Genome ID：GCA_003465325.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	18	36	40.30

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
MIFDOENC_34	136216	136953	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1
MIFDOENC_34	133372	135291	tet(M)	ARO:3000186	tet(M)	99.06	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
MIFDOENC_34	136216	136953	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
MIFDOENC_34	133372	135291	tet(M)	Doxycycline, Tetracycline, Minocycline	99.53	100.00	X75073

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
MIFDOENC_34	136216	136950	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
MIFDOENC_34	133372	135288	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	99.84	100.00	WP_000691736.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
MIFDOENC_4	46984	47724	STER_RS05305	0.0	Capsule	Immune modulation	94.74	100.00	WP_011681174
MIFDOENC_34	38590	39440	rfbD	0.0	Capsule	Immune modulation	94.71	99.88	WP_014621820
MIFDOENC_34	42165	42881	STER_RS07085	0.0	Capsule	Immune modulation	94.56	100.00	WP_011681442
MIFDOENC_4	46984	47724	STU_RS14635	0.0	Capsule	Immune modulation	94.06	100.00	WP_011226046
MIFDOENC_4	45560	46927	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
MIFDOENC_4	49167	50627	STU_RS14650	0.0	Capsule	Immune modulation	93.91	100.14	WP_011226049
MIFDOENC_4	49167	50627	STER_RS05320	0.0	Capsule	Immune modulation	93.91	100.00	WP_011681177
MIFDOENC_4	45562	46927	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
MIFDOENC_4	46989	47724	STR_RS05250	0.0	Capsule	Immune modulation	93.48	98.13	WP_011227246
MIFDOENC_34	43227	43997	STER_RS07075	0.0	Capsule	Immune modulation	93.26	99.10	WP_011681440
MIFDOENC_4	49167	50627	STR_RS05265	0.0	Capsule	Immune modulation	93.16	100.14	WP_041827043
MIFDOENC_6	58937	60595	fbp54	0.0	FBPs	Adherence	91.39	99.94	WP_011227179
MIFDOENC_4	48435	49166	STU_RS14645	0.0	Capsule	Immune modulation	91.26	100.00	WP_011226048
MIFDOENC_4	48435	49166	STER_RS05315	0.0	Capsule	Immune modulation	90.98	100.00	WP_011681176
MIFDOENC_53	77917	78510	STR_RS05880	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
MIFDOENC_53	77917	78510	STER_RS06030	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
MIFDOENC_53	77917	78510	STU_RS15260	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
MIFDOENC_53	78510	79379	rfbA	0.0	Capsule	Immune modulation	90.58	100.00	WP_011681286
MIFDOENC_4	48435	49166	STR_RS05260	0.0	Capsule	Immune modulation	90.44	100.00	WP_011227248
MIFDOENC_20	18001	18762	cbpD	0.0	Autolysin	Exoenzyme	90.29	90.71	WP_011226733
MIFDOENC_5	59606	60616	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
MIFDOENC_23	43167	44470	eno	0.0	Streptococcal enolase	Exoenzyme	88.32	99.54	WP_000022832
MIFDOENC_4	47734	48426	STR_RS05255	0.0	Capsule	Immune modulation	87.61	99.86	WP_011227247
MIFDOENC_4	47734	48426	STU_RS14640	0.0	Capsule	Immune modulation	87.61	99.86	WP_011226047
MIFDOENC_4	47734	48426	STER_RS05310	0.0	Capsule	Immune modulation	86.45	99.86	WP_011681175
MIFDOENC_54	59102	59863	srtA	0.0	Sortase A	Exoenzyme	84.53	99.87	-
MIFDOENC_53	76599	77644	rfbB	0.0	Capsule	Immune modulation	84.16	99.81	WP_002263087
MIFDOENC_55	112658	113941	tig/ropA	0.0	Trigger factor	Stress survival	80.92	99.61	WP_000107753
MIFDOENC_4	35737	36320	SPD_RS01775	4.34e-163	Capsule	Immune modulation	84.61	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
MIFDOENC_54	62551	63534	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.34	100.00	AAK75326
MIFDOENC_54	50973	49900	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
MIFDOENC_1	65534	63228	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
MIFDOENC_23	134940	133972	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
MIFDOENC_2	14618	15994	SPD_0310	0.0	UPF0371 protein SPD_0310	93.03	92.91	ABJ54480
MIFDOENC_54	31427	29181	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
MIFDOENC_20	3581	4552	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
MIFDOENC_54	117166	112511	PrtA	0.0	serine protease	91.63	72.34	ABJ55268
MIFDOENC_53	104752	103022	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
MIFDOENC_1	206382	207533	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
MIFDOENC_34	26662	28650	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
MIFDOENC_23	44470	43169	Eno	0.0	enolase	86.44	99.77	ABP90468
MIFDOENC_12	41313	43205	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
MIFDOENC_12	25973	27430	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	85.60	98.58	ADE32434
MIFDOENC_54	26258	27967	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
MIFDOENC_19	2118	1027	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
MIFDOENC_6	45426	46787	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
MIFDOENC_16	28831	29841	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
MIFDOENC_23	58883	57993	bglB	1.55e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
MIFDOENC_56	74563	75513	SP_0676	1.19e-170	transcription facot	81.39	98.45	AAK74821
MIFDOENC_54	28990	28133	metF	5.99e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
MIFDOENC_21	2340	1669	NisR	3.75e-130	two-component signal-transduction systems	93.75	98.68	ABP89873
MIFDOENC_8	38462	39133	rr01	1.23e-127	response regulator	84.82	99.56	CAB54566
MIFDOENC_7	21079	20372	covR	6.77e-127	responder protein	86.44	100.00	AAK71319
MIFDOENC_54	22294	21623	ciaR	1.14e-125	two component system response regulator	86.16	99.12	AIK75708
MIFDOENC_54	22294	21626	CiaR	2.10e-125	two-component response regulator	87.44	99.55	AAK74935
MIFDOENC_7	21079	20372	walR	9.77e-121	DNA-binding response regulator	82.20	100.43	ANC99504
MIFDOENC_3	25360	26046	CovR	1.73e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
MIFDOENC_21	1681	1133	NisK	2.14e-107	two-component signal-transduction systems	90.71	77.87	ABP89872
MIFDOENC_19	854	459	SpxA2	2.19e-76	transcriptional regulator	91.67	100.00	ERL21461
MIFDOENC_6	33961	33560	SpxA1	1.37e-70	transcriptional regulator	82.84	100.00	ERL19273
MIFDOENC_9	41086	41499	GrpE	3.71e-68	protein grpE	81.88	80.59	ABP89267
MIFDOENC_3	48573	48860	spr0479	1.68e-48	essential gene	85.42	98.97	AAK99283
MIFDOENC_23	169862	169608	spr1327	8.03e-45	essential gene	92.94	100.00	AAL00131
MIFDOENC_12	83072	82809	spr0175	9.54e-43	pathogenitcity related	85.23	100.00	AAK98979
MIFDOENC_12	82248	81982	spr0177	2.12e-41	essential gene	83.15	88.12	AAK98981
MIFDOENC_55	112491	112000	RopE (M5005_Spy_1611)	5.60e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
MIFDOENC_1	65534	63234	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
MIFDOENC_12	140148	141167	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451