Genome ID：GCA_002796655.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	28	33	43.29

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
BICEFGKB_54	270	1007	ErmB	ARO:3000375	ErmB	99.18	98.79	AF242872.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
BICEFGKB_54	270	1007	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	X72021

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
BICEFGKB_54	273	1007	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038795.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
BICEFGKB_44	83769	84578	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
BICEFGKB_22	149512	150204	STU_RS14640	0.0	Capsule	Immune modulation	99.71	100.00	WP_011226047
BICEFGKB_11	3718	4861	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	99.56	100.00	-
BICEFGKB_44	86855	88639	STU_RS16230	0.0	Capsule	Immune modulation	99.55	100.00	WP_011226325
BICEFGKB_23	5703	7361	fbp54	0.0	FBPs	Adherence	99.46	100.00	WP_011227179
BICEFGKB_12	20021	20860	cbpD	0.0	Autolysin	Exoenzyme	99.41	100.00	WP_011226733
BICEFGKB_44	82829	83785	STU_RS16250	0.0	Capsule	Immune modulation	99.37	100.00	WP_011226328
BICEFGKB_44	84578	85783	STU_RS16240	0.0	Capsule	Immune modulation	99.25	100.00	WP_011226326
BICEFGKB_44	85803	86858	STU_RS16235	0.0	Capsule	Immune modulation	99.15	100.00	WP_002948022
BICEFGKB_22	149512	150204	STR_RS05255	0.0	Capsule	Immune modulation	99.13	100.00	WP_011227247
BICEFGKB_8	42967	43836	rfbA	0.0	Capsule	Immune modulation	99.08	100.00	WP_011681286
BICEFGKB_8	43836	44429	STR_RS05880	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226149
BICEFGKB_8	43836	44429	STER_RS06030	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
BICEFGKB_8	43836	44429	STU_RS15260	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
BICEFGKB_44	79026	79988	STU_RS16260	0.0	Capsule	Immune modulation	98.65	95.25	WP_011226330
BICEFGKB_22	148772	149503	STER_RS05315	0.0	Capsule	Immune modulation	98.63	100.00	WP_011681176
BICEFGKB_44	81684	82832	STU_RS16255	0.0	Capsule	Immune modulation	98.61	100.00	WP_041828290
BICEFGKB_8	8318	9079	srtA	0.0	Sortase A	Exoenzyme	98.56	100.00	-
BICEFGKB_22	147311	148771	STER_RS05320	0.0	Capsule	Immune modulation	98.43	100.00	WP_011681177
BICEFGKB_22	148772	149503	STU_RS14645	0.0	Capsule	Immune modulation	98.36	100.00	WP_011226048
BICEFGKB_22	148772	149503	STR_RS05260	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227248
BICEFGKB_44	77752	79023	STU_RS16265	0.0	Capsule	Immune modulation	97.64	99.76	WP_011226331
BICEFGKB_22	147311	148771	STU_RS14650	0.0	Capsule	Immune modulation	97.12	100.21	WP_011226049
BICEFGKB_44	75798	76649	rfbD	0.0	Capsule	Immune modulation	96.83	100.00	WP_014621820
BICEFGKB_22	152638	153634	STU_RS14625*	0.0	Capsule	Immune modulation	96.79	100.00	-
BICEFGKB_22	147311	148771	STR_RS05265	0.0	Capsule	Immune modulation	96.17	100.21	WP_041827043
BICEFGKB_11	136869	141764	SAG_RS09105	0.0	Agglutinin receptor	Adherence	96.02	100.00	WP_000167699
BICEFGKB_11	136811	141764	SSU98_0978	0.0	Agglutinin receptor	Adherence	95.82	100.00	YP_001200536
BICEFGKB_11	136811	141764	SSU05_0965	0.0	Agglutinin receptor	Adherence	95.80	100.00	YP_001198331
BICEFGKB_22	151029	152394	STER_RS05300	0.0	Capsule	Immune modulation	94.73	99.85	WP_011681173
BICEFGKB_22	151029	152396	STU_RS14630	0.0	Capsule	Immune modulation	93.79	100.00	WP_011226045
BICEFGKB_22	150214	150972	STER_RS05305	0.0	Capsule	Immune modulation	93.54	100.94	WP_011681174
BICEFGKB_22	150214	150972	STU_RS14635	0.0	Capsule	Immune modulation	93.15	100.94	WP_011226046
BICEFGKB_22	150214	150967	STR_RS05250	0.0	Capsule	Immune modulation	92.84	99.07	WP_011227246
BICEFGKB_22	149512	150204	STER_RS05310	0.0	Capsule	Immune modulation	89.61	100.00	WP_011681175
BICEFGKB_11	102232	103535	eno	0.0	Streptococcal enolase	Exoenzyme	88.02	99.54	WP_000022832
BICEFGKB_21	8475	9485	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.86	99.90	WP_002986042
BICEFGKB_65	2815	4098	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
BICEFGKB_8	44859	45905	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423
BICEFGKB_22	153643	154092	STU_RS14620	2.50e-178	Capsule	Immune modulation	92.00	100.00	WP_011226042
BICEFGKB_39	2229	2812	SPD_RS01775	1.34e-152	Capsule	Immune modulation	83.42	96.20	WP_001819836
BICEFGKB_22	154092	154399	STU_RS14615	9.39e-148	Capsule	Immune modulation	97.73	63.37	WP_011226041

