LOCUS       c00140_gnlPro..        14778 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNIFJDFK_140.
ACCESSION   c00140_gnlPro..
VERSION     c00140_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:36:25
            Original ID  :: gnl|Prokka|CNIFJDFK_140
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14778
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..78
                     /locus_tag="ctg140_1"
                     /transl_table=11
                     /translation="TMLFTKIAEININIYSIVVKLKIEN"
     protocluster    1..14778
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[146:4778]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      147..4778
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14778
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14778
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(147..734)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.7e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIAIINKLRTEN"
     CDS             complement(749..1465)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_3"
                     /sec_met_domain="FMN_bind (E-value: 4.5e-23, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             complement(1492..2484)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.4e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(2490..3827)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_5"
                     /sec_met_domain="Fer4_10 (E-value: 2e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.2e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.5e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 7.5e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(3852..4778)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     5.8e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.9e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 9.6e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.6e-08, bitscore: 25.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.3e-06, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKPAAVSKEAVETPAEKATEAPKVTE"
     CDS             complement(4786..5211)
                     /locus_tag="ctg140_7"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVLLAFVLPFVLLIFSLFLLMALIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             complement(5583..5723)
                     /locus_tag="ctg140_8"
                     /transl_table=11
                     /translation="MKKKTVCCSDLGAYINELLKRAKLKNEYVCETLGMGHDVLNGIKK
                     G"
     CDS             5894..6517
                     /locus_tag="ctg140_9"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFTRRSCKDFVSPSHLVIVDVDGLH
                     SYQEAVEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCHYSSTTNDTKNITENMSWAMR
                     YVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTK"
     CDS             6556..8397
                     /locus_tag="ctg140_10"
                     /transl_table=11
