Genome ID：GCA_003458505.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	19	35	39.82

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HHFOALAE_23	77916	78631	STER_RS07085	0.0	Capsule	Immune modulation	96.65	99.86	WP_011681442
HHFOALAE_23	81940	82791	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
HHFOALAE_23	78633	79601	STER_RS07090	0.0	Capsule	Immune modulation	94.94	100.00	WP_011681443
HHFOALAE_29	23924	25384	STU_RS14650	0.0	Capsule	Immune modulation	94.32	100.14	WP_011226049
HHFOALAE_29	23924	25384	STER_RS05320	0.0	Capsule	Immune modulation	94.18	100.00	WP_011681177
HHFOALAE_29	23924	25384	STR_RS05265	0.0	Capsule	Immune modulation	93.43	100.14	WP_041827043
HHFOALAE_29	20318	21683	STER_RS05300	0.0	Capsule	Immune modulation	93.12	99.85	WP_011681173
HHFOALAE_29	20316	21683	STU_RS14630	0.0	Capsule	Immune modulation	92.98	100.00	WP_011226045
HHFOALAE_23	76794	77570	STER_RS07075	0.0	Capsule	Immune modulation	92.92	100.00	WP_011681440
HHFOALAE_23	80568	81821	STER_RS07100	0.0	Capsule	Immune modulation	92.34	99.44	WP_011681445
HHFOALAE_29	23192	23923	STU_RS14645	0.0	Capsule	Immune modulation	91.80	100.00	WP_011226048
HHFOALAE_12	172347	172940	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
HHFOALAE_12	172347	172940	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
HHFOALAE_12	172347	172940	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
HHFOALAE_29	23192	23923	STER_RS05315	0.0	Capsule	Immune modulation	91.39	100.00	WP_011681176
HHFOALAE_29	23192	23923	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
HHFOALAE_29	21741	22481	STER_RS05305	0.0	Capsule	Immune modulation	90.84	99.87	WP_011681174
HHFOALAE_28	95003	96661	fbp54	0.0	FBPs	Adherence	90.78	99.94	WP_011227179
HHFOALAE_12	171478	172347	rfbA	0.0	Capsule	Immune modulation	90.58	100.00	WP_011681286
HHFOALAE_29	21741	22481	STU_RS14635	0.0	Capsule	Immune modulation	89.89	99.87	WP_011226046
HHFOALAE_29	21746	22481	STR_RS05250	0.0	Capsule	Immune modulation	89.55	98.00	WP_011227246
HHFOALAE_27	154445	155455	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
HHFOALAE_1	184	1487	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
HHFOALAE_1	197033	197933	cbpD	0.0	Autolysin	Exoenzyme	88.23	92.98	WP_082302295
HHFOALAE_29	22491	23183	STR_RS05255	0.0	Capsule	Immune modulation	87.18	99.86	WP_011227247
HHFOALAE_29	22491	23183	STU_RS14640	0.0	Capsule	Immune modulation	87.18	99.86	WP_011226047
HHFOALAE_29	22491	23183	STER_RS05310	0.0	Capsule	Immune modulation	86.45	99.86	WP_011681175
HHFOALAE_31	70633	71394	srtA	0.0	Sortase A	Exoenzyme	84.67	99.87	-
HHFOALAE_12	173143	174189	rfbB	0.0	Capsule	Immune modulation	84.16	99.90	WP_002263087
HHFOALAE_14	8368	9651	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HHFOALAE_31	74083	75066	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
HHFOALAE_31	62498	61425	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
HHFOALAE_27	33971	36277	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
HHFOALAE_26	113094	114575	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
HHFOALAE_31	43440	41194	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
HHFOALAE_1	96730	95762	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
HHFOALAE_6	4745	5716	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
HHFOALAE_12	146095	147825	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
HHFOALAE_23	125219	124068	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HHFOALAE_23	96694	94706	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
HHFOALAE_8	25715	27193	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HHFOALAE_1	1487	186	Eno	0.0	enolase	86.44	99.77	ABP90468
HHFOALAE_1	452361	450469	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
HHFOALAE_31	38272	39981	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
HHFOALAE_6	41750	42841	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HHFOALAE_1	317756	318766	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
HHFOALAE_28	68974	70335	mnmE	0.0	central tRNA-modifying GTPase	83.33	99.56	ABP90420
HHFOALAE_1	15896	15006	bglB	2.67e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
HHFOALAE_13	11363	12313	SP_0676	1.46e-171	transcription facot	81.39	98.45	AAK74821
HHFOALAE_31	41004	40147	metF	6.42e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
HHFOALAE_28	121040	120255	pnuC	1.03e-150	NAD salvage pathway importer	87.41	97.40	AAK75931
HHFOALAE_26	48638	47967	rr01	3.89e-127	response regulator	84.82	99.56	CAB54566
HHFOALAE_29	71068	70364	covR	5.42e-127	responder protein	85.53	100.00	AAK71319
HHFOALAE_31	34305	33634	ciaR	8.51e-126	two component system response regulator	86.16	99.12	AIK75708
HHFOALAE_31	34305	33637	CiaR	1.57e-125	two-component response regulator	87.44	99.55	AAK74935
HHFOALAE_23	123290	122523	potC	3.70e-124	ABC transporter ATP-binding protein-spermidine/putrescine transport	80.08	99.61	AAL00048
HHFOALAE_29	71068	70364	walR	1.23e-120	DNA-binding response regulator	82.13	100.00	ANC99504
HHFOALAE_4	53617	52931	CovR	1.34e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
HHFOALAE_6	43016	43411	SpxA2	4.28e-76	transcriptional regulator	91.67	100.00	ERL21461
HHFOALAE_28	57506	57105	SpxA1	3.20e-70	transcriptional regulator	82.84	100.00	ERL19273
HHFOALAE_5	6809	6396	GrpE	3.74e-68	protein grpE	81.88	80.59	ABP89267
HHFOALAE_4	30409	30122	spr0479	1.54e-48	essential gene	85.42	98.97	AAK99283
HHFOALAE_1	140553	140299	spr1327	2.12e-44	essential gene	92.94	100.00	AAL00131
HHFOALAE_1	408824	409087	spr0175	2.41e-42	pathogenitcity related	85.23	100.00	AAK98979
HHFOALAE_1	409648	409914	spr0177	5.35e-41	essential gene	83.15	88.12	AAK98981
HHFOALAE_14	8201	7710	RopE (M5005_Spy_1611)	5.36e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HHFOALAE_27	33971	36271	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
HHFOALAE_1	354178	353159	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451