LOCUS       c00027_gnlPro..        13654 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMMEGNHO_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:19:42
            Original ID  :: gnl|Prokka|MMMEGNHO_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13654
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13654
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7858:13653]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7859..13653
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13654
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13654
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..370
                     /locus_tag="ctg27_1"
                     /transl_table=11
                     /translation="FITVLIGLFFNPMPDKKEIDRNEIKMELIAPDRLEGNYTVSKSIV
                     GQIQVSSGIIKKVKDGTFQLLITGKSSPKVYKLDFNSDKMIFVSGELGNGAIHYDKDLD
                     KIKIVFNINEQTTWTISK"
     CDS             352..1095
                     /locus_tag="ctg27_2"
                     /transl_table=11
                     /translation="MDNFKVIYSIPFLFFIIVSCSNSSTEMVAKSKYDAKIAEYKELNE
                     QQAAVIEDNLEKSKIINNVVTELNQIAGNTHSLRVNVEHGVGELSQAEEINQKLQTLKK
                     RLSAVEGKRSDSSKNLLATMDKLKSIIEQKEIEINNLKQEIANQQQTIANQKNTIASQQ
                     VTIDAQSQELMNKQQEMWYKLGTELHSVVEELPKVKGRKDKRNIKNTRYYILNKAKECF
                     EHAAQLGHSLAGSKARQVEGEMSRL"
     CDS             1171..3435
                     /locus_tag="ctg27_3"
                     /transl_table=11
                     /translation="MSQLPTLIADLALILICAGIMTLLFKKLKQPLVLGYVVAGFLASP
                     HMPYTPSVMDVANIKTWADIGVIFLLFALGLEFSFKKIVKVGGTAVIAACTIIFCMILL
                     GIAVGMGFGWQRMDSLFLGGMIAMSSTTIIYKAFDDLGLRKKQFTGLVLSILILEDILA
                     IVLMVMLSTMAVSNNFEGTEMLGSIGKLLFFLILWFVVGIYAIPEFLKRCRKLMSEETL
                     LIVSLALCFGMVAIAANTGFSAAFGAFIMGSILAETIEAESIDRLVKPVKDLFGAIFFV
                     SVGMMVDPAMIIEYAVPIIVITLAVILGQAFFGTMGVMLAGQPLKTAMQCGFSLTQIGE
                     FAFIIASLGLSLHVTSDFLYPIVVAVSVITTFLTPYMIRVAEPASNFVDRKLPESWRRF
                     LMRYTTGTRTVNHESLWRKLLFALARILVVYSIVSISVITLSFRFVVPLLREHLPGIWG
                     PLAGAVFTILCISPFLRAIMVKKNHSVEFITLWNDNRVNRGPLVSTVVFRVAVSVLFVM
                     FVITRLFKASVGLMFGVALLLVILMILSRQLKKQSILIERKFFQNLRSRDIRAEYLGEK
                     KPAYAGRLLSRDLHLTDFEIPGESAWAGKTLLELNLGKKYGVHVVSILRGKRRINIPGG
                     SIRLFPMDKIQVIGTDDQLNIFAEEMSHVAVIDSGVFEKSEMTLKQLLIDTDSAFLGKT
                     LRESGIRDKYHCLIAGVERGGEALMTPDVNVPFEEGDVVWVVGENEDVYRLIGQNCDRK
                     R"
     CDS             3477..4130
                     /locus_tag="ctg27_4"
                     /transl_table=11
                     /translation="MIQIETILDILVKGFVIGIVVSAPLGPVGVLCIQRTLNKGRWYGF
                     VTGLGASLSDIAYALLTGYGMSFVFDYINKNIFYLQLLGSIMLLAFGIYTFRSNPVQSI
                     RPVSANKGSYFHNFITAFAVTLSNPLIIFLFIGLFARFAFVQPGVLVFEEITGYLAIAL
                     GALAWWFGITFFVNKVRTRFNLRGIWILNRVIGSIVMAVSVFGLIFTLLGESIY"
     CDS             4149..4694
                     /locus_tag="ctg27_5"
                     /transl_table=11
                     /translation="MKIAQQLKEKNIAEYLIYMWQIEDLIRANDCDVDRIEENIVSRYQ