                     /translation="MTDIESLCRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPPHTGAYNKVGNDNISEEREGEEELLPGSEPQHQLPTFPKNNWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVTIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKTHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGREMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPADNRKDDIITRWDVSISQ
                     EDFHAVLSLAEPLYCHATHILSFLPSTEVSHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKHGKLISMDGKGLYARACVYE"
     CDS             complement(8579..8797)
                     /locus_tag="ctg140_11"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             9017..9505
                     /locus_tag="ctg140_12"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             9682..9789
                     /locus_tag="ctg140_13"
                     /transl_table=11
                     /translation="MSKSSSSRSVWSLVLKIIITVATAIGGVFGIQSCM"
     CDS             9794..10216
                     /locus_tag="ctg140_14"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRGRALEKIGAHCRNHNAHSVGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALVVGHRDLNPMKGCPCFDAVNEYAEIASF"
     CDS             complement(10490..10936)
                     /locus_tag="ctg140_15"
                     /transl_table=11
                     /translation="MYSMEINKQLLEVLFVEAKESPRLRQNFDLRTSPNDTSQRMLNAL
                     LPGTVVPIHQHENTTETVICLCGKLDEVIYEEVILYENGVEELTQGMDAQDVARKVEYR
                     EVQRIHLNPTETKYGCQVPKGVWHTVEVIEPSVIFEAKDGAYVR"
     CDS             complement(11028..11705)
                     /locus_tag="ctg140_16"
                     /transl_table=11
                     /translation="MKYLLVVAHPDDEVLGAGASMWRWSHNGNTVDVAIMCTEAKARAF
                     RPEDKELDDDLNASAGFLGIHKKYEATFPNIEMNTVPHLKLVQFIEKAIRESEPDIIIT
                     HHPADTNNDHLQTSMACQEAIRLFQRQPSVKPVKEFWYMEVPSCSEWAINDAMNLFRPN
                     CYVEVGMEGVKAKCKALAMYRGVMRPYPHPRSNEYIEGLAAMRGSQWGCKYAEAFQVVL
                     RRY"
     CDS             complement(12181..12444)
                     /locus_tag="ctg140_17"
                     /transl_table=11
                     /translation="MYRHGEQQTEDADCEAVNSESCRDVIILKPDSLPDTSLRLVRMWS
                     RKSTTSSAVYSATTLRYVGFPSSSSITVVAALGRRSRNALRM"
     CDS             complement(12448..13311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg140_18"
                     /sec_met_domain="Epimerase (E-value: 9.7e-16, bitscore:
                     48.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVLIIGDDSYIGIKIKAWLDIFSTEYKTGIVSSRDGRWKTEAD
                     FSQYETVVNLAGLAHINNITEEMRPKFYAINCDLPITLGKWAKEHGVKHFIHFSSMNVY
                     GDFCDDLKSRDCEKPTSFYGDSKYQGDLGLRELEDKTFKVSYVRPPFVYGKGCKGNYNT
                     VVKLALKVPFFPNYPNKKSMIYIDNLCEFIRMVIDTELDGVLTPQNKELVSTCDLIQAI
                     AMAHGRVLHTPSIFNPIIWIAVKMTRKIRRGLGNDNYTQKLSDYFNYQYCVVSFRDSVE
                     QTENDK"
     CDS             complement(13320..14465)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg140_19"
                     /sec_met_domain="CPSase_L_D2 (E-value: 3.4e-07, bitscore:
                     20.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNSYNGHLCIVFALEHYNPLNMIRAFGENGINPVYISVKRRYET
                     ACLSKYISKLHRVGLVEEGYELLMNTYGNVAVETGKKPYIVFSDDKSVGYFDLHYDEWK
