Genome ID：GCA_000174715.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	33	38.64

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
FBGABBEI_31	12637	13374	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1
FBGABBEI_31	9611	11530	tet(M)	ARO:3000186	tet(M)	98.90	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FBGABBEI_31	12637	13374	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
FBGABBEI_31	9611	11530	tet(M)	Doxycycline, Tetracycline, Minocycline	99.64	100.00	X92947

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FBGABBEI_31	12637	13371	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
FBGABBEI_31	9611	11527	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691736.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FBGABBEI_40	77980	78695	STER_RS07085	0.0	Capsule	Immune modulation	96.51	99.86	WP_011681442
FBGABBEI_40	82004	82855	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
FBGABBEI_38	50321	51061	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
FBGABBEI_40	78697	79665	STER_RS07090	0.0	Capsule	Immune modulation	94.94	100.00	WP_011681443
FBGABBEI_38	50321	51061	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
FBGABBEI_38	51118	52483	STER_RS05300	0.0	Capsule	Immune modulation	94.00	99.85	WP_011681173
FBGABBEI_38	50321	51056	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
FBGABBEI_38	47418	48878	STER_RS05320	0.0	Capsule	Immune modulation	93.63	100.00	WP_011681177
FBGABBEI_38	47418	48878	STU_RS14650	0.0	Capsule	Immune modulation	93.57	100.21	WP_011226049
FBGABBEI_38	51118	52485	STU_RS14630	0.0	Capsule	Immune modulation	93.57	100.00	WP_011226045
FBGABBEI_38	47418	48878	STR_RS05265	0.0	Capsule	Immune modulation	92.81	100.21	WP_041827043
FBGABBEI_40	76858	77634	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
FBGABBEI_40	80632	81885	STER_RS07100	0.0	Capsule	Immune modulation	92.34	99.44	WP_011681445
FBGABBEI_38	48879	49610	STU_RS14645	0.0	Capsule	Immune modulation	92.08	100.00	WP_011226048
FBGABBEI_38	48879	49610	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
FBGABBEI_47	71979	72572	STR_RS05880	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
FBGABBEI_47	71979	72572	STER_RS06030	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
FBGABBEI_47	71979	72572	STU_RS15260	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
FBGABBEI_47	72572	73441	rfbA	0.0	Capsule	Immune modulation	91.15	100.00	WP_011681286
FBGABBEI_38	48879	49610	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
FBGABBEI_38	158608	160266	fbp54	0.0	FBPs	Adherence	90.66	99.94	WP_011227179
FBGABBEI_16	495	1400	cbpD	0.0	Autolysin	Exoenzyme	89.32	93.29	WP_082302295
FBGABBEI_40	380029	381039	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.55	99.80	WP_002986042
FBGABBEI_10	106779	108082	eno	0.0	Streptococcal enolase	Exoenzyme	88.32	99.54	WP_000022832
FBGABBEI_38	49619	50311	STR_RS05255	0.0	Capsule	Immune modulation	87.90	99.86	WP_011227247
FBGABBEI_38	49619	50311	STU_RS14640	0.0	Capsule	Immune modulation	87.90	99.86	WP_011226047
FBGABBEI_38	49619	50311	STER_RS05310	0.0	Capsule	Immune modulation	87.32	99.86	WP_011681175
FBGABBEI_35	17620	18381	srtA	0.0	Sortase A	Exoenzyme	85.21	99.74	-
FBGABBEI_47	70730	71776	rfbB	0.0	Capsule	Immune modulation	80.90	100.00	WP_009659423
FBGABBEI_15	8208	9491	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
FBGABBEI_38	63312	63895	SPD_RS01775	1.13e-157	Capsule	Immune modulation	84.13	96.04	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FBGABBEI_35	14931	13948	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
FBGABBEI_35	26516	27589	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
FBGABBEI_40	261203	263509	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.67	99.22	AAK74619
FBGABBEI_35	45575	47821	metE	0.0	methionine biosynthesis enzymes	93.06	100.00	AAK74738
FBGABBEI_31	42214	40733	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
FBGABBEI_10	201403	200435	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
FBGABBEI_71	3924	4895	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
FBGABBEI_47	98824	97094	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FBGABBEI_40	96289	94301	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
FBGABBEI_40	124649	123498	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
FBGABBEI_50	25653	27131	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
FBGABBEI_10	108082	106781	Eno	0.0	enolase	86.44	99.77	ABP90468
FBGABBEI_13	13864	15756	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
FBGABBEI_35	50739	49030	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
FBGABBEI_71	38476	39567	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
FBGABBEI_38	144144	145505	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
FBGABBEI_13	145143	144133	pdh	1.38e-178	pyruvate dehydrogenase	83.98	99.70	ABP91006
FBGABBEI_10	122501	121611	bglB	3.10e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
FBGABBEI_35	90611	89661	SP_0676	1.16e-170	transcription facot	81.39	98.45	AAK74821
FBGABBEI_35	48011	48868	metF	3.26e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
FBGABBEI_38	1735	2439	covR	8.61e-127	responder protein	85.53	100.00	AAK71319
FBGABBEI_31	115242	115913	rr01	2.89e-126	response regulator	84.38	99.56	CAB54566
FBGABBEI_35	55404	56075	ciaR	1.24e-125	two component system response regulator	86.16	99.12	AIK75708
FBGABBEI_35	55404	56072	CiaR	2.27e-125	two-component response regulator	87.44	99.55	AAK74935
FBGABBEI_84	63726	63040	CovR	1.94e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
FBGABBEI_38	1735	2439	walR	1.96e-120	DNA-binding response regulator	82.13	100.00	ANC99504
FBGABBEI_71	39742	40137	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
FBGABBEI_38	132687	132286	SpxA1	6.06e-70	transcriptional regulator	82.09	100.00	ERL19273
FBGABBEI_30	48655	49068	GrpE	4.28e-68	protein grpE	81.88	80.59	ABP89267
FBGABBEI_84	30345	30058	spr0479	2.35e-48	essential gene	85.42	98.97	AAK99283
FBGABBEI_10	234355	234101	spr1327	1.30e-44	essential gene	92.94	100.00	AAL00131
FBGABBEI_13	55629	55366	spr0175	8.97e-43	pathogenitcity related	85.23	100.00	AAK98979
FBGABBEI_13	54805	54539	spr0177	1.99e-41	essential gene	83.15	88.12	AAK98981
FBGABBEI_15	8041	7550	RopE (M5005_Spy_1611)	5.25e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
FBGABBEI_40	261203	263503	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.36	98.08	MYN69560
FBGABBEI_13	108725	109744	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451