                     VSDEERRELTEWYANLASMMREEGVREKGHLQINRNVIINLTELHAALLASPKFPFYSS
                     AYFKALPFIVELRNKNGQKEEPELETCFEALYGMMLLRLQKKPVSPETTKAMEAISSFL
                     SMLANYYDKDRKGELKLE"
     CDS             4830..5693
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_6"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-105,
                     bitscore: 342.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILVTGANGQLGNEMQVLARENLQYTYFFTDVQELDICDEQAVY
                     AYVSEHKIDIIVNCAAYTAVDKAEDNVELCDKLNNIAPGYLARAAQANGAAMIQVSTDY
                     VFDGTAHIPYTEEEPTCPASVYGSTKLAGEQNVMDHCEKAMVIRTAWLYSIYGNNFVKT
                     MIRLGQERDSLGVIFDQIGTPTYANDLAQAIFAAINKGVVRGIYHFSDEGVCSWYDFTI
                     AIHRLAGIASCKVKPLHTADYPAKAPRPHYSVLDKTKIKDTFGIEIPHWEESLKRCINQ
                     LRMETL"
     CDS             5718..7292
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MADNTEILRRRTFAIIAHPDAGKTSLTEKLLLFGGQIQVAGAVKS
                     NKIKKTATSDWMEIEKQRGISVTTSVMEFDYRDYKINILDTPGHQDFAEDTYRTLTAVD
                     SVIIVVDGAKGVETQTRKLMEVCRMRNTPVIIFVNKMDREGKDPFDLLDELEEELMIQV
                     RPLSWPIEQGPRFKGVYNIYEQKLDLYQPSKQVVAEKVEIDIHSDELDRQIGDTLADKL
                     RGDLELIEGVYPEFDVETYLQGECAPVFFGSALNNFGVQELLNCFVEIAPAPRPVHAEE
                     REVIPEEPKFTGFIFKITANIDPNHRSCVAFCKICSGKFVRNAPYLHVRHGKTMRFSSP
                     TQFMAQRKTTIDEAWAGDIIGLPDNGTFKIGDTLTEGEQLHFRGLPSFSPEMFKYIENA
                     DPMKQKQLAKGIDQLMDEGVAQLFVNQFNGRKIIGTVGQLQFEVIQYRLLNEYNASCRW
                     EPLSLYKACWIESDDLEELEAFKKRKYQYMAKDREGRDVFLADSNYVLQMAQMDFKNIR
                     FHFTSEF"
     CDS             7588..7731
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MKISAWQSLRKAGCTDRTFILKSNSPVRLFTDLKRGAFILSGCRV
                     KR"
     CDS             7859..9091
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_9"
                     /sec_met_domain="HBT (E-value: 3.4e-18, bitscore: 55.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDEKEITPRTLATLLKVQQMGVHIVLASGR
                     PTYGILPLAKKLELGNYGGYILSYNGAQVINAKNGEVLLERRINPEMLPYLEKKARKNG
                     FAIFTYTEDRMIADQADNEHILQEAFLNRMELIEEPEFSVAVDFAPSKCMLVSDDEEAL
                     IGLEEHWKKRLNGALDVFRSEPYFLEVLPCGIDKSTSLGALLSHLDITPEEIIVIGDGV
                     CDVSMIQFAGLGIAMGNAQDSVKVCADVVTASNEEDGVALAVEKAILSEIRPAEIPLDQ
                     LNERARHALMGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDVFTSTDKLVSS
                     IRVVNSILKKR"
     CDS             9088..10194
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_10"
                     /sec_met_domain="Chorismate_bind (E-value: 1.3e-54,
                     bitscore: 175.2, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLEETNNCEIIDELIRQGRSFAMYRNPGEEEPHFLMQTCGEVHL
                     IRKMEDLNGRTGFVIAPFRVTPQCPIILIRPDCHEIPSCAGNLHTPAQGDDAASYGQQL
                     RSDWSLGAKKAYEACFDVFIRALRERTFDKLVLSRRMTVRREPGFSPAAAFYRACRRYI
                     YSYVYLCYTPQTGVWMGSTPEIILSGEKGEWNTVALAGTQSLQNGELPQQWDEKNREEQ
                     EYVAAYIRKQLRSLGISPTEKGPYPAFAGALSHLKTDFHFSLNDSQRLGDLLKLLHPTP
                     AVCGLPKEEAYRFILDNEGYDRSYYSGFIGWLRPEGRTDLYVNLRCMNVKEDSLTLYAG