                     DKFITYNAGRAGRINEFMDKYEIQQLAKKHGFNVLDSYVISKEDPLPEGLWYPIITKDI
                     SPNSGNWKNDVFVCWNEQELKDAIKQIASPLIMIQHFVDKQNEMALEGYTINHGKDIQI
                     ITQMKWKYLIQGYYSPYHDVCMFEDKEMEEKLQAMFEEIGYEGIFEVEFLIDKDGTYYF
                     METNFRASAWNPTCKFAGMPLDYLWVKGMENGYIAPADRKEFEPFTSMSEVIDFGKRVD
                     GGMVSLAEWLRDFKDAKCVYIYDKEDRAPWDAVIKNWEQFK"
ORIGIN
        1 acgatgttgt ttacaaagat tgccgagata aatatcaata tatattccat agttgttaaa
       61 ttgaaaattg agaattaaaa attaaaaaat cagagaatgt gaaaatgaaa ttaagaatat
      121 ggttcatatc tattatttct caattctcaa ttttcagttc tcaatttatt aattattgca
      181 atgaggtatc ccaaagcgat gaaagcaccc ggagccaata cgaataccaa cattccatat
      241 tcttccggca tgatggtcaa atcgaagatt ttaccggttc ccaaaaactc gcggacagca
      301 cccagtaaag tcagggcgat ggtaaagcca agccccatac cgataccgtc gaacatagaa
      361 gcaactgcgt tattcttggc agcgaaggct tcggcacgtc ccagtacaat acagttcact
      421 acaatcaacg gaatgaaaag accgagtgta gcatacagtc ccggcacgta agcctgcatc
      481 accatttgaa gcaaggtcac gaaggatgcg atcaccacaa taaacgatgg gatacgcacc
      541 atgtccggaa tcaggttctt tattaaagaa atcaccacat tcgagcagat caatacgaac
      601 atggtagcca gtcccatacc cataccattg atagccgatg atgtagtacc caatgtagga
      661 cacataccaa gcaggagtac aaacgtagga ttctctttga taatcccgtt catcattact
      721 ttaaagttat tcatatctgt ctcctttctt atttagcact gactgaatca gttagttcaa
      781 ctttgatcgt agctcccgta gcagcgtcag cagcatctgc gtccgcgcct ttcgcttttt
      841 gagaagcacc ggttacacca ttcacttccc cgccttcggc cttataggcc tgataagcag
      901 cattcacggc attcaagaaa gcgcgtgaag taatggtaga agctgtgatg gcatccactg
      961 ctcccccatc tttactgacg gtcaacggag cttcacccgg attcataccc aaaatagatt
     1021 tcgtactctc ttcgtgagat actgcctttt ctcctttcgc gggatcatac gctccgaacc
     1081 atttgtcggc tttagagccc aatcccggag tttccgtgtg agccaacaga gagtagttat
     1141 agattttccc ttcggcatta aagcctacca gcactttcag ttcaccgcca aatcccattg
     1201 atttagcttc aacagccgta cctacaagct cttcaccgtt cttagccgga taaacgataa
     1261 agtcaacatt cttctttcca tctttctcac tgaagatcgt atcgctttcc gctaccggat
     1321 tattggtaaa ttcgggaaga acctttttca aggcctcgtt cagtgtcttc gcgttcgctt
     1381 cggcaatggg gccttttgtc agttcattta cataagccag caacgcaacg gaaatagcag
     1441 tcactcccgt aagtaccagc aacatattct ttaaagatga ttctaacttt ttcatttctt
     1501 cttcgctacc tccccaaagc gttttggttt acaataggtg ttaatcagcg gagtgaacgc
     1561 attcataatc aggatggcga acgacatacc ttcgggatag gcgccgaaca gacggataac
     1621 taccgtcagc agaccgatac atacaccata gatcagcatc cctttcttac tcatcggaga
     1681 agtcacatag tcggttgcca taaagacagc acccagcatc agaccaccgg aaagcaactg
     1741 caataccgga gaaacgtatt tttccggatc tgccaggtgc atgatgcctg caaagacaaa
     1801 cacagtagcc aggatagaca caggaatatg ccaggtgatg attttcttcc agagcatata
     1861 aacgagtccg atcagcagag ccagtgcact cacttcaccc aagcatccgc cattctgtcc
     1921 gatcaacaag gtcaatgcgt ccggaatctg gcttaaagcg gcagtgtcac cgtaaatggc
     1981 ttgcttcatc aaggccagcg gagtggcacc ggtggtagca tccgtataag cggtcaactg
     2041 tccgactacc ggccagctgg tcatctgcac cgggaaagaa agcagcagga atacgcggcc
     2101 tgccaatgcc gggttgaaag gattgcagcc taatccgccg aaagacattt tgcctacacc
     2161 gatagcaaac agtgcaccga ggatgataat ccagataggc aagttagacg gtaaattaaa
