Genome ID：GCA_008305695.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
3	14	31	34.15

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
KPOFLCPA_1	397403	399322	tet(M)	ARO:3000186	tet(M)	90.77	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
KPOFLCPA_1	864626	866089	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
KPOFLCPA_1	863289	864506	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667
KPOFLCPA_1	397403	399321	tet(M)	Doxycycline, Tetracycline, Minocycline	95.15	99.95	JN846696

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
KPOFLCPA_1	863289	864503	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
KPOFLCPA_1	864626	866086	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1
KPOFLCPA_1	397403	399319	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	98.28	100.00	WP_011860841.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KPOFLCPA_1	1166621	1167352	STR_RS05260	0.0	Capsule	Immune modulation	94.54	100.00	WP_011227248
KPOFLCPA_1	1166621	1167352	STU_RS14645	0.0	Capsule	Immune modulation	93.85	100.00	WP_011226048
KPOFLCPA_1	1166621	1167352	STER_RS05315	0.0	Capsule	Immune modulation	93.58	100.00	WP_011681176
KPOFLCPA_1	1845524	1846374	rfbD	0.0	Capsule	Immune modulation	92.95	99.88	WP_014621820
KPOFLCPA_1	1273983	1275640	fbp54	0.0	FBPs	Adherence	91.44	99.88	WP_011227179
KPOFLCPA_1	1165161	1166620	STER_RS05320	0.0	Capsule	Immune modulation	91.26	99.79	WP_011681177
KPOFLCPA_1	1017218	1017811	STR_RS05880	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
KPOFLCPA_1	1017218	1017811	STER_RS06030	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
KPOFLCPA_1	1017218	1017811	STU_RS15260	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
KPOFLCPA_1	1165161	1166620	STU_RS14650	0.0	Capsule	Immune modulation	90.65	99.93	WP_011226049
KPOFLCPA_1	1165161	1166620	STR_RS05265	0.0	Capsule	Immune modulation	89.97	99.93	WP_041827043
KPOFLCPA_1	1167361	1168053	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
KPOFLCPA_1	1167361	1168053	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
KPOFLCPA_1	1167361	1168053	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
KPOFLCPA_1	842429	843732	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
KPOFLCPA_1	1924500	1925339	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
KPOFLCPA_1	361256	362266	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.28	99.80	WP_002986042
KPOFLCPA_1	1438544	1439305	srtA	0.0	Sortase A	Exoenzyme	83.88	99.87	-
KPOFLCPA_1	1018081	1019127	rfbB	0.0	Capsule	Immune modulation	83.40	99.90	WP_002263087
KPOFLCPA_1	14409	15692	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
KPOFLCPA_1	1016349	1017218	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
KPOFLCPA_1	1168063	1168733	STU_RS14635	2.84e-148	Capsule	Immune modulation	81.13	90.28	WP_011226046
KPOFLCPA_1	1168063	1168733	STER_RS05305	1.32e-146	Capsule	Immune modulation	80.98	90.28	WP_011681174
KPOFLCPA_1	1168063	1168733	STR_RS05250	1.34e-136	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KPOFLCPA_1	1441995	1442978	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
KPOFLCPA_1	1430406	1429333	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
KPOFLCPA_1	541371	539065	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
KPOFLCPA_1	754563	755531	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
KPOFLCPA_1	1573785	1575266	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
KPOFLCPA_1	1410287	1408041	metE	0.0	methionine biosynthesis enzymes	92.66	100.00	AAK74738
KPOFLCPA_1	142321	141350	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
KPOFLCPA_1	990972	992702	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
KPOFLCPA_1	671404	672555	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
KPOFLCPA_1	1859814	1857826	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
KPOFLCPA_1	177734	179212	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
KPOFLCPA_1	842429	843730	Eno	0.0	enolase	86.44	99.77	ABP90468
KPOFLCPA_1	193514	195406	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
KPOFLCPA_1	1405123	1406832	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
KPOFLCPA_1	103905	102814	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KPOFLCPA_1	311396	310386	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
KPOFLCPA_1	1258996	1260357	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
KPOFLCPA_1	828010	828900	bglB	2.43e-176	putative phospho--glucosidase	87.20	99.66	AAK33487
KPOFLCPA_1	1363560	1364510	SP_0676	3.31e-169	transcription facot	81.39	98.45	AAK74821
KPOFLCPA_1	1407851	1406994	metF	1.09e-168	methionine biosynthesis enzymes	87.76	99.31	AAK74739
KPOFLCPA_1	954106	953249	mtsA	6.42e-151	substrate-binding lipoprotein of manganese transporter	80.49	92.86	AIK76191
KPOFLCPA_1	1846374	1845535	GacA	6.59e-149	dTDP-4-dehydrorhamnose reductas	80.00	98.59	AAZ51220
KPOFLCPA_1	1510068	1509397	rr01	4.82e-126	response regulator	84.82	99.56	CAB54566
KPOFLCPA_1	1130545	1131249	covR	1.00e-125	responder protein	85.53	100.00	AAK71319
KPOFLCPA_1	1400446	1399775	ciaR	2.15e-124	two component system response regulator	86.16	99.12	AIK75708
KPOFLCPA_1	1400446	1399778	CiaR	3.98e-124	two-component response regulator	87.44	99.55	AAK74935
KPOFLCPA_1	2061479	2060793	CovR	1.88e-119	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
KPOFLCPA_1	1130545	1131249	walR	2.27e-119	DNA-binding response regulator	82.13	100.00	ANC99504
KPOFLCPA_1	102641	102246	SpxA2	2.21e-74	transcriptional regulator	91.67	100.00	ERL21461
KPOFLCPA_1	1246779	1246378	SpxA1	4.94e-68	transcriptional regulator	81.34	100.00	ERL19273
KPOFLCPA_1	35457	35071	GrpE	6.05e-63	protein grpE	82.95	75.29	ABP89267
KPOFLCPA_1	14242	13751	RopE (M5005_Spy_1611)	1.09e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
KPOFLCPA_1	541371	539071	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
KPOFLCPA_1	274973	275992	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451