Genome ID：GCA_000714445.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	15	38	40.90

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
KMMCNEJI_4	114523	115740	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
KMMCNEJI_4	115860	117323	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
KMMCNEJI_4	114523	115737	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
KMMCNEJI_4	115860	117320	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KMMCNEJI_4	47466	48831	STER_RS05300	0.0	Capsule	Immune modulation	95.24	99.85	WP_011681173
KMMCNEJI_4	47466	48833	STU_RS14630	0.0	Capsule	Immune modulation	94.30	100.00	WP_011226045
KMMCNEJI_4	43766	45226	STU_RS14650	0.0	Capsule	Immune modulation	94.18	100.14	WP_011226049
KMMCNEJI_6	77862	78908	rfbB	0.0	Capsule	Immune modulation	94.17	100.00	WP_002947383
KMMCNEJI_4	43766	45226	STER_RS05320	0.0	Capsule	Immune modulation	94.05	100.00	WP_011681177
KMMCNEJI_4	46669	47409	STER_RS05305	0.0	Capsule	Immune modulation	93.79	100.00	WP_011681174
KMMCNEJI_4	43766	45226	STR_RS05265	0.0	Capsule	Immune modulation	93.29	100.14	WP_041827043
KMMCNEJI_4	46669	47409	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
KMMCNEJI_4	45227	45958	STU_RS14645	0.0	Capsule	Immune modulation	92.62	100.00	WP_011226048
KMMCNEJI_6	77066	77659	STR_RS05880	0.0	Capsule	Immune modulation	92.59	100.00	WP_011226149
KMMCNEJI_4	46669	47404	STR_RS05250	0.0	Capsule	Immune modulation	92.53	98.13	WP_011227246
KMMCNEJI_4	45227	45958	STER_RS05315	0.0	Capsule	Immune modulation	92.49	100.00	WP_011681176
KMMCNEJI_6	77066	77659	STER_RS06030	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
KMMCNEJI_6	77066	77659	STU_RS15260	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
KMMCNEJI_25	86304	87154	rfbD	0.0	Capsule	Immune modulation	92.01	99.88	WP_014621820
KMMCNEJI_4	45227	45958	STR_RS05260	0.0	Capsule	Immune modulation	91.67	100.00	WP_011227248
KMMCNEJI_6	76197	77066	rfbA	0.0	Capsule	Immune modulation	91.15	100.00	WP_011681286
KMMCNEJI_26	73844	75502	fbp54	0.0	FBPs	Adherence	91.08	99.94	WP_011227179
KMMCNEJI_4	45967	46659	STR_RS05255	0.0	Capsule	Immune modulation	88.92	99.71	WP_011227247
KMMCNEJI_4	45967	46659	STU_RS14640	0.0	Capsule	Immune modulation	88.92	99.71	WP_011226047
KMMCNEJI_23	14247	15257	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
KMMCNEJI_33	90517	91820	eno	0.0	Streptococcal enolase	Exoenzyme	88.40	99.54	WP_000022832
KMMCNEJI_2	5363	6268	cbpD	0.0	Autolysin	Exoenzyme	88.30	93.50	WP_082302295
KMMCNEJI_4	45967	46659	STER_RS05310	0.0	Capsule	Immune modulation	87.05	99.71	WP_011681175
KMMCNEJI_5	53435	54196	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
KMMCNEJI_43	2155	3438	tig/ropA	0.0	Trigger factor	Stress survival	80.93	99.53	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KMMCNEJI_5	62327	63400	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
KMMCNEJI_5	50747	49773	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
KMMCNEJI_19	36920	39226	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
KMMCNEJI_15	74946	76427	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
KMMCNEJI_14	74514	75482	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
KMMCNEJI_5	81871	84117	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
KMMCNEJI_35	15376	14405	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
KMMCNEJI_15	6998	435	PrtA	0.0	serine protease	90.05	101.96	ABJ55268
KMMCNEJI_6	49330	51060	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.78	100.00	AAK34199
KMMCNEJI_24	63396	64547	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
KMMCNEJI_24	92142	94130	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
KMMCNEJI_17	29704	28226	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
KMMCNEJI_33	91820	90519	Eno	0.0	enolase	86.44	99.77	ABP90468
KMMCNEJI_17	13928	12036	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
KMMCNEJI_5	87039	85330	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
KMMCNEJI_32	2075	984	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KMMCNEJI_10	24064	23054	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
KMMCNEJI_26	89277	87916	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
KMMCNEJI_33	106230	105340	bglB	1.58e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
KMMCNEJI_26	12858	11908	SP_0676	3.33e-170	transcription facot	81.39	98.45	AAK74821
KMMCNEJI_5	84307	85164	metF	4.92e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
KMMCNEJI_25	87154	86315	GacA	6.49e-151	dTDP-4-dehydrorhamnose reductas	80.00	98.59	AAZ51220
KMMCNEJI_11	114545	115225	NisR	1.57e-131	two-component signal-transduction systems	93.83	100.00	ABP89873
KMMCNEJI_11	115213	115917	NisK	8.06e-131	two-component signal-transduction systems	90.64	100.00	ABP89872
KMMCNEJI_15	25107	24436	rr01	3.74e-127	response regulator	84.82	99.56	CAB54566
KMMCNEJI_4	1764	2468	covR	2.07e-126	responder protein	85.11	100.00	AAK71319
KMMCNEJI_5	91777	92448	ciaR	1.09e-125	two component system response regulator	86.16	99.12	AIK75708
KMMCNEJI_5	91777	92445	CiaR	2.01e-125	two-component response regulator	87.44	99.55	AAK74935
KMMCNEJI_4	1764	2468	walR	3.79e-120	DNA-binding response regulator	81.70	100.00	ANC99504
KMMCNEJI_1	147314	148000	CovR	4.39e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
KMMCNEJI_32	811	416	SpxA2	2.18e-76	transcriptional regulator	91.67	100.00	ERL21461
KMMCNEJI_26	100744	101145	SpxA1	1.30e-69	transcriptional regulator	82.09	100.00	ERL19273
KMMCNEJI_34	26058	26471	GrpE	5.90e-68	protein grpE	81.16	80.59	ABP89267
KMMCNEJI_1	170483	170770	spr0479	4.25e-48	essential gene	85.42	98.97	AAK99283
KMMCNEJI_14	31742	31996	spr1327	3.22e-44	essential gene	90.59	100.00	AAL00131
KMMCNEJI_7	38263	38000	spr0175	3.56e-43	pathogenitcity related	85.23	100.00	AAK98979
KMMCNEJI_7	37439	37173	spr0177	7.90e-42	essential gene	83.15	88.12	AAK98981
KMMCNEJI_11	24045	24182	srtA	2.25e-17	sortase	82.61	100.00	AAK33966
KMMCNEJI_43	3605	4096	RopE (M5005_Spy_1611)	4.21e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
KMMCNEJI_19	36920	39220	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
KMMCNEJI_40	22080	23099	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451