Genome ID：GCA_000714455.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	15	38	40.90

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
OHFMEFNL_15	114528	115745	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
OHFMEFNL_15	115865	117328	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
OHFMEFNL_15	114528	115742	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
OHFMEFNL_15	115865	117325	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
OHFMEFNL_15	47471	48836	STER_RS05300	0.0	Capsule	Immune modulation	95.24	99.85	WP_011681173
OHFMEFNL_15	47471	48838	STU_RS14630	0.0	Capsule	Immune modulation	94.30	100.00	WP_011226045
OHFMEFNL_15	43771	45231	STU_RS14650	0.0	Capsule	Immune modulation	94.18	100.14	WP_011226049
OHFMEFNL_29	77867	78913	rfbB	0.0	Capsule	Immune modulation	94.17	100.00	WP_002947383
OHFMEFNL_15	43771	45231	STER_RS05320	0.0	Capsule	Immune modulation	94.05	100.00	WP_011681177
OHFMEFNL_15	46674	47414	STER_RS05305	0.0	Capsule	Immune modulation	93.79	100.00	WP_011681174
OHFMEFNL_15	43771	45231	STR_RS05265	0.0	Capsule	Immune modulation	93.29	100.14	WP_041827043
OHFMEFNL_15	46674	47414	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
OHFMEFNL_15	45232	45963	STU_RS14645	0.0	Capsule	Immune modulation	92.62	100.00	WP_011226048
OHFMEFNL_29	77071	77664	STR_RS05880	0.0	Capsule	Immune modulation	92.59	100.00	WP_011226149
OHFMEFNL_15	46674	47409	STR_RS05250	0.0	Capsule	Immune modulation	92.53	98.13	WP_011227246
OHFMEFNL_15	45232	45963	STER_RS05315	0.0	Capsule	Immune modulation	92.49	100.00	WP_011681176
OHFMEFNL_29	77071	77664	STER_RS06030	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
OHFMEFNL_29	77071	77664	STU_RS15260	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
OHFMEFNL_24	604	1454	rfbD	0.0	Capsule	Immune modulation	92.01	99.88	WP_014621820
OHFMEFNL_15	45232	45963	STR_RS05260	0.0	Capsule	Immune modulation	91.67	100.00	WP_011227248
OHFMEFNL_29	76202	77071	rfbA	0.0	Capsule	Immune modulation	91.15	100.00	WP_011681286
OHFMEFNL_19	188037	189695	fbp54	0.0	FBPs	Adherence	91.08	99.94	WP_011227179
OHFMEFNL_15	45972	46664	STR_RS05255	0.0	Capsule	Immune modulation	88.92	99.71	WP_011227247
OHFMEFNL_15	45972	46664	STU_RS14640	0.0	Capsule	Immune modulation	88.92	99.71	WP_011226047
OHFMEFNL_10	14252	15262	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
OHFMEFNL_34	22215	23518	eno	0.0	Streptococcal enolase	Exoenzyme	88.40	99.54	WP_000022832
OHFMEFNL_12	5368	6273	cbpD	0.0	Autolysin	Exoenzyme	88.30	93.50	WP_082302295
OHFMEFNL_15	45972	46664	STER_RS05310	0.0	Capsule	Immune modulation	87.05	99.71	WP_011681175
OHFMEFNL_19	53442	54203	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
OHFMEFNL_42	2160	3443	tig/ropA	0.0	Trigger factor	Stress survival	80.93	99.53	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
OHFMEFNL_19	62334	63407	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
OHFMEFNL_19	50754	49780	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
OHFMEFNL_2	37152	39458	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
OHFMEFNL_1	105333	103852	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
OHFMEFNL_7	69602	68634	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
OHFMEFNL_19	81878	84124	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
OHFMEFNL_23	3940	4911	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
OHFMEFNL_1	173281	179844	PrtA	0.0	serine protease	90.05	101.96	ABJ55268
OHFMEFNL_29	49335	51065	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.78	100.00	AAK34199
OHFMEFNL_14	63401	64552	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
OHFMEFNL_14	92147	94135	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
OHFMEFNL_22	29709	28231	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
OHFMEFNL_34	22215	23516	Eno	0.0	enolase	86.44	99.77	ABP90468
OHFMEFNL_22	13933	12041	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
OHFMEFNL_19	87046	85337	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
OHFMEFNL_5	2080	989	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
OHFMEFNL_18	28643	29653	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
OHFMEFNL_19	203470	202109	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
OHFMEFNL_34	7805	8695	bglB	1.58e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
OHFMEFNL_19	127051	126101	SP_0676	5.33e-170	transcription facot	81.39	98.45	AAK74821
OHFMEFNL_19	84314	85171	metF	1.00e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
OHFMEFNL_24	604	1443	GacA	6.49e-151	dTDP-4-dehydrorhamnose reductas	80.00	98.59	AAZ51220
OHFMEFNL_3	114550	115230	NisR	1.57e-131	two-component signal-transduction systems	93.83	100.00	ABP89873
OHFMEFNL_3	115218	115922	NisK	8.06e-131	two-component signal-transduction systems	90.64	100.00	ABP89872
OHFMEFNL_1	155172	155843	rr01	3.79e-127	response regulator	84.82	99.56	CAB54566
OHFMEFNL_15	1769	2473	covR	2.07e-126	responder protein	85.11	100.00	AAK71319
OHFMEFNL_19	91783	92454	ciaR	2.22e-125	two component system response regulator	86.16	99.12	AIK75708
OHFMEFNL_19	91783	92451	CiaR	4.10e-125	two-component response regulator	87.44	99.55	AAK74935
OHFMEFNL_15	1769	2473	walR	3.79e-120	DNA-binding response regulator	81.70	100.00	ANC99504
OHFMEFNL_8	53685	52999	CovR	4.39e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
OHFMEFNL_5	816	421	SpxA2	2.18e-76	transcriptional regulator	91.67	100.00	ERL21461
OHFMEFNL_19	214937	215338	SpxA1	2.56e-69	transcriptional regulator	82.09	100.00	ERL19273
OHFMEFNL_6	6280	5867	GrpE	5.90e-68	protein grpE	81.16	80.59	ABP89267
OHFMEFNL_8	30516	30229	spr0479	4.25e-48	essential gene	85.42	98.97	AAK99283
OHFMEFNL_7	112374	112120	spr1327	3.22e-44	essential gene	90.59	100.00	AAL00131
OHFMEFNL_17	38268	38005	spr0175	3.56e-43	pathogenitcity related	85.23	100.00	AAK98979
OHFMEFNL_17	37444	37178	spr0177	7.91e-42	essential gene	83.15	88.12	AAK98981
OHFMEFNL_3	24050	24187	srtA	2.25e-17	sortase	82.61	100.00	AAK33966
OHFMEFNL_42	3610	4101	RopE (M5005_Spy_1611)	4.17e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
OHFMEFNL_2	37152	39452	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
OHFMEFNL_25	22085	23104	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451