Genome ID：GCA_003458645.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	17	34	38.07

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
IGHDCBEA_34	94912	96831	tet(M)	ARO:3000186	tet(M)	99.37	100.00	AB039845.1
IGHDCBEA_34	93066	93803	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
IGHDCBEA_34	93066	93803	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
IGHDCBEA_34	94912	96831	tet(M)	Doxycycline, Tetracycline, Minocycline	99.74	100.00	X75073

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
IGHDCBEA_34	93069	93803	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
IGHDCBEA_34	94915	96831	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691727.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
IGHDCBEA_48	86455	87306	rfbD	0.0	Capsule	Immune modulation	95.42	100.00	WP_014621820
IGHDCBEA_16	1718	2449	STR_RS05260	0.0	Capsule	Immune modulation	94.40	100.00	WP_011227248
IGHDCBEA_16	1718	2449	STER_RS05315	0.0	Capsule	Immune modulation	93.99	100.00	WP_011681176
IGHDCBEA_16	1718	2449	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
IGHDCBEA_48	83317	84032	STER_RS07085	0.0	Capsule	Immune modulation	93.72	99.86	WP_011681442
IGHDCBEA_48	82201	82971	STER_RS07075	0.0	Capsule	Immune modulation	92.61	99.23	WP_011681440
IGHDCBEA_48	85078	86336	STER_RS07100	0.0	Capsule	Immune modulation	92.54	99.92	WP_011681445
IGHDCBEA_16	257	1717	STER_RS05320	0.0	Capsule	Immune modulation	91.33	99.86	WP_011681177
IGHDCBEA_45	45382	45975	STR_RS05880	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
IGHDCBEA_45	45382	45975	STER_RS06030	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
IGHDCBEA_45	45382	45975	STU_RS15260	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
IGHDCBEA_23	108041	109699	fbp54	0.0	FBPs	Adherence	91.02	99.94	WP_011227179
IGHDCBEA_16	257	1717	STU_RS14650	0.0	Capsule	Immune modulation	90.72	100.00	WP_011226049
IGHDCBEA_4	34446	35351	cbpD	0.0	Autolysin	Exoenzyme	90.07	93.50	WP_082302295
IGHDCBEA_16	2458	3150	STU_RS14640	0.0	Capsule	Immune modulation	90.04	100.00	WP_011226047
IGHDCBEA_16	257	1717	STR_RS05265	0.0	Capsule	Immune modulation	90.03	100.00	WP_041827043
IGHDCBEA_16	2458	3150	STR_RS05255	0.0	Capsule	Immune modulation	89.75	100.00	WP_011227247
IGHDCBEA_16	2458	3150	STER_RS05310	0.0	Capsule	Immune modulation	89.61	100.00	WP_011681175
IGHDCBEA_1	31860	33163	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
IGHDCBEA_1	477115	478128	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
IGHDCBEA_2	27516	28277	srtA	0.0	Sortase A	Exoenzyme	84.14	99.87	-
IGHDCBEA_25	5881	7164	tig/ropA	0.0	Trigger factor	Stress survival	80.53	99.61	WP_000107753
IGHDCBEA_45	46245	47291	rfbB	0.0	Capsule	Immune modulation	80.52	100.00	WP_009659423
IGHDCBEA_45	44513	45382	rfbA	0.0	Capsule	Immune modulation	80.16	99.77	WP_002904719
IGHDCBEA_16	3160	3830	STU_RS14635	4.98e-147	Capsule	Immune modulation	80.83	90.28	WP_011226046
IGHDCBEA_16	3160	3830	STER_RS05305	2.32e-145	Capsule	Immune modulation	80.68	90.28	WP_011681174

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
IGHDCBEA_2	30967	31950	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
IGHDCBEA_2	19377	18304	MntE	0.0	manganese homeostasis	95.81	99.72	ABF32167
IGHDCBEA_1	352541	354847	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
IGHDCBEA_34	83438	84919	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
IGHDCBEA_30	223	2469	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
IGHDCBEA_1	124702	123734	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
IGHDCBEA_29	1028	57	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
IGHDCBEA_45	10895	12625	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
IGHDCBEA_48	102675	100687	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
IGHDCBEA_1	214024	212873	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
IGHDCBEA_49	25678	27156	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
IGHDCBEA_1	33163	31862	Eno	0.0	enolase	86.44	99.77	ABP90468
IGHDCBEA_49	41019	42911	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
IGHDCBEA_18	11759	12850	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
IGHDCBEA_26	1824	115	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
IGHDCBEA_3	35589	34579	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
IGHDCBEA_23	123457	122096	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
IGHDCBEA_30	2658	3515	metF	2.03e-179	methionine biosynthesis enzymes	87.76	99.31	AAK74739
IGHDCBEA_1	47577	46687	bglB	5.34e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
IGHDCBEA_23	34713	33763	SP_0676	4.70e-171	transcription facot	81.39	98.45	AAK74821
IGHDCBEA_6	11656	10799	mtsA	1.10e-152	substrate-binding lipoprotein of manganese transporter	80.49	92.86	AIK76191
IGHDCBEA_20	303	1007	covR	4.89e-128	responder protein	85.53	100.00	AAK71319
IGHDCBEA_34	23470	22799	rr01	3.04e-127	response regulator	84.82	99.56	CAB54566
IGHDCBEA_26	6489	7160	ciaR	7.90e-127	two component system response regulator	86.16	99.12	AIK75708
IGHDCBEA_26	6489	7157	CiaR	1.46e-126	two-component response regulator	87.44	99.55	AAK74935
IGHDCBEA_20	303	1007	walR	1.11e-121	DNA-binding response regulator	82.13	100.00	ANC99504
IGHDCBEA_12	152594	153280	CovR	1.64e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
IGHDCBEA_43	156	551	SpxA2	9.27e-86	transcriptional regulator	91.67	100.00	ERL21461
IGHDCBEA_23	134922	135323	SpxA1	1.08e-69	transcriptional regulator	82.09	100.00	ERL19273
IGHDCBEA_51	72515	72928	GrpE	6.13e-68	protein grpE	81.88	80.59	ABP89267
IGHDCBEA_12	175784	176071	spr0479	5.19e-48	essential gene	85.42	98.97	AAK99283
IGHDCBEA_1	171715	171461	spr1327	2.26e-44	essential gene	92.94	100.00	AAL00131
IGHDCBEA_49	81728	81465	spr0175	4.91e-43	pathogenitcity related	85.23	100.00	AAK98979
IGHDCBEA_49	80904	80638	spr0177	1.09e-41	essential gene	83.15	88.12	AAK98981
IGHDCBEA_25	5714	5223	RopE (M5005_Spy_1611)	4.14e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
IGHDCBEA_1	352541	354841	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
IGHDCBEA_10	1580	561	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
IGHDCBEA_23	95057	95596	pnuC	9.55e-93	NAD salvage pathway importer	82.78	66.91	AAK75931