                     GGLLASSELDDEFQETEKKMQTMQNLNS"
     CDS             10215..11882
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-08, bitscore:
                     23.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLRAHGVTKVVLCPGSRNAPIVHTLAGHPDFT
                     CYSVTDERSAGFFAIGLALQGGTPAAVCCTSGTALLNLHPAIAEAYYQKVSLVVISADR
                     PAAWINQMDGQTLPQPGVFRSLVKKSVDLPEIHTDEDEWYCNRLLNEALLELNHHGKGP
                     VHINVPVSEPLFQFTAESLPEVRVITRYQGLNVYDRDYDGLIDRLNKYNRRMMIVGQMN
                     LIYLFEKKYSKMLYKQFAWFTEHLGNQTVPGIPIRNFDAALYAMSPEMQEKMIPELVIT
                     YGGHIVSKRMKKYLRQHPPKEHWHVSPDGEVIDLFQGALTTIIEMDPFEFMEKIAFLLD
                     NRTPEYPRQWENFCKELPRPELPYSEMSAIGSLIQALPASCALHLANSSAVRYAQLYSL
                     PDTVEVCCNRGTSGIEGSLSTAIGYAAASKKLNFVVIGDLSFFYDMNALWNNHFGSNLR
                     ILLLNNGGGEIFHTLPGLEMSGTSHRFVTAVHKTSAKGWAEERGFLYQEVQDEKQLDEA
                     MKTFTQPELLTQPVIMEVFTNKNKDARILKDYYHQLKN"
     CDS             11884..12888
                     /locus_tag="ctg27_12"
                     /transl_table=11
                     /translation="MMTKHKMNLFCGMLLLSASLFVEKAQAMFPERYVSEESAARADTI
                     NFRLASAGEAKRLIAAKDSYTANWSPFDIAARLENPEGKREDLVSLAVREVREWTAEEA
                     QQIEQIRKNLNDTIRKYGYRIPFPKEIVLVKTTMKDEGGAGGYTRSNWIALTDATFQRG
                     TEASHTRLLVHETFHILTRLNPGFKKKLYRAIDFNILPKEIEFPEDIRKSRISNPDVSR
                     CDSYATFTIDGKPQNCTMIIYTNRPYTTGKFYQYINVGLIPLDESFKPLRESGKTVIYP
                     LQKATDFFDKVGRNTGYVIDPEEVLADNFAIALLNTPNVHTPELQKKVQELLK"
     CDS             12910..13653
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_13"
                     /sec_met_domain="ECH_1 (E-value: 7.8e-76, bitscore: 244.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTPIKEYEDILFDYYNGIARITINRERYRNAFTPTTTGE
                     MSDALRICREEPDINVVVLTGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMQLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYL"
ORIGIN
        1 ttttataact gttctgatag gactgttttt taatcccatg ccggataaaa aagaaattga
       61 tcggaatgaa ataaagatgg aattgattgc tccggataga ctggaaggaa attatactgt
      121 tagtaaatct attgtggggc agatccaagt atccagtggt attataaaaa aggtgaaaga
      181 tggaacgttt caacttttga taaccggtaa atcttctcct aaagtgtata agttggattt
      241 taattctgat aaaatgatat ttgtttcagg agaactgggt aatggagcaa tccactatga
      301 taaagatttg gataaaatta aaatagtatt taatataaat gaacaaacga catggacaat
      361 ttcaaagtga tttattcgat tccatttttg ttttttatta tcgtgtcctg cagcaactca
      421 tcaactgaga tggttgctaa aagtaagtat gatgctaaga ttgccgagta taaggagttg
      481 aacgaacagc aagcggctgt tattgaagat aatttagaga aaagtaaaat tattaataat
      541 gtggtgacgg aattaaatca gatagccggc aatacacatt ctttgcgtgt gaatgtagag
      601 catggagtgg gggaattgag tcaagcagaa gagatcaatc agaaacttca gactctgaaa
      661 aagcgcttaa gtgcagttga aggtaagcgt agtgacagca gtaagaacct gttggcaacg
      721 atggataaat tgaaaagtat tattgagcaa aaagagattg aaatcaacaa tctcaaacag
      781 gagattgcga accaacaaca gacaatagct aatcagaaaa atacaattgc gagccaacag
      841 gtgacgatcg atgctcagag tcaggagtta atgaataaac aacaggaaat gtggtataaa
      901 ttaggtactg agctacactc tgtcgtagaa gaattaccaa aagtaaaagg aagaaaagat
