Genome ID：GCA_003465885.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	34	39.50

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
AJHLEFAA_3	38606	39343	ErmB	ARO:3000375	ErmB	98.78	98.79	AF242872.1
AJHLEFAA_3	35580	37499	tet(M)	ARO:3000186	tet(M)	98.90	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
AJHLEFAA_3	38606	39343	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.86	100.00	JN899585
AJHLEFAA_3	35580	37499	tet(M)	Doxycycline, Tetracycline, Minocycline	99.84	100.00	X92947

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
AJHLEFAA_3	35580	37496	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691736.1
AJHLEFAA_3	38606	39340	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	BLASTX	99.59	100.00	WP_001038795.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
AJHLEFAA_49	94319	95170	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
AJHLEFAA_3	17702	18433	STR_RS05260	0.0	Capsule	Immune modulation	94.40	100.00	WP_011227248
AJHLEFAA_3	17702	18433	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
AJHLEFAA_3	17702	18433	STER_RS05315	0.0	Capsule	Immune modulation	93.44	100.00	WP_011681176
AJHLEFAA_49	87298	89054	STU_RS16230	0.0	Capsule	Immune modulation	92.60	98.43	WP_011226325
AJHLEFAA_49	92115	93071	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
AJHLEFAA_49	90117	91322	STU_RS16240	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226326
AJHLEFAA_49	91322	92131	STU_RS16245	0.0	Capsule	Immune modulation	92.36	99.88	WP_002948020
AJHLEFAA_49	93068	94216	STU_RS16255	0.0	Capsule	Immune modulation	91.74	99.91	WP_041828290
AJHLEFAA_3	18434	19894	STER_RS05320	0.0	Capsule	Immune modulation	91.26	99.86	WP_011681177
AJHLEFAA_49	89051	90097	STU_RS16235	0.0	Capsule	Immune modulation	91.19	99.43	WP_002948022
AJHLEFAA_34	32213	32806	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
AJHLEFAA_45	21515	23173	fbp54	0.0	FBPs	Adherence	90.96	99.94	WP_011227179
AJHLEFAA_34	32213	32806	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
AJHLEFAA_34	32213	32806	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
AJHLEFAA_3	18434	19894	STU_RS14650	0.0	Capsule	Immune modulation	90.65	100.00	WP_011226049
AJHLEFAA_10	10156	11061	cbpD	0.0	Autolysin	Exoenzyme	90.07	93.50	WP_082302295
AJHLEFAA_3	18434	19894	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
AJHLEFAA_3	17001	17693	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
AJHLEFAA_3	17001	17693	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
AJHLEFAA_3	17001	17693	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
AJHLEFAA_12	158419	159722	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
AJHLEFAA_1	70293	71306	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
AJHLEFAA_11	32381	33142	srtA	0.0	Sortase A	Exoenzyme	83.88	99.87	-
AJHLEFAA_34	30897	31943	rfbB	0.0	Capsule	Immune modulation	83.49	99.90	WP_002263087
AJHLEFAA_16	24286	25569	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
AJHLEFAA_34	32806	33675	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
AJHLEFAA_3	16321	16991	STU_RS14635	3.48e-148	Capsule	Immune modulation	80.98	90.28	WP_011226046
AJHLEFAA_3	16321	16991	STER_RS05305	1.62e-146	Capsule	Immune modulation	80.83	90.28	WP_011681174
AJHLEFAA_3	16389	16991	STR_RS05250	1.64e-136	Capsule	Immune modulation	81.46	80.13	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
AJHLEFAA_11	35832	36815	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
AJHLEFAA_11	24244	23171	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
AJHLEFAA_13	22288	24594	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
AJHLEFAA_23	115763	117244	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
AJHLEFAA_11	4705	2459	metE	0.0	methionine biosynthesis enzymes	93.06	100.00	AAK74738
AJHLEFAA_12	70537	71505	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
AJHLEFAA_14	4540	5511	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
AJHLEFAA_23	52222	45749	PrtA	0.0	serine protease	91.39	100.61	ABJ55268
AJHLEFAA_34	59052	57322	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
AJHLEFAA_49	107589	105601	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
AJHLEFAA_9	30652	31803	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
AJHLEFAA_50	25712	27190	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
AJHLEFAA_12	158419	159720	Eno	0.0	enolase	86.44	99.77	ABP90468
AJHLEFAA_50	41062	42954	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
AJHLEFAA_24	6586	7677	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
AJHLEFAA_45	147333	149042	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
AJHLEFAA_51	59240	58230	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
AJHLEFAA_45	5795	7156	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
AJHLEFAA_12	144005	144895	bglB	2.55e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
AJHLEFAA_45	105921	106871	SP_0676	1.64e-170	transcription facot	81.39	98.45	AAK74821
AJHLEFAA_11	2269	1412	metF	1.58e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
AJHLEFAA_28	1907	2611	covR	1.29e-128	responder protein	85.53	100.00	AAK71319
AJHLEFAA_23	70359	69688	rr01	2.80e-127	response regulator	85.27	99.56	CAB54566
AJHLEFAA_45	142668	141997	ciaR	1.43e-125	two component system response regulator	86.16	99.12	AIK75708
AJHLEFAA_45	142668	142000	CiaR	2.64e-125	two-component response regulator	87.44	99.55	AAK74935
AJHLEFAA_28	1907	2611	walR	3.84e-122	DNA-binding response regulator	82.13	100.00	ANC99504
AJHLEFAA_1	144404	143718	CovR	2.25e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
AJHLEFAA_24	7850	8245	SpxA2	8.14e-77	transcriptional regulator	91.67	100.00	ERL21461
AJHLEFAA_52	52324	51923	SpxA1	4.25e-70	transcriptional regulator	82.09	100.00	ERL19273
AJHLEFAA_2	58522	58935	GrpE	5.29e-69	protein grpE	82.61	80.59	ABP89267
AJHLEFAA_1	121199	120912	spr0479	7.09e-48	essential gene	85.42	98.97	AAK99283
AJHLEFAA_12	31550	31804	spr1327	2.62e-46	essential gene	96.47	100.00	AAL00131
AJHLEFAA_50	91195	90932	spr0175	5.36e-43	pathogenitcity related	85.23	100.00	AAK98979
AJHLEFAA_50	90370	90104	spr0177	1.19e-41	essential gene	83.15	88.12	AAK98981
AJHLEFAA_16	24119	23628	RopE (M5005_Spy_1611)	1.31e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
AJHLEFAA_13	22288	24588	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
AJHLEFAA_51	23366	24385	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451