Genome ID：GCA_002796635.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	23	31	38.61

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
DIHAIPFB_48	866	2806	tet(S)	ARO:3000192	tet(S)	99.84	100.78	L09756.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
DIHAIPFB_48	866	2791	tet(S)	Doxycycline, Tetracycline, Minocycline	100.00	100.00	L09756

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
DIHAIPFB_48	869	2791	tet(S)	tetracycline resistance ribosomal protection protein Tet(S)	EXACTX	100.00	100.00	WP_000691722.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
DIHAIPFB_24	16522	17331	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
DIHAIPFB_11	121167	122310	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	99.65	100.00	-
DIHAIPFB_12	13082	14740	fbp54	0.0	FBPs	Adherence	99.34	100.00	WP_011227179
DIHAIPFB_25	11873	13333	STER_RS05320	0.0	Capsule	Immune modulation	99.25	100.00	WP_011681177
DIHAIPFB_24	15317	16522	STU_RS16240	0.0	Capsule	Immune modulation	99.25	100.00	WP_011226326
DIHAIPFB_24	18268	19416	STU_RS16255	0.0	Capsule	Immune modulation	99.22	100.00	WP_041828290
DIHAIPFB_24	17315	18271	STU_RS16250	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226328
DIHAIPFB_24	12463	14245	STU_RS16230	0.0	Capsule	Immune modulation	99.10	99.89	WP_011226325
DIHAIPFB_2	3529	4398	rfbA	0.0	Capsule	Immune modulation	99.08	100.00	WP_011681286
DIHAIPFB_18	399	1250	rfbD	0.0	Capsule	Immune modulation	99.06	100.00	WP_014621820
DIHAIPFB_24	14242	15297	STU_RS16235	0.0	Capsule	Immune modulation	99.05	100.00	WP_002948022
DIHAIPFB_2	2936	3529	STR_RS05880	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226149
DIHAIPFB_2	2936	3529	STER_RS06030	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
DIHAIPFB_2	2936	3529	STU_RS15260	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
DIHAIPFB_25	13334	14065	STER_RS05315	0.0	Capsule	Immune modulation	98.50	100.00	WP_011681176
DIHAIPFB_2	37490	38251	srtA	0.0	Sortase A	Exoenzyme	98.42	100.00	-
DIHAIPFB_36	10405	11244	cbpD	0.0	Autolysin	Exoenzyme	98.33	100.00	WP_011226733
DIHAIPFB_25	13334	14065	STU_RS14645	0.0	Capsule	Immune modulation	97.95	100.00	WP_011226048
DIHAIPFB_25	13334	14065	STR_RS05260	0.0	Capsule	Immune modulation	97.81	100.00	WP_011227248
DIHAIPFB_25	11873	13333	STU_RS14650	0.0	Capsule	Immune modulation	96.99	100.21	WP_011226049
DIHAIPFB_25	14776	15516	STER_RS05305	0.0	Capsule	Immune modulation	96.76	100.00	WP_011681174
DIHAIPFB_25	11873	13333	STR_RS05265	0.0	Capsule	Immune modulation	96.58	100.21	WP_041827043
DIHAIPFB_25	14776	15516	STU_RS14635	0.0	Capsule	Immune modulation	96.36	100.00	WP_011226046
DIHAIPFB_25	14776	15511	STR_RS05250	0.0	Capsule	Immune modulation	96.20	98.13	WP_011227246
DIHAIPFB_25	14074	14766	STU_RS14640	0.0	Capsule	Immune modulation	95.96	100.00	WP_011226047
DIHAIPFB_25	14074	14766	STR_RS05255	0.0	Capsule	Immune modulation	95.67	100.00	WP_011227247
DIHAIPFB_25	15573	16938	STER_RS05300	0.0	Capsule	Immune modulation	94.95	99.85	WP_011681173
DIHAIPFB_25	15573	16940	STU_RS14630	0.0	Capsule	Immune modulation	93.71	100.00	WP_011226045
DIHAIPFB_25	14074	14766	STER_RS05310	0.0	Capsule	Immune modulation	92.06	100.00	WP_011681175
DIHAIPFB_11	21572	22875	eno	0.0	Streptococcal enolase	Exoenzyme	88.02	99.46	WP_000022832
DIHAIPFB_28	253	1263	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.66	99.90	WP_002986042
DIHAIPFB_23	3363	4646	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
DIHAIPFB_2	1460	2506	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
DIHAIPFB_39	1471	2054	SPD_RS01775	1.10e-145	Capsule	Immune modulation	82.73	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
DIHAIPFB_7	24893	25966	MntE	0.0	manganese homeostasis	94.97	99.72	ABF32167
DIHAIPFB_2	40938	41921	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
DIHAIPFB_11	104887	103919	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
DIHAIPFB_22	165003	166484	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
DIHAIPFB_19	11730	9427	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.45	99.22	AAK74619
DIHAIPFB_20	19210	16964	metE	0.0	methionine biosynthesis enzymes	91.72	100.00	AAK74738
DIHAIPFB_31	1884	886	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
DIHAIPFB_29	116	1087	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
DIHAIPFB_17	21955	23106	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
DIHAIPFB_18	16191	14203	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
DIHAIPFB_2	25547	23817	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
DIHAIPFB_77	28370	29848	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
DIHAIPFB_11	22875	21574	Eno	0.0	enolase	85.98	99.77	ABP90468
DIHAIPFB_77	43569	45461	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
DIHAIPFB_20	14039	15748	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
DIHAIPFB_33	50286	51296	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
DIHAIPFB_5	34306	35667	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
DIHAIPFB_11	37305	36415	bglB	1.25e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
DIHAIPFB_1	46677	47615	SP_0676	6.00e-169	transcription facot	81.15	97.20	AAK74821
DIHAIPFB_20	16772	15915	metF	7.34e-167	methionine biosynthesis enzymes	86.36	99.31	AAK74739
DIHAIPFB_44	82402	83106	covR	2.57e-132	responder protein	85.53	100.00	AAK71319
DIHAIPFB_22	131212	130541	rr01	2.73e-126	response regulator	84.38	99.56	CAB54566
DIHAIPFB_20	10085	9417	CiaR	9.67e-126	two-component response regulator	87.44	99.55	AAK74935
DIHAIPFB_20	10085	9414	ciaR	8.81e-124	two component system response regulator	85.27	99.12	AIK75708
DIHAIPFB_44	82402	83106	walR	1.08e-122	DNA-binding response regulator	82.13	100.00	ANC99504
DIHAIPFB_3	7678	6992	CovR	7.19e-120	serves to repress GAS virulence factor-encoding genes	81.22	100.00	ACE75886
DIHAIPFB_31	610	215	SpxA2	2.50e-76	transcriptional regulator	90.91	100.00	ERL21461
DIHAIPFB_6	25417	25130	spr0479	1.18e-48	essential gene	84.38	98.97	AAK99283
DIHAIPFB_11	163740	163486	spr1327	2.61e-45	essential gene	95.29	100.00	AAL00131
DIHAIPFB_9	14574	14837	spr0175	1.80e-42	pathogenitcity related	84.09	100.00	AAK98979
DIHAIPFB_9	15401	15667	spr0177	3.18e-34	essential gene	84.27	88.12	AAK98981
DIHAIPFB_23	4804	5304	RopE (M5005_Spy_1611)	4.47e-77	probable DNA-directed RNA polymerase subunit delta	82.04	87.43	AAK34603
DIHAIPFB_19	11730	9433	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.42	98.08	MYN69560
DIHAIPFB_33	86147	85128	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451