      961 aagcggaata ttaaaaatac cagatactat attctgaaca aagcaaaaga atgttttgaa
     1021 catgctgcac aactgggaca ttcacttgcc ggttcgaaag cccgacaggt ggaaggggag
     1081 atgagtagat tataaagtgt gattttatag tttttctgtt gttagttaac agaaaacact
     1141 aattttgcat tcgatttaaa ttctattcga atgtcacaac ttccaacatt aatagccgac
     1201 ctcgccctga ttctgatttg tgccggtata atgactctgt tattcaagaa gttgaagcaa
     1261 ccgcttgtgc tgggctatgt ggttgccgga tttcttgcca gtccacatat gccctataca
     1321 ccttcggtga tggatgtagc caatattaaa acctgggctg atattggagt catcttcttg
     1381 ctttttgctc ttggattgga atttagtttt aagaagatag tcaaggtggg aggtacggct
     1441 gttattgccg cctgtaccat tatcttctgt atgattcttc ttgggattgc cgtcgggatg
     1501 gggttcggct ggcaacgtat ggatagcctg ttcttgggag gtatgatcgc catgtcttct
     1561 actacaatta tttataaggc atttgatgac ttaggattgc ggaagaaaca gtttactggt
     1621 ttagtactca gtattcttat tcttgaagat atacttgcca ttgttttaat ggtcatgctt
     1681 tcgacgatgg cagtcagcaa taactttgaa gggacagaaa tgctgggcag tatcggtaag
     1741 ttactttttt tccttattct ttggtttgtc gttggcattt atgccatacc cgagttcctg
     1801 aagcgctgtc ggaaactgat gagtgaagaa acgctgttaa tcgtatcttt ggctctttgt
     1861 ttcggtatgg tggctattgc tgccaatacc ggtttctcgg ctgcttttgg tgctttcatt
     1921 atggggtcta tcctggccga gacaattgag gcggaatcta tcgatcgatt ggtaaagcct
     1981 gtgaaagact tatttggtgc tatctttttt gtatcggtcg ggatgatggt agatcctgcg
     2041 atgattattg aatatgcggt tcctatcata gtcattacgt tggcagtgat tctgggacag
     2101 gcctttttcg gaacaatggg ggttatgttg gcaggacagc ctttaaagac tgccatgcag
     2161 tgtggcttta gcctgacgca gataggggag tttgctttta ttattgcttc tctgggctta
     2221 tcattacatg tgacaagtga tttcctatat ccgattgtag tagctgtttc cgtgatcacg
     2281 acatttctga ccccttatat gattcgtgtt gccgagcctg cctcaaactt cgtcgatcgt
     2341 aagttacccg aatcctggag acgtttcctg atgcgatata ctaccggtac gcggactgtc
     2401 aatcacgaaa gtttgtggcg gaagctattg tttgccttag cacgtattct ggtggtgtat
     2461 tccattgtca gtatttcggt aattaccctt tcgttccgtt ttgtagtacc tttgctacgc
     2521 gaacatttgc cgggtatctg gggcccattg gcaggagctg tttttactat cttgtgcata
     2581 tccccttttt tgcgggccat tatggtgaag aagaatcact cggtcgaatt tataactttg
     2641 tggaatgata atcgtgtcaa tcgcggaccg ctggtttcta cggttgtatt tcgtgtcgca
     2701 gtgtcagttc tgtttgttat gtttgtcatt acccgtttgt ttaaagcttc ggtaggactg
     2761 atgttcggag tggctttgtt actagtgatt ctgatgatac tttcgaggca gttaaaaaaa
     2821 caatccattt tgatagaacg taaatttttt cagaatcttc gttcacgtga tatacgcgct
     2881 gagtatttgg gagagaaaaa accggcttat gccggacgtt tgctttcaag agacctgcat
     2941 ttgactgatt ttgaaatacc gggagagtcg gcttgggccg gaaaaacctt gcttgaactg
     3001 aatctgggta agaagtatgg agtgcatgta gtctccattc ttcggggaaa acgtaggatt
     3061 aacattccgg gtggttctat ccgtctgttt ccgatggaca aaatacaagt gatcggtact
     3121 gatgaccagt tgaatatctt cgccgaagag atgtcgcatg ttgctgtgat cgattcggga
     3181 gtgtttgaga agagtgaaat gactttgaag caattgttga tcgatacaga ctctgctttt
     3241 ctgggcaaaa cgctgcgtga atcgggcatt cgtgataaat accattgcct gattgccggc
     3301 gtggagcggg gaggagaagc tttgatgacg cctgacgtga atgttccttt tgaagaagga
     3361 gatgtagtgt gggtggtagg tgagaatgaa gatgtgtacc ggttaatagg acaaaattgt
     3421 gatagaaaac gttaacaaga tactggcata tcataaaaaa atgcgatatt tgcggaatga
     3481 ttcagataga gactatactt gatatactgg ttaaaggatt cgttatcggc attgtggttt
