LOCUS       c00004_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEEPFOLP_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:12:41
            Original ID  :: gnl|Prokka|OEEPFOLP_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 127454
            Orig. end    :: 150682
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[137454:140682]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             347..562
                     /locus_tag="ctg4_112"
                     /transl_table=11
                     /translation="MITYKLNHTPEDGFNTFGISAFCGKKLIKSVSGISESFREMTELV
                     EMCNELELELCQLDDIIEDYLTDFTL"
     CDS             653..1531
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_113"
                     /sec_met_domain="Radical_SAM (E-value: 6.7e-13, bitscore:
                     43.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MICNLCPRKCGAVRTAHSGNGFCKMGELPVVARVAPHYGEEPCIS
                     GTKGSGTVFFSGCTMRCVYCQNYEISNEDGGRTITPERLAECYKELEDKGVHNINLVTA
                     DHFAHAVVKSLEIYKPRIPIVYNCSGYTSPKTLSMLDGLVDIYLPDFKYADDFLAVKYS
                     SAPNYVNTAVAAIHEMTFQVGLPQFDDDGIMKKGVIVRHLILPAHTKNSLEVLDIVKRR
                     FGDQVLLSLMCQYIPMGKVSDREFSRINRKITRREYDKVKLEMMRLGIDGFTQELSSAD
                     ESYVPEWDFEG"
     CDS             complement(1857..3590)
                     /locus_tag="ctg4_114"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIECGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     E"
     CDS             complement(3605..4090)
                     /locus_tag="ctg4_115"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(4112..4900)
                     /locus_tag="ctg4_116"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAVESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(5023..6315)
                     /locus_tag="ctg4_117"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             7046..7363
                     /locus_tag="ctg4_118"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             7376..9700
                     /locus_tag="ctg4_119"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCANCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKITETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINHDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTALDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_120"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.6e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_121"
                     /sec_met_domain="ALS_ss_C (E-value: 2.9e-29, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_122"
                     /sec_met_domain="IlvN (E-value: 1.3e-82, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 9.2e-60, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13621..15459)
                     /locus_tag="ctg4_123"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGAKLTWNKVNGVAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLGDTTGTTMLDMNVVSKEFD
                     LSVDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGARSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHQSEWMPSLGSNHNLSGVMFLDFDFDGVPELVAQKADSNEYS
                     FHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLNVDDGYYWSGNSIITY
                     DGENLFANMYSARGVGEESNNNIYYRYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTE
                     FIATGYGDASVWGEKTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(15892..18297)
                     /locus_tag="ctg4_124"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGRKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCISADGKSFTSGYDSKGTTVKYIA
                     APEISKLENVNGGVKITWNKVSGASKYRIYQKNSSDWFRVSDTTSNSIVDKSVDVGTYT
                     YTVRCISDDGKSFESGFNPKGSSIRYIQAPKILETNVVNGGIKVIWDSEENTNYRLYCK
                     TEGKGWTKVCDSKTGVVTHKNLQPNKTYTYTVRAISSDAKKYLSGYDPEGMSAKYVATP
                     KISKAEYTYDGIKLAWNKVAGAEKYRVYYKDATGWNKLVDTKGTSYLDKGLVSRELSVK
                     DSSVNGQYIYTVRCISSNGKVFQSGYDTKGVKSALYNNGCPEIYNIDTMHGGITLNWEA
                     AADKISKYRVYIKQNGSWKKLADTTNNYYTHKNVKAGQTYTYTVRCVSKDGKKFTSTYN
                     PSGVAFKYKTTNKTRDAYIDYLLKHESEWLPELKVGDIALAGVQFTDLDFDGVPELIAQ
