacaag
     4981 gaacctccca ccatcccact gttggtgcag aaagcaaaag ccctgaaagg aatcggcagc
     5041 aatgcggaag ctctacgttc catccgccaa gtgatagcgg aagactccac caaccaacag
     5101 gcacacatcg aagcagcgga atgctgtaaa gcaatggcca agtacaacga tgcgctggac
     5161 tactaccgga aagccatcag cctgaatccc aaaaacaagt atgcccgttt gcaattcatc
     5221 aacctgcttt gcaacaccaa aaactatgct gaggcttttg gagaaagttc aatgatgtcc
     5281 gaaacggaca gttcggccgt agtgctccac ctacaggctc aaagccttga agggatgcaa
     5341 cagatactac cggctatcgg ttgctatgaa gtcattcagg ataaatatcc ggacgattat
     5401 ctggctgcgg ccaaactcgg aaacctgaac attgtggctg gatatcccga atatgccatc
     5461 caagctaccg aacgctatag ggaacgggac tccaccaacc tgattgtcaa ccagcaaaac
     5521 gctctcgcct actgccacgc cgaacaatat ccgacagcca tcaagcgcta tgaaaagctg
     5581 tgccaacagg gggacagcag tacacagacc ttatactacc tgggagtcag ctattacgcg
     5641 gatgaatatt attacgaagc gcacgcgtgt ttcagcaaac tgcaaaaaga gatggaagaa
     5701 aatcccaatc tgctctatta tctgggacgt tgctgcgcca agacttcctg gaaaaaagaa
     5761 ggcatcgaac acctggagaa agctatcgaa ctaaccattc ccaaagacag caccatgatc
     5821 cgactttaca aaggcttggt ggattgttgt aaactggctc aggatactcc aaagcaaatc
     5881 caggctctca gagaactgta caaatatgac aagacgaacc ataaacttct ttatgacatc
     5941 gcctggaact attcatatca actcaaagac aacaaatcgg ccgaacgtta tctgcaggct
     6001 ttcttaaaaa cccgaaaggc gaatgccagg aaagaagaac cggtgagtga gaaaggggaa
     6061 cttgtactcg gacttgaaaa ttattacaac gctgccgaaa attggctgaa agacttacag
     6121 aaagaaaagt tcttcaaaga aggaataccg ttagaaagtc agaaacaata gaatctatcc
     6181 ccccatgaaa cattggatac tcctcctcta tctgggcttc agcgtagtgc tgcaagccca
     6241 gaacaccgcc tccgttcaag aagcaatggc aaactatgac tataaaacgg tgatcagact
     6301 gattgatgaa gaaagtgcat caccacagtt actcatacag aaagccaaag ctttaaaagg
     6361 tttagggcgt accgccgaag ccctgtccac tttgcaacat atcattatcg agctgcccga
     6421 aaatcagcag gcattggtag aggcagcaga atgttgcagg caattgagca aatttaacga
     6481 ggccttgggg tattatcgga aggcgatgga actcaatccc gaacatattt acgcacactt
     6541 gcaatacacc cgcttgttat acaactatca gcgatacggc gatgcattgc gtgagagtat
     6601 cgcattggcc aggaaagaca gttccgccac cgtattgcga ctgatggcgg aaagcatgga
     6661 aggagccggc atgccggtag aaagtatgtt ttgctatctt tccatcatca ggaaatatcc
     6721 ctccgactat ctctcggtag ctaagctggg cagtatcttc aatacaatga aagattacga
     6781 aggggcaatt gccctgacag aagcataccg ccggacggac agcaccaatg tagaagtgaa
     6841 ccgtcaaaac gcactggcgt attgtctgcg caaagaatat cccaccgcca tcaaacgtta
     6901 tcaggatctg accgcccggg gagacagcac actgctgaca tgttattatc tgggagtcag
     6961 ctactacgct acgaaagaat actataaagc gcgcgattgg ctgctcaaag caaaatcatg
     7021 ccagtcaccc ggcgccaacc tactctacta tttgggacgt tcgtgctcca agacattatg
     7081 gaaacaagag ggaataggat atctgaacca ggctatcgcc ctgactatcc ccgccgacag
     7141 tatcatggag cgcttatact caggcttggc agactgctac aggcaaacca agcaaacccg
     7201 ggaccaaatc aaggctacca aagaacaata caaatatgcc cctgacaagc atattttact