     3541 ctgcgccgct ggggcctgta ggtgtccttt gtattcagcg tactttgaac aaagggcgtt
     3601 ggtatggatt tgtcaccgga ctgggggctt cgttgagtga tattgcttat gctcttttga
     3661 cgggatatgg catgagcttc gtattcgatt atatcaataa aaatattttt tatctgcaac
     3721 tcctcggaag tatcatgcta ttggcttttg gtatttatac attccgcagc aatcctgtgc
     3781 aatccattcg gcctgtatcg gccaataaag gttcttattt ccacaacttc attaccgcct
     3841 ttgcagttac actttccaat ccgcttatta tttttctttt catcggtctg tttgcccgtt
     3901 ttgcttttgt gcaacccgga gtattggtct ttgaagagat tacgggttat ctggccattg
     3961 ccctcggagc gctggcgtgg tggtttggaa taactttctt tgttaataaa gtgcggacgc
     4021 gattcaattt gcggggtatc tggattttga accgggtgat tggcagtatc gtgatggcag
     4081 tatccgtgtt cggactcata ttcactttgc tgggagaatc tatttattga taggagaaaa
     4141 gacagaagat gaaaatagcg caacaactca aggagaagaa cattgccgaa taccttattt
     4201 atatgtggca gatagaggat ttgatccgtg ccaatgattg tgatgtcgac cggattgagg
     4261 agaatatcgt ttcccgttat caagtgagcg atgaagagcg tcgtgaactg acagaatggt
     4321 atgccaatct ggcttcgatg atgcgggaag agggagttcg tgagaaagga catctccaga
     4381 ttaaccggaa cgtaatcatc aacctgaccg aattgcacgc tgccctgttg gcatcaccta
     4441 aatttccttt ctatagttcg gcttatttca aagcattacc ctttattgta gaattacgaa
     4501 ataaaaacgg tcagaaggaa gaaccggagc tggaaacctg tttcgaagct ttgtatggca
     4561 tgatgctgtt gcgcttgcaa aagaagccgg tcagtccgga gactacgaag gcaatggaag
     4621 ctatcagtag ctttttgtct atgttggcca actattatga taaggataga aaaggagagt
     4681 taaaactgga ataaaacgaa tcagactcac catagagtag tacagggctc catagagatg
     4741 gttttttctt aatatcctat aaacaagaga ttaaaactct gtgagactcc gtgttactct
     4801 gtggtgaatc caactaaaaa aataccgaaa tgaatatatt ggtcaccgga gccaacgggc
     4861 aacttggcaa tgaaatgcag gtacttgcca gagaaaacct gcagtatacg tattttttta
     4921 cggatgtaca ggagttggac atttgtgatg aacaggctgt ttatgcctat gtgagtgaac
     4981 ataagattga catcatcgtg aactgcgctg cttatacagc ggtagacaag gctgaggata
     5041 atgtcgaact ttgcgacaaa ctgaataata tagcaccggg atatctggca cgggcggctc
     5101 aggctaatgg cgctgcaatg attcaagttt ctaccgatta tgtgtttgac ggtacagcgc
     5161 atattcctta tacggaagag gaacctactt gtccggcttc ggtttatggc tctaccaagc
     5221 tggcgggcga acagaacgtg atggatcatt gcgagaaagc tatggtaatt cgtacggcat
     5281 ggttgtactc catctatggc aataattttg taaagacaat gattcgtctc gggcaggagc
     5341 gtgattcttt gggagtcatt ttcgatcaga tcggtacacc gacttatgct aatgatttgg
     5401 cccaggctat ttttgcagcg atcaataaag gcgttgtccg cggcatttac catttcagtg
     5461 acgaaggagt ttgttcctgg tatgacttta ccatagccat ccatcgcctg gcgggcattg
     5521 cttcgtgtaa ggtaaaaccg ttgcataccg ccgattatcc ggcaaaggca ccccgtccac
     5581 actattccgt actcgataaa acaaagataa aagatacatt tggcattgag atcccgcatt
     5641 gggaggagag cctgaaacgt tgcattaatc aattaagaat ggagacactt tgattcttca
     5701 tcctcaattc tcgaaatatg gcagataata cagaaatact aagacggcgc actttcgcca
     5761 ttattgcaca cccggatgcc ggtaaaactt cgttgactga gaagttactg ttgttcggcg
     5821 gacagattca ggtggcagga gcagtaaaaa gtaacaagat caaaaagacg gcaacttccg
     5881 actggatgga gatcgagaaa caacgtggta tctcggtgac aacttcggtg atggagtttg
     5941 actatcggga ctataagatt aatattctgg atactccggg gcaccaggac tttgccgaag
     6001 atacctatcg taccttgacg gcggtagaca gtgtcatcat cgtggtagat ggagcgaagg