     2221 tgccaacaac acacctgtga tgatggcaga gccgtcgcag atggtggtgg tcggtttctt
     2281 cattaaatat tttccgatcg cccattcgaa gaacaaacaa gccgcaacgg aagtagccgt
     2341 gacaatcagg gcacccagtc cgaagaaata gagagacacc agaaaagccg gaatcagtgc
     2401 aatcagcacg ccatacatat ttttctgtac gctgtctccg ccatgaacgt ggggcgatag
     2461 tgatacgatt aatttatttt ccatattcgt tattttttag cttgacgtgc acgaatcata
     2521 gctcccactt tgcctttacc cagacgacaa tagtcgagca gcggacggtt ggcaggacaa
     2581 gtgaactggc aagagccgca ctcgatacaa tccatgattc tttctttttc cattgtttca
     2641 aaatctccgt tttcagacaa ggctccgagc aagtacggtt ccagtcccat cggacaggca
     2701 ctcacgcact tcgcgcaacg gatgcaggtt tgagcttcac cacgtttggc ttccttccgg
     2761 ttcataatca ggatgccgga actgcccttc gcagtaggaa cctcgatatt taccaacgcc
     2821 ttacccatca tcggaccgcc accgatcacc ttacccgtat cttcgggcag accaccgcaa
     2881 gcgtcaatca actgtttcat cggtgtaccg atacgggcca ggaaattaga cggcttcgca
     2941 accgactttc ccgtcacggt aatcacccgt tcaaacaacg gtttattctt ctgcacagct
     3001 tcataaacgg caaacgccgt tcccacgttc tgcacgactg ctcccgtaga gataggcaac
     3061 gcaccgctcg ccacctgacg tttggtgatc gcatcgatca gctgcttttc acctccttgc
     3121 ggatatttca ccttcaaggg aacgacttcg atgcctgcat agctggaagc tactttagtc
     3181 atcagttcga tagcatcggg cttattattt tcgattccga taaatgcctt attcactttc
     3241 accgctttca tcaggatgga aacacctacc atgatttctt ccgcgtgttc cagcatcagc
     3301 tgatggtcgg cagtcaaata aggttcacat tctacggcat tgataatcac acattcagct
     3361 ttaaaagaag gaggaggaca aagtttcacc tgtgtaggga aacaagcacc acccagacca
     3421 acgattccgg catcggcaat tttcttcacg atctcttctg cggaaagctc acattccttc
     3481 accagtgtgg cgctacggtc gattgtttct tcccattcgt cgccttccac atcgataaag
     3541 atagcaggtt tcgcataacc gctggcatcg acaatagtat caatcttcgc cactttacca
     3601 ctgaccgaag agtgaattgc tgccgaaaca aagccggcag gttcagcaat tttagtgcct
     3661 acctttacca catccccttt cgctacaacc ggttttgcag gcgcaccaat gtgctgcccc
     3721 agcaaaataa cagcctttgc aggaacttcc gctgtgataa taggttgatg tgccgacaat
     3781 ttattttcgt gtggatgaac tccaccaatt gaaaatgtct ttaacataca gttctgtatt
     3841 ttattctgtt attattctgt tactttcgga gcttctgtag ccttttcagc aggagtttcc
     3901 accgcttctt tagaaacagc agccggtttt ggagcagccg gagcttcttc tttcggtttc
     3961 ctcggcggga aattcaattc gataatggta ttctgcggac agacttccac acatttccgg
     4021 caagatttgc acttgtgcgg atcgatgtaa gccaagttgt tctccaacgt gatagcttcg
     4081 aacggacaag tcttcacgca tttgccacag ccgatacaac tcaccgtaca agccttgcgt
     4141 gccacagctc ccttgtcttt attcacacaa gagatataca cacggcgtga tttctttcct
     4201 tgcggacgga tttcgatgat cgccttcgga caagccttca cacaggcacc gcaagcggta
     4261 catttcgctt catccacttc cggaagtcct gtttcaggat tcatgtggat ggcatcgaac
     4321 tggcaggcag ccacacagtc accacacccc agacatccgt aactacaacc cgtttcccca
     4381 ccatagagcg aagcggcaat agcgcaactc ttcgcaccgt cgtactgatt aatacgcgga
     4441 cgattcatac acgttccgtt acatcttacc actgctacca tcggttcagc ttctccggct
     4501 gcaagcccta ggatatcagc aatttgtgcc atgacaggct gtccgcctac ggggcagaat
     4561 ttaccatcca gcgaaccggc tttgacgcaa gcgtcggcaa agccgctaca accgggatag
     4621 ccacatccac cacaattagc ctggggaagc acttctccca cctgggcaat ccgcgggtct
     4681 tcatacacgg caaatttctt ggaagccaca taaagaatag cggccagcac gagcgctata
