Genome ID：GCA_004166915.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	23	33	40.27

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
KNDMLKOK_2	33473	34936	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
KNDMLKOK_2	35056	36273	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
KNDMLKOK_2	35059	36273	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
KNDMLKOK_2	33476	34936	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KNDMLKOK_1	73923	74774	rfbD	0.0	Capsule	Immune modulation	95.19	100.00	WP_014621820
KNDMLKOK_4	57710	58450	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
KNDMLKOK_4	57710	58450	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
KNDMLKOK_4	54807	56267	STU_RS14650	0.0	Capsule	Immune modulation	94.11	100.14	WP_011226049
KNDMLKOK_4	54807	56267	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
KNDMLKOK_4	58507	59874	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
KNDMLKOK_4	57710	58445	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
KNDMLKOK_4	58507	59872	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
KNDMLKOK_1	71551	72822	STU_RS16265	0.0	Capsule	Immune modulation	93.47	99.76	WP_011226331
KNDMLKOK_4	54807	56267	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
KNDMLKOK_1	65975	66784	STU_RS16245	0.0	Capsule	Immune modulation	93.09	100.00	WP_002948020
KNDMLKOK_1	61934	63718	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
KNDMLKOK_1	66768	67724	STU_RS16250	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226328
KNDMLKOK_1	67721	68869	STU_RS16255	0.0	Capsule	Immune modulation	92.34	100.00	WP_041828290
KNDMLKOK_1	64770	65975	STU_RS16240	0.0	Capsule	Immune modulation	92.12	100.00	WP_011226326
KNDMLKOK_4	56268	56999	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
KNDMLKOK_7	24588	25181	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
KNDMLKOK_7	24588	25181	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
KNDMLKOK_7	24588	25181	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
KNDMLKOK_4	56268	56999	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
KNDMLKOK_7	23719	24588	rfbA	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681286
KNDMLKOK_1	63715	64749	STU_RS16235	0.0	Capsule	Immune modulation	91.10	99.15	WP_002948022
KNDMLKOK_4	56268	56999	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
KNDMLKOK_14	20614	21453	cbpD	0.0	Autolysin	Exoenzyme	90.96	99.88	WP_011226733
KNDMLKOK_4	167749	169407	fbp54	0.0	FBPs	Adherence	90.48	99.94	WP_011227179
KNDMLKOK_13	23330	24340	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
KNDMLKOK_4	57008	57700	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
KNDMLKOK_4	57008	57700	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
KNDMLKOK_4	57008	57700	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
KNDMLKOK_2	55810	57113	eno	0.0	Streptococcal enolase	Exoenzyme	87.25	99.54	WP_000022832
KNDMLKOK_5	114957	115718	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
KNDMLKOK_7	25453	26499	rfbB	0.0	Capsule	Immune modulation	80.92	99.90	WP_009659423
KNDMLKOK_3	213218	214501	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
KNDMLKOK_4	68009	68594	SPD_RS01775	4.12e-147	Capsule	Immune modulation	82.96	96.53	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KNDMLKOK_5	118406	119380	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
KNDMLKOK_5	106822	105749	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
KNDMLKOK_1	249390	251696	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
KNDMLKOK_2	144384	143416	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
KNDMLKOK_8	36719	35238	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
KNDMLKOK_5	87279	85033	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
KNDMLKOK_14	35875	34904	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
KNDMLKOK_10	97362	99092	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
KNDMLKOK_1	87044	85056	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
KNDMLKOK_1	115413	114262	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
KNDMLKOK_11	37017	35539	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
KNDMLKOK_2	57113	55812	Eno	0.0	enolase	86.44	99.77	ABP90468
KNDMLKOK_11	21644	19752	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
KNDMLKOK_5	82114	83823	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
KNDMLKOK_14	2036	945	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KNDMLKOK_6	28537	29547	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
KNDMLKOK_4	149176	150537	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
KNDMLKOK_2	71517	70627	bglB	1.84e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
KNDMLKOK_5	42847	43797	SP_0676	2.75e-170	transcription facot	81.39	98.45	AAK74821
KNDMLKOK_5	84846	83989	metF	4.35e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
KNDMLKOK_8	99275	99946	rr01	2.16e-127	response regulator	84.82	99.56	CAB54566
KNDMLKOK_4	1826	2530	covR	8.63e-127	responder protein	85.53	100.00	AAK71319
KNDMLKOK_5	78147	77476	ciaR	1.62e-124	two component system response regulator	85.71	99.12	AIK75708
KNDMLKOK_5	78147	77479	CiaR	1.63e-124	two-component response regulator	87.00	99.55	AAK74935
KNDMLKOK_4	1826	2530	walR	1.96e-120	DNA-binding response regulator	82.13	100.00	ANC99504
KNDMLKOK_3	63346	62660	CovR	4.73e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
KNDMLKOK_14	771	376	SpxA2	3.94e-76	transcriptional regulator	91.67	100.00	ERL21461
KNDMLKOK_4	137708	137307	SpxA1	3.97e-70	transcriptional regulator	82.84	100.00	ERL19273
KNDMLKOK_12	6604	6191	GrpE	3.80e-68	protein grpE	81.88	80.59	ABP89267
KNDMLKOK_3	30655	30368	spr0479	4.58e-48	essential gene	85.42	98.97	AAK99283
KNDMLKOK_2	178141	177887	spr1327	1.46e-44	essential gene	92.94	100.00	AAL00131
KNDMLKOK_6	120669	120932	spr0175	7.65e-43	pathogenitcity related	85.23	100.00	AAK98979
KNDMLKOK_6	121493	121759	spr0177	1.70e-41	essential gene	83.15	88.12	AAK98981
KNDMLKOK_3	213051	212560	RopE (M5005_Spy_1611)	1.05e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
KNDMLKOK_1	249390	251690	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
KNDMLKOK_6	64985	63966	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451