                     EAGDKEYYLNARVYTFKNGKLSLVGFDNSMTYIQNRLAYLYDKSAKRYVINSAELSTSN
                     PDRYLDCENYTLSYDGNLISAHPYSSYHLALENWGLDYTYYVHGRTSKQVYNAANLSTL
                     DNCVNAHMYSQFVYCSVDGYPKLWNQFTTDQKRQYLTDSYNAFSYDKY"
     CDS             complement(18494..19507)
                     /locus_tag="ctg4_125"
                     /transl_table=11
                     /translation="MKKLLTALIAFVMCFSVVTTAFAATPDETSDPDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTVSYPRDCPVLLYK
                     NNKVYTLSDAYETGVINDDMLYELYVWGNLWGKIDVTPKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDKTVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TKPVSTSDTATNDTLSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK"
     CDS             complement(19701..20708)
                     /locus_tag="ctg4_126"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDEASDSDLISDIKQAMLDT
                     YYGDEKPEYLNVEILLDDEDEVYFSFSDSFATSANRVYTEAGNYIVSYLENCPVALYKN
                     NRVYMIPDAYNSGVIDDDTLEGLTYCGHMDIVPKSDDSALVIEIKNKVIEECFDGKSPE
                     TLRIDIVGRTSDGGVYFKHSVGGGIDVMVEETIGDYTYSYTHGDDVMLYKNGNVYSIKE
                     AYESGVIDDSILEELSKMNFGLKSNKPNTTVPTEPTTTVATVDEPVTVPDTTSATSATK
                     PGSTSDTATNDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNHFE"
     CDS             complement(20903..22306)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_127"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-48, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.5e-53, bitscore:
                     175.2, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPAFQKKIIGDKKI
                     IKGRPADQLKPELDKLRGEIEQWIEQPEDVLSYAQFPKVSLDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             complement(22337..22672)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.1; E-value:
                     6.5e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_128"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.2e-20, bitscore:
                     66.1, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAPAGAQGSVVV
                     KAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVDVAKGESVDSG
                     KVLVTLN"
ORIGIN
        1 gcacagataa agacttatac aaagcaacaa ttaactatta ttgcaatatt tcagcaatta
       61 actgtcgccg atatgttatt tgccgtttgc cgaaaaatcc gactgcactg aaattatata
      121 ccatatgtaa tactttgtta catattatta agattttatc gaactaaagt ttttattgtt
      181 ataaaattct ttaactgtgg tttacattta tttgtcatta tgtacaattt attactgata
      241 catcaccatt tgtttacaac ttaacaatat ttttgtaata atattgacaa tatcgcaaca
      301 taatagtatt attatcttgt gaccggttgt caaccggagg ggaaaaatga taacctacaa
      361 attgaatcat acacccgaag acgggtttaa cacctttggg ataagcgcat tttgcggcaa
      421 aaagcttata aaatccgtgt cgggaatcag cgaaagcttt cgtgaaatga cggagcttgt
      481 cgaaatgtgc aacgaacttg agcttgaact ctgccagctt gacgatatca tcgaagatta
      541 tcttactgat ttcacacttt aatttgcaaa ggctttaact tttgtcataa tcgtggtaca
      601 atagtgttta atgttctatc agacattata tatcagataa taaggtgata tcatgatttg
      661 caatttatgt ccgagaaaat gcggtgcggt tcgtactgcc cacagcggaa acggattttg
      721 taaaatggga gaactgcccg ttgttgcaag agttgctccg cactatggcg aagaaccgtg
      781 cataagcggc acaaagggca gcggaactgt tttcttttcg ggctgtacaa tgagatgcgt
      841 gtactgccag aactacgaaa tttcaaacga ggacggcgga agaacaatca ctcccgaaag
      901 acttgccgaa tgttacaaag aacttgagga caagggagtg cataacatca accttgtaac
      961 ggctgaccat tttgcacacg ctgttgttaa aagtcttgaa atttacaaac cgagaattcc
     1021 gattgtatat aactgcagcg gatacacaag tccgaaaact ctcagtatgc ttgacggact
     1081 tgttgacatt tatcttcccg actttaaata tgcagatgat tttcttgcgg taaaatactc
     1141 ttccgcaccg aattatgtca acacggctgt tgccgcaatt cacgaaatga cttttcaggt
     1201 tggtctgcct cagtttgacg atgacggcat tatgaaaaag ggcgttatcg taaggcatct
     1261 gattttgcct gcccacacaa agaacagtct tgaagtgctt gatattgtaa aacgcagatt
     1321 cggcgatcag gttttgttaa gtcttatgtg tcagtacatt cctatgggca aggtcagcga
     1381 cagggagttt tcacgaatta accgtaaaat cacacgcaga gaatatgaca aggtaaagct
     1441 tgaaatgatg cgactgggaa ttgacggctt tacacaggag ctttcttccg cagatgaaag
