Genome ID：GCA_002796705.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	25	32	40.62

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
LEPAOMKF_45	662	2602	tet(S)	ARO:3000192	tet(S)	99.84	100.78	L09756.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
LEPAOMKF_45	677	2602	tet(S)	Doxycycline, Tetracycline, Minocycline	100.00	100.00	L09756

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
LEPAOMKF_45	677	2599	tet(S)	tetracycline resistance ribosomal protection protein Tet(S)	EXACTX	100.00	100.00	WP_000691722.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
LEPAOMKF_2	53188	53997	STU_RS16245	0.0	Capsule	Immune modulation	99.75	100.00	WP_002948020
LEPAOMKF_11	120910	122053	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	99.65	100.00	-
LEPAOMKF_2	56274	58058	STU_RS16230	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226325
LEPAOMKF_65	13426	15084	fbp54	0.0	FBPs	Adherence	99.34	100.00	WP_011227179
LEPAOMKF_2	53997	55202	STU_RS16240	0.0	Capsule	Immune modulation	99.25	100.00	WP_011226326
LEPAOMKF_18	15095	16555	STER_RS05320	0.0	Capsule	Immune modulation	99.18	100.00	WP_011681177
LEPAOMKF_2	52248	53204	STU_RS16250	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226328
LEPAOMKF_6	42537	43130	STR_RS05880	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226149
LEPAOMKF_6	41668	42537	rfbA	0.0	Capsule	Immune modulation	98.97	100.00	WP_011681286
LEPAOMKF_2	55222	56277	STU_RS16235	0.0	Capsule	Immune modulation	98.86	100.00	WP_002948022
LEPAOMKF_6	42537	43130	STER_RS06030	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
LEPAOMKF_6	42537	43130	STU_RS15260	0.0	Capsule	Immune modulation	98.82	100.00	WP_011226149
LEPAOMKF_2	48445	49407	STU_RS16260	0.0	Capsule	Immune modulation	98.65	95.25	WP_011226330
LEPAOMKF_6	7813	8574	srtA	0.0	Sortase A	Exoenzyme	98.56	100.00	-
LEPAOMKF_2	51103	52251	STU_RS16255	0.0	Capsule	Immune modulation	98.52	100.00	WP_041828290
LEPAOMKF_18	16556	17287	STER_RS05315	0.0	Capsule	Immune modulation	98.50	100.00	WP_011681176
LEPAOMKF_2	45217	46068	rfbD	0.0	Capsule	Immune modulation	98.36	100.00	WP_014621820
LEPAOMKF_30	214	1053	cbpD	0.0	Autolysin	Exoenzyme	98.33	100.00	WP_011226733
LEPAOMKF_18	16556	17287	STU_RS14645	0.0	Capsule	Immune modulation	97.95	100.00	WP_011226048
LEPAOMKF_18	16556	17287	STR_RS05260	0.0	Capsule	Immune modulation	97.81	100.00	WP_011227248
LEPAOMKF_2	47171	48442	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
LEPAOMKF_18	15095	16555	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
LEPAOMKF_18	17998	18738	STER_RS05305	0.0	Capsule	Immune modulation	96.76	100.00	WP_011681174
LEPAOMKF_18	15095	16555	STR_RS05265	0.0	Capsule	Immune modulation	96.51	100.21	WP_041827043
LEPAOMKF_18	17998	18738	STU_RS14635	0.0	Capsule	Immune modulation	96.36	100.00	WP_011226046
LEPAOMKF_18	17998	18733	STR_RS05250	0.0	Capsule	Immune modulation	96.20	98.13	WP_011227246
LEPAOMKF_18	17296	17988	STU_RS14640	0.0	Capsule	Immune modulation	95.96	100.00	WP_011226047
LEPAOMKF_18	17296	17988	STR_RS05255	0.0	Capsule	Immune modulation	95.67	100.00	WP_011227247
LEPAOMKF_18	18795	20160	STER_RS05300	0.0	Capsule	Immune modulation	95.39	99.85	WP_011681173
LEPAOMKF_18	18795	20162	STU_RS14630	0.0	Capsule	Immune modulation	94.15	100.00	WP_011226045
LEPAOMKF_18	17296	17988	STER_RS05310	0.0	Capsule	Immune modulation	92.06	100.00	WP_011681175