     7261 ttataacttg gcgttcttat cggacaaaat tgaagatact aaagccacag agcattactt
     7321 gcaggctttt ctgcgaacaa aatccaaaca aaatgcagta ctacagcagc cggatgatga
     7381 cgaagaagaa cccgcaccct acatagatta ctacaaaagt gccaccaata aattggaaag
     7441 catccgaaaa gagaaattct taaagggaga aaagtgaatt gatcggatag atgcatcgtt
     7501 tcggacaatt caccactgag tgcagacaga gtttcacaga gggagaataa tggaaaataa
     7561 atttgaagat gtgcggtaga aggcacagtg gcacgtaacc gaagtcacat cggcacacag
     7621 ccgaaattac tgtgctgtgt agccgaagtt acggtgctgc gtagccaaag ttacggtgct
     7681 gcgtagataa agttacggtg ctgcgtagcc gaagttacgg tgctgcgtaa ataaagttac
     7741 ggtgctgtgt agccgaagtt acggtgctgc gtagccgaag ctatgacggc atctcctttt
     7801 ccggacgtca cgttcacctg attgcatcga aaagtgctcc ttatcggttg agccccatcc
     7861 cggagaattc tccaatgaaa acgtttgcat aaatagatgg cacacagtaa gaaagaaaac
     7921 ggaaaacaat ccgatgattt accctatatt agcaacatta aataataacg agctaatatc
     7981 atgaaaaaat tattgttact cttaggttca ttcctactgt cattaaccac ttatgcagcc
     8041 atgaacatat ccaaaatcga tccgcccttc tggttcaccg gtatgaacaa tccggaactc
     8101 cagttaatgg tatacggtga aggcatcggc caggcatccg tatcagtaaa ttatcccggt
     8161 gtatcgctca gcagcgtcgt gaaactggaa agcaacaatt acctgcttgt ctacctacat
     8221 ctcgataaag aagtaaagcc gggcaagatg cccatcacat ttacggtcgg aaagaagaaa
     8281 ttggtgaaag agtacgaatt gaaagcacgc agcaaagccg gagtcgatca caaaggtttt
     8341 gacgcatcgg atgcattata cctgctgatg ccggaccgtt ttgccaatgg caatccggat
     8401 aacgaccgga tagaaggcat ggccgaatat aaagtggacc gcaacgaccc gaacgcacgt
     8461 cacggaggcg acctggccgg tatcgaacaa aatctggact attttaccga cttgggagtg
     8521 accgcactct ggttcacccc ggtactcgaa aataatatga aaggcggctc atatcacgga
     8581 tatgcaacaa ccgattatta caaggtagac ccacgtttcg gcactaacga ggaatatcgc
     8641 tcactgatag cgaaagccca caaccggggc attaaggtcg tgatggacat gatcttcaat
     8701 cattgcggag tagaacatcc ctggatcaag gacatgcctt caaaggactg gttcaaccat
     8761 gcggacttca agaacaactt tgtgcaaact tcctacaagc tgactccaca tgtagatccg
     8821 tatgcctcgg agtacgattt cgaccagatg aacaacggct ggttcgtgga agccatgcct
     8881 gacctcaacc aaaagaaccc tcacgtatac aaatacctct tgcagaacag cctgtggtgg
     8941 attgagtacg ccgatatcga cggcatccgg atggacacct acccgtatgc cgattacgat
     9001 gccatgagca actggatgaa agaactgaac gaagaatacc ccaactacaa cacggtgggc
     9061 gaaacctggg ttaccgaacc ggcctataca gcctggtggc agaaagactc caaactctcc
     9121 gccccgcgca acagtcactt gaaaacagtc atggatttca gcttcttcga caaagtcaac
     9181 acggccaaga atgaacaaac ggacacttgg ttcaaaggat tggaccgtgt ctacaacaat
     9241 tttgtatacg attatctgta tcccaatccg gcttccgtac tggctttcat cgagaatcat
     9301 gacaccgacc gtttcttggg tgaaggcgaa aacctcgata tgctgaaaca ggcctccacc
     9361 cttttattga ccacccgacg catcccgcaa ctctattatg gaacggaggt gatgatgaac
     9421 ggagtaaaga gtaaaagcga cggctatgta cgaaaggact tcccgggcgg atggacggac