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
BICEFGKB_11	136833	141761	B9H01_RS04765	0.0	glucan-binding protein	96.59	100.00	AUS90958
BICEFGKB_67	27639	28712	MntE	0.0	manganese homeostasis	94.97	99.72	ABF32167
BICEFGKB_8	5631	4648	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
BICEFGKB_11	20222	21190	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
BICEFGKB_5	41034	43337	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.32	99.22	AAK74619
BICEFGKB_66	47096	45615	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
BICEFGKB_67	48162	50408	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
BICEFGKB_12	39654	40652	recA	0.0	DNA recombination and repair	90.99	85.82	AAL00560
BICEFGKB_12	3439	4410	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
BICEFGKB_44	21369	22520	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
BICEFGKB_44	62291	64279	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
BICEFGKB_8	21817	23547	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
BICEFGKB_3	27016	28494	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
BICEFGKB_11	102232	103533	Eno	0.0	enolase	85.98	99.77	ABP90468
BICEFGKB_3	42215	44107	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
BICEFGKB_67	53333	51624	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
BICEFGKB_22	77574	76564	pdh	0.0	pyruvate dehydrogenase	82.20	99.70	ABP91006
BICEFGKB_7	5959	4598	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
BICEFGKB_22	27276	29168	PepO	0.0	endopeptidase	80.35	100.00	ABF32980
BICEFGKB_11	87803	88693	bglB	1.18e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
BICEFGKB_1	44677	45615	SP_0676	1.65e-168	transcription facot	81.15	97.20	AAK74821
BICEFGKB_67	50600	51457	metF	5.74e-167	methionine biosynthesis enzymes	86.71	99.31	AAK74739
BICEFGKB_4	24596	23892	covR	1.26e-132	responder protein	85.53	100.00	AAK71319
BICEFGKB_55	58320	58991	rr01	1.42e-126	response regulator	84.38	99.56	CAB54566
BICEFGKB_67	57287	57955	CiaR	1.87e-125	two-component response regulator	87.44	99.55	AAK74935
BICEFGKB_67	57287	57958	ciaR	2.01e-123	two component system response regulator	85.27	99.12	AIK75708
BICEFGKB_4	24596	23892	walR	5.31e-123	DNA-binding response regulator	82.13	100.00	ANC99504
BICEFGKB_9	36476	37162	CovR	2.38e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
BICEFGKB_12	40928	41323	SpxA2	8.28e-76	transcriptional regulator	90.91	100.00	ERL21461
BICEFGKB_13	25523	25236	spr0479	1.26e-48	essential gene	84.38	98.97	AAK99283
BICEFGKB_10	10817	11071	spr1327	6.52e-46	essential gene	95.29	100.00	AAL00131
BICEFGKB_20	15541	15278	spr0175	1.12e-42	pathogenitcity related	84.09	100.00	AAK98979
BICEFGKB_20	14714	14448	spr0177	4.51e-34	essential gene	84.27	88.12	AAK98981
BICEFGKB_65	4256	4756	RopE (M5005_Spy_1611)	1.27e-76	probable DNA-directed RNA polymerase subunit delta	82.04	87.43	AAK34603
BICEFGKB_5	41058	43331	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.03	97.06	MYN69560
BICEFGKB_22	41714	42733	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451