     4741 gctcccaatg aaatcactgc aatcagaatc aaattcataa tgtttttagt tatttattgg
     4801 ttttatagta aatgaaaatt gttgtttgag tcgcgttttg ttaagccata aaacgaaata
     4861 ataaggtata aggacagcca gagaaagaag agctgcatac agttcattct ctatcaatgc
     4921 catcaaaaga aacaacgaaa atataagaag tacgaaagga agtacgaaag ctaacaatac
     4981 cgccatcatg cccatcgacg tttcgccgac caccatcacc ttctctccca cctgatagga
     5041 agaagctgcg gtatctatga tatctatgat tttgtcctta ctatccgccg aggaacaatg
     5101 cccctttgcg ctacatgccg cacaagccga tgtctggaca atcctcaccg acagatgaga
     5161 accctgtatg ttttccacaa tacctagatg ctttatagta ttattcgtca ttttgcaaac
     5221 tccgcattac aaatcgcggc aaatttaatc attatttgtg aactacgaag cattcctcaa
     5281 actttttcta cctaataaaa tgttattttt tgtgttctcg ttatcgcaca cggaaaaggt
     5341 atggctacca tttgatattt cccaagaatg acaaatagac atcctaaaca aaaaaatccc
     5401 ggccttttta tttattcagc cgggattttc tatcaattat ttcacggatt actccactat
     5461 cctcttcttg tagtagcgca gatacattct caccaacgta ttcaaaatca gttcaatctc
     5521 ctcttcgttg taggcattca aacagagatc cattactttt atataatcgt tcaatgggag
     5581 atttagccct tttttatgcc attcaaaaca tcatgtccca tacccagggt ctcgcataca
     5641 tactcatttt tcaatttcgc acgtttaagc aactcattaa tataagctcc caaatcactg
     5701 caacaaaccg ttttcttttt catctttgtt ttttgttgtt aaatacacac tttaataatt
     5761 aattatttta acttttatcc tcacatatca gggtagagtc tattttgtta ttactacctt
     5821 catgccgtgt ttttgaaaca cactcatatt ttttgcaaaa ataaacattt taacttataa
     5881 caaaaagaaa atgatgtcaa acaactacag aatgtcctat tttatgccac ctatcgctcc
     5941 catcaaagac aaacaaggcc gactgatgac tcctcccacg cttatcccct tctgcgaagt
     6001 ctccatcgaa caagttttcc aaatgattac ttgcaatgag aatctcaaaa ccctgaccgc
     6061 acaagtacgg aatgccacag atatacgagc cgccaaagca tcattgcttc cgtatgtgac
     6121 cccttgcggc acattcaccc gccgtagctg taaggatttc gtctccccgt ctcatctggt
     6181 gatagtagat gtggacggtc tccactctta tcaggaagca gtagaaatgc gacgtatgct
     6241 ctatgacgat cctctcctac aacctgtact cacctttatc agccccagcg gactgggtgt
     6301 aaaggcattt gttccttgcc attattcctc cacgacaaat gatacaaaaa atatcacaga
     6361 aaacatgagt tgggcgatgc ggtacgtaga gacggcatac aatacggtaa cagcggtttc
     6421 ttccgaaacg aaatccaaag tagatttctc cggcaaagac ctcgtgagat cctgtttcct
     6481 tagttacgac ccagaagcat tgttcagaac caagtaaacg agaataatta aacattattt
     6541 tataaaaatc aaaacatgac cgatattgaa tctttatgcc gtctcaccga agcagtcgaa
     6601 gcggcaggag cggacattgc tcccacttat cttgaatacg tacaattgtc attcgccatc
     6661 gcaacggatt gcggtgaagc aggacgtgac ttttttcatc gcctgtgccg ggtgtctccc
     6721 aagtatcagc gcgaacatgc cgaacgggta ttctccaacg cactccacac ccaacgtgga
     6781 gaagtgcact tgggcaccgc tttccacctg gccgaagcga cgggagtaag catctgcata
     6841 gaagaaatgc ccaaacatcc cacaggtaca aaaggtacag caggtacagc acgcaaattt
     6901 cccccacaca cgggcgcgta taataaggta gggaatgaca atatctccga agaaagagaa
     6961 ggggaagaag aactattgcc gggcagtgaa ccgcaacatc aattgcccac ttttccgaaa
     7021 aacaactggc cggaattctt gcaacgtatc ataaaagccg ggagcagccc aatacaacac
     7081 gacatcatgt tattgggagc gctcactgcc ctgggtgctt gtatgtcgcg ccacgtgcga
     7141 tgcctatatg gcggcaaata ccatcacccc agcctccaat gtttcgtagt ggctccttcg
     7201 gcttccggca aaggtatcct ttcctacatc cgcttactcg tggaacctat ccacgacgag