     1501 ctatgtcccc gaatgggatt ttgaaggatg attttttgat taatggaact cttgtagcgg
     1561 cgaaccgtgt tcgccaatca tttcgtatgt aaatacgaaa tgagcaaaaa acaagctttc
     1621 cataataatc caattaattt tattggaaca tatgtatcct gtcgaaacga ttttacaatc
     1681 gttccgattg gcgaacgagg ttcgccgcta cgaatgaata cacaattttc ttcttattaa
     1741 aatctatgtg tttgaacata taatatcatc agggtgggcg tccaatgaac gcccctaccg
     1801 attaattttc aaaaacaaaa cggtcaagaa acatttttta gtttcttgac cgttttttat
     1861 tcaaccgttt gtgacggttt tacatacagg gttttgttgt tgacataaat caccatacct
     1921 ggttttgagc cgtttggctt tgacacatag cgaacaagtg tgcagtcaac aggaacctga
     1981 ctgctgtttc tcgccttact gtgatatgcc gcaagccgtg ccgcctcgta gattgccgtg
     2041 tcggaaatct ctttgccgtc cgaaacaaca attacatgag aaccgtgaat gtcctttgtg
     2101 tgcagccaca tatcgttctt tgacgctgtt ttcaaagtca gcttatcatt ctgacggttg
     2161 tttcttccga caaggatttt aaaaccgtcg cttgattcaa attcgagcgg cggcaaagtt
     2221 gtctgacggg gctttttgcc cttttgaacc ttgagatagc cctgctcggt aagttcctca
     2281 cgaatttgcg caaggtcttt ttcattctcc gcacggtcaa ccgtatcgag aaccgagtta
     2341 atataatcaa gctcttccct gcccttttca agctgttctt tgagcataat ttcggcattt
     2401 ttagccttgc ggtaatcctt gtaatacttc tgggcatttg ccgaaggtga gattgccgga
     2461 ttaagcttta tgcgtaaaat tgcgttgttc tcatcgtaaa agttttcaac atcaacatac
     2521 tccgcaccac actcaatgcg atagatattt gcctgtaaaa ggtcaccgca tatgcgaaga
     2581 tgctcacggt ctgcacagcg ttcaagctca ctcttctgct ttgcaatttt tcgggcaagc
     2641 ctttcaagtg tgttgttcaa aagctttgta aggctttgcg atttcaccct cattctgtca
     2701 cgactgtcac gagcttcata gaatccgtca agcaaatcgg agaagctttc cttactctca
     2761 acctttgcaa aatcgccgta ctgctcaaca ttcataaagc agaagtccat aggcttgccg
     2821 tcctcacgat aaaccacaac aggcttgccc gaacaatcac tgcaaacgct tttcagcttt
     2881 tcaatttcaa ctgcgagtcg gtcaaaaagc acaccctcaa ttctgtttgt tgcgccctcc
     2941 ataaccttgt attcaatctc acggcacaca atcggagaaa cgccctcaat tgtccttaac
     3001 agcgccttgt taagcggcat ttccgtgtca agatttttta cggctgtaca cacatcaagc
     3061 accgaacatt taagcagatt cagcttgttc tgcgattcgg gaagttcgta ttttatattc
     3121 ggcagtacaa gccttttact gctcattgta agatctacac gcttgagtga atcgatgatg
     3181 acgccgtttg aatcgacaat aattatgttg ctgtacatac ccataatttc gcatacaaca
     3241 gttatcatca cagtatcgcc gagttcgttc acgcactcaa aatcgagcat aagaacacgg
     3301 tcgcaaccgt tctggcgaag tcccacaagc tttccgccgc cgattctttt tcgcaaaagc
     3361 atacagaaca tcggaggttg tgcaggattt tcgggtgttg acgaacagaa gttcactctc
     3421 ggtgaatttg ctcgtgcaga aagcaacagc tttttattgc cggaaaatgt tctcaacccg
     3481 aacacaagct cttctctgtt cggctgataa atctgcgaca cccttgcacc gagagcctct
     3541 ttttctattt cacttttaat atgtcttaaa aaaattccgt caagcgccat agtaactccg
     3601 taaattattt gtgatattta ccgtttgatg aaatctcaaa cgcacggtaa atctgttcgc
     3661 ttaaaatcat tcttgccatt tggtgaggga aggtcattct gctcattgaa agacggacat
     3721 ccgcccgttt tttaaccgat tcgtcaagcc cgtagctgcc gccgataata aaatcaacgg
     3781 tgctttttcc gcttacggac gcattgtcaa tcagctttga aagctcctca ctcgacatag
     3841 actttccctc aatacacatg gcaacaacat aatccgaagg cgaaattttt tgcatgattc
     3901 gttttccctc agagaaaata acctcatcaa tctgcgacct attcggtatg ttgctcttaa
     3961 tgcgttcttc cgaaagctca ataatattga atttacaaaa tgcggtcaag cgttttgcat
     4021 actctgcaat tgcgtcggta aaatattttt ccttgatttt gccgatacaa attatgttaa
     4081 tcttaatcat attcctcttg tttgtttaag gttaaaagat gatggctttt gttgtgctta
     4141 cactcggagc aacatcaagc gaataatcgc ttttgtactt cattccgttt gatgtgagca
     4201 ggtctacgga tgttgacatt gcaagcggaa cggtattatt ttcttcgctg agatgaccga
     4261 gcataagtct taaagttccc ttttcaacaa ggttaacaag ttcttttgca caagcctcat
     4321 ttgaaagatg tcctctgttt gaaaggattc tctgctttag cggataagga taaaatccgt
     4381 ttttgagcat attgatatcg tgatttgact caagcacaac aaagtcgctc tgctctgcgg
     4441 cagttctgac atcgggcaac ataacgccca tatcggttgc tataagtgcg gattttccgt
     4501 cgggagcagt aacacggtaa caacagcttt ccaccgcatc gtggggggtg tcaattcgct
     4561 gaacacgcat attgccgatt acaacctcgt cagttataac atctgcatct gtgtttggat
     4621 caagcttatt acctgccctc aaagcattga gcgtaccaag acttgaatac accttaaagc
     4681 cgtaacgctt tgcaagcaca cgcaacgcac tgcaatggtc agtgtgttcg tgagttataa
     4741 aaaccgcccc gatactgccc atatcaagtc cgtttgcaag catggcattt tcaatctgct