     6061 gtgtggaaac ccagacccgc aagctaatgg aagtctgccg gatgcggaat accccggtaa
     6121 tcatctttgt gaacaaaatg gaccgtgaag gtaaagatcc gtttgacttg ctggatgaat
     6181 tggaagaaga actgatgatt caggtacgtc ctctgtcttg gcctatcgaa caaggccccc
     6241 gtttcaaggg agtttataat atctacgaac agaaactgga cctctatcaa ccttccaaac
     6301 aagtggtggc ggagaaagtg gaaatagata ttcattctga cgagttggat cggcagatcg
     6361 gcgatacgct ggcagataag ttacgcggtg atttggaatt gatagaaggt gtatatcccg
     6421 aatttgatgt agaaacatat ctgcagggag agtgtgcacc ggtctttttc ggttcggctt
     6481 taaataattt tggtgtgcag gaactgctca actgttttgt tgagattgcc cccgcccccc
     6541 gtcccgtaca tgcagaagaa cgtgaggtga ttcccgagga gcctaaattt accggtttta
     6601 ttttcaagat tacggctaac atcgacccca atcaccgttc gtgcgtagcc ttctgcaaaa
     6661 tctgttcagg taagtttgta cgaaacgccc cttatctgca tgtacgtcat ggtaagacta
     6721 tgcgtttctc ctcacccacc cagtttatgg cacaacgtaa gacgactatt gacgaggctt
     6781 gggccggaga tattatcggt ttgccggata acggaacatt taagattggc gatacgctta
     6841 ccgaaggaga acaacttcat ttccgtggtt tgccgagctt ctcaccggag atgttcaagt
     6901 acatagagaa tgccgatccg atgaagcaga aacagcttgc caagggcatc gaccagttga
     6961 tggacgaagg tgtggcccag ttgtttgtca atcagttcaa cggtcgcaag attatcggta
     7021 cggtaggtca gttgcagttt gaggttattc aatatcgttt gctgaacgaa tacaatgctt
     7081 cttgccgttg ggagccgttg agtttgtaca aagcatgctg gattgaaagc gatgacctgg
     7141 aagagttgga agcattcaag aaacgtaaat atcagtatat ggccaaggat cgtgaaggac
     7201 gcgatgtttt cctggccgat tcgaactatg tgcttcagat ggcacagatg gatttcaaaa
     7261 atatccggtt ccactttaca agcgaattct gattcgcttc ataaaaaaga ccggatcaag
     7321 acggtggacg agttgcagtg tagtgctatt tgtccaccgt ttgtcgtata tggcattggg
     7381 tcggcgagct ttcccccgat acattccacc ctaacccttt tatcctttaa accaacgttg
     7441 tccgacaccc ccatgtcggg catgctgaca cccccatgtc ggatgtgtcg acacccccat
     7501 gtcggatatc ctttctttaa ggcttagttc cggttggtag gtaagagagg gcatcgatct
     7561 ttctgtccat acaaaaacac cttcttaatg aaaatttcgg cttggcagtc gttgcgaaag
     7621 gctggatgta ctgaccggac ttttatcctt aagagtaaca gcccggtacg tttgtttaca
     7681 gacctgaagc gtggtgcttt cattctgtcc ggttgtcggg tgaaacgatg attcccgcat
     7741 cttctgtgag tccggacgca ggtttctttc tgtaccttat ggtataattt tccctaaaga
     7801 aacagggatg ttgccttaaa tattttacct ttgtaatcta aacaaaaaac tcgaggtcat
     7861 gaagtataaa ctgttagtcc ttgatgtaga cgggacattg ctcaatgatg agaaggagat
     7921 tactcctcgt acccttgcca ctttgttaaa agtacagcag atgggagtac atattgtttt
     7981 ggcctccggt cggcccactt atgggatttt gcctttggca aagaaactgg agctgggtaa
     8041 ctatggcgga tacatcctgt cctataacgg cgcacaggtc attaatgcca aaaatgggga
     8101 agtattgctc gaacggcgta ttaaccccga aatgttgcct tatctggaga agaaagcccg
     8161 taaaaacgga tttgcaatct ttacttacac cgaagaccga atgattgctg atcaggcaga
     8221 taatgaacac attcttcagg aagcattcct caatcggatg gagttgattg aagaacccga
     8281 attttcggtt gccgttgatt ttgctccttc caaatgtatg ttggtcagtg atgacgaaga
     8341 ggcgcttatc ggattggaag aacattggaa aaaacgtttg aacggagcgc tcgatgtatt
     8401 ccggtcggaa ccctatttct tggaagtcct gccatgtggc attgacaaat caacttcgtt
     8461 gggagccttg ctttcccatt tggatatcac tccggaagaa atcattgtta tcggtgatgg
     8521 cgtttgcgat gtttccatga tccagtttgc cggattgggt atcgccatgg gcaatgctca