     7261 atccgcaaag aagtgaccat acagatgaaa gcatacaaaa aagagaaagc cgagtacgat
     7321 gcaatgggaa aagaacgaac caaaaaggag gctccacaaa tgccccctaa caggatgttc
     7381 ctcatttcgg gcaacaacac cggtacgggt atcctacaaa acatcatgga ctccgacgga
     7441 accggactta tctgcgaagc ggaagcggac accctttcca ccgccatcgg atcggatcac
     7501 ggtcattgga gcgataccct gcgcaaagcg ttcgaccacg accgcttgtc ctacaaccgc
     7561 cgcaccgacc aggaataccg ggaagtgaag aaaagctatc tttccgtcct gatttcgggt
     7621 acgccgtcgc aggtgcaaac tttcattccg acagcagaag acggatcata ctcccgccaa
     7681 ttatattatt acatgtgcgg aatcagtaaa tggatcagcc aatttatgga caacgagata
     7741 gattgggagg agatattcac cgctatggga ctggaatgga aagaaaagtt gagcgtgata
     7801 aaaactcacg gcattcatac cctgcaactc acggatgaac aaaaagaaga aatcgacacc
     7861 gtcttttccg acttgtttga acgctccagt gtagctaatg gaagggaaat gtatagtttt
     7921 gtggcacgtc tggccgtcaa tctatgcaga atcatgtcgg aagtagccgt attgcgtgcc
     7981 ctcgaaagcc cgcagcccta cgacttcaag acctctccca cctctccttt cacaccggac
     8041 aaggagattc ctgcggacaa ccgcaaagat gacatcatca ctcgttggga tgtatccatt
     8101 tcacaggaag actttcatgc tgtgcttagt cttgcggaac ctctctactg tcatgccacg
     8161 catattctat cgttcctccc cagtacagaa gtcagccatc gtcctaatgc cgatcgtgat
     8221 tatcttttcc agaaactggg tgatgaattt actcgtaccc agttactgga agaagcagtt
     8281 gccatgggaa ttaaagaaaa cacagccctc acttggctga aacggctcac caaacacgga
     8341 aaattaatca gtatggacgg taaagggttg tatgcgcgtg cgtgtgtgta tgagtgaacc
     8401 ggaaaaagtg tacctactgt acccgtttta cttacggata cggtagtcat ttcaattacc
     8461 gcatccgttt tgactgatac aatcgttttt ctttcataaa gcatcgcttt aggaggtgta
     8521 aagctaagct ttagacatcg taaagcggtg ctttatacac cataaagcga cgctttattt
     8581 aaggctctcc taaagcatcc acaatgactc tcacctccaa cggtgtgaat gagcgtcgct
     8641 ttgattcgta gcctaagtcg tacaggcgtt gcagaagtcc gggacacaaa gagatccatt
     8701 tcttcatttt tcgataggca gcgatgtcag ttagttgtgg agaatagagt tgcgccagtt
     8761 ccatgcgccc gtaagcacgt attttaaatt cactcatgat ggatatattt ctgatttact
     8821 gttacaaaaa taacaaaaaa cgactatata accaacgttt ttccattgaa taaccgacta
     8881 taatgacaaa taaccgaccg ctaccagaca caaccgtgca cagctgattt ccgggagatc
     8941 cggagtagta tttttgtatc gtcgaaaggg aaaagaagcc ccggacaata tgtttaaccc
     9001 tttaatttat tgttttatga ttcgttacaa aatttatcag aaccagcaga agaaaggctt
     9061 gaatgcgggt aagtggttcg cccgtgcagt aagcgacgag acgtttgatt tggcaaagct
     9121 tgccgaacat atgtcgaagc acaattcacc gtattccggt ggtgtcatca aaggtgtgct
     9181 ttcggatatg gtagattgca tcaaggaatt gttgctagac ggcaagtgtg tgaaaattga
     9241 tgatcttgcc atttttggtg tgggtattcg tagtaaggca gccgatacgc tggaagagtt
     9301 ctcgttggag aagaatatta gcggcatgcg tttgaaagcc cgtgccaccg gtaatctgtc
     9361 gaccaataat ctgaaactcg acagccagtt gaagcagcag gcggaatatc agaaaccgac
     9421 aactgccgga ggaggttctg attcgggtga caaccctgat ccgaaaccgg atggaggtgg
     9481 cgaagcgcct gacccggctg cctaaaagat tcaccacaga ctacacagat ttccacagat
     9541 tatattgaat tggtagttgt taaagtagtc gattatttat ctgtgtgagt ctgtgtagat
     9601 ctgtgctaaa tccatggcaa acctacggta aatctgtggt aaaagaaaac tattattaat
     9661 ttatttaaaa cctgttattg tatgagtaaa tcatcatctt cccgctcagt atggagctta
     9721 gttctcaaaa tcattatcac tgtagccacc gccatcggag gtgtgttcgg aatacaaagt