     4801 tgcatgaacg gcctgcgtca atcagtacgc cttcgcttgc cgaacctatg tagtagctgt
     4861 tacccttact tccgctgaat agcggtactg ctcttgccaa aacaatcaat ccttatcttt
     4921 agtataacga atatgataac acaaatttta aaatttgtaa attatctcac aaaaaagccg
     4981 ttctcacaaa gaaaacggct ttgatttcta attaaatttt agtcaggcac cgagctcttg
     5041 ctcgttgtct cctgtaaaat acaccttttt gatatctgca ccaagtcctc tgaacttttc
     5101 aacaacatct tcatatccac gctcaatgaa ctgaatattt gaaatctctg ttgtaccgtt
     5161 aatttcaaga gcggcaataa tcatagccgc acctgcacga aggtcggttg ccttaacggg
     5221 agccgctgtg agcggaacac cgccttcaat gattgcaagt ctgccctcaa cagaaatctg
     5281 cgcacccatt ctgataagct cgctgacata ctgatagcga ttatcccaaa cattctcgtt
     5341 gatgatgctt gttccgggaa cgctcataag caatgcggca aactgcggct gacagtctgt
     5401 cggaaagccg ggatgcggca ttgtcttgat gttacagcgc tttagcggag cagatgacgc
     5461 atcaaccttg agagcctcat catattccgt aatcttaaca cccatctcac gcagctttgc
     5521 gctgattgat tcaagatgct tcggtgtaat attctttacc gtaatacaac ctcttgttgc
     5581 ggcggcggca cacatatatg ttcctgcctc aatctggtcg ggaataatcg aataagtaat
     5641 tccgtgaaga tactcaacgc cacggatttt gataacatcc gtacctgcgc ccctgacatc
     5701 cgcacccatt gaattaagga agttcgcaag gtcaacaata tgcggttctc ttgcggcatt
     5761 ttcaataatg gtctgtccct ttgcctttga tgcggcaagc ataatgttca ttgttgcacc
     5821 aacggacaca acatcaaggt acacatgtgt accgacaagg ctgtcgcatt ctgcctctat
     5881 aatcgcaccg tcaacaagct gagttgtcgc accgagagcc tcaaagcctt taagatgctg
     5941 gtcaatcgga cgcacgccaa agttacagcc gcccggaaga gccaccttag ccttgccgta
     6001 cttgcccaaa agtgcgccga gaagataata tgacgctctc atacctctta caaggtcggt
     6061 cacagcattg catgtgcgga tttttgtagg atcaatatat aaggacgaac ggttgattcg
     6121 tcttacatta gcacccatct gctgaagaat tctgctgata agtgatacat cgctgatgtt
     6181 aggaatattt tcaatctggc acggttcatc acaaagaata actgccggaa taattgcaac
     6241 ggctgcattt ttcgcaccgc tgattgtcac ttcacccgat aatggctttc cgccggtaac
     6301 tacgaacttc tccaattgtt acaccccaat taatgtgtag aagatacttt taactaaata
     6361 agctaaatat ctgaaaatgt atatctatat agtgtataag taaaaatcaa aaattatacg
     6421 aatctaaaat tcataatgag aactaatttg ttacatttta ttaaaaacga acccactcgg
     6481 ttacgcagat gtaatttaac aattctctta cagaaaatga tactacaaaa ttgtagtaaa
     6541 gtcaacggaa taataaaact gtaatctatt tttgggcaag ttgtactcaa attattaatt
     6601 tgttgctttt tttgttttta atataaccaa ccatgctttt taaaaccgtt ttttcctaaa
     6661 aagaagtaat taatcaaagc gattttttgt aaaattatta caaattgaaa caagtgttat
     6721 tttcgtgtta tcatcaggca tctgagcatt ttacaattca aattgaacac agaaaaatat
     6781 cgttccgtta ttcctacgat aattttacac cttcaatctt cttttttcaa atttaaaatt
     6841 aactttctat actatatata ctttccaaac ggacacaata aacaagtgaa actttggggc
     6901 aaaaaaactt gaaaaacatt acattttttc gtgtgtgtct attgactttt taaaaaggaa
     6961 atgctatatt ataattaaca tatgagcata tcttcatatg ttcaagtata actattaacc
     7021 tgagagaaaa ttaaagggga cgcctatgga aaacaaagaa aaaacaacca ctcccgaaat
     7081 gcccgacatt gatgtgctgt ttgagcttgc agaccttttt aaggttttcg gtgattcaac
     7141 ccgacttcgc attatgtaca ccatttcgga aaatgaaatg tcggtgctca acattgctga
     7201 agctctcagc atggagcaaa gcacaatttc ccaccaactg cgtgtgttaa ggcagaacaa
     7261 gctggtgcgt gttcgccgtg aaggaaagca gatttattac agccttgacg atgaccatgt
     7321 gaaacgaatc atagaaatgg gacttgacca tgttcttgaa taaggaggga gacatatgag
     7381 gtacaaatat cagcttgaca atctcaactg cgctaattgt gcaggcaaga ttgaggctaa
     7441 aattgcagaa acaaacggct ttgaggatgt gagctttaat tttgcgacaa aacttctcaa
     7501 cttcaaaagc gaaaagcaga atcctgtttc cgaaattcag gcaatttgcg acagcattga
     7561 ggacggtgta accgttgttg acaaaactcc gaaaaccaat ctcaaaaaat acacctacac
     7621 tttagacaat ctcaattgcg ctcattgtgc aggcaagatt gaggctaaaa ttacagaaac
     7681 agacggcttt gaggatgtaa gctttaattt tgcgacaaaa cttctcaact tcaaaagcga
     7741 aaagcagaat cctgtttccg aaattcaggc aatttgcgac agcattgagg acggtgtaac
     7801 cgttgttgac aaaactccga aaaatgatat cacaacaaag gcagaacccg aaatcacgaa
     7861 aaagaaaatc aaccatgaca caatcttcct tgcaatttca attgtacttg ctgtagtgtc
     7921 cgaaattctc caccttacac ttgacggtgt tacggctgtt cattatgttg tactcgcagc
     7981 gtgttttgtt gcaacacttc tttcgggtta caaggtattt atcaagggtg caaaaaacat
     8041 tctaaagctg agaattgacg aaacaacgct tatggctgtt gcggtaattg cggcattctg