     8581 ggattcggta aaggtatgtg ccgatgtggt gacggcttcg aatgaagaag acggagttgc
     8641 tcttgccgta gaaaaagcga ttctttctga gattcgtccg gcagagattc ctctcgatca
     8701 attgaacgag cgtgcacgtc atgccttgat gggaaatctg ggcattcaat atacctatgc
     8761 ttccgaagac cgggtagagg ctactatgcc ggtagacgag cggacccgtc agcctttcgg
     8821 cattctgcac ggaggtgcca cgttggcact ggccgagact gttgccggac tgggttcgat
     8881 gattctctgc cagcccgacg agattgtggt tggtatgcag gtcagcggta accacatgtc
     8941 atctgcccac gagggagata ccgtacgtgc cgtcggtacc attatccaca aaggacgttc
     9001 atcacatgtc tggaatgtag acgtatttac gtcgacggac aagttggtgt cttccatacg
     9061 ggtagtgaat agtatattaa agaagagatg acgttagaag aaacaaataa ttgtgagatt
     9121 atagatgaat tgatccgtca gggaaggagc ttcgcaatgt atcgtaatcc gggcgaagag
     9181 gaacctcact ttctgatgca gacttgcgga gaagtacacc ttatccggaa aatggaagat
     9241 ttgaatggtc ggacaggctt tgtcatcgcc cctttccggg tcactccgca atgtcctatc
     9301 atattgatcc ggccggattg tcacgagatt ccttcctgcg ccggaaactt gcatacccct
     9361 gcacaggggg acgatgcggc atcgtacggg caacagctcc gaagcgactg gtcactcggg
     9421 gcgaagaaag cctatgaagc ttgtttcgat gtctttatca gggctttgag ggaacgtact
     9481 tttgataagt tggtactatc ccgcagaatg acggtgagga gagagccggg attctctccc
     9541 gcagcggctt tctaccgggc ttgcaggcgt tacatctatt cgtatgtcta tctttgctat
     9601 actccgcaaa ccggggtgtg gatgggcagt actccggaaa tcattttatc gggtgagaaa
     9661 ggagaatgga atacggtagc gttggcagga acccagtctt tacagaatgg tgagcttccg
     9721 caacaatggg atgaaaagaa ccgggaggag caggagtatg tggcggcata tattcgtaaa
     9781 caactccgct cgttggggat ttctccgacg gagaaaggac cttatccggc ttttgccggg
     9841 gcattgtctc acctgaaaac ggatttccac ttctcgctga acgacagtca gaggttggga
     9901 gatttattga agctgttgca tcccactccc gccgtatgcg gattgccaaa agaagaagct
     9961 taccggttta tccttgacaa tgaaggctat gaccgcagct attattccgg atttataggc
    10021 tggttgaggc cggaagggag aacggacctg tatgtcaact tacgctgtat gaatgtgaaa
    10081 gaagattcgt tgacattgta tgccggaggc ggcctgctgg cctcttccga gttggatgat
    10141 gagtttcagg agacggaaaa gaagatgcag accatgcaga acttgaactc ctaaataaaa
    10201 taatatataa agcgatgtat tcagataaga aaaacatatt gcagttggta gcgttgctcc
    10261 gtgcacatgg ggtgacgaaa gtcgttttat gtcccggaag ccggaatgca ccgattgtac
    10321 atacacttgc cggacatccc gacttcactt gttactcggt aacagacgag cggagtgccg
    10381 gcttttttgc tatcgggctt gctttgcagg gcggaactcc tgccgctgtt tgttgcacat
    10441 cgggcacggc tttgttgaat ttgcatcctg ccatagcaga ggcctactac cagaaagtat
    10501 ctttagtagt tatttccgcc gatcgtcctg ccgcctggat caaccagatg gacggacaga
    10561 ctttacctca gccgggtgtt ttccggtcat tggtgaagaa gtctgtcgat ctgcccgaaa
    10621 tacatacgga cgaggatgaa tggtactgca accgcttgct gaacgaagca ttgcttgaac
    10681 tgaatcatca tggtaaaggc cctgtgcaca tcaacgtgcc ggtttccgaa cccctgttcc
    10741 agtttacggc agagtcactt cccgaagtac gtgtcatcac acgttatcaa ggactgaatg
    10801 tttatgatcg cgactatgac ggcttgatcg accgcctcaa taaatacaac cgccgtatga
    10861 tgatcgtcgg ccagatgaac ctgatttatc tgttcgaaaa gaaatattca aagatgctct
    10921 acaagcagtt tgcctggttc acggagcatt taggcaatca gaccgttccg ggcatcccga
    10981 tccggaactt cgatgcagcc ctctatgcca tgtcacccga gatgcaagag aagatgattc
    11041 ccgaattggt gatcacttac ggggggcata tcgtctctaa acgaatgaaa aagtatcttc