     9481 gataaagaga atgccctgac tcccgaggga cgtacccgat tgcagaatga aagctataac
     9541 ttctaccgca acctgctgaa ctggcgtaag ggcaacgatg tgatcgccaa aggcagcatg
     9601 aaacagttca tggtgcagca cggcgtatat gcttatgcac gccaatataa agggaaaacg
     9661 gtattcgtcc tgttgaacgg tacggataaa gaggtgaaac ttcccctgaa atactatgcc
     9721 gaagtgctga aagacaagac tcaaggaaaa gacgtcatta gcggaaaagt aacggcactc
     9781 aatgaagaac tgacaatggc accccgccaa tcgatggtta tagagcttta atctcacacc
     9841 ggttataacc gcataagcaa agggcacaaa ggatttcacc cgacatcctc tgtgcccttt
     9901 gtgtagccta atgctaataa tagtcaaacg tttgactatt atcggagaat attcctacct
     9961 ttgcagcgac taaaagaata cgacgatgac aaacaacgaa tcggagcgcg agctcgtcct
    10021 acaaacctta cgaacctgga tggcattccg ccaggccgtt cagcgggtac tcaaacgcca
    10081 caacgtggat atgaccttcg agatgctgca agtaatgaac tgcctgtgga acaaacaagg
    10141 catcagccag caatccctgg ctgagaaaac agcaaaggac aaggcttgcc tgaccaatct
    10201 gattaataat ctggaaaaga aaaactgggt gatacggaaa gaaggcccct ccgaccgccg
    10261 aaaccgcctg attttcctga cgccccaagg cgaagaactt gccctcaccg tgaaacccct
    10321 gatcaacgat atctatgccc aaaccggaac agagatggag gcaagccgga taacggaatg
    10381 catcgaagac ctgaagagac tgcatgaagt gctcaatgag atctaaaaga aatccgccat
    10441 gtccacccat cagataaagc taaaacaatt gagaagactg aagttcagga acatctttct
    10501 caacacagta tgcatcctgc tggcattggc aggtatttca tggacagtaa actacttctg
    10561 gaaatacgcc cgctacgaga taaccaatga tgccgtagtg gatcaataca tcgctccgct
    10621 aaacatccgg ataccgggct atatcaaaga agtacgtttt accgaacacc agtatgttca
    10681 tgccggcgac acgttactga tactggacga ccaggaatac cggatccggc tgaaagacgc
    10741 ggaagcggcc ttgatggatg ccttgggatc aaaggaagtg ttaaactccg gcatccggac
    10801 ttcaggagta aatgtagccg tacaagaagc caacatagcc gaaacactgg cacgcctttc
    10861 acagcaagaa gcggaactga accgatatac ccggctcctg aaaaagcagg ccgtcagcca
    10921 acaggattat gaactggcca aagcgaactt cgaagcgacc cgggcaagat acaacgccct
    10981 gttgcgacaa aaagaagcgg cccaatcgca gtattccgaa accagcaaac gcagtacagg
    11041 cgccgaagcc aatatcctcc ggaaggaggc cgacctggag atggcccgac taaacctgtc
    11101 gtataccgtt gtcaccgcac cctatgacgg atacacggga cgacgtacac ttgaaccggg
    11161 acagttcgta caaggcggac aaactctttc ctacctggta cggggcaatg acaagtgggt
    11221 gacagccaat tataaagaga ctcaaattgc ccatatctat atcgggcaaa aagtccgcat
    11281 caaagtagat gctttcagcg gacgcacttt tcacgggacc gtaaccgcca tttccgaagc
    11341 caccggatcg aaatactccc tggtaccgac cgacaattcg gcagggaact tcgtcaaagt
    11401 gcagcaacgc attccggtcc gcatcgatct caatgacgcc tcacccgaag agatggaatg
    11461 cctccgtgca gggatgatgg tagaaacgga agcggtccgc ccttaggctt atggtgaagc
    11521 tcaatctgcc tacccgtccc tgggtgcctc aatggttggg catcgtgacc atgtttattg
    11581 tcatctttcc catcaccctg ctcaacggtg cctacacagg aagtatggtc gaagtatcga
    11641 acacgctggg agtattgagc gaagatatta ccatggctta ctattcagct tcggtaggga
    11701 tggctgttgc ctatcccatc gtaccgaaaa tacgcaccat agccactccg aaaaccttac