     8101 tcttggagat tttgttgagg cggcaatggt aacaatcctc ttttctatcg gtgaaatttt
     8161 tgaggatcga gcagttgacg catcccgccg tgacattgaa aagcttgcaa acattcgtcc
     8221 cgatacagca acaattattg ttgacggtgc ggaacagatt gttcctgccg aaagcgttga
     8281 aatcggaagt atcattgaag tcaagccata cgaaagagtt ccgcttgacg gcattattat
     8341 taaaggtaaa acggctctcg acacatcggc tctcacaggc gaaagccttc ctgttgatgc
     8401 aggcgagggc agtgaggtac tcagcggtgc aatcaacggc agtaacctta ttactgtcaa
     8461 aaccacaaaa catttcggcg acagtaccgc aacaagaatt cttcagcttg ttgaagatgc
     8521 cgccgctcaa aagggcaaca gcgaaaagct tatttcaaga tttgcctctg tttacacacc
     8581 ggttgttgta ctcattgcag ttgcaatcgc agtaattcct ccgctctgcg gactcggagc
     8641 attcagcgaa tggctatacc gtgcgcttgt ttgtcttgta gcgtcatgtc cgtgtgctat
     8701 tgttatttcc gtacctctct cctactattc gggtatcggt gcggcatccg aagtcggtgt
     8761 actcatcaag ggcggaaaat atattgaggc tcttgcaaaa gcagacacat tcgtattcga
     8821 taaaacaggc acactcacaa gcggcaagct cagcgtaaac aaggttaata ctgtcggttc
     8881 atacagtgct gacgaagttc ttgctcttgc cgctgcaagc gaaaaatatt ctgctcatcc
     8941 gattgcctcc gcaatcagag agaaggcaaa cggtcttgaa cttcccgagc tttccgacta
     9001 cagcgaaagt gccggtcacg gaacaagcgc agtttataac ggcaaaacta ttcagtgcgg
     9061 cggttcaaag attctttcgg acgaacagaa gaagattgca aataaagacg attctgtttt
     9121 cgtaatttat gacggtcagc ttatcggttc gctcaatgtc agcgatacag taagacctga
     9181 ggcaaaagag gttatctcac agcttaaagc gctcggtgtc aagaacacgg taatgctcac
     9241 aggcgacaga caacagcctg ccgaaaatgt taaaaacgaa ctcggacttt ccgaatgtca
     9301 cgcagagctt ctccctgctc aaaagcttga gcttttcaag ggcttgaaat caaaatccaa
     9361 gggtgcttgc tttgtaggcg acggcatcaa tgatgcccct gttctttcgg caagcgactg
     9421 tggtatcgca atgggattcg gcagtgaagc cgctattgaa gcgtcagacg cagttctcgc
     9481 atcaggcaca ctcaagcagc ttccaaaggc aattaaaatt gcaagaagtg ttatcaacac
     9541 tgtcaagggc aacatcatct ttgccctctc aatcaaggct cttgtaatca tcctcgccgc
     9601 attcggtctt gcacaaatct ggatgtccgt tatcgccgac acaggcgtca gcgtagtctg
     9661 cgtcctcata gccgcaagac tcctcaaaaa gaaatattga tttcctcaac aatcattact
     9721 gttcccgagc aggtaaaact gttcgggaat tttcttgtta ttactcttat acagatactt
     9781 ttttgggcag cattttgctt ttgttgttaa tcatttatta tatctttttc aggcgatgac
     9841 agaataattt aaaatcctgc aaaaaattta atttatgggc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag taaaaaggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatctgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggtattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacggg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga atactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg tatcaagctt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggtactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt atttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagcgcga tgttccgctc aaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgctgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caaaggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtacacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaga tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc actcgcagta ggtgttactc aggaaccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagcttaac aagctcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgttttaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aggcgaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 taaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cagcagaggc
    12421 tgcaaagcag gctgacatca ttatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 taagaacgac atcgagccaa acctcgaagc aggcaatatg cttatgttcg ctcacggctt
    12541 taacattcac ttcggttgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggaccg ggtcacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgctgtt gagcaggatg ctacaggtca ggctaaggat ctcgcactcg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgaacagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg caggttacga cccaagaaac gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaag gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagat
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaagtta gtttgatata
    13261 ttcaaacttc tgtcacccga gctttaacat agtacgaatt tagggtagct tgattttcaa