    11101 gccagcatcc gcccaaagag cattggcatg tgtcgccgga tggtgaagtg atcgatctgt
    11161 tccaaggggc attgactacg attatcgaga tggacccatt tgaatttatg gagaagatag
    11221 cttttctgct ggataaccgt acaccggaat atccccggca atgggagaac ttctgcaagg
    11281 agcttccccg accggagttg ccttattccg aaatgtctgc tatcggatca ctcattcagg
    11341 cgttgcctgc ttcgtgtgct ttgcatctgg ccaatagttc cgccgtgcgt tatgcccagc
    11401 tttattcgct tcccgatacg gtagaggttt gttgcaaccg gggtacgagc ggcattgaag
    11461 gttccctttc cacagcgatc ggttatgctg ccgcttcgaa gaagttgaac tttgtggtca
    11521 ttggtgatct gagctttttc tatgatatga atgccctgtg gaacaatcat tttggaagta
    11581 acctccgtat tctgcttttg aataatgggg gaggggagat ttttcatact ttgccgggac
    11641 ttgaaatgtc cggtacttcc catcgctttg tgactgccgt gcataagacg tctgccaagg
    11701 gatgggccga agaacgggga ttcctctatc aggaagtgca ggatgaaaaa cagttggacg
    11761 aagccatgaa aactttcact caacccgagt tactgactca acctgtcatt atggaggttt
    11821 tcaccaataa aaataaagat gcacggatat tgaaagacta ctatcaccaa ctaaaaaact
    11881 aatatgatga ctaagcacaa gatgaaccta ttttgtggga tgctactttt gtcagcttcc
    11941 ctgtttgtgg agaaagctca agccatgttt cccgagagat acgtatcgga ggaatcggca
    12001 gccagggcag atacaatcaa ttttcggttg gcttctgccg gagaagcaaa acgcctgata
    12061 gcggccaaag attcttatac ggctaattgg agtccgtttg acatcgctgc ccgacttgaa
    12121 aatcctgaag gcaaaagaga agacctcgtc agcctggccg ttcgtgaagt gcgtgaatgg
    12181 acagcggaag aagcgcagca gatcgagcag atcaggaaga acctgaatga tacgattcgt
    12241 aaatacggct atcggattcc atttccgaaa gagattgtgc tggtaaagac aacaatgaaa
    12301 gacgaaggag gggcgggagg atacacacgc agtaactgga tcgcattgac ggacgctact
    12361 tttcagcggg ggaccgaagc ttctcacaca cgcctgctgg tgcatgaaac tttccacatc
    12421 ctgacacgtc tcaatcccgg attcaaaaag aaactgtaca gagctatcga cttcaacatc
    12481 ctgcccaaag agattgagtt ccccgaagat atacggaaaa gccgtatctc caatcccgat
    12541 gtcagtcgtt gcgatagtta tgcgactttt accattgacg gtaagccaca gaactgcact
    12601 atgattatct ataccaacag accctatacc acgggtaagt tctatcagta tatcaatgtg
    12661 gggctgattc cgttggacga gtcgttcaag cctctccggg agagtgggaa gacagttatt
    12721 tatccattac agaaagcgac cgacttcttt gataaagtag ggcggaacac cggatatgtc
    12781 atagatccgg aagaggtgct ggcggataat tttgcaattg ctttattgaa cacgcccaat
    12841 gtacatacac ccgaactgca aaagaaagta caggaattac tgaaataata atcatcaaaa
    12901 taaatagaaa tggaaactaa aagagaatgg actcctatta aagaatacga agatattctg
    12961 tttgattact ataacggcat tgcccgtatt acgatcaatc gcgaacgtta ccggaatgct
    13021 ttcaccccta ctacaacagg cgaaatgagc gatgcgctgc gcatctgtcg tgaagagccc
    13081 gatatcaatg ttgtggtatt gaccggtgca ggcgataagg ccttctgttc gggaggcgac
    13141 cagaacgtaa agggccgtgg cggatacatc ggtaaagacg gagtgccccg tctgagtgta
    13201 ctggatgtgc aaaaacaaat ccgttcgatt ccgaaaccgg ttattgctgc cgttaacgga
    13261 tttgccatcg gaggcggaca cgtgttgcat gtcgtatgcg atctctctat tgcttccgaa
    13321 aatgcgatct tcggacagac aggtcctcgt gtaggtagtt tcgatgccgg cttcggatca
    13381 tcttatcttg cccgcgttgt gggacagaag aaggcccgtg agatctggtt cctttgtcgc
    13441 aagtataatg cgcaggaggc tctggatatg gggctggtca ataaagtggt accgctggat
    13501 aaactggaag acgagtatgt tcagtgggcg gaggagatga tgcagcttag tccgttggca
    13561 ctccgcatga ttaaagccgg tctgaatgcc gaactcgacg gtcaagccgg tattcaggaa
    13621 ctggcaggtg atgccactct gctttattac ctta
//