    11761 tgcttaccga cctgctgcta cagatattct tcagcctggt atgcgccaaa accggtagta
    11821 tggatgtcat catggtatgc agtttctgta tgggatttct caaagccttc gtcatgttgg
    11881 agttcatcat cctgatccgc ccgctcttca gtccgaaaaa cgtacgaagt gaattctatg
    11941 cctacttcta ccccatcgtt ttctccggag gtcagctatc gatggctatc accgctcaac
    12001 tggcctatca ctaccaatgg cagcacatgt actattttgt caccatcctc ttgctgatcg
    12061 ccattctgtt cgtcatctgt ttcttccgct atgcaaggcg tcccatgcac attccgttca
    12121 aagagatgga cggaagaagc atgttcatca tcgccaccgc tttcctgcta acgctctata
    12181 catttaccta cgggaaaaca ctcgattggt tcgcatcccc gaagatcaga gtatatgtat
    12241 tcgtcatccc gctcctgata gctctcttca tccatcggca gcgtacacaa ggcaaaccct
    12301 ttgtcagcct gaaaccactc tttctgcata aatccatcat cggatatggc ttcatggtac
    12361 tcgccatgtt cctgacagcc accagttcac tggtaaccaa ctatatgaac agcatcatcc
    12421 gggtagacag catacacgcc aattcgctga gcctgtggct attgcccgga tatgtggtag
    12481 gggccgtcat ttgcttctgg tggttccgat ggcaacgatg gcggtttcgc ttcctcattt
    12541 caggaggtat gttctgctac gtcatctatc tggctatcct ctactttggt atcacccctt
    12601 atggaactta tgaaatgctc tacctcccca tcctgttccg gggagtgggg atgatggtca
    12661 tattcattgc gttcggtgtg tttgttgtcg aagatttaga cccgcgcctg acgttgtcca
    12721 atgccttctt cctgatttca ttccgctcag tattagctcc ggtcctgtcc gcttcgttct
    12781 ttaacaacat gctttactat ctgcaggcaa aggggatgaa cattctttcg gaaaacatga
    12841 cgctgaccaa tccgctggcc gaacaaaaat acaatcaggc attgagcaat gccctggcgc
    12901 aagggcacga attcagcgag gccggacaat tggcagccaa cagcctgtac tccactttgc
    12961 agcagcaatc cctgctgctt gccctgaaaa ccctaatcgg ctatgtactg atactggcac
    13021 tggtgattgc tgtcatcgca gcgttcattc ctttccataa aacgctgaag gtggctgtag
    13081 tgaagacggg tgacgatatg gtataatgag aagggataca aaaaagccac ccaattgctt
    13141 gagtggcttc ttaaaatata aattagatca agtaaaactt ttaaatacta gatttggaat
    13201 ttattcagct aacttgttgt cagaacccag cacgttgata attttgtgct tgtagagttt
    13261 ttccatattg tcgcgagccg gtcccagata tttacgcggg tcgaactcag ccggtttttc
    13321 tgcgaatacc ttacggatag cagcagtcat agccaggcga gagtctgagt cgatgttgat
    13381 tttgcaaaca gcagacttag cggctttacg cagttcctct tcaggaatac cgatagcagc
    13441 tttcagtgca ccaccaaact ggttgatagt tgcaacctct tcttcaggaa ctgaagatga
    13501 tccgtgaaga acgataggga atcccggaag ttctttcatt acaccgtcca atacgtcgaa
    13561 tgccaacgga ggaggaacca tacggcctgt cttcggatcg atgtggcact gttccggagt
    13621 aaatttgtaa gcaccgtgag aagtaccgat agagatagcc aatgaatcgc aacctgtctt
    13681 ggtaacgaaa tcaactactt cgtccggttc agtatatgtg tggtggtcag aagaaacttc
    13741 gtcttctaca cctgccaata cgccaagttc accttctaca gttacatcga actggtgagc
    13801 gtattcaaca actttcttag tcagagcaac gttttcgtcg taaggaaggt gagaaccgtc
    13861 gatcattaca gaagagaagc ctgagtcgat acagcttttg caagtttcga aagtatctcc
    13921 gtggtcgagg tgcaaaacga tttcaggatt tttgcagccg agttcttttg catattctac
    13981 agcaccctga gccatgtaac gcaacaatgt agcgtta
//