     9781 tgcatgtaac cccatgcgga ctattacatt aattatcatt cattgcagtg ccacgccgga
     9841 aggaaagtcc ctttcggcgg aggcttgccg acaggatcat atcttgcacc gtggtttccg
     9901 tgatattggc tatcattttt acattactcg tgatggggag atccaccggg gacgtgcgtt
     9961 agaaaaaatc ggggcacact gccgtaatca taatgcccat tcggttggtg tttgttatga
    10021 gggagggctg gatgcgaacg gaaaaccgaa agatacgcgt acactggaac aaaaaggagc
    10081 tttgcttgct ttgttgaggg agttgaaaag gcagtttccg aaagcactgg tcgtgggaca
    10141 ccgggactta aatccgatga aaggatgtcc gtgttttgat gcggtgaatg aatatgcaga
    10201 aatagcatcc ttttaggttt ccaccactag cttattgtat aaaaaatatc aacgatcttc
    10261 acagacagtt ggtatttttg gaaatcatat tagtgttaac actaatatga agagcgagat
    10321 taggacaata ccactatatt gctcctaatc tactaaatgt agggattcat gtttgtcaca
    10381 tgaatctagg gacctacatt tttccatttc actgtaaatg ttcaatttta acataacgta
    10441 ttgaaagtac tttcagtact tcctattcat ttcatctgtt tttcatcgtt taacgaacat
    10501 aagctccatc tttagcctca aaaatgacag atggttcaat cacttccaca gtatgccata
    10561 ccccctttgg tacctgacaa ccatatttgg tttctgtggg attgagatgg atacgctgta
    10621 cttctcgata ctcaacctta cgagctacat cttgagcgtc cataccttgt gtaagttcct
    10681 ccacaccatt ctcatacaga attacttcct catagattac ttcgtccaac ttaccacaca
    10741 ggcagattac tgtttcggta gtattctcat gttgatgaat agggacaact gtacctggaa
    10801 gtaaagcatt gagcattctc tggctcgtgt catttggtga agtgcgtaaa tcgaagtttt
    10861 ggcgtaaacg tgggctctct ttagcctcta caaagagaac ttcaagcaat tgtttattta
    10921 tttccatact atacattcaa ttattgagca tcctctttgc tcttctagga acaaagaggt
    10981 aaaagcaaaa tgcccataga cctttcataa actccataaa ctacacatta atatcttctc
    11041 aatacaactt gaaatgcttc agcatactta catccccatt gactgcctcg cattgctgct
    11101 aatccctcaa tatattcatt gctacgagga tgagggtaag gccgcataac accacggtac
    11161 attgccaacg ccttgcactt tgctttcacg ccttccatac ccacctcaac ataacagtta
    11221 ggacggaata aattcatggc atcattgata gcccattcac tacatgaagg aacttccata
    11281 taccaaaatt ctttcactgg cttcacactt ggctgacgtt ggaacaaacg gatagcctcc
    11341 tgacaagcca ttgaagtctg caaatgatca ttgttggtat cagctggatg atgagtaata
    11401 ataatatctg gttcactttc acggattgct ttctcaatga actgcaccag cttcaaatga
    11461 ggcacagtat tcatctcaat atttgggaag gttgcctcat acttcttatg tatacccaag
    11521 aaaccagcag atgcattcaa gtcatcatcc aattccttgt cttcgggacg aaatgcacga
    11581 gcctttgcct ccgtacacat tattgccacg tcaaccgtat tgccattatg cgaccacctc
    11641 cacatggatg cacctgcccc gagaacttcg tcatcgggat gtgctactac taataaatat
    11701 ttcattgcat ttgtctttat ttgtaagcag tcactttaga cccgttacaa gcctaaagca
    11761 tttattttta tagttattta acatattgtt tacttatcga ctttatacaa tagcaaccag
    11821 tagctgccat ttatggggga aggagatata caagttcatc cgtattcttt atccgacgga
    11881 agacgtcgca cagatactgt tgtagattga gtttatgatt gcagatgttg acaaacaccg
    11941 attacaggca ggcaaaacac ctttccactt ccgggtccca gtaacgcctc tttatctccc
    12001 taccctcgta gaaaagcatg tctacgatcc agataatcct ccctgcacca ttcgatacct
    12061 gcctaagttt atacaacgac cttcgcatgt ggagcagaca gaccacacgg acaatcagct
    12121 cgcacacgtc atagcactta tacagtgata ccccatcagg ataaaggtat atcttgcgcg
    12181 tcacatcctc aaggcatttc tgctccgcct ccctagtgca gcgaccacgg ttatggaaga
    12241 cgaactgggg aaacctacgt aacggagagt agtggcagaa tatacagcgc ttgaagtagt
