Genome ID：GCA_000335495.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	15	32	35.34

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FOPMFGFP_100	13853	14446	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
FOPMFGFP_100	13853	14446	STER_RS06030	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
FOPMFGFP_100	13853	14446	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
FOPMFGFP_82	3445	5103	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
FOPMFGFP_100	14446	15315	rfbA	0.0	Capsule	Immune modulation	99.19	100.00	WP_011681286
FOPMFGFP_100	49219	49980	srtA	0.0	Sortase A	Exoenzyme	98.42	100.00	-
FOPMFGFP_98	19168	19962	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.11	100.25	-
FOPMFGFP_96	1458	2189	STER_RS05315	0.0	Capsule	Immune modulation	97.95	100.00	WP_011681176
FOPMFGFP_42	6650	7612	cbpD	0.0	Autolysin	Exoenzyme	97.73	99.90	WP_082302295
FOPMFGFP_96	7	747	STU_RS14635	0.0	Capsule	Immune modulation	97.71	100.00	WP_011226046
FOPMFGFP_96	1458	2189	STU_RS14645	0.0	Capsule	Immune modulation	97.68	100.00	WP_011226048
FOPMFGFP_96	1458	2189	STR_RS05260	0.0	Capsule	Immune modulation	97.27	100.00	WP_011227248
FOPMFGFP_115	9	860	rfbD	0.0	Capsule	Immune modulation	97.07	100.00	WP_014621820
FOPMFGFP_96	7	747	STER_RS05305	0.0	Capsule	Immune modulation	97.03	100.00	WP_011681174
FOPMFGFP_96	2190	3650	STER_RS05320	0.0	Capsule	Immune modulation	96.65	100.00	WP_011681177
FOPMFGFP_96	12	747	STR_RS05250	0.0	Capsule	Immune modulation	96.47	98.13	WP_011227246
FOPMFGFP_96	2190	3650	STU_RS14650	0.0	Capsule	Immune modulation	96.44	100.21	WP_011226049
FOPMFGFP_96	757	1449	STR_RS05255	0.0	Capsule	Immune modulation	96.10	100.00	WP_011227247
FOPMFGFP_96	757	1449	STU_RS14640	0.0	Capsule	Immune modulation	96.10	100.00	WP_011226047
FOPMFGFP_96	2190	3650	STR_RS05265	0.0	Capsule	Immune modulation	95.76	100.21	WP_041827043
FOPMFGFP_96	757	1449	STER_RS05310	0.0	Capsule	Immune modulation	89.75	100.00	WP_011681175
FOPMFGFP_50	81114	82417	eno	0.0	Streptococcal enolase	Exoenzyme	88.09	99.54	WP_000022832
FOPMFGFP_133	536	1546	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.69	99.70	WP_002986042
FOPMFGFP_100	12378	13424	rfbB	0.0	Capsule	Immune modulation	80.71	100.00	WP_009659423
FOPMFGFP_25	5229	6512	tig/ropA	0.0	Trigger factor	Stress survival	80.50	99.77	WP_000107753
FOPMFGFP_114	1	469	STER_RS07085	0.0	Capsule	Immune modulation	98.51	65.41	WP_011681442

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FOPMFGFP_100	52667	53650	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.51	100.00	AAK75326
FOPMFGFP_63	39020	40093	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
FOPMFGFP_126	2196	4499	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
FOPMFGFP_49	1887	2855	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
FOPMFGFP_106	17674	19155	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
FOPMFGFP_65	691	2937	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
FOPMFGFP_6	14090	15082	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
FOPMFGFP_3	4482	5453	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
FOPMFGFP_119	16990	15839	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
FOPMFGFP_117	6740	4752	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
FOPMFGFP_100	36464	34734	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.69	100.00	AAK34199
FOPMFGFP_144	25797	24319	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
FOPMFGFP_50	81114	82415	Eno	0.0	enolase	86.44	99.77	ABP90468
FOPMFGFP_144	11060	9168	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
FOPMFGFP_65	5862	4153	PGM	0.0	phosphoglucomutase	83.36	99.65	ACH87041
FOPMFGFP_137	21455	22465	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
FOPMFGFP_83	2629	1268	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
FOPMFGFP_137	71776	69884	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
FOPMFGFP_50	66674	67564	bglB	6.92e-180	putative phospho--glucosidase	88.89	99.66	AAK33487
FOPMFGFP_74	3862	2927	SP_0676	4.43e-170	transcription facot	81.73	96.89	AAK74821
FOPMFGFP_65	3129	3986	metF	5.31e-167	methionine biosynthesis enzymes	86.36	99.31	AAK74739
FOPMFGFP_97	29337	28633	covR	6.74e-133	responder protein	85.53	100.00	AAK71319
FOPMFGFP_102	3538	2867	rr01	9.95e-131	response regulator	84.38	99.56	CAB54566
FOPMFGFP_97	29337	28633	walR	9.06e-123	DNA-binding response regulator	81.28	100.00	ANC99504
FOPMFGFP_31	58400	59086	CovR	3.49e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
FOPMFGFP_6	15379	15774	SpxA2	3.22e-76	transcriptional regulator	90.91	100.00	ERL21461
FOPMFGFP_83	13984	14385	SpxA1	5.57e-68	transcriptional regulator	80.60	100.00	ERL19273
FOPMFGFP_35	13033	13320	spr0479	1.43e-49	essential gene	86.46	98.97	AAK99283
FOPMFGFP_43	33466	33720	spr1327	7.14e-46	essential gene	95.29	100.00	AAL00131
FOPMFGFP_141	2361	2624	spr0175	3.78e-43	pathogenitcity related	84.09	100.00	AAK98979
FOPMFGFP_141	3164	3454	spr0177	2.21e-38	essential gene	81.00	98.02	AAK98981
FOPMFGFP_25	6670	7170	RopE (M5005_Spy_1611)	9.93e-77	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
FOPMFGFP_126	2196	4493	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.68	98.08	MYN69560
FOPMFGFP_137	57314	56295	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451