    13321 gctacccttt ttgcgagtac ctcgctcgta gttcgtgtag gtagtttgtg ataatttaca
    13381 actacttgtt cccgagctta acatagttat aattttcaag ctaccctttt tgcgagtacc
    13441 tcgcccgcag ttcgtgtagg tagtttgtga taatttacaa ctacttgttt ccaagcttaa
    13501 catagtacag attaacggtt cagtcaattt ggctgaaccg tttttttgtt gtgcaataaa
    13561 agggttcagc tttttacggc tgaacccttt tgcagttaaa acttattaat ttttaaataa
    13621 tcaatacttc tcataggaga aagaattata agcgtcaagc aaagactgct tattctcagc
    13681 ggtagttttc tcaccccata cgctggcatc accataacct gtcgcaataa attcggtaaa
    13741 catatgtgca tttacgcaat tattaaactg tttaaggtta atttcgttat attttgcccg
    13801 tgaaatattt ttgtcattac cgtcaaaata tctataataa atattattat ttgattcttc
    13861 gcctacgcct cttgccgaat acatatttgc aaaaagattc tctccgtcgt atgtgattat
    13921 tgaattaccc gaccaatagt aaccgtcatc tacatttaaa gatatcttta ggtcgtgaac
    13981 ctcatacttt ttggcagttt tattatagta tatcgcaaaa ccgtcgttaa catttcccac
    14041 tctttttaac ttaccgtctt caaatttgta aacaacggaa tggaaactat actcattgga
    14101 atcagccttt tgtgcaacaa gctccggaac tccgtcaaag tcgaaatcca aaaacataac
    14161 acctgacaaa ttgtgattac ttcccaagct tggcatccat tcactctgat gattcatcat
    14221 ataattgata taagcgtccc ttgttttatc ggatgtctta tatctgtatg ttacaccggt
    14281 tgggttaaac atcgtagtaa actttttacc gtcttttgaa acacctctta ccgtataagt
    14341 gttactgccg gaccttgcac ccttgtgaac ataatagttg tcataagttt ctgctatctt
    14401 cttccaagaa ccgttttctt taatataaac acggaacttt ggcgcatctc ccgtccaatg
    14461 catttcaaca ccgttgttta ctgcaccaat gctgtaaatt tcgggacaat cctgatgatc
    14521 gccaattggc gtaccctttg aatcgtagcc gcttgtaaaa ctcttggcat ccttgctgat
    14581 acaacgaacc gtgtaataaa tatcatcaac gcttaaatca aattcctttg aaacaacatt
    14641 catatcaagc atagtcgtgc ctgttgtgtc gccaagcttt gtccaaccgt tcctgtcctt
    14701 gtagtacaca cggtattttt ctgcacctgc gaccttgttc catgtcagct ttacgccgtc
    14761 atatgtaacc tcaagttttg aaattttcgg tgtggcaaca tactttaccg acttgcctgt
    14821 cgggttataa ccgcttgtaa atttctttgc gtctgatgta atacatctta cagtataagt
    14881 gtaatttctg cccgatgaaa catccttgtc gatatatgag gttgaagttg tatcgaccat
    14941 tcgtgtccag cctttactgc ccttgtagta aactctgtat ttagtcgcac cgcttacttt
    15001 gccccaagag attttcacac cgccgtttac attttcaagc tttgaaattt cgggggcagc
    15061 aacatatttt acagttgtcc cctttgaatc ataaccgctt gtaaagctct ttccgtcagc
    15121 agaaatacat cttacagtat aggtgtaatt cctgcccgat gaaacatcct tgtcgatata
    15181 tgatgttgaa gttgtatcga ccattcgtgt ccaaccttta cggcccttgt agtaaactct
    15241 gtatttagcc acaccgttca ctttgttcca tgtaagcttt gcaccgccgt aaacgctttc
    15301 ggcttttgaa attttcggag tagccaggct tgcccttgca acctgtgcat actgcacagg
    15361 tgtgttaagc ggttcaaccg catttgcaga aactgccgaa accgcaaccg cagacatcga
    15421 cattaccgcc gccatagcta taggtaaaaa ctttttcata tctatccctc actttgttca
    15481 aattctacgc attattaaaa acttttgcta aatttttatg catgttaatt gtaacattaa
    15541 atgatataaa aagcaataca tcttgataaa ctatcacaaa ttttttaagc taaaataaat
    15601 aaaccgctct caataacgag aacggctttt attatgtcaa aacatatgag catcaacata
    15661 aatttcatca aagcgggcgg ataatatccg cctctacaga attgttcaaa tggtagctat
    15721 attacgctcg ggcataaata ttttttattc gtcgaacttc tgtaaccaga gcgttgtata
    15781 gtacgaatta acggttcagt caatttggct aaaccgtttt tgttgtgcaa taaaagggtt
    15841 cagcttttta cggctgaacc ctttaccgtt ataatttatt acttttagga atcaatattt
    15901 atcatatgaa aatgcgttgt aagaatcggt aaggtactgt cttttctgat cggttgtaaa
    15961 ctgattccaa agttttggat aaccgtcaac agaacagtaa acaaactgac tgtacatatg
    16021 tgcatttaca caattatcga gtgtactcaa gtttgcagca ttatacactt gtttgcttgt
    16081 cctgccatga acataatagg tgtaatccaa tccccaattt tcaagagcta aatgataaga
    16141 agaatacgga tgagcactta taaggttgcc atcataactc aatgtatagt tttcacaatc
    16201 aagataacga tcgggattgc tggttgataa ctcggctgaa tttatcacat accttttagc
    16261 cgatttatcg tataagtagg ccaatctatt ctgaatgtag gtcatagaat tatcaaatcc
    16321 aaccaatgaa agctttccat tcttgaaagt atataccctt gcattcaaat agtattcctt
    16381 atcccctgct tcctgcgcta taagctcagg aacaccgtca aaatcaaggt ctgtaaactg
    16441 cacaccggcc aaagcaatgt cccccacctt gagttcaggc aaccactccg attcatgttt
    16501 aagcagataa tctatatatg catctcttgt tttgttggtt gttttatact taaatgcaac
    16561 acctgacgga ttataggtac ttgtaaattt cttaccgtcc tttgacacac atcttacagt
