Genome ID：GCA_000335515.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	16	32	35.78

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HLOKCMLO_91	13850	14443	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HLOKCMLO_91	13850	14443	STER_RS06030	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
HLOKCMLO_91	13850	14443	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
HLOKCMLO_74	799	2457	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
HLOKCMLO_91	14443	15312	rfbA	0.0	Capsule	Immune modulation	99.19	100.00	WP_011681286
HLOKCMLO_91	49211	49972	srtA	0.0	Sortase A	Exoenzyme	98.42	100.00	-
HLOKCMLO_90	18760	19554	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.11	100.25	-
HLOKCMLO_85	2695	3426	STER_RS05315	0.0	Capsule	Immune modulation	97.95	100.00	WP_011681176
HLOKCMLO_36	6628	7590	cbpD	0.0	Autolysin	Exoenzyme	97.73	99.90	WP_082302295
HLOKCMLO_85	1244	1984	STU_RS14635	0.0	Capsule	Immune modulation	97.71	100.00	WP_011226046
HLOKCMLO_85	2695	3426	STU_RS14645	0.0	Capsule	Immune modulation	97.68	100.00	WP_011226048
HLOKCMLO_85	2695	3426	STR_RS05260	0.0	Capsule	Immune modulation	97.27	100.00	WP_011227248
HLOKCMLO_111	7	858	rfbD	0.0	Capsule	Immune modulation	97.07	100.00	WP_014621820
HLOKCMLO_85	1244	1984	STER_RS05305	0.0	Capsule	Immune modulation	97.03	100.00	WP_011681174
HLOKCMLO_85	3427	4887	STER_RS05320	0.0	Capsule	Immune modulation	96.65	100.00	WP_011681177
HLOKCMLO_85	1249	1984	STR_RS05250	0.0	Capsule	Immune modulation	96.47	98.13	WP_011227246
HLOKCMLO_85	3427	4887	STU_RS14650	0.0	Capsule	Immune modulation	96.44	100.21	WP_011226049
HLOKCMLO_85	1994	2686	STR_RS05255	0.0	Capsule	Immune modulation	96.10	100.00	WP_011227247
HLOKCMLO_85	1994	2686	STU_RS14640	0.0	Capsule	Immune modulation	96.10	100.00	WP_011226047
HLOKCMLO_85	3427	4887	STR_RS05265	0.0	Capsule	Immune modulation	95.76	100.21	WP_041827043
HLOKCMLO_85	1	1187	STU_RS14630	0.0	Capsule	Immune modulation	94.52	86.77	WP_011226045
HLOKCMLO_85	1	1187	STER_RS05300	0.0	Capsule	Immune modulation	94.36	86.77	WP_011681173
HLOKCMLO_85	1994	2686	STER_RS05310	0.0	Capsule	Immune modulation	89.75	100.00	WP_011681175
HLOKCMLO_45	47041	48344	eno	0.0	Streptococcal enolase	Exoenzyme	88.09	99.54	WP_000022832
HLOKCMLO_129	631	1641	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.69	99.70	WP_002986042
HLOKCMLO_91	12375	13421	rfbB	0.0	Capsule	Immune modulation	80.71	100.00	WP_009659423
HLOKCMLO_16	5241	6524	tig/ropA	0.0	Trigger factor	Stress survival	80.50	99.77	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HLOKCMLO_91	52659	53642	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.51	100.00	AAK75326
HLOKCMLO_56	24273	25346	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
HLOKCMLO_123	35442	37745	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
HLOKCMLO_42	1881	2849	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
HLOKCMLO_102	4332	5813	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
HLOKCMLO_57	5612	7858	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
HLOKCMLO_6	12168	13160	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
HLOKCMLO_3	4132	5103	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
HLOKCMLO_116	16990	15839	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
HLOKCMLO_114	10735	8747	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
HLOKCMLO_91	36461	34731	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.69	100.00	AAK34199
HLOKCMLO_142	25796	24318	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
HLOKCMLO_45	47041	48342	Eno	0.0	enolase	86.44	99.77	ABP90468
HLOKCMLO_142	11059	9167	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
HLOKCMLO_57	10783	9074	PGM	0.0	phosphoglucomutase	83.36	99.65	ACH87041
HLOKCMLO_131	21509	22519	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
HLOKCMLO_76	2630	1269	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
HLOKCMLO_133	4816	2924	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
HLOKCMLO_45	32603	33493	bglB	4.47e-180	putative phospho--glucosidase	88.89	99.66	AAK33487
HLOKCMLO_64	3890	2955	SP_0676	4.44e-170	transcription facot	81.73	96.89	AAK74821
HLOKCMLO_57	8050	8907	metF	7.61e-167	methionine biosynthesis enzymes	86.36	99.31	AAK74739
HLOKCMLO_88	24434	23730	covR	5.85e-133	responder protein	85.53	100.00	AAK71319
HLOKCMLO_96	3521	2850	rr01	7.42e-131	response regulator	84.38	99.56	CAB54566
HLOKCMLO_88	24434	23730	walR	7.87e-123	DNA-binding response regulator	81.28	100.00	ANC99504
HLOKCMLO_26	6787	7473	CovR	6.91e-120	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
HLOKCMLO_6	13457	13852	SpxA2	2.84e-76	transcriptional regulator	90.91	100.00	ERL21461
HLOKCMLO_76	13987	14388	SpxA1	4.88e-68	transcriptional regulator	80.60	100.00	ERL19273
HLOKCMLO_29	13031	13318	spr0479	1.43e-49	essential gene	86.46	98.97	AAK99283
HLOKCMLO_37	33471	33725	spr1327	7.14e-46	essential gene	95.29	100.00	AAL00131
HLOKCMLO_138	2361	2624	spr0175	3.78e-43	pathogenitcity related	84.09	100.00	AAK98979
HLOKCMLO_138	3164	3454	spr0177	2.21e-38	essential gene	81.00	98.02	AAK98981
HLOKCMLO_16	6682	7182	RopE (M5005_Spy_1611)	9.94e-77	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
HLOKCMLO_123	35442	37739	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.68	98.08	MYN69560
HLOKCMLO_132	33890	32871	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451