LEPAOMKF_11	22228	23531	eno	0.0	Streptococcal enolase	Exoenzyme	88.02	99.54	WP_000022832
LEPAOMKF_23	378	1388	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.06	99.90	WP_002986042
LEPAOMKF_17	19155	20438	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
LEPAOMKF_6	43560	44606	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
LEPAOMKF_34	6642	7225	SPD_RS01775	1.15e-145	Capsule	Immune modulation	82.73	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
LEPAOMKF_63	69047	70120	MntE	0.0	manganese homeostasis	94.97	99.72	ABF32167
LEPAOMKF_6	5126	4143	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
LEPAOMKF_11	105546	104578	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
LEPAOMKF_27	6124	4643	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
LEPAOMKF_4	41028	43331	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.45	99.22	AAK74619
LEPAOMKF_15	19517	17271	metE	0.0	methionine biosynthesis enzymes	91.72	100.00	AAK74738
LEPAOMKF_29	1888	890	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
LEPAOMKF_64	15466	14495	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
LEPAOMKF_14	21713	22864	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
LEPAOMKF_2	31706	33694	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
LEPAOMKF_6	20519	22249	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
LEPAOMKF_62	62172	60694	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
LEPAOMKF_11	23531	22230	Eno	0.0	enolase	85.98	99.77	ABP90468
LEPAOMKF_62	46973	45081	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
LEPAOMKF_15	14346	16055	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
LEPAOMKF_22	80492	79482	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
LEPAOMKF_65	31484	30123	mnmE	0.0	central tRNA-modifying GTPase	81.58	99.56	ABP90420
LEPAOMKF_11	37960	37070	bglB	1.25e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
LEPAOMKF_1	14072	13134	SP_0676	7.70e-169	transcription facot	81.15	97.20	AAK74821
LEPAOMKF_15	17079	16222	metF	7.43e-167	methionine biosynthesis enzymes	86.36	99.31	AAK74739
LEPAOMKF_55	24413	23709	covR	2.27e-132	responder protein	85.53	100.00	AAK71319
LEPAOMKF_9	22892	22221	rr01	5.87e-126	response regulator	83.93	99.56	CAB54566
LEPAOMKF_15	10392	9724	CiaR	8.15e-126	two-component response regulator	87.44	99.55	AAK74935
LEPAOMKF_15	10392	9721	ciaR	8.75e-124	two component system response regulator	85.27	99.12	AIK75708
LEPAOMKF_55	24413	23709	walR	9.55e-123	DNA-binding response regulator	82.13	100.00	ANC99504
LEPAOMKF_7	7672	6986	CovR	7.19e-120	serves to repress GAS virulence factor-encoding genes	81.22	100.00	ACE75886
LEPAOMKF_29	614	219	SpxA2	2.49e-76	transcriptional regulator	90.91	100.00	ERL21461
LEPAOMKF_65	42969	43370	SpxA1	1.75e-67	transcriptional regulator	80.60	100.00	ERL19273
LEPAOMKF_64	55366	55079	spr0479	2.10e-48	essential gene	84.38	98.97	AAK99283
LEPAOMKF_11	163483	163229	spr1327	2.60e-45	essential gene	95.29	100.00	AAL00131
LEPAOMKF_10	18056	17793	spr0175	1.59e-42	pathogenitcity related	84.09	100.00	AAK98979
LEPAOMKF_10	17229	16963	spr0177	2.80e-34	essential gene	84.27	88.12	AAK98981
LEPAOMKF_17	18997	18497	RopE (M5005_Spy_1611)	4.44e-77	probable DNA-directed RNA polymerase subunit delta	82.04	87.43	AAK34603
LEPAOMKF_4	41052	43325	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.16	97.06	MYN69560
LEPAOMKF_22	44632	45651	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451