    12301 gctctttcgg ctccacatcc tcaccaatct caatgatgta tcaggcagag aatccggttt
    12361 caggattatc acatccctac aggattcgga attcaccgcc tcacagtccg catcctcggt
    12421 ctgctgctcc ccatgacgat acattcttta tttatcattt tctgtttgtt caacagaatc
    12481 tctgaaacta accacacaat attgataatt aaagtagtcc gagagtttct gggtgtagtt
    12541 gtcgtttccc aatcctctgc gaatctttcg cgtcatcttc acggcaatcc agatgatagg
    12601 attgaatata gaaggagtgt gtaataccct gccgtgagcc attgctattg cttgaatcaa
    12661 gtcacaagtc gagaccaact ctttattctg cggagtcaac acaccatcaa gctctgtgtc
    12721 aatcaccatg cggatgaatt cgcagaggtt gtcgatataa atcatgctct tcttgttcgg
    12781 ataatttgga aagaatggaa ctttcaacgc aagctttact acggtgttat aattgccttt
    12841 acaaccttta ccataaacaa acggaggacg gacataagac actttgaacg ttttatcttc
    12901 aagttctcgc aatcccaagt caccttgata cttgctatcg ccatagaaac tggttggttt
    12961 ctcacagtca cgactcttca ggtcatcaca gaaatcaccg taaacattca tcgaactgaa
    13021 gtgaataaag tgcttcacac catgttcctt cgcccatttg ccgagagtaa tcggcaggtc
    13081 gcagttgatg gcatagaact tcggacgcat ctcttcggtt atattgttga tgtgagccaa
    13141 acctgccaga ttcactacag tctcgtactg gctgaaatcc gcttctgtct tccagcgacc
    13201 atctcttgaa gacacaatac cagtcttata ctccgtagaa aagatgtcga gccaagcctt
    13261 tatcttgatt ccaatatagc tatcgtcgcc gattatcaga actcttctca ttttgaaaac
    13321 tacttaaatt gctcccaatt ttttatcacc gcatcccatg gggcacgatc ttctttatca
    13381 taaatataca cgcactttgc atccttgaag tcgcgtagcc attctgccaa gctcaccatt
    13441 ccaccatcaa ctcgcttgcc aaagtcaatc acttcgctca ttgaggtgaa cggctcaaac
    13501 tctttcctgt cagcaggggc gatgtagcca ttctccatgc ctttcaccca gagatagtct
    13561 agcggcattc cagcaaactt acaggtcgga ttccaggccg aagcacggaa gttggtttcc
    13621 ataaaatagt acgttccgtc cttatctatc aggaactcca cctcaaatat tccttcatag
    13681 ccaatctcct caaacatcgc ttgcaacttc tcctccatct ccttatcctc gaacatacac
    13741 acatcatggt aaggcgaata gtaaccctga atcagatact tccatttcat ctgggtgata
    13801 atctgtatat cctttccatg attaattgta tatccttcca aagccatctc attttgcttg
    13861 tccacaaagt gttgaatcat aatcaacgga cttgctattt gcttgatggc atccttcaac
    13921 tcctgttcgt tccagcaaac aaaaacgtcg ttcttccagt tgcctgagtt tggcgaaata
    13981 tccttcgtga taattggata ccacagacct tccggcaacg ggtcttcctt gctaatcacg
    14041 taactatcca gcacattaaa tccatgcttc tttgccaact gctgaatctc gtacttatcc
    14101 atgaactcat tgatgcgacc agctcggccg gcattgtaag taatgaactt gtccttccac
    14161 tcgtcgtaat gcaagtcaaa gtatcccacc gatttgtcat ctgagaacac aatgtacggt
    14221 tttttgcccg tctcgacagc cacattgcca tacgtgttca tcagcaattc atatccctcc
    14281 tctaccaagc caacacggtg aagttttgag atatacttac tgaggcaagc cgtctcgtaa
    14341 cgacgtttca ccgaaatata cactggattg ataccattct caccgaaggc acgaatcata
    14401 ttcagcggat tgtaatgctc caaggcaaat acaatgcata gatgtccatt ataactgtta
    14461 ttcattgttc ttcttgtatt tactttcgtc tttataaaca ccgtcacctg tcaagaccac
    14521 tttgattata ccaaagaaaa tcttgacatc gagccacagg ctctgctgct ctacatagtc
    14581 agcatcaaac tccatctgca aatcacgctc tgcagcacgg tcatacacat cgatggtgca
    14641 gaacatgcca ggagccacat catatcgctt gaggaagcga gcatcatcct tgtatggctc
    14701 aaactcaaaa tccaaaattg gtctcggtcc gattatcgcc atctgtccaa taatgacgtt
    14761 gaacatctgt ggcaattc
//