    16621 ataagtgtag gtctgtcctg cttttacatt tttatgagtg taataattat ttgttgtatc
    16681 agcaagcttt ttccacgaac cgttttgctt aatataaact cgatactttg aaattttatc
    16741 agcggcagcc tcccaattta aggtaattcc tccgtgcatt gtatcaatat tataaatttc
    16801 cggacatccg ttgttatata atgcactttt tacacccttt gtgtcataac cgctctgaaa
    16861 aactttgccg ttacttgaaa tacagcgaac agtataaata tactgaccgt ttacagaact
    16921 atcttttacg ctgagttctc ttgaaacaag tcccttgtca agataacttg taccttttgt
    16981 atctacaagt ttattccaac cggtagcatc cttataatat acacgatatt tttcagcacc
    17041 tgcaacctta ttccacgcaa gcttgatacc gtcatatgta tattctgcct ttgatatttt
    17101 cggtgtggca acatattttg cgctcattcc ctcagggtca taaccgctca aatacttttt
    17161 agcgtcggaa ctgattgctc ttacagtgta tgtataggtc ttattcggct gtaaattttt
    17221 atgtgtcaca acacctgttt tgctatcgca tacttttgtc cagcccttac cttctgtttt
    17281 gcagtacaat ctgtaatttg tattttcttc agaatcccaa atcaccttaa taccgccgtt
    17341 tacaacattg gtttcaagta ttttaggagc ttgaatatat ctgatacttg agccttttgg
    17401 gttaaatcca ctctcaaaac tctttccgtc atcacttata cacctcacgg tataagtata
    17461 ggttcccaca tcaacagatt tatcaactat agaattagaa gtcgtatctg atactctgaa
    17521 ccaatctgac gaatttttct ggtaaattct atactttgat gcaccgctta ctttgttcca
    17581 tgtaattttc acaccgccgt ttacattttc aagctttgaa atttcggggg cggcaatata
    17641 ttttacagtt gtcccctttg aatcataacc gcttgtaaag ctctttccgt cagcagaaat
    17701 acatcttaca gtataggtgt aattcctgcc cgatgaaaca tccttgtcga tatatgatgt
    17761 tgaagttgta tcgaccattc gtgtccaacc tttacggccc ttgtagtaaa ctctgtattt
    17821 agttgcaccg cttactttgc cccaagagat tttcacaccg ccgtttacat tttcaagctt
    17881 tgaaatttcg ggggcagcaa catattttac agttgtcccc tttgaatcat aaccgcttgt
    17941 aaagctcttt ccgtcagcag aaatacatct tacagtatag gtgtaattcc tgcccgatga
    18001 aacatccttg tcgatatatg aggttgaagt tgtatcgacc attcgtgtcc agcctttacg
    18061 gcccttgtag taaactctgt acttagccgc accattcact ttgttccatg taagctttac
    18121 accgccgtaa acgctttcgg cttttgaaat tttcggtgtt gccaagcttg cccttgcaac
    18181 ctgtgcatac tgcacgggtg tgttaagcgg ttcaaccgca tttgcagaaa ctgccgaaac
    18241 cgcaaccgca gacatcgaca ttaccgccgc catagctata ggtaaaaact ttttcatatc
    18301 tatccctcac tttgttcaaa ttctacgcat tattaaaaac ttttgctaaa tttttatgca
    18361 tgttaattgt aacattaaat gatataaaaa gcaatacatc ttgataaact atcacaaatt
    18421 tttaagctaa aataaataaa ccgttcacaa aagcgagaac ggtttatttt atatattctg
    18481 ttgatatttt gaattattta aaataatttc tgcgttttgc aaaaattact gcacaacctg
    18541 caagcattgc aacaagaaga attacagcaa cgctgttctg tcctgtctgt acagcaccgc
    18601 tgttattctg tgaattgctc agtgtgtcat ttgtagctgt gtcgcttgtt gaaacaggct
    18661 tagttgccga agttgtatcg ggtactgtta caggttcgtc aactgttgca accgaagttg
    18721 taggctcagt aggaacagtt gtattcggtt tattagattc caaaccaaaa ttcatttttg
    18781 acaattcttc aagaatacta tcgtcaataa ctccgctttc ataagcctct ttaattgagt
    18841 aaacattgcc attcttataa agcataacat catcgccatg gttgtaataa taagtatagt
    18901 caccaattgt ttgttcaatc ataacgccta aactcataaa gggtatattt ctaaaacata
    18961 ctgttttatc acttgtagaa ccaacaattt cgacattcaa atattcaggt gctttgccat
    19021 tgtaatattt atttataatt acacgcttta tttctgaaag gagagctcta tcttcaccct
    19081 ttggggtaac atctatctta ccccaaagat ttccccaaac atataattca tagagcatat
    19141 catcattaat tacacctgtt tcataggcat ctgacaaggt atatacttta ttattcttgt
    19201 ataacaaaac gggacaatct ctcggataag aaacagtata atcacctata tcgaattcca
    19261 cttcatctgt ccagtgtgta aaactatcca taaaatcgaa atacacgcca ccgtcactgg
    19321 ctgtaccata tattcttact tcaataaaat caggcttttc atcgccataa tatgtatcta
    19381 acatagcctg tttaatatct gaaatcaagt ctggatcaga agtttcatca ggtgtagcag
    19441 caaaagctgt tgttacaacc gaaaagcaca ttacaaatgc tatcaatgca gttaaaagtt
    19501 ttttcatttt tatttcctca tcttttattt attctatctg taataatggt atatgcaaca
    19561 gatattcaat ttactttatt ataccgctaa aatacatgta atgcaatata gttgctaaaa
    19621 attcacataa aataatcagc aaaataaaaa ccgttctcaa taacgagaac ggcttttata
    19681 gggattattt aatttgtaaa ttactcaaaa tgatttctgc gttttgcaaa aattactgca
    19741 caacctgcaa gcattgcaac aagaagaatt acagcaacgc tgttctgtcc tgtctgtaca
    19801 gcaccgctgt tattctgtga attgttcggt gtgtcatttg tagctgtgtc gcttgttgaa
    19861 ccaggcttag ttgccgaagt tgcagaagtt gtatcgggta ctgttacagg ttcgtcaact
    19921 gttgcaaccg tagttgtagg ctcagtagga acagttgtat tcggtttatt agatttcaaa
    19981 ccaaaattca tttttgacaa ttcttcaaga atactatcgt caataactcc gctttcataa
    20041 gcctctttaa ttgagtaaac attgccattc ttataaagca taacatcatc gccgtgagta
    20101 tagctgtaag tataatcgcc gattgtttct tcaaccatta catcaatacc gccgcctacg
    20161 ctgtgtttaa aatatactcc gccgtcactt gttctgccaa caatatcaat tctcaaagtt
    20221 tcaggtgatt tgccgtcaaa acactcttca ataactttgt tttttatttc gataacaagt
    20281 gctgaatcat cgcttttcgg aactatatcc atatgtccgc aataggtcaa gccctcaagt
    20341 gtatcgtcat caataacgcc tgaattataa gcatcgggga tcatataaac cctgttgttt
    20401 ttgtacagtg ccacaggaca attttcaagg taagaaacta tgtaattgcc tgcctcggtg
    20461 taaactctgt ttgcagaagt agcaaagctg tcagaaaaac tgaaataaac ctcgtcttca
    20521 tcgtccaaaa gaatttcgac attcagatat tcaggctttt catcaccata atatgtatct
    20581 aacatagcct gtttaatatc tgaaatcaag tctgaatcag aagcttcatc cggtgtagcc
    20641 gcaaaagctg ttgttacaac cgaaaagcac attacaaatg ctatcaatgc tgttaaaaat
    20701 tttttcattt ttatttcctc atcttttatt tattctatct gtaataatgg tatatgcaac
    20761 agatattcaa tttacatcat tataccgcta aaatatatgt aatgcaatat agttgctaaa
    20821 aatttagcaa gaataattct gcccaaatga aaatgccact ttcatagcga aagtggcata
    20881 aatgttaatt ttagttgtca aatcaaactg ggtgaaccat atttttcttg tcaagcttgt
    20941 cgccgttgat gccaaccttg gcatttcttc tcttttcaaa gaagtcgagg gaaaccttcg
    21001 ggaactgtgc ataagaaaga acatcctcag gctgttcaat ccactgctca atctcgccac
    21061 ggagcttatc aagctcaggc ttaagctgat ctgcaggacg acctttgata atcttcttgt
    21121 caccgataat cttcttctga aacgcaggat caatcggcat tggagttgta ccatactcac
    21181 cggcaacaag tcccttgaac tcgtttgtgc acattgagta gcgcttgcct gtgattacat
    21241 tgaatacagc ctgtgtgccg acaatctgtg atgtcggagt aacaagcgga ggataacctg
    21301 aatccttacg aacacggggt acttctgcaa gaacttcgtc aagcttgtct tctttaccgg
    21361 cctgcttgag ctgtgaaaga aggttggaaa gcataccgcc gggaacctga tagataagag
    21421 cgttagcgtc tgttgcgagc atcttaggat caagaagtcc tgacttgatg tacttctcac
    21481 gaagagtcat gaagtaagca cggatgtcag agaactgttt aaggtcaaga cctgtgtcga
    21541 actctgtgcc tgaaagagcg gcaaccattg actctgtagg tgcgtgtgat gtaccgagag
    21601 cgagtgggct gattgctgtg tcaatgccgt cggcacctgc ctcaacaccc tttaaaagac
    21661 acattgatgc aagacctgat gtgtagtggg tgtggagctg aagcggaagc tccggaacag
    21721 cggctttgat agcctttaca aggctttcgg ttcttgtcgg agtaagaaga gcagccatat
    21781 ccttgataca gattgaatct gcacctgcgt ctgcaattct cttagcatac tcaacatagt
    21841 attcatctgt gaatacagga cctgttgtgt agctgatagc aacctgtgca tgaccgcctt
    21901 ctttgttagc ggccttgata gctgttttaa gattcttgat gtcgttaaga gcatcaaaaa
    21961 tacggataat gtcaataccg tttgcgattg aacgctgaac aaggtactca acgcagtcat
    22021 cggcatagtg acgataaccg agcatattct gtcctctgaa aagcatttgg agctttgtgt
    22081 tagggcaatg ctctctgatt gtgcggagtc tgtcccacgg atcttcgttt aagaatctga
    22141 ggcatgagtc atatgttgca ccgccccagc attcgagtga gtaataaccg attttatcga
    22201 gtttgtcaag aacagggagc atttcctctg ttgtcattct tgttgcaatg agtgactgat
    22261 gagcgtcacg cagagcagtt tcggtaactc tgattttttt tgccatttta cagcatccct
    22321 ttctccgaat tattgattag ttaagtgtta cgagaacctt acctgagtca acagactcac
    22381 cctttgcaac atcaactgtt gcaactgtgc cgtcctgcgg agccttaaca ggagtttcca
    22441 tcttcatagc ctcgatgaat acgaggtcat ctccggcctt aacagcctgt cctgccgaaa
    22501 caacaacatt aacaactgta ccgggcatag gagcctttac aacaacagaa ccctgagcgc
    22561 ctgcgggagc tgccggagca ggagcggctg ctgcaggagc tgaagaacca ccgagttctt
    22621 caacctgaac atcatatgct gtgccgttaa ctgtaattct taaattcttc atttttagta
    22681 tcccctttta ttttaacaag taatcattta tcagatagtt gaatgcttct ttgaaagtgt
    22741 tgaaacacgc ttgcccgaga gcatatcaag agcagaaata agagtctgac ggagctgagc
    22801 ttcttcaaca ataccgtcaa catagccgtt ctgagcggca ttgtaagcag aaagattctc
    22861 gtcagcaaac ttctgagcaa cctcagcctg cttatctgtg gcaacattca taacttcggg
    22921 agccataatg aatgcggcag cctcaacatt aacaggtgaa ataaccgcat cgggaagtgc
    22981 gtaaacaaca tctgcattag cgcctgtgcc tgcaagagca acatagcctg agccgattgc
    23041 cttgcctgta acaacagaaa tcttgactgt tgttgcctca gcataagcgg ctgacgcctt
    23101 tgttgccgac ttgattgact caaagcccgg gcagtttacg aatgttacaa cagggagtga
    23161 gaaagcgtcg cagaaacgaa caaactttgc taccttgttt gcagacttgc aaccaagctc
    23221